PHX Ventures is a venture capital firm based in Tempe, Arizona. It concentrates on seed-stage B2B software companies across Arizona and operates a venture studio to build SaaS businesses.

Moonshots Capital is a venture capital firm based in Austin, Texas, founded in 2017. It focuses on seed and early-stage technology startups with moonshot potential, investing in areas such as dual-use technologies, fintech, consumer internet, artificial intelligence, and cybersecurity. The firm emphasizes a disciplined investment process to identify founders pursuing large, growing markets and products with the potential to redefine their sectors. Moonshots Capital operates as a registered investment adviser, aligning its practices with investor interests and maintaining a rigorous, research-driven approach to opportunity evaluation. The firm backs teams seeking ambitious, scalable solutions that can transform work and everyday life.

AZ Venture Capital is a Phoenix-based venture capital investment firm that backs early-stage technology startups and funds across enterprise software, consumer technology, climate-tech, and bio/health tech. It invests in pre-seed through Series B rounds and concentrates on Arizona startups, including medical devices, diagnostics, therapeutics, software, and green tech, with a focus on founders from traditionally underserved communities and on expanding access to equity and entrepreneurship in the state.

Grayhawk Capital is a Scottsdale-based investment firm focused on technology and healthcare companies in the United States. Founded around 1999, it funds early and growth-stage ventures, typically taking minority positions and often co-investing with other funds. The firm targets software as a service, cloud, cybersecurity, enterprise software, fintech, business intelligence, health tech, and information technology sectors, with a regional emphasis on the Southwest United States. Investments are generally managed for three to seven years and pursue exits through strategic acquisitions or public offerings. The firm seeks management teams with track records and aims to back companies with scalable, disruptive products.

In Revenue Capital is a Scottsdale, Arizona-based venture capital firm founded in 2023. It partners with other venture capital firms to identify and co-invest in early-stage B2B vertical SaaS startups, and it combines go-to-market expertise with capital to help founders grow and succeed.

Research Corporation Technologies is a venture capital firm based in Tucson, Arizona, founded in 1987, focused on investing in technology companies in the medical device, therapeutic, and biotechnology sectors.

Brookstone Partners is a private equity firm based in New York that seeks to acquire and invest in North American companies across sectors including B2B, B2C, healthcare, manufacturing and industrials.

Pivotal Group is an investment and development firm based in Phoenix, Arizona, focusing on real estate across all asset classes. With more than twenty-five years in the industry, it pursues private equity and real estate investments, including niche residential projects, commercial development, master-planned communities, luxury hotels and spa properties, and office and resort assets. The firm emphasizes creativity, precision, and value creation through development, acquisitions, and asset management, and operates across the United States and Canada.

MRTNZ Ventures is an investment firm founded in 2014 and based in Paradise Valley, Arizona, described as a family office that pursues early- and seed-stage investments.

Illuminated Funds Group is a venture capital firm based in Cave Creek, Arizona, founded in 2006, focused on minority investments in seed-, early-, and later-stage companies.

Trinity Capital is a specialized lending firm that provides venture debt and related financing to emerging growth and venture-backed technology companies in the United States. Working with venture capital firms, technology banks, and portfolio companies, it offers debt solutions that include senior and subordinated loans, asset-backed financings, equipment leases and financing, and lines of credit, with the aim of preserving equity for founders and investors. The firm targets growth-stage and early-stage technology companies across sectors such as software, hardware, healthcare, semiconductors, energy, and telecommunications, and it often funds alongside syndicate partners. Based in Arizona with offices in Phoenix and Chandler, Trinity Capital emphasizes flexible structures, customized terms, and expertise in equipment financing and venture debt to support rapid scale, acquisitions, and buyouts when appropriate. The firm also manages SBIC funds as part of its investment activities.

DFE Capital Management, established in 2019 and based in Phoenix, Arizona, serves as the direct investing arm of DF Enterprises. The firm adopts an opportunistic investment strategy, focusing on later-stage and growth-stage private businesses across sectors such as B2B, advanced manufacturing, industrial, and technology. DFE Capital Management seeks to partner with high-quality companies poised to disrupt expanding markets, prioritizing those with strong management teams and a committed investor base.

