Ann Arbor SPARK

SecuritySnares specializes in providing solutions to combat malware-related business disruptions. Its primary offering, RansomSnare, is an innovative tool designed to detect and prevent ransomware attacks by halting malicious encryption before any files are compromised. This lightweight micro-agent operates silently on endpoints and can function without signatures, learning periods, or updates, making it suitable for offline use and compatible with older operating systems often found in industrial and healthcare settings. In addition to RansomSnare, the company offers WiperSnare, which addresses the emerging threat of wipers—malware that corrupts or erases files irreversibly. SecuritySnares' products are engineered to complement existing security measures, providing immediate protection against sophisticated cyber threats.

360ofme is a cloud-based personal data exchange platform that enables consumers to manage their digital identities across various sectors, including healthcare, finance, insurance, and automotive. The platform allows users to securely share essential data with chosen family members and professionals, enhancing control over their digital footprint. By leveraging cognitive computing technology, 360ofme provides valuable insights into individual lives, facilitating informed decision-making. The service emphasizes identity assurance and consent management, allowing users to maintain ownership of their personal information while also enabling the monetization of their data in interactions with businesses. This innovative approach supports consumers in navigating the complexities of data management in an increasingly digital world.

GM&T Engineering specialises in the research and development, engineering, and testing of Electrical Distribution Systems (EDS) for the automotive, aerospace, and appliance industries.

Flightpath Biosciences is a biotechnology company based in Berkeley, California, founded in 2019. It specializes in developing innovative therapies aimed at treating rare infectious diseases, particularly those caused by pathogenic bacteria. The company's focus includes antibiotic therapies that target co-infectious bacteria in conditions such as Lyme disease, aiming to reduce microbiome damage and address multiple pathogenic bacteria in both the oral and gut microbiomes. By collaborating with leading scientists and experts in therapeutics and diagnostics across various academic institutions and government agencies, Flightpath Biosciences is committed to exploring diverse fields of biology to create novel and targeted treatment solutions.

Loansense is a debt management platform designed to assist borrowers in reducing their student loan debt and achieving homeownership. The company provides tools for setting financial goals and personalizing debt repayment plans, which help improve borrowers' debt-to-income ratios. By collaborating with networks in mortgage technology and mortgage brokerages, Loansense facilitates quicker mortgage closings for student loan debtors. The platform offers comprehensive financial planning, student loan servicing, and advisory services, enabling users to navigate the complexities of debt management and transition smoothly into homeownership.

Asalyxa Bio, Inc. is a drug development company based in Southfield, Michigan, specializing in novel therapeutics aimed at addressing significant unmet medical needs resulting from the dysregulation of immune signaling. The company has developed a platform technology that facilitates the targeted delivery of both existing and innovative drugs directly into over-reactive immune cells. This approach is particularly focused on combating severe neutrophil-mediated diseases, including conditions such as Covid-19, and has applications across a broad range of disease areas. By leveraging this technology, Asalyxa Bio aims to enhance treatment options and improve patient outcomes in various therapeutic contexts.

Orbion Space Technology, based in Houghton, Michigan, specializes in the development and manufacture of plasma propulsion systems for small satellites. Founded in 2016, the company provides advanced electric propulsion technology that enhances satellite functionality by enabling precise maneuverability in space. Orbion's thrusters facilitate essential tasks such as the last-mile delivery of spacecraft from launch vehicles to their designated orbits, extending the operational life of satellites, and ensuring safe de-orbiting at the end of their missions. By offering a cost-effective solution that can significantly reduce operational expenses for spacecraft operators, Orbion contributes to the growing demand for efficient propulsion systems in the rapidly evolving space industry.

Barracuda Networks is a cybersecurity company that specializes in designing and developing solutions for email and web security. Founded in 2002 and headquartered in Campbell, California, with additional offices globally, the company provides a range of products aimed at protecting organizations from various security threats. Its offerings include the Barracuda Spam Firewall, which safeguards email servers from spam and malicious attacks, and the Barracuda Web Filter, which enforces internet usage policies. Other key products include the Barracuda Message Archiver for email archiving, the Barracuda Load Balancer for server management, and the Barracuda Backup Service for data backup and disaster recovery. Barracuda Networks serves a diverse clientele across industries such as education, government, healthcare, and finance, distributing its products through a network of distributors both domestically and internationally. The company’s solutions are designed to provide comprehensive protection against spam, spyware, viruses, and other IT infrastructure threats, enabling organizations to enhance their network performance and safeguard their data.

SPLT is an enterprise-first carpooling and car sharing platform that connects employees within organizations to share their commute, saving time and money while reducing traffic congestion and lowering CO2 emissions.

Banza LLC is a food manufacturer based in Detroit, Michigan, that specializes in producing and wholesaling chickpea pasta. Founded in 2014, the company offers a variety of pasta shapes, including penne, rotini, shells, and elbows, aimed at providing nutritious comfort food alternatives. Banza's products are designed to be high in protein and fiber, allowing consumers to enjoy their favorite meals without compromising on health. The pasta is available in approximately 8,000 retail locations across the United States, including major stores such as Target, Kroger, and Whole Foods. Banza has received notable recognition, being featured in prominent publications like The New York Times and Bon Appetit, and has been celebrated as one of TIME Magazine's 25 Best Inventions of the Year.

TurtleCell is a mobile accessories company that specializes in innovative protective cases for popular smartphones. Its flagship product features a unique design that incorporates retractable earbuds stored within the case, allowing users to keep their headphones secure and untangled while providing essential protection for their devices. This proprietary mechanism enables the storage of a full-length headphone cord within a case that is thinner than typical external battery cases, offering both functionality and style. TurtleCell aims to address common issues faced by smartphone users, such as losing or damaging their headphones, while delivering an effective and aesthetically pleasing solution.

Argo Labs' team has designed and developed on the web for small businesses with one employee and large corporations with thousands, learning a lot of do’s and dont’s along the way. The company builds sites from the ground up, shot videos for local businesses and families and designed entire online brands. Not to mention we have a perfect track record of meeting each of them one on one to make whatever they need 100% unique. The company combines backgrounds in computer science, engineering, videography, graphic design, marketing, and entrepreneurship. Everyone at Argo Labs has owned or worked for small businesses and has done freelance work on their own.

