Vertical Group

MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases with a focus on vagus nerve stimulation (VNS). Its first commercial product, Vivistim, is FDA approved for ischemic stroke survivors with moderate to severe upper limb impairment six months or more after their stroke.

Provider of medical technology for spine surgery. The company’s proprietary aprevo™ digital-to-device 3-D printed implant system for spine is first-ever surgical implant to be designated by the FDA as a breakthrough technology. Hospital and surgeon customers across the country choose aprevo™ for the benefits of personalized medicine in lumbar fusion surgery. Carlsmed was founded in 2018 and is headquartered in San Diego, California.

Route 92 Medical is a developer of a stealthy catheter for stroke treatment. The company was founded in 2015 and based in San Mateo, California.

Provider of medical technology for spine surgery. The company’s proprietary aprevo™ digital-to-device 3-D printed implant system for spine is first-ever surgical implant to be designated by the FDA as a breakthrough technology. Hospital and surgeon customers across the country choose aprevo™ for the benefits of personalized medicine in lumbar fusion surgery. Carlsmed was founded in 2018 and is headquartered in San Diego, California.

Biorez is a medical device company whose aim is to apply its patented and proprietary technology comprised of PLLA, a degradable polymer, in orthopedic implant devices for regeneration and augmentation of soft tissue. In addition to the L-C Ligament®, Biorez has also developed a suite of associated products, including the biorez GRAFT™, a FDA 510(k)-cleared innovative device for soft tissue augmentation of the rotator cuff in the United States.

Biorez is a medical device company whose aim is to apply its patented and proprietary technology comprised of PLLA, a degradable polymer, in orthopedic implant devices for regeneration and augmentation of soft tissue. In addition to the L-C Ligament®, Biorez has also developed a suite of associated products, including the biorez GRAFT™, a FDA 510(k)-cleared innovative device for soft tissue augmentation of the rotator cuff in the United States.

One in two people experience debilitating back, neck, shoulder, or joint pain — but traditional treatments have failed to meet their needs. Physical therapy can be expensive and hard to access; appointments often involve long commutes and missed work. Making matters worse, unresolved pain can trigger the overuse of opioids and surgeries. We’re making high-quality care accessible by pairing wearable sensors and computer vision with a world-class clinical team. Hinge Health puts a digital clinic in every member's pocket. Now millions of people can access personalized digital care from a physical therapist, guidance on behavior change from a health coach, and expert consultations with an orthopedic surgeon. With a single app and wearable technology like our Enso device, we’re helping empower people to move beyond pain.

Silk Road Medical is a medical company that provides medical devices and solutions for treating vascular diseases. The company develops and manufactures less-invasive medical devices to improve the treatment of carotid artery disease through proprietary trans-carotid therapies.

Outset Medical is a medical tech company that manufactures medical equipment. They provide reimagining dialysis for patients and health care providers. Their system comes equipped with wireless data, sensor-based automation, and an animated touchscreen to make the systems.

One in two people experience debilitating back, neck, shoulder, or joint pain — but traditional treatments have failed to meet their needs. Physical therapy can be expensive and hard to access; appointments often involve long commutes and missed work. Making matters worse, unresolved pain can trigger the overuse of opioids and surgeries. We’re making high-quality care accessible by pairing wearable sensors and computer vision with a world-class clinical team. Hinge Health puts a digital clinic in every member's pocket. Now millions of people can access personalized digital care from a physical therapist, guidance on behavior change from a health coach, and expert consultations with an orthopedic surgeon. With a single app and wearable technology like our Enso device, we’re helping empower people to move beyond pain.

Route 92 Medical is a developer of a stealthy catheter for stroke treatment. The company was founded in 2015 and based in San Mateo, California.

Suture Concepts provides solutions for physicians who practice in a cost-conscious environment. They also provide solutions for securing soft tissue to other tissues, the bone, or medical devices.

Silk Road Medical is a medical company that provides medical devices and solutions for treating vascular diseases. The company develops and manufactures less-invasive medical devices to improve the treatment of carotid artery disease through proprietary trans-carotid therapies.

