Arthur Ventures is a venture capital firm focused on early-stage technology companies, with an emphasis on B2B software and other information technology-enabled sectors. It backs startups across North America, including the United States and Canada, with a regional strength in the Great Plains and Upper Midwest and offices in Fargo and Minneapolis. The firm targets post-angel and pre-institutional rounds, participating in seed and early-stage financings and, in later stages, prefers syndication with other investors. Its investment scope covers information technology, life sciences, healthcare, and clean technologies, including software, hardware, web-based services, biotech, medical devices, biofuels, energy efficiency, and related enabling technologies. Arthur Ventures was founded in 2008.

Dakota Venture Group (DVG) is a venture capital investment fund operated by students at the University of North Dakota. Established in 2006, it holds the distinction of being the first entirely student-run venture capital fund in the United States. DVG offers students a unique opportunity to engage in all aspects of the investment process, including conducting due diligence, making final investment decisions, and negotiating deal terms. The organization focuses on investing in high-growth companies across the United States, providing a valuable experiential learning platform in the fields of venture capital and angel investing.

Founded in 2000, O'Leary Ventures is a venture capital firm based in Miami, Florida. It actively invests in seed through late-stage companies, aiming to build strategic partnerships and provide asset management services.

CIBC Capital Partners is a Toronto-based investment firm specializing in direct, fund, and mezzanine investments. It provides subordinated debt and equity to mid- and late-stage private or public companies for growth financing, acquisitions, management buyouts, and recapitalizations. The firm prefers investments in later-stage companies undergoing financial restructurings, with a focus on sectors such as Industrials, Healthcare, Biotechnology, Financials, and Technology. It typically invests CAD10-20 million ($9.81-$19.61 million) per company, based primarily in Canada, Europe, and Australia.

Germin8 Ventures is a venture capital firm investing in disruptive Food & AgTech companies globally. Established in 2017, it focuses on transformative technologies and solutions across the agriculture and food value chain.

Founded in 2015, Lewis & Clark Ventures is a St. Louis-based venture capital firm focusing on early-stage investments in B2B software and healthcare technology sectors. They aim to be a trusted partner for entrepreneurs, supporting them in scaling their businesses.

Merck & Co. is a global biopharmaceutical company based in New Jersey that discovers, develops, and markets medicines and vaccines to treat cancer, infectious diseases, autoimmune disorders, and other conditions. The company maintains a strong cancer portfolio anchored by an immuno-oncology therapy platform led by Keytruda and a growing vaccine business including Gardasil for human papillomavirus. Its research arm, Merck Research Laboratories, focuses on discovering and developing therapies for cancer and neurodegenerative diseases. Merck also markets animal health products. Through its science-driven approach, Merck aims to deliver innovative products and therapies that improve patient outcomes worldwide.

Founded in 1987, Canaan Partners is a global venture capital firm based in Menlo Park, California. With over $5 billion under management, the firm invests in early-stage technology and healthcare companies worldwide.

Founded in 2022, Generational Partners is a venture capital investment firm based in Los Angeles, California. The firm focuses on backing exceptional founders leading the revival of safety-critical industries such as aerospace, defense, energy, and manufacturing.

Founded in 2016, Rosecliff Ventures is a New York-based investment firm focusing on venture capital and private equity opportunities. It invests in technology-enabled companies across financial services, consumer goods, healthcare, and software industries, with investments ranging from $0.5 million to $10 million.

Homegrown Capital is a venture capital firm based in Brookings, South Dakota, founded in 2021. It invests in technology companies, focusing on business-to-business software, agricultural technology, and financial technology, across the Northern Plains and broader Midwest regions, including the Great Lakes and Mountain areas.

Excell Partners is a Rochester, New York-based venture capital firm that makes seed and early-stage investments across medical devices, materials, energy, biotechnology, ag-tech, imaging, information technology, and software. Supported by the state of New York as a seed fund, it operates as a not-for-profit organization but maintains a for-profit discipline by structuring investments as convertible debt with equity returns to achieve long-term self-sustainability. Founded in 2005, Excell Partners seeks to foster startup growth in its region through financing and related resources.

