Zimmer, Inc., operating as Zimmer Biomet, specializes in the design, manufacture, and marketing of orthopedic and dental products. The company offers a wide range of solutions, including joint replacement products for the knee, hip, and shoulder, as well as elbow and trauma devices, foot and ankle systems, and spinal solutions. Zimmer Biomet also provides dental implants and various surgical and operating room equipment, alongside biologics and sports medicine solutions. These products are aimed at helping healthcare professionals treat a variety of conditions, including arthritis and traumatic injuries, ultimately supporting patient mobility. Founded in 1927 and headquartered in Warsaw, Indiana, Zimmer Biomet operates multiple manufacturing facilities across the United States and internationally, including locations in Puerto Rico, Switzerland, and Ireland, and maintains a biologics research facility in Texas.
Paragon 28, Inc. is a medical device company specializing in products for foot and ankle surgery. Incorporated in 2010 and based in Englewood, Colorado, with an additional headquarters in Dublin, Ireland, the company offers a comprehensive range of surgical solutions, including plates, screws, allograft bone systems, and interference screws for various orthopedic procedures. Its product portfolio features advanced systems such as the PHANTOM Lapidus Intramedullary Nail for arthrodesis correction, the Proximal Rotational Metatarsal Osteotomy for bunion correction, and the Paratrooper Plantar Plate Repair System for plantar plate repairs. Paragon 28 aims to meet the diverse needs of foot and ankle surgeries through its nearly 80 product systems, addressing conditions such as hallux valgus, fracture fixation, and flat foot. The company primarily generates revenue from the United States market.
OrthoGrid Systems
Acquisition in 2024
OrthoGrid specializes in developing intraoperative assessment tools aimed at enhancing orthopedic joint reconstruction and trauma procedures. The company focuses on creating anatomy-specific radiopaque grid patterns that assist orthopedic surgeons in positioning implants accurately and restoring leg length during total hip replacements, particularly via the anterior approach. OrthoGrid's portfolio includes a range of patented and patent-pending technologies designed to improve clinical outcomes by addressing critical factors such as implant positioning, limb alignment, and fracture reduction. By providing innovative tools, OrthoGrid aims to empower surgeons to make informed decisions in the operating room, ultimately enhancing patient care and alleviating joint pain.
Osteal Therapeutics
Series D in 2024
Osteal Therapeutics is a clinical-stage specialty pharmaceutical company focused on developing innovative drug and device combination products aimed at treating musculoskeletal infections. The company's therapeutics are designed to significantly reduce the mortality and morbidity associated with these infections, as well as the related healthcare costs. Osteal Therapeutics offers solutions for orthopedic infections, including those affecting infected joint prostheses, providing fast and reliable treatment options. This enables orthopedic surgeons to deliver effective care for musculoskeletal diseases, enhancing patient outcomes and addressing a critical need in the field of infection therapeutics.
OSSIS
Acquisition in 2023
OSSIS is a company focused on the development of orthopedic implants specifically designed for acetabular revisions and pelvic tumors. Utilizing advanced digital image manipulation, design software, and three-dimensional (3D) printing technology in titanium, OSSIS creates implants that provide effective anchor points for reattaching soft tissue. This innovative approach enhances the ability of medical professionals to treat their patients, improving surgical outcomes and patient care in the field of orthopedics.
Embody
Acquisition in 2023
Embody, Inc., established in 2014 and based in Norfolk, Virginia, is a regenerative medicine company specializing in the development and commercialization of implantable medical devices. Its primary focus is addressing unmet demands in soft tissue restoration and regeneration, specifically for tendon and ligament repair. Embody's innovative collagen-based microfiber implants are designed to replicate the biological and biomechanical properties of native tissue, aiming to restore pre-injury performance for a wide range of patients, including warfighters, athletes, and those suffering from sports injuries. The company employs advanced technologies such as microfluidic biofabrication and electrospinning in its product development.
Neuroone Medical Technologies
Post in 2022
NeuroOne Medical Technologies Corporation is a medical technology company based in Eden Prairie, Minnesota. It is dedicated to the development and commercialization of advanced thin film electrode technology designed for continuous electroencephalogram (cEEG) and stereoelectroencephalography (sEEG) recording. The company's focus extends to spinal cord stimulation, brain stimulation, and ablation solutions, targeting patients with conditions such as epilepsy, Parkinson’s disease, dystonia, essential tremors, and chronic pain resulting from failed back surgeries. NeuroOne aims to provide minimally invasive, high-definition solutions that enhance patient outcomes while potentially reducing procedural costs in the treatment of various neurological disorders.
