ZeroTo510

Bairitone Health is a Houston-based company founded in 2022 that focuses on creating innovative solutions for individuals suffering from untreated obstructive sleep apnea. The company has developed remote passive sensing technology that employs vibration sensors placed on the face during sleep to gather acoustic data from the upper airway. This data is then analyzed using advanced sonar beam-forming algorithms and artificial intelligence to accurately identify the location of structural collapses in the upper airway that contribute to apnea episodes. By providing detailed insights into the nature of a patient's condition, Bairitone Health enables healthcare professionals to devise more informed and effective treatment plans for sleep apnea.

EndoShunt Medical is a Nashville, Tennessee-based company founded in 2022 that specializes in developing medical devices for targeted hemorrhage control in emergency situations. The company has created a device designed to shunt blood past hemorrhaging vessels endovascularly, allowing surgeons to perform definitive repairs while maintaining blood flow. This innovative approach aims to enhance patient outcomes during critical medical emergencies by providing effective hemorrhage management.

MIIST Therapeutics focuses on advancing pulmonary drug delivery systems and digital platforms to improve inhaled drug therapies. The company is developing innovative technology aimed at facilitating smoking cessation and addressing the health risks associated with tobacco use. By creating inhaler technology that targets the deepest areas of the lungs, MIIST enables rapid absorption of medications. This approach aims to enhance the effectiveness of inhaled treatments for various health conditions, starting with smoking addiction, and ultimately seeks to reduce the significant health burdens related to tobacco consumption.

Madernity is a health technology company that provides AI-driven pelvic health programs for mothers, free of charge. Its platform empowers women to manage their birth preparation and post-natal recovery at home, using real-time feedback and posture correction through computer vision and pose estimation technology, mimicking the effectiveness of in-person physical therapy.

NeuroDyne specializes in developing medical technology aimed at diagnosing and treating neurological diseases. The company focuses on creating devices that alleviate seizure activity in children with congenital brain disorders, adults experiencing seizures, and veterans affected by brain damage. By providing innovative solutions, NeuroDyne enables medical professionals to offer effective relief to individuals suffering from the debilitating effects of seizures.

Augment Health is a company focused on developing noninvasive medical devices and artificial intelligence algorithms to enhance the management of bladder dysfunction, particularly for the 7 million patients affected by neurologic disease or injury. The company's innovative technology allows for monitoring urine levels through a device that can be attached to catheters, providing timely notifications to users or care providers when the catheter reaches capacity. This approach aims to shift bladder diagnostics from clinical settings to patients' homes, addressing the high rate of inconclusive test results associated with traditional in-clinic diagnostics. By enabling better bladder health management, Augment Health seeks to prevent complications such as bladder muscle atrophy, ultimately improving the quality of life for patients.

Novobeing is a pioneer in the field of patient care, offering an immersive platform that integrates virtual and mixed reality technologies aimed at enhancing the healthcare experience. The platform features over 50 evidence-based therapeutic programs designed to alleviate anxiety, stress, and pain across various medical settings, including hospitalizations, cancer treatments, and diagnostic procedures. Novobeing's self-administered solution seamlessly fits into existing workflows, requiring minimal training for healthcare staff and facilitating efficient resource utilization. By combining gamified digital interventions with clinically validated therapies, Novobeing not only supports the healing process but also promotes patient satisfaction and accelerates recovery. The clinically validated platform empowers healthcare providers to deliver transformative care, optimize clinical outcomes, and reduce overall healthcare costs, establishing Novobeing as a key player in the evolution of patient-centered care.

Winter Innovations is a Knoxville, Tennessee-based startup founded in 2018 that focuses on developing medical devices aimed at enhancing patient outcomes in orthopedic care. The company is in the process of launching EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgery. This innovative device seeks to simplify and standardize the whip stitching technique, offering advantages such as ease of use, speed, stability, and versatility. Through these improvements, Winter Innovations aims to help surgeons perform orthopedic reconstruction procedures more efficiently and consistently.

