Ann Arbor SPARK

SecuritySnares is a technology company focused on protecting organizations from cyberattacks, particularly those caused by ransomware and wipers. Its flagship product, RansomSnare, is designed to detect and halt malicious encryption activities before they can compromise files. This lightweight micro-agent operates seamlessly on endpoints, providing real-time protection without the need for signatures, learning periods, or frequent updates, and it can function offline, making it suitable for older operating systems in environments such as manufacturing and healthcare. In addition, SecuritySnares offers WiperSnare, a solution that targets wipers—malware that corrupts or deletes files—providing organizations with a robust defense against this emerging threat. By integrating its products with existing security tools, SecuritySnares enables customers to safeguard their data effectively and efficiently.

360ofme is a cloud-based platform that empowers consumers to manage their personal data across various aspects of their lives, including healthcare, finance, insurance, automotive, and home services. The platform facilitates data ownership and provides users with the ability to securely share critical information with chosen family members and professionals. By leveraging cognitive computing technology, 360ofme offers insights that help individuals gain greater control over their digital footprints. This innovative approach not only enhances identity assurance and consent management but also allows for the monetization of personal data, enabling a more transparent and efficient interaction between consumers and businesses.

GM&T Engineering specialises in the research and development, engineering, and testing of Electrical Distribution Systems (EDS) for the automotive, aerospace, and appliance industries.

Flightpath Biosciences is a biotechnology company based in Berkeley, California, founded in 2019. It specializes in developing innovative therapies aimed at treating rare infectious diseases, particularly those caused by pathogenic bacteria. The company's focus includes antibiotic therapies that target co-infectious bacteria in conditions such as Lyme disease, aiming to reduce microbiome damage and address multiple pathogenic bacteria in both the oral and gut microbiomes. By collaborating with leading scientists and experts in therapeutics and diagnostics across various academic institutions and government agencies, Flightpath Biosciences is committed to exploring diverse fields of biology to create novel and targeted treatment solutions.

LoanSense is a debt management platform focused on assisting borrowers in reducing student loan debt and facilitating homeownership. The company collaborates with networks in mortgage technology and mortgage brokerages to streamline the mortgage process for student loan debtors. Through its platform, LoanSense offers personalized financial planning by helping users set goals and create tailored plans aimed at improving their debt-to-income ratios. The platform also provides advisory services and monthly payment calculations, empowering borrowers to navigate student loan servicing and expedite mortgage closings effectively.

Asalyxa Bio, Inc. is a drug development and platform technology company based in Southfield, Michigan, focusing on innovative therapeutics to address significant unmet medical needs linked to immune signaling dysregulation. The company specializes in developing neutrophil-targeting drugs aimed at combating severe neutrophil-mediated diseases, including conditions like Covid-19. Asalyxa Bio's platform technology facilitates the targeted delivery of both existing and novel drugs directly into over-reactive immune cells, thereby enhancing treatment efficacy. This approach allows for applications across a diverse range of diseases and conditions, positioning Asalyxa Bio as a key player in the field of immunotherapy.

Orbion Space Technology, Inc., established in 2016 and headquartered in Houghton, Michigan, specializes in developing and manufacturing plasma propulsion systems tailored for small satellites. The company's electric propulsion technology significantly reduces operational costs and enhances the value of satellite data products. Orbion's innovative manufacturing approach enables high-volume production of these thrusters, catering to the growing demand for space revolution applications such as last-mile delivery, on-orbit maneuvering, collision avoidance, and safe de-orbiting at mission end.

Barracuda Networks is a cybersecurity company that specializes in designing and developing solutions for email and web security. Founded in 2002 and headquartered in Campbell, California, with additional offices globally, the company provides a range of products aimed at protecting organizations from various security threats. Its offerings include the Barracuda Spam Firewall, which safeguards email servers from spam and malicious attacks, and the Barracuda Web Filter, which enforces internet usage policies. Other key products include the Barracuda Message Archiver for email archiving, the Barracuda Load Balancer for server management, and the Barracuda Backup Service for data backup and disaster recovery. Barracuda Networks serves a diverse clientele across industries such as education, government, healthcare, and finance, distributing its products through a network of distributors both domestically and internationally. The company’s solutions are designed to provide comprehensive protection against spam, spyware, viruses, and other IT infrastructure threats, enabling organizations to enhance their network performance and safeguard their data.

