Commonwealth Fusion is a research company that develops energy through an inexhaustible power plant. It uses rare-earth barium copper oxide superconductor technology to develop energy. They combine proven physics backed by decades of government-funded fusion research with a revolutionary superconducting magnet technology to accelerate the path to commercial fusion energy Commonwealth Fusion Systems (CFS) is on track to bring fusion energy technology to the market. CFS was spun out of MIT and is collaborating with MIT’s Plasma Science and Fusion Center to leverage decades of research combined with the innovation and speed of the private sector. The business designs and builds fusion machines that deliver limitless and clean fusion energy and integrate proven physics with magnet technology, allowing clients to contribute to the expansion of renewable energy while mitigating the effects of climate change.
JETCOOL Technologies develops microjet cooling modules for advanced electronics, publishing the results in several papers. The technology behind JETCOOL was developed at MIT Lincoln Laboratory, by a team led by Bernie Malouin. It was founded in 2019 and is based in Littleton, Massachusetts.
Wren Therapeutics is a biopharmaceutical company based in Cambridge UK, focused on drug discovery and development for protein misfolding diseases, which include Alzheimer’s and Parkinson’s diseases, type-2 diabetes, and many rare forms of amyloidosis. Wren’s proprietary technology platform is built on new and fundamental understanding of the origins of these diseases and is based on decades of scientific research at the University of Cambridge and Lund University. Wren is using this platform to develop small molecule therapeutics for multiple protein misfolding diseases, including major neurological and rare disorders.
Cullinan Pearl develops an orally available tyrosine kinase inhibitor to target Epidermal Growth Factor Receptor exon 20 mutations. Cullinan Pearl is a subsidiary of Cullinan Oncology.
Zippity LLC is a provider of onsite car maintenance and repair services, founded in 2015 and based in Boston, Massachusetts. The company specializes in delivering car care directly at the customer’s workplace, offering a seamless, tech-enabled experience that simplifies vehicle maintenance. Customers can schedule and pay for services online, allowing them to leave their keys on the service day without the need for transportation to a traditional mechanic. Zippity utilizes a specially designed enclosed service trailer to perform a range of maintenance tasks, including oil changes, brake servicing, and tire work, in any parking lot regardless of weather conditions. This innovative approach aims to alleviate the typical frustrations associated with car ownership, providing a convenient solution that caters to the busy lifestyles of modern consumers.
Breezeway is a mobile solution for intelligent property care and maintenance. Combining robust property profiles with straightforward task management, Breezeway enables managers and owners to improve the quality and efficiency of their operations and enjoy seamless rental turnovers. Its clients leverage Breezeway's integrated platform to conduct inspections, monitor property cleaning and readiness, and coordinate tasks with internal staff or remote service partners.
Commonwealth Fusion is a research company that develops energy through an inexhaustible power plant. It uses rare-earth barium copper oxide superconductor technology to develop energy. They combine proven physics backed by decades of government-funded fusion research with a revolutionary superconducting magnet technology to accelerate the path to commercial fusion energy Commonwealth Fusion Systems (CFS) is on track to bring fusion energy technology to the market. CFS was spun out of MIT and is collaborating with MIT’s Plasma Science and Fusion Center to leverage decades of research combined with the innovation and speed of the private sector. The business designs and builds fusion machines that deliver limitless and clean fusion energy and integrate proven physics with magnet technology, allowing clients to contribute to the expansion of renewable energy while mitigating the effects of climate change.
Zippity LLC is a provider of onsite car maintenance and repair services, founded in 2015 and based in Boston, Massachusetts. The company specializes in delivering car care directly at the customer’s workplace, offering a seamless, tech-enabled experience that simplifies vehicle maintenance. Customers can schedule and pay for services online, allowing them to leave their keys on the service day without the need for transportation to a traditional mechanic. Zippity utilizes a specially designed enclosed service trailer to perform a range of maintenance tasks, including oil changes, brake servicing, and tire work, in any parking lot regardless of weather conditions. This innovative approach aims to alleviate the typical frustrations associated with car ownership, providing a convenient solution that caters to the busy lifestyles of modern consumers.
