Viscogliosi Brothers

Spine BioPharma develops a non-surgical solution for back pain that will eliminate pain and restore functionality, without the use of opioids. The company's pipeline of therapeutic treatments targets the clinical benefits of reducing pain, restoring function and slowing or stopping pathological disease progression. Its mission is to improve the lives of millions of individuals suffering every day from degenerative spine diseases by delivering clinically proven, safe, and effective therapies that inhibit pain and inflammation, and restores quality of life.

Companion Spine provides interventional therapies and technologies to ensure back pain is resolved with minimal disruption, less pain, and Safer to people's quality of life.

Spine BioPharma develops a non-surgical solution for back pain that will eliminate pain and restore functionality, without the use of opioids. The company's pipeline of therapeutic treatments targets the clinical benefits of reducing pain, restoring function and slowing or stopping pathological disease progression. Its mission is to improve the lives of millions of individuals suffering every day from degenerative spine diseases by delivering clinically proven, safe, and effective therapies that inhibit pain and inflammation, and restores quality of life.

Small Bones Innovations (SBi) makes devices for small bones and joints, particularly focusing on trauma and arthroplasty.

Small Bone Innovations (SBi) specializes in the development and manufacturing of medical devices aimed at small bones and joints, with a particular emphasis on trauma and arthroplasty. The company provides a range of implants designed for various anatomical areas, including the thumb, hand, wrist, elbow, foot, and ankle. Its product offerings include implants specifically designed to treat basal joint arthritis and those intended for replacing anatomic joint surfaces. SBi's innovations focus on preserving bone structure and minimizing disruption to collateral ligament origins and insertions, as well as soft skeletal implants, thereby enhancing surgical outcomes for patients with joint-related conditions.

Small Bones Innovations (SBi) makes devices for small bones and joints, particularly focusing on trauma and arthroplasty.

Spine Next is a biotech company that manufactures and markets orthopedic spinal implant devices for spinal fusion surgeries. Spine Next is a France-based company that was founded in 1999 and the company was acquired by Abbott on October 25, 2004.

Raymedica, Inc. is an emerging medical device manufacturer with headquarters in Minneapolis, Minnesota. Raymedica’s goal is to develop innovative solutions for the surgical treatment of patients with low back pain who have not responded to conservative care, thus improving the quality of life for these patients worldwide. This mission is accomplished by expanding and improving the technology invented by Raymedica’s founder, Charles D. Ray, M.D. Currently, the company’s efforts are devoted to the development of the PDN® prosthetic disc nucleus for the treatment of low back pain associated with degenerative disc disease. The PDN device is surgically implanted into the evacuated nucleus disc space of the lumbar spine. Once implanted, the device is intended to increase or maintain disc height thereby restoring normal biomechanics, thus relieving pain.