New Brunswick Innovation Foundation (NBIF), established in 2003, is a Canadian venture capital firm based in Fredericton. It invests in early-stage, growth-oriented companies and applied research projects, primarily in New Brunswick. Unlike traditional financial institutions, NBIF invests in companies' equity and provides funding to research projects with commercialization potential. The foundation's unique approach involves attaching certain rights to developed intellectual property to facilitate its commercialization. NBIF manages $40 million and has helped leverage over $160 million in additional capital for its portfolio companies and researchers. Its mission is to foster innovation and create commercial opportunities in New Brunswick's strategic industries.

East Valley Ventures is an angel investment group and community of entrepreneurs based in Saint John, New Brunswick, Canada, with a focus on early-stage technology startups across Atlantic Canada. Founded in 2011, it seeks opportunities in the information and communications technology sector and supports Atlantic Canadian founders in turning early ideas into meaningful, enduring technology companies through capital and guidance.

Established in 1973, Johnson & Johnson Innovation facilitates early-stage innovation through strategic partnerships. It connects potential collaborators with resources to advance transformative science and technology across pharmaceuticals, medical devices, and consumer healthcare sectors.

Build Ventures is a Halifax-based venture capital firm that backs early-stage technology companies across Atlantic Canada. Founded in 2013, it focuses on sectors such as information technology, clean technology, life sciences, and life sciences tools and services, investing after the seed round to help founders build scalable businesses in large markets. Typical investments range from CAD 1 million to CAD 5 million, with initial commitments of CAD 0.5 million to CAD 2 million. The firm brings operational and investment experience to assist founders in navigating growth, team development, and product-market fit within the Atlantic Canadian ecosystem.

Established in 2017, Drone Fund is a Tokyo-based venture capital firm focused on investing in drone and related technologies.

Cavallo Ventures is the corporate venture arm of Wilbur-Ellis Holdings, based in San Francisco. It invests its own capital in early-stage ventures across livestock feed, pet nutrition, aquafeed, and related ingredients and formulation, including cosmetics and nutrition products for humans and animals. The firm looks for innovative solutions in areas such as water management, irrigation, soil biology, and resource conservation, and supports startups advancing agricultural and ecological sustainability. By partnering with entrepreneurs, Cavallo Ventures aims to accelerate commercialization of scalable technologies that align with Wilbur-Ellis’ core feed, nutrition, and agrochemical interests.

Founded in 2014, Builders VC is a San Francisco-based venture capital firm focused on early-stage investments. It specializes in sectors where technology intersects with new business models to modernize industries such as healthcare, agriculture, industrials, and real estate.

Fonds de solidarité FTQ is a private equity and venture capital firm based in Montreal, Canada, with additional offices in Quebec. Established in 1983, the firm specializes in investing in small and medium-sized businesses across various sectors, including natural resources, aerospace, agri-food, life sciences, and culture. It primarily focuses on projects that require funding of $3 million or more and provides loans up to $2 million. The firm actively seeks investment opportunities in Quebec, particularly in regions such as Abitibi-Témiscamingue and Montérégie. Fonds de solidarité FTQ invests in a range of activities, including business succession, financial restructuring, and market development, while avoiding sectors like retail, real estate, and biotechnology. It typically engages in equity financing and unsecured debt with investment horizons ranging from five to ten years. The firm aims to support projects that positively impact the Quebec economy and often takes either minority or majority stakes in its portfolio companies.

Founded in 1953, BDC Capital is a Canadian investment firm specializing in growth and expansion financing. It focuses on information technology, technology, energy, cleantech, and healthcare sectors across Canada.

Established in Canada since 1992, GrowthWorks is an asset management firm specializing in early-stage investments across cleantech, healthcare, and technology sectors. The company manages regional venture capital funds nationwide, providing strategic investment structuring, risk diversification, and industry connections to foster growth-oriented companies.

Rho Capital Partners is a principal investment firm established in 1981 and headquartered in New York, with additional offices in Palo Alto and Montreal. It pursues direct investments and fund of funds strategies, targeting seed through growth stages across technology, media, communications, healthcare, life sciences, energy technology, and related fields, including software (notably SaaS), mobile, semiconductors, and IT. The firm pursues global opportunities, with activity in North America and Europe, and has historically invested in ventures across early to late stages, taking minority and majority positions. It operates four divisions—Rho Ventures, Rho Canada Ventures, Rho Fund Investors, and Rho Acceleration—through which it backs high-growth entrepreneurs and helps scale innovative companies. The firm also invests in venture capital funds and aims to support companies that redefine industries, emphasizing unconventional ideas and long-term impact.

Founded in 2011, Fortify Ventures is an early-stage venture capital firm based in New York. It invests in innovative founders disrupting technology sectors such as human health and the future of work.