Outset Medical is a medical tech company that manufactures medical equipment. They provide reimagining dialysis for patients and health care providers. Their system comes equipped with wireless data, sensor-based automation, and an animated touchscreen to make the systems.

Outset Medical is a medical tech company that manufactures medical equipment. They provide reimagining dialysis for patients and health care providers. Their system comes equipped with wireless data, sensor-based automation, and an animated touchscreen to make the systems.

Suture Concepts provides solutions for physicians who practice in a cost-conscious environment. They also provide solutions for securing soft tissue to other tissues, the bone, or medical devices.

Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer. It is a private equity-backed neurosurgical company focused solely on diseases of the brain. It develops MRI-guided, laser-based systems designed for the ablation of brain lesions. The company's system applies focused laser energy to ablate brain tumors from the inside, with little or no effect on surrounding healthy tissue as well as provides clinicians a new neurosurgical tool that offers real-time control and visualization of the therapy during laser ablation treatment, enabling neurosurgeons to ablate (treat with lethal heat) brain lesions and brain tumors that may be difficult to approach via traditional methods. It was founded in 1999 and has offices in Minneapolis, Minnesota, USA and Winnipeg, Manitoba, Canada.

Omada Health is a digital care company that offers innovative and clinically effective digital health programs to empower individuals to engage in their health and lead healthier lives. The program is personalized to meet each participant’s unique needs as they evolve, ranging from diabetes prevention, type 2 diabetes management, hypertension, behavioral health, and musculoskeletal issues. Omada combines professional health coaching, connected health devices, real-time data, and personalized feedback to deliver clinically meaningful results. The company is the largest CDC-recognized provider of the National Diabetes Prevention Program.

AtheroMed, Inc. develops treatments for peripheral arterial disease. The company was incorporated in 2006 and is headquartered in Menlo Park, California.

Omada Health is a digital care company that offers innovative and clinically effective digital health programs to empower individuals to engage in their health and lead healthier lives. The program is personalized to meet each participant’s unique needs as they evolve, ranging from diabetes prevention, type 2 diabetes management, hypertension, behavioral health, and musculoskeletal issues. Omada combines professional health coaching, connected health devices, real-time data, and personalized feedback to deliver clinically meaningful results. The company is the largest CDC-recognized provider of the National Diabetes Prevention Program.

Silk Road Medical is a medical company that provides medical devices and solutions for treating vascular diseases. The company develops and manufactures less-invasive medical devices to improve the treatment of carotid artery disease through proprietary trans-carotid therapies.

AtheroMed, Inc. develops treatments for peripheral arterial disease. The company was incorporated in 2006 and is headquartered in Menlo Park, California.

Flexuspine operates as a spine company. It offers a spinal segment replacement to provide an alternative to lumbar fusion by re-establishing mobility to an affected segment of the lumbar spine. The company’s functional spinal unit is a comprehensive device composed of an interbody disc component and posterior dynamic resistance component to replace the natural kinematics of the motion segment. Flexuspine was founded on 2003 and is based in Pittsburgh, Pennsylvania.

Suture Concepts provides solutions for physicians who practice in a cost-conscious environment. They also provide solutions for securing soft tissue to other tissues, the bone, or medical devices.

TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. Its Necrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

Alpha Innotech Corp. manufactures and sells analytical laboratory instruments, software, and consumables used in life science research laboratories for the study of nucleic acids, proteins, and cells worldwide. Products The company's imaging systems, sold under its trademarks AlphaDigiDoc, AlphaImager, FluorChem and red, comprise a digital camera and bench-top dark enclosure and are used to detect, archive, and analyze fluorescent, chemiluminescent and visible signals from biological samples, such as DNA, proteins and bacterial colonies. Alpha Innotech Corp. was founded in 1992.

TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. Its Necrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

At ENTrigue Surgical, we're rethinking established Otolaryngology techniques to develop innovative instruments, materials, and medical devices that make sinus surgery more efficient, effective, and comfortable for patients.

