Established in 2006, SC Launch is a non-profit corporation affiliated with South Carolina Research Authority (SCRA). It facilitates applied research, product development, and commercialization programs. SC Launch provides loans, investments, and resources to selected South Carolina-based companies participating in its program, aiming to create high-wage jobs and foster technology startups.

VentureSouth is a venture capital firm based in Greenville, South Carolina, specializing in startup and early-stage investments. The firm focuses primarily on manufacturing, logistics, and healthcare sectors, targeting opportunities in the Southeastern United States, particularly the Carolinas and surrounding areas. Since its founding, VentureSouth has developed a network of over 550 investors through various angel investment groups, making it one of the largest organizations of its kind in the country. The firm typically invests between $0.25 million and $2 million for a preferred equity stake of 15% to 35%, aiming for companies that can potentially deliver a 50% annualized rate of return within a 3-5 year timeframe. VentureSouth does not engage in common equity or debt investments, and it rarely invests in convertible debt.

Upstate Carolina Angel Network is an angel investor network based in Greenville, South Carolina, established in 2008. It comprises accredited investors who provide capital and mentorship to startup and early-stage, high-growth businesses in South Carolina and the Southeast.

Founded in 2015, Good Growth Capital is a majority women-owned venture capital firm that invests in early-stage companies focused on life sciences, green tech, hard science, and data science. The firm specializes in technology commercialization, sourcing and assessing transformative companies to generate exceptional returns.

Founderville is a $6.6mm pre-seed B2B SaaS fund. 45 Greenville, SC-based Limited Partners are funding and mentoring the next crop of Greenville, SC-based founders.

Intersouth Partners is a Durham, North Carolina–based venture capital firm founded in 1985 that concentrates on seed and early-stage investments in technology and life sciences. It seeks to be a lead or co-lead investor, often participating in the first institutional round with initial investments in the range of several hundred thousand to several million dollars and pursuing a total investment across rounds around ten to twelve million dollars. The firm emphasizes equity investments and typically seeks a board seat on portfolio companies, aiming to support growth in sectors such as software, semiconductors, communications, digital media, clean technology, security, medical devices, biopharmaceuticals, agricultural biotechnology, and biomaterials. Its geographic focus centers on the Southeast, including the Research Triangle area, Washington, DC, Atlanta, and the broader corridor from Baltimore to Florida. The firm is known for its active engagement and long-standing experience in building early-stage technology and life sciences companies.

Capital A Partners is a venture capital and private equity firm that specializes in providing growth capital, acceleration equity, and debt funding to early-stage post-revenue ventures and small profitable operating companies. Founded in August 2013 and headquartered in Charleston, South Carolina, with additional offices in New York, Silicon Valley, Stockholm, and Berlin, the firm focuses on sectors such as technology, consumer products, healthcare, materials technologies, and cleantech. Capital A Partners primarily targets investments in the southeastern and East Coast regions of the United States, as well as in Latin America and Nordic-based companies.

Wilmington Investor Network is a venture capital firm based in Wilmington, North Carolina, founded in 2004. The firm specializes in investing in early-stage companies, particularly in the technology, biotechnology, and medical device sectors. It primarily focuses on businesses located in eastern North and South Carolina, aiming to support local innovation and growth. Wilmington Investor Network typically invests between $0.2 million and $0.5 million in individual investment rounds, leveraging the collective resources and expertise of its network of angel investors to foster the development of promising startups in its target industries.

Founded in 2017, IAG Capital Partners is a venture capital firm based in Charleston, South Carolina. It invests in seed to series C rounds across various stages and structures.

Founded in 2019, Healthcare Venture Partners is a venture capital firm based in Charleston, South Carolina. It focuses on investing in healthcare, digital health, health technology, information technology, and life science sectors.

Munich Re Ventures is the venture capital arm of Munich Re, a leading global reinsurance and risk solutions provider. It is an early-stage investor that is stage-agnostic with a preference for Series A and B and growth capital, investing in startups developing technologies at the intersection of risk and business models. The firm targets areas such as insurtech, climate tech, cybersecurity and privacy, health tech, and built world, as well as digital health and mobility, seeking to back companies that transform risk transfer and risk management. It works closely with Munich Re Group businesses worldwide to fund and partner with emerging companies, guided by strategic objectives of the parent company and the broader insurance industry, and it manages over a billion dollars in assets.

Founded in 2013, Autotech Ventures is a venture capital firm based in Menlo Park, California. It manages over $400 million to invest in startups innovating in connected, autonomous, shared, and electrified vehicles, as well as related mobility services. The firm provides capital, industry contacts, market intelligence, talent recruitment support, and fundraising assistance to its portfolio companies.

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies and create long-term value. Its activities span sectors such as healthcare, logistics, software, energy, manufacturing, enterprise IT, and life sciences, with a focus on supporting early-stage and growth opportunities in the United States and beyond.