DVI Equity Partners is a venture capital firm founded in 2018 and based in the Southwest United States. It focuses on micro-cap and early-stage technology investments, often serving as first institutional money in Series A rounds. The target sectors include information technology, big data, cybersecurity, artificial intelligence, machine learning, and fintech. While there is a geographic preference for the Southwest (California, Arizona, New Mexico, Texas, Nevada, Colorado, Utah), fit and growth potential drive opportunities beyond location. The firm emphasizes strategic value and support to help portfolio companies scale, rather than capital alone.

Biltmore Ventures is an early-stage venture capital firm founded in 2006 and based in Phoenix, Arizona. It targets investments in companies with a strong internet component, including social networks and those operating in the decentralized distribution sector.

DWP Capital is a venture capital firm founded in 2016 and based in Scottsdale, Arizona. It focuses on early-stage software investments, particularly in vertical software and tech-enabled services.

Alliance Healthcare Partners is a Scottsdale, Arizona-based venture capital firm founded in 2012 that invests in innovative healthcare technology and service companies. Comprised of serial entrepreneurs, the firm brings deep industry knowledge and resources to transforming healthcare by supporting cutting-edge technologies and business models that enhance transparency, efficiency, and quality of care while optimizing the use of resources.

UAVenture Capital, LLC is a venture capital firm founded in 2017 and located in Tucson, Arizona. The firm focuses on early-stage and growth capital investments specifically in companies connected to the University of Arizona. UAVenture Capital aims to finance the commercialization of innovations developed by faculty members, students, and colleagues affiliated with the university, which is recognized as a leading research institution. The firm primarily invests in the science and technology sectors, supporting ventures that leverage academic research to create impactful products and services.

GlobalLink1 Capital is a private equity investment firm based in Phoenix, Arizona, founded in 2015, that engages in long-term investments across asset classes including private equity, venture capital, strategic financing, and private REITs, as well as lending and leveraged investments, and provides real estate financing for commercial and residential properties.

Vye Ventures is a venture capital firm founded in 2021 and based in Scottsdale, Arizona. It pursues private investments in healthcare, biotechnology, climate and clean technology, and other deep tech sectors, including medical devices and hardware.

Beechtree Capital is a private investment firm focusing on venture capital and private equity investments. Founded in 1992 and based in New York and Scottsdale, it participates in mezzanine, emerging growth, and mature-stage opportunities, typically investing between $1 million and $10 million and often serving as a lead investor or working in syndicates. The firm engages across sectors such as energy, ecological, sports, entertainment, and medical, and provides advisory and investment services to entrepreneurs and established companies to realize growth and innovation in the U.S. and international markets. Beechtree Capital maintains activity in New York City, Scottsdale, Zurich, and Dubai and leverages relationships with family offices, venture firms, investment banks, and other professionals to finance strategic initiatives.

Roundsquare Ventures is a venture capital firm founded in 2015 and based in Scottsdale, Arizona. It focuses on early-stage investments, providing capital to innovative startups to support product development and market entry, typically up to one million dollars.

Sustainable Conversion Ventures is a venture capital firm founded in 2013, based in Arizona, that invests in technology, renewable fuels, and chemicals companies.

Cicada Capital is a venture capital firm based in Scottsdale, Arizona, that focuses on seed-stage investments and debt financing.

GTMFund is a venture capital firm based in Scottsdale, Arizona, founded in 2020. It concentrates on early-stage investments in hyper-growth B2B SaaS companies and supports portfolio founders with GTM strategy, talent hiring, and execution. The firm leverages a network of more than 260 go-to-market executives drawn from fast-growing technology companies such as Snowflake, DocuSign, Okta, Salesforce, Twilio, Square, and Procore to help companies scale. Through capital plus hands-on GTM resources, GTMFund aims to accelerate growth and help early-stage B2B SaaS ventures reach scale quickly.