SPLT is an enterprise-first carpooling and car sharing platform that connects employees within organizations to share their commute, saving time and money while reducing traffic congestion and lowering CO2 emissions.

Banza LLC is a food manufacturer based in Detroit, Michigan, specializing in chickpea-based pasta products. Founded in 2014, the company offers a variety of pasta shapes, including penne, rotini, shells, and elbows, all designed to provide nutritious alternatives to traditional pasta. Banza's mission is to make healthy food more accessible, and its products are enriched with protein and fiber, catering to consumers seeking delicious comfort food without compromising on health. The brand has gained significant recognition, being available in approximately 8,000 retail locations across the United States, including major stores like Target, Kroger, and Whole Foods. Banza has received endorsements from prominent media outlets, highlighting its innovation and contribution to the food industry.

TurtleCell is a mobile accessories company that specializes in innovative protective cases for popular smartphones. Its flagship product features a unique design that incorporates retractable earbuds within the case, allowing users to conveniently store and manage their headphones. This design not only provides protection for the device but also addresses common issues such as tangling and loss of headphones. TurtleCell's cases are engineered to accommodate a full-length cord while maintaining a profile thinner than traditional battery cases, making them both functional and stylish for consumers seeking enhanced mobile accessory solutions.

Argo Labs' team has designed and developed on the web for small businesses with one employee and large corporations with thousands, learning a lot of do’s and dont’s along the way. The company builds sites from the ground up, shot videos for local businesses and families and designed entire online brands. Not to mention we have a perfect track record of meeting each of them one on one to make whatever they need 100% unique. The company combines backgrounds in computer science, engineering, videography, graphic design, marketing, and entrepreneurship. Everyone at Argo Labs has owned or worked for small businesses and has done freelance work on their own.

SkySpecs, Inc. is a technology company based in Ann Arbor, Michigan, with an additional office in Amsterdam, Netherlands, that specializes in automating operations and maintenance for the wind energy industry through unmanned aerial vehicles. Founded in 2012, the company provides a range of services including analytics, wind turbine blade services, and engineering projects. Its offerings also encompass collaborative software solutions for managing and analyzing data from various sources, as well as digitization and planning for repair campaigns. Notably, SkySpecs has developed Horizon, a reporting software that serves as a central repository for operations and maintenance data related to wind turbine blades, facilitating task management, communication with third parties, and execution of large-scale repair projects. By leveraging its industry expertise and innovative technologies, SkySpecs aims to enhance productivity and efficiency for its clients within the renewable energy sector.

CureLauncher, LLC is a healthcare company based in Bloomfield Hills, Michigan, established in 2012. It specializes in providing clinical trial matching services that connect patients with new treatment options tailored to their specific health conditions and personal goals. In addition to supporting patients, CureLauncher also assists caregivers and healthcare professionals by offering a platform that identifies relevant clinical trials, facilitating access to innovative therapies. Through its services, CureLauncher aims to enhance the healthcare experience by helping individuals navigate their treatment options more effectively.

Axonia Medical's proprietary approach is to repair and restore damaged peripheral or central nervous systems using tissue-engineered nerve grafts. They are expected to bridge lost nervous tissue and jump-start regenerative mechanisms to achieve levels of functional recovery not possible with current technologies.

Algal Scientific Corporation, founded in 2009 and based in Plymouth, Michigan, specializes in the development and commercialization of algae-based products and technologies for various industries, including animal health, human nutrition, and water treatment. The company offers Algamune, a beta glucan derived from algae that enhances immune health in livestock and aquatic species, and AlgaGLUCAN, a similar product aimed at human nutraceuticals and functional foods. Additionally, Algal Scientific provides the Hypertrophic water treatment technology, which is designed to treat dissolved organics, nitrogen, and phosphorus in wastewater while generating a natural fertilizer byproduct. This technology serves customers in the food and beverage sector, including breweries, dairies, and meat producers, contributing to sustainable practices and resource conservation. The company also maintains an office in Beijing, China, to support its international operations.

TM3 Systems develops smart, mobile microgrid products for remote and off-grid power applications.

