MB Venture Partners, established in 2001, is a Tennessee-based venture capital firm headquartered in Memphis. The company specializes in providing equity capital and strategic guidance to life sciences businesses, with a focus on medical device and biotechnology companies at various stages of development. MB Venture Partners is particularly interested in product solutions for musculoskeletal diseases, leveraging its partners' extensive experience and relationships in this field. The firm invests across the Southeast and Midwest regions of the United States.
Lineus Medical specializes in medical devices aimed at enhancing vascular access and preventing complications associated with intravenous (IV) therapy. The company's flagship product, the SafeBreak Vascular device, employs patented break-away technology that allows for a controlled separation in the IV tubing when excessive tension is applied. This innovation helps prevent dislodgement of access lines, reducing the risks of blood loss and infection, and ultimately improving the overall quality of care for patients undergoing IV treatment. By focusing on the safety and effectiveness of IV therapy, Lineus Medical addresses a critical aspect of patient care in healthcare settings.
SweetBio
Seed Round in 2018
SweetBio, Inc. is a medical device company based in Memphis, Tennessee, specializing in the research, development, and manufacturing of innovative wound care solutions. Founded in 2015, the company focuses on bioengineering membranes that utilize medical-grade Manuka honey to enhance healing and combat infections associated with wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. SweetBio's unique honey-incorporated absorbable membranes are designed to improve the efficacy of wound care treatments, offering healthcare professionals a new platform for addressing both chronic and acute wounds effectively.
Cast21
Seed Round in 2017
Cast21 is a medical product developer based in Memphis, Tennessee, focused on creating innovative orthopedic solutions for fracture and joint care. Established in 2015, the company has developed a waterproof and breathable cast designed to enhance patient comfort and facilitate recovery. Its unique design not only allows for skin hygiene—enabling patients to wash and scratch beneath the cast—but also supports the integration of electronic therapies aimed at reducing healing time. By prioritizing user experience and effective treatment, Cast21 seeks to improve the overall recovery process for individuals with orthopedic injuries.
Spine Wave
Series F in 2016
Spine Wave, Inc. is a manufacturer of medical devices focused on the treatment of spinal disorders. Founded in 2001 and based in Shelton, Connecticut, the company develops and markets a range of innovative products aimed at providing surgical solutions for spine surgeons and their patients. Its offerings include expandable PEEK spacers, interbody devices for posterior surgery, pivoting and lateral spacer systems, and the GraftMag Graft Delivery System for bone graft delivery. Additionally, Spine Wave produces fixation products designed for addressing degeneration, deformity, tumors, and trauma in the thoracolumbar spine, as well as anterior cervical plate systems for spinal fusion from C2-C7 and cervical spacer systems for degenerative disc disease from C2-T1. The company distributes its products through a network of distributors, emphasizing a surgeon-driven approach to product development to address real surgical challenges.
Lineus Medical
Seed Round in 2016
Lineus Medical specializes in medical devices aimed at enhancing vascular access and preventing complications associated with intravenous (IV) therapy. The company's flagship product, the SafeBreak Vascular device, employs patented break-away technology that allows for a controlled separation in the IV tubing when excessive tension is applied. This innovation helps prevent dislodgement of access lines, reducing the risks of blood loss and infection, and ultimately improving the overall quality of care for patients undergoing IV treatment. By focusing on the safety and effectiveness of IV therapy, Lineus Medical addresses a critical aspect of patient care in healthcare settings.
SweetBio
Pre Seed Round in 2015
SweetBio, Inc. is a medical device company based in Memphis, Tennessee, specializing in the research, development, and manufacturing of innovative wound care solutions. Founded in 2015, the company focuses on bioengineering membranes that utilize medical-grade Manuka honey to enhance healing and combat infections associated with wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. SweetBio's unique honey-incorporated absorbable membranes are designed to improve the efficacy of wound care treatments, offering healthcare professionals a new platform for addressing both chronic and acute wounds effectively.
Ortho Kinematics
Venture Round in 2015
Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.
Restore Medical Solutions
Series A in 2015
Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.
Ortho Kinematics
Series C in 2015
Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.
Better Walk
Series A in 2015
Better Walk Inc. is an innovative company that specializes in the design and development of crutches. Established in 2013 and headquartered in Atlanta, Georgia, the company aims to improve traditional crutch technology by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. Better Walk's commitment to innovation is a fundamental aspect of its culture, which was further strengthened during its participation in the Zero To 510 accelerator in Memphis, where it secured early venture funding. In late 2014, the company shifted its focus to finalizing the Better Walk crutch, positioning itself for production and an anticipated product launch in early 2015.
EndoInSight
Seed Round in 2014
EndoInSight specializes in developing a disposable insufflation system aimed at alleviating the pain and discomfort associated with colonoscopy procedures used for colorectal cancer screening. The company utilizes carbon dioxide for colon inflation, a method that significantly reduces post-procedural discomfort compared to traditional air insufflation. Despite the known advantages of using CO2, its adoption in clinical settings has been limited due to low awareness and the high costs of existing insufflation systems. By offering a cost-effective solution, EndoInSight seeks to enhance patient comfort and improve overall outcomes in colorectal cancer treatment.
CrossRoads Extremity Systems
Venture Round in 2014
CrossRoads Extremity Systems, LLC is a medical device manufacturing company based in Memphis, Tennessee, specializing in implant systems for foot and ankle surgery. Founded in 2014, the company designs, manufactures, and markets a variety of surgical implants, including the MotoBAND CP Plating System for midfoot and forefoot procedures, the STRoPP implant kit, and the MotoCLIP which provides elastic fixation for healing bones. Additionally, CrossRoads produces the CrossTIE PIP Implant for hammertoe correction, various CrossTIE implant configurations for revision cases, and EcoSMART, an instrument recovery service. The company also develops Allograft wedges for consistent surgical handling, DBM putties, and advanced systems like DynaFORCE and Keel-Lock for enhanced surgical outcomes. CrossRoads Extremity Systems distributes its products through various partners in the United States, aimed at improving the operating room experience and achieving better patient outcomes.