PerformanceEdge Partners is a Scottsdale, Arizona-based venture capital and value acceleration firm established in 2008. It focuses on post-startup technology companies, offering coaching, growth support and equity management to help them scale and increase value. The firm engages in investing in small technology-focused businesses and provides strategic guidance to accelerate development and market positioning.

True North Venture Partners is a venture capital firm that funds early- and late-stage companies in cleantech and sustainability sectors, including energy, water, agriculture, waste, and low-carbon infrastructure. The firm often acts as a first investor and provides capital plus strategic guidance to help portfolio companies scale disruptive innovations such as advanced fuels, chemicals, and waste-harvesting solutions. With a presence in Chicago, Illinois, and Phoenix, Arizona, it sources opportunities across North America. Investment sizes vary, and the firm can participate in rounds from seed to growth, reflecting a flexible approach to support companies capitalized for scale.

Xcellerant Ventures is a venture capital firm based in Scottsdale, Arizona. It focuses on early-stage healthtech and medtech companies, supporting disruptive startups that aim to expand access, reduce costs per patient, and improve treatment quality. The firm seeks to advance healthcare innovation through strategic backing of promising medical technologies.

Established in 2006, Menagerie Investments is a venture capital firm headquartered in Chandler, Arizona. It focuses on investing in seed and early-stage companies.

Cancer Fund, established in 2018 and based in Phoenix, Arizona, is a venture capital firm focused on advancing innovations in cancer treatment and management. The firm seeks to generate both impact and financial returns by supporting startups that are developing new therapies, diagnostics, and preventive technologies. With a commitment to enhancing patient outcomes, increasing access to care, and reducing healthcare costs, Cancer Fund aims to invest up to $30 million from pre-seed to Series D stages. The firm facilitates the progression of cancer innovations through regulatory approvals, technical validation, and early market adoption, positioning itself as a key player in the fight against cancer.

Exit Capital is a venture capital firm founded in 2021 and based in Phoenix, Arizona, focused on investing in early-stage technology companies.

Social Leverage is a Scottsdale, Arizona-based venture capital partnership that invests in early-stage technology companies across the United States. The firm focuses on software, consumer, and fintech opportunities, evaluating potential investments with a fundamentals-driven approach informed by two decades of domain experience building, valuing, and selling companies. Social Leverage partners with exceptional entrepreneurs and management teams to back capital-light companies with viable products and large addressable markets. It has invested in more than 30 early-stage web businesses and typically writes checks in the range of $100,000 to $500,000.

Flywheel Ventures is a Santa Fe-based venture capital firm that funds seed to early-stage technology companies, with a regional emphasis on the Southwest and Rocky Mountain states. The firm backs information technology, software and related sectors, including B2B products, software-as-a-service, semiconductors, networking, data services, and other technology domains, and seeks to invest in companies with solutions addressing global IT and urban systems challenges. It maintains offices in Albuquerque and San Francisco and typically acts as a lead investor, aiming to take a board seat and to syndicate for follow-on financing. While focused on the United States, its regional roots are in New Mexico, Colorado and Arizona, with investment activity also in California. Flywheel pursues seed-to-early-stage opportunities and up to growth capital for portfolio companies, collaborating with other firms to support scale.

Founded in 2021, RevTek Capital is a boutique asset manager specializing in tailored credit solutions for SaaS technology companies and other high-growth recurring revenue businesses. It offers flexible, founder-friendly debt capital ranging from $3 million to $30 million, designed to maximize enterprise value while minimizing dilution. RevTek caters to established growth companies with proven track records, providing attractive, uncorrelated returns to investors.

Sonoran Founders Fund is a venture capital firm founded in 2020 and based in Scottsdale, Arizona, specializing in early-stage investments in the Southwest United States. It targets information technology, software-as-a-service, artificial intelligence and machine learning, fintech, education technology, health tech, and marketplaces, with typical checks ranging from USD 0.5 million to 1 million.