SkySpecs, Inc. is a technology company based in Ann Arbor, Michigan, with an additional office in Amsterdam, Netherlands, that specializes in automating operations and maintenance for the wind energy industry through unmanned aerial vehicles. Founded in 2012, the company provides a range of services including analytics, wind turbine blade services, and engineering projects. Its offerings also encompass collaborative software solutions for managing and analyzing data from various sources, as well as digitization and planning for repair campaigns. Notably, SkySpecs has developed Horizon, a reporting software that serves as a central repository for operations and maintenance data related to wind turbine blades, facilitating task management, communication with third parties, and execution of large-scale repair projects. By leveraging its industry expertise and innovative technologies, SkySpecs aims to enhance productivity and efficiency for its clients within the renewable energy sector.

CureLauncher, LLC is a healthcare company based in Bloomfield Hills, Michigan, that specializes in clinical trial matching services. Established in 2012, the company connects patients with new treatment options tailored to their specific health conditions and personal goals. In addition to assisting patients, CureLauncher also supports caregivers and healthcare professionals in navigating available clinical trials. Through its online platform, CureLauncher aims to simplify the process of finding suitable medical treatments, ultimately helping users maintain their health and well-being.

Axonia Medical's proprietary approach is to repair and restore damaged peripheral or central nervous systems using tissue-engineered nerve grafts. They are expected to bridge lost nervous tissue and jump-start regenerative mechanisms to achieve levels of functional recovery not possible with current technologies.

Algal Scientific Corporation, founded in 2009 and based in Plymouth, Michigan, specializes in developing and selling algae-based products and technologies for the animal health, human nutrition, and wastewater treatment industries. The company produces Algamune, a beta glucan derived from algae, which enhances the immune health of various livestock and aquatic species, and AlgaGLUCAN, a similar product aimed at human nutraceuticals and functional foods. Additionally, Algal Scientific offers the Hypertrophic wastewater treatment system, designed for the food and beverage sector, which effectively treats dissolved organics, nitrogen, and phosphorus while generating a natural fertilizer co-product. With a focus on sustainable practices, Algal Scientific serves both domestic and international markets, contributing to advancements in health and environmental conservation.

TM3 Systems develops smart, mobile microgrid products for remote and off-grid power applications.

TM3 Systems develops smart, mobile microgrid products for remote and off-grid power applications.

Seelio is an online platform that allows college students to create and showcase digital portfolios to potential employers. Founded in 2011 and based in Ann Arbor, Michigan, it focuses on providing custom portfolio networks and galleries tailored for engineering, design, and business programs. This platform empowers students to document their learning experiences and display their projects effectively. Seelio has partnered with several prominent educational institutions, including the Massachusetts Institute of Technology, the University of Michigan, and the University of Texas at Austin, enhancing the visibility of students' work to recruiters and industry professionals. The company has received venture backing and has gained recognition in notable publications such as Forbes and TechCrunch.

AutoBike, Inc. is a manufacturer of bicycles based in Troy, Michigan, founded in 2011. The company has developed a unique automatic shifting technology aimed at enhancing the cycling experience by making it simpler, more comfortable, and enjoyable. This technology is integrated into AutoBike's own line of bicycles and is also offered to other original equipment manufacturers (OEMs) for inclusion in their products.

Eloquence Communications is a healthcare IT company focused on enhancing care delivery through innovative communication solutions. The company develops nurse-call systems utilizing its proprietary communication technology, Eloquence, which facilitates bi-directional remote communication between patients and their care providers. Eloquence Communications offers two main products: the Advanced Communication System (ACS) and the Language Access Solution (LAS), both designed to enable quick and accurate exchanges between patients and the most qualified providers. By addressing language barriers and improving communication in healthcare settings, Eloquence Communications aims to optimize staffing allocation, enhance workflow efficiency, and ultimately improve patient care outcomes.

Quikly Inc., based in Detroit, Michigan, operates a marketing platform designed to assist consumer brands in executing targeted campaigns that reward both new and existing customers. Founded in 2012, Quikly provides a range of marketing solutions, including email, social, mobile, loyalty, and local marketing, aimed at enhancing customer engagement and driving key behaviors such as purchases and store visits. By leveraging insights from consumer psychology, Quikly’s technology enables brands to boost digital activation and engagement effectively, leading to improved return on investment. The platform is particularly beneficial for digital marketers in sectors such as retail, dining, and consumer-packaged goods, facilitating customer acquisition, activation, and retention through innovative strategies that emphasize scarcity, anticipation, and competition.

AlertWatch, LLC is a clinical decision support system provider based in Ann Arbor, Michigan, established in 2011 as a spinoff from the University of Michigan Health System. The company develops software products, specifically AlertWatch:OR and AlertWatch:ICU, designed to enhance patient monitoring in operating rooms and intensive care units. These systems aggregate data from various sources, including physiological monitors, anesthesia records, lab results, and medical histories, to present a real-time overview of a patient’s condition using a color-coded system to indicate normal, marginal, or abnormal states. AlertWatch:ICU functions as a secondary patient monitor and provides additional features like data trends, SOFA and SIRS scores, alerts specific to ICU settings, and nursing reminders. The company's products are currently implemented at the University of Michigan and several other training hospitals across the United States.

Beet, Inc. specializes in providing diagnostic and analytical tools designed to enhance problem-solving capabilities for operations facing complex assembly and automation challenges. Founded in 2011 and headquartered in Plymouth, Michigan, with an additional office in China, the company offers a range of software solutions under its ENVISION brand. This includes ENVISION Enterprise SMART, ENVISION Sentinel SMART, and ENVISION System Scope, which cater to various operational scales and needs. Additionally, Beet provides a cloud-based Software-as-a-Service solution and consulting services. Its Process Visibility System (PVS) transforms manufacturing workflows by promoting proactive management and predictive maintenance, ultimately maximizing existing asset capacity and reducing unplanned downtime. The company's technology plays a crucial role in advancing manufacturers' efforts towards Industrial IoT and Industry 4.0, positioning them to improve production efficiency through real-time data utilization. Beet serves a diverse clientele, including automotive original equipment manufacturers and tooling manufacturers.

Advanced Battery Concepts, LLC is a company specializing in the design and development of bi-polar lead acid batteries. Founded in 2008 and based in Clare, Michigan, it aims to enhance battery performance across various sectors, including military, industrial, stationary, renewable, automotive, and motive markets. The company focuses on advancing battery electrode technologies to address the challenges associated with bipolar batteries. Its innovative products offer uniform current density, increased active material utilization, and improved energy and power density, which contribute to enhanced performance at lower production costs compared to conventional lead-acid batteries. Advanced Battery Concepts was previously known as Advanced Battery Concepts Michigan before rebranding in March 2011.