TM3 Systems develops smart, mobile microgrid products for remote and off-grid power applications.

Seelio is an online platform designed to help college students create and showcase their portfolios, enabling them to present their work and experiences to potential employers. Founded in 2011 and based in Ann Arbor, Michigan, Seelio focuses on building custom portfolio networks and galleries specifically for engineering, design, and business programs. The platform empowers students to document their learning journeys and exhibit their projects in a professional manner. Seelio has collaborated with prominent educational institutions, including the Massachusetts Institute of Technology, the University of Michigan, and the University of Texas at Austin. By providing this service, Seelio aims to enhance students' visibility to employment recruiters and facilitate their career readiness.

AutoBike, Inc. is a manufacturer based in Troy, Michigan, specializing in bicycles. Founded in 2011, the company has developed an innovative automatic shifting technology that enhances the riding experience by making it simple, comfortable, and enjoyable. AutoBike features this technology in its own line of bicycles, as well as providing it for integration into products from other bicycle original equipment manufacturers (OEMs).

Eloquence Communications is a healthcare IT company focused on enhancing care delivery through innovative communication solutions. It specializes in developing nurse-call systems utilizing its proprietary Eloquence technology, which facilitates bi-directional remote communication between patients and their care providers. The company's key offerings include the Eloquence Advanced Communication System (ACS) and the Eloquence Language Access Solution (LAS), both designed to ensure fast and accurate exchanges of information. By addressing language barriers and streamlining communication in healthcare settings, Eloquence Communications aims to improve patient outcomes and optimize workflow efficiency in healthcare facilities.

Quikly Inc., based in Detroit, Michigan, operates a digital marketing platform designed for consumer brands to execute frequent and highly-targeted marketing campaigns. Founded in 2012, Quikly focuses on helping marketers acquire, activate, and retain customers through solutions that include email, social media, mobile, loyalty, and local marketing. By leveraging consumer psychology, Quikly's platform effectively captures attention and motivates key consumer behaviors such as purchases, loyalty signups, and social engagement. Its technology aims to enhance digital activation and engagement within existing marketing channels, delivering measurable results and improved return on investment for brands in sectors like retail, dining, and consumer-packaged goods.

AlertWatch LLC, established in 2011 and headquartered in Ann Arbor, Michigan, specializes in producing clinical decision support systems for hospitals. The company's software products, AlertWatch:OR and AlertWatch:ICU, simplify patient monitoring by aggregating data from physiological monitors, anesthesia records, lab results, and medical history to provide real-time displays of a patient's condition. These intuitive tools help healthcare providers determine the normality or abnormality of a patient's status, with color-coded icons indicating green for normal, yellow for marginal, and red for abnormal conditions. AlertWatch:ICU serves as a secondary patient monitor and support system in intensive care units, offering additional functionalities such as data trends over time, SOFA and SIRS scores, nursing reminders, and alerts tailored to the ICU environment. The company's products are currently in use at the University of Michigan and other training hospitals across the United States.

Beet, Inc. specializes in providing diagnostic and analytical tools designed to enhance problem-solving capabilities for operations facing complex assembly and automation challenges. Founded in 2011 and headquartered in Plymouth, Michigan, with an additional office in China, the company offers a range of software solutions under its ENVISION brand. This includes ENVISION Enterprise SMART, ENVISION Sentinel SMART, and ENVISION System Scope, which cater to various operational scales and needs. Additionally, Beet provides a cloud-based Software-as-a-Service solution and consulting services. Its Process Visibility System (PVS) transforms manufacturing workflows by promoting proactive management and predictive maintenance, ultimately maximizing existing asset capacity and reducing unplanned downtime. The company's technology plays a crucial role in advancing manufacturers' efforts towards Industrial IoT and Industry 4.0, positioning them to improve production efficiency through real-time data utilization. Beet serves a diverse clientele, including automotive original equipment manufacturers and tooling manufacturers.

Advanced Battery Concepts, LLC is a battery technology development company based in Clare, Michigan, founded in 2008. The company specializes in the design and development of bi-polar lead-acid batteries, catering to a diverse range of markets including military, industrial, stationary, renewable, automotive, and motive sectors. Advanced Battery Concepts focuses on creating innovative battery electrode technologies that enhance performance by improving current density, active material utilization, energy density, and power density. These advancements enable clients to achieve better performance at lower production costs compared to traditional lead-acid batteries. The company was previously known as Advanced Battery Concepts Michigan, LLC until its name change in March 2011.