PhotoThera is currently hiring for the following positions: Sr. Software Engineer Mechanical Engineer Configuration Management Engineer Sr. Electrical Engineer Send your resume and cover letter to ktitano@photothera.com, or go to www.photothera.com for further information. Specialties laser, medical device, eschemic, stroke, infrared

Alpha Innotech Corp. manufactures and sells analytical laboratory instruments, software, and consumables used in life science research laboratories for the study of nucleic acids, proteins, and cells worldwide. Products The company's imaging systems, sold under its trademarks AlphaDigiDoc, AlphaImager, FluorChem and red, comprise a digital camera and bench-top dark enclosure and are used to detect, archive, and analyze fluorescent, chemiluminescent and visible signals from biological samples, such as DNA, proteins and bacterial colonies. Alpha Innotech Corp. was founded in 1992.

OncoMed Pharmaceuticals is a biotechnology company dedicated to improving cancer treatment, by developing monoclonal antibodies that target the biologic pathways critical to tumor initiating cells, also known as “cancer stem cells”. They are leveraging their understanding of these tumor initiating cells to discover and develop novel therapeutics that could provide important alternatives for the treatment of cancer.

ForteBio is a venture-capital funded life science company developing analytical systems to provide rapid, real-time results for protein quantification or characterization of protein-protein interaction. These systems enable real-time analysis of biomolecular interactions in micro-volume sample sizes, providing information on affinity, kinetics, and concentration.

Onyx Pharmaceuticals (NASDAQ: ONXX) is a biopharmaceutical company engaged in the development and commercialization of innovative therapies for improving the lives of people with cancer and other serious diseases.

Meritage Pharma, Inc. develops prescription products for the treatment of gastrointestinal and atopic diseases. It offers budesonide, an active pharmaceutical ingredient and a glucocorticoid steroid for products that treat pediatric asthma, allergic rhinitis, and Crohn’s disease; and oral budesonide suspension, an oral formulation of budesonide for the potential treatment of adolescents and young adults with eosinophilic esophagitis, an allergic inflammation of the gastrointestinal tract. Meritage Pharma, Inc. was founded in 2008 and is based in San Diego, California.

Tepha is a medical device firm pursuing the development and commercialization of innovative products based on the company's proprietary biomaterial technology. The technology provides a new class of absorbable biomaterials, known as polyhydroxyalkanoates , which may be tailored to meet unmet needs for medical devices in multiple fields. Tepha's novel, biosynthetically produced materials offer superior performance in flexibility, elasticity, and biocompatibility; and, for its fiber-based products, excellent tensile strength and strength retention.

BioSurface Engineering Technologies, Inc., also known as BioSET, engages in developing proprietary therapeutic peptides as medical devices to improve bone and soft tissue repair. The company focuses on developing devices for orthobiologics applications. Its products include AMPLEX, an implantable combination device of the B2A peptide and a synthetic ceramic scaffold for use as a surgical bone graft implant for lumbar degenerative disc disease, as well as for use in spine, cervical spine, and foot and ankle fusion surgeries. The company also develops products for sports medicine applications based on its F2A peptide; and peptide signaling molecules and various scaffold biomaterials for use in musculoskeletal applications, including trauma, fracture repair, and other soft tissue treatments. BioSurface Engineering Technologies, Inc. was founded in 2001 and is based in Rockville, Maryland.

Silk Road Medical is a medical company that provides medical devices and solutions for treating vascular diseases. The company develops and manufactures less-invasive medical devices to improve the treatment of carotid artery disease through proprietary trans-carotid therapies.

Bacchus Vascular, Inc. offers medical devices for the treatment of occlusive vascular disease to interventional radiologists and vascular surgeons in the United States. It provides the TRELLIS-8 Peripheral Infusion System, an isolated thrombolysis catheter that enables treatment of deep vein thrombosis and arterial occlusions by targeted delivery of clot-dissolving drugs. The company was founded in 1999 and is based in Santa Clara, California.

PhyFlex Networks is a business services software and broadband access company that creates new business models for cable operators through its True Broadband solution. True Broadband includes a comprehensive software suite for the creation, provisioning, and management of end-to-end broadband services dynamically and on demand.