3D Biomatrix Inc. specializes in designing and manufacturing three-dimensional cell culture plates and scaffolds, specifically tailored for cellular assays in drug discovery. Founded in 2010 and located in Ann Arbor, Michigan, the company offers its products in 96- and 384-well plate formats, enhancing the ability of researchers to conduct sophisticated experiments. The scaffolds developed by 3D Biomatrix are utilized in various applications, including bone marrow, hepatocytes, and thymus, aiding researchers and drug discovery professionals in their efforts to treat cancer and tumors.

Fusion Coolant Systems, Inc. specializes in manufacturing and marketing advanced coolant and lubrication systems for various manufacturing industries. The company offers products such as Pure-Cut 1000 and LUBE-CUT 1600, which utilize supercritical carbon dioxide for dry lubrication and efficient cooling during cutting processes. These systems are designed to enhance production rates and extend tool life while addressing the limitations of traditional metalworking fluids, which often contain harmful chemicals and contribute to environmental pollution. Fusion Coolant's patented CHiP Lube system represents a significant advancement in metalworking technologies, improving operational efficiency and promoting worker safety. The company serves diverse sectors, including medical, aerospace, automotive, and power generation, and also provides infrastructure solutions like carbon dioxide storage tanks and pumps. Founded in 2009 and headquartered in Canton, Michigan, with an office in Saint-Priest, France, Fusion Coolant has established a strategic partnership with Air Liquide to further its innovations in coolant technology.

Larky, Inc. is a marketing and engagement platform that specializes in connecting organizations with their audiences through targeted geo-notifications and relevant communications. The company offers two main products: a nudge mobile platform, which facilitates audience engagement via location-based notifications, and Larky Classic, a mobile engagement solution designed to enhance communication with members, support local businesses, and foster loyalty. Additionally, Larky provides a merchant-funded loyalty platform that enables users to receive instant savings at local merchants. Larky serves a diverse client base, including financial institutions, health insurance providers, universities, and media companies across the United States and Canada. Founded in 2011 and headquartered in Ann Arbor, Michigan, Larky was previously known as PerkPerk, Inc.

Algal Scientific Corporation, founded in 2009 and based in Plymouth, Michigan, specializes in developing and selling algae-based products and technologies for the animal health, human nutrition, and wastewater treatment industries. The company produces Algamune, a beta glucan derived from algae, which enhances the immune health of various livestock and aquatic species, and AlgaGLUCAN, a similar product aimed at human nutraceuticals and functional foods. Additionally, Algal Scientific offers the Hypertrophic wastewater treatment system, designed for the food and beverage sector, which effectively treats dissolved organics, nitrogen, and phosphorus while generating a natural fertilizer co-product. With a focus on sustainable practices, Algal Scientific serves both domestic and international markets, contributing to advancements in health and environmental conservation.

Local Orbit is a business management tool provider that focuses on enhancing the food system within the connected food economy. The company has developed an elegant platform that facilitates multi-channel sales, streamlined purchasing, and efficient business management for various stakeholders in the food supply chain. This includes farmers, food producers, chefs, and independent distributors. By addressing the challenges of disconnected markets and inefficient communication, Local Orbit supports entrepreneurs and local producers in building effective relationships with wholesale buyers, thereby enabling the development of emerging supply chains.

Envy Modular Wall Systems specializes in the manufacturing and installation of lightweight modular panels designed for temporary construction barriers. Founded by Doug Spear, the company emerged from extensive experience in construction and business, addressing the need for a versatile wall system that meets the demands of various industries. The panels are easy to assemble and disassemble, utilizing 100% recycled materials, which makes them reusable after dismantling and fully recyclable thereafter. This innovative approach allows service companies in sectors such as industrial construction, airports, casinos, malls, and stadiums to expedite project timelines while maintaining environmental sustainability.

Mitostem, Inc. was founded in 2008 with the goal to drive innovation, and accelerate the scientific breakthroughs that will advance Stem Cell research and the field of Regenerative Medicine. MitoStem focuses on developing and commercializing novel technologies to advance stem cell research and the field of regenerative medicine. Stem cells have the ability to reproduce themselves (self-renew) or differentiate into each of the cell types found in the body. In the future, Pluripotent Stem Cells (PSC) will be able to replace diseased and damaged organs. Until recently, only stem cells derived from embryos were pluripotent. However, controversies are associated with using cells from embryos, and they can only be used for study of diseases that are diagnosed during assisted reproduction procedures (in vitro fertilization).

Millendo Therapeutics is a biopharmaceutical company dedicated to developing innovative treatments for endocrine diseases resulting from hormone dysregulation. The company focuses on creating distinct and transformative therapies that address significant unmet medical needs in this area. By leveraging scientific advancements, Millendo aims to develop novel compounds that can effectively treat complex conditions, ultimately enhancing clinical care and improving the quality of life for patients, families, and caregivers.

FreeStride Therapeutics, Inc. specializes in developing innovative therapies for companion animals, with a focus on treating conditions such as arthritis and lameness. The company aims to go beyond mere pain relief by addressing the underlying mechanisms that promote healing in horses, dogs, and cats. FreeStride is committed to creating safe and effective treatments that enhance the quality of life for pets, allowing them to lead active lifestyles. The management team brings extensive expertise from biotechnology, research, and drug development, ensuring a strong foundation for their initiatives. Additionally, FreeStride's healthcare platform offers therapeutic services targeting inflammation and bone loss, providing veterinary practitioners with high-quality products to improve animal health outcomes.

Seelio is an online platform that allows college students to create and showcase digital portfolios to potential employers. Founded in 2011 and based in Ann Arbor, Michigan, it focuses on providing custom portfolio networks and galleries tailored for engineering, design, and business programs. This platform empowers students to document their learning experiences and display their projects effectively. Seelio has partnered with several prominent educational institutions, including the Massachusetts Institute of Technology, the University of Michigan, and the University of Texas at Austin, enhancing the visibility of students' work to recruiters and industry professionals. The company has received venture backing and has gained recognition in notable publications such as Forbes and TechCrunch.

