Malaysian Life Sciences Capital Fund I

Malaysian Life Sciences Capital Fund I, based in Kuala Lumpur, is a venture capital firm co-managed by Xeraya Capital and Spruce Capital Partners. It focuses on early-stage investments in the life sciences and biotechnology sectors.

Roger Wyse Ph.D

Founder and Co-Chairman

16 past transactions

Crop Enhancement

Series B in 2016
Crop Enhancement LLC is an early-stage specialty materials company based in San Jose, California, founded in 2011. The company focuses on developing innovative anchoring and controlled-release formulation technologies for agricultural chemicals. Its advanced agrochemical formulations utilize environmentally friendly chemistry to enhance crop yields and profitability while minimizing the reliance on synthetic pesticides. Crop Enhancement's products include proprietary films that modify plant surfaces, improving resistance to pests and diseases. This approach not only supports sustainable farming practices but also enables precise delivery of active ingredients and fertilizers, ultimately benefiting growers through increased efficiency and reduced chemical use.

LanzaTech

Series D in 2014
Founded in 2005, LanzaTech is a pioneering carbon recycling company that converts industrial waste gases into fuel ethanol and other valuable products. Its innovative bio-catalytic toolkits enable gas fermentation microbes to recycle carbon emissions from sources like steel mills and landfills, reducing reliance on fossil fuels and supporting a circular economy.

LanzaTech

Series C in 2013
Founded in 2005, LanzaTech is a pioneering carbon recycling company that converts industrial waste gases into fuel ethanol and other valuable products. Its innovative bio-catalytic toolkits enable gas fermentation microbes to recycle carbon emissions from sources like steel mills and landfills, reducing reliance on fossil fuels and supporting a circular economy.

FLEXIROAM

Grant in 2013
Flexiroam Limited is a mobile data operator based in Petaling Jaya, Malaysia, that specializes in providing voice and data roaming services to travelers across multiple continents, including Africa, Asia, Europe, North America, South America, Oceania, and Antarctica. The company offers a range of products designed to enhance connectivity for both individual travelers and enterprises. Its flagship product, Flexiroam X, is an app that facilitates data connectivity while traveling, allowing users to make and receive unlimited international roaming calls. FLEXI+ provides data backing services tailored for businesses, while XACE offers programmable data connectivity solutions for Internet of Things applications and SuperApps. Flexiroam has established a partnership with Mastercard to further enhance its service offerings. Founded in 2010, the company continues to focus on innovative solutions to meet the growing demands of global travelers.

Akermin

Venture Round in 2013
Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that enable the integration of enzymes into traditional chemical absorption processes for effective CO2 removal. In addition to its primary focus on carbon capture, Akermin is also exploring applications of its stabilized enzyme technology in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The company aims to commercialize its technology, which originated from research at Saint Louis University, and has demonstrated its capabilities in developing sustainable solutions for a range of industries.

Segetis

Series C in 2012
Segetis, Inc. is a green chemistry company based in Golden Valley, Minnesota, specializing in the development, production, and commercialization of renewable polymers. Founded in 2006, Segetis focuses on a platform of binary monomers derived from renewable feedstocks, including non-food agricultural and forestry materials. The company's innovative technology supports the production of a range of industrial bioproducts such as bio-plastics, surfactants, plasticizers, adhesives, and coalescent solvents, catering to specialty chemical applications. Segetis's chemistries create opportunities for product enablement and synergies across various industries, including those involved in the processing of starch, sugar crops, wood, cellulose, and paper pulp, as well as the chemical processing of vegetable oils and the manufacturing of biodiesel and linear alpha-olefins.

Glori Energy

Series C in 2012
Glori Energy Inc is a development stage company focused on enhancing oil recovery from existing well reservoirs without the need for new drilling. The company collaborates with oil producers to implement its proprietary AEROTM (Activated Environment for Recovery of Oil) System, which aims to significantly boost oil production. This innovative system provides a low-cost and environmentally friendly solution for recovering billions of barrels of oil that were previously trapped, thereby facilitating a more sustainable approach to oil extraction.

Chromatin

Series D in 2011
Chromatin is a biotech company focused on developing and marketing innovative technologies and products across agricultural, energy, chemical, nutritional, and pharmaceutical sectors. The company specializes in hybrid, drought-tolerant sorghum seeds, utilizing advanced breeding methodologies to create next-generation sorghum that meets the rising demand for sustainable agricultural practices. By combining diverse sorghum varieties, Chromatin produces seeds that can thrive on more than 80% of the world's agricultural land, supporting farmers in optimizing crop production for both traditional agriculture and bio-industrial applications. The company aims to address key societal challenges, enhancing agricultural productivity and contributing to renewable energy resources.