Agility Ventures is the corporate venture capital arm of Agility, based in Prescott, Arizona. Founded in 2004, it invests in seed-, early-, and later-stage companies across sectors including business products and services, consumer products and services, financial services, information technology, and other technology-driven areas such as big data, blockchain, cryptocurrency, artificial intelligence, and machine learning, with a focus on opportunities in the United States.

Crossover VC is a venture capital investment firm based in Phoenix, Arizona, established in 2019. The firm provides diversified exposure to the private technology sector by investing in pre-seed and seed funds that serve as the first call for today's top founders, as well as select early-stage direct opportunities. It concentrates on backing small funds led by founders or operators of tech unicorns with proven investing track records, enabling a direct line between operating experience and early founder access. The investor base comprises traditional limited partners and notable athletes and entertainers, supporting portfolio managers and founders with decades of operating and investing experience.

VRG Capital is a private equity investment firm based in Toronto, Canada. It focuses on financing and growing small and mid-sized companies across healthcare, financial services, information technology, logistics, insurance, and marketing or sales services, as well as other diversified sectors. The firm provides capital and management experience, pursuing minority and majority stakes through growth equity, buyouts, and strategic advisory services. It operates with a regional and international footprint, including offices in Toronto, Vancouver and Phoenix, and engages in providing capital for startups and expansions, acquisitions and mergers, while supporting portfolio companies with operational guidance.

Frazier VC is a Utah-based venture capital firm focused on backing B2B SaaS and vertical software leaders. Based in the Silicon Slopes, it allocates a large share of its capital to Utah startups while pursuing opportunities across the Mountain West, including Colorado, Idaho, Arizona, and Nevada. The firm partners with founders building platforms poised for digital transformation, helping early-stage companies scale from local innovators to category leaders. Its investment focus is mission-critical B2B software with high retention and compounding growth, primarily in SaaS and cloud platforms, and it typically targets seed to Series A rounds.

NGP Energy Capital Management is a private investment firm focused on energy. Founded in 1988 and based in Irving, Texas, it manages a family of private equity funds and makes direct equity investments across the oil and gas value chain, including production, acquisition, exploration and development drilling, midstream services, energy efficiency, and power technology, as well as related energy businesses. The firm also pursues opportunities in water resources and services, food and agriculture, and coastal protection. It primarily targets North American companies, including the United States, Canada, and parts of the Caribbean and Central America, with typical investment sizes from 2 million up to 500 million dollars. It may co-invest in direct oil and gas property interests alongside portfolio companies and maintains offices in Houston, London, Santa Fe, and Stamford to support a broad geographic reach.

Greycroft is a venture capital firm based in New York and Los Angeles that concentrates on technology startups, with a focus on the Internet and mobile markets. The firm uses its extensive media and technology industry connections to help entrepreneurs gain visibility, build strategic relationships, bring products to market, and scale successful businesses. Since inception Greycroft has invested in more than 200 companies and manages over $1 billion in capital. Its investment scope spans consumer internet, fintech, healthcare, and enterprise software, reflecting a broad approach to funding early- and growth-stage ventures in technology sectors.

G Squared is a Chicago-based venture capital investment firm founded in 2011. The firm backs companies across B2B and B2C sectors, including software, fintech, insurtech, mobility, SaaS, IoT, e-commerce and data technologies, with a broad focus on growth and technology-enabled services. It aims to support private companies as they stay private longer by providing both primary capital to fuel growth and transitional capital to facilitate liquidity for early investors, employees and other sellers. G Squared partners with portfolio companies throughout their lifecycle, adopting a differentiated approach from traditional venture firms. The firm has backed well-known consumer and enterprise platforms such as 23andMe, Coursera, Instacart, Lyft, Pinterest and Spotify, along with next-generation disruptors like Asana, Blend, Brex, Capsule, Flexport, Impossible Foods, Toast and Turo.