Elron Ventures is an early-stage investor committed to turning promising ideas into global industry leaders, with a proven track record of investments and successful M&As worldwide. Elron invests in cyber security and B2B software. Since its establishment in 1962, Elron stands on the forefront of Israeli innovation both as a founder and early investor in companies across various industries such as Elbit, Medingo, Given Imaging, Cloudyn, Cyber Secdo, and Alcide.

Galil Medical is a new era of minimally invasive cryotherapy solutions that enhance patient quality of life. Galil Medical’s technology involves freezing and ablating diseased tissue in a technique referred to as cryotherapy, also referred to as cryoablation and cryosurgery. Galil Medical cryotherapy systems use compressed Argon gas to produce extremely low temperatures. As the gas passes through the cryoablation needle, the tip of the needle is cooled, forming an iceball, which engulfs the tumor and destroys the tissue. A variety of needle types is available to sculpt a freeze zone conformed to the tumor size and shape. Galil Medical cryosurgical systems precisely deliver sub-zero temperatures to target tissue with the aid of patented 17-gauge cryoablation needles and high-resolution imaging for the cryosurgical ablation of benign and cancerous tumors. Cryotherapy ablation has been widely used for prostate cancer treatment and kidney cancer treatment. New ablation treatments for various other tumors are being developed in the Women’s Health and Interventional Radiology markets.

TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. Its Necrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

ViaCyte is a preclinical therapeutic company specializing in regenerative medicine therapies for diabetes. Their therapy is based on the differentiation of stem cells into pancreatic beta-cell precursors, with subcutaneous implantation in an encapsulation device. Data in their publications demonstrate that these cells can produce therapeutically relevant levels of insulin in response to blood glucose, and sustain diabetic animals. Their goal is a product which can free both Type 1 and Type 2 patients with diabetes from insulin dependence on a long-term basis, while reducing or eliminating hypoglycemic, microvasculature, and weight-related cardiovascular complications.

Suture Concepts provides solutions for physicians who practice in a cost-conscious environment. They also provide solutions for securing soft tissue to other tissues, the bone, or medical devices.

PhotoThera is currently hiring for the following positions: Sr. Software Engineer Mechanical Engineer Configuration Management Engineer Sr. Electrical Engineer Send your resume and cover letter to ktitano@photothera.com, or go to www.photothera.com for further information. Specialties laser, medical device, eschemic, stroke, infrared

Bayhill Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing therapeutics for autoimmune diseases. The company uses its therapeutic BHT-DNA platform to develop a pipeline of treatment candidates for autoimmune diseases. Its products in clinical pipeline include BHT-3021, which is in Phase I/II clinical trial for reducing or eliminating the immune system’s attack on the pancreas; BHT-3009, which completed its Phase II trial for the treatment of multiple sclerosis; and BHT-3034, which is in preclinical studies for the treatment of myasthenia gravis. The company was formerly known as Tolerion, Inc. and changed its name to Bayhill Therapeutics, Inc. in November 2002. Bayhill Therapeutics, Inc. was founded in 2000 and is headquartered in Palo Alto, California.

Alpha Innotech Corp. manufactures and sells analytical laboratory instruments, software, and consumables used in life science research laboratories for the study of nucleic acids, proteins, and cells worldwide. Products The company's imaging systems, sold under its trademarks AlphaDigiDoc, AlphaImager, FluorChem and red, comprise a digital camera and bench-top dark enclosure and are used to detect, archive, and analyze fluorescent, chemiluminescent and visible signals from biological samples, such as DNA, proteins and bacterial colonies. Alpha Innotech Corp. was founded in 1992.

ForteBio is a venture-capital funded life science company developing analytical systems to provide rapid, real-time results for protein quantification or characterization of protein-protein interaction. These systems enable real-time analysis of biomolecular interactions in micro-volume sample sizes, providing information on affinity, kinetics, and concentration.

PhotoThera is currently hiring for the following positions: Sr. Software Engineer Mechanical Engineer Configuration Management Engineer Sr. Electrical Engineer Send your resume and cover letter to ktitano@photothera.com, or go to www.photothera.com for further information. Specialties laser, medical device, eschemic, stroke, infrared

OncoMed Pharmaceuticals is a biotechnology company dedicated to improving cancer treatment, by developing monoclonal antibodies that target the biologic pathways critical to tumor initiating cells, also known as “cancer stem cells”. They are leveraging their understanding of these tumor initiating cells to discover and develop novel therapeutics that could provide important alternatives for the treatment of cancer.