Zyga Technology
Series D in 2014
Zyga Technology, Inc. is a medical device company focused on developing and commercializing minimally invasive products for underserved conditions of the lumbar spine. The company offers the SImmetry Sacroiliac Joint Fusion System, which provides a surgical solution for sacroiliac joint fusion, addressing issues such as joint disruptions and degenerative sacroiliitis. Additionally, Zyga is working on the Glyder Facet Restoration System, an investigational device aimed at treating chronic facetogenic pain. Founded in 2008 and based in Minnetonka, Minnesota, Zyga Technology has assembled a skilled team with extensive experience in the spine industry. As of late 2017, Zyga operates as a subsidiary of RTI Surgical, Inc.
EcoSurg
Seed Round in 2014
EcoSurg is a developer of environmentally-friendly surgical supplies aimed at minimizing the carbon footprint in surgical settings. The company’s primary product, the EcoSurg line of patient positioners, consists of disposable foam shapes designed for use in over 20 million surgical procedures annually in the United States. These positioners help ensure patient safety, comfort, and proper access to surgical sites. Traditional disposable positioners are made from petroleum-based materials, which pose environmental hazards and lead to increased disposal costs. EcoSurg's innovative approach seeks to address these concerns by providing sustainable alternatives that reduce environmental impact while maintaining the necessary functionality for surgical procedures.
Blood Monitoring Solutions
Seed Round in 2014
Blood Monitoring Solutions, Inc. is dedicated to developing innovative blood monitoring systems aimed at reducing blood wastage. Based in Memphis, Tennessee, the company has created a smart blood transport system that enables blood banks to continuously monitor the temperature and integrity of each blood unit. This proactive, data-driven approach not only enhances patient safety but also helps hospitals minimize costs associated with blood spoilage. By ensuring that blood is stored within the appropriate temperature range, the company's solutions allow for longer preservation of blood supplies, ultimately supporting more effective transfusion practices in healthcare settings.
Compression Kinetics
Seed Round in 2014
Compression Kinetics, Inc. is a Memphis-based company specializing in the design and development of innovative medical devices, particularly dynamic compression sleeves. These sleeves utilize shape memory alloy technology to generate pressure waves that enhance circulation, reduce peripheral edema, and help prevent blood clots. By translating clinically proven compression therapy into a sleek and mobile format, Compression Kinetics is positioned to make a significant impact in the $11 billion athletic compression apparel market. The company's products aim to improve recovery times and athletic performance for users, making advanced compression therapy accessible to both amateur and professional athletes.
Innometrix
Seed Round in 2014
Innometrix, Inc. is a Memphis-based company focused on developing advanced technology to enhance the diagnosis and treatment of female pelvic floor disorders. These conditions are prevalent, affecting approximately 50% of women who have given birth, and they contribute to significant healthcare costs. Innometrix aims to translate biomechanics into clinical solutions by producing a biomechanical snapshot of the female pelvic floor, providing physicians with vital data prior to surgical procedures. The company addresses the limitations of current treatment methods, which often rely on subjective judgment and have high complication rates. By creating innovative device solutions, Innometrix seeks to improve treatment outcomes and increase patient satisfaction in a field that requires significant advancements.
CamPlex
Seed Round in 2014
CamPlex is a U.S.-based company founded in 2012 and headquartered in Germantown, Tennessee, specializing in the healthcare industry. The company focuses on manufacturing high-quality fiber optic products designed to enhance performance and extend signal transmission capabilities. CamPlex offers innovative fiber optic-based camera adapter systems and broadcast-grade interface gear, which help broadcast professionals streamline signal delivery and improve operational efficiency. By providing these solutions, CamPlex aims to reduce operating costs and eliminate the necessity for additional components and costly replacements.
Tidal Wave Technology
Seed Round in 2014
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.
Hubble Telemedical
Series A in 2014
Hubble Telemedical focuses on the early detection of systemic and debilitating diseases that can be identified through retinal examination. Their Telemedical Retinal Image Analysis and Diagnosis (TRIAD) technology offers real-time diagnosis of diabetic retinopathy and other retinal conditions, utilizing commonly available retina cameras. This innovative approach addresses the issue of many at-risk individuals not receiving necessary annual retinal exams due to accessibility and convenience challenges. By partnering with healthcare providers, insurance companies, and employers, Hubble Telemedical aims to make retinal screening more accessible, ultimately improving health outcomes and reducing healthcare costs. Their services are fully compliant with HIPAA regulations, ensuring security and ease of use. Clinical studies support the effectiveness of their technology in increasing annual screening compliance, thereby enhancing patient care and facilitating timely treatment for various diseases.
Restore Medical Solutions
Series A in 2014
Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.
Mobilizer
Seed Round in 2014
Mobilizer Inc. is a company that specializes in the development of innovative six-wheeled holsters designed for medical equipment, aimed at enhancing the efficiency of patient ambulation in healthcare settings. Modeled after a wheeled walker, these holsters feature shelves and attachments that facilitate the transportation of equipment necessary for the mobility of critical care patients. By improving the process of medical ambulation, Mobilizer aims to enhance patient well-being while streamlining operations within hospitals. The company is a graduate of the ZeroTo510 medical device startup accelerator, further validating its commitment to advancing healthcare solutions.
Hapten Sciences
Venture Round in 2014
Hapten Sciences, Inc. is a privately-held biopharmaceutical company based in Memphis, Tennessee, established in 2010. The company focuses on the identification and development of early-stage products aimed at improving global health outcomes. One of its key innovations is PDC-APB, a vaccine designed to prevent contact dermatitis resulting from exposure to urushiol oil found in poison ivy, poison oak, and poison sumac. This product aims to provide patients with a solution to avoid allergic reactions without side effects, thereby contributing significantly to the well-being of individuals affected by these plants.
iScreen Vision
Series B in 2013
iScreen Vision, Inc. is a medical device company based in Cordova, Tennessee, specializing in pediatric vision screening solutions. Founded in 2009, the company utilizes advanced photoscreening technology to provide a fast and portable method for detecting vision problems in infants, preschool, and school-age children. By offering physicians a patented digital photoscreening device, iScreen Vision enables efficient screening for common childhood vision issues, including those that may lead to amblyopia if not addressed promptly. The company also integrates cloud-based transmission, analysis, and storage of screening images, facilitating seamless coordination with Electronic Medical Records (EMR) systems for healthcare providers.