Aster Capital, established in 2000, is a Paris-based private equity firm focusing on early-stage investments in the renewable energy, industrial, transport, and mobility sectors. With a global presence in Paris, London, San Francisco, Tel Aviv, and Nairobi, the firm invests in companies across Europe, North America, and Africa, with a particular interest in digital and deep technology innovations within its target sectors.

Vertex Ventures is a global venture capital firm specializing in early-stage investments. With offices across the U.S., China, Israel, India, and Southeast Asia, they focus on enterprise and infrastructure companies, supporting innovative entrepreneurs with operational expertise and access to capital.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Tiger Global Management is a New York based investment firm that manages public and private market strategies to pursue technology-driven growth opportunities worldwide. Founded in 2001 by Charles (Chase) Coleman, the firm invests in leading global companies across various industries, with a particular emphasis on technology-enabled growth. In public markets it employs long/short and growth strategies, while in private markets it targets opportunities from early to late stage. The firm operates globally, including the United States, China, India, Latin America, and Eastern Europe, and works with portfolio companies across their lifecycle to drive long-term value.

Breakthrough Energy Ventures is an investor-led venture capital firm based in Kirkland, Washington, focused on climate and energy technology. It makes minority investments across seed, early, and later stages in companies delivering environmental services, climate technology, and cleantech solutions. The firm seeks scalable technologies that provide reliable, affordable power while reducing greenhouse gas emissions and supports innovations that address energy access, infrastructure, and transportation needs. Its mission emphasizes patient, impact-oriented investing to accelerate the transition to low-emission energy systems.

Vivo Capital is a global healthcare investment firm based in Palo Alto with offices in Asia. Founded in 1996, it focuses on investing in and building high-quality companies in the United States and China. The firm engages across multiple strategies, including growth equity, private equity (buyouts), venture capital, and public equity, and invests in biopharmaceuticals, medical devices, and healthcare services. With about 25 years of operation, it manages approximately 5.8 billion in assets and has participated in over 290 public and private companies worldwide. The team comprises physicians, scientists, entrepreneurs, operating executives, and industry experts, reflecting a hands-on approach to helping portfolio companies scale in major healthcare markets.

Novo Holdings is a Danish holding and investment firm managing the assets of the Novo Nordisk Foundation. Established in 1999, it invests globally in life science companies at all stages of development, with a portfolio also including equities, bonds, real estate, and infrastructure.

Founded in 1977 as a networking company, Minim delivers intelligent software to protect and improve WiFi connections. Its cloud platform powers intuitive apps and routers, helping customers manage their connected experience and privacy.

SemperVirens Venture Capital is an early-stage venture capital investment firm founded in 2018 and based in San Mateo, California. The firm focuses on investing in companies within the workforce technology, healthcare technology, and financial technology sectors, aiming to address the needs of employers. SemperVirens is recognized for its team's deep industry experience, strong relationships, and valuable insights, which support its investment strategy and foster the growth of innovative companies in these domains. As a Registered Investment Adviser, SemperVirens is committed to guiding its portfolio companies toward success in a rapidly evolving market.

Charge Ventures is a venture capital firm founded in 2015 and based in Brooklyn, New York. The firm focuses on seed and early-stage investments in a variety of sectors, including artificial intelligence, machine learning, augmented reality, virtual reality, blockchain, mobile applications, marketplaces, logistics, software as a service, direct-to-consumer healthcare, and the future of work. While it invests across the United States, Charge Ventures has a particular emphasis on opportunities in New York City and other major metropolitan areas such as Chicago, Atlanta, Boston, San Diego, and Miami.

Evolution Ventures engages in investments and strategic partnerships to build a global platform that brings together leaders, investors, and corporates.