Commonwealth Fusion is a research company that develops energy through an inexhaustible power plant. It uses rare-earth barium copper oxide superconductor technology to develop energy. They combine proven physics backed by decades of government-funded fusion research with a revolutionary superconducting magnet technology to accelerate the path to commercial fusion energy Commonwealth Fusion Systems (CFS) is on track to bring fusion energy technology to the market. CFS was spun out of MIT and is collaborating with MIT’s Plasma Science and Fusion Center to leverage decades of research combined with the innovation and speed of the private sector. The business designs and builds fusion machines that deliver limitless and clean fusion energy and integrate proven physics with magnet technology, allowing clients to contribute to the expansion of renewable energy while mitigating the effects of climate change.
Censinet is a SaaS company in healthcare cybersecurity that provides a two-sided network platform for third-party risk assessments. It connects healthcare providers and their third-party vendors so they can efficiently manage and reduce risk in real time.
SeLux Diagnostics is a developer of the next-generation phenotyping platform that provides personalized antimicrobial therapies to patients. The company is revolutionizing patient care by expediting the selection of personalized antimicrobial therapy for all infectious disease patients. This advancement will save lives, reduce hospital stays, and address the escalating antibiotic resistance epidemic by minimizing the overuse of broad-spectrum agents.
Remedy Plan Therapeutics is a pre-clinical-stage company developing small molecule therapeutics to halt tumor growth and disrupt the cancer stem cells that cause metastasis. Our approach is to develop effective, non-toxic treatments that target the dangerous embryonic properties of cancer stem cells, which form the basis for cancer growth, spread, and resistance to chemotherapy. Remedy Plan is positioned to deliver one first-in-class drug candidate for Phase I clinical development approximately 15 months after Series A funding Remedy Plan's proprietary drug screening platform identifies drug candidates that differentiate cancer stem cells, disrupt proliferation, and inhibit formation of new tumors. From the initial screen of 40,000 drug components, a lead candidate is currently undergoing optimization and mechanism of action studies in preparation for Phase I clinical trials. With the second screen of over 100,000 drug components completed, Remedy Plan aims to have at least two drugs in clinical development by 2020.
SRS Medical is a leading manufacturer of devices for the diagnosis of voiding disorders and for conservative treatments of urinary incontinence. It is a privately held corporation with facilities in Redmond WA and Billerica MA.
Spotted helps brands and agencies make smarter, safer celebrity partnership decisions. Spotted is the authority in celebrity data and research offering celebrity-brand fit, celebrity risk assessment, celebrity personality assessment, and predictive analytics.
SRS Medical is a leading manufacturer of devices for the diagnosis of voiding disorders and for conservative treatments of urinary incontinence. It is a privately held corporation with facilities in Redmond WA and Billerica MA.
Censinet is a SaaS company in healthcare cybersecurity that provides a two-sided network platform for third-party risk assessments. It connects healthcare providers and their third-party vendors so they can efficiently manage and reduce risk in real time.
ExIthera Pharmaceuticals is a developer of an early-stage biotechnology platform used to develop small-molecule pharmaceuticals. The company's stroke prevention and antithrombosis drugs are based on the unique pathophysiological role of Factor XI in the initiation of intravascular thrombi without causing undue bleeding. It focuses on developing stroke prevention and anti-thrombosis drugs based on Factor XI, which has a pathophysiological role in the initiation of intravascular thrombi without causing undue bleeding, enabling physicians to treat serious consequences, including venous thromboembolism, deep vein thrombosis, stroke, and heart attack.
Millstone provider of outsourced quality-critical services for medical manufacturers. The Company is strategically positioned to benefit from several strong secular trends, including increased demand for outsourced post-manufacturing services and significant growth in robotic-assisted surgery.