Cobalt Technologies

Series D in 2011
Cobalt Technologies is a biotechnology company founded in 2005 and headquartered in Mountain View, California. The company specializes in developing innovative technologies for the production of biofuels, particularly focusing on next-generation bio n-butanol. Cobalt's advancements enable the creation of low-cost, commercial-scale biobutanol, which serves as a sustainable alternative to petroleum-based products. This bio-based chemical can be utilized in a wide range of applications, including fuels, jet fuel, bio-based plastics, synthetic rubber, paints, adhesives, and solvents. By providing cost-effective substitutes to traditional petroleum-derived chemicals, Cobalt Technologies aims to contribute to cleaner burning fuels and a reduced environmental impact.

Akermin

Series B in 2010
Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that enable the integration of enzymes into traditional chemical absorption processes for effective CO2 removal. In addition to its primary focus on carbon capture, Akermin is also exploring applications of its stabilized enzyme technology in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The company aims to commercialize its technology, which originated from research at Saint Louis University, and has demonstrated its capabilities in developing sustainable solutions for a range of industries.

Segetis

Series B in 2010
Segetis, Inc. is a green chemistry company based in Golden Valley, Minnesota, specializing in the development, production, and commercialization of renewable polymers. Founded in 2006, Segetis focuses on a platform of binary monomers derived from renewable feedstocks, including non-food agricultural and forestry materials. The company's innovative technology supports the production of a range of industrial bioproducts such as bio-plastics, surfactants, plasticizers, adhesives, and coalescent solvents, catering to specialty chemical applications. Segetis's chemistries create opportunities for product enablement and synergies across various industries, including those involved in the processing of starch, sugar crops, wood, cellulose, and paper pulp, as well as the chemical processing of vegetable oils and the manufacturing of biodiesel and linear alpha-olefins.

Gevo

Venture Round in 2009
Gevo specializes in producing renewable fuels and chemicals using sustainable resources. Its primary products include gasoline, jet fuel, diesel fuel, isobutanol, and renewable natural gas. The company aims to reduce greenhouse gas emissions by providing low-carbon alternatives to fossil fuels.

Small Bone Innovations

Series D in 2009
Small Bone Innovations (SBi) is a medical device company specializing in the design, manufacture, and distribution of implants tailored for small bones and joints. Their product portfolio focuses on trauma and arthroplasty applications, catering specifically to the thumb, hand, wrist, elbow, foot, and ankle regions. SBi's offerings include basal joint arthritis treatments and implants designed to replace anatomic joint surfaces while preserving bones and minimizing disruption to collateral ligaments and soft tissues.

Cobalt Technologies

Series C in 2008
Cobalt Technologies is a biotechnology company founded in 2005 and headquartered in Mountain View, California. The company specializes in developing innovative technologies for the production of biofuels, particularly focusing on next-generation bio n-butanol. Cobalt's advancements enable the creation of low-cost, commercial-scale biobutanol, which serves as a sustainable alternative to petroleum-based products. This bio-based chemical can be utilized in a wide range of applications, including fuels, jet fuel, bio-based plastics, synthetic rubber, paints, adhesives, and solvents. By providing cost-effective substitutes to traditional petroleum-derived chemicals, Cobalt Technologies aims to contribute to cleaner burning fuels and a reduced environmental impact.

Gevo

Series C in 2008
Gevo specializes in producing renewable fuels and chemicals using sustainable resources. Its primary products include gasoline, jet fuel, diesel fuel, isobutanol, and renewable natural gas. The company aims to reduce greenhouse gas emissions by providing low-carbon alternatives to fossil fuels.

Light Sciences Oncology

Series B in 2007
Light Sciences Oncology, Inc. is a biotechnology company focused on developing and manufacturing talaporfin sodium, a water-soluble drug for the treatment of solid tumors and other medical indications. The company specializes in providing innovative oncology solutions, including a single-use, LED-based drug activator that delivers a precise light dose to enhance treatment efficacy. Its primary applications include the treatment of hepatocellular carcinoma, metastatic colorectal cancer, and benign prostatic hyperplasia. Founded in 1994 and headquartered in Bellevue, Washington, Light Sciences Oncology combines advanced drug development with a commitment to improving patient care through non-invasive treatment options.
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