Theodorus

Theodorus is the venture capital arm of Université Libre de Bruxelles in Belgium, established in 2003. The firm specializes in seed and early-stage investments, focusing exclusively on spin-offs from the university. It targets sectors such as biotechnology, medical devices, engineering technologies, and high-tech applications. Theodorus primarily invests in the Walloon region of Belgium, allocating between €0.25 million and €2 million per company. Additionally, the firm has an office in Montreal, Canada, expanding its reach to early-stage projects based on proprietary disruptive technologies across both Canada and Europe.

Olivier Belenger

Founder, Managing Partner and Managing Director

Adrien Van der Borght

Investment Manager

Lotfi Yelles Chaouche

Partner

Patricia Escoffier

Investment Manager

Théo Risopoulos

General Partner

18 past transactions

Domain Therapeutics

Series A in 2022
Domain Therapeutics SA is a biopharmaceutical company based in Illkirch-Graffenstaden, France, focused on the discovery and early development of therapeutic drugs targeting G Protein-Coupled Receptors (GPCRs), which are key drug targets in various diseases. The company specializes in developing treatments for Central Nervous System (CNS) disorders and cancer. Utilizing its proprietary DTect-All technology, Domain Therapeutics identifies both orthosteric and allosteric ligands, including Silent Allosteric Modulators (SAMs), which are not discoverable through conventional methods. This innovative approach allows the company to address challenging GPCRs, including orphan and peptidic receptors. Founded in 2001, the company was previously known as Faust Pharmaceuticals SA before rebranding in December 2008.

DrugBank

Seed Round in 2022
DrugBank is a comprehensive online database that contains information on drugs and drug targets. They organize, collect, and curate all the important information about drugs into a single unified resource. It also combines detailed drug such as pharmacological, pharmaceutical, and chemical data with the comprehensive drug target sequence, structure, and pathway information. DrugBank is widely used by the drug industry, medicinal chemists, pharmacists, physicians, students, and the general public. It was founded in 2015 and is headquartered in Edmonton, AB, USA.

Cascador Health

Seed Round in 2022
Cascador Health operates a healthcare data platform designed to connect data providers with the research industry. The platform provides access to structured, validated, and anonymized real-world data, enabling healthcare providers and life science clients to gain valuable insights. This data assists in understanding therapeutic outcomes, improving site selection for clinical studies, monitoring safety and adverse effects, and optimizing hospital processes. By facilitating access to comprehensive data, Cascador Health aims to enhance healthcare delivery and support better patient care.

HypnoVR

Series A in 2021
HypnoVR SAS specializes in virtual reality-based medical hypnosis solutions aimed at managing pain and stress in patients. Founded in 2016 and based in Strasbourg, France, the company has developed a unique application that integrates virtual reality technology with medical hypnosis, effectively used in various medical fields, including pediatric surgery, gastroenterology, gynecology, and dental surgery. HypnoVR also focuses on research initiatives that explore the use of medical hypnosis in anesthesia to alleviate patients' stress and anxiety during medical procedures. In addition to its software solutions, the company offers specialized hardware designed for medical applications, catering to health professionals and institutions seeking innovative approaches to enhance patient care.

Kaspard

Series A in 2021
Kaspard is a Belgian company founded in 2017 that specializes in developing a non-intrusive sensory system aimed at enhancing the safety and well-being of elderly individuals in residential societies and nursing homes. The system is designed to monitor risk-related movements, such as when a patient gets out of bed or experiences a fall, while respecting their privacy. Kaspard's technology includes a small, contactless detection device that provides timely information and raises alarms at various levels, enabling staff to respond quickly and effectively to incidents involving residents. By improving monitoring capabilities, Kaspard seeks to enhance the quality of care for elderly individuals, ultimately contributing to better health outcomes in care facilities.

Giiant Pharma

Seed Round in 2021
Giiant Pharma is a preclinical-stage biotechnology company focused on developing innovative therapies for inflammatory bowel diseases (IBD). Utilizing its proprietary Precision Delivery technology platform, Giiant designs gut-restricted, tissue-specific small molecule drug therapeutics that target specific biological pathways in gastroenterology. The company's lead program, GT-2108, is a microbiota-activated PDE4 inhibitor prodrug, which aims to improve drug tolerability while enhancing therapeutic effects. By releasing its active form specifically in the colon, Giiant's approach allows for targeted treatment at the site of inflammation, potentially preventing the worsening of patients' conditions.

Classcraft

Venture Round in 2021
Classcraft Studios Inc. develops web and mobile applications designed for classroom behavior management through an innovative role-playing game format. Founded in 2013 and headquartered in Sherbrooke, Canada, Classcraft provides tools that enable teachers to effectively manage, motivate, and engage students by transforming traditional classroom dynamics into an interactive gaming experience. The platform is accessible on various operating systems, including Android, iOS, OS X, Chrome, and Windows, making it versatile for educational settings. By incorporating game mechanics into lessons, Classcraft aims to enhance student engagement and improve the overall learning experience.

Chromacure

Venture Round in 2018
ChromaCure will launch a drug development program to identify potential new candidates that selectively and potently inhibit cancer targets and potentially provide novel therapy for multiple forms of cancer, either as monotherapy or in combination with immunotherapy or chemotherapy.