Leaps by Bayer is the corporate venture capital arm of Bayer. Established in 2015 and headquartered in Leverkusen, Germany, it invests in life sciences, including healthcare, biotechnology, and agriculture. The firm seeks long-term, disruptive technologies and supports innovations with potential for significant societal impact.

Monsanto Growth Ventures (MGV) is the venture capital group at Monsanto Company, a leading provider of technology-based solutions and agricultural products that enhance farm productivity and food quality. MGV aims to support early-stage companies by providing capital and leveraging Monsanto's agricultural expertise and resources. By fostering an innovation supply chain that includes researchers, entrepreneurs, and other venture capitalists, MGV helps small independent teams rapidly prototype innovations to bring solutions to the agricultural market. With a global reach, MGV has invested in and partnered with small companies worldwide, assisting them in navigating the challenges of product development and market entry. Through patient investment and access to field testing and market intelligence, MGV works to position products for success in the agriculture industry.

Mavan Capital Partners is a venture capital investment firm established in 2017 and headquartered in Kelowna, Canada. The firm specializes in actively investing in technology companies both in Canada and internationally. Mavan Capital Partners focuses on fostering growth by connecting investors with innovative portfolio companies in the technology sector. Through its dedication to the technology arena, the firm aims to support the development of ideas and drive progress in the industry.

Established in 2001, Sustainable Development Technology Canada (SDTC) is a Canadian organization that funds and supports innovative cleantech projects. It focuses on moving groundbreaking technologies to market, creating jobs, driving economic growth, and promoting environmental benefits. SDTC operates independently but collaborates with various stakeholders from private industry, academia, and governments.

New York Ventures is a venture capital investment arm of Empire State Development that supports innovation and economic growth across New York State. It provides resources and investment opportunities through programs such as Governor's START‑UP NY, Innovation Hot Spots, Regional Economic Development Councils, Centers of Advanced Technology, Centers of Excellence, and the SUNY 2020 Initiative.

iGan Partners is a Canadian private equity and venture capital firm that targets early-stage investments in healthcare and technology. The firm focuses on AI-enabled MedTech, digital health, and B2B software, backing dynamic management teams with smart capital and an active management approach. iGan Partners emphasizes strategic value creation through access to a broad network of industry partners and sector-specific co-investors, helping portfolio companies navigate growth challenges and accelerate commercial success. Alongside its sister fund Rowanwood Ventures, it supports emerging technology companies and draws on experience building successful businesses to assist growing companies. The firm positions itself as a partner for early-stage companies seeking to scale in healthcare and technology domains.

Virginia Venture Partners is a corporate venture capital firm based in Richmond, Virginia, established in 2005 as a part of the Virginia Innovation Partnership. The firm focuses on seed-stage investments in technology, life sciences, cleantech, and energy startups located in Virginia. By providing near-equity and equity investments, Virginia Venture Partners aims to foster rapid growth in its portfolio companies while generating significant economic returns for entrepreneurs and co-investors. The firm's investment strategy includes dedicated funds such as the GAP BioLife Fund, which targets life science companies, and the GAP Tech Fund, focusing on IT and technology firms. Through these investments, Virginia Venture Partners seeks to contribute to the economic development of the Commonwealth of Virginia.

Lake Bridge Capital is an investment firm established in 2016 that operates as a private investment fund, applying capital and driving operational focus to support portfolio companies' strategic growth.

Founded in 2009, Espresso Capital provides flexible, founder-friendly venture debt solutions to over 330 early and growth-stage technology companies across the U.S., Canada, and the UK. Its mission is to empower entrepreneurs by offering lines of credit and term loans that enable business growth without dilution or personal guarantees.

The Mahindra Group is an Indian multinational conglomerate with a diversified portfolio spanning automotive vehicles, farm equipment, financial services, real estate, and technology. It operates globally, generating significant revenue from its automotive segment, which includes the manufacture and sale of automobiles, spares, mobility solutions, construction equipment, and related services.

L-SPARK Corporation is an accelerator and incubator based in Ontario, Canada, focused on investing in B2B startups, particularly in the cloud computing software and SaaS sectors. Established in 2014, L-SPARK selects up to eight startups every six months for its incubator program, providing funding, mentoring, and various support services valued at approximately $40,000 at no cost. Startups can receive initial investments and additional funding upon graduation, with a focus on helping them secure further investments. The firm also operates an accelerator program for post-incubator companies, where selected startups receive equity funding and further financial support based on performance. L-SPARK aims to foster significant revenue growth and facilitate access to venture capital and investment opportunities. Additionally, it collaborates with corporate partners to drive innovation in areas such as autonomous vehicles and secure IoT solutions. With a successful track record, over 50% of the companies accelerated by L-SPARK have raised follow-on funding, totaling more than $45 million.