3D Biomatrix Inc. specializes in the design and manufacture of three-dimensional cell culture plates and scaffolds, specifically tailored for cellular assays used in drug discovery. Established in 2010 and located in Ann Arbor, Michigan, the company offers these innovative products in both 96- and 384-well plate formats. Its scaffolds are utilized by researchers and professionals in the pharmaceutical field, particularly for applications involving bone marrow, hepatocytes, and thymus. By facilitating 3D spheroid culture, 3D Biomatrix enables advancements in cancer and tumor research, supporting the development of more effective therapies.

Fusion Coolant Systems, Inc. specializes in the manufacturing and marketing of innovative coolant and lubrication systems that utilize supercritical carbon dioxide for various industrial applications. The company's product offerings include the Pure-Cut 1000 and LUBE-CUT 1600 machines, which deliver supercritical CO2 with varying lubrication rates tailored for different cutting processes. Fusion Coolant's patented CHiP Lube system represents a significant advancement in metalworking fluids, offering a cleaner alternative to traditional oil and water mixtures, thereby enhancing production rates and tool longevity while minimizing health hazards and environmental impact. The company's solutions are employed across multiple sectors, including medical, automotive, aerospace, and defense, and are supported by infrastructure products such as carbon dioxide storage tanks and pumps. Founded in 2009 and headquartered in Canton, Michigan, with an additional office in Saint-Priest, France, Fusion Coolant has established a strategic partnership with Air Liquide to bolster its market presence.

Larky, Inc. is a mobile and web platform that specializes in marketing and audience engagement. The company provides a mobile platform known as Nudge, which facilitates targeted geo-notifications, and Larky Classic, a mobile engagement solution that enhances communication with members. This platform supports local businesses, promotes cross-selling of products and services, boosts customer loyalty, and generates non-interest income for its clients. Larky also features a merchant-funded loyalty program that offers instant savings at local merchants, enhancing branding opportunities for participating organizations. The company serves a diverse range of clients, including financial institutions, health insurance providers, universities, and media companies across the United States and Canada. Founded in 2011 and based in Ann Arbor, Michigan, Larky was previously known as PerkPerk, Inc.

Algal Scientific Corporation, founded in 2009 and based in Plymouth, Michigan, specializes in the development and commercialization of algae-based products and technologies for various industries, including animal health, human nutrition, and water treatment. The company offers Algamune, a beta glucan derived from algae that enhances immune health in livestock and aquatic species, and AlgaGLUCAN, a similar product aimed at human nutraceuticals and functional foods. Additionally, Algal Scientific provides the Hypertrophic water treatment technology, which is designed to treat dissolved organics, nitrogen, and phosphorus in wastewater while generating a natural fertilizer byproduct. This technology serves customers in the food and beverage sector, including breweries, dairies, and meat producers, contributing to sustainable practices and resource conservation. The company also maintains an office in Beijing, China, to support its international operations.

Local Orbit is a developer of business management tools aimed at transforming the food system for the connected food economy. The company provides an elegant platform that facilitates multi-channel sales and streamlined purchasing for farmers, food producers, chefs, and independent distributors. By focusing on the needs of various stakeholders within the food supply chain, Local Orbit addresses the challenges of disconnected markets and inefficient communications. Its tools enable clients to manage their operations effectively, supporting emerging supply chains and fostering connections between wholesale buyers and local producers. Through its innovative solutions, Local Orbit seeks to enhance the overall efficiency of food distribution and business management in the evolving food landscape.

Envy Modular Wall Systems (MWS) specializes in the manufacturing and installation of lightweight modular panels that serve as temporary construction barriers. Founded by Doug Spear, the company emerged from extensive construction and business experience, aimed at addressing the diverse needs of various industries. The modular wall systems are engineered for strength and durability, originally developed for industrial construction barricade services. These panels are designed for ease of assembly and disassembly, utilizing 100% recycled materials, making them reusable after tear down and fully recyclable thereafter. Envy MWS caters to a range of sectors, including industrial construction, airports, casinos, malls, and stadiums, helping these companies initiate and complete their projects efficiently.

