ZeroTo510

Bairitone Health, founded in 2022 and headquartered in Houston, Texas, develops innovative solutions for individuals with untreated obstructive sleep apnea. The company specializes in remote passive sensing technology that employs vibration sensors placed on the face during sleep to gather acoustic data from the upper airway. This data is then analyzed using sonar beam-forming algorithms and artificial intelligence, allowing for precise identification of sound locations associated with structural collapses in the upper airway during apnea episodes. By providing detailed insights, Bairitone Health enables healthcare professionals to formulate informed treatment plans for sleep apnea, addressing a critical health issue for many individuals.

EndoShunt Medical, founded in 2022 and based in Nashville, Tennessee, specializes in developing a medical device aimed at targeted hemorrhage control in emergency situations. The company's innovative device facilitates endovascular shunting of blood past hemorrhaging vessels, allowing surgeons to perform definitive repairs while maintaining blood flow. This technology is designed to enhance outcomes in critical care scenarios, addressing the urgent need for effective solutions in managing severe bleeding.

MIIST Therapeutics focuses on advancing pulmonary drug delivery systems and digital platforms to improve inhaled drug therapies. The company is developing innovative technology aimed at facilitating smoking cessation and addressing the health risks associated with tobacco use. By creating inhaler technology that targets the deepest areas of the lungs, MIIST enables rapid absorption of medications. This approach aims to enhance the effectiveness of inhaled treatments for various health conditions, starting with smoking addiction, and ultimately seeks to reduce the significant health burdens related to tobacco consumption.

Madernity offers AI-guided pelvic health programs at no cost. Its platform helps moms take charge of preparing for birth and recovering at home.

NeuroDyne specializes in developing medical technology aimed at diagnosing and treating neurological diseases. The company focuses on creating devices that alleviate seizure activity in children with congenital brain disorders, adults experiencing seizures, and veterans affected by brain damage. By providing innovative solutions, NeuroDyne enables medical professionals to offer effective relief to individuals suffering from the debilitating effects of seizures.

Novobeing is an immersive patient experience platform that leverages advanced virtual and mixed reality technologies to enhance hospital care. Its primary focus is to accelerate patient recovery and improve well-being through a library of evidence-based programs designed to reduce anxiety, stress, and pain. The platform is user-friendly and integrates smoothly into existing healthcare workflows, requiring minimal staff training. With over 50 therapeutic programs, Novobeing supports in-patient care during hospitalization, cancer treatments, and diagnostic procedures. Its clinically validated solutions are built for scalability, enabling healthcare providers to deliver engaging care while improving patient satisfaction and clinical outcomes. By combining immersive technology with a patient-centered approach, Novobeing aims to redefine the patient experience and deliver measurable cost savings in critical healthcare settings.

Augment Health focuses on enhancing the management of bladder dysfunction, particularly for the 7 million patients affected by neurological diseases or injuries. The company is developing a noninvasive bladder monitor along with an AI algorithm that allows for home diagnostics, addressing the high rate of inconclusive results seen in clinical settings. By shifting bladder health monitoring out of the clinic, Augment Health's technology aims to prevent complications such as bladder muscle atrophy by notifying patients or caregivers when the catheter is full, thus promoting better bladder health management. This innovation targets a significant market valued at $12.3 billion, providing a practical solution to improve the quality of life for individuals facing bladder dysfunction.

Winter Innovations is a medical device company based in Knoxville, TN, focused on enhancing patient outcomes following orthopedic injuries. Founded in 2018, the company is currently developing EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgeries. This innovative device aims to simplify and standardize the whip stitching process, providing surgeons with improved ease of use, speed, stability, and versatility. By streamlining these procedures, Winter Innovations seeks to enhance the efficiency and consistency of orthopedic reconstruction, ultimately benefiting both surgeons and patients.

Future Cardia is a healthcare company focused on developing an innovative insertable cardiac device aimed at monitoring heart failure and atrial fibrillation (AFIB). The device operates as a compact monitoring tool that is placed under the skin and covered with a special bandage, enabling the transmission of encrypted cardiac data to a smartphone. By analyzing changes in heart sounds and rhythms through cloud-based pattern recognition, Future Cardia's technology helps track the progression of heart failure and can significantly reduce unnecessary hospitalizations. This approach addresses critical needs in cardiac care, offering patients and healthcare providers valuable insights into heart health.

Azimuth Sleep Solutions is a medical device manufacturer focused on providing innovative solutions for obstructive sleep apnea. The company specializes in creating custom, strapless continuous positive airway pressure (CPAP) devices that are 3D printed and tailored to fit the unique dental and facial profiles of each customer. These precision-fit masks deliver air comfortably and effectively into the upper airway during sleep, significantly improving the user's sleep quality. Azimuth collaborates with medical artists, engineers, and key opinion leaders in sleep medicine and dental science to ensure that its products meet the highest standards of quality and efficacy.