Focal Point Pharmaceuticals
Seed Round in 2013
Focal Point Pharmaceuticals is a healthcare company focused on pharmaceutical businesses. It was incorporated in 2013 and is based in Memphis, Tennessee, United States.
BioNanovations
Seed Round in 2013
BioNanovations is a medical technology company focused on the rapid diagnosis of bacterial infections, particularly Staphylococcus infections. Currently, diagnosing these infections takes 3 to 5 days, which can be critical due to the aggressive nature of certain strains that may lead to severe health consequences, including limb amputation or death within 48 hours. To address these challenges, BioNanovations is developing a handheld diagnostic platform that significantly reduces the testing time to under 30 minutes. This integrated real-time diagnostic solution enables healthcare professionals to quickly analyze blood, sputum, urine, and cerebrospinal fluid, facilitating immediate access to vital diagnostic information. By providing real-time data on bacterial infections, the platform not only improves patient outcomes by reducing morbidity and mortality rates but also supports healthcare professionals and agencies in tracking epidemiological trends effectively.
Better Walk
Seed Round in 2013
Better Walk Inc. is an innovative company that specializes in the design and development of crutches. Established in 2013 and headquartered in Atlanta, Georgia, the company aims to improve traditional crutch technology by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. Better Walk's commitment to innovation is a fundamental aspect of its culture, which was further strengthened during its participation in the Zero To 510 accelerator in Memphis, where it secured early venture funding. In late 2014, the company shifted its focus to finalizing the Better Walk crutch, positioning itself for production and an anticipated product launch in early 2015.
iScreen Vision
Series B in 2013
iScreen Vision, Inc. is a medical device company based in Cordova, Tennessee, specializing in pediatric vision screening solutions. Founded in 2009, the company utilizes advanced photoscreening technology to provide a fast and portable method for detecting vision problems in infants, preschool, and school-age children. By offering physicians a patented digital photoscreening device, iScreen Vision enables efficient screening for common childhood vision issues, including those that may lead to amblyopia if not addressed promptly. The company also integrates cloud-based transmission, analysis, and storage of screening images, facilitating seamless coordination with Electronic Medical Records (EMR) systems for healthcare providers.
Mobilizer
Seed Round in 2013
Mobilizer Inc. is a company that specializes in the development of innovative six-wheeled holsters designed for medical equipment, aimed at enhancing the efficiency of patient ambulation in healthcare settings. Modeled after a wheeled walker, these holsters feature shelves and attachments that facilitate the transportation of equipment necessary for the mobility of critical care patients. By improving the process of medical ambulation, Mobilizer aims to enhance patient well-being while streamlining operations within hospitals. The company is a graduate of the ZeroTo510 medical device startup accelerator, further validating its commitment to advancing healthcare solutions.
EcoSurg
Seed Round in 2013
EcoSurg is a developer of environmentally-friendly surgical supplies aimed at minimizing the carbon footprint in surgical settings. The company’s primary product, the EcoSurg line of patient positioners, consists of disposable foam shapes designed for use in over 20 million surgical procedures annually in the United States. These positioners help ensure patient safety, comfort, and proper access to surgical sites. Traditional disposable positioners are made from petroleum-based materials, which pose environmental hazards and lead to increased disposal costs. EcoSurg's innovative approach seeks to address these concerns by providing sustainable alternatives that reduce environmental impact while maintaining the necessary functionality for surgical procedures.
Ortho Kinematics
Series B in 2013
Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.
Hapten Sciences
Seed Round in 2013
Hapten Sciences, Inc. is a privately-held biopharmaceutical company based in Memphis, Tennessee, established in 2010. The company focuses on the identification and development of early-stage products aimed at improving global health outcomes. One of its key innovations is PDC-APB, a vaccine designed to prevent contact dermatitis resulting from exposure to urushiol oil found in poison ivy, poison oak, and poison sumac. This product aims to provide patients with a solution to avoid allergic reactions without side effects, thereby contributing significantly to the well-being of individuals affected by these plants.
Hubble Telemedical
Seed Round in 2013
Hubble Telemedical focuses on the early detection of systemic and debilitating diseases that can be identified through retinal examination. Their Telemedical Retinal Image Analysis and Diagnosis (TRIAD) technology offers real-time diagnosis of diabetic retinopathy and other retinal conditions, utilizing commonly available retina cameras. This innovative approach addresses the issue of many at-risk individuals not receiving necessary annual retinal exams due to accessibility and convenience challenges. By partnering with healthcare providers, insurance companies, and employers, Hubble Telemedical aims to make retinal screening more accessible, ultimately improving health outcomes and reducing healthcare costs. Their services are fully compliant with HIPAA regulations, ensuring security and ease of use. Clinical studies support the effectiveness of their technology in increasing annual screening compliance, thereby enhancing patient care and facilitating timely treatment for various diseases.
Cuff-Protect
Seed Round in 2013
Cuff-Mate skin barriers offer healthcare professionals a cost-effective way to protect their patients, themselves and equipment when taking vital signs.
AIS
Seed Round in 2013
Although it is still relatively new, AIS, having a relationship with other biology-inspired computing models, and computational biology.
Health & Bliss
Seed Round in 2013
Health & Bliss Inc. is a medical device company based in Memphis, Tennessee, specializing in the design, patenting, and sale of medical products and diagnostic tests. The company has developed Strep Test Anywhere, an innovative point-of-care device that enables testing for multiple infections, including strep throat, influenza A/B, chlamydia, gonorrhea, hepatitis B/C, and several other illnesses. By providing a means to obtain accurate test results without the need for a doctor visit, Health & Bliss aims to address significant barriers to effective healthcare, specifically time and cost. Their technology is designed to improve patient access to diagnostic services while benefiting healthcare providers and payers alike.
SurgiLight
Seed Round in 2013
SurgiLight offers a surgical lighting system that provides surgeons with a practical illumination device, enabling them to focus on target areas.