Bayhill Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing therapeutics for autoimmune diseases. The company uses its therapeutic BHT-DNA platform to develop a pipeline of treatment candidates for autoimmune diseases. Its products in clinical pipeline include BHT-3021, which is in Phase I/II clinical trial for reducing or eliminating the immune system’s attack on the pancreas; BHT-3009, which completed its Phase II trial for the treatment of multiple sclerosis; and BHT-3034, which is in preclinical studies for the treatment of myasthenia gravis. The company was formerly known as Tolerion, Inc. and changed its name to Bayhill Therapeutics, Inc. in November 2002. Bayhill Therapeutics, Inc. was founded in 2000 and is headquartered in Palo Alto, California.

Velocimed was founded by a group of well known medical entrepreneurs. The company's founders envisioned a company that would become a global leader in the identification and development of innovative technologies with the power to improve the lives of patients whose clinical needs are not being met. Lead by a seasoned management team, Velocimed creates products internally and also looks externally for new technologies by partnering with physicians, inventors and institutions -- particularly those who may lack access to the necessary resources required for early development of new ideas. At Velocimed, they believe that they own a unique position in medical innovation and commercialization. Unlike small incubators, they have the expertise to commercialize viable technology. And unlike large companies, they have the ability to pinpoint opportunities faster and move more quickly.

Vascular Architects, Inc. designs, develops, manufactures and markets devices used in the treatment of vascular stenoses, occlusions and non-vascular obstructions. A key area of emphasis is the treatment of peripheral vascular disease, which manifests itself as a reduction or loss of blood flow due to the narrowing or closing of arteries. Vascular Architects was founded in October 1997 by Thomas J. Fogarty, M.D. Dr Fogarty is an internationally renowned surgeon, professor, inventor and entrepreneur who has founded or cofounded more than 25 start-up companies that develop innovative medical devices. He has authored or coauthored over 150 professional articles, is a member of 29 professional societies, and is an inventor on more than 65 U.S. patents. Their founder and management team form a highly experienced group of technical, clinical and business personnel. Key opinion leaders in the interventional and vascular surgery communities have been recruited to serve on the Vascular Architects' Scientific Advisory Board.

BioSurface Engineering Technologies, Inc., also known as BioSET, engages in developing proprietary therapeutic peptides as medical devices to improve bone and soft tissue repair. The company focuses on developing devices for orthobiologics applications. Its products include AMPLEX, an implantable combination device of the B2A peptide and a synthetic ceramic scaffold for use as a surgical bone graft implant for lumbar degenerative disc disease, as well as for use in spine, cervical spine, and foot and ankle fusion surgeries. The company also develops products for sports medicine applications based on its F2A peptide; and peptide signaling molecules and various scaffold biomaterials for use in musculoskeletal applications, including trauma, fracture repair, and other soft tissue treatments. BioSurface Engineering Technologies, Inc. was founded in 2001 and is based in Rockville, Maryland.

PhyFlex Networks is a business services software and broadband access company that creates new business models for cable operators through its True Broadband solution. True Broadband includes a comprehensive software suite for the creation, provisioning, and management of end-to-end broadband services dynamically and on demand.

Bayhill Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing therapeutics for autoimmune diseases. The company uses its therapeutic BHT-DNA platform to develop a pipeline of treatment candidates for autoimmune diseases. Its products in clinical pipeline include BHT-3021, which is in Phase I/II clinical trial for reducing or eliminating the immune system’s attack on the pancreas; BHT-3009, which completed its Phase II trial for the treatment of multiple sclerosis; and BHT-3034, which is in preclinical studies for the treatment of myasthenia gravis. The company was formerly known as Tolerion, Inc. and changed its name to Bayhill Therapeutics, Inc. in November 2002. Bayhill Therapeutics, Inc. was founded in 2000 and is headquartered in Palo Alto, California.

