West Virginia Jobs Investment Trust is a public venture capital organization based in Charleston, West Virginia. Established in 1992, it finances eligible businesses to support economic growth and job creation in the state. The organization invests across company stages—early, later, and mature—seeking to back growth in information technology, SaaS, and clean-tech sectors while maintaining financial returns commensurate with risk. It provides equity investments rather than grants or loans.
Mountain State Capital is a venture capital firm that funds seed and early-stage technology companies in the Appalachian region of the United States, including West Virginia, Pennsylvania, Ohio, Maryland, Virginia, Kentucky, Tennessee, and North Carolina. Founded in 2019, it is headquartered in Morgantown, West Virginia, with an office in Pittsburgh, Pennsylvania. The firm provides early-stage capital to high-growth companies across technology and related sectors, with typical investments of $250,000 to $500,000 per portfolio company.
Optum is a UnitedHealth Group company dedicated to making healthcare easier, more affordable, and more connected. It serves individuals, families, providers, employers, and health plans by coordinating care across clinics, at‑home settings, and online, and by offering medications, healthcare financial services, guidance, and technology to support health plan providers and care teams. Optum aims to improve efficiency, lower medication costs, and tailor care through prevention and data‑driven insights, helping more than 120 million people access medical care. The organization emphasizes streamlined scheduling and billing, patient portals, and tools that connect people, places, and ideas across the healthcare ecosystem to enhance access, outcomes, and navigation of the system.
Initialized Capital is a San Francisco-based early-stage venture capital firm focused on seed investments in technology companies. Founded around 2012, it manages more than five core funds and has six investing partners, with over $3.2 billion under management. Its portfolio companies have generated more than $200 billion in aggregate market value to date.
Seyen Capital is a venture capital firm based in Chicago that concentrates on growth-stage information technology, software, and healthcare-related opportunities, including digital health and telehealth, primarily within the United States. The firm typically invests between five and fifteen million dollars, often serving as lead or co-lead investor and taking a seat on portfolio company boards. It favors management-led teams and seeks to back companies that have an established product and initial customers, supporting growth through strategic guidance and access to capital markets. The investment program covers a broad geographic footprint across major U.S. cities, with a focus on firms outside traditional hubs. Founded in 2007, Seyen Capital aims to help portfolio companies scale through operational development and strategic initiatives.
OCA Ventures is a Chicago-based venture capital firm established in 1999 that focuses on early-stage technology investments in the United States and Canada. It backs companies in software, fintech, digital health, consumer software, and enterprise software, with a preference for scalable technology-enabled businesses in information technology and related sectors. The firm seeks to partner with startups in the United States and Canada, supporting growth in sectors such as software, digital health, fintech, and business services through early-stage funding.
Transformation Capital is a growth and expansion investment firm based in Boston, Massachusetts, focused on healthcare companies across the United States. Founded in 2016, the firm operates as a registered investment adviser and seeks to support growth-stage healthcare businesses with strategic guidance and capital to accelerate scale and development.
Sound Ventures is a venture capital firm based in Los Angeles, California, founded in 2015. The firm backs early- and mid-stage technology companies and operates as a registered investment adviser. It pursues a hands-on approach, partnering with founders to scale ventures, achieve product-market fit, and accelerate growth by leveraging industry insights and networks. Sound Ventures also manages funds focused on future technologies, including an AI-focused fund, to identify emerging talent and opportunities. The team brings experience across media and tech to support portfolio companies and to shape strategic narratives that drive momentum.
Oak HC/FT is a Stamford, Connecticut-based venture and growth equity investment firm that concentrates on healthcare information services and financial services technology. The firm aims to drive transformation in these industries by offering strategic counsel, board-level participation, and access to an extensive network of industry leaders. As a full-stack investor, Oak HC/FT supports portfolio companies across their lifecycle to foster long-term growth and address industry challenges such as value-based care, payment system improvements, cost reduction, and improved patient outcomes.
Hamilton Ventures is a seed-stage venture capital firm comprised of former real estate CXOs, entrepreneurs, and financiers. Real estate and technology are at an inflection point, with AI, machine learning, data and analytics, and software-as-a-service poised for wide deployment in real estate. The firm aims to provide strategic guidance and capital to proptech founders commercializing such technologies and to help them succeed. Its members have backgrounds at SitusAMC, CoStar, Stewart Title, Freddie Mac, Access Point Financial, Goldman Sachs, Credit Suisse, and the United States Congress.