Future Cardia is a healthcare company focused on developing a compact cardiac device aimed at monitoring heart failure and cardiac arrhythmias. The system utilizes a digital health insertable device that is placed under the skin and covered with a specialized bandage. This device continuously analyzes heart sounds and rhythms, employing cloud-based pattern recognition to track the progression of heart failure. By doing so, it helps reduce unnecessary hospitalizations by transmitting encrypted cardiac data directly to a smartphone, allowing for timely monitoring and intervention. Future Cardia's innovative approach addresses critical needs in cardiac care, enhancing patient outcomes through advanced technology.

Azimuth Sleep Solutions is a medical device manufacturer focused on providing innovative solutions for obstructive sleep apnea. The company specializes in a custom-fit, strapless CPAP device that is 3D printed and shipped directly to customers. Designed by a team of medical artists and engineers, the product aims to deliver air precisely and comfortably into the upper airway during sleep, enhancing the user's overall sleep quality. Azimuth collaborates closely with key opinion leaders in sleep medicine and dental science to ensure that its products meet high standards of quality and efficacy, ultimately addressing the specific needs of patients with sleep apnea.

Diatech Diabetes is a MedTech startup focused on improving the lives of individuals with diabetes through innovative monitoring solutions. The company has developed SmartFusion, a sophisticated system designed for insulin pumps that enhances the accuracy of insulin delivery and detects infusion set failures. By integrating its software with existing insulin pumps, SmartFusion utilizes data from the pump, continuous glucose monitors, and the patient's infusion habits. This approach allows for personalized insulin management, enabling patients to better monitor their daily dosages and reduce the risk of complications. Diatech Diabetes aims to provide tailored solutions that address the unique needs of diabetes patients, ultimately promoting better health outcomes.

Hera Health Solutions, Inc. is a biotechnology company focused on the development and commercialization of innovative drug delivery systems, particularly long-acting therapeutics. Founded in 2017 and headquartered in Frisco, Texas, the company specializes in biodegradable implants that release contraceptive hormones over time. Its flagship product, Eucontra, is designed to resorb into the body after delivering the medication, thereby simplifying the administration of contraceptives and improving patient adherence. By leveraging advanced materials and manufacturing techniques, Hera Health Solutions aims to transform the landscape of long-acting drug delivery and address healthcare accessibility issues.

Fairway Biomed, Inc. is a medical device manufacturer based in St. Louis, Missouri, established in 2018. The company specializes in developing surgical tools aimed at enhancing outcomes in surgical oncology, particularly in the treatment of life-threatening diseases like cancer. Its flagship product, LIVO, is designed to control bleeding during resection surgeries for tumors located in solid organs such as the liver, kidney, and lung. By addressing bleeding control challenges, Fairway Biomed's devices enable surgeons to manage intraoperative bleeding risks more effectively, thereby increasing the eligibility of patients for liver resection procedures.

Spiritum Solutions is striving to create a worry-free medical setting by virtually eliminating human error during patient recovery.

EMBrace Design focuses on improving the quality of life for individuals suffering from back pain through innovative technology. The company's flagship product, the patented "START" brace, offers a unique approach by providing controllable spinal traction while allowing users to engage in daily activities without pain. This device is specifically designed to change the standard of care for low back pain patients, addressing conditions such as spinal stenosis and disc degeneration. Backed by extensive laboratory testing and encouraging preliminary clinical feedback, EMBrace Design aims to enhance therapeutic outcomes, potentially reducing the need for costly spinal surgeries, which can average $100,000 per patient.

Path Ex, Inc. is a Nashville, Tennessee-based company founded in 2017 that specializes in the manufacture of extracorporeal blood cleansing equipment. The company has developed a proprietary technology aimed at selectively separating and capturing bacteria and toxins from human blood, specifically for the treatment of sepsis, a critical condition often linked to blood-borne infections. Unlike conventional methods that rely on antibiotics to combat infections, Path Ex's innovative approach focuses on removing intact bacteria from the bloodstream, making it effective against various bacteria types and drug-resistant strains. This technology has the potential to significantly improve patient outcomes by reducing diagnostic times, lowering treatment costs, decreasing readmission rates, and ultimately decreasing sepsis-related mortality.

