Theodorus III

Simmunome is a biotechnology company focused on enhancing the efficiency of clinical trial success through the use of artificial intelligence. The company develops advanced computational models that accurately represent the pathogenesis and immunogenesis of various diseases, particularly in oncology and the nervous system. By annotating cellular interactions at a comprehensive molecular level, Simmunome creates biologically representative models that aid in therapeutic and preventative drug discovery. The integration of machine learning and multi-omic data enhances the predictive accuracy of these models, allowing drug discovery and research organizations to better understand a drug's mechanism of action, target the right populations, and predict safety profiles.

Flare is a proactive digital footprint monitoring solution for organizations. Its AI-driven technology constantly scans the online world, including the dark, deep, and clear web, to discover unknown events, automatically prioritize risks, and deliver actionable intelligence you can use instantly to improve security.

Domain Therapeutics SA is a biopharmaceutical company based in Illkirch-Graffenstaden, France, focused on the discovery and early development of therapeutic drugs targeting G protein-coupled receptors (GPCRs), which are key drug targets in various diseases. Founded in 2001, the company specializes in developing small molecules for the treatment of central nervous system (CNS) disorders and cancer. It employs its proprietary technology platform, DTect-All, which enables the identification of orthosteric and allosteric ligands, including Silent Allosteric Modulators (SAMs) that are challenging to discover using conventional methods. In addition, Domain Therapeutics offers BioSens-All, a platform to explore the signaling complexities associated with GPCR activation, enhancing its ability to address difficult targets, such as orphan and peptidic GPCRs.

DrugBank is a developer of a comprehensive drug knowledge platform aimed at enhancing healthcare delivery and accelerating drug research. Its extensive database offers detailed information about drugs, their mechanisms of action, and interactions, which aids healthcare professionals in making informed decisions. The platform includes tools for drug search, interaction checking, allergy information, and drug labeling, facilitating precision medicine and clinical software applications. By integrating its knowledge base into various software solutions, DrugBank enables companies to leverage advanced insights and data science for drug discovery, helping to identify novel drug candidates and opportunities for drug repurposing. Additionally, DrugBank Online serves as a publicly available resource, offering limited datasets for academic and non-commercial researchers. With over 13,000 citations in academic publications, DrugBank is widely utilized by researchers and health professionals worldwide.

Cascador Health operates a healthcare data platform designed to connect data providers with the research industry. The platform provides access to structured, validated, and anonymized real-world data, enabling healthcare providers and life science clients to gain valuable insights. This data assists in understanding therapeutic outcomes, improving site selection for clinical studies, monitoring safety and adverse effects, and optimizing hospital processes. By facilitating access to comprehensive data, Cascador Health aims to enhance healthcare delivery and support better patient care.

Hypno VR SAS is a company that specializes in developing and operating virtual reality-based medical hypnosis solutions aimed at managing pain and stress. Founded in 2016 and headquartered in Strasbourg, France, Hypno VR creates applications designed to facilitate medical hypnosis during procedures, thereby reducing anxiety and discomfort for patients. The company's technology is particularly beneficial in various medical fields, including pediatric surgery, gastroenterology, gynecology, and dental surgery. In addition to its software solutions, Hypno VR also develops virtual reality hardware tailored for medical applications, catering to health professionals and institutions seeking innovative ways to enhance patient care.

Giiant Pharma is a preclinical-stage biotechnology company focused on developing innovative therapies for inflammatory bowel diseases (IBD). Utilizing its proprietary Precision Delivery technology platform, Giiant designs gut-restricted, tissue-specific small molecule drug therapeutics that target specific biological pathways in gastroenterology. The company's lead program, GT-2108, is a microbiota-activated PDE4 inhibitor prodrug, which aims to improve drug tolerability while enhancing therapeutic effects. By releasing its active form specifically in the colon, Giiant's approach allows for targeted treatment at the site of inflammation, potentially preventing the worsening of patients' conditions.

Classcraft is an online educational role-playing game designed to enhance classroom management and engagement for teachers. Founded by Lauren Young, Devin Young, Shawn Young, and Devin Young, the platform is accessible on multiple devices, including Android, iOS, OS X, Chrome, and Windows. Classcraft aims to transform the learning experience by motivating students through gamified elements that promote teamwork and personal growth. The platform encourages improved student behavior by allowing learners to earn rewards and powers that have real-world implications, fostering a playful yet effective educational environment.

ChromaCure is engaged in the development of innovative cancer therapies, focusing on discovering first-in-class small molecule therapeutics to address unmet needs in oncology. The company is initiating a drug development program aimed at identifying new candidates that selectively and potently inhibit cancer targets. This initiative seeks to provide novel treatment options for multiple forms of cancer, either as standalone therapies or in combination with existing immunotherapy or chemotherapy approaches. Through its efforts, ChromaCure aims to enhance the therapeutic landscape for cancer patients, offering potential new solutions for various cancer types.

VIRTEO NV, founded in 2013 and based in Mechelen, Belgium, operates a SaaS platform designed for the recovery of unpaid invoices. The platform addresses both internal dunning and external debt collection processes, catering to a diverse clientele that includes corporations, small and medium-sized enterprises, public institutions, court bailiffs, and lawyers. By facilitating direct collaboration between credit managers and external partners such as lawyers and recovery agencies, VIRTEO enhances efficiency, transparency, and compliance in debt collection. The company aims to reconcile the often negative perception of the debt collection industry with socially responsible practices, enabling creditors to recover debts while adhering to ethical standards. Through its platform, VIRTEO empowers customers to monitor, control, and enforce their corporate social responsibility policies, ultimately improving recovery outcomes and reducing costs.