Glynn Capital Management is a Menlo Park-based investment firm with an office in San Francisco that focuses on technology-oriented investments across private and public markets. Founded in 1974, it pursues long-term ownership in a small number of companies with strong management teams, sustainable business models, and meaningful growth potential. The firm concentrates on information technology, artificial intelligence, big data, cybersecurity, software, and fintech sectors, targeting opportunities in both private and public technology companies at early and growth stages. It emphasizes enduring relationships with portfolio companies and value creation through disciplined capital allocation and strategic support. The firm operates as an investment adviser, aligning its interests with those of its clients and portfolio companies.

Spark Capital is a venture capital firm founded in 2005 and based in San Francisco with offices in Boston and New York. It invests in startups across the United States, spanning early-stage to growth opportunities, focusing on software, internet, media, consumer products and services, fintech, and information technology. The firm backs companies across sectors such as software-as-a-service, digital media, online platforms, and technology-driven consumer products, often supporting ventures at the intersection of entertainment and technology, e-commerce, and education technology. It typically makes investments from formative rounds up to larger growth rounds, and seeks to take a board seat in portfolio companies to help guide strategy and growth. Notable investments include Twitter, Discord, Anthropic, Cruise, Niantic, Oculus, Warby Parker, and Tumblr, illustrating a history of backing influential products and teams.

Manhattan Venture Partners is a New York-based venture capital and private equity firm established in 2014, specializing in secondary investments in late-stage private technology companies and pre-IPO firms. The company has played a pivotal role in the institutionalization of the secondary market for venture-backed entities and has facilitated over $10 billion in primary and secondary investments. It stands out through its research capabilities, particularly via Manhattan Venture Research, which produces unbiased reports on private technology companies, addressing the informational challenges prevalent in the venture capital space. The firm provides a comprehensive suite of services, including direct and managed secondary investment opportunities, advisory services, and transaction facilitation, ensuring efficient and compliant processes. Manhattan Venture Partners targets well-capitalized companies with strong growth potential, primarily in sectors such as media, financial services, and information technology, leveraging its extensive experience to streamline transactions for private companies and their stakeholders.

Goodwater Capital is a California-based venture capital firm founded in 2014 that targets early-stage investments in consumer technology and related sectors, including housing, financial services, consumer products and services, healthcare, food, transportation, education, and entertainment. It backs exceptional entrepreneurs who create products and platforms that consumers love, with a focus on solving pressing problems and shaping the culture and global economy. Through its investments, Goodwater aims to enable startups capable of delivering broad, measurable improvements in billions of lives, reflecting a commitment to long-term positive impact.

Network Ventures is a Chicago-based venture capital firm founded in 2016 that focuses on providing funding to seed stage companies. The firm primarily invests in businesses within the internet and technology sectors, aiming to support early-stage companies as they develop and grow. By concentrating on these industries, Network Ventures seeks to foster innovation and facilitate the success of emerging entrepreneurs.

Founded in 2004 and based in Palo Alto, California, Uncork Capital is a venture capital firm focusing on seed-stage investments in SaaS, consumer goods, healthcare, and technology companies across the United States. The firm invests out of two funds: a $200M Seed fund and a $200M Opportunity fund for larger investments in mature portfolio companies.

Matrix is a San Francisco based venture capital firm founded in 1977 that backs early-stage companies across AI, B2B, consumer, fintech, health tech, and infrastructure. It works with product teams from idea through Series A, offering hands-on support and strategic guidance to help portfolio companies reach scale. The team comprises former founders and operators who bring practical insight to building startups. Matrix operates globally, including Matrix Partners China, which builds long-term relationships with entrepreneurs in China and abroad and invests across sectors and stages. Over its history, Matrix has backed companies that progressed to IPOs or acquisitions, reflecting a focus on durable growth and long-term value creation through close founder collaboration and a global network.

EnCap Investments L.P., established in 1988, is a Houston, Texas-based private equity firm focused on the oil and gas industry. It specializes in seed, start-up, emerging growth, and early venture investments, typically allocating between $10 million and $350 million per deal. The firm primarily invests in upstream and midstream oil and gas companies, with a particular interest in natural gas pipelines, processing facilities, and energy infrastructure projects. EnCap also considers investments in the energy transition sector. It operates from offices in Houston and Dallas, Texas.