A&E Medical
Acquisition in 2020
A&E Medical Corporation is a manufacturer and designer of medical devices, specializing in a range of products used in surgical procedures. The company's offerings include temporary cardiac pacing leads, high-strength sternum closure systems, stainless steel sutures, electrosurgical instruments, surgical punches, and neurosurgical scalp clips. In addition to its core product line, A&E Medical provides contract manufacturing services, including wire and cable extrusion, electro-mechanical assembly, and sterile packaging. Headquartered in Farmingdale, New Jersey, A&E Medical serves both domestic and international markets through a comprehensive distribution network. Established in 1967, the company has built a reputation for quality and innovation in the medical device industry and operates as a subsidiary of Zimmer Biomet Holdings, Inc.
Relign
Acquisition in 2020
ReLign Corporation, established in 2011 and headquartered in Cupertino, California, develops and manufactures advanced electrosurgical devices and accessories, specifically focusing on arthroscopic systems for orthopedic procedures. The company's flagship product is the ReLign Arthroscopic System, which features a reusable and sterilizable handle connected to a single umbilical cable for the precise cutting and removal of bone and soft tissue. This innovative design enables orthopedic surgeons to visualize, diagnose, and treat joint injuries effectively and painlessly, enhancing patient outcomes while maintaining cost efficiency. ReLign operates as a subsidiary of Zimmer Biomet Holdings, expanding its reach within the medical device industry.
SIG Medical
Acquisition in 2019
SIG Medical Corp. is a medical device manufacturing company based in Hershey, Pennsylvania, founded in 2016. The company specializes in developing a novel, minimally invasive surgical repair procedure for fractured ribs, offering a patented and FDA-approved rib fixation system. This system is designed to provide effective fixation, stabilization, and fusion of rib fractures and osteotomies in both normal and osteoporotic bone. By prioritizing a less costly, less time-consuming, and less painful approach, SIG Medical aims to enhance patient care while also reducing healthcare spending for payors. Their innovative devices are optimized for the operating room, allowing surgeons to perform rib repairs more efficiently and effectively.
Respondwell
Acquisition in 2016
RespondWell, LLC is a digital health company that specializes in a telerehabilitation platform designed for patients and healthcare providers, including outpatient rehabilitation clinics and senior care facilities. Founded in 2003 and based in Grand Rapids, Michigan, RespondWell offers a range of services that include prevention and rehabilitation modules, clinical content, and tools for clinicians. The platform facilitates patient engagement by allowing access to instructional videos for physical therapies, and incorporates features such as in-product rewards to enhance motivation. Additionally, it provides personalized rehabilitation programs and utilizes sensors to monitor patient performance. RespondWell, which was previously known as Respondesign, Inc., was acquired by Zimmer Biomet Holdings in October 2016.
Clinical Graphics
Acquisition in 2016
Clinical Graphics B.V., founded in 2010 and based in Delft, the Netherlands, specializes in 3D motion simulation technology aimed at informing treatment decisions for orthopedic conditions, particularly those related to the hip. The company provides a service called Move Forward, which allows orthopedic surgeons and radiologists to submit image data, including CT and MRI scans, to receive detailed 3D motion simulation reports. These reports help physicians better understand the physiological aspects of a patient's pain, enabling them to tailor treatment approaches for conditions such as dysplasia and femoroacetabular impingement. Since September 2016, Clinical Graphics operates as a subsidiary of Zimmer Biomet Holdings, enhancing its capabilities in the medical imaging sector.
CD Diagnostics
Acquisition in 2016
CD Diagnostics is developing assays for orthopaedic surgeons and rheumatologists who would like greater diagnostic confidence in joint fluid analysis. Unlike current technologies, which often yield vague and ambiguous results, CygnaSure™, our lead product, offers orthopaedic surgeons and rheumatologists a rapid, accurate and reliable diagnostic answer.
Medtech SAS
Acquisition in 2016
Medtech’s mission statement can be summarized in the following way: Their mission consists of the broader use of medical technology for the benefit of both patient and practitioner as they strive for improved overall health and well-being. Medtech designs, develops and markets a new generation of robotic assistance for the express purpose of improved surgical techniques. Their robots contribute to safer and more stable implementation of both more effective and less invasive treatment.