FlexSpark is a developer of a wearable electrical muscle stimulation device focused on enhancing patient care during periods of limited mobility. This innovative device is designed to supplement anticoagulant therapies and prevent deep vein thrombosis (DVT) by stimulating muscle contractions. In doing so, it helps reduce muscle atrophy and increases blood circulation, thereby improving muscle flexibility. The technology enables patients recovering from injuries or surgeries to potentially bypass lengthy rehabilitation processes and enhances overall mobility. By addressing the challenges associated with immobility, FlexSpark aims to improve patient outcomes and support recovery in individuals with restricted movement.

Cast21 is a developer of orthopedic medical products based in Memphis, Tennessee, that specializes in creating waterproof and breathable casts for fracture and joint care. Founded in 2015, the company focuses on innovative designs that enhance patient comfort and promote healing. Its products utilize lightweight materials that allow for skin care and hygiene while wearing the cast. Additionally, Cast21's designs facilitate the integration of electronic therapies to potentially reduce healing time, offering a modern solution for patients recovering from injuries.

SOMAVAC Medical Solutions, Inc. is a medical technology company based in Memphis, Tennessee, that specializes in enhancing post-operative care. Founded in 2016, the company develops innovative solutions aimed at improving recovery outcomes for patients undergoing various surgical procedures, particularly those at risk of seroma complications, such as breast surgeries and abdominoplasty. SOMAVAC Medical's flagship product, the SOMAVAC 100, is a sustained vacuum system designed to facilitate the removal of fluids and maintain tissue adhesion during recovery. By focusing on the challenges associated with surgical drains and fluid accumulation, SOMAVAC Medical Solutions aims to optimize the healing process and improve the overall patient experience following surgery.

RistCall is a company that develops smartwatch devices aimed at enhancing patient safety and satisfaction in healthcare settings, particularly hospitals and senior care communities. By replacing traditional call bell systems with their innovative wearable technology, RistCall facilitates improved communication between patients and nursing staff. This approach not only helps to reduce the incidence of falls but also enhances overall patient satisfaction, as measured by HCAHPS scores. Through its focus on wearable technology, RistCall addresses critical needs in patient care, ensuring a safer and more responsive healthcare environment.

Lineus Medical is a company that specializes in medical devices aimed at reducing complications associated with intravenous (IV) therapy and enhancing vascular access outcomes. Its flagship product, the SafeBreak Vascular device, employs patented break-away technology designed to create a safe separation in IV tubing under excessive tension. This innovative mechanism helps prevent dislodgement of access lines, a common issue that can lead to blood loss and infection, thus improving the overall quality of care for patients undergoing IV therapy.

SweetBio, Inc. is a medical device company focused on the research, development, and manufacturing of innovative wound care solutions. Established in 2015 and headquartered in Memphis, Tennessee, SweetBio specializes in bioengineering membranes that incorporate medical-grade Manuka honey, which aids in healing and combating bacterial infections associated with various types of wounds, including surgical wounds, pressure ulcers, and diabetic ulcers. The company aims to revolutionize wound care by offering absorbable membranes that enhance the efficacy of treatments for both chronic and acute wounds, thereby improving patient outcomes for medical practitioners.

GlucosAlarm is a company focused on improving diabetes management for patients worldwide, addressing a significant global health issue affecting nearly 400 million individuals. The company has developed a patent-pending glucose sensor that offers a more convenient and less painful alternative to traditional blood testing methods. This innovative sensor is designed to be installed in a toilet, where it measures glucose levels in urine and operates via a smartphone application. GlucosAlarm's solution is user-friendly and affordable, seamlessly integrating into the daily routines of diabetic patients. By facilitating easier monitoring of glucose levels, the company aims to help users manage their condition effectively and avoid potentially serious complications associated with diabetes.

