Amboy Street Ventures

Gesynta Pharma is a clinical-stage pharmaceutical company developing compounds that inhibit the pro-inflammatory enzyme mPGES-1. Its lead drug candidate, vipoglanstat (GS-248), is in development for endometriosis, a prevalent chronic inflammatory disease affecting women's health. Gesynta Pharma also has another drug candidate, GS-073, ready to enter clinical phase I trials.

Granata Bio is a biotechnology company established in 2018 that specializes in identifying and developing therapeutics for fertility patients. The company focuses on creating a comprehensive portfolio of fertility-related treatments and leverages its expertise in commercialization, late-stage clinical trials, and regulatory development. Granata Bio aims to address significant challenges faced by medical professionals in fertility treatment. Recently, the company announced a partnership with IBSA Institut Biochimique to co-develop a novel subcutaneous progesterone solution, further enhancing its commitment to improving fertility care.

Alloy is a telehealth company focused on addressing the healthcare needs of women over 40. It develops a range of women's health care products designed to promote wellness and effectively manage menopause. The company's offerings include natural solutions aimed at alleviating conditions associated with menopause, osteoporosis, and weight gain. Through its products, Alloy seeks to empower women to lead healthy and fulfilling lives as they navigate the challenges of aging.

Testmate Health is a medtech startup and award-winning spin-off of the University of Geneva in Switzerland. It has developed a smartphone-compatible platform test kit capable of diagnosing diseases based on identifiable DNA or RNA sequences without the need for a laboratory, delivering results in minutes at home. The initial product is a rapid urine self-test for the four most common sexually transmitted infections, designed to be used outside clinical settings and to provide a smartphone-scanable result that supports immediate access to treatment if needed. The platform uses DNA isothermal technology to detect infectious diseases with identifiable DNA, enabling home testing without laboratory submission. Further test kits for additional diseases are in development to empower users to monitor their health from home.

Granata Bio is a biotechnology company established in 2018 that specializes in identifying and developing therapeutics for fertility patients. The company focuses on creating a comprehensive portfolio of fertility-related treatments and leverages its expertise in commercialization, late-stage clinical trials, and regulatory development. Granata Bio aims to address significant challenges faced by medical professionals in fertility treatment. Recently, the company announced a partnership with IBSA Institut Biochimique to co-develop a novel subcutaneous progesterone solution, further enhancing its commitment to improving fertility care.

Evvy is a company focused on women's health, specializing in at-home vaginal microbiome tests aimed at closing the gender health gap. By utilizing metagenomic sequencing, Evvy's tests analyze individual symptoms and assess risks related to significant health issues. The company provides personalized reports that empower women with insights into their bodies, facilitating a better understanding of their health and promoting overall well-being.

HerMD is a Cincinnati‑based health and wellness company that offers a full range of services for women, including gynecology, menopause care, sexual medicine, obesity counseling, cervical screening, hormone therapy, and medical aesthetics such as facials and chemical peels. Founded in 2019 by Somi Javaid, the company aims to provide a safe, trusted environment for women to address both medical and aesthetic needs.

Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing innovative male birth control solutions. The company is pioneering the first long-lasting, non-hormonal, and reversible contraceptive for men. Its primary product, Echo-V, is an ultrasound-visible polymer solution that is injected into the vas deferens, forming a polymer hydrogel device. This device functions as a semi-permeable membrane, effectively blocking sperm while allowing bodily fluids to pass through. Contraline also offers Vasintomy, a non-surgical procedure for the insertion of Echo-V, providing a cost-effective and accessible approach to male contraception. Incorporated in 2015, Contraline aims to transform the landscape of reproductive health for men.

Hey Jane is a telehealth startup that connects patients to healthcare providers that offer online medical consultations. The company's innovative Complete Care model utilizes technology for unparalleled layers of support: medical, emotional, and social. Since 2021, Hey Jane has helped nearly 20,000 patients get the care they need. And this is only the beginning; soon, we will reimagine care for even more common but underserved treatments, with the ultimate goal of becoming the most trusted healthcare company out there—one that pushes the boundaries of access with convenient, inclusive, and patient-driven care.

Dame Products is a sexual wellness brand dedicated to designing high-quality sex toys that enhance intimacy. The company prioritizes consumer needs, collaborating with women and sex therapists to create vibrators tailored to diverse sexual experiences.

Aunt Flow Corp. is a manufacturer and supplier of menstrual products, including organic cotton tampons and biodegradable pads, aimed at ensuring access to menstrual hygiene for all. Established in 2018 and based in Columbus, Ohio, the company sells its products to businesses and schools through wholesalers and online retailers, as well as directly to consumers via its e-commerce platform. In addition to menstrual products, Aunt Flow offers a range of branded merchandise, including apparel and accessories. The company is committed to social responsibility, donating a tampon for every tampon purchased online to individuals in need across the United States. Through its initiatives, Aunt Flow seeks to provide free access to menstrual products in public spaces, thereby supporting the health and dignity of menstruators.

Founded in San Francisco in 2018, Dipsea is a unique platform offering original, immersive audio stories designed to empower women by providing accessible and engaging content for sexual wellness.

Dame Products is a sexual wellness brand dedicated to designing high-quality sex toys that enhance intimacy. The company prioritizes consumer needs, collaborating with women and sex therapists to create vibrators tailored to diverse sexual experiences.

Gennev is a digital health company based in Seattle, Washington, focused on addressing the unique health needs of women, particularly during midlife and menopause. Founded in 2015, Gennev aims to empower women by increasing access to essential information, healthcare providers, and community support for managing hormone-driven symptoms such as hot flashes, insomnia, anxiety, and loss of libido. The company offers an integrated care model that combines personalized treatment plans with telehealth appointments, allowing women to receive comprehensive care and address menopause-related issues effectively. Through its services, Gennev seeks to help women take control of their health during this pivotal stage of life.