Axonia Medical's proprietary approach is to repair and restore damaged peripheral or central nervous systems using tissue-engineered nerve grafts. They are expected to bridge lost nervous tissue and jump-start regenerative mechanisms to achieve levels of functional recovery not possible with current technologies.

Celsee Diagnostics (formerly DeNovo Sciences) mission is to provide an easy to use platform for cancer research and diagnosis. Specifically, the company will sell an instrument system and reagent kit that allows for the separation, detection, and retrieval of circulating tumor cells (CTCs) from peripheral whole blood as an alternative to traditionally painful and invasive biopsies. Their company is developing a proprietary product that will not only allow researchers to identify and capture rare and difficult to harvest cancer cells in a microfluidic chip but also enable them to conduct downstream molecular analysis. This technology allows for the development of personalized therapies as well as the ability to monitor patient prognosis.

Oxus is a technology company that designs and manufactures oxygen concentrator products for several markets. Oxus has been in business for over 13 years. Oxus is proud to manufacture the Oxus Portable Oxygen Concentrator in the USA.

Blaze Medical Devices, LLC, founded in 2006 and based in Ann Arbor, Michigan, specializes in developing biomedical equipment for assessing the properties of stored blood, particularly focusing on red blood cells. The company offers advanced technologies, including the RBC Mechanical Fragilimeter™ and RBC Hemolysis Tester systems, which measure the mechanical fragility of red blood cells. These products cater to a range of industrial research and development needs, as well as future medical applications. By providing standardized assessments of blood cell damage, Blaze Medical Devices supports product developers and clinical researchers in understanding and mitigating quality loss during blood storage.

First Sense Medical specializes in developing non-invasive medical devices aimed at enhancing breast cancer screening. The company's primary product, the Breast Exam, utilizes advanced thermal profiling technology to detect abnormal heat patterns in breast tissue. This non-invasive test identifies physiological changes that may indicate an increased risk of breast cancer, providing healthcare professionals with valuable information for risk assessment in women of all ages. The Breast Exam system integrates patient biopsy data, compares it against national databases, and continuously updates its algorithms to improve accuracy and effectiveness, ensuring that the device remains at the forefront of medical technology in the fight against breast cancer.

FlockTAG operates a universal loyalty card network aimed at supporting independent neighborhood businesses by enhancing customer loyalty programs. The company has developed a mobile loyalty system that simplifies the process for businesses to manage their customer engagement initiatives. By partnering with local merchants, FlockTAG enables them to offer meaningful rewards and discounts to customers, fostering a stronger connection between businesses and their clientele. Customers can easily register for a FlockTAG card at participating locations, allowing them to earn points and access exclusive deals at various venues. This initiative not only benefits consumers by providing attractive offers but also helps businesses boost profitability by reducing competitive pricing pressures.

Ventech, LLC specializes in providing mobile heating solutions, primarily through its flagship product, the Liquid Heat Generator (LHG). This innovative system is designed for portable applications, generating heat quickly and efficiently by utilizing proprietary technology. Ventech's product offerings include various components such as vehicle harnesses, control modules, mounting brackets, dashboard switches, and other essential parts tailored for school buses, mass transit, and bus original equipment manufacturers (OEMs). The company serves clients in the transportation sector, including diesel generators, pickup trucks, and emergency vehicles, focusing on reducing fuel consumption, lowering emissions, and enhancing overall comfort and engine longevity. Ventech operates through a network of dealers across the United States and Canada and is headquartered in Wixom, Michigan. Founded in 2003, the company continues to pursue opportunities in transportation and commercial vehicle markets.

Empirical Bioscience, LLC is a company based in Grand Rapids, Michigan, that specializes in designing and manufacturing high-grade molecular biology reagents for various applications in research, education, and diagnostics. The company offers a wide range of PCR reagents optimized for standard, quantitative, and real-time PCR research across human, animal, and plant DNA. Their product lineup includes the rEVAlution qPCR Master Mix, an environmentally friendly hot-start qPCR mixture, and the Taq 2x MeanGreen Master Mix, which provides a ready-to-use solution for efficient PCR amplification. Additionally, Empirical Bioscience supports custom configurations of its products and offers technical assistance for assay and product development. The company, incorporated in 2009, was previously known as Syzygy Biotech Inc. and rebranded in February 2014.

VNN, Inc. operates a prominent high school sports marketing and networking platform that serves as a digital hub for athletes, coaches, and fans. The platform enables athletes to upload videos, photos, stories, and scores, while allowing coaches to report game results to various media outlets. VNN is dedicated to enhancing the experience of high school sports by aggregating the fragmented market and providing advertising and promotional services. The company has established a significant presence, serving schools across multiple states, including Alabama, California, and Texas, and has gained a rapidly growing user base, with over 7 million fans engaging with the platform daily. Founded in 2010 and based in Grand Rapids, Michigan, VNN aims to transform the consumer experience in high school sports by leveraging technology and connectivity.

ePaySelect restructures monthly payments into smaller, more affordable payments that are much less than the customer expects. These automated payments are collected on paydays, held and paid to the lender on the due date. This eliminates late fees and protects credit ratings. Retailers benefit because smaller payments are inherently easier to sell. Customers include retailers like auto dealerships or anyone who needs help making monthly payments

Coliant Corporation specializes in the manufacturing and distribution of rugged electrical devices and accessories designed for powersport environments. The company offers a wide range of products, including powersport connectors, tire inflaters, battery charging solutions, and heated clothing such as jacket liners and gloves. Additionally, Coliant provides various mounting systems, power distribution products, and direct power cables compatible with devices like iPods and GPS units. Their products are designed for use with motorcycles, snowmobiles, all-terrain vehicles, and personal watercraft, and are available through dealers and online in multiple regions, including the United States, Europe, and Asia. Founded in 2001 and based in Warren, Michigan, Coliant serves both individual customers and powersport vehicle manufacturers, positioning itself as a reliable provider in the industry.

Clean Emission Fluids, Inc. manufactures fueling and fluid dispensing solutions for the transportation industry. It also resells biofuels, clean diesel, and emission related fluids. The company’s product enables fleet operators, truck stops, gas stations, and municipal fleets to store and dispense fluids and fuels. Clean Emission Fluids, Inc. was incorporated in 2007 and is based in Grosse Pointe, Michigan.

Ix Innovations is dedicated to enhancing the usability of electrical test and measurement instrumentation.

