Zimmer, Inc., operating as Zimmer Biomet, specializes in the design, manufacture, and marketing of orthopedic and dental products. The company offers a wide range of solutions, including joint replacement products for the knee, hip, and shoulder, as well as elbow and trauma devices, foot and ankle systems, and spinal solutions. Zimmer Biomet also provides dental implants and various surgical and operating room equipment, alongside biologics and sports medicine solutions. These products are aimed at helping healthcare professionals treat a variety of conditions, including arthritis and traumatic injuries, ultimately supporting patient mobility. Founded in 1927 and headquartered in Warsaw, Indiana, Zimmer Biomet operates multiple manufacturing facilities across the United States and internationally, including locations in Puerto Rico, Switzerland, and Ireland, and maintains a biologics research facility in Texas.
Paragon 28, Inc. is a medical device company focused on developing and distributing surgical solutions for foot and ankle procedures. Established in 2010 and headquartered in Englewood, Colorado, with an additional location in Dublin, Ireland, the company offers a diverse range of products, including forefoot, midfoot, and hindfoot plates, screws, allograft bone systems, and various staples and nails. Its offerings address critical orthopedic needs, such as arthrodesis, hallux valgus corrections, and fracture fixation, encompassing nearly 80 product systems tailored to meet the specific requirements of patients and surgical procedures. The majority of its revenue is generated in the United States, reflecting its strong presence in the orthopedic implant marketplace.
OrthoGrid provides intraoperative alignment navigation via procedure-specific musculoskeletal applications for THA, Hip Preservation, and Trauma. Its AI-enabled surgical guidance technology imports images from C-arm image intensifiers to reveal and correct fluoroscopic distortion and helps surgeons achieve desirable and reproducible surgical outcomes.
Osteal Therapeutics is a clinical-stage specialty pharmaceutical company focused on developing innovative drug and device combination products aimed at treating musculoskeletal infections. The company's therapeutics are designed to significantly reduce the mortality and morbidity associated with these infections, as well as the related healthcare costs. Osteal Therapeutics offers solutions for orthopedic infections, including those affecting infected joint prostheses, providing fast and reliable treatment options. This enables orthopedic surgeons to deliver effective care for musculoskeletal diseases, enhancing patient outcomes and addressing a critical need in the field of infection therapeutics.
OSSIS is a company focused on the development of orthopedic implants specifically designed for acetabular revisions and pelvic tumors. Utilizing advanced digital image manipulation, design software, and three-dimensional (3D) printing technology in titanium, OSSIS creates implants that provide effective anchor points for reattaching soft tissue. This innovative approach enhances the ability of medical professionals to treat their patients, improving surgical outcomes and patient care in the field of orthopedics.
Embody, Inc. is a regenerative medicine company based in Norfolk, Virginia, dedicated to developing and commercializing implantable medical devices aimed at soft tissue restoration and regeneration. Founded in 2014, the company specializes in biomaterial design and bio-fabrication, focusing on collagen-based microfibers for tendon and ligament repair. Its innovative products are designed to meet the needs of warfighters, athletes, and individuals with sports injuries, utilizing a precision medicine approach to replicate the biological and biomechanical properties of native tissue. The goal of Embody is to enhance the quality of life for patients by restoring their pre-injury performance through effective healing solutions.
ReLign Corporation is a developer and manufacturer of arthroscopes. The company's system includes a re-usable, sterilizable handle integrated with a single umbilical cable or conduit for cutting and removal of bone and soft tissue with an electrosurgical device, enabling orthopedic surgeons to visualize, diagnose and treat problems inside a joint painlessly and cost-effectively.
SIG Medical Corp. is a medical device manufacturing company based in Hershey, Pennsylvania, founded in 2016. The company specializes in developing a novel, minimally invasive surgical repair procedure for fractured ribs, offering a patented and FDA-approved rib fixation system. This system is designed to provide effective fixation, stabilization, and fusion of rib fractures and osteotomies in both normal and osteoporotic bone. By prioritizing a less costly, less time-consuming, and less painful approach, SIG Medical aims to enhance patient care while also reducing healthcare spending for payors. Their innovative devices are optimized for the operating room, allowing surgeons to perform rib repairs more efficiently and effectively.