Twenty Five Ventures is a venture capital firm founded in 2020 and based in San Mateo, California. It concentrates on real estate technology, property technology, and financial infrastructure, investing in seed and series-stage companies. The firm also provides consultancy services to startups in the real estate technology space.
Founded in 2011, Panacea Capital Advisors is an actively involved investor and strategic advisor with decades of experience in capital investment, fund raising, corporate development, and transaction structuring. They collaborate with entrepreneurs, management teams, investors, and partners to generate creative solutions.
Innovation Works is a Pittsburgh-based nonprofit economic development organization founded in 1988 to foster growth of early-stage technology startups in Southwestern Pennsylvania. It provides funding, mentorship, and programs across software, robotics, hardware, and life sciences, and supports manufacturers in adopting new technologies. As an affiliate of Ben Franklin Technology Partners, it combines resources with regional partners to build an innovation ecosystem, offering accelerator programs such as AlphaLab Robotics Factory and connections to investors and industry experts. Through its programs, Innovation Works aims to create jobs and drive regional prosperity by helping startups scale from seed stage to follow-on funding.
XYZ Venture Capital is an early-stage venture capital firm based in San Francisco that invests in startups operating in financial services, fintech, insurtech, information technology, big data, the internet of things, mobile and software as a service. The firm emphasizes long-term partnerships with founders, providing expertise across fundraising, go-to-market strategies, product development, and sales to help portfolio companies accelerate growth. By applying independent conviction and deep domain knowledge, XYZ Venture Capital supports early-stage companies in building scalable businesses and navigating strategic challenges in rapidly evolving sectors.
Garuda Ventures is a venture capital firm based in California, founded in 2018, that concentrates on pre-seed and seed investments with a B2B, fintech, commerce, infrastructure, security, API, and climate focus. As a first-check fund, it often serves as a founder’s initial believer and leads early rounds, typically investing in the range of $500K to $1.5M. The firm emphasizes a partnership-driven approach, providing strategic guidance on operations, sales, fundraising, and portfolio company development to help early-stage startups reach category-defining growth. The team, led by general partners Rishi Taparia and Arpan Punyani, supports portfolio companies with deep operating expertise and industry insight. Notable investments span across sectors, including Foundry Robotics, Mirai, Adora, and Arkero. Garuda aims to back innovative companies at the earliest stages, helping them establish market position and scale.
GTMfund is a venture capital firm founded in 2020 and based in Scottsdale, Arizona, that focuses on early-stage investments in B2B SaaS companies. The firm leverages a large network of go-to-market professionals—hundreds of revenue leaders and GTM executives—to conduct due diligence and provide strategic support. It offers portfolio companies hands-on GTM resources, including revenue playbooks, talent sourcing, and distribution assistance, to accelerate growth from product development through scale. GTMfund maintains an active portfolio of more than 120 companies and engages with founders through ongoing operational support, backed by strong collaboration with other venture firms. It also runs GTMnow, a media site delivering insights, interviews, and news related to scaling and investing in technology businesses.
Goodwater Capital is a San Francisco Bay Area–based consumer technology investment firm that backs consumer technology and fintech innovators globally, from Series A to IPO. It uses software-enabled, data-driven approaches to identify opportunities and to measurably improve lives across housing, healthcare, food delivery, financial services, education, entertainment and transportation. The firm provides entrepreneurs with detailed data, mentorship, startup curricula and strategic advice to scale from early traction to millions of customers and billions of dollars in value. Its portfolio spans housing, healthcare, fintech, ecommerce and consumer services, with measurable impact across millions of lives and large-scale transaction activity.
Alumni Ventures is a venture capital firm founded in 2014 and based in Manchester, New Hampshire. It connects accredited individual investors with startup deals and co-invests alongside established venture capital firms across multiple stages, from seed to growth. The firm provides access to diversified portfolios through funds, syndicates, and investing clubs, supported by a large network of community members and individual investors. It invests across sectors and geographies, with a focus on transparency and due diligence in collaborative investments with leading firms such as Andreessen Horowitz, Sequoia, and Y Combinator. Alumni Ventures operates internationally with offices in New York, Boston, Menlo Park, Chicago, London, and Tokyo and has raised substantial capital to back founders with strategic capital and resources.
