Sound Bioventures

AnaCardio is a clinical stage biopharmaceutical company focused on developing innovative drugs for the treatment of heart failure. The company's therapeutics aim to enhance the contractility of the heart muscle through a unique mechanism that utilizes a therapeutic peptide. This approach is designed to avoid common adverse effects associated with traditional treatments, such as tachycardia, arrhythmia, ischemia, or hypotension. By improving cardiac output safely, AnaCardio's drugs have the potential to enhance organ function, elevate quality of life, increase functional capacity, and lower the risks of hospitalization and mortality for patients suffering from heart failure.

Artax Biopharma Inc. is a biotechnology company focused on developing therapies for autoimmune and inflammatory diseases. Incorporated in 2013 and headquartered in Cambridge, Massachusetts, the company specializes in small-molecule drugs that modulate immune responses. Its lead compound, AX-024, selectively inhibits the interaction between T-cell receptors and Nck, which plays a crucial role in T-cell activation. This mechanism allows for the suppression of harmful immune reactions against self-tissues while maintaining the body's ability to combat infections. Artax Biopharma’s research portfolio includes therapies targeting conditions such as asthma, rheumatoid arthritis, psoriasis, graft-versus-host disease, and multiple sclerosis, aiming to provide innovative treatments with reduced side effects for patients suffering from these complex health issues.

Theolytics Limited is a clinical-stage biotechnology company based in Oxford, United Kingdom, specializing in the development of oncolytic viral therapies to combat cancer. Founded in 2017, Theolytics utilizes a phenotypic screening platform that facilitates the discovery and development of effective, targeted therapeutic candidates designed for intravenous delivery. The company's innovative approach is aimed at creating category-changing cancer treatments that can address both solid and liquid tumors. In addition to advancing its internal pipeline of programs, Theolytics is also forming strategic partnerships to enhance and expedite the development of its therapeutic offerings, ultimately striving to provide innovative care options for patients.

AbolerIS Pharma is a biotechnology company based in Nantes, France, specializing in the development of immune-modulators aimed at treating transplant rejection, graft-versus-host disease, and autoimmune diseases. Incorporated in 2019, the company offers innovative products such as Anti-CD45RC, a monoclonal antibody designed to deplete effector T cells, and IL-34, a cytokine that promotes the induction of tolerogenic macrophages and regulatory T cells. AbolerIS Pharma employs a unique therapeutic approach that fosters immune tolerance while preserving beneficial immune responses in the context of inflammatory, autoimmune, and degenerative diseases. This strategy allows the company to focus on advancing novel drugs to address significant unmet medical needs in these therapeutic areas.

VarmX is a pharmaceutical spin-off from the Leiden University Medical Center, focused on the development and manufacturing of therapeutic proteins aimed at restoring blood clotting in patients experiencing bleeding. The company's lead product, PseudoXa, is a modified recombinant human coagulation factor X that can promptly reinstate blood clotting in patients using direct factor Xa anticoagulants, such as rivaroxaban, apixaban, and edoxaban. These anticoagulants, commonly prescribed for the prevention and treatment of thrombosis and stroke, often lead to severe bleeding as a side effect. PseudoXa addresses this critical issue by effectively stopping and preventing bleeding, thereby enhancing the safety of anticoagulant therapy for millions of patients worldwide.

Arthex Biotech S.L. is a biotechnology company founded in 2019 and based in Paterna, Spain. It specializes in the development of antisense RNA treatments specifically aimed at addressing genetic diseases and disorders where microRNAs play a significant role. As a spin-off from the University of Valencia, Arthex Biotech leverages a strong foundation in drug discovery and has a team comprising experts with extensive experience in neuromuscular diseases. The company focuses on creating innovative therapies for conditions with unmet medical needs, providing new treatment options for patients suffering from rare genetic diseases and other high-need medical issues. With guidance from esteemed scientific and clinical advisors, Arthex Biotech is committed to advancing its product development to improve patient outcomes.

Teitur Trophics is a biotech company established in 2020 and based in Aarhus, Denmark. The company specializes in the development of circular peptides aimed at addressing neurodegenerative diseases. Its research focuses on small peptides that interact with receptors central to neural function. By gaining insights into the biology of these receptors, Teitur Trophics aims to modulate key mechanisms in neural function, which may facilitate the creation of innovative treatments. These treatments are designed to be administered through daily injections, with the potential to prevent the onset of neurodegenerative conditions.

Breye Therapeutics, a Danish-based biopharmaceutical firm in the clinical stages, is working to provide cutting-edge oral treatments for the management of retinal vascular diseases.

Artax Biopharma Inc. is a biotechnology company focused on developing therapies for autoimmune and inflammatory diseases. Incorporated in 2013 and headquartered in Cambridge, Massachusetts, the company specializes in small-molecule drugs that modulate immune responses. Its lead compound, AX-024, selectively inhibits the interaction between T-cell receptors and Nck, which plays a crucial role in T-cell activation. This mechanism allows for the suppression of harmful immune reactions against self-tissues while maintaining the body's ability to combat infections. Artax Biopharma’s research portfolio includes therapies targeting conditions such as asthma, rheumatoid arthritis, psoriasis, graft-versus-host disease, and multiple sclerosis, aiming to provide innovative treatments with reduced side effects for patients suffering from these complex health issues.