RespondWell, LLC is a digital health company that specializes in a telerehabilitation platform designed for patients and healthcare providers, including outpatient rehabilitation clinics and senior care facilities. Founded in 2003 and based in Grand Rapids, Michigan, RespondWell offers a range of services that include prevention and rehabilitation modules, clinical content, and tools for clinicians. The platform facilitates patient engagement by allowing access to instructional videos for physical therapies, and incorporates features such as in-product rewards to enhance motivation. Additionally, it provides personalized rehabilitation programs and utilizes sensors to monitor patient performance. RespondWell, which was previously known as Respondesign, Inc., was acquired by Zimmer Biomet Holdings in October 2016.
Clinical Graphics B.V., founded in 2010 and based in Delft, the Netherlands, specializes in 3D motion simulation technology aimed at informing treatment decisions for orthopedic conditions, particularly those related to the hip. The company provides a service called Move Forward, which allows orthopedic surgeons and radiologists to submit image data, including CT and MRI scans, to receive detailed 3D motion simulation reports. These reports help physicians better understand the physiological aspects of a patient's pain, enabling them to tailor treatment approaches for conditions such as dysplasia and femoroacetabular impingement. Since September 2016, Clinical Graphics operates as a subsidiary of Zimmer Biomet Holdings, enhancing its capabilities in the medical imaging sector.
CD Diagnostics is developing assays for orthopaedic surgeons and rheumatologists who would like greater diagnostic confidence in joint fluid analysis. Unlike current technologies, which often yield vague and ambiguous results, CygnaSure™, our lead product, offers orthopaedic surgeons and rheumatologists a rapid, accurate and reliable diagnostic answer.
Medtech’s mission statement can be summarized in the following way: Their mission consists of the broader use of medical technology for the benefit of both patient and practitioner as they strive for improved overall health and well-being. Medtech designs, develops and markets a new generation of robotic assistance for the express purpose of improved surgical techniques. Their robots contribute to safer and more stable implementation of both more effective and less invasive treatment.
Compression Therapy Concepts, Inc. specializes in the production and distribution of medical products aimed at preventing deep vein thrombosis (DVT) and reducing the risk of pulmonary embolism. Established in 1999 and based in Eatontown, New Jersey, the company offers a range of products, including the VasoPress DVT system, various garment sizes for different patient needs, and necessary connector tubing. Its offerings are designed to enhance patient outcomes and minimize complications associated with DVT by integrating with care practices in acute, long-term, and home care settings. The company operates through a sales network across the United States and emphasizes cost-effective, environmentally friendly solutions in its product line.
LDR Holding Corporation is a medical device company that specializes in developing and marketing implantable spine systems and instrumentation for both patients and surgeons. The company offers a range of spinal surgery solutions, including artificial disc systems, pedicle screw systems, cervical cages, and various implant systems designed for cervical and lumbar applications. LDR Holding also provides synthetic bone substitutes and innovative surgical technologies, such as the VerteBRIDGE product, which is tailored for specific surgical procedures. Its products are distributed in numerous countries, including Australia, Japan, and various European nations, through partnerships with surgeons and distributors. Founded in 2004 and headquartered in Austin, Texas, LDR Holding has expanded its presence internationally with additional offices in France, China, Brazil, and Germany. The company was previously known as LDR Spine USA, Inc. before rebranding following its acquisition of LDR Médical.
Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.
Ortho Transmission
Acquisition in 2016
Ortho Transmission has develops a skeletal implant technology.
Etex Corporation develops, manufactures and commercializes calcium phosphate-based biomaterials for improved orthopedic clinical outcomes. A leader in bioresorbable bone substitute materials, ETEX focuses on expanding applications through combinations with cells, biologics, or therapeutic agents delivered in minimally invasive and easy to use systems.
Biomet, Inc., together with its subsidiaries, engages in the design, manufacture, and marketing of surgical and non-surgical products primarily used by orthopedic surgeons and other musculoskeletal medical specialists in the United States, Europe, and internationally. The company’s reconstructive products include knee, hip, shoulders, and extremity joint replacement systems, as well as dental reconstructive implants, bone cements, and accessories; autologous therapy products; and the procedure-specific instrumentation required to implant the company’s reconstructive systems. It also offers various fixation devices comprising internal and external fixation devices, craniomaxillofacial fixation systems, and electrical stimulation devices. In addition, the company supplies spinal products, which include electrical stimulation devices addressing the spine, spinal fixation systems, and orthobiologics for the spine. Further, it offers sports medicine products, softgoods and bracing products, casting materials, general surgical instruments, operating room supplies, and other surgical products. The company was founded in 1977 and is headquartered in Warsaw, Indiana. Biomet, Inc. is a subsidiary of LVB Acquisition, Inc.