When video workflows operate like a well-oiled machine, teams can stop worrying about security and focus on producing better content, faster and more efficiently. MediaSilo is a video management platform for distributed media production teams that need to manage, share and approve content safely and easily. The Boston, MA-based company works with media companies, advertising agencies and content creators to provide lightweight SaaS software that sits in the middle of video lifecycles, working with existing tools and workflows to keep teams connected, assets secure and stories beautifully and seamlessly presented. With 550+ customers, 100k+ monthly users and 10M+ assets managed, MediaSilo continues to innovate and provide solutions that span media, entertainment and enterprise video, with a focus on security. Most recently, MediaSilo launched SafeStream, an on-demand watermarking technology that acts as a visual deterrant to piracy. Each watermarked video is created in real-time and is personalized to the person requesting or viewing the asset. Because the customized watermark is inserted in near real-time (less than a 20-second delay) – even for a 90-minute video – the speed and cost-effectiveness of SafeStream is unheard of the industry, and is not interruptive to the viewing experience. The content owner remains in complete control of where and how the watermark appears on the video. It can be incorporated directly into workflows so it can be easily used to protect dailies and rough cuts in addition to finished content.
F&B Asia is driven to develop quality dining concepts within the Southeast Asia region. The company is into food services and hospitality that looks to grow strong Food and Beverage brands across multiple geographies, formats and cuisines.
East Point Capital is an investment and real estate development company. They hold and manage securities for investment purposes, but they offer investors a variety of funds and investment services, which include portfolio management, recordkeeping, custodial, legal, accounting, and tax management services.
4G Clinical provides software and services for clinical drug trials specifically in the randomization and trial supply management (RTSM) space. The solution, Prancer RTSM utilizes natural language processing alongside integrated clinical supplies forecasting and management functionality to slash development timelines, increase operational efficiencies, and offer exceptional quality. It also offers global expertise and advisory services to pharmaceutical companies and contracts research organizations. 4G Clinical was founded in 2015 and is headquartered in Wellesley, MA, USA.
ExIthera Pharmaceuticals is a developer of an early-stage biotechnology platform used to develop small-molecule pharmaceuticals. The company's stroke prevention and antithrombosis drugs are based on the unique pathophysiological role of Factor XI in the initiation of intravascular thrombi without causing undue bleeding. It focuses on developing stroke prevention and anti-thrombosis drugs based on Factor XI, which has a pathophysiological role in the initiation of intravascular thrombi without causing undue bleeding, enabling physicians to treat serious consequences, including venous thromboembolism, deep vein thrombosis, stroke, and heart attack.
Spotted Media, Inc. specializes in disgrace insurance solutions, offering coverage for events that could harm productions, campaigns, tours, teams, and companies. The firm serves a diverse clientele that includes studios, production companies, networks, brand advertisers, sports teams and leagues, financiers, and music labels. Additionally, Spotted provides valuable insights for brands and agencies regarding celebrity partnerships, focusing on celebrity-brand fit, risk assessment, personality evaluation, and predictive analytics. Founded in 2015, Spotted Media is headquartered in Boston, Massachusetts.
Maxwell Health simplifies benefits and HR for small-to-mid-sized employers. The platform includes a marketplace that makes buying benefits intuitive for employees, tools that streamline HR processes including benefits administration and payroll, and a mobile app that makes using benefits easy. Their purpose is to help American families achieve health and financial well-being by modernizing how employees experience insurance, financial, and wellness benefits. The platform is provided by benefits advisors as well as insurance and retirement companies that license their technology. It was founded in 2012 and is headquartered in Boston, Massachusetts.
Cyft partners with leading care organizations to optimize care management for chronic / complex, behavioral health, and dual-eligible populations. Cyft empowers Medicaid plans interested in moving beyond simplistic one size fits all approaches. By capitalizing on all available data to inform care management strategies, populate programs, and measure progress, Medicaid plans improve the health of both their members and their financials. Cyft is technology-enabled, using all relevant data - from claims to HRAs to case management notes - to match cost savings and revenue generating interventions to those most likely to benefit. However, real progress in care management is only ever achieved via a deep understanding of process and implementation of best practices. Toward that end, Cyft's team of healthcare experts works closely with partners to understand, design, and integrate results into existing systems and workflows. This high tech + high touch approach has helped 20+ plans capitalize on their existing data and talent to realize >$100M in cost savings and new revenue and improved member retainment and satisfaction.
4G Clinical provides software and services for clinical drug trials specifically in the randomization and trial supply management (RTSM) space. The solution, Prancer RTSM utilizes natural language processing alongside integrated clinical supplies forecasting and management functionality to slash development timelines, increase operational efficiencies, and offer exceptional quality. It also offers global expertise and advisory services to pharmaceutical companies and contracts research organizations. 4G Clinical was founded in 2015 and is headquartered in Wellesley, MA, USA.