Diatech Diabetes is a MedTech startup focused on improving the lives of diabetes patients through innovative monitoring solutions. The company has developed SmartFusion, a system designed for insulin pumps that enhances the accuracy of insulin delivery while detecting potential infusion set failures. By integrating its software with insulin pumps, SmartFusion utilizes an algorithm that processes data from the pump, continuous glucose monitors, and individual patient infusion habits. This personalized approach enables patients to effectively monitor their insulin dosages, reducing complications and tailoring treatment to their specific needs.

Fairway Biomed, Inc. is a St. Louis-based company that manufactures medical devices specifically designed for surgical oncology. Founded in 2018, the company has developed LIVO, a medical device that effectively controls bleeding during resection surgeries aimed at removing tumors from vital organs such as the liver, kidney, and lung. By addressing bleeding control challenges in solid organs, Fairway Biomed's innovations enhance surgical outcomes and increase the eligibility of patients for liver resections. The company's mission focuses on improving patient outcomes in surgeries intended to treat life-threatening conditions, particularly cancer.

Spiritum Solutions is striving to create a worry-free medical setting by virtually eliminating human error during patient recovery.

EMBrace Design is focused on improving the quality of life for over 5 million individuals suffering from back pain through innovative support technology. The company's flagship product, the patented "START" brace, offers controllable spinal traction while allowing users to maintain mobility and engage in daily activities without discomfort. This device aims to revolutionize the standard of care for low back pain patients, providing an alternative treatment option for conditions such as spinal stenosis and disc degeneration. Backed by extensive laboratory testing and positive preliminary clinical feedback, the START brace holds the potential to enhance therapy outcomes significantly, potentially reducing the need for costly spinal surgery.

Path Ex, Inc. is a Nashville-based company established in 2017 that specializes in the development of extracorporeal blood-cleansing equipment aimed at treating sepsis, a severe and often fatal condition linked to blood-borne infections. The company has created a proprietary technology that selectively separates and captures bacteria and toxins from human blood, offering a novel approach to treatment. Unlike traditional methods that rely on broad-spectrum antibiotics to kill infections, Path Ex's device effectively removes intact bacteria from the bloodstream, regardless of the bacteria type or antibiotic resistance. This innovative technology has the potential to improve patient outcomes by reducing diagnostic times, treatment costs, readmission rates, and fatalities associated with sepsis.

SOMAVAC Medical Solutions, Inc. is a medical technology company based in Memphis, Tennessee, that specializes in enhancing post-operative care. Founded in 2016, the company develops innovative solutions to address complications arising from surgeries, particularly those related to breast cancer, such as mastectomies and abdominoplasties. Its flagship product, the SOMAVAC 100, is a sustained vacuum system designed to improve the recovery experience by effectively removing excess fluids and mitigating the risk of seroma formation. By employing negative pressure therapy, SOMAVAC aims to hold tissue layers together during the healing process, thereby facilitating better outcomes for patients following various surgical procedures.

Cast21 is a medical product developer based in Memphis, Tennessee, focused on creating innovative orthopedic solutions for fracture and joint care. Established in 2015, the company has developed a waterproof and breathable cast designed to enhance patient comfort and facilitate recovery. Its unique design not only allows for skin hygiene—enabling patients to wash and scratch beneath the cast—but also supports the integration of electronic therapies aimed at reducing healing time. By prioritizing user experience and effective treatment, Cast21 seeks to improve the overall recovery process for individuals with orthopedic injuries.

FlexSpark develops a wearable electrical muscle stimulation device aimed at enhancing patient care in the context of deep vein thrombosis (DVT) prevention. The device functions by stimulating muscle contractions, which reduces muscle atrophy often seen in patients with limited mobility due to injuries or surgeries. In addition to supplementing anticoagulant treatments, the device improves blood circulation and muscle flexibility, thereby alleviating fatigue and facilitating quicker recovery. This innovation allows patients to potentially bypass lengthy rehabilitation processes by preventing blood clots associated with immobility.

RistCall is a developer of wearable technology aimed at enhancing patient safety and satisfaction in hospitals and senior care communities. By updating traditional call bell systems, RistCall's smartwatch devices facilitate improved communication between patients and nursing staff. This innovation not only helps to reduce the incidence of patient falls but also aims to enhance patient satisfaction scores, such as HCAHPS. Through its focus on wearable technology, RistCall addresses critical needs in healthcare settings, ultimately striving to create a safer and more responsive environment for patients.