Normed Medizin-Technik GmbH is a subsidiary of Zimmer Biomet Holdings Inc., focused on the development, manufacturing, and distribution of medical products globally. The company specializes in hand and foot surgery, offering a range of surgical products that include solutions for pediatric orthopedics and both lower and upper extremities. Normed prioritizes quality, service, and competence in its operations, aiming to enhance patient care through innovative medical solutions.
Knee Creations is an orthopedic medical device company that provides solutions to knee osteoarthritis. It pioneered the Subchondroplasty procedure, a minimally invasive solution designed to treat bone defects associated with chronic bone marrow lesions (BMLs) by filling them with a hard-setting, biomimetic bone void filler. The company was incorporated in 2007 and is based in New York, New York. As of May 2, 2013, Knee Creations, LLC operates as a subsidiary of Zimmer Holdings, Inc.
Dornoch Medical Systems is a manufacturer based in the United States that specializes in fluid management systems. The company produces an integrated infectious fluid collection and disposal system known as transposal, which is designed for use in operating rooms and across various healthcare facilities. In addition to its core products, Dornoch Medical Systems also offers a range of fluid management accessories to support healthcare operations.
Synvasive Technology, Inc. specializes in the development, manufacture, and distribution of advanced surgical cutting instruments for reconstructive orthopedic surgery. With nearly twenty years of experience, the company is recognized for its patented and proprietary technologies, including the STABLECUT® large bone surgical saw blades, which are considered the industry gold standard. By focusing on innovation and quality, Synvasive aims to enhance surgical outcomes and improve the efficiency of orthopedic procedures.
ExtraOrtho
Acquisition in 2011
ExtraOrtho, Inc. provides damage control and deformity correction solutions for surgeons, administrators, and patients. It offers XTRAFIX, an external fixation system that allows surgeons to eliminate steps, bars, and clamps. ExtraOrtho, Inc. was formerly known as QFx Technologies, Inc. and changed its name to ExtraOrtho, Inc. in May 2009. The company was founded in 2007 and is based in Memphis, Tennessee. As of November 10, 2011, ExtraOrtho, Inc. operates as a subsidiary of Zimmer Holdings, Inc.
Zfx provides dentists, dental labs and milling centres with high-end applications from the entire dental process chain: from the intraoral and desktop scanner and dental shade measuring instrument through to digital axiography and CAD software to the complete solution for dental milling providers. In addition, as Zfx partner you benefit from the new and unique Zfx online platform, which allows for continues control and replacement opportunities during the entire dental production process.
Zimmer Surgical
Acquisition in 2010
Sodem Diffusion S.A., the manufacturer of SoPlus Orthopaedic Surgical Power Tools based in Geneva, Switzerland. The company will be re-named Zimmer Surgical, S.A. and will be part of Zimmer Surgical, headquartered in Dover, Ohio.
Beijing Montagne Medical Device Co., Ltd.
Acquisition in 2010
Beijing Montagne Medical Device Co., Ltd. is a privately held company deals and engages in the development, production, and sale of artificial joints in China and abroad.
Abbott Spine, founded in 1996 and headquartered in Austin, Texas, with an international facility in Bordeaux, France, specializes in developing innovative spinal implant technologies aimed at treating spine diseases. The company focuses on creating less invasive solutions that enable surgeons to address various spinal disorders, diseases, and injuries effectively. Notable products include the InCompass Pedicle Screw System, the Pathfinder Minimally Invasive Pedicle Screw System, the Wallis Interspinous Stabilizer System (available outside the U.S.), the Ant-Cer Dynamic Cervical Plate, and the Universal Clamp. Through its advancements, Abbott Spine has established a reputation for improving surgical outcomes in spinal care.
Endius was founded in 1997 to provide less traumatic and more effective surgery for the of patients treated for back pain. The company develops invasive and endoscopic spine surgery products and implants and is committed to developing total spine surgery solutions. The company's products include the Atavi system, the TiTLE, and the MDS microdebrider system. Endius is acquired by Zimmer Biomet Holdings.
Implex is a multifaceted company that operates in the fields of information technology and orthopedic medical devices. On one hand, it specializes in IT services, offering solutions such as website design, internet and server networks, online broadcasting, and managed services. On the other hand, Implex develops advanced orthopedic implant products, including hedrocel biomaterial, which features an open cell, tantalum metal structure that resembles human cancellous bone. This innovative approach aims to enhance the treatment options available to orthopedic surgeons addressing diseases and injuries of the musculoskeletal system.
Centerpulse
Acquisition in 2003
Centerpulse is a privately held medical technology group, serves the reconstructive orthopedic device, spinal device, and dental implant markets on a global basis.
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