Amboy Street Ventures

Gesynta Pharma AB is a clinical-stage pharmaceutical company based in Stockholm, Sweden, founded in 2017. The company focuses on developing compounds that inhibit the pro-inflammatory enzyme microsomal prostaglandin E synthase-1 (mPGES-1) to address chronic inflammatory conditions, particularly in cardiovascular diseases and cancer. Its most advanced drug candidate, vipoglanstat (GS-248), is being developed as a non-hormonal treatment for endometriosis, a painful condition affecting around 10 percent of women of reproductive age. Clinical studies have indicated that vipoglanstat significantly reduces endometriotic lesions and provides pain relief, with preparations underway for a phase II clinical trial. Additionally, Gesynta Pharma is advancing another candidate, GS-073, which is set to enter phase I clinical trials for a different inflammatory condition. The company's research is rooted in work from the Karolinska Institutet, and it aims to deliver safe and effective treatments for serious diseases.

Granata Bio is a biotechnology company established in 2018 that specializes in identifying and developing therapeutics for fertility patients. The company focuses on creating a comprehensive portfolio of fertility-related treatments and leverages its expertise in commercialization, late-stage clinical trials, and regulatory development. Granata Bio aims to address significant challenges faced by medical professionals in fertility treatment. Recently, the company announced a partnership with IBSA Institut Biochimique to co-develop a novel subcutaneous progesterone solution, further enhancing its commitment to improving fertility care.

Alloy is a telehealth company focused on addressing the healthcare needs of women over 40. It develops a range of women's health care products designed to promote wellness and effectively manage menopause. The company's offerings include natural solutions aimed at alleviating conditions associated with menopause, osteoporosis, and weight gain. Through its products, Alloy seeks to empower women to lead healthy and fulfilling lives as they navigate the challenges of aging.

Testmate Health is a medtech startup and an award-winning spin-off from the University of Geneva, Switzerland. The company has developed a smartphone-compatible platform that offers a test kit capable of diagnosing diseases with identifiable DNA or RNA sequences without laboratory involvement, providing rapid results at home in minutes. Their initial product is a user-friendly, all-in-one kit that serves as the first rapid urine self-test for the four most common sexually transmitted diseases (STDs). Given that one million new STDs are diagnosed daily, Testmate Health addresses a critical gap in the market, as traditional testing often requires lab processing and can take up to a week for results. The kit not only delivers immediate results but also allows users to scan their results with a smartphone, facilitating quick access to treatment if necessary. Additionally, Testmate Health has plans to expand its offerings with test kits for other diseases, empowering individuals to manage their health conveniently from home.

Granata Bio is a biotechnology company established in 2018 that specializes in identifying and developing therapeutics for fertility patients. The company focuses on creating a comprehensive portfolio of fertility-related treatments and leverages its expertise in commercialization, late-stage clinical trials, and regulatory development. Granata Bio aims to address significant challenges faced by medical professionals in fertility treatment. Recently, the company announced a partnership with IBSA Institut Biochimique to co-develop a novel subcutaneous progesterone solution, further enhancing its commitment to improving fertility care.

Evvy is a company focused on women's health, specializing in at-home vaginal microbiome tests aimed at closing the gender health gap. By utilizing metagenomic sequencing, Evvy's tests analyze individual symptoms and assess risks related to significant health issues. The company provides personalized reports that empower women with insights into their bodies, facilitating a better understanding of their health and promoting overall well-being.

HerMD is a Cincinnati‑based health and wellness company that offers a full range of services for women, including gynecology, menopause care, sexual medicine, obesity counseling, cervical screening, hormone therapy, and medical aesthetics such as facials and chemical peels. Founded in 2019 by Somi Javaid, the company aims to provide a safe, trusted environment for women to address both medical and aesthetic needs.

Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing innovative male birth control solutions. The company is pioneering the first long-lasting, non-hormonal, and reversible contraceptive for men. Its primary product, Echo-V, is an ultrasound-visible polymer solution that is injected into the vas deferens, forming a polymer hydrogel device. This device functions as a semi-permeable membrane, effectively blocking sperm while allowing bodily fluids to pass through. Contraline also offers Vasintomy, a non-surgical procedure for the insertion of Echo-V, providing a cost-effective and accessible approach to male contraception. Incorporated in 2015, Contraline aims to transform the landscape of reproductive health for men.

Hey Jane is a telehealth startup that connects patients to healthcare providers that offer online medical consultations. The company's innovative Complete Care model utilizes technology for unparalleled layers of support: medical, emotional, and social. Since 2021, Hey Jane has helped nearly 20,000 patients get the care they need. And this is only the beginning; soon, we will reimagine care for even more common but underserved treatments, with the ultimate goal of becoming the most trusted healthcare company out there—one that pushes the boundaries of access with convenient, inclusive, and patient-driven care.

Dame Products is a sexual wellness brand focused on creating innovative and well-engineered sex toys specifically designed to enhance intimacy and empower women's sexual experiences. The company prioritizes a consumer-centric approach, engaging in extensive discussions with women and sex therapists to understand a diverse range of sexual needs. This insight informs the design of their products, which include strap-free, non-intrusive vibrators that seamlessly integrate into users' sex lives. By prioritizing functionality and user experience, Dame Products aims to help individuals take control of their sexuality and pleasure.

Aunt Flow Corp. is a manufacturer and supplier of menstrual products, including organic cotton tampons and biodegradable pads, aimed at ensuring access to menstrual hygiene for all. Established in 2018 and based in Columbus, Ohio, the company sells its products to businesses and schools through wholesalers and online retailers, as well as directly to consumers via its e-commerce platform. In addition to menstrual products, Aunt Flow offers a range of branded merchandise, including apparel and accessories. The company is committed to social responsibility, donating a tampon for every tampon purchased online to individuals in need across the United States. Through its initiatives, Aunt Flow seeks to provide free access to menstrual products in public spaces, thereby supporting the health and dignity of menstruators.

Dipsea Inc. is a San Francisco-based company that specializes in creating an online platform for audio stories aimed at women's entertainment and sexual wellness. Founded in 2017, Dipsea combines original content production with technology to deliver immersive and engaging short audio narratives. The subscription-based application offers a diverse range of non-narrative guided stories designed to empower women to explore their sexuality in a comfortable and accessible manner. By providing auditory erotica, Dipsea aims to spark imagination and enhance the listening experience for its users, making it a unique player in the realm of women's audio entertainment.

Dame Products is a sexual wellness brand focused on creating innovative and well-engineered sex toys specifically designed to enhance intimacy and empower women's sexual experiences. The company prioritizes a consumer-centric approach, engaging in extensive discussions with women and sex therapists to understand a diverse range of sexual needs. This insight informs the design of their products, which include strap-free, non-intrusive vibrators that seamlessly integrate into users' sex lives. By prioritizing functionality and user experience, Dame Products aims to help individuals take control of their sexuality and pleasure.

Gennev is a digital health company based in Seattle, Washington, focused on addressing the unique health needs of women, particularly during midlife and menopause. Founded in 2015, Gennev aims to empower women by increasing access to essential information, healthcare providers, and community support for managing hormone-driven symptoms such as hot flashes, insomnia, anxiety, and loss of libido. The company offers an integrated care model that combines personalized treatment plans with telehealth appointments, allowing women to receive comprehensive care and address menopause-related issues effectively. Through its services, Gennev seeks to help women take control of their health during this pivotal stage of life.