Virteo

Series A in 2018
Virteo NV, founded in 2013 and headquartered in Mechelen, Belgium, operates a SaaS-based platform designed to recover unpaid invoices. The platform facilitates both internal dunning and external debt collection processes, catering to a diverse clientele that includes corporations, small and medium-sized enterprises, public institutions, court bailiffs, and lawyers. By providing tools that enable credit managers to collaborate directly with external partners, such as lawyers and recovery agencies, Virteo enhances efficiency and transparency in the debt collection process. The company emphasizes a socially responsible approach, allowing creditors to enforce ethical practices while achieving economic goals. Through its platform, Virteo empowers clients to reduce costs, improve recovery results, and maintain oversight of their external collection partners, fostering a more compliant and responsible debt recovery environment.

PharmaFluidics

Venture Round in 2018
Pharmafluidics is a spin-off company of the Vrije Universiteit Brussel, aiming at developing integrated milli- to nano-engineered solutions for mixing, separation and reaction processes. Rooted in chemical engineering with an advanced know-how in micro-fabrication technology, our team specializes in developing high quality and tailor-made solutions for any problem in the chemical and life sciences industry potentially benefiting from miniaturization or fine material structuring.

Acar'Up

Venture Round in 2017
AllerInvest develops and design a trap device designed to extract and kill the allergenic dust mites living in mattresses, chairs, carpets and other upholstered furniture.

X4C

Seed Round in 2016
X4C specializes in the development and application of monolayer chemical coating technology. This innovative approach enables the creation of thin, uniform coatings that enhance the properties of various substrates. The technology is designed to improve performance and durability in a range of industries, providing solutions that address specific material challenges. By focusing on the unique advantages of monolayer coatings, X4C aims to deliver significant improvements in functionality while maintaining cost-effectiveness for its clients.

Domobios

Seed Round in 2016
Domobios S.A., founded in 2013 and based in Brussels, Belgium, is engaged in the development, manufacturing, and sale of products designed to eradicate domestic pests, particularly focusing on allergens such as dust mites. The company produces a variety of items including insecticide sprays, traps, and detectors that target pests like house dust mites, lice, and bed bugs. One of its notable products is Acar’up, an easy-to-use device specifically designed to extract and kill allergenic dust mites from upholstered furniture. Domobios distributes its products through pharmacies, medical supply stores, and online platforms, catering to both domestic consumers and commercial entities such as hotels and pest control firms, with an emphasis on effective and environmentally friendly solutions.

Domobios

Seed Round in 2015
Domobios S.A., founded in 2013 and based in Brussels, Belgium, is engaged in the development, manufacturing, and sale of products designed to eradicate domestic pests, particularly focusing on allergens such as dust mites. The company produces a variety of items including insecticide sprays, traps, and detectors that target pests like house dust mites, lice, and bed bugs. One of its notable products is Acar’up, an easy-to-use device specifically designed to extract and kill allergenic dust mites from upholstered furniture. Domobios distributes its products through pharmacies, medical supply stores, and online platforms, catering to both domestic consumers and commercial entities such as hotels and pest control firms, with an emphasis on effective and environmentally friendly solutions.

Ovizio

Venture Round in 2015
Ovizio Imaging Systems NV/SA specializes in the development of digital holographic interferometric microscopy products, creating advanced 4D microscopic imaging devices and software. Founded in 2009 and headquartered in Brussels, Belgium, the company offers a range of devices, including the oLine 4D, which requires no specific sample preparation and compensates for sample imperfections; the iLine 4D, designed for various applications such as flow monitoring and cell culture observation; and various specialized instruments like ILine F for real-time monitoring of suspension cell cultures and iLine M for assessing cell confluence in multi-layer vessels. Ovizio also provides OsOne software for the visualization, analysis, and archiving of captured images, alongside QMod, which integrates holographic and fluorescence microscopy. Its products are widely utilized by scientists in pharmaceutical and biotechnology research and development, facilitating advancements in automated cell culture monitoring and analysis.

CluePoints

Series A in 2015
CluePoints INC designs and develops cloud-based risk-based quality management and monitoring software. The company offers its solutions to pharmaceutical companies and contract research organizations (CROs) to identify, visualize, manage, and document risks. The company was incorporated in 2012 and is based in King of Prussia, Pennsylvania. It has an additional office in Louvain-la-Neuve, Belgium.

neoScores

Series A in 2015
neoScores is a pioneer in offering digital music scores. It gives musicians the opportunity to simply and securely purchase scores or to use and to share notes with fellow musicians, anywhere they are. Gustaf is an OS and device independent web platform that allows the distribution of digital sheet music. High in quality, easy and flexible, beautiful and stylish, Gustaf allows to use scores via smartphone, tablet or computer through any operating system. That is how neoScores® wants to change the way sheet music is used by musicians. neoScores® was founded in July 2013 by Bart Van der Roost, Bob Hamblok and Jonas Coomans, three professional musicians with a passion for new media.

PharmaFluidics

Venture Round in 2014
Pharmafluidics is a spin-off company of the Vrije Universiteit Brussel, aiming at developing integrated milli- to nano-engineered solutions for mixing, separation and reaction processes. Rooted in chemical engineering with an advanced know-how in micro-fabrication technology, our team specializes in developing high quality and tailor-made solutions for any problem in the chemical and life sciences industry potentially benefiting from miniaturization or fine material structuring.
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