Better Walk
Seed Round in 2013
Better Walk Inc. is an innovative company that specializes in the design and development of crutches. Established in 2013 and headquartered in Atlanta, Georgia, the company aims to improve traditional crutch technology by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. Better Walk's commitment to innovation is a fundamental aspect of its culture, which was further strengthened during its participation in the Zero To 510 accelerator in Memphis, where it secured early venture funding. In late 2014, the company shifted its focus to finalizing the Better Walk crutch, positioning itself for production and an anticipated product launch in early 2015.
Mobilizer
Seed Round in 2013
Mobilizer Inc. is a company that specializes in the development of innovative six-wheeled holsters designed for medical equipment, aimed at enhancing the efficiency of patient ambulation in healthcare settings. Modeled after a wheeled walker, these holsters feature shelves and attachments that facilitate the transportation of equipment necessary for the mobility of critical care patients. By improving the process of medical ambulation, Mobilizer aims to enhance patient well-being while streamlining operations within hospitals. The company is a graduate of the ZeroTo510 medical device startup accelerator, further validating its commitment to advancing healthcare solutions.
Spinal Restoration
Series C in 2013
Spinal Restoration, Inc. is a company focused on developing early intervention and minimally invasive therapies for chronic low back pain. Established in 2004 and headquartered in New York, it has created the Biostat System, which is designed to address chronic discogenic pain caused by internal disc disruptions. This system includes a resorbable biologic compound known as BIOSTAT BIOLOGX Fibrin Sealant, which acts as a tissue sealant, and a proprietary delivery device that administers the biologic directly to the intervertebral disc. The Biostat System aims to provide an effective treatment option for the significant population of adults—approximately four million—suffering from chronic low back pain.
Tidal Wave Technology
Seed Round in 2013
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.
AxioMed
Series D in 2013
AxioMed LLC specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. Founded in 2001 and based in Malden, Massachusetts, the company was previously known as AxioMed Spine Corporation until its name change in 2014. AxioMed has developed the Freedom® Lumbar Disc and initiated clinical trials for its products, which are intended to improve the standard of care beyond traditional fusion and first-generation artificial discs. The company is led by CEO Patrick McBrayer and COO James Kuras, who oversee a team with extensive experience in spinal implants and engineering. They are supported by a Medical Advisory Panel of surgeons from prominent spine centers and universities. AxioMed's operations encompass product development, testing, clinical and regulatory affairs, and manufacturing, with ongoing projects focusing on cervical spine solutions.
Restore Medical Solutions
Series A in 2012
Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.
Hubble Telemedical
Seed Round in 2012
Hubble Telemedical focuses on the early detection of systemic and debilitating diseases that can be identified through retinal examination. Their Telemedical Retinal Image Analysis and Diagnosis (TRIAD) technology offers real-time diagnosis of diabetic retinopathy and other retinal conditions, utilizing commonly available retina cameras. This innovative approach addresses the issue of many at-risk individuals not receiving necessary annual retinal exams due to accessibility and convenience challenges. By partnering with healthcare providers, insurance companies, and employers, Hubble Telemedical aims to make retinal screening more accessible, ultimately improving health outcomes and reducing healthcare costs. Their services are fully compliant with HIPAA regulations, ensuring security and ease of use. Clinical studies support the effectiveness of their technology in increasing annual screening compliance, thereby enhancing patient care and facilitating timely treatment for various diseases.
Spinal Restoration
Venture Round in 2012
Spinal Restoration, Inc. is a company focused on developing early intervention and minimally invasive therapies for chronic low back pain. Established in 2004 and headquartered in New York, it has created the Biostat System, which is designed to address chronic discogenic pain caused by internal disc disruptions. This system includes a resorbable biologic compound known as BIOSTAT BIOLOGX Fibrin Sealant, which acts as a tissue sealant, and a proprietary delivery device that administers the biologic directly to the intervertebral disc. The Biostat System aims to provide an effective treatment option for the significant population of adults—approximately four million—suffering from chronic low back pain.
EcoSurg
Seed Round in 2012
EcoSurg is a developer of environmentally-friendly surgical supplies aimed at minimizing the carbon footprint in surgical settings. The company’s primary product, the EcoSurg line of patient positioners, consists of disposable foam shapes designed for use in over 20 million surgical procedures annually in the United States. These positioners help ensure patient safety, comfort, and proper access to surgical sites. Traditional disposable positioners are made from petroleum-based materials, which pose environmental hazards and lead to increased disposal costs. EcoSurg's innovative approach seeks to address these concerns by providing sustainable alternatives that reduce environmental impact while maintaining the necessary functionality for surgical procedures.
Tidal Wave Technology
Seed Round in 2012
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.
Urova Medical
Seed Round in 2012
Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on creating innovative solutions for stress urinary incontinence in women. Founded in 2012, the company developed its technology through a collaborative effort by biomedical engineering students at Johns Hopkins University, guided by expert physicians from the institution's renowned urological center. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and convenient treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which is supported by local venture capital firms, further enhancing its development and outreach efforts.
Nanophthalmics
Seed Round in 2012
Nanophthalmics is a developer of innovative surgical devices and techniques aimed at enhancing treatment outcomes for ophthalmic and microsurgical diseases. The company has created a patent-pending platform technology for microfabricated instruments that engage tissue in novel ways. Their flagship product is a disposable corneal micro-punch, which is designed to improve healing in cases of abrasions, recurrent erosions, and other corneal diseases by altering tissue attachments at the cellular level. By focusing on advanced surgical devices and methods, Nanophthalmics seeks to transform the landscape of ophthalmic treatment and offer better solutions for healthcare providers.
BioNanovations
Seed Round in 2012
BioNanovations is a medical technology company focused on the rapid diagnosis of bacterial infections, particularly Staphylococcus infections. Currently, diagnosing these infections takes 3 to 5 days, which can be critical due to the aggressive nature of certain strains that may lead to severe health consequences, including limb amputation or death within 48 hours. To address these challenges, BioNanovations is developing a handheld diagnostic platform that significantly reduces the testing time to under 30 minutes. This integrated real-time diagnostic solution enables healthcare professionals to quickly analyze blood, sputum, urine, and cerebrospinal fluid, facilitating immediate access to vital diagnostic information. By providing real-time data on bacterial infections, the platform not only improves patient outcomes by reducing morbidity and mortality rates but also supports healthcare professionals and agencies in tracking epidemiological trends effectively.