Mitostem, Inc. was founded in 2008 with the goal to drive innovation, and accelerate the scientific breakthroughs that will advance Stem Cell research and the field of Regenerative Medicine. MitoStem focuses on developing and commercializing novel technologies to advance stem cell research and the field of regenerative medicine. Stem cells have the ability to reproduce themselves (self-renew) or differentiate into each of the cell types found in the body. In the future, Pluripotent Stem Cells (PSC) will be able to replace diseased and damaged organs. Until recently, only stem cells derived from embryos were pluripotent. However, controversies are associated with using cells from embryos, and they can only be used for study of diseases that are diagnosed during assisted reproduction procedures (in vitro fertilization).

Millendo Therapeutics is a biopharmaceutical company dedicated to developing innovative treatments for endocrine diseases resulting from hormone dysregulation. The company focuses on creating distinct and transformative therapies that address significant unmet medical needs in this area. By leveraging scientific advancements, Millendo aims to develop novel compounds that can effectively treat complex conditions, ultimately enhancing clinical care and improving the quality of life for patients, families, and caregivers.

FreeStride Therapeutics, Inc. is focused on developing innovative therapies for companion animals, specifically targeting the underlying mechanisms of conditions such as arthritis and lameness, rather than merely alleviating symptoms. The company aims to create safe and effective treatments that restore the active lifestyles of horses, dogs, and cats, enhancing their quality of life. With a management team that possesses extensive experience in biotechnology, research, and drug development, FreeStride is committed to advancing veterinary healthcare. Their platform also includes the development of drugs aimed at treating inflammation and bone loss, thereby providing veterinary practitioners with access to high-quality therapeutic options for conditions like rheumatoid arthritis and osteoporosis.

Seelio is an online platform designed to help college students create and showcase their portfolios, enabling them to present their work and experiences to potential employers. Founded in 2011 and based in Ann Arbor, Michigan, Seelio focuses on building custom portfolio networks and galleries specifically for engineering, design, and business programs. The platform empowers students to document their learning journeys and exhibit their projects in a professional manner. Seelio has collaborated with prominent educational institutions, including the Massachusetts Institute of Technology, the University of Michigan, and the University of Texas at Austin. By providing this service, Seelio aims to enhance students' visibility to employment recruiters and facilitate their career readiness.

Axonia Medical's proprietary approach is to repair and restore damaged peripheral or central nervous systems using tissue-engineered nerve grafts. They are expected to bridge lost nervous tissue and jump-start regenerative mechanisms to achieve levels of functional recovery not possible with current technologies.

Celsee Diagnostics (formerly DeNovo Sciences) mission is to provide an easy to use platform for cancer research and diagnosis. Specifically, the company will sell an instrument system and reagent kit that allows for the separation, detection, and retrieval of circulating tumor cells (CTCs) from peripheral whole blood as an alternative to traditionally painful and invasive biopsies. Their company is developing a proprietary product that will not only allow researchers to identify and capture rare and difficult to harvest cancer cells in a microfluidic chip but also enable them to conduct downstream molecular analysis. This technology allows for the development of personalized therapies as well as the ability to monitor patient prognosis.

Oxus is a technology company that designs and manufactures oxygen concentrator products for several markets. Oxus has been in business for over 13 years. Oxus is proud to manufacture the Oxus Portable Oxygen Concentrator in the USA.

Blaze Medical Devices, LLC, founded in 2006 and based in Ann Arbor, Michigan, specializes in developing biomedical equipment aimed at assessing the properties of stored blood, particularly focusing on red blood cells (RBC). The company's principal product lines include the RBC Mechanical Fragilimeter™ systems, designed to test the mechanical fragility of red blood cells, and the RBC Hemolysis Tester systems, which incorporate the Fragilimeter™ functionality. These technologies facilitate integrated and standardized evaluations of blood damage, catering to a variety of industrial R&D and research applications. Blaze Medical Devices aims to support product developers and clinical researchers in understanding blood quality loss during storage, with future product lines targeting specific medical applications.