Cartesian Therapeutics is a fully integrated, clinical-stage biopharmaceutical company developing novel cell and gene immunotherapies to treat cancer and autoimmune diseases.
Zixi is the leading enabler of flawless broadcast quality HDTV over the Internet. Broadcasters, enterprises, and video-on-demand services use Jixi to enrich the user experience, create new services, and significantly reduce costs. Jixi enables the delivery of live and on-demand HD video content over the Internet in real time and with unprecedented quality. The technology is applicable for multi-media delivery and consumption across a spectrum of industries.
Emerald was founded in 2010 by two scientists and life-long friends from Philadelphia with a singular vision of how a biotechnology company should run. Frustrated by the continual deceleration of innovation and the exponentially increasing R&D costs in the pharmaceutical sector, Emerald models itself after the legendary start-up companies of the mid-20th century that built the core technologies underlying the meteoric rise of the semiconductor industry. The team places as much focus on building tools around how scientific research is conducted as they do on their proprietary anti-viral therapies. In this way, Emerald is striving to bring a Moore’s law-like acceleration to life sciences innovation.
Fashion Project is the first designer shopping experience featuring exclusive apparel, shoes, and accessories that are generously donated by style icons, celebrities, and philanthropists from around the world. The majority of each sale is donated to charity. It was founded in 2011 and headquartered in Boston, Massachusetts.
Maxwell Health simplifies benefits and HR for small-to-mid-sized employers. The platform includes a marketplace that makes buying benefits intuitive for employees, tools that streamline HR processes including benefits administration and payroll, and a mobile app that makes using benefits easy. Their purpose is to help American families achieve health and financial well-being by modernizing how employees experience insurance, financial, and wellness benefits. The platform is provided by benefits advisors as well as insurance and retirement companies that license their technology. It was founded in 2012 and is headquartered in Boston, Massachusetts.
ExIthera Pharmaceuticals is a developer of an early-stage biotechnology platform used to develop small-molecule pharmaceuticals. The company's stroke prevention and antithrombosis drugs are based on the unique pathophysiological role of Factor XI in the initiation of intravascular thrombi without causing undue bleeding. It focuses on developing stroke prevention and anti-thrombosis drugs based on Factor XI, which has a pathophysiological role in the initiation of intravascular thrombi without causing undue bleeding, enabling physicians to treat serious consequences, including venous thromboembolism, deep vein thrombosis, stroke, and heart attack.
RailComm is a global leader in the design and implementation of rail automation systems and software for the freight, transit, and industrial markets. Their solutions range from yard automation solutions including automated switching, wireless remote control, dynamic yard mapping to mainline automation which includes CTC, dark territory control, and server-based software platforms. For more than 14 years, RailComm has served the leading rail operators in North America, Latin America, and Africa. They bring a collaborative focus to automation; working closely with their clients to implement solutions that deliver immediate ROI and that are expressly designed with the flexibility and scalability to grow with your operation.
Allergan is a $23 billion diversified global pharmaceutical company and a leader in a new industry model - Growth Pharma. The company is anchored by strong and sustainable brand franchises, a leading global generics business, a premier pipeline, highly efficient operations and an experienced management team creating an unrivaled foundation for long-term growth. Driving continued innovation and growth is the combined company’s strong commitment to R&D, with an investment of ~$1.7 billion in 2015, focused on strategic development of innovative and durable value-enhancing products within brands, generics, biologics and OTC portfolios. The Company’s Generics portfolio features more than 1,000 generics, branded generics, established brands and OTC products. The Company is the third largest generic manufacturer in the U.S. and holds a top 5 leadership position in nearly 20 International markets. Allergan has global headquarters in Dublin, Ireland and U.S. Administrative Headquarters in Parsippany, New Jersey, USA.
Emerald was founded in 2010 by two scientists and life-long friends from Philadelphia with a singular vision of how a biotechnology company should run. Frustrated by the continual deceleration of innovation and the exponentially increasing R&D costs in the pharmaceutical sector, Emerald models itself after the legendary start-up companies of the mid-20th century that built the core technologies underlying the meteoric rise of the semiconductor industry. The team places as much focus on building tools around how scientific research is conducted as they do on their proprietary anti-viral therapies. In this way, Emerald is striving to bring a Moore’s law-like acceleration to life sciences innovation.