OsteoBiologics is a biotechnology company. It engages in the development and manufacture of bio-absorbable polymeric scaffolds, films, and related instrumentations for the repair and replacement of bone, soft tissue, and articular cartilage. It provides ACTAEON, a tissue evaluation system, which determines the degree and scope of articular cartilage degeneration. It also manufactures custom parts. OsteoBiologics was founded in 1993 and is headquartered in San Antonio, Texas.

Bacchus Vascular, Inc. offers medical devices for the treatment of occlusive vascular disease to interventional radiologists and vascular surgeons in the United States. It provides the TRELLIS-8 Peripheral Infusion System, an isolated thrombolysis catheter that enables treatment of deep vein thrombosis and arterial occlusions by targeted delivery of clot-dissolving drugs. The company was founded in 1999 and is based in Santa Clara, California.

Velocimed was founded by a group of well known medical entrepreneurs. The company's founders envisioned a company that would become a global leader in the identification and development of innovative technologies with the power to improve the lives of patients whose clinical needs are not being met. Lead by a seasoned management team, Velocimed creates products internally and also looks externally for new technologies by partnering with physicians, inventors and institutions -- particularly those who may lack access to the necessary resources required for early development of new ideas. At Velocimed, they believe that they own a unique position in medical innovation and commercialization. Unlike small incubators, they have the expertise to commercialize viable technology. And unlike large companies, they have the ability to pinpoint opportunities faster and move more quickly.

Vascular Architects, Inc. designs, develops, manufactures and markets devices used in the treatment of vascular stenoses, occlusions and non-vascular obstructions. A key area of emphasis is the treatment of peripheral vascular disease, which manifests itself as a reduction or loss of blood flow due to the narrowing or closing of arteries. Vascular Architects was founded in October 1997 by Thomas J. Fogarty, M.D. Dr Fogarty is an internationally renowned surgeon, professor, inventor and entrepreneur who has founded or cofounded more than 25 start-up companies that develop innovative medical devices. He has authored or coauthored over 150 professional articles, is a member of 29 professional societies, and is an inventor on more than 65 U.S. patents. Their founder and management team form a highly experienced group of technical, clinical and business personnel. Key opinion leaders in the interventional and vascular surgery communities have been recruited to serve on the Vascular Architects' Scientific Advisory Board.

PhyFlex Networks is a business services software and broadband access company that creates new business models for cable operators through its True Broadband solution. True Broadband includes a comprehensive software suite for the creation, provisioning, and management of end-to-end broadband services dynamically and on demand.

BioSurface Engineering Technologies, Inc., also known as BioSET, engages in developing proprietary therapeutic peptides as medical devices to improve bone and soft tissue repair. The company focuses on developing devices for orthobiologics applications. Its products include AMPLEX, an implantable combination device of the B2A peptide and a synthetic ceramic scaffold for use as a surgical bone graft implant for lumbar degenerative disc disease, as well as for use in spine, cervical spine, and foot and ankle fusion surgeries. The company also develops products for sports medicine applications based on its F2A peptide; and peptide signaling molecules and various scaffold biomaterials for use in musculoskeletal applications, including trauma, fracture repair, and other soft tissue treatments. BioSurface Engineering Technologies, Inc. was founded in 2001 and is based in Rockville, Maryland.

CardioThoracic Systems designs, develops, and manufactures surgical products and systems for minimally invasive cardiac surgery. The Company's current products are designed to enable the majority of cardiothoracic surgeons, using their existing skills coupled with company-sponsored training, to perform MICS on a beating heart. The OPCAB (Off Pump Coronary Artery Bypass) and MIDCAB (Minimally Invasive Direct Coronary Artery Bypass) procedures eliminate the need for a heart-lung machine, and recent studies indicate that the MICS procedures reduce the trauma, procedural costs and post-surgical complications associated with conventional coronary artery bypass graft (CABG) surgery while providing long-term procedural success rates comparable to CABG surgery. CardioThoracic Systems was founded in 1994 and is based in Cupertino, California. As of November 15, 1999, CardioThoracic Systems, Inc. was acquired by Guidant Corp.