Spruce Capital Partners

A.Team is a professional network that facilitates the formation of full-stack teams by connecting top independent product builders. Designed as an invite-only community, it brings together diverse tech talent with varied expertise to assist companies in adapting to digital disruptions. The platform enables organizations to pivot their products and explore new monetization strategies by assembling agile teams that can tackle areas outside their core competencies. By leveraging this network, companies can quickly access the skills and knowledge necessary to navigate the evolving technology landscape and achieve their goals.

GreenLight Biosciences, Inc. is a biotechnology company headquartered in Medford, Massachusetts, with an additional location in North Carolina. Founded in 2008, the company specializes in developing RNA-based solutions for agricultural and pharmaceutical purposes. It offers a proprietary technology platform that enables the efficient and cost-effective production of high-quality RNA, facilitating advancements in vaccine development, pandemic response, crop management, and the protection of pollinators. GreenLight develops mRNA-based vaccine candidates, including those aimed at preventing SARS-CoV-2 infections, and engages in collaborative efforts with industry leaders to further enhance its offerings. Through its innovative approach, GreenLight aims to contribute significantly to sustainable global development and food security.

Founded in 2016, Amfora is a biotechnology company based in San Francisco. It harnesses biology to sustainably enhance the nutritional density of food and feed crops, particularly focusing on increasing protein content through gene editing. The company aims to meet global demand for high-protein foods while reducing environmental impact.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

GreenLight Biosciences, Inc. is a biotechnology company headquartered in Medford, Massachusetts, with an additional location in North Carolina. Founded in 2008, the company specializes in developing RNA-based solutions for agricultural and pharmaceutical purposes. It offers a proprietary technology platform that enables the efficient and cost-effective production of high-quality RNA, facilitating advancements in vaccine development, pandemic response, crop management, and the protection of pollinators. GreenLight develops mRNA-based vaccine candidates, including those aimed at preventing SARS-CoV-2 infections, and engages in collaborative efforts with industry leaders to further enhance its offerings. Through its innovative approach, GreenLight aims to contribute significantly to sustainable global development and food security.

Pivot Bio, Inc. is a biotechnology company founded in 2010 and based in Emeryville, California. The company focuses on enhancing crop nutrition through a deep understanding of the microbiome, utilizing engineered microbes to deliver essential nutrients, protect against pests, and improve crop quality. By leveraging data science and engineering principles, Pivot Bio aims to map the dynamics of the plant microbiome and develop beneficial traits. Their proprietary ON Technology utilizes naturally occurring microbes to supply nitrogen to crops, offering a sustainable alternative to synthetic fertilizers. This innovation not only helps farmers increase yields but also contributes to reducing reliance on petrochemical fertilizers, ultimately promoting healthier ecosystems and cleaner air and water. Pivot Bio's current initiatives primarily focus on enabling microbes to fix and supply nitrogen for corn, addressing the growing need for sustainable agricultural practices as the global population expands.

Crop Enhancement LLC is an early-stage specialty materials company based in San Jose, California, founded in 2011. The company focuses on developing innovative anchoring and controlled-release formulation technologies for agricultural chemicals. Its advanced agrochemical formulations utilize environmentally friendly chemistry to enhance crop yields and profitability while minimizing the reliance on synthetic pesticides. Crop Enhancement's products include proprietary films that modify plant surfaces, improving resistance to pests and diseases. This approach not only supports sustainable farming practices but also enables precise delivery of active ingredients and fertilizers, ultimately benefiting growers through increased efficiency and reduced chemical use.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

Consumer Physics Inc. is a Tel Aviv-based company that develops and distributes molecular sensors, primarily marketed under the SCiO brand. Founded in 2011, the company aims to empower consumers and businesses to analyze the composition of materials in real-time using its compact near-infrared (NIR) spectrometer. The SCiO device integrates with smartphone applications and connects to a cloud-based database that stores material fingerprints. This technology is particularly beneficial for industries such as food and agriculture, as it enables users to make informed decisions, reduce waste, and enhance profitability. Consumer Physics also provides a platform for businesses and third-party developers to create their own molecular sensing models and mobile applications, supported by tools like the SCiO Lab development platform and Mobile SDK.

