Ajax Health is a private equity and venture capital firm established in 2017, with headquarters in Menlo Park, California, and an additional office in New York City. The firm specializes in all stages of a company's lifecycle, focusing on innovative medical device companies, medtech, healthcare services, digital health, biotechnology, and healthcare IT. Ajax Health aims to accelerate medical innovation by investing in solutions that address significant challenges in the healthcare sector. Through its strategic investments, the firm seeks to foster advancements that improve patient outcomes and enhance care delivery.
XII Medical is a medical device developer focused on creating innovative solutions for obstructive sleep apnea. The company has developed a minimally invasive outpatient technology that includes an implantable neurostimulation device designed to alleviate the condition. This device works by preventing the muscles in the throat from relaxing during sleep, thereby avoiding airway blockage and enabling patients to enhance oropharyngeal airflow. Through its advancements in sleep apnea treatment, XII Medical aims to improve patient outcomes and provide a proactive approach to managing this common sleep disorder.
Cortica
Series D in 2023
Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.
AcuityMD
Series A in 2022
AcuityMD is a company that offers a medical technology software platform aimed at enhancing the commercialization and effectiveness of medical devices through data-driven insights. The platform facilitates a clearer understanding of the medical products used in patient treatment, enabling device manufacturers to expand their market reach. By integrating strategic and market insights, AcuityMD's solution supports collaboration across various functions within medical companies, fostering stronger relationships between these companies and the healthcare professionals they serve.
XII Medical
Series A in 2022
XII Medical is a medical device developer focused on creating innovative solutions for obstructive sleep apnea. The company has developed a minimally invasive outpatient technology that includes an implantable neurostimulation device designed to alleviate the condition. This device works by preventing the muscles in the throat from relaxing during sleep, thereby avoiding airway blockage and enabling patients to enhance oropharyngeal airflow. Through its advancements in sleep apnea treatment, XII Medical aims to improve patient outcomes and provide a proactive approach to managing this common sleep disorder.
Third Harmonic Bio
Series B in 2022
Third Harmonic Bio is a clinical-stage biopharmaceutical company dedicated to developing innovative treatments for severe allergies and inflammation. The company is focused on creating first-in-class oral small-molecule inhibitors targeting the KIT receptor, which plays a crucial role in the survival and function of mast cells—key immune cells involved in allergic responses. Its lead product candidate, THB001, is designed to provide selective inhibition of KIT, while another candidate, THB335, aims to address multiple mast cell-driven inflammatory diseases affecting the skin, respiratory system, and gastrointestinal tract. Through its research and development efforts, Third Harmonic Bio seeks to advance the management of inflammatory diseases, enhancing patient outcomes and quality of life.
AcuityMD
Seed Round in 2021
AcuityMD is a company that offers a medical technology software platform aimed at enhancing the commercialization and effectiveness of medical devices through data-driven insights. The platform facilitates a clearer understanding of the medical products used in patient treatment, enabling device manufacturers to expand their market reach. By integrating strategic and market insights, AcuityMD's solution supports collaboration across various functions within medical companies, fostering stronger relationships between these companies and the healthcare professionals they serve.
Treeline Biosciences
Series A in 2021
Treeline Biosciences is a biotechnology company established in 2021 and based in Stamford, Connecticut. The company focuses on developing transformative precision medicines aimed at treating cancer and other serious health conditions. Utilizing a comprehensive drug discovery platform, Treeline combines mechanistic biology, medicinal chemistry, computational science, structural biology, and protein science to create innovative therapeutic solutions. Through its research and development efforts, Treeline aims to provide effective treatments to improve patient outcomes in oncology and beyond.
Atriomx
Series A in 2020
Atriomx is a medical technology company focused on enhancing the understanding and treatment of cardiac arrhythmias, particularly atrial fibrillation. The company has developed a non-invasive clinical solution that employs advanced data science and proprietary algorithms to deliver in-depth electrophysiology insights. This innovative approach allows for the detection and characterization of underlying disease mechanisms in patients, thereby providing critical information to healthcare professionals. By equipping doctors with comprehensive insights into a patient's condition, Atriomx aims to facilitate informed decision-making regarding treatment options, potentially reducing the need for costly and invasive procedures.
Protaryx
Series A in 2020
Protaryx Medical Inc. is a medical device company focused on developing advanced transseptal access devices for minimally invasive cardiac procedures. Founded in 2019 and headquartered in Baltimore, Maryland, with engineering operations in Minneapolis, Minnesota, the company aims to enhance access to the left atrium during transcatheter interventions. Its innovative device facilitates precise and rapid septal crossing, providing surgeons with reliable access for catheter-based therapies. By prioritizing meaningful improvements, Protaryx Medical seeks to benefit both healthcare professionals and patients in the realm of cardiac care.
Cortica
Venture Round in 2020
Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.
Verix Health
Series A in 2019
Verix Health is focused on creating a range of steerable surgical devices designed for minimally invasive diagnosis and treatment of hard-to-reach lesions in the human body. Founded by Professor Mark Yim and PCI Ventures at the University of Pennsylvania, the company is incubated at the Pennovation Center in Philadelphia. Its innovative products aim to provide access and control for accurately targeting cancer in challenging anatomical locations, thereby allowing patients to receive effective treatments for tumors that are difficult to access through traditional surgical methods.
EPMap-System
Series A in 2019
EPMap-System specializes in heart diagnosis technologies with a focus on electrophysiology procedures. With over 20 years of experience, the company offers EPPerfect, a comprehensive solution that integrates recording, stimulation, navigation, and ablation functionalities for cardiac applications. EPPerfect features a 3D mapping and navigation system, combined with an integrated signal recording and pacing system, a radiofrequency ablation generator, and an irrigation pump. This advanced technology allows hospitals to access high-density mapping and to accurately tag anatomical structures, thereby enhancing patient care and procedural outcomes. Additionally, EPPerfect can be seamlessly integrated with other solutions, further expanding its utility in the field of electrophysiology.
Ablacon
Series A in 2019
Ablacon Inc. is a company based in Wheat Ridge, Colorado, that specializes in developing machine intelligence systems aimed at understanding and treating atrial fibrillation (AF). Founded in 2015, Ablacon's technology provides real-time visualization of electrographic flow within the cardiac chambers, enabling the localization and characterization of AFib sources. This advanced system allows healthcare professionals to guide targeted therapies with greater speed, precision, and reliability, thereby improving patient outcomes in the management of atrial fibrillation.
EPIX Therapeutics
Venture Round in 2017
EPIX Therapeutics, Inc. is a medical device company based in Santa Clara, California, specializing in the development of advanced temperature-sensing irrigated radiofrequency ablation catheters for the treatment of atrial fibrillation and other cardiac arrhythmias. Utilizing its proprietary TempaSure technology, which incorporates microwave radiometry, EPIX Therapeutics provides precise real-time feedback on volumetric temperature during ablation procedures. This technology enables physicians to control and predict lesion formation more accurately, ultimately enhancing clinical outcomes for patients. Founded in 2007 and previously known as Advanced Cardiac Therapeutics, EPIX Therapeutics has formed strategic partnerships with industry leaders such as Abbott Laboratories and Hansen Medical Inc. The company operates as a subsidiary of Medtronic plc, focusing on improving the treatment of irregular heart rhythms through its innovative catheter-based systems.
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