Lineus Medical specializes in medical devices aimed at enhancing vascular access and preventing complications associated with intravenous (IV) therapy. The company's flagship product, the SafeBreak Vascular device, employs patented break-away technology that allows for a controlled separation in the IV tubing when excessive tension is applied. This innovation helps prevent dislodgement of access lines, reducing the risks of blood loss and infection, and ultimately improving the overall quality of care for patients undergoing IV treatment. By focusing on the safety and effectiveness of IV therapy, Lineus Medical addresses a critical aspect of patient care in healthcare settings.

SweetBio, Inc. is a medical device company based in Memphis, Tennessee, specializing in the research, development, and manufacturing of innovative wound care solutions. Founded in 2015, the company focuses on bioengineering membranes that utilize medical-grade Manuka honey to enhance healing and combat infections associated with wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. SweetBio's unique honey-incorporated absorbable membranes are designed to improve the efficacy of wound care treatments, offering healthcare professionals a new platform for addressing both chronic and acute wounds effectively.

GlucosAlarm is a company that focuses on improving diabetes management for patients by providing a more convenient and painless alternative to traditional blood glucose testing. The company has developed a patent-pending glucose sensor that measures sugar levels in urine, which is installed in a toilet and activated via a smartphone application. This innovative approach allows diabetic patients to monitor their glucose levels effortlessly, fitting seamlessly into their daily routines. By offering a user-friendly and cost-effective solution, GlucosAlarm aims to help individuals manage their condition more effectively and reduce the risk of complications associated with diabetes.

Inspire Living, Inc. is a healthcare technology company based in Fairfax, Virginia, founded in 2011. The company specializes in developing portable pediatric respiratory monitoring devices, notably its flagship product, INSPIRE. This automated electronic device employs patented algorithms to accurately measure breath rate, heart rate, anxiety levels, and body position, allowing caregivers to assess respiratory illnesses effectively. INSPIRE serves as a diagnostic aid that can be used in various settings, including clinics, homes, and remote areas, facilitating quick and efficient medical evaluations in just one minute. Its innovative design incorporates pediatric respiratory rate sensors and a banding system that collects bio-electrical signals, enabling healthcare providers to detect early signs of conditions such as childhood pneumonia. Additionally, Inspire Living's secure platform ensures safe transmission of patient data, enhancing the capabilities of remote diagnostics.

EndoInSight specializes in developing a disposable insufflation system aimed at alleviating the pain and discomfort associated with colonoscopy procedures used for colorectal cancer screening. The company utilizes carbon dioxide for colon inflation, a method that significantly reduces post-procedural discomfort compared to traditional air insufflation. Despite the known advantages of using CO2, its adoption in clinical settings has been limited due to low awareness and the high costs of existing insufflation systems. By offering a cost-effective solution, EndoInSight seeks to enhance patient comfort and improve overall outcomes in colorectal cancer treatment.

Innometrix, Inc. is a Memphis-based company focused on developing advanced technology to enhance the diagnosis and treatment of female pelvic floor disorders. These conditions are prevalent, affecting approximately 50% of women who have given birth, and they contribute to significant healthcare costs. Innometrix aims to translate biomechanics into clinical solutions by producing a biomechanical snapshot of the female pelvic floor, providing physicians with vital data prior to surgical procedures. The company addresses the limitations of current treatment methods, which often rely on subjective judgment and have high complication rates. By creating innovative device solutions, Innometrix seeks to improve treatment outcomes and increase patient satisfaction in a field that requires significant advancements.

Blood Monitoring Solutions, Inc. is dedicated to developing innovative blood monitoring systems aimed at reducing blood wastage. Based in Memphis, Tennessee, the company has created a smart blood transport system that enables blood banks to continuously monitor the temperature and integrity of each blood unit. This proactive, data-driven approach not only enhances patient safety but also helps hospitals minimize costs associated with blood spoilage. By ensuring that blood is stored within the appropriate temperature range, the company's solutions allow for longer preservation of blood supplies, ultimately supporting more effective transfusion practices in healthcare settings.

Compression Kinetics, Inc. is a Memphis-based company specializing in the design and development of innovative medical devices, particularly dynamic compression sleeves. These sleeves utilize shape memory alloy technology to generate pressure waves that enhance circulation, reduce peripheral edema, and help prevent blood clots. By translating clinically proven compression therapy into a sleek and mobile format, Compression Kinetics is positioned to make a significant impact in the $11 billion athletic compression apparel market. The company's products aim to improve recovery times and athletic performance for users, making advanced compression therapy accessible to both amateur and professional athletes.