Select Venture Partners is an early-stage venture capital firm based in Fredericksburg, Virginia, founded in 2014, that provides capital and hands-on support to software startups. The firm focuses on cloud services, enterprise software, SaaS, mobile, data analytics, and e-commerce companies at seed to pre-Series A stages, with a U.S. footprint that includes the East Coast and the Intermountain West. The team combines funding with practical operating experience, leveraging a track record of successful exits to help portfolio companies move from early product development toward scalable growth. The firm seeks to bridge the gap between seed capital and later-stage investment by offering strategic guidance, network access, and operational help tailored to early-stage software ventures.
RRE Ventures is a New York-based venture capital firm established in 1994 that backs seed to early-stage technology companies. The firm invests across sectors including artificial intelligence, fintech, enterprise software, hardware, healthcare, media, robotics, crypto, and space, with activity in the United States and Canada. It operates with a boutique model centered on deep founder relationships, experienced guidance, and long-term backing through all growth stages. RRE emphasizes using artificial intelligence to enhance due diligence and portfolio management. The firm targets both financial services and technology companies and has assets under management in the billions, reflecting its extensive experience and standing as a registered investment adviser.
Wasabi Ventures is a venture capital, incubator, and consulting firm that focuses on building and advising early-stage technology companies. In the past decade, it has built, financed, and advised more than 200 startups. It operates offices in four locations—San Mateo, California; Manchester, New Hampshire; Baltimore, Maryland; and Donetsk, Ukraine—reflecting a global footprint with its headquarters in San Mateo. The firm targets mobile, software as a service, and artificial intelligence sectors and provides incubator and advisory services to early-stage ventures. Its team covers core startup functions including technology development, sales, product marketing, fundraising, and business planning, with partners able to allocate additional staff for specialized needs. By combining funding, hands-on development support, and strategic guidance, Wasabi Ventures aims to help startups move from concept to scale.
Ontario Municipal Employees Retirement System is one of Canada's largest defined-benefit pension plans, serving municipal workers and related public-sector employees in Ontario. Founded in 1962 and headquartered in Toronto, OMERS manages a diversified global portfolio across public equities, fixed income, real estate, infrastructure, and private markets. It operates through multiple investment arms that include private equity, growth equity, venture, and infrastructure, to deploy capital aligned with long-term retirement promises. OMERS emphasizes disciplined governance, risk management, and environmental, social, and governance considerations to generate sustainable value and support broad economic growth for its members and communities.
The Startup Factory is an accelerator based in Durham, North Carolina, founded in 2012. It supports early-stage startups by providing seed capital in exchange for equity and a structured three-month program of coaching, mentorship, and access to a network of experienced founders and investors. The program typically offers $50,000 in seed funding for approximately 7.5% equity, with potential follow-on funding in the form of a convertible note ranging from $20,000 to $150,000 upon successful completion. The accelerator targets startups across web, mobile, software, tourism, hospitality, and education sectors, helping ventures refine product, market fit, and growth strategy.
Itochu Corporation is a global trading company (sogo shosha) with origins dating to 1858 when linen trading began. The company conducts domestic and overseas trading and investment activities across a wide range of products, including textiles, machinery, information and communications equipment, metals, energy and oil products, general merchandise, chemicals, and provisions and food. Itochu coordinates import and export operations and has diversified interests in insurance agencies, finance, construction, real estate trading, and warehousing, as well as related services. With a worldwide network of offices and partners, Itochu connects suppliers and customers, manages risk, and supports global supply chains across multiple industries, reinforcing its role as a leading intermediary in international commerce and a diversified participant in various markets.