Compression Therapy Products
Acquisition in 2016
Compression Therapy Concepts, Inc. specializes in the production and distribution of medical products aimed at preventing deep vein thrombosis (DVT) and reducing the risk of pulmonary embolism. Established in 1999 and based in Eatontown, New Jersey, the company offers a range of products, including the VasoPress DVT system, various garment sizes for different patient needs, and necessary connector tubing. Its offerings are designed to enhance patient outcomes and minimize complications associated with DVT by integrating with care practices in acute, long-term, and home care settings. The company operates through a sales network across the United States and emphasizes cost-effective, environmentally friendly solutions in its product line.
LDR Holding
Acquisition in 2016
LDR Holding Corporation is a medical device company that specializes in developing and marketing implantable spine systems and instrumentation for both patients and surgeons. The company offers a range of spinal surgery solutions, including artificial disc systems, pedicle screw systems, cervical cages, and various implant systems designed for cervical and lumbar applications. LDR Holding also provides synthetic bone substitutes and innovative surgical technologies, such as the VerteBRIDGE product, which is tailored for specific surgical procedures. Its products are distributed in numerous countries, including Australia, Japan, and various European nations, through partnerships with surgeons and distributors. Founded in 2004 and headquartered in Austin, Texas, LDR Holding has expanded its presence internationally with additional offices in France, China, Brazil, and Germany. The company was previously known as LDR Spine USA, Inc. before rebranding following its acquisition of LDR Médical.
Cayenne Medical
Acquisition in 2016
Cayenne Medical, Inc. is a medical device company specializing in soft tissue reconstruction solutions for the knee, shoulder, and extremities. Founded in 2005 and based in Scottsdale, Arizona, the company designs and markets a range of products aimed at improving surgical outcomes in sports medicine. Its offerings include the AperFix System, which facilitates anterior cruciate ligament (ACL) reconstruction using soft tissue grafts, as well as the AperFix II Cannulated Tibial Device and the AperFix Femoral Implant for anatomical soft tissue fixation. Cayenne Medical also provides the CrossFix II System for meniscal repair, the iFix for bone-tendon fixation, and the Cayenne Mirror Partial Knee System for early-stage knee arthritis treatment. In the shoulder category, the Quattro System addresses rotator cuff and labral repairs. Cayenne Medical operates as a subsidiary of Zimmer Biomet Holdings, enhancing its capacity to deliver innovative medical solutions.
Ortho Transmission
Acquisition in 2016
Ortho Transmission has develops a skeletal implant technology.
ETEX
Acquisition in 2014
ETEX Corporation specializes in the development, manufacturing, and commercialization of calcium phosphate-based biomaterials aimed at enhancing orthopedic clinical outcomes. As a leader in bioresorbable bone substitute materials, the company is dedicated to advancing the applications of its products through innovative combinations with cells, biologics, or therapeutic agents. These solutions are designed for use in minimally invasive procedures, facilitating the repair and regeneration of bone affected by trauma or disease.
BioMet
Acquisition in 2014
Biomet, Inc., together with its subsidiaries, engages in the design, manufacture, and marketing of surgical and non-surgical products primarily used by orthopedic surgeons and other musculoskeletal medical specialists in the United States, Europe, and internationally. The company’s reconstructive products include knee, hip, shoulders, and extremity joint replacement systems, as well as dental reconstructive implants, bone cements, and accessories; autologous therapy products; and the procedure-specific instrumentation required to implant the company’s reconstructive systems. It also offers various fixation devices comprising internal and external fixation devices, craniomaxillofacial fixation systems, and electrical stimulation devices. In addition, the company supplies spinal products, which include electrical stimulation devices addressing the spine, spinal fixation systems, and orthobiologics for the spine. Further, it offers sports medicine products, softgoods and bracing products, casting materials, general surgical instruments, operating room supplies, and other surgical products. The company was founded in 1977 and is headquartered in Warsaw, Indiana. Biomet, Inc. is a subsidiary of LVB Acquisition, Inc.
Normed Medizin-Technik
Acquisition in 2013
Normed Medizin-Technik GmbH is a subsidiary of Zimmer Biomet Holdings Inc., focused on the development, manufacturing, and distribution of medical products globally. The company specializes in hand and foot surgery, offering a range of surgical products that include solutions for pediatric orthopedics and both lower and upper extremities. Normed prioritizes quality, service, and competence in its operations, aiming to enhance patient care through innovative medical solutions.
Knee Creations
Acquisition in 2013
Knee Creations is an orthopedic medical device company based in New York, New York, specializing in solutions for knee osteoarthritis. Established in 2007, the company has developed minimally invasive surgical procedures and devices aimed at treating knee pain related to chronic bone marrow lesions (BMLs). One of its key innovations is the Subchondroplasty procedure, which addresses bone defects by using a biomimetic bone void filler. Additionally, Knee Creations offers training for healthcare professionals to effectively implement these procedures in their practices. The company operates as a subsidiary of Zimmer Holdings.