Second Century Ventures is a Chicago-based venture capital firm focused on real estate technology and technology-enabled real estate businesses. It is fully capitalized by the National Association of Realtors, leveraging the resources and industry reach of a national trade organization. The firm backs early- and mid-stage companies operating in real estate tech, software-as-a-service, data analytics, fintech, digital media, and related business services. It pursues opportunities across North America, Europe, and the Middle East, supporting portfolio companies through strategic guidance and industry connections.

Evok Innovations is a Vancouver-based venture capital firm founded in 2015 that focuses on cleantech and accelerating the energy transition. It invests across North America in early-stage decarbonization technologies, including carbon management, clean fuels, electrification, and critical minerals.

Ulu Ventures is a Palo Alto, California-based seed and early-stage venture capital firm that backs technology-driven startups across the United States. Founded in 2008, it focuses on internet-enabled consumer and business services and a broad range of sectors including EdTech, FinTech, healthcare, sustainability, enterprise IT, SaaS, IoT, digital media, mobile, agtech, and marketplaces. The firm emphasizes backing diverse entrepreneurial teams and typically engages in co-investments with other investors to pursue meaningful exits. It is described as the first Latina-led venture fund in Silicon Valley and is among the larger seed-focused vehicles in the region.

Founded in Atlanta in 2007, BIP Ventures is one of the largest and most active venture capital firms in the Southeast US. It focuses on investing in extraordinary founders leading B2B software and tech-enabled service businesses at various stages of maturity across North America.

Founded in 2017, SeedFunders is a venture capital firm specializing in pre-seed and early-stage investments. Based in St. Petersburg, Florida, they focus on investing in technology startups across various sectors throughout the state.

Ben Franklin Technology Partners of Southeastern Pennsylvania is a technology-focused capital provider based in Philadelphia, founded in 1982 to advance the region's technology community. The organization funds and supports technology companies across Pennsylvania, especially in information technology, health, and physical sciences, investing substantial capital in early-stage and established ventures. It has invested over 170 million dollars in more than 1,750 regional technology companies and has launched university-industry partnerships to translate scientific discoveries into commercial products, while seeding regional initiatives that strengthen the entrepreneurial ecosystem and create jobs.

Founded in 1986, Morningside Group is a venture capital firm based in the greater Boston area. It invests in companies with innovative science and technology across life sciences, digital health, AI, materials, and technology sectors.

Founded in 1999, Grayhawk Capital is a venture capital firm based in Scottsdale, Arizona. It invests in early and growth-stage companies across various sectors, including software as a service, cloud computing, cybersecurity, enterprise software, fintech, healthcare IT, and information technology.

Topmark Partners is a venture capital firm based in Tampa, Florida, founded in 1999. Originally established as Stonehenge Growth Equity Partners, the firm spun out from Stonehenge Capital Company and later rebranded itself as Topmark Partners. The firm focuses on investing in technology-enabled businesses, targeting growth-stage companies with the potential for rapid expansion. Leveraging a strong network of relationships, particularly in Florida and the Southeast, Topmark Partners actively seeks to collaborate with entrepreneurs to drive success. The firm's investment strategy is supported by a rich history in growth equity investment, allowing it to play a pivotal role in leading investments and identifying talent for its portfolio companies.

Verizon Communications is a global broadband and telecommunications company that provides communications, information, and entertainment products and services to consumers, businesses, and government participants worldwide. Its Consumer segment offers wireless service plans, mobile devices, home Internet, video, and voice services, as well as wireless-enabled connected devices. The Business segment delivers network connectivity, private networking, cloud and software-defined networking, Internet protocol-based voice, unified communications, collaboration tools, and security and managed services, along with installation and support. Verizon maintains a nationwide wireless network, provides fixed broadband through fiber, and sells network access to mobile virtual network operators. The company serves mass market, business, government, and wholesale customers, and pursues partnerships across devices and services. Headquartered in New York, Verizon also operates a venture arm that invests in early-stage technologies to accelerate adoption within its ecosystem, and participates in philanthropic programs focused on education and community welfare.

Tao Capital Partners is a venture capital firm based in San Francisco, California, founded in 2002. The firm focuses on investing in sectors such as technology, transportation, healthcare, education, and sustainable food, with an emphasis on businesses that create a positive social and environmental impact. Tao Capital Partners actively supports companies throughout various stages of their development, aiming to foster growth and innovation in its portfolio. The firm also explores opportunities in alternative energy, agriculture, consumer products, real estate, and hospitality, demonstrating a broad approach to investment in sustainable and impactful industries.