Restore Medical Solutions
Seed Round in 2012
Restore Medical Solutions, Inc. is a medical device company based in Memphis, Tennessee, founded in 2012. The company specializes in manufacturing modular sterilization tray systems designed for use in hospitals and surgery centers. These systems aim to reduce the risk of surgical site infections by minimizing contamination from medical instruments. By enhancing efficiency and safety in healthcare settings, Restore Medical Solutions helps surgical departments improve the quality of care while also lowering costs. The innovative design of its products contributes to better operational productivity and supports the overall goal of delivering high-standard healthcare.
HandMinder
Seed Round in 2012
HandMinder is a developer of a portable hand rehabilitation device designed to aid stroke survivors in regaining hand function. With approximately 7 million stroke survivors in the United States and 795,000 new or recurrent cases each year, many face significant hand dysfunction, which affects their quality of life. Current rehabilitation methods primarily focus on muscle rehabilitation, often leaving patients in a passive role, and can be both expensive and inconvenient. Recognizing the need for more effective solutions, HandMinder utilizes patent-pending vibration-guided brain engagement technology that enhances neural connections between the hand and brain. Research indicates that this active engagement can double the amount of hand movement and improve its quality by 2.5 times compared to traditional treatments. The HandMinder device is designed to be affordable and convenient, making it suitable for use in both clinical settings and at home, ultimately aiming to improve rehabilitation outcomes for stroke victims.
S2 Interactive
Seed Round in 2012
S2 Interactive, Inc. is a Delaware C corp. founded by Larry Foster, R.N., in September, 2011. After working as a surgical nurse and spending 26 years in leadership roles within sales, marketing and professional education in the orthopedic & spine industry, Larry was convinced there was an opportunity to teach hospital staff to learn and manage surgical instruments more efficiently and safely. Larry spent five years working with technology experts realizing with the current trends in healthcare there was a clear need to increase hospital staff productivity/efficiency while driving cost savings. Larry’s vision combined with the introduction of user-friendly “hand held” technology platforms (tablets) enabled S2 Interactive to develop Virtual Back Table and Tray Touch software platforms. In September, 2011 additional funding was provided by 2 Memphis based venture capital organizations, Innova & MB Ventures. They are proud to be working with market leading companies in Medical Devices and many of the nation’s most prominent hospitals. Their technology has been used by over 1,000 different users in a variety of surgical specialties including cardiology, orthopedics, spine , general surgery and trauma.
Hapten Sciences
Seed Round in 2012
Hapten Sciences, Inc. is a privately-held biopharmaceutical company based in Memphis, Tennessee, established in 2010. The company focuses on the identification and development of early-stage products aimed at improving global health outcomes. One of its key innovations is PDC-APB, a vaccine designed to prevent contact dermatitis resulting from exposure to urushiol oil found in poison ivy, poison oak, and poison sumac. This product aims to provide patients with a solution to avoid allergic reactions without side effects, thereby contributing significantly to the well-being of individuals affected by these plants.
Hubble Telemedical
Seed Round in 2012
Hubble Telemedical focuses on the early detection of systemic and debilitating diseases that can be identified through retinal examination. Their Telemedical Retinal Image Analysis and Diagnosis (TRIAD) technology offers real-time diagnosis of diabetic retinopathy and other retinal conditions, utilizing commonly available retina cameras. This innovative approach addresses the issue of many at-risk individuals not receiving necessary annual retinal exams due to accessibility and convenience challenges. By partnering with healthcare providers, insurance companies, and employers, Hubble Telemedical aims to make retinal screening more accessible, ultimately improving health outcomes and reducing healthcare costs. Their services are fully compliant with HIPAA regulations, ensuring security and ease of use. Clinical studies support the effectiveness of their technology in increasing annual screening compliance, thereby enhancing patient care and facilitating timely treatment for various diseases.
Urova Medical
Seed Round in 2012
Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on creating innovative solutions for stress urinary incontinence in women. Founded in 2012, the company developed its technology through a collaborative effort by biomedical engineering students at Johns Hopkins University, guided by expert physicians from the institution's renowned urological center. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and convenient treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which is supported by local venture capital firms, further enhancing its development and outreach efforts.
EcoSurg
Seed Round in 2012
EcoSurg is a developer of environmentally-friendly surgical supplies aimed at minimizing the carbon footprint in surgical settings. The company’s primary product, the EcoSurg line of patient positioners, consists of disposable foam shapes designed for use in over 20 million surgical procedures annually in the United States. These positioners help ensure patient safety, comfort, and proper access to surgical sites. Traditional disposable positioners are made from petroleum-based materials, which pose environmental hazards and lead to increased disposal costs. EcoSurg's innovative approach seeks to address these concerns by providing sustainable alternatives that reduce environmental impact while maintaining the necessary functionality for surgical procedures.
Zyga Technology
Series C in 2012
Zyga Technology, Inc. is a medical device company focused on developing and commercializing minimally invasive products for underserved conditions of the lumbar spine. The company offers the SImmetry Sacroiliac Joint Fusion System, which provides a surgical solution for sacroiliac joint fusion, addressing issues such as joint disruptions and degenerative sacroiliitis. Additionally, Zyga is working on the Glyder Facet Restoration System, an investigational device aimed at treating chronic facetogenic pain. Founded in 2008 and based in Minnetonka, Minnesota, Zyga Technology has assembled a skilled team with extensive experience in the spine industry. As of late 2017, Zyga operates as a subsidiary of RTI Surgical, Inc.
Tidal Wave Technology
Seed Round in 2012
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.
Veracity Medical
Seed Round in 2012
Veracity Medical Solutions, established in 2007 and headquartered in Collierville, Tennessee, is a medical device manufacturing company. It operates as a subsidiary of Arcamed, LLC. Veracity specializes in contract manufacturing, offering a comprehensive range of services from raw material to finished, packaged products. These include design, development, prototyping, custom, and special manufacturing services, ensuring clients can efficiently and accurately produce medical devices, surgical instrumentation, and implants.