Revolution is a Washington, DC-based investment firm founded in 2005 by Steve Case that focuses on private equity and growth capital across sectors including technology, financial services, media and entertainment, health, and consumer products. The firm manages a family of funds, including Revolution Ventures for early-stage technology investments and Revolution Growth for growth-stage opportunities, and operates Rise of the Rest to discover and fund startups outside traditional hubs. With offices in Washington, DC and San Francisco, Revolution partners with entrepreneurs and regional ecosystem leaders to back scalable companies and broaden geographic opportunity for American startups, often pursuing substantial investments and collaborating with other top-tier investors.

Prelude Ventures is a San Francisco-based venture capital firm founded in 2013 that backs early-stage startups with the potential to mitigate climate change. It focuses on investments across sectors including advanced energy, food and agriculture, transportation and logistics, advanced materials and manufacturing, and computing, supporting the development of category-defining businesses in these areas.

Clearvision Ventures is a venture capital firm based in Menlo Park, California, founded in 2015. It backs software companies across the internet of things, big data, and security sectors, seeking opportunities to drive category leadership. The firm invests between 1 million and 10 million dollars in a single company at any stage, providing capital to help entrepreneurs build scalable, market-leading businesses.

MedTech Venture Partners is a venture capital firm that provides funding and support to medical technology entrepreneurs. With a team that has extensive experience in overseeing the development and launch of over 30 medical devices and diagnostics products, the company focuses on scaling early stage device businesses and leveraging clinical and regulatory expertise globally. Additionally, they have been involved in buying and selling technologies, products, and companies, enhancing their ability to understand and assist device entrepreneurs in achieving success. Working in collaboration with partners at UCSF, MedTech Venture Partners is dedicated to building a thriving ecosystem around early stage medical devices.

Uncorrelated Ventures is a venture capital firm founded in 2019 by Salil Deshpande and headquartered in San Francisco, California. It backs early-stage companies focused on infrastructure software and seeks opportunities in related areas such as decentralized finance, cryptocurrency, blockchain, and fintech.

Ulu Ventures is a Palo Alto, California-based seed- and early-stage venture capital firm focused on technology-driven startups across IT, software, internet-enabled services, EdTech, FinTech, IoT, digital media, and related sectors in the United States, with a Bay Area emphasis. Founded in 2008, the firm backs diverse entrepreneurial teams and frequently co-invests with other angels or venture funds in early rounds. Ulu is noted as the first Latina-led venture fund in Silicon Valley and is among the largest in the country by assets under management, with over $200M.

Curaleaf is a vertically integrated cannabis operator providing medical and adult-use products in the United States. The company cultivates, processes, markets, and dispenses cannabis in multiple forms, including flowers, pre-rolls, vape pens, and topical products, under brands such as Curaleaf, Select, and Grassroots. It serves both consumer markets and licensees through cultivation, processing, and back-office services, and engages in related activities such as intellectual property licensing, real estate leasing, and lending facilities under management agreements. The business has expanded through acquisitions that broaden its footprint in the United States and into Europe, and operates across numerous states with a broad product portfolio including oils, concentrates, tinctures, and hemp-based CBD products. By emphasizing clarity around cannabis and confidence around consumption, Curaleaf aims to improve user accessibility and convenience across medical and adult-use channels.

MVM Life Science Partners is a London-headquartered private equity firm with an office in Boston that focuses on life sciences and healthcare. Founded in 1997, it targets early-stage and growth opportunities in medical technology, biotechnology and healthcare services, including diagnostics, drug delivery, gene therapy, vaccines, medical devices, life science tools and digital health. The firm pursues investments across Europe and North America, supporting companies with differentiated technology and substantial market potential, often taking active ownership to help scale operations and expand globally.

Stout Street Capital is a Denver, Colorado-based venture capital firm that backs early-stage technology companies. It concentrates on software and B2B SaaS, while also investing in fintech, advanced materials, robotics, and artificial intelligence. The firm targets opportunities in under-served markets in the central United States, with a particular emphasis on the Rocky Mountain region. Its approach combines data-driven analysis, market assessment, and thorough due diligence to select ventures that can improve efficiency and generate measurable value as they scale.