Better Walk Inc. is an innovative company that specializes in the design and development of crutches. Established in 2013 and headquartered in Atlanta, Georgia, the company aims to improve traditional crutch technology by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. Better Walk's commitment to innovation is a fundamental aspect of its culture, which was further strengthened during its participation in the Zero To 510 accelerator in Memphis, where it secured early venture funding. In late 2014, the company shifted its focus to finalizing the Better Walk crutch, positioning itself for production and an anticipated product launch in early 2015.

Mobilizer Inc. is a company that specializes in the development of innovative six-wheeled holsters designed for medical equipment, aimed at enhancing the efficiency of patient ambulation in healthcare settings. Modeled after a wheeled walker, these holsters feature shelves and attachments that facilitate the transportation of equipment necessary for the mobility of critical care patients. By improving the process of medical ambulation, Mobilizer aims to enhance patient well-being while streamlining operations within hospitals. The company is a graduate of the ZeroTo510 medical device startup accelerator, further validating its commitment to advancing healthcare solutions.

Cuff-Mate skin barriers offer healthcare professionals a cost-effective way to protect their patients, themselves and equipment when taking vital signs.

Although it is still relatively new, AIS, having a relationship with other biology-inspired computing models, and computational biology.

Health & Bliss Inc. is a medical device company based in Memphis, Tennessee, specializing in the design, patenting, and sale of medical products and diagnostic tests. The company has developed Strep Test Anywhere, an innovative point-of-care device that enables testing for multiple infections, including strep throat, influenza A/B, chlamydia, gonorrhea, hepatitis B/C, and several other illnesses. By providing a means to obtain accurate test results without the need for a doctor visit, Health & Bliss aims to address significant barriers to effective healthcare, specifically time and cost. Their technology is designed to improve patient access to diagnostic services while benefiting healthcare providers and payers alike.

Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.

Nanophthalmics is a developer of innovative surgical devices and techniques aimed at enhancing treatment outcomes for ophthalmic and microsurgical diseases. The company has created a patent-pending platform technology for microfabricated instruments that engage tissue in novel ways. Their flagship product is a disposable corneal micro-punch, which is designed to improve healing in cases of abrasions, recurrent erosions, and other corneal diseases by altering tissue attachments at the cellular level. By focusing on advanced surgical devices and methods, Nanophthalmics seeks to transform the landscape of ophthalmic treatment and offer better solutions for healthcare providers.

Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on creating innovative solutions for stress urinary incontinence in women. Founded in 2012, the company developed its technology through a collaborative effort by biomedical engineering students at Johns Hopkins University, guided by expert physicians from the institution's renowned urological center. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and convenient treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which is supported by local venture capital firms, further enhancing its development and outreach efforts.

EcoSurg is a developer of environmentally-friendly surgical supplies aimed at minimizing the carbon footprint in surgical settings. The company’s primary product, the EcoSurg line of patient positioners, consists of disposable foam shapes designed for use in over 20 million surgical procedures annually in the United States. These positioners help ensure patient safety, comfort, and proper access to surgical sites. Traditional disposable positioners are made from petroleum-based materials, which pose environmental hazards and lead to increased disposal costs. EcoSurg's innovative approach seeks to address these concerns by providing sustainable alternatives that reduce environmental impact while maintaining the necessary functionality for surgical procedures.

BioNanovations is a medical technology company focused on the rapid diagnosis of bacterial infections, particularly Staphylococcus infections. Currently, diagnosing these infections takes 3 to 5 days, which can be critical due to the aggressive nature of certain strains that may lead to severe health consequences, including limb amputation or death within 48 hours. To address these challenges, BioNanovations is developing a handheld diagnostic platform that significantly reduces the testing time to under 30 minutes. This integrated real-time diagnostic solution enables healthcare professionals to quickly analyze blood, sputum, urine, and cerebrospinal fluid, facilitating immediate access to vital diagnostic information. By providing real-time data on bacterial infections, the platform not only improves patient outcomes by reducing morbidity and mortality rates but also supports healthcare professionals and agencies in tracking epidemiological trends effectively.

HandMinder is a developer of a portable hand rehabilitation device designed to aid stroke survivors in regaining hand function. With approximately 7 million stroke survivors in the United States and 795,000 new or recurrent cases each year, many face significant hand dysfunction, which affects their quality of life. Current rehabilitation methods primarily focus on muscle rehabilitation, often leaving patients in a passive role, and can be both expensive and inconvenient. Recognizing the need for more effective solutions, HandMinder utilizes patent-pending vibration-guided brain engagement technology that enhances neural connections between the hand and brain. Research indicates that this active engagement can double the amount of hand movement and improve its quality by 2.5 times compared to traditional treatments. The HandMinder device is designed to be affordable and convenient, making it suitable for use in both clinical settings and at home, ultimately aiming to improve rehabilitation outcomes for stroke victims.