Cayenne Medical
Venture Round in 2012
Cayenne Medical, Inc. is a medical device company specializing in soft tissue reconstruction solutions for the knee, shoulder, and extremities. Founded in 2005 and based in Scottsdale, Arizona, the company designs and markets a range of products aimed at improving surgical outcomes in sports medicine. Its offerings include the AperFix System, which facilitates anterior cruciate ligament (ACL) reconstruction using soft tissue grafts, as well as the AperFix II Cannulated Tibial Device and the AperFix Femoral Implant for anatomical soft tissue fixation. Cayenne Medical also provides the CrossFix II System for meniscal repair, the iFix for bone-tendon fixation, and the Cayenne Mirror Partial Knee System for early-stage knee arthritis treatment. In the shoulder category, the Quattro System addresses rotator cuff and labral repairs. Cayenne Medical operates as a subsidiary of Zimmer Biomet Holdings, enhancing its capacity to deliver innovative medical solutions.
MB Innovations
Seed Round in 2011
MB Innovations, Inc. is a medical technology development company based in Memphis, Tennessee, founded in 2011. The company specializes in providing research, design, and development services for established firms, particularly in the musculoskeletal industry, on a fee-for-service basis. Its offerings encompass the entire development process, from initial concept to first-in-man surgical procedures, allowing clients to enhance their products and secure market presence. Additionally, MB Innovations aims to develop its own technologies and intellectual property, fostering new ventures and job creation in the region. The company's strategic location in Memphis offers access to significant research and development capabilities, supported by a team of experienced engineers and surgeon advisors, which facilitates a focused approach to product development and accelerates time to market.
Ortho Kinematics
Series A in 2011
Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.
Ortho Kinematics
Series A in 2010
Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.
AxioMed
Series D in 2010
AxioMed LLC specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. Founded in 2001 and based in Malden, Massachusetts, the company was previously known as AxioMed Spine Corporation until its name change in 2014. AxioMed has developed the Freedom® Lumbar Disc and initiated clinical trials for its products, which are intended to improve the standard of care beyond traditional fusion and first-generation artificial discs. The company is led by CEO Patrick McBrayer and COO James Kuras, who oversee a team with extensive experience in spinal implants and engineering. They are supported by a Medical Advisory Panel of surgeons from prominent spine centers and universities. AxioMed's operations encompass product development, testing, clinical and regulatory affairs, and manufacturing, with ongoing projects focusing on cervical spine solutions.
Anulex Technologies
Series E in 2010
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
Calosyn Pharma
Seed Round in 2009
CaloSyn Pharma, Inc. is a biopharmaceutical company focused on developing intra-articular therapeutics specifically for osteoarthritis (OA), a condition affecting over 27 million people in the United States and more than 100 million globally. Founded in 2007 and headquartered in Boston, Massachusetts, with additional offices in Shreveport, Louisiana, and Atlanta, Georgia, the company is advancing a novel approach to OA treatment through the use of calcium channel blockers, drugs traditionally employed in heart and vascular disease management. By leveraging new insights into the mechanisms of these drugs and the processes underlying joint damage and pain in osteoarthritis, CaloSyn Pharma aims to reformulate and repurpose these medications for direct injection into affected joints. The company is currently conducting a Phase II clinical trial in the United States to evaluate the efficacy of its therapeutic approach.
Anulex Technologies
Series D in 2009
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
Visioneering Technologies
Venture Round in 2009
Visioneering Technologies, Inc., established in 2008 and based in Alpharetta, Georgia, is a medical device company specializing in the design, manufacture, and distribution of contact lenses. The company's flagship product, NaturalVue, is a multifocal contact lens designed to address presbyopia in adults and myopia in children. Visioneering operates in the United States, Australia, New Zealand, Europe, Hong Kong, and Singapore, offering innovative optical solutions that enhance practitioner and patient experiences. The company's portfolio is backed by fourteen issued patents worldwide, reflecting its commitment to creative and differentiated design approaches. Visioneering's leadership team comprises industry veterans from clinical, marketing, engineering, manufacturing, and regulatory backgrounds, ensuring the best thinking in eye care is applied to develop and bring to market new solutions for presbyopia, myopia, and astigmatism.
BrainsGate
Series C in 2008
BrainsGate, Ltd. is a medical device company based in Caesarea, Israel, specializing in therapies for patients with central nervous system diseases. The company has developed a technology platform that utilizes electrical stimulation of the spheno-palatine ganglion (SPG) to enhance cerebral blood flow. Currently, BrainsGate is focused on treating acute ischemic stroke through its innovative ischemic stroke system, which involves a miniature electrode implanted in the roof of the mouth during a minimally invasive procedure. This method is performed under local anesthesia and is comparable to standard dental treatments. The company has conducted several clinical trials, including a pivotal trial with 300 patients that validated the safety and efficacy of its treatment. BrainsGate is also engaged in a multi-national, randomized study known as ImpACT-24b, aimed at further assessing the effectiveness of its approach within a critical 24-hour window following a stroke.
Protein Discovery
Series C in 2008
Protein Discovery, Inc. is a life sciences company specializing in the development and commercialization of innovative sample preparation technologies for protein and peptide analysis via mass spectrometry. The company offers several key products, including the Gelfree 8100 fractionation system, which separates complex protein mixtures into liquid-phase molecular weight fractions, and the Passport 1200 sample preparation system, designed to enrich low molecular weight proteins and peptides while eliminating matrix interferences, facilitating high-throughput quantification. Additionally, Protein Discovery provides the PPS Silent Surfactant, a reagent that solubilizes membrane proteins and reduces detergent interference. The UPX universal protein extraction kit is also available for detergent extraction of proteins from cells and tissues. Catering to life science researchers and drug development scientists, Protein Discovery markets its products both through Agilent Technologies and online, reaching a global audience. Founded in 2001 in Knoxville, Tennessee, the company was originally named Qgenics Biosciences, Inc. before rebranding to its current name in 2004.