Seventh Generation produces and distributes safe household products including disinfectants, soaps, and personal care products.The company lives its commitment to "caring today for seven generations of tomorrows," with products formulated to provide mindful solutions for you, your family, and your home -- and for the community and environment outside of it. Founded in 1988, the company began creating plant-based products that are safe, effective and focused on human health and the environment. Each and every one of its product, from laundry detergents to diapers and surface cleaners, are made ethically (no animal testing takes place) and from natural ingredients. This is the company of choice if you’re looking for powerful cleaning products that are non-toxic, sustainable and have a minimal impact on the environment.
Mimetogen Pharmaceuticals Inc. is a clinical-stage ophthalmology drug development company developing peptidomimetics for dry eye, retinitis pigmentosa, dry AMD and glaucoma.
CustomMade is an online marketplace connecting Buyers who want one-of-a-kind creations with professional and passionate Makers of those goods. Born in 1996 with the vision to help people find the unique gifts, objects and goods they cannot find through traditional retail channels, CustomMade has grown from a community of 350 carpenters to more than 12,000 Makers of all trades since its acquisition in 2009. For more information, visit www.custommade.com, Facebook, Linkedin, +CustomMade, @CustomMade.
Fashion Project is the first designer shopping experience featuring exclusive apparel, shoes, and accessories that are generously donated by style icons, celebrities, and philanthropists from around the world. The majority of each sale is donated to charity. It was founded in 2011 and headquartered in Boston, Massachusetts.
When video workflows operate like a well-oiled machine, teams can stop worrying about security and focus on producing better content, faster and more efficiently. MediaSilo is a video management platform for distributed media production teams that need to manage, share and approve content safely and easily. The Boston, MA-based company works with media companies, advertising agencies and content creators to provide lightweight SaaS software that sits in the middle of video lifecycles, working with existing tools and workflows to keep teams connected, assets secure and stories beautifully and seamlessly presented. With 550+ customers, 100k+ monthly users and 10M+ assets managed, MediaSilo continues to innovate and provide solutions that span media, entertainment and enterprise video, with a focus on security. Most recently, MediaSilo launched SafeStream, an on-demand watermarking technology that acts as a visual deterrant to piracy. Each watermarked video is created in real-time and is personalized to the person requesting or viewing the asset. Because the customized watermark is inserted in near real-time (less than a 20-second delay) – even for a 90-minute video – the speed and cost-effectiveness of SafeStream is unheard of the industry, and is not interruptive to the viewing experience. The content owner remains in complete control of where and how the watermark appears on the video. It can be incorporated directly into workflows so it can be easily used to protect dailies and rough cuts in addition to finished content.
CustomMade is an online marketplace connecting Buyers who want one-of-a-kind creations with professional and passionate Makers of those goods. Born in 1996 with the vision to help people find the unique gifts, objects and goods they cannot find through traditional retail channels, CustomMade has grown from a community of 350 carpenters to more than 12,000 Makers of all trades since its acquisition in 2009. For more information, visit www.custommade.com, Facebook, Linkedin, +CustomMade, @CustomMade.
SHIFT is a provider of cloud-based media collaboration and digital asset management solutions. SHIFT is the pioneer of media-specific collaboration software tools tailored for media & entertainment enterprises, brands and agencies.
Nanoscale Powders develops low boron, low phosphorous silicon metal from commercial chemicals. They offer a range of products including titanium metal, alloys, and intermetallic powders. They also produce silicon alloy powders for lithium ion anode development.
Best Doctors is a provider of medical consultation services that enhances the quality and affordability of healthcare through its innovative employee health benefits. The company specializes in offering access to world-class medical expertise, enabling members to make informed decisions regarding their health. By facilitating inter-consultations, Best Doctors connects patients with leading medical professionals who review their diagnoses and treatment plans in detail. This process ensures that individuals receive accurate diagnoses and appropriate treatment recommendations, accompanied by clear and understandable reports. Ultimately, Best Doctors aims to empower its members to navigate complex medical decisions confidently, thereby improving their overall healthcare experience.