Estrakon is a fabrication company that specializes in designing and producing electronic signage and custom marketing media using a variety of materials. With advanced facilities in the USA, UK, and China, Estrakon focuses on creating visually appealing products that enhance brand visibility. The company is recognized for its innovative edge-lit display technologies, which are particularly effective in premium brand advertising and consumer displays. Committed to quality, Estrakon employs the latest construction techniques to ensure products are both durable and cost-effective for large-scale production. They prioritize research and development to continuously improve their offerings and maintain a competitive edge. Clear communication between clients and Estrakon's design and production teams is emphasized throughout the project lifecycle to ensure that all specifications are met precisely.

Arbor Plastic Technologies, LLC is a manufacturer and marketer of specialty additives and related delivery systems for the plastic resin industry. Established in 2007 and based in Sterling Heights, Michigan, the company produces a range of products including process enhancer additives, multi-functional pellets, and foaming agents. Its innovative additive delivery system allows for the integration of various additives—such as UV stabilizers, fire retardants, and colorants—into a single pellet, which enhances production efficiency and provides significant value to clients in the additive and plastic industries.

LEID Products, also known as Law Enforcement Intelligent Devices, LLC, specializes in the manufacturing of electronic lockers and cabinets designed to enhance asset security for various organizations, particularly police departments. Their innovative systems utilize electronic tracking and fingerprinting technology to safeguard critical assets such as firearms, radios, and other equipment. Beyond law enforcement, LEID's products have been employed in diverse sectors, including amusement parks for tracking radios, libraries for managing books and media, and businesses for securing sensitive documents. These solutions offer biometric, keypad, and card swipe access, ensuring that valuable assets are both protected and easily monitored.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

Practical EHR Solutions, Pehr for short (pronounced “pear”), is a company that specializes in implementing and supporting electronic health records in physician groups. Pehr's mission is to improve patient outcomes. As healthcare professionals, the Pehr founders understand just how important a physician’s individuality is and have developed a unique and practical electronic health record implementation methodology to preserve that individuality. Pehr focuses on enhancing the physician experience by improving the physician’s work day, increasing the practice’s profitability and improving quality and safety. This results in quick acceptance and full functionality use of the EHR. It is this use of full feature functionality that patient outcomes can, and will, improve.

Empirical Bioscience, LLC is a company based in Grand Rapids, Michigan, that specializes in designing and manufacturing high-grade molecular biology reagents for various applications in research, education, and diagnostics. The company offers a wide range of PCR reagents optimized for standard, quantitative, and real-time PCR research across human, animal, and plant DNA. Their product lineup includes the rEVAlution qPCR Master Mix, an environmentally friendly hot-start qPCR mixture, and the Taq 2x MeanGreen Master Mix, which provides a ready-to-use solution for efficient PCR amplification. Additionally, Empirical Bioscience supports custom configurations of its products and offers technical assistance for assay and product development. The company, incorporated in 2009, was previously known as Syzygy Biotech Inc. and rebranded in February 2014.

ArborWind LLC is a green energy company based in Ann Arbor, Michigan, that specializes in the manufacturing and installation of vertical axis wind turbines. Founded in 2010, ArborWind focuses on providing economical and efficient energy solutions, particularly to rural areas. Its turbines are designed to meet the energy needs of various applications, including agricultural, industrial, commercial, and residential settings. By harnessing wind energy, ArborWind aims to minimize costly expenses, transmission losses, and logistical challenges often associated with traditional energy sources, thereby promoting sustainable energy generation.

Reveal Design Automation, Inc. is a start-up based in Ann Arbor, Michigan, specializing in electronic design automation (EDA) software tools aimed at enhancing the formal verification of intricate semiconductor chip designs. Founded in 2009, the company offers Reveal-AV, a product that employs architectural equivalence methodology to ensure comprehensive design verification of various core types, including CPU, MPU, DSP, GPU, and microcontroller RTL against the instruction set architecture (ISA) specifications. Reveal's automated solutions significantly streamline the verification process, enabling tasks that typically take days with other methods to be completed in hours. This efficiency can lead to substantial cost savings for chip designers, reducing verification expenses and accelerating time-to-market, while also bolstering confidence in the accuracy and reliability of chip designs.

Zipments is a local logistics platform that offers same-day delivery services to businesses and individuals. Customers can request local deliveries through its website, mobile app, or by utilizing an API integrated into various online retailers' shopping carts. The service caters to multiple sectors, including retail, professional services, and restaurants, providing an efficient solution for businesses seeking reliable delivery options. Additionally, Zipments serves consumers who require assistance with personal deliveries, making it a versatile choice for local logistics needs. The platform allows users to track packages and receive instant notifications, enhancing the delivery experience.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

NextCAT specializes in the commercialization of innovative catalysts designed for biodiesel production. Developed at the National Biofuels Energy Lab at Wayne State University, these catalysts enable producers to reduce overall production costs by optimizing feedstock usage and streamlining processing steps, resulting in higher efficiency. The company is backed by a team of experts in catalysis and an experienced management group, positioning it to significantly impact the biodiesel industry. By enhancing production methods, NextCAT aims to support a transition towards more sustainable energy sources, contributing to reduced dependence on foreign oil and a healthier environment.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Fulcrum Composites Inc is a Michigan based company dedicated to developing new products and bringing them to market. Although their product portfolio is diverse, they are linked by common themes of structural efficiency obtained by synergistic and often unconventional combinations of materials and manufacturing processes.

Armune BioScience, Inc. is a medical diagnostics company based in Kalamazoo, Michigan, focused on developing and commercializing blood tests that utilize the immune system's responses to detect cancer early. Founded in 2007 by members of the Apjohn Group, the company specializes in diagnostic and prognostic tests for prostate, lung, and breast cancers, facilitating personalized treatment decisions for patients and physicians. Its flagship product, APIFINY, is a cancer-specific blood test that assesses the risk of prostate cancer by measuring immune-related biological markers, and is utilized by primary care physicians, urologists, and oncologists. Armune BioScience operates through direct sales to healthcare providers and authorized representatives and has secured exclusive licensing of its technology from the University of Michigan, based on significant research published in reputable medical journals. As of December 2023, Armune operates as a subsidiary of Exact Sciences Corporation.