Inspire Living, Inc. is a healthcare technology company based in Fairfax, Virginia, established in 2011. The company specializes in developing mobile pediatric respiratory monitoring devices, particularly its flagship product, INSPIRE. This automated electronic device employs patented algorithms to accurately assess vital signs, including breath rate, heart rate, anxiety levels, and body position. INSPIRE is designed to facilitate advanced diagnostic examinations by caregivers, ranging from individual users to healthcare professionals, in various settings such as clinics, homes, and remote locations. The device's capabilities allow for rapid and effective monitoring of respiratory illness, enabling timely intervention. Additionally, INSPIRE features a proprietary platform for secure transmission of patient data, enhancing remote diagnostics and improving overall patient care.

EndoInSight is a company focused on addressing the significant impact of colorectal cancer by offering a disposable insufflation system that enhances the comfort of patients undergoing colonoscopy-based screenings. The system utilizes carbon dioxide to inflate the colon, a method known to alleviate post-procedural pain and discomfort that often follows traditional air insufflation. Despite the recognized benefits of using carbon dioxide, its adoption in clinical settings has been limited due to a lack of awareness and the costs associated with existing CO2 insufflation systems. By providing a cost-effective solution, EndoInSight aims to improve patient outcomes and increase the acceptance of this more comfortable approach to colorectal cancer screening among healthcare professionals.

Innometrix, Inc. is a Memphis, Tennessee-based company focused on developing innovative technologies to address female pelvic floor disorders. By translating the science of biomechanics into clinical applications, Innometrix aims to provide physicians with enhanced diagnostic tools that create a biomechanical snapshot of the pelvic floor. This technology is designed to improve pre-surgical data, ultimately leading to better treatment outcomes and increased patient satisfaction. Female pelvic floor disorders are prevalent, affecting approximately 50% of women who have given birth, and current treatment methods often involve surgical procedures with high complication and revision rates. Innometrix seeks to revolutionize the diagnosis and treatment of these conditions by offering device solutions that alleviate challenges faced by clinicians, thereby contributing to a critical area in women's health that requires significant innovation.

Blood Monitoring Solutions, Inc. is a Memphis, Tennessee-based company that specializes in developing innovative blood monitoring systems aimed at reducing blood wastage. The company has created a smart blood transport system that enables blood banks to proactively monitor the temperature and presence of each blood unit. This data-driven technology ensures that blood is maintained within the correct temperature range, thereby preventing spoilage and enhancing patient safety. By improving the management of blood supplies, Blood Monitoring Solutions not only helps hospitals preserve blood for longer periods but also contributes to cost reductions in healthcare settings.

Compression Kinetics, Inc., based in Memphis, Tennessee, specializes in the design and development of innovative medical devices, particularly advanced compression sleeves. These devices utilize shape memory alloy to generate a pressure wave that enhances circulation, reduces peripheral edema, and helps prevent blood clots. The company is at the forefront of wearable technology, transforming clinically proven compression therapy into sleek and affordable solutions. By improving recovery times and athletic performance, Compression Kinetics aims to provide athletes with the tools to enhance their performance, making high-quality compression therapy accessible to a broader audience within the growing athletic compression apparel market.

Better Walk Inc. is an innovative company based in Atlanta, Georgia, specializing in the design and development of crutches. Founded in 2013, the company aims to enhance the traditional crutch design by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. The organization emphasizes continuous innovation, recognizing the need for advancements in even the most established technologies. Better Walk gained early support through the Zero To 510 accelerator program in Memphis, Tennessee, which facilitated its initial funding. Since relocating to Atlanta in late 2014, the company has focused on refining its flagship product, the Better Walk crutch, and is preparing for its production and launch.

Mobilizer Inc. is a company focused on enhancing medical ambulation through its innovative design of a six-wheeled holster for medical equipment. Modeled after a wheeled walker, this holster features shelves and attachments that facilitate the safe and efficient transport of equipment for critical care patients. By streamlining the ambulation process, Mobilizer aims to improve patient well-being and increase operational efficiency within healthcare settings. The company emerged from the ZeroTo510 medical device startup accelerator, reflecting its commitment to advancing medical technology solutions.