Zixi is the leading enabler of flawless broadcast quality HDTV over the Internet. Broadcasters, enterprises, and video-on-demand services use Jixi to enrich the user experience, create new services, and significantly reduce costs. Jixi enables the delivery of live and on-demand HD video content over the Internet in real time and with unprecedented quality. The technology is applicable for multi-media delivery and consumption across a spectrum of industries.
IndoStar Capital is a financial company that provides structured-term financing solutions to corporations, vehicle finance, home finance, and SME finance. They provide vehicle finance for commercial vehicles, farm equipment, four-wheelers, and two-wheelers. It also offers several sectors, including real estate, steel, cement, media and entertainment, dairy, financial services, and pharmaceuticals.
SRS Medical is a leading manufacturer of devices for the diagnosis of voiding disorders and for conservative treatments of urinary incontinence. It is a privately held corporation with facilities in Redmond WA and Billerica MA.
Seventh Generation produces and distributes safe household products including disinfectants, soaps, and personal care products.The company lives its commitment to "caring today for seven generations of tomorrows," with products formulated to provide mindful solutions for you, your family, and your home -- and for the community and environment outside of it. Founded in 1988, the company began creating plant-based products that are safe, effective and focused on human health and the environment. Each and every one of its product, from laundry detergents to diapers and surface cleaners, are made ethically (no animal testing takes place) and from natural ingredients. This is the company of choice if you’re looking for powerful cleaning products that are non-toxic, sustainable and have a minimal impact on the environment.
StyleFeeder is a social bookmarking service targeted specifically at shopping. StyleFeeder allows users to browse the web and add clothing, gadgets, or other items they find to their StyleFeed, which they can then share with friends. The service also analyzes the items a person adds, enabling it to create personalized recommendations and an improved shopping search engine. Additionally, StyleFeeder has created widgets that display a user's StyleFeed, and can be added to profiles at social networks such as [Facebook](http://crunchbase.com/organization/facebook) or [Myspace](http://crunchbase.com/organization/myspace), or blogs or personal websites. StyleFeeder has some social networking capabilities built into its own site, as well. For example, it identifies users with similar tastes, called StyleTwins, and makes it easy for these users to get to know each other. The social shopping space is becoming fairly crowded, and StyleFeeder's competitors include [StylePath](http://www.crunchbase.com/organization/stylepath), another Boston-based start-up, as well as eBay's new Neighborhoods product.
StyleFeeder is a social bookmarking service targeted specifically at shopping. StyleFeeder allows users to browse the web and add clothing, gadgets, or other items they find to their StyleFeed, which they can then share with friends. The service also analyzes the items a person adds, enabling it to create personalized recommendations and an improved shopping search engine. Additionally, StyleFeeder has created widgets that display a user's StyleFeed, and can be added to profiles at social networks such as [Facebook](http://crunchbase.com/organization/facebook) or [Myspace](http://crunchbase.com/organization/myspace), or blogs or personal websites. StyleFeeder has some social networking capabilities built into its own site, as well. For example, it identifies users with similar tastes, called StyleTwins, and makes it easy for these users to get to know each other. The social shopping space is becoming fairly crowded, and StyleFeeder's competitors include [StylePath](http://www.crunchbase.com/organization/stylepath), another Boston-based start-up, as well as eBay's new Neighborhoods product.
Top10 Media
Venture Round in 2006
Top10 Media provides online networking services for publishing and retail applications. Its services allow users to tap into blogs, podcasts, video, and mainstream news outlets on the Web. The company also offers a set of algorithms that automatically categorize and rank user-generated and other Web-based content. Top10 Media, Inc. was founded in 2005 and is headquartered in Cambridge, Massachusetts.
ExecuTrain is an IT company that offers a range of services and solutions to its clients. ExecuTrain’s range of services include classroom training, live VILT, e-learning support, and training room rentals. Its range of solutions consist of learning program management, performance support, and custom development. Furthermore, it provides courses in Microsoft office, technical, cisco, VMware, information security, ITIL, Amazon web services, programming, Linux, adobe, and business skills. ExecuTrain was founded in 1984 by Andy Atkins and is based in Georgia.
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