Inventure Enterprises Inc. is a management consulting and technology services firm based in East Lansing, Michigan, founded in 2002. The company specializes in providing a range of performance solutions, including secure background checks, homeland security, human capital management, and customer relationship management. It also offers information technology application services, encompassing application development and modernization, business intelligence, and mobile applications. One of its key products is idView, a comprehensive background check suite that streamlines the background check process from request to final disposition. Inventure Enterprises serves various sectors, including federal and state government, defense, security, manufacturing, financial services, energy, transportation, and healthcare, both domestically and internationally.

Current Motor Company is based in Ann Arbor, Michigan, and specializes in the development and manufacture of electric motor scooters aimed at urban commuters. The company produces all-electric maxi-scooters that are designed to be fast, fun, and affordable, offering zero-emission transportation solutions. These maxi-scooters can reach speeds of up to 70 MPH and have a range of up to 50 miles, charging conveniently from a standard 110V outlet in approximately five hours. Current Motor sells and services its products through a network of dealers and has formed a strategic partnership with Dakkota Integrated Systems. The company is supported by various investors, including BELLE Capital and the State of Michigan.

NextCAT specializes in the commercialization of innovative catalysts designed for biodiesel production. Developed at the National Biofuels Energy Lab at Wayne State University, these catalysts enable producers to reduce overall production costs by optimizing feedstock usage and streamlining processing steps, resulting in higher efficiency. The company is backed by a team of experts in catalysis and an experienced management group, positioning it to significantly impact the biodiesel industry. By enhancing production methods, NextCAT aims to support a transition towards more sustainable energy sources, contributing to reduced dependence on foreign oil and a healthier environment.

InfoReady Corporation is a software development company based in Ann Arbor, Michigan, specializing in web-based solutions for higher education institutions. Founded in 2010, InfoReady offers tools designed to streamline workflow and enhance the grant application process. Its primary products include InfoReady Review, which connects researchers with relevant research grants, and InfoReady Thrive, a marketplace for scholarships, fellowships, and internships. The platform integrates various functions such as form building, document collection, and reporting into a single user-friendly interface, improving productivity and communication among academic teams. With a client base of over 200 institutions worldwide and a client retention rate exceeding 90%, InfoReady is recognized for its commitment to operational efficiency and effective process management, ultimately enhancing transparency and engagement within academic environments.

Sentio MMG® is a surgical access tool. It is intended to locate and map motor nerve roots and their peripheral extensions originating from spinal levels C3-T1 and L2-S2. Sentio MMG® smart-sensors are different from all other forms of neuromonitoring electrodes. In contrast to electromyography, or EMG, which relies on needles to detect subtle changes in electrical signals in muscle, Sentio MMG® smart-sensors employ proprietary accelerometer technology. These non-invasive accelerometer-based sensors measure MMG (mechanomyography) activity, or the mechanical “twitch” associated with muscle contraction. When MMG activity is detected, the surgeon is provided with a ‘STOP’ alert indicating a nerve has been identified. The result is an intuitive, surgeon-directed tool for establishing safe access in a variety of surgical applications. Sentio MMG® was specifically designed to facilitate safe lateral transpsoas surgery. Sentio believed there was a better way to identify and map nerves during lateral surgery that did not require EMG. Design objectives included:

Trapelo Health is a healthcare technology company based in Cambridge, Massachusetts, that specializes in precision oncology. Founded in 2009, it has developed a collaborative decision support platform that provides evidence-based reports in molecular oncology. This platform aids physicians, payers, and laboratories by aligning molecular test results with corresponding therapies based on the latest medical evidence. By facilitating real-time access to crucial information, Trapelo Health supports oncologists in the analysis of cancerous tissues and the generation of genomic profiles, enabling them to identify appropriate treatments and make informed decisions regarding molecular diagnostics and targeted therapeutics. The company also maintains a strategic partnership with Concert Genetics to enhance its services.

Mandy & Pandy teaches kids Chinese in a fun and easy way through books, CDs, DVDs, toys, fashion, and television. Similarly, Mandy & Pandy teaches English to Chinese-speaking children.

RealBio Technology, Inc. is a life science product development company based in Kalamazoo, Michigan, founded in 2009. The company specializes in advanced cell and tissue culture technologies that enhance the growth and differentiation of human and non-human cells. Its flagship product, the Nth Degree System, is a disposable, single-use 3D perfusion bioreactor designed to create in vitro cultures that closely mimic natural in vivo environments. This innovative technology supports researchers in regenerative medicine, in-vitro modeling, and bio-production by allowing for controlled nutrient and gas gradients within the culture chamber. RealBio Technology serves scientists and healthcare professionals by providing tools that facilitate more realistic and effective research outcomes.

Algal Scientific Corporation, founded in 2009 and based in Plymouth, Michigan, specializes in developing and selling algae-based products and technologies for the animal health, human nutrition, and wastewater treatment industries. The company produces Algamune, a beta glucan derived from algae, which enhances the immune health of various livestock and aquatic species, and AlgaGLUCAN, a similar product aimed at human nutraceuticals and functional foods. Additionally, Algal Scientific offers the Hypertrophic wastewater treatment system, designed for the food and beverage sector, which effectively treats dissolved organics, nitrogen, and phosphorus while generating a natural fertilizer co-product. With a focus on sustainable practices, Algal Scientific serves both domestic and international markets, contributing to advancements in health and environmental conservation.

Azenic is a dental device company focusing on unmet market needs in the dental profession with emphasis on novel disposable instruments. Axenic Dental was founded in 2008 and is based in Kalamazoo, Michigan.

Michelle's Miracle, Inc., operating under the name Cherry Works, specializes in the production and sale of dietary supplements derived from Montmorency tart cherry concentrate. Founded in 2001 and based in Traverse City, Michigan, the company offers its products in various forms, including concentrates and tablets, aimed at promoting wellness, exercise recovery, muscle and joint relief, and improved sleep. Its offerings are designed to support healthy joint and cartilage function, immune health, cardiovascular health, cognitive performance, and sleep hygiene. Michelle's Miracle markets its products online and through health food stores and grocery retailers across North America. Additionally, the company engages in private label packaging and is actively seeking partnerships for custom supplement formulations. The company was previously known as Leland Cherry Company, Inc. before rebranding in September 2008.

White Pine Systems, LLC (dba SPINN) is dedicated to delivering a complete solution for consumer-engaged healthcare that compliments existing health information technology investments. Their Internet-based patient engagement systems are at the core of the rapidly emerging “connected health” movement. Connected health uses technology to provide access to critical personal health information, improve communication between healthcare providers, patients and their families, and better manage chronic conditions to facilitate living normal lives.