Cuff-Mate skin barriers offer healthcare professionals a cost-effective way to protect their patients, themselves and equipment when taking vital signs.

Health & Bliss Inc. is a medical device company based in Memphis, Tennessee, specializing in the design, patenting, and sale of innovative medical products and diagnostic tests. The company has developed Strep Test Anywhere, a point-of-care device that enables testing for multiple infections, including strep throat, influenza A/B, chlamydia, gonorrhea, and several others, directly at the patient's location. This technology aims to eliminate barriers to effective healthcare by providing rapid and affordable testing solutions, ensuring accurate results without the need for a doctor's visit. By addressing key concerns such as time and cost, Health & Bliss seeks to empower patients and healthcare providers alike.

Although it is still relatively new, AIS, having a relationship with other biology-inspired computing models, and computational biology.

Restore Medical Solutions, Inc., established in 2012 and based in Memphis, Tennessee, specializes in manufacturing modular sterilization tray systems for hospitals and surgery centers. Their products aim to reduce surgical site infections (SSIs), enhance safety, and improve productivity within the healthcare industry by minimizing the risk of contamination from medical instruments.

Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on developing innovative solutions to address stress urinary incontinence in women. Founded in 2012, the company emerged from a project by undergraduate biomedical engineers at Johns Hopkins University, where its technology was refined with guidance from leading physicians at one of the top urological centers in the United States. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and safe treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which supports health-focused startups in the region.

EcoSurg is a company focused on the development of environmentally-friendly surgical supplies aimed at minimizing the carbon footprint of surgical procedures. Their primary product line features disposable patient positioners, which are utilized in over 20 million surgeries annually in the United States. These foam positioners are designed to safely and comfortably support patients in various positions, providing essential access to surgical sites. However, traditional positioners are largely made from petroleum-based materials, which pose environmental risks and lead to increased handling and disposal costs. EcoSurg's commitment to sustainability seeks to address these issues by offering solutions that reduce the ecological impact of surgical practices while maintaining patient safety and comfort.

Nanophthalmics is a company focused on developing innovative surgical devices and techniques aimed at improving treatment outcomes for ophthalmic and other microsurgical diseases. They have created a patent-pending platform technology for microfabricated instruments that interact with tissue in novel ways. Their first commercial product is a disposable corneal micro-punch, which is 510(k) exempt and designed to promote healing for corneal abrasions, recurrent erosions, and various corneal diseases by modifying tissue attachments at the cellular level. Through their advancements, Nanophthalmics seeks to enhance the efficacy of surgical interventions in the eye care sector.

BioNanovations is a medical device company based in the United States, specializing in the development of a handheld diagnostic platform that utilizes bionanotechnology to identify bacterial infections, specifically Staphylococcus infections. The company aims to significantly reduce the diagnostic time from the current 3-5 days to under 30 minutes, addressing the urgent need for timely diagnosis due to the potential severity of aggressive strains that can lead to serious health complications. The platform is designed to monitor various biological samples, including blood, sputum, urine, and cerebrospinal fluid, providing healthcare professionals with immediate access to diagnostic information. This innovation not only enhances patient care by improving diagnostic efficiency but also facilitates the transmission of epidemiological data, enabling better tracking of infection trends. BioNanovations targets hospitals, healthcare providers, and government agencies, ultimately striving to improve patient outcomes by reducing morbidity and mortality associated with bacterial infections.

HandMinder is a company focused on enhancing rehabilitation for stroke survivors suffering from hand dysfunction, a condition affecting approximately 60% of the 7 million stroke survivors in the United States. The company has developed a portable hand rehabilitation device that utilizes patent-pending vibration-guided brain engagement technology. This innovative approach aims to strengthen the neural connections between the hand and brain, resulting in significant improvements in hand function. Unlike traditional rehabilitation methods, which often require a passive role from the patient and can be costly, HandMinder's device promotes active engagement, leading to twice the improvement in hand movement and 2.5 times better quality of movement. The device is designed to be affordable and convenient, making it suitable for use in both clinical and home settings, thereby addressing the growing need for effective rehabilitation solutions for stroke victims.