Paladin Capital Group is a global investment firm that supports and grows innovative companies through venture, expansion, and growth capital. The firm specializes in technology, products, and services with dual use for commercial and government markets, combining financial acumen with national security and technical expertise to add value across market sectors and stages. It emphasizes active investing, offering strategic guidance, access, and relationships to portfolio companies. Paladin focuses on digital infrastructure resilience and investments in advanced technologies and solutions that monitor, manage, and defend critical infrastructure dependent on cyberspace. Headquartered in Washington, DC, it maintains offices in New York, Silicon Valley, London, and Luxembourg, enabling it to source opportunities and support global growth.

Trimble is a technology solutions company that helps field and mobile workers in businesses and government become more productive by linking workflows and asset lifecycles with location-based technology. Its offerings span surveying, construction, agriculture, fleet and asset management, public safety and mapping, and combine positioning technologies such as GPS, lasers and optics with software tailored to user needs and wireless delivery to connect the field with back-office operations. Founded in 1978 and headquartered in Sunnyvale, California, Trimble operates through three reportable segments: Architects, Engineers, Construction and Owners (AECO); Field Systems; and Transportation and Logistics, delivering software and hardware solutions to construction, logistics and related industries.

Founded in 2011, Slow Ventures is a San Francisco-based early-stage venture capital firm. It invests in innovative companies operating at the intersection of technology, science, society, and culture across various sectors such as software, biotechnology, e-commerce, fintech, and more.

Samsung Venture Investment Corporation is the corporate venture arm of Samsung Electronics, founded in 1999 and based in Seoul. It maintains a global presence with activity in innovation hubs such as the San Francisco Bay Area, Boston, London, Tel Aviv, Bangalore, Tokyo, and Beijing, and it backs emerging technology startups across Europe, Asia, and North America. The firm sources and invests in technology companies at multiple stages, from early-stage to pre-IPO, focusing on areas including semiconductors, materials, mobile services, internet, software, security, and enterprise solutions, as well as bioengineering and medical tech. Its investment approach targets companies developing AI, robotics, augmented and virtual reality, cybersecurity, 5G, next generation displays, battery technology, digital health, and insurtech, among others, to support shaping future technologies.

Crosslink Capital is a venture capital and growth equity firm founded in 1989 and based in Menlo Park, California. It focuses on private and public equity investments in technology and media sectors across the United States, supporting both early-stage and growth opportunities in enterprise and consumer technology. The firm partners with founders to back category creators and market disruptors from seed to later stages, helping portfolio companies scale and achieve strategic milestones. Crosslink maintains a diversified portfolio that includes software, digital media, internet services, and related TMT companies, with a track record of supporting companies that have achieved significant outcomes such as acquisitions or public listings.

Next47 is an independent, global venture firm backed by Siemens AG that concentrates on enterprise-focused technology companies. It makes fast decisions and shares deep conviction with the teams it backs, aiming to unleash maximum potential. The firm leverages its own global footprint and the Siemens ecosystem spanning hundreds of countries and regions to provide resources and collaboration opportunities. It invests primarily in software, infrastructure, and other information technology sectors, including enterprise AI-enabled solutions.

Founded in 1989, Charter Capital Partners is a premier investment banking firm headquartered in Grand Rapids, Michigan. It offers comprehensive investment banking services including mergers & acquisitions (buy-side and sell-side), succession planning, business valuation, and capital raise advisory services. Additionally, it operates as a Registered Investment Adviser managing venture capital funds and private investment vehicles.

Founded in 2012, The Startup Factory is an early-stage venture fund based in Durham, North Carolina. It invests seed capital in exchange for equity, providing mentorship, coaching, and access to a network of active angels and experienced founders through its three-month accelerator program.