Epsilon Imaging, Inc. specializes in the design and development of software and algorithms for cardiac ultrasound medical imaging. Based in Ann Arbor, Michigan, the company provides a vendor-neutral suite of applications that enhance workflow in echocardiography, including EchoInsight Pro for larger clinical practices, EchoInsight Stand-alone for smaller programs, and various EchoInsight Applications for managing echocardiography indications. These solutions incorporate innovative visualization and analysis technologies, such as clinical strain imaging, aimed at improving the quality and efficiency of cardiac diagnostics. Epsilon Imaging also offers robust customer support, with a team of technical and clinical specialists who provide training and consultation services to optimize the use of their products. Founded in 2008 and originally known as Ultrasound Medical Devices, Inc., Epsilon Imaging is committed to transforming cardiovascular patient management through streamlined and standardized echocardiography processes.

Base4 Biotechnology is focused on advancing RNA-targeted therapeutics through innovative small molecule modulation aimed at addressing previously untreatable diseases. Utilizing a proprietary structure-based discovery platform, the company integrates advanced computational technologies with experimental validation to explore and unlock the potential of RNA targets. This approach allows Base4 to tackle complex diseases across various therapeutic areas, including neurology, oncology, and rare diseases. By bridging the gap between computational discovery and practical application, Base4 aims to contribute significantly to the development of transformative medicines in the healthcare industry.

OcuSciences is a medical diagnostic device company that specializes in developing a non-invasive ocular imaging technique known as flavoprotein fluorescence (FPF). This innovative technology is designed to assess retinal metabolic activity, allowing for the detection and monitoring of retinal mitochondrial dysfunction and various retinal diseases, including diabetic retinopathy, macular degeneration, and glaucoma. By focusing on the ocular manifestations of diabetes, OcuSciences aims to provide ophthalmologists with a valuable tool to identify early signs of disease through indicators observed in the eye, ultimately enhancing patient care and treatment options.

Arbor Photonics, LLC, located in Ann Arbor, Michigan, specializes in the development of optical-fiber technology, focusing on advanced fiber laser systems. The company is dedicated to creating high-performance laser solutions that combine exceptional beam quality with significant optical power. Its innovations serve various sectors, including laser materials processing and defense applications, positioning Arbor Photonics as a notable player in the fiber laser market.

Biotectix, LLC is a company that specializes in the development and commercialization of bioactive conductive polymer electrodes and coatings for medical devices. Founded in 2007 and based in Richmond, California, Biotectix produces innovative products such as Amplicoat, which optimizes communication between human tissue and medical device electrodes, and Tecticoat, a conductive coating for textiles and materials that provides electrical conductivity and shielding. Their products are utilized in a wide range of medical devices, including retinal and cochlear prostheses, pacemakers, biosensors, and deep brain stimulators. Biotectix primarily serves medical device manufacturers, offering solutions that enhance device stability, minimize foreign body reactions, and improve long-term electrical performance. As of September 2017, Biotectix operates as a subsidiary of Heraeus Medical Components LLC.

Creative Byline, Inc. provides an online service that enables writers and editors to connect according to their interests and qualifications. Its Website brings together editors from various publishers and enables them to indicate their interests, as well as make a direct connection between the writer and interested editors. The company was founded in 2007 and is based in Holland, Michigan.

Armune BioScience, Inc. is a medical diagnostics company based in Kalamazoo, Michigan, focused on developing and commercializing blood tests that utilize the immune system's responses to detect cancer early. Founded in 2007 by members of the Apjohn Group, the company specializes in diagnostic and prognostic tests for prostate, lung, and breast cancers, facilitating personalized treatment decisions for patients and physicians. Its flagship product, APIFINY, is a cancer-specific blood test that assesses the risk of prostate cancer by measuring immune-related biological markers, and is utilized by primary care physicians, urologists, and oncologists. Armune BioScience operates through direct sales to healthcare providers and authorized representatives and has secured exclusive licensing of its technology from the University of Michigan, based on significant research published in reputable medical journals. As of December 2023, Armune operates as a subsidiary of Exact Sciences Corporation.

Fulcrum Composites Inc is a Michigan based company dedicated to developing new products and bringing them to market. Although their product portfolio is diverse, they are linked by common themes of structural efficiency obtained by synergistic and often unconventional combinations of materials and manufacturing processes.

ERT Systems, founded in 2005 by John Ellis, a veteran firefighter and incident commander, and Dennis Carmichael, an IT services entrepreneur, specializes in automated resource tracking systems for emergency responders. The company's technology offers a wireless solution that enables real-time tracking and locating of personnel and equipment during emergency situations. By automating this process, ERT Systems enhances the safety of both first responders and the public, addressing one of the key challenges faced by incident commanders in chaotic environments. The company developed a beta version of its product, which was first deployed at the Macomb College Firefighter Training Facility in 2006, marking the beginning of its commitment to improving emergency response operations through innovative technology.

The 3IS navigation structure is configured specifically for the automotive electronics industry. Linked to the navigation are a multitude of public and private domain industry specific databases. This combination produces the most accurate, comprehensive and relevant search results for technical or commercial data in the global automotive electronics industry.

Aursos, Inc. is a biotechnology company focused on the development of innovative treatments for bone loss. Founded in 2007 and headquartered in Kalamazoo, Michigan, with an additional office in Houghton, Michigan, Aursos is known for its black bear PTH (BB-PTH) 1-34, aimed at preventing and treating osteoporosis, including cases related to chronic immobilization. In addition to its pharmaceutical developments, the company has also created implantable orthobiological technology designed for bone grafting procedures, effectively addressing conditions such as bone voids, non-union fractures, and spinal fusions.

AFID Therapeutics, Inc. specializes in developing chemical and biochemical technologies aimed at the design, discovery, delivery, and development of new pharmaceutical drugs. The company produces a diverse array of compounds, including lactones, esters, hydroxy cyclopentane carboxylic acids, amino acids, and advanced diamines, among others. AFID is also engaged in creating chiral chemical entities that mimic the structural and reactive characteristics of biomolecules, thereby influencing essential life processes. Its extensive screening collections feature various ring systems and functionalities, including piperazines, oxazolines, morpholines, and carbohydrate derivatives. The company leverages the structural complexity of carbohydrates to develop therapeutic interventions across a wide range of diseases, such as bacterial and viral infections, cancer, autoimmune disorders, cardiovascular diseases, diabetes, and neurological conditions like Alzheimer's. Its drug targets encompass a variety of enzymes and cellular components, including kinases, nucleases, and cell membranes. Established in 2003, AFID Therapeutics is located in Lansing, Michigan.