Inscripta, Inc. is a gene editing technology company based in Boulder, Colorado, with additional offices in Pleasanton and San Diego, California. Founded in 2015, Inscripta focuses on developing CRISPR enzymes, specifically MADzymes, for precision gene editing. The company has created a benchtop platform for scalable digital genome engineering, which includes an instrument, consumables, software, and assays that facilitate a fully automated workflow. This platform allows for massively parallel and trackable editing of single cells, significantly enhancing the scale and efficiency of gene editing research. By making its MAD7 CRISPR nuclease freely available for research and development, Inscripta aims to remove existing technical and licensing barriers, thereby empowering scientists and fostering a new era of biological discovery.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

Consumer Physics Inc. is a Tel Aviv-based company that develops and distributes molecular sensors, primarily marketed under the SCiO brand. Founded in 2011, the company aims to empower consumers and businesses to analyze the composition of materials in real-time using its compact near-infrared (NIR) spectrometer. The SCiO device integrates with smartphone applications and connects to a cloud-based database that stores material fingerprints. This technology is particularly beneficial for industries such as food and agriculture, as it enables users to make informed decisions, reduce waste, and enhance profitability. Consumer Physics also provides a platform for businesses and third-party developers to create their own molecular sensing models and mobile applications, supported by tools like the SCiO Lab development platform and Mobile SDK.

Evolve Biosystems, Inc. is a life sciences company based in Davis, California, that focuses on developing probiotic-based biotherapeutics aimed at establishing, restoring, and maintaining a healthy human microbiome. Incorporated in 2011, the company utilizes a discovery platform that addresses dysbiosis issues throughout the human life cycle and in production animals. Evolve Biosystems specializes in probiotic bacteria activated with specific prebiotic oligosaccharides and employs various delivery systems to support gut health, particularly in infants during their first six months of life. Their product offerings include consumer-directed solutions for home use as well as specialized products for neonatal intensive care units, addressing unmet clinical needs in both human and animal health.

Founded in 2016, Amfora is a biotechnology company based in San Francisco. It harnesses biology to sustainably enhance the nutritional density of food and feed crops, particularly focusing on increasing protein content through gene editing. The company aims to meet global demand for high-protein foods while reducing environmental impact.

Inscripta, Inc. is a gene editing technology company based in Boulder, Colorado, with additional offices in Pleasanton and San Diego, California. Founded in 2015, Inscripta focuses on developing CRISPR enzymes, specifically MADzymes, for precision gene editing. The company has created a benchtop platform for scalable digital genome engineering, which includes an instrument, consumables, software, and assays that facilitate a fully automated workflow. This platform allows for massively parallel and trackable editing of single cells, significantly enhancing the scale and efficiency of gene editing research. By making its MAD7 CRISPR nuclease freely available for research and development, Inscripta aims to remove existing technical and licensing barriers, thereby empowering scientists and fostering a new era of biological discovery.

Agerpoint is a geospatial intelligence and data engineering company that builds a precision farming insights platform. It combines artificial intelligence, high‑performance computing, computer vision and advanced analytics to fuse data from mobile devices, ground vehicles, autonomous robots, drones, satellites, and human observations into a highly precise, quantifiable digital record of natural environments. The platform delivers actionable information on crop yields, disease detection, carbon sequestration, and biodiversity, and provides comprehensive GIS‑based asset inventories for growers, researchers, forestry managers, and government agencies. Founded in 2012 and headquartered in Research Triangle Park, North Carolina, Agerpoint’s mission is to improve quality of life and mitigate climate change by transforming how people understand and manage plants, crops, forests, and vegetation in built environments.

Gevo specializes in producing renewable fuels and chemicals using sustainable resources. Its primary products include gasoline, jet fuel, diesel fuel, isobutanol, and renewable natural gas. The company aims to reduce greenhouse gas emissions by providing low-carbon alternatives to fossil fuels.