UnitedHealth Group is a leading healthcare and well-being company operating through UnitedHealthcare and Optum. It offers a broad suite of products and services, including health benefit plans for individuals and employers, care delivery, pharmacy care, and software, data analytics, and advisory services through Optum. The company emphasizes value-based care, innovation, and affordability, aiming to improve access to high-quality care for diverse populations. Its businesses span insurance, health services, information technology, and healthcare delivery, serving payers, providers, employers, and government programs worldwide. UnitedHealth Group leverages clinical data and AI to streamline administrative processes and clinical decision-making, with ongoing efforts to standardize workflows such as prior authorization to reduce friction for patients and providers.
Slow Ventures is a San Francisco-based generalist early-stage venture capital firm with offices in San Francisco, Boston, and New York. Founded in 2011, it invests across security, fintech, SaaS, crypto, consumer, healthcare, and the creator economy, supporting founders developing technology-driven businesses at the center of technology and on the edges of science, society, and culture. The firm emphasizes long-term growth and a conviction-driven approach, offering resources, connections, experiences, and empathy to help build resilient companies. Notable investments include Airtable, Gusto, OpenPhone, Ro, Solana, and Teamshares.
Amity Ventures is a San Francisco-based venture capital firm that supports technology founders in building category-defining businesses. The partners have invested in more than fifty companies across all growth stages, and the firm concentrates on early-stage opportunities, typically writing checks of $1-5 million in pre-seed, seed, or occasionally Series A rounds. Amity Ventures engages closely with portfolio companies, often joining boards and assisting with deals, recruiting and problem-solving to support growth. The firm focuses on information technology, mobile, cryptocurrency, and blockchain sectors, and emphasizes a people-centered approach to partnering with founders throughout the company’s journey.
Index Ventures is a global venture capital firm founded in 1996, with offices in London, San Francisco, and Geneva. It backs technology startups across stages from seed to growth in sectors including software, AI, fintech, healthcare, data, media, and consumer services. The firm provides capital and strategic support, helping teams assess business models, scale operations, and navigate financing rounds. Its broad network connects founders with investors, partners, and market opportunities to support growth across geographies. Index Ventures emphasizes long-term founder relationships and hands-on collaboration, offering guidance and resources to help companies reach global markets. It also launched Index Origin, a seed fund designed to support entrepreneurs from day one.
Tuesday Capital is a San Francisco-based venture capital firm founded in 2011 that specializes in seed and early-stage technology investments. It takes a hands-on approach, providing capital, strategic guidance, and industry connections to help portfolio companies scale. The firm supports information technology-enabled startups and has built a broad portfolio of companies, with many progressing to IPOs or acquisitions by major tech firms. Led by co-founders and partners, Tuesday Capital emphasizes founder relationships and ongoing support throughout a company's lifecycle, aiming to be a trusted partner rather than just an investor.
Foundation Capital is a Palo Alto-based venture capital firm founded in 1995 that backs early to growth-stage startups across a broad mix of sectors, including enterprise software, fintech, consumer technology, data security, and digital energy. The firm emphasizes a founder-first, conviction-based approach and provides active support, often taking board seats and guiding portfolio companies from day one. Its portfolio includes notable companies such as Lending Club, Netflix, Sunrun, AdRoll, ForgeRock, and Localytics, and it has supported numerous ventures across information technology, software, and marketing technology. With operations in the United States and selective international exposure, Foundation Capital funds entrepreneurs through multiple rounds, aiming to help companies scale and achieve IPOs or acquisitions. The team is composed of former entrepreneurs who leverage hands-on experience to help builders execute growth strategies, navigate markets, and build durable businesses.
CSC Upshot Ventures is a Palo Alto-based venture capital firm founded in 2015 that focuses on seed and early-stage technology companies. It targets sectors including enterprise software, artificial intelligence, healthcare, financial technology, and marketplaces, and pursues a global investment reach across the United States, Canada, Europe, South America, and Africa. The firm collaborates with AngelList to support founders and builds a network to connect capital with innovation.
BoxGroup is a New York-based venture capital firm that supports early-stage technology companies through pre-seed to Series A rounds. Founded in 2009, the firm invests across consumer, enterprise, fintech, healthcare, life sciences, marketplaces, and software sectors, seeking teams capable of leading category-defining movements. Although it makes opportunities globally, BoxGroup maintains a focus on New York City, Silicon Valley, and Los Angeles, with geography not a constraint. The firm generally takes a hands-off approach to governance, not demanding board seats, and aims to back entrepreneurs at the start of meaningful market shifts. Through its early-stage investments, BoxGroup looks for disruptive technology, health and biotech, SaaS, e-commerce, and related areas with potential for scale. The objective is to support ambitious founders with visions to create the next generation of market leaders.