Global Energy Innovations Inc. provides alternate energy services. The Company manufactures fuel cell energy systems. Global Energy Innovations serves customers worldwide.

Emiliem, Inc. is a private biotechnology company based in San Francisco, California, that specializes in the development of novel oncology therapeutics and treatments for inflammatory and metabolic diseases. The company focuses on understanding the molecular mechanisms that influence the effectiveness of therapeutics and the potential for adverse drug reactions. Emiliem is actively engaged in drug discovery and development, with a portfolio that includes EM101, EM370, and EM400, which target various kinases and cell cycle pathways. Additionally, the company is interested in diagnostic markers for rare diseases and employs computational methods to predict patient outcomes, both positive and negative. Founded in 2005, Emiliem aims to advance therapeutic options through its innovative research and development efforts.

Vestaron Corporation specializes in the development, manufacture, and sale of peptide-based biologic crop protection products. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides including Spear-T, Spear-Lep, and Leprotec, which target various pests in vegetables, fruits, and field crops. The company aims to enhance crop safety, efficacy, and sustainability by providing biopesticides that address resistance issues while ensuring safety for workers and the environment. Vestaron has received notable accolades for its innovative solutions, including the Bernard Blum Award and the Green Chemistry Challenge Award, recognizing its commitment to environmental stewardship and effective crop protection.

iTrack LLC is a developer of autonomous navigation and tracking software designed to accurately monitor personnel and vehicles. The company's technology, funded by the Department of Defense, aims to provide solutions for situations where GPS may not be accessible, allowing users to manage operations from a safe distance. iTrack has established a partnership with Royal Oak Industries, an engineering and manufacturing firm based in Michigan, to facilitate the commercialization of its products. As part of this collaboration, iTrack plans to relocate its operations from the Oakland University Business Incubator to the headquarters of Royal Oak Industries in Lake Orion, Michigan. This move, scheduled for early 2010, will provide iTrack with essential office and engineering space, as well as administrative and financial support to enhance its business development efforts.

The Advisory Board Company is a provider of research services aimed at leaders in the healthcare industry, serving over 2,700 hospitals, health systems, universities, and mission-driven organizations in the United States and globally. With a team of more than 900 researchers, experts, and consultants, the company focuses on addressing critical issues faced by its members and delivering insights for optimal performance. Its offerings include personalized digital subscriptions, executive education, decision-support tools, and consulting services, tailored to the unique needs of each institution. The Advisory Board Company helps healthcare organizations navigate complex challenges such as clinical workforce management and turnover through actionable strategies and practical resources.

Compendia Bioscience focuses on leveraging a comprehensive collection of cancer genomic data to enhance patient treatment options. The company specializes in providing genomic data and analytical tools designed for researchers involved in oncology drug discovery. By enabling the validation of biomarker and gene target discoveries, Compendia aims to facilitate the development of more effective cancer diagnostics and treatments.

RazorThreat, Inc. specializes in developing cybersecurity software aimed at protecting organizations from targeted cyber attacks that threaten intellectual capital and personally identifiable information. Founded in 2005 and based in Pontiac, Michigan, the company offers a comprehensive suite of tools, including the Threat Analysis Console (TAC), which manages and remediates network threats from various sources. Key components of TAC include the Inter-domain Communication Engine, which identifies communication violations against security policies, the Threat Intelligence Engine that transforms disparate data into actionable insights, and the Risk Intelligence Engine, which correlates vulnerability data with threat intelligence to create a detailed risk assessment. RazorThreat also provides integration and training services, focusing on personalized defense strategies that leverage existing security investments to enhance network security and respond to both internal and external threats in real time.

Vestaron Corporation specializes in the development, manufacture, and sale of peptide-based biologic crop protection products. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides including Spear-T, Spear-Lep, and Leprotec, which target various pests in vegetables, fruits, and field crops. The company aims to enhance crop safety, efficacy, and sustainability by providing biopesticides that address resistance issues while ensuring safety for workers and the environment. Vestaron has received notable accolades for its innovative solutions, including the Bernard Blum Award and the Green Chemistry Challenge Award, recognizing its commitment to environmental stewardship and effective crop protection.

NRG Dynamix, Inc. is a Michigan-based company specializing in the development of hydraulic hybrid powertrains and advanced hydraulic solutions, including piston accumulators and variable displacement gear pumps. Founded in 2004, the company serves a range of applications such as buses, taxis, commercial transport, and automobiles, and also provides products to the U.S. Department of Defense. NRG Dynamix was formerly known as Hybra-Drive Systems, LLC and has focused on creating energy-efficient technologies for on-highway vehicles, utilizing compressed gas for energy storage. The company has developed and patented several innovations in hydraulic hybrid systems and piston accumulators, positioning itself within the off-highway, marine, alternative fuel, and energy storage markets.

XG Sciences, Inc. is a manufacturer of graphene nanoplatelets, which are advanced carbon nanoparticles derived from graphite. Headquartered in Lansing, Michigan, the company produces xGnP brand graphene nanoplatelets in various thicknesses and diameters for diverse applications across automotive, aerospace, medical, electronics, and energy storage sectors. These nanoplatelets are utilized in polymeric and metallic composites, coatings, and concrete additives, as well as in the formulation of conductive inks and coatings, electrodes, and specialty sheet products. XG Sciences also develops energy storage materials for lithium-ion batteries and provides thermal management solutions, including thermal interface materials. The company serves a global customer base, which includes research organizations, automotive suppliers, and various specialty material companies, and collaborates with partners such as national laboratories and universities. Founded in 2006, XG Sciences enhances product performance through its proprietary manufacturing technology and licensed production capabilities.

Phrixus Pharmaceuticals, Inc. is focused on developing and commercializing pharmaceuticals and therapies for heart failure, particularly in patients with Duchenne muscular dystrophy. The company's primary product, Carmeseal, is designed to treat heart failure by repairing muscle damage. Incorporated in 2006 and based in Ann Arbor, Michigan, Phrixus aims to provide cost-effective and efficient therapeutic solutions that support quick recovery for healthcare institutions and their patients.