First Sense Medical is a developer of non-invasive medical devices focused on breast cancer screening. The company's flagship product, the Breast Exam, utilizes advanced thermal imaging technology to detect abnormal heat patterns in breast tissue that may indicate the risk of breast cancer. This automated testing device allows healthcare providers to input biopsy data, compare results against national benchmarks, and continuously update its algorithms for improved accuracy. By offering an integrated system for thermal profiling, First Sense Medical aims to equip doctors with essential information to enhance risk assessment for women of all ages.

FlockTAG is a mobile loyalty system that aims to enhance customer engagement for independent neighborhood businesses by simplifying the management of customer loyalty programs. It allows local merchants to establish a universal loyalty card network, enabling customers to earn points and rewards at participating venues. By connecting these businesses with consumers, FlockTAG creates meaningful rewards for customers while helping merchants increase profitability and reduce sales cannibalization. This innovative approach not only benefits businesses by driving customer loyalty but also provides students and other consumers with access to appealing discounts and deals on services they value.

Ventech, LLC is a manufacturer of mobile heating solutions based in Wixom, Michigan, founded in 2003. The company specializes in the development of the Liquid Heat Generator (LHG), an innovative auxiliary heating system designed for vehicle applications, including school buses, mass transit, and commercial vehicles. The LHG utilizes proprietary technology to generate heat quickly and efficiently, making it suitable for portable or mobile applications where an existing engine or motor is available. In addition to the LHG, Ventech offers a range of related products, including vehicle harnesses, control modules, mounting brackets, dashboard switches, and various other components. The company distributes its products through a network of dealers across the United States and Canada, targeting markets in transportation and consumer products while focusing on reducing fuel use, emissions, and enhancing overall vehicle comfort and engine longevity.

Empirical Bioscience, LLC is a developer and manufacturer of high-grade molecular biology reagents tailored for the life sciences industry in the United States. The company specializes in providing a comprehensive range of products, including PCR reagents optimized for standard, quantitative, and real-time PCR applications involving human, animal, and plant DNA. Their offerings also encompass next-generation sequencing, translational research, agricultural applications, and clinical diagnostics. Notable products include the rEVAlution qPCR Master Mix and the Taq 2x MeanGreen Master Mix. Empirical Bioscience emphasizes customization, allowing clients to configure products to specific requirements, and provides technical support for the development and launch of assays and products. Founded in 2009 and based in Grand Rapids, Michigan, the company was formerly known as Syzygy Biotech Inc. and adopted its current name in February 2014.

VNN, Inc. operates a prominent high school sports marketing and networking platform that serves as a digital hub for athletes, coaches, and fans. The platform enables athletes to upload videos, photos, stories, and scores, while allowing coaches to report game results to various media outlets. VNN is dedicated to enhancing the experience of high school sports by aggregating the fragmented market and providing advertising and promotional services. The company has established a significant presence, serving schools across multiple states, including Alabama, California, and Texas, and has gained a rapidly growing user base, with over 7 million fans engaging with the platform daily. Founded in 2010 and based in Grand Rapids, Michigan, VNN aims to transform the consumer experience in high school sports by leveraging technology and connectivity.

ePaySelect restructures monthly payments into smaller, more affordable payments that are much less than the customer expects. These automated payments are collected on paydays, held and paid to the lender on the due date. This eliminates late fees and protects credit ratings. Retailers benefit because smaller payments are inherently easier to sell. Customers include retailers like auto dealerships or anyone who needs help making monthly payments

Coliant Corporation, founded in 2001 and based in Warren, Michigan, specializes in manufacturing and distributing rugged electrical devices and cables tailored for the powersport environment, which includes motorcycles, scooters, snowmobiles, and personal watercraft. The company offers an extensive range of products, including powersport connectors, tire inflaters, battery charging solutions, and heated clothing items such as heated jacket liners and gloves. Additionally, Coliant provides various mounting systems, power distribution products, and direct power cables for devices like GPS units and radar detectors. Its products are available through dealers, distribution outlets, and online in markets spanning the United States, the United Kingdom, Europe, Asia, and Australia. The company also engages in developing wearable technologies aimed at enhancing smart apparel, enabling businesses to capitalize on the growing wearable technology market while safeguarding their brands.