Great North Ventures is a venture capital firm based in Maple Grove, Minnesota, founded in 2017. Built by successful founders, it backs early-stage startups across the United States that apply breakthrough technologies to modernize industries still dominated by analog processes. The firm makes seed to Series B investments, offering guidance, capital, and connections to help portfolio companies scale. It seeks opportunities beyond Silicon Valley and prioritizes founders with proven execution. Core focus areas include vertical AI, embedded finance, fintech infrastructure, industry-specific automation, information technology, and real estate technology. Through multiple funds, it actively partners with startups to accelerate growth, with typical checks ranging from 0.25 to 0.75 million.
EnCap Investments is a Houston-based private equity firm that focuses on energy, including upstream and midstream oil and gas, natural gas pipelines, gathering, processing, storage, and related infrastructure. It provides growth capital for reserve acquisitions and drilling projects and pursues opportunities across the United States, Canada, and Mexico, with a Dallas-area emphasis. Founded in 1988, EnCap supports independent energy companies through long-term partnerships, drawing on expertise in finance, operations, and strategic development while incorporating ESG considerations and the energy transition into its investment approach.
FINTOP Capital is a venture capital firm based in Nashville, Tennessee, founded in 2016. It concentrates on investing in B2B software-as-a-service and software companies in the FinTech space, with a focus on B2B FinTech and vertical SaaS platforms that have a proven product, real revenues, and leadership drawn from the industries they serve. The firm also maintains offices in Hoboken, New Jersey, and St. Louis, Missouri.
U.S. Venture Partners is a Menlo Park, California-based venture capital firm that backs early-stage technology and healthcare companies. With more than thirty years of operation, it helps entrepreneurs transform ideas into growth companies, focusing on enterprise software, IT security, consumer internet, mobile, e-commerce, and IT-enabled healthcare services. The firm targets startups in information technology and healthcare that can scale in the United States, and in some cases Israel, and it emphasizes collaboration with teams that include former entrepreneurs, technologists, executives, and industry experts. USVP invests in software, healthcare, cybersecurity, and related technology-enabled sectors, supporting portfolio companies through early development and scale-up.
Quiet Capital is a venture capital firm based in San Francisco, founded in 2017. It invests across a broad range of sectors including enterprise software, consumer, fintech, marketplaces, deep tech, healthcare, and crypto, seeking founders and teams with differentiated products and scalable models.
Liquid 2 Ventures is a San Francisco-based venture capital firm founded in 2015 by Joe Montana, Mike Miller, and Michael Ma. It provides seed- and early-stage capital to technology startups, occasionally supporting later rounds such as Series B, and often invests alongside co-investors. The firm emphasizes strategic introductions and hands-on guidance to help portfolio companies scale, with a focus on software, TMT, and other technology sectors. By partnering with founders and other investors, Liquid 2 Ventures aims to align capital with long-term company growth.
FundersClub is an online venture capital platform that connects accredited investors with a diversified portfolio of vetted startups. Founded in 2012 and based in San Francisco, California, the company focuses on seed and early-stage investments in technology and technology-enabled startups. It operates a globally sourced network and rigorous vetting process to streamline access to early venture opportunities typically unavailable to individual investors, while providing hands-on support to portfolio companies. By combining software-driven processes with human due diligence, FundersClub seeks to deliver returns for investors and help founders accelerate growth. The platform emphasizes transparent, scalable participation in venture capital rather than traditional fund structures.
New Stack Ventures is an early-stage venture capital firm based in Chicago, Illinois. It primarily invests in pre-seed and seed startups, typically deploying from hundreds of thousands to a few million dollars. The firm targets sectors such as AI, B2B software-as-a-service, fintech, healthcare, ecommerce, legacy industrials, manufacturing, construction, and logistics. It emphasizes backing founders outside traditional Silicon Valley networks and provides more than capital by leveraging a partner network to facilitate customer and partner introductions and strategic guidance. The firm looks to fund companies building essential infrastructure and applying AI to improve efficiency in large, underserved markets.