43North is a startup competition and accelerator program established in 2014 in Buffalo, New York, dedicated to attracting and retaining high-growth companies. Each year, it invests $5 million, primarily in pre-seed or seed stage companies that have a deployable product, customer traction, and revenue. In exchange for 5% equity, 43North offers investments of either $500,000 or $1 million, along with mentorship and access to a broad network of investors, customers, vendors, and alumni. The program also provides recruiting support, workspace in its incubator, and the opportunity for companies to operate free of state taxes through the STARTUP-NY initiative.

Desjardins Capital is the private equity and venture capital arm of Mouvement des caisses Desjardins, based in Quebec, Canada. It provides growth capital, mezzanine, and select debt financing to early-stage through mature companies across industrial, manufacturing, technology, and service sectors, with emphasis on health care, life sciences, and biotechnology. The firm also supports cooperatives, including worker-owned and housing cooperatives, and network cooperatives, financing development, acquisitions, expansions, and succession plans. It primarily invests in Quebec and surrounding regions, and can finance growth, acquisitions, management buyouts, and modernization. Investments may be equity or debt, including unsecured loans, with instruments ranging from senior debt to equity, and tenures typically five to eight years for equity and three to five years for debt. The firm often takes minority stakes with board participation. It does not invest in natural resource exploration or financial services. Desjardins Capital traces its roots to 1974 and operates within the Desjardins Group.

500 Startups is a San Francisco headquartered venture capital firm that backs early-stage technology and financial services companies worldwide. It focuses on post-seed to Series A investments and provides hands-on support through a global network of accelerator programs, mentors, and resources designed to accelerate growth, product development, and go-to-market execution. The firm seeks capital-efficient startups and supports portfolio companies across multiple regions, helping them expand internationally and access strategic partners, customers, and markets. By combining early-stage funding with programmatic assistance, 500 Startups aims to build thriving ecosystems and scale companies across software, SaaS, education technology, and TMT sectors.

Four Rivers Group, established in 2006, is a San Francisco-based venture capital firm that invests in high-growth technology companies worldwide. It focuses on providing expansion capital to market-leading tech firms, with no set minimum investment size or ownership percentage. The firm often invests at the seed stage, serving as the first institutional capital for many of its portfolio companies.

DSM Venturing is the corporate venture capital arm of Royal DSM, established in 2001 and headquartered in Heerlen, Netherlands. The firm focuses on investing in start-up companies that develop innovative products and services within the life sciences sector, which encompasses both animal and human health and nutrition. Over the years, DSM Venturing has invested in more than fifty emerging companies across the United States, Europe, and Israel. Its primary objective is to generate strategic options and enhance value for DSM and its broader ecosystem while achieving sustainable venture-grade investment returns.

Baseline Ventures is an early-stage technology venture capital firm founded by Steve Anderson in the mid-2000s and based in Jackson, Wyoming. The firm focuses on bridging the funding gap between individual angel investors and institutional venture capital, providing seed capital and strategic guidance to startups across multiple technology sectors. Baseline has backed a broad portfolio of companies and supported many exits, reflecting its emphasis on helping founders reach scale and liquidity. Notable seed investments include Twitter, Instagram, and Heroku, among others that progressed to IPO or were acquired by major technology companies, illustrating Baseline’s role in nurturing ventures from concept to growth. The firm combines selective investments with active involvement to help teams navigate early growth, product development, and go-to-market challenges, aiming to turn promising ideas into lasting technology companies.

Version One Ventures is a venture capital firm based in Vancouver, British Columbia, founded in 2012. It backs mission-driven founders at the earliest stages and concentrates on consumer internet, software as a service, and mobile companies in North America. The firm focuses on building long-term partnerships with founders, providing capital and strategic guidance to help early-stage ventures reach product-market fit and scale. Its scope includes supporting companies across seed and pre-Series A rounds, with emphasis on sustainable growth, customer traction, and clear value propositions. By focusing on North American opportunities, the firm aims to back ambitious teams solving meaningful problems in technology markets.

Freestyle Capital is a California-based venture capital firm founded in 2009 that focuses on early-stage and seed technology investments across North America. The firm backs software, internet, SaaS, information technology, IoT, big data, and related tech companies, aiming to help market leaders grow while promoting diversity in the investment landscape. It operates from San Francisco with additional offices in Mill Valley and San Rafael, reflecting its regional footprint. The team leverages the experience of serial entrepreneurs to provide guidance and often seeks board representation in portfolio companies.

Real Ventures is a Canada-based early-stage venture capital firm founded in 2007 and based in Montreal. It backs early-stage Canadian technology startups and supports entrepreneurs who aim to build successful, global companies. The firm provides stage-specific guidance, mentorship, and access to networks and resources to accelerate founders' growth. By strengthening the Canadian startup ecosystem, Real Ventures helps teams with product development, go-to-market planning, and fundraising through connections to experienced operators, partners, and peers. Its active portfolio includes more than 100 companies valued at about $10 billion, illustrating its broad impact on Canada's technology landscape.