Cayenne Medical
Series C in 2008
Cayenne Medical, Inc. is a medical device company specializing in soft tissue reconstruction solutions for the knee, shoulder, and extremities. Founded in 2005 and based in Scottsdale, Arizona, the company designs and markets a range of products aimed at improving surgical outcomes in sports medicine. Its offerings include the AperFix System, which facilitates anterior cruciate ligament (ACL) reconstruction using soft tissue grafts, as well as the AperFix II Cannulated Tibial Device and the AperFix Femoral Implant for anatomical soft tissue fixation. Cayenne Medical also provides the CrossFix II System for meniscal repair, the iFix for bone-tendon fixation, and the Cayenne Mirror Partial Knee System for early-stage knee arthritis treatment. In the shoulder category, the Quattro System addresses rotator cuff and labral repairs. Cayenne Medical operates as a subsidiary of Zimmer Biomet Holdings, enhancing its capacity to deliver innovative medical solutions.
Spinal Restoration
Series B in 2007
Spinal Restoration, Inc. is a company focused on developing early intervention and minimally invasive therapies for chronic low back pain. Established in 2004 and headquartered in New York, it has created the Biostat System, which is designed to address chronic discogenic pain caused by internal disc disruptions. This system includes a resorbable biologic compound known as BIOSTAT BIOLOGX Fibrin Sealant, which acts as a tissue sealant, and a proprietary delivery device that administers the biologic directly to the intervertebral disc. The Biostat System aims to provide an effective treatment option for the significant population of adults—approximately four million—suffering from chronic low back pain.
KFx Medical
Series B in 2007
KFx Medical specializes in developing and manufacturing innovative soft tissue fixation implants tailored for orthopedic sports medicine. The company offers a range of products designed for tissue fixation, which can be directly placed into bones with or without sutures. These implants are applicable in various orthopedic surgical procedures, allowing surgeons to effectively reattach tissue in regions such as the shoulder, knee, foot, and ankle. KFx Medical collaborates closely with leading orthopedic surgeons to create advanced technologies and reliable surgical implants, ultimately aiming to improve surgical outcomes for patients.
BioSET
Venture Round in 2007
BioSET, Inc. specializes in the research and development of synthetic bioactive peptides aimed at enhancing bone and soft tissue repair. The company offers a range of medical devices, including AMPLEX, an implantable combination device designed for surgical bone graft applications in spine fusion and other orthopedic procedures. BioSET's product portfolio also includes innovations for sports medicine, peptide signaling molecules, and various scaffold biomaterials, all intended for use in musculoskeletal applications such as trauma, fracture repair, and soft tissue treatments. Founded in 2001 and based in Rockville, Maryland, BioSET operates as a subsidiary of Ferring Pharmaceuticals Inc.
Applied Spine Technologies
Series C in 2007
Applied Spine Technologies is a company based in Wellesley, Massachusetts, specializing in the design and development of medical devices focused on spine stabilization. The firm offers innovative solutions, including the Stabilimax Dynamic Spine Stabilization System, which functions as a posterior dynamic stabilization device. This system is designed to support patients with injured or degenerated spines while preserving natural motion, distinguishing it from traditional stabilization methods that often restrict movement. Through its specialized products, Applied Spine Technologies aims to improve treatment outcomes for individuals with spinal conditions.
Cayenne Medical
Series B in 2007
Cayenne Medical, Inc. is a medical device company specializing in soft tissue reconstruction solutions for the knee, shoulder, and extremities. Founded in 2005 and based in Scottsdale, Arizona, the company designs and markets a range of products aimed at improving surgical outcomes in sports medicine. Its offerings include the AperFix System, which facilitates anterior cruciate ligament (ACL) reconstruction using soft tissue grafts, as well as the AperFix II Cannulated Tibial Device and the AperFix Femoral Implant for anatomical soft tissue fixation. Cayenne Medical also provides the CrossFix II System for meniscal repair, the iFix for bone-tendon fixation, and the Cayenne Mirror Partial Knee System for early-stage knee arthritis treatment. In the shoulder category, the Quattro System addresses rotator cuff and labral repairs. Cayenne Medical operates as a subsidiary of Zimmer Biomet Holdings, enhancing its capacity to deliver innovative medical solutions.
Anulex Technologies
Series C in 2006
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
Kereos
Series B in 2005
Kereos, Inc. is a biopharmaceutical company based in Saint Louis, Missouri, specializing in the development of targeted molecular imaging agents and therapeutics aimed at detecting and treating cancer and cardiovascular diseases. Established in 1999, Kereos utilizes a nanoscale drug delivery technology that enhances the targeting and efficacy of various therapeutic compounds, including existing drugs, new candidates, and those that may be too toxic or fragile for conventional delivery methods. The company's product portfolio includes KER-1001, a cancer therapeutic that combines paclitaxel with a targeted nanodroplet, KER-1002, which integrates a natural anti-tumor agent, and KER-1003, known for its anti-angiogenic properties. Additionally, Kereos offers diagnostic solutions such as KER 0001, designed to detect angiogenesis. The company also collaborates with pharmaceutical and imaging firms to further develop its MRI agents and targeted chemotherapeutics for solid tumors and cardiovascular applications.
KFx Medical
Series A in 2005
KFx Medical specializes in developing and manufacturing innovative soft tissue fixation implants tailored for orthopedic sports medicine. The company offers a range of products designed for tissue fixation, which can be directly placed into bones with or without sutures. These implants are applicable in various orthopedic surgical procedures, allowing surgeons to effectively reattach tissue in regions such as the shoulder, knee, foot, and ankle. KFx Medical collaborates closely with leading orthopedic surgeons to create advanced technologies and reliable surgical implants, ultimately aiming to improve surgical outcomes for patients.
BrainsGate
Venture Round in 2005
BrainsGate, Ltd. is a medical device company based in Caesarea, Israel, specializing in therapies for patients with central nervous system diseases. The company has developed a technology platform that utilizes electrical stimulation of the spheno-palatine ganglion (SPG) to enhance cerebral blood flow. Currently, BrainsGate is focused on treating acute ischemic stroke through its innovative ischemic stroke system, which involves a miniature electrode implanted in the roof of the mouth during a minimally invasive procedure. This method is performed under local anesthesia and is comparable to standard dental treatments. The company has conducted several clinical trials, including a pivotal trial with 300 patients that validated the safety and efficacy of its treatment. BrainsGate is also engaged in a multi-national, randomized study known as ImpACT-24b, aimed at further assessing the effectiveness of its approach within a critical 24-hour window following a stroke.