M25 is a Chicago-based venture capital firm focused on the Midwest, founded in 2015 by Victor Gutwein and Mike Asem. It invests in pre-seed and seed-stage technology startups headquartered in the Midwest and has backed a large portfolio across multiple cities and states in the region. The firm emphasizes an analytical approach and collaborative partnership with founders to support growth, aiming to be a key participant in the Midwest startup ecosystem across various technology sectors.
Green D Ventures is a venture capital firm based in Bedford, New Hampshire, focused on early-stage technology and service companies, with a preference for Dartmouth alumni ventures. It participates in Series A rounds and convertible notes with caps, typically making investments from $50,000 to $500,000. The firm plans to deploy capital in 15 to 25 deals per year and co-invests with top-tier venture funds across a broad range of industries, stages, and geographies. It does not lead rounds, price rounds, or take board seats, aiming to be valuable and frictionless for portfolio companies. The firm leverages the Dartmouth alumni entrepreneurial network and Dartmouth-led ventures.
Crimson Hill is a growth equity firm focused on technology-based companies in the energy and advanced materials sectors. Founded in 2012 and based in Gastonia, North Carolina, it provides growth capital across stages, blending venture and private equity approaches to support emerging businesses with proven technologies and clear pathways to significant revenue growth. Portfolio companies seek measurable improvements in efficiency, reliability, and cost competitiveness in established markets. The firm concentrates investment activity in the Appalachian Mountain, Ohio Valley, and Great Lakes regions in the United States.
Quotidian Ventures is a New York City based venture capital firm that backs seed to early-stage technology companies, focusing on software-enabled businesses that transform large industries. It prioritizes opportunities in digital entertainment, advertising, mobile, e-commerce, and digital publishing, and tends to favor startups located in New York City or Latin America, while remaining open to strong companies globally. The firm supports founders with initial capital and strategic guidance to help them develop products and scale.
Upstage Ventures is a New York-based venture capital firm founded in 2010 and led by Mark Wachen. It provides investment and advisory services to early-stage consumer internet and interactive marketing companies, supporting digital commerce and related initiatives. Its portfolio includes SeatGeek, YouNow, Veritonic, TVision, Bedly, Vengo, OrderGroove, and Rally.
Rugged Ventures is a New York-based venture capital firm that invests in seed-stage companies. Founded in 2001 by Dave Lerner, it targets opportunities in information technology, sales, marketing, finance, advertising, and mobile sectors.
NCT Ventures is a Columbus, Ohio-based venture capital firm that focuses on the Midwest. It backs seed and early-stage technology companies that disrupt major industries, with typical investments of $250,000 to $1 million in early rounds and up to $5 million in growth rounds. The firm provides hands-on operational support to help entrepreneurs scale, drawing on more than two decades of experience. NCT Ventures has historically targeted sectors such as healthcare, adtech, advanced manufacturing, ecommerce, and information technology, and aims to back early-stage technology-based companies across the United States.
JWI Capital is a private equity and venture capital firm based in Ohio, founded in 2009. It makes acquisitions, management buyouts, and growth equity investments across manufacturing, process industries, services, defense, aerospace, general industrials, energy, infrastructure, transportation, and packaging, and also acquires related outsourced business services or distribution companies. The firm targets companies generating roughly $5 million to $50 million in revenue and EBITDA up to $5 million, with a preference for minority stakes but also pursuing control investments, typically within a 300-mile radius of Northeast Ohio. Its portfolio spans metals, plastics, advanced materials, chemicals, engineered components, consumables, maintenance, and software serving its core industries.
Sequoia Capital is a venture capital firm founded in 1972 and based in Menlo Park, California. It provides capital alongside strategic guidance to a select set of companies across information technology, healthcare, manufacturing, mobile, nanotechnology, financial services, internet, energy, media, and retail, supporting them from early ideas through growth and even IPO stages. The firm emphasizes long-term partnerships, working closely with leadership teams on product development, company building, and market expansion. Sequoia pursues opportunities at seed, early, and growth stages and maintains a global reach, investing in companies across the United States and other major markets, with interests in AI and other emerging technologies.