iPronics develops optical networking hardware and software that enables programmable, software-defined photonics for data-center and AI workloads. The company offers a general-purpose integrated programmable photonic system that allows optical hardware to be configured through software to perform multiple functions. This optical reconfigurability supports applications such as data-center interconnection, artificial intelligence, signal processing, sensing, and quantum information, enabling businesses to apply the same hardware across diverse computational tasks. The technology facilitates seamless AI cluster communication and aims to future-proof data-center infrastructure by providing flexible, high-performance photonic capabilities.
Teleo specializes in transforming existing heavy machinery into remote-controlled robots, allowing operators to control equipment from a significant distance. By retrofitting current fleets with its advanced supervised autonomy technology, Teleo enables operators to seamlessly switch between machines and job sites, enhancing both productivity and safety. The company's approach allows machine operators to work from remote operation centers rather than being confined to the equipment's cabin, ultimately improving operational efficiency and providing valuable insights into job site conditions.
Founded in 2017 by Dr. Matthew Hill, Elegen is a biotechnology company specializing in microfluidic technology for the development of advanced DNA synthesizers. Its mission is to accelerate biomedical progress through innovative synthetic biology solutions.
Toposware
Seed Round in 2023
Toposware Inc. is a technology company that develops a privacy-focused blockchain platform aimed at government agencies, businesses, and individuals seeking advanced data security. Founded in 2019, the company is headquartered in Boston, Massachusetts, and is comprised of a diverse team of computer scientists, cryptographers, and engineers. Toposware's platform features an interoperable blockchain ecosystem that employs zero-knowledge proofs, allowing for anonymous transactions of coins and messages. Unlike traditional blockchain systems that rely on proof-of-work mechanisms, Toposware utilizes a proof-of-stake approach, which enhances efficiency by reducing the computational power required for network operations, thereby lowering transaction fees and saving time for its clients.
Betteromics
Series A in 2023
Betteromics is a SaaS platform empowering life sciences professionals with AI-driven computational techniques. It integrates seamlessly within clients' Virtual Private Clouds, connecting diverse data sources and providing a centralized, objective data hub. The platform accelerates precision biomarker discovery and clinical research by managing large, complex molecular datasets securely.
Lyten is an advanced materials company focused on low-carbon solutions. It converts methane-derived carbon into a tunable 3D graphene material that underpins decarbonization applications. The company develops lithium-sulfur battery technology aimed at automotive, aerospace, and defense sectors, seeking higher energy density, longer range, faster charging, and improved safety while reducing carbon footprint. It is also developing a polymer composite that can reduce plastic usage by about 50% without compromising structural integrity or impact resistance. Additionally, Lyten is advancing next-generation sensors with enhanced sensitivity and selectivity for automotive, industrial, health, and safety applications.
Chemify specializes in developing a chemical digitization platform designed to facilitate drug and materials discovery as well as chemical synthesis. The company's innovative approach involves using automated synthetic hardware combined with digital XDL code to convert code into molecules on demand. This system is modular, universal, scalable, and teachable, making it highly versatile for various applications in chemical and material research. Chemify's software includes a unique chemical programming language and natural language recognition capabilities that translate synthetic procedures efficiently. Additionally, the platform features a comprehensive ontology that provides detailed insights into reaction conditions and flags potential issues, offering scientists real-time telemetry of reactions.
ArsenalBio
Series B in 2022
ArsenalBio is a programmable cell therapy company established in 2019, focused on developing and commercializing innovative immune cell therapies, particularly for cancer treatment. The company utilizes advanced technologies, including CRISPR-based genome engineering, synthetic biology, and machine learning, to create multifunctional T-cell therapies. ArsenalBio's approach involves the precise insertion of large synthetic DNA sequences, enabling the generation of next-generation autologous T-cell therapies. By integrating these cutting-edge methods, ArsenalBio aims to enhance the effectiveness and safety of immune cell therapies, reduce costs for healthcare providers, and improve market access, ultimately broadening patient outcomes and making these therapies more widely available.
Manifold Bio
Series A in 2022
Manifold Biotechnologies, Inc. is a biotechnology company that specializes in developing platforms for the pharmacological measurement of various therapeutic protein variants. By integrating DNA technologies with machine learning, the company aims to create protein drugs that address challenging diseases. Manifold Bio's innovative approach includes a protein barcoding platform designed to enable multiplexed quantitation of protein therapeutics, thereby generating extensive data that enhances the drug development process. Founded in 2019 and located in Allston, Massachusetts, the company is focused on advancing measurement-driven design in the field of protein therapeutics.
Toposware
Seed Round in 2019
Toposware Inc. is a technology company that develops a privacy-focused blockchain platform aimed at government agencies, businesses, and individuals seeking advanced data security. Founded in 2019, the company is headquartered in Boston, Massachusetts, and is comprised of a diverse team of computer scientists, cryptographers, and engineers. Toposware's platform features an interoperable blockchain ecosystem that employs zero-knowledge proofs, allowing for anonymous transactions of coins and messages. Unlike traditional blockchain systems that rely on proof-of-work mechanisms, Toposware utilizes a proof-of-stake approach, which enhances efficiency by reducing the computational power required for network operations, thereby lowering transaction fees and saving time for its clients.
Chalk is a data platform that empowers machine learning and generative AI. It enables data teams to declare features and dependencies using idiomatic Python, which are then compiled into parallel pipelines running on a Rust-based engine. This ensures temporally consistent training sets for data scientists and live feature values for models, reducing development time significantly.