Biomimetic Therapeutics
Series C in 2005
BioMimetic Therapeutics is a biotechnology company focused on developing biologically active drug-device combination products that stimulate the body's natural tissue regenerative processes. Founded in 1999 and headquartered in Franklin, Tennessee, the company offers a range of products targeting various orthopedic and sports medicine conditions. These include Augment Injectable and Augment Rotator Cuff, which are designed for applications such as foot and ankle fusions, wrist fracture healing, and rotator cuff tear surgical treatment. Additionally, the Augment Tendinopathy Injection addresses injuries related to tendon overuse. Through its innovative approaches, BioMimetic Therapeutics aims to improve healing outcomes for patients with skeletal and associated tissue injuries.
AxioMed
Series B in 2005
AxioMed LLC specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. Founded in 2001 and based in Malden, Massachusetts, the company was previously known as AxioMed Spine Corporation until its name change in 2014. AxioMed has developed the Freedom® Lumbar Disc and initiated clinical trials for its products, which are intended to improve the standard of care beyond traditional fusion and first-generation artificial discs. The company is led by CEO Patrick McBrayer and COO James Kuras, who oversee a team with extensive experience in spinal implants and engineering. They are supported by a Medical Advisory Panel of surgeons from prominent spine centers and universities. AxioMed's operations encompass product development, testing, clinical and regulatory affairs, and manufacturing, with ongoing projects focusing on cervical spine solutions.
Biomimetic Therapeutics
Series C in 2004
BioMimetic Therapeutics is a biotechnology company focused on developing biologically active drug-device combination products that stimulate the body's natural tissue regenerative processes. Founded in 1999 and headquartered in Franklin, Tennessee, the company offers a range of products targeting various orthopedic and sports medicine conditions. These include Augment Injectable and Augment Rotator Cuff, which are designed for applications such as foot and ankle fusions, wrist fracture healing, and rotator cuff tear surgical treatment. Additionally, the Augment Tendinopathy Injection addresses injuries related to tendon overuse. Through its innovative approaches, BioMimetic Therapeutics aims to improve healing outcomes for patients with skeletal and associated tissue injuries.
BioSET
Series B in 2004
BioSET, Inc. specializes in the research and development of synthetic bioactive peptides aimed at enhancing bone and soft tissue repair. The company offers a range of medical devices, including AMPLEX, an implantable combination device designed for surgical bone graft applications in spine fusion and other orthopedic procedures. BioSET's product portfolio also includes innovations for sports medicine, peptide signaling molecules, and various scaffold biomaterials, all intended for use in musculoskeletal applications such as trauma, fracture repair, and soft tissue treatments. Founded in 2001 and based in Rockville, Maryland, BioSET operates as a subsidiary of Ferring Pharmaceuticals Inc.
Alveolus
Series B in 2004
Alveolus specializes in non-vascular interventional stenting technology aimed at providing innovative solutions for pulmonary and gastrointestinal applications, as well as ancillary products. The company develops advanced stents that create artificial pathways and support structures for hollow organs that have become obstructed due to cancerous lesions or benign conditions. By offering these technologies, Alveolus enhances the capabilities of interventional pulmonologists, gastroenterologists, and radiologists, facilitating improved treatment options for patients facing these medical challenges.
Salient Surgical Technologies
Series D in 2003
Salient Surgical Technologies, Inc., established in 1999, is a privately held medical technology company that specializes in advanced energy devices for surgical procedures. Initially focusing on monopolar electrosurgical devices for liver cancer treatment, the company has since developed the AQUAMANTYS® System, which features bipolar electrosurgical technology. This system is designed to minimize surgical blood loss through its patented TRANSCOLLATION® technology, which enables the haemostatic sealing of soft tissue and bone. The AQUAMANTYS System is utilized in various surgeries, including orthopaedic reconstruction, spine surgery, orthopaedic trauma, and surgical oncology. Salient's products are distributed in the United States, Europe, and Asia, benefiting hospitals, healthcare providers, and patients by enhancing clinical outcomes and reducing costs. To date, over 500,000 patients have undergone treatment using TRANSCOLLATION technology.
GTx
Series E in 2003
GTx, Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of innovative treatments for stress urinary incontinence and prostate cancer. The company specializes in selective androgen receptor modulators (SARMs) and selective androgen receptor degraders, targeting conditions such as breast cancer and Duchenne muscular dystrophy. One of its notable product candidates is enobosarm GTx-024, which is undergoing Phase II clinical trials for patients with specific types of breast cancer and postmenopausal women suffering from stress urinary incontinence. Founded in 1997 and based in Memphis, Tennessee, GTx aims to advance medical solutions by leveraging new scientific approaches. In 2019, GTx was acquired by Oncternal Therapeutics in a reverse merger.
Biomimetic Therapeutics
Series B in 2003
BioMimetic Therapeutics is a biotechnology company focused on developing biologically active drug-device combination products that stimulate the body's natural tissue regenerative processes. Founded in 1999 and headquartered in Franklin, Tennessee, the company offers a range of products targeting various orthopedic and sports medicine conditions. These include Augment Injectable and Augment Rotator Cuff, which are designed for applications such as foot and ankle fusions, wrist fracture healing, and rotator cuff tear surgical treatment. Additionally, the Augment Tendinopathy Injection addresses injuries related to tendon overuse. Through its innovative approaches, BioMimetic Therapeutics aims to improve healing outcomes for patients with skeletal and associated tissue injuries.
TriVirix International
Series D in 2002
TriVirix International is a U.S.-based manufacturer and designer of electro-mechanical medical devices, diagnostic tools, and life-science equipment. Headquartered in Milaca, Minnesota, the company specializes in producing a range of products, including ribo printers, point-of-care blood testing analyzers, volumetric infusion pumps, and vital sign monitors. TriVirix International focuses on delivering innovative solutions for the healthcare industry, addressing the needs of medical professionals and enhancing patient care through advanced technology.
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