Ajax Health

XII Medical is a medical device developer focused on addressing obstructive sleep apnea through innovative technology. The company specializes in creating a minimally invasive outpatient solution that utilizes an implantable neurostimulation device. This device functions by preventing the muscles in the throat from relaxing during sleep, thereby avoiding airway blockage. By enhancing oropharyngeal airflow, XII Medical aims to provide patients with a proactive approach to managing their sleep apnea, improving their overall quality of life.

Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.

AcuityMD specializes in developing a software platform for medical device manufacturers. This platform leverages data to enhance device performance and expand market access. It facilitates strategic collaborations between device companies and healthcare providers, fostering closer relationships and improving patient care.

XII Medical is a medical device developer focused on addressing obstructive sleep apnea through innovative technology. The company specializes in creating a minimally invasive outpatient solution that utilizes an implantable neurostimulation device. This device functions by preventing the muscles in the throat from relaxing during sleep, thereby avoiding airway blockage. By enhancing oropharyngeal airflow, XII Medical aims to provide patients with a proactive approach to managing their sleep apnea, improving their overall quality of life.

Third Harmonic Bio is a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for severe allergies and inflammation. The company is focused on advancing its lead product candidate, THB001, which is a first-in-class, highly selective oral inhibitor of the KIT receptor, a key regulator of mast cell function and survival. Mast cells play a crucial role in mediating inflammation in allergic diseases, making this targeted approach significant for treatment. Additionally, Third Harmonic Bio is developing THB335, another potent and selective oral small-molecule KIT inhibitor aimed at addressing various mast cell-driven inflammatory conditions affecting the skin, airway, and gastrointestinal tract. Through its research and development efforts, Third Harmonic Bio seeks to provide new options for patients suffering from inflammatory diseases.

AcuityMD specializes in developing a software platform for medical device manufacturers. This platform leverages data to enhance device performance and expand market access. It facilitates strategic collaborations between device companies and healthcare providers, fostering closer relationships and improving patient care.

Treeline Biosciences is a biotechnology company founded in 2021 and based in Stamford, Connecticut. It focuses on developing transformative precision medicines aimed at treating cancer and other serious health conditions. The company employs a comprehensive drug discovery platform that integrates mechanistic biology, medicinal chemistry, computational science, structural biology, and protein science. This multidisciplinary approach is designed to support the development of innovative therapies that can significantly improve patient outcomes in oncology and beyond.

Atriomx is a medical technology company focused on improving the diagnosis and treatment of cardiac arrhythmias, particularly atrial fibrillation. The company develops non-invasive clinical hardware that utilizes advanced data science to provide deep electrophysiology insights. By employing proprietary algorithms, Atriomx enables healthcare providers to gain a comprehensive understanding of a patient's disease state, facilitating informed decision-making regarding treatment options. This approach aims to enhance patient outcomes while reducing the need for costly and invasive procedures. Through its innovative solutions, Atriomx seeks to transform the management of cardiac conditions by delivering critical information to both doctors and patients.

Protaryx Medical Inc. is a medical device company focused on developing innovative transseptal access devices for minimally invasive cardiac procedures. Founded in 2019 and headquartered in Baltimore, Maryland, with engineering operations in Minneapolis, Minnesota, the company aims to enhance access to the left atrium for transcatheter interventions. Protaryx's devices are designed to facilitate precise and rapid crossing of the septum, enabling surgeons to perform catheter-based interventions with greater reliability and efficiency. By improving access for both physicians and patients, Protaryx is dedicated to advancing the field of cardiac care.

Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.

Verix Health is a medical device company focused on creating a range of actively steerable surgical instruments designed for minimally invasive diagnosis and treatment of challenging lesions in hard-to-reach areas of the human body. Founded by Professor Mark Yim, PhD, in collaboration with PCI Ventures at the University of Pennsylvania, the company is incubated at the Pennovation Center in Philadelphia. Verix Health's innovative devices aim to enhance access and control during surgical procedures, allowing for precise targeting of tumors that are difficult to reach, thereby facilitating minimally invasive treatment options for patients with unfavorable tumor locations.

EPMap-System is a company with over 20 years of expertise in the field of electrophysiology, specifically focusing on heart diagnosis technologies. The company's flagship product, EPPerfect, is a fully integrated solution designed for recording, stimulation, navigation, and ablation procedures in cardiac care. This system enhances the capabilities of hospitals by providing a comprehensive 3D mapping and navigation system that includes integrated signal recording, pacing features, a radiofrequency ablation generator, and an irrigation pump. EPPerfect also supports integration with other solutions, allowing healthcare providers to deliver high-density mapping and precise anatomical tagging, ultimately improving patient care in electrophysiology procedures.

Ablacon Inc., established in 2015 and headquartered in Wheat Ridge, Colorado, specializes in manufacturing advanced machine intelligence systems designed to comprehend and manage atrial fibrillation (AF). The company's core product quantitatively locates and characterizes AF sources, enabling targeted therapy through real-time visualization of electrographic flow within the heart.

EPIX Therapeutics, Inc. is a medical device company focused on developing innovative temperature-sensing irrigated radiofrequency ablation catheters for treating atrial fibrillation and other cardiac arrhythmias. The company utilizes its proprietary TempaSure technology, which employs microwave radiometry to provide real-time assessment of temperature within the heart, allowing physicians to accurately control lesion formation and enhance clinical outcomes. Founded in 2007 and headquartered in Santa Clara, California, EPIX Therapeutics was previously known as Advanced Cardiac Therapeutics, Inc. and rebranded in August 2018. The company has established strategic partnerships with industry leaders, including Abbott Laboratories and Hansen Medical Inc., to further advance its catheter-based systems aimed at improving the management of irregular heart rhythms. EPIX Therapeutics operates as a subsidiary of Medtronic plc.