Harbert Management is a privately owned investment management firm focused on alternative asset classes, with headquarters in Birmingham, Alabama, and offices across the United States and Europe. Established in 1993, it manages investments across private equity, venture capital, real estate, mezzanine debt, and related strategies. The firm targets value-enhancement real estate through its US Real Estate and European Real Estate platforms and serves a broad client base including foundations and endowments, funds of funds, pension funds, financial institutions, insurance companies, family offices, and high-net-worth individuals. It operates through dedicated investment teams in multiple cities to source and analyze opportunities, and its structure includes subsidiaries such as a venture capital affiliate. The firm emphasizes disciplined, principle-based investing and a global reach to access diverse markets and opportunities.

Established in 1973, Johnson & Johnson Innovation facilitates early-stage innovation through strategic partnerships. It connects potential collaborators with resources to advance transformative science and technology across pharmaceuticals, medical devices, and consumer healthcare sectors.

Founded in 2017, Stout Street Capital is a Denver-based venture capital firm investing in early-stage technology companies. They focus on sectors such as software, fintech, advanced materials, robotics, and artificial intelligence, with an emphasis on underserved markets, particularly the Rocky Mountain region.

Qualcomm Ventures is the corporate venture capital arm of Qualcomm Incorporated, established in 2000. As a global investor, it targets early‑stage technology companies across the wireless ecosystem and related fields, including mobile, AI, IoT, cybersecurity, cloud, AR/VR, robotics, healthcare, and smart infrastructure. Qualcomm Ventures leverages Qualcomm’s resources, relationships, and technical expertise to help portfolio companies grow. The firm oversees a portfolio of more than 150 active companies and has supported numerous exits exceeding a billion dollars, reflecting its alignment with Qualcomm’s core products and strategic markets.

Founded in 2004, New York Angels is one of the largest and most active angel investment organizations. It is a membership group of over 110 active investors, focusing on early-stage technology companies. The group invests $100,000 to $1 million per deal, with a goal to close investments within two months.

Seae Ventures, established in 2019 and headquartered in Boston, Massachusetts, is a venture capital firm specializing in early-stage and growth capital investments. The firm focuses on healthcare technology and services, with a commitment to investing in minority and women-owned companies, particularly those led by women and BIPOC individuals. Seae Ventures aims to generate financial returns by supporting entrepreneurs who deliver superior value, targeting sectors such as women's health, mental health, information technology, and personalized medicine, with a focus on benefiting traditionally underserved and vulnerable populations.

Gruhas is a venture capital firm established in 2021 and based in Bangalore, India. The firm focuses on investing in early-stage startups and teams that are driving advancements in technology and innovation. Gruhas targets a diverse range of sectors, including property technology, climate solutions, content creation, consumer products, clean technology, media, and entertainment. By partnering with founders in these fields, the firm aims to support the development of transformative ideas and businesses that can make a significant impact in their respective industries.

Greenspring Associates, established in 2000, is a global investment firm headquartered in the United States. It specializes in fund of funds management, offering commingled funds and customized partnership solutions to a diverse range of international clients. The firm invests in established and emerging venture capital fund managers, early and growth-stage venture-backed companies, and secondary venture capital fund and direct investments. With over $7.3 billion in committed capital, Greenspring's dedicated team combines extensive expertise in both venture fund and direct investments.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Founded in 2016, G2 Venture Partners is a venture capital firm investing in emerging technology companies that digitize traditional industries. It focuses on sectors such as transportation, energy, agriculture, manufacturing, and logistics, aiming to drive market transformations while aligning purpose with profit.

Founded in 1987, Canaan Partners is a global venture capital firm based in Menlo Park, California. With over $5 billion under management, the firm invests in early-stage technology and healthcare companies worldwide.

IDEA Fund Partners, established in 2007, is a Chapel Hill, North Carolina-based venture capital firm. It specializes in early-stage investments, focusing on technology-driven companies in the Southeast region of the United States. The firm's investment focus includes sectors such as technology, software, automation, big data, and healthcare. IDEA Fund Partners is known for its experience and active approach, supporting entrepreneurs who are innovating in industries at the early stages of digital transformation, with a particular emphasis on underserved markets.

TechOperators is a venture capital and private equity firm based in Atlanta, founded in 2008. It targets B2B software startups across the Southeast United States, with a focus on cybersecurity, enterprise productivity, cloud computing, and IT infrastructure. The firm invests in early- and growth-stage opportunities and provides strategic, operational, and networking support to its portfolio companies to drive growth and transformation.

Greycroft is a venture capital firm that concentrates on technology start-ups, with a focus on the internet and mobile markets. It operates from offices in New York and Los Angeles, and uses its media and technology industry connections to help portfolio companies gain visibility, build strategic relationships, bring products to market, and grow successful businesses. Founded in 2006, Greycroft has invested in more than 200 companies across sectors such as consumer internet, financial technology, healthcare, and enterprise software, and manages over $1 billion in capital. The firm emphasizes early-stage investing and collaborates with entrepreneurs to support growth, while pursuing diversity initiatives including a diversity term sheet rider.