Curaleaf is a vertically integrated cannabis operator known for quality, expertise, and reliability. It cultivates, processes, markets, and dispenses cannabis products across medical and adult-use markets in the United States.

Founded in 2019, London Impact Ventures is a venture capital firm headquartered in London. It invests across stages in disruptive technology companies with a focus on sustainability and growth.

Great North Ventures is a venture capital firm based in Maple Grove, Minnesota, founded in 2017. The firm focuses on investing in entrepreneurs who leverage breakthrough technologies to transform industries that remain reliant on analog processes. Great North Ventures primarily targets disruptive technology companies across the United States, providing essential guidance, capital, and connections from seed stage to Series B. The firm is committed to identifying promising startups regardless of their geographic location, recognizing that innovative companies are emerging beyond traditional hubs like Silicon Valley. With a foundation built by successful founders, Great North Ventures emphasizes the importance of execution and the capability of their portfolio companies.

Domain Associates is a New Jersey-based venture capital firm focused on life sciences and healthcare. Founded in 1985 and headquartered in Princeton with a second office in San Diego, the firm concentrates its investments in pharmaceuticals, specialty pharmaceuticals, and medical devices, with additional interest in biomaterials, bioinstrumentation, and diagnostics. The team brings extensive healthcare experience and has been involved in forming and growing a large number of life-sciences companies, leveraging its targeted network to support early through growth-stage ventures.

Founded in 2009 and headquartered in Detroit with an additional office in Boston, Fontinalis Partners is a venture capital firm focused on next-generation mobility solutions. It invests across stages and sizes, with a preference for taking a board seat. The firm targets technology companies in areas such as connected vehicles, data analytics, intelligent infrastructure, location-based services, and smart logistics, among others.

Tribeca Early Stage Partners is a New York-based network of financial professionals that specializes in financing, advising, and supporting early-stage FinTech companies. Established in 2014, the organization operates as a FinTech-focused venture group and has built a community of approximately 50 accredited investors. This network comprises entrepreneurs and business leaders with extensive expertise in institutional finance and technology, enabling them to provide valuable insights across various sectors, including fintech, data, insure-tech, proptech, deep tech, and science. Through their collective experience, Tribeca Early Stage Partners aims to foster innovation and growth in the evolving landscape of financial technology.

ESO Fund is a California-based venture capital investment firm founded in 2012 that provides cash advances to employees of venture-backed companies to exercise their stock options and cover related taxes. It uses a defined due diligence process and transaction protocol to evaluate and close transactions quickly, enabling leverage and tax optimization to improve ROI and provide liquidity for option holders, including those who have already exercised options. The firm focuses on technology-sector investments and operates as a registered investment adviser, managing capital across venture funds, including Fund V, with about $500 million under management.

M25 is a Chicago-based venture capital firm established in 2015 by Victor Gutwein and Mike Asem, focused on funding pre-seed and seed-stage technology startups in the Midwest. The firm supports portfolio companies across multiple industries, with a regional footprint spanning 24 Midwest cities in 11 states. Since its inception, M25 has backed more than 90 early-stage tech startups, aiming to accelerate growth and strengthen the Midwest startup ecosystem.

New Stack Ventures is an early-stage venture capital firm based in Chicago, founded in 2015. It focuses on pre-seed and seed investments, typically backing rounds from approximately $300,000 to $2 million. The firm seeks opportunities across sectors including business-to-business software, fintech, healthcare, ecommerce, legacy industrials, manufacturing, construction, and logistics.

Decacorn Capital is a Singapore-based venture capital firm established in 2016. It invests globally, focusing on tech-led disruptive innovations across sectors such as artificial intelligence, aerospace, blockchain, cloud & edge computing, genomics, and robotics. The firm curates high-impact businesses with rapid adoption curves and technology-driven defensible moats, aiming to generate superior returns.

Established in 2016, Straightforward Capital is a Finnish venture capital firm focused on investing in early growth stage and mid-venture technology companies. It typically takes minority stakes in its investments.