Dornoch Medical Systems
Acquisition in 2012
Dornoch Medical Systems is a manufacturer based in the United States that specializes in fluid management systems. The company produces an integrated infectious fluid collection and disposal system known as transposal, which is designed for use in operating rooms and across various healthcare facilities. In addition to its core products, Dornoch Medical Systems also offers a range of fluid management accessories to support healthcare operations.
Synvasive Technology
Acquisition in 2012
Synvasive Technology, Inc. specializes in the development, manufacture, and distribution of advanced surgical cutting instruments for reconstructive orthopedic surgery. With nearly twenty years of experience, the company is recognized for its patented and proprietary technologies, including the STABLECUT® large bone surgical saw blades, which are considered the industry gold standard. By focusing on innovation and quality, Synvasive aims to enhance surgical outcomes and improve the efficiency of orthopedic procedures.
ExtraOrtho
Acquisition in 2011
ExtraOrtho, Inc. provides damage control and deformity correction solutions for surgeons, administrators, and patients. It offers XTRAFIX, an external fixation system that allows surgeons to eliminate steps, bars, and clamps. ExtraOrtho, Inc. was formerly known as QFx Technologies, Inc. and changed its name to ExtraOrtho, Inc. in May 2009. The company was founded in 2007 and is based in Memphis, Tennessee. As of November 10, 2011, ExtraOrtho, Inc. operates as a subsidiary of Zimmer Holdings, Inc.
Zfx GmbH
Acquisition in 2011
Zfx provides dentists, dental labs and milling centres with high-end applications from the entire dental process chain: from the intraoral and desktop scanner and dental shade measuring instrument through to digital axiography and CAD software to the complete solution for dental milling providers. In addition, as Zfx partner you benefit from the new and unique Zfx online platform, which allows for continues control and replacement opportunities during the entire dental production process.
Zimmer Surgical
Acquisition in 2010
Sodem Diffusion S.A., the manufacturer of SoPlus Orthopaedic Surgical Power Tools based in Geneva, Switzerland. The company will be re-named Zimmer Surgical, S.A. and will be part of Zimmer Surgical, headquartered in Dover, Ohio.
Beijing Montagne Medical Device Co.
Acquisition in 2010
Beijing Montagne Medical Device Co., Ltd. is a privately held company deals and engages in the development, production, and sale of artificial joints in China and abroad.
Abbott Spine
Acquisition in 2008
Abbott Spine, founded in 1996 and headquartered in Austin, Texas, with an international facility in Bordeaux, France, specializes in developing innovative spinal implant technologies aimed at treating spine diseases. The company focuses on creating less invasive solutions that enable surgeons to address various spinal disorders, diseases, and injuries effectively. Notable products include the InCompass Pedicle Screw System, the Pathfinder Minimally Invasive Pedicle Screw System, the Wallis Interspinous Stabilizer System (available outside the U.S.), the Ant-Cer Dynamic Cervical Plate, and the Universal Clamp. Through its advancements, Abbott Spine has established a reputation for improving surgical outcomes in spinal care.
Endius
Acquisition in 2007
Endius, founded in 1997, specializes in developing innovative products for invasive and endoscopic spine surgeries aimed at providing less traumatic and more effective solutions for patients suffering from back pain. The company's product portfolio includes the Atavi system, an atraumatic spine surgery system designed to assist surgeons in performing various lumbar spine fusion procedures, as well as the TiTLE and MDS microdebrider systems. Endius is focused on creating comprehensive spine surgery solutions to enhance surgical outcomes. The company was acquired by Zimmer Biomet Holdings, further expanding its reach in the medical device market.
Interpore Cross
Acquisition in 2004
Biomet designs, manufactures and markets surgical and non-surgical products used primarily by orthopedic surgeons.
Implex
Acquisition in 2004
Implex is a multifaceted company that operates in the fields of information technology and orthopedic medical devices. On one hand, it specializes in IT services, offering solutions such as website design, internet and server networks, online broadcasting, and managed services. On the other hand, Implex develops advanced orthopedic implant products, including hedrocel biomaterial, which features an open cell, tantalum metal structure that resembles human cancellous bone. This innovative approach aims to enhance the treatment options available to orthopedic surgeons addressing diseases and injuries of the musculoskeletal system.
Centerpulse
Acquisition in 2003
Centerpulse is a privately held medical technology group, serves the reconstructive orthopedic device, spinal device, and dental implant markets on a global basis.
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