Lerer Hippeau is a seed-stage venture capital firm based in New York City, founded in 2010. It invests early in a wide range of sectors and provides hands-on support to founders as they build companies, drawing on operating experience. The firm has backed a broad portfolio across consumer and enterprise startups, including Allbirds, Guideline, MIRROR, K Health, ZenBusiness, Thrive, and Blockdaemon.

Founded in 2018, Town Hall Ventures is a New York-based investment firm dedicated to transforming the U.S. healthcare market through technology. It invests in and supports visionary entrepreneurs focused on improving care delivery and health outcomes for underserved populations.

Boston Harbor Angels is an angel investment group based in Boston, Massachusetts, established in 2004. Composed of experienced business leaders, the group focuses on investing in high-growth, early-stage companies across various sectors, including life sciences, information technology, consumer products, and clean technologies. The organization typically invests in companies seeking between $250,000 and $1.5 million, emphasizing those nearing commercialization with a clear competitive advantage. Boston Harbor Angels aims to partner with entrepreneurs who are open to guidance while demonstrating the ambition and capability to drive their businesses towards success. The group collaborates in the due diligence process, with each member making individual investment decisions. They receive numerous business proposals each month, from which they carefully select a few for presentations, ultimately inviting the most promising companies to present to the entire group for potential investment discussions.

AltaIR Capital is a venture capital firm based in San Francisco, founded in 2005. It supports startups across early and growth stages in sectors such as productivity tools, future of work, software as a service, fintech, insurtech, artificial intelligence, and digital health, seeking disruptive ideas with strong return potential. The firm emphasizes backing portfolio companies that become key players in the startup ecosystem, including prominent incubator graduates and promising teams.

Wind Point Advisors, LLC is a private equity and venture capital firm specializing in leveraged buyouts, recapitalizations, industry consolidations, growth capital, and expansion capital investments in middle market companies. It also seeks to invest in corporate divestitures or family-held businesses and seek add-on acquisitions. The firm does not seek to invest in companies in real estate, retail or restaurants sectors. It prefers to invest in business services, packaging, consumer products, healthcare, transportation, logistics and route-based businesses, media and communications, food and tobacco products, and industrial products sectors based in the United States. The firm seeks to invest between $15 million and $150 million in companies with revenues between $50 million and $300 million, enterprise values between $100 million and $500 million, and a minimum EBITDA of $8 million. It prefers to take a majority stake. It is typically the control investor in each of its portfolio companies. Wind Point Partners was founded in 1984 and is based in Chicago, Illinois.

40 North Ventures is an early-to-growth stage venture capital fund under 40 North, specializing in technologies within the industrial sector. The company focuses on supporting businesses to become more data-driven, agile, consumer-centric, and environmentally sustainable. Through strategic investments, 40 North Ventures aims to drive innovation and growth in the industrial technology space, helping companies adapt to the evolving market landscape and meet the demands of a changing world.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Tiger Global Management is a New York based investment firm that manages public and private market strategies to pursue technology-driven growth opportunities worldwide. Founded in 2001 by Charles (Chase) Coleman, the firm invests in leading global companies across various industries, with a particular emphasis on technology-enabled growth. In public markets it employs long/short and growth strategies, while in private markets it targets opportunities from early to late stage. The firm operates globally, including the United States, China, India, Latin America, and Eastern Europe, and works with portfolio companies across their lifecycle to drive long-term value.

Spark Capital is a venture capital firm founded in 2005 and based in San Francisco with offices in Boston and New York. It invests in startups across the United States, spanning early-stage to growth opportunities, focusing on software, internet, media, consumer products and services, fintech, and information technology. The firm backs companies across sectors such as software-as-a-service, digital media, online platforms, and technology-driven consumer products, often supporting ventures at the intersection of entertainment and technology, e-commerce, and education technology. It typically makes investments from formative rounds up to larger growth rounds, and seeks to take a board seat in portfolio companies to help guide strategy and growth. Notable investments include Twitter, Discord, Anthropic, Cruise, Niantic, Oculus, Warby Parker, and Tumblr, illustrating a history of backing influential products and teams.

Founded in 2015, DeepWork Capital is a Florida-based venture capital firm investing in early-stage technology and life science companies. It partners with visionary entrepreneurs, providing active support to portfolio companies.

Established by Florida legislation in 2008, this fund aims to provide venture capital to emerging companies in Florida, focusing on sectors such as life sciences, information technology, and advanced manufacturing. It seeks to leverage additional resources, foster relationships with experienced entrepreneurs, and strengthen the early-stage finance ecosystem in Florida.

Founded in Tampa, Florida, Tampa Bay Ventures aims to foster a thriving startup ecosystem within the Tampa Bay region by supporting early-stage technology ventures.