PharmaFluidics is a spin-off from the Vrije Universiteit Brussel that specializes in developing innovative micro-chip-based chromatography columns for applications in biomarker detection, diagnostics, and drug research and development. The company focuses on creating integrated milli- to nano-engineered solutions tailored for mixing, separation, and reaction processes, leveraging its expertise in chemical engineering and micro-fabrication technology. By providing high-quality, custom solutions, PharmaFluidics aims to enhance the sensitivity and accuracy of detecting active compounds in complex biological samples, including biopsies and proteome digests. This approach supports researchers in their efforts to achieve more effective analytical separations, ultimately benefiting the chemical and life sciences industries.

Acar'Up develops and design a trap device designed to extract and kill the allergenic dust mites living in mattresses, chairs, carpets and other upholstered furniture.

X4C specializes in developing advanced molecular coatings for life science applications, focusing on in vitro diagnostics. The company utilizes innovative monolayer chemical coating technology to create robust organic monolayers that can be easily modified, allowing for enhanced functionality of various substrates. Their product offerings include nanoparticles and calixarenes, along with custom services tailored to meet specific industry needs. X4C's coatings are designed for a range of applications, including diagnostics, medical devices, electronics, and optics, ensuring that healthcare professionals can maintain the inherent properties of materials while enhancing their performance.

Domobios specializes in developing innovative pest control solutions, primarily focusing on the eradication of domestic pests such as dust mites, lice, and bed bugs. The company's flagship product, Acar’up, is a user-friendly trap designed to effectively extract and eliminate allergenic dust mites from various surfaces, including mattresses, chairs, and carpets. In addition to Acar’up, Domobios offers a range of other pest management devices, including detectors that replicate the typical habitats of bedbugs, cockroach traps, and sprays for controlling dog mites. These products cater to diverse clients, including hotels, pest control companies, breeders, and homeowners, helping them enhance their living environments and improve overall quality of life through effective and eco-friendly solutions.

Domobios specializes in developing innovative pest control solutions, primarily focusing on the eradication of domestic pests such as dust mites, lice, and bed bugs. The company's flagship product, Acar’up, is a user-friendly trap designed to effectively extract and eliminate allergenic dust mites from various surfaces, including mattresses, chairs, and carpets. In addition to Acar’up, Domobios offers a range of other pest management devices, including detectors that replicate the typical habitats of bedbugs, cockroach traps, and sprays for controlling dog mites. These products cater to diverse clients, including hotels, pest control companies, breeders, and homeowners, helping them enhance their living environments and improve overall quality of life through effective and eco-friendly solutions.

Ovizio specializes in digital holographic interferometric microscopy, creating advanced 4D microscopic imaging devices and associated software. The company targets scientists and biomanufacturers by offering automated cell culture monitoring and analysis systems that enhance the scaling of cell culture processes. Its technology is primarily aimed at the life sciences sector, specifically in bioprocessing and research and development. By utilizing digital holographic microscopy, Ovizio provides innovative solutions that support the growth and efficiency of scientific operations.

CluePoints Inc. is a company that specializes in developing cloud-based software for risk-based quality management and monitoring, primarily serving pharmaceutical companies and contract research organizations (CROs). Founded in 2012 and headquartered in King of Prussia, Pennsylvania, with an additional office in Louvain-la-Neuve, Belgium, CluePoints offers solutions designed to identify, visualize, manage, and document risks associated with clinical trials. Its flagship product utilizes advanced statistical algorithms to assess the quality, accuracy, and integrity of clinical trial data both during and after studies. By adhering to guidelines from regulatory bodies such as the ICH, FDA, and EMA, CluePoints supports traditional on-site monitoring and medical reviews while driving effective risk-based monitoring strategies. The software is notable for its ability to detect anomalous data and site errors, ultimately enhancing clinical data quality, optimizing on-site monitoring efforts, and reducing the risks associated with regulatory submissions.

neoScores is an innovative company based in Kontich, Belgium, that specializes in providing an online platform for purchasing and playing digital sheet music. Established in 2013 by three professional musicians—Bart Van der Roost, Bob Hamblok, and Jonas Coomans—the company aims to transform the way musicians access and utilize sheet music. The platform, known as Gustaf, is compatible across various operating systems and devices, enabling users to securely buy scores and share notes with fellow musicians from anywhere. With a focus on high-quality, flexible, and aesthetically pleasing digital scores, neoScores strives to enhance the musical experience for users, allowing them to engage with music seamlessly via smartphones, tablets, or computers.

PharmaFluidics is a spin-off from the Vrije Universiteit Brussel that specializes in developing innovative micro-chip-based chromatography columns for applications in biomarker detection, diagnostics, and drug research and development. The company focuses on creating integrated milli- to nano-engineered solutions tailored for mixing, separation, and reaction processes, leveraging its expertise in chemical engineering and micro-fabrication technology. By providing high-quality, custom solutions, PharmaFluidics aims to enhance the sensitivity and accuracy of detecting active compounds in complex biological samples, including biopsies and proteome digests. This approach supports researchers in their efforts to achieve more effective analytical separations, ultimately benefiting the chemical and life sciences industries.