Clean Emission Fluids, Inc. manufactures fueling and fluid dispensing solutions for the transportation industry. It also resells biofuels, clean diesel, and emission related fluids. The company’s product enables fleet operators, truck stops, gas stations, and municipal fleets to store and dispense fluids and fuels. Clean Emission Fluids, Inc. was incorporated in 2007 and is based in Grosse Pointe, Michigan.

Ix Innovations is dedicated to enhancing the usability of electrical test and measurement instrumentation.

Estrakon is a fabrication company specializing in the design and creation of electronic signage and custom marketing media using various materials. With advanced facilities in the USA, UK, and China, Estrakon focuses on producing high-quality, durable products tailored to exact specifications. The company employs cutting-edge construction techniques to ensure cost-effectiveness for large-scale production. Estrakon is committed to staying ahead through extensive research and development, offering innovative solutions such as patented edge-lit display technologies suitable for premium brand advertising and consumer displays. Effective communication with clients throughout the design and production process ensures that projects meet precise requirements.

Arbor Plastic Technologies, LLC is a manufacturer based in Sterling Heights, Michigan, specializing in the production and marketing of specialty additives and delivery systems for the plastic resin industry. Established in 2007, the company focuses on developing innovative solutions that enhance industrial processes. Its product offerings include process enhancer additives, multi-functional pellets, and foaming agents designed to improve production efficiency. Arbor Plastic Technologies' advanced additive delivery systems allow for the incorporation of various additives, such as UV stabilizers, fire retardants, and colorants, into a single pellet. This high-concentration approach provides clients with significant value by streamlining their production processes and enhancing the performance of their end products.

LEID Products, also known as Law Enforcement Intelligent Devices, LLC, specializes in the development and manufacturing of electronic lockers and tracking systems designed to enhance asset security for various organizations. Initially focused on assisting police departments in securing firearms and critical equipment through biometric access and electronic tracking, the company has expanded its offerings to include solutions for a wide range of business assets. Their products are utilized in diverse settings, such as amusement parks for tracking radios, libraries for managing books and media, and businesses for securing sensitive documents with restricted access. LEID Products aims to provide effective asset management solutions that ensure accountability and security across multiple sectors.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

Practical EHR Solutions, Pehr for short (pronounced “pear”), is a company that specializes in implementing and supporting electronic health records in physician groups. Pehr's mission is to improve patient outcomes. As healthcare professionals, the Pehr founders understand just how important a physician’s individuality is and have developed a unique and practical electronic health record implementation methodology to preserve that individuality. Pehr focuses on enhancing the physician experience by improving the physician’s work day, increasing the practice’s profitability and improving quality and safety. This results in quick acceptance and full functionality use of the EHR. It is this use of full feature functionality that patient outcomes can, and will, improve.

Empirical Bioscience, LLC is a developer and manufacturer of high-grade molecular biology reagents tailored for the life sciences industry in the United States. The company specializes in providing a comprehensive range of products, including PCR reagents optimized for standard, quantitative, and real-time PCR applications involving human, animal, and plant DNA. Their offerings also encompass next-generation sequencing, translational research, agricultural applications, and clinical diagnostics. Notable products include the rEVAlution qPCR Master Mix and the Taq 2x MeanGreen Master Mix. Empirical Bioscience emphasizes customization, allowing clients to configure products to specific requirements, and provides technical support for the development and launch of assays and products. Founded in 2009 and based in Grand Rapids, Michigan, the company was formerly known as Syzygy Biotech Inc. and adopted its current name in February 2014.

ArborWind LLC is a green energy company based in Ann Arbor, Michigan, specializing in the manufacture and installation of vertical axis wind turbines. Founded in 2010 by Frank Fike, James Vincke, and Dilip Nigam, ArborWind focuses on providing economical and efficient energy solutions for rural areas. Its turbines are designed to generate electricity for diverse applications, including agriculture, industrial and commercial sectors, housing projects, and both urban and rural communities. By utilizing wind energy, ArborWind enables its customers to meet their energy needs while minimizing costs, transmission losses, and logistical challenges commonly associated with traditional energy sources.

Reveal Design Automation, Inc. is an electronic design automation start-up based in Ann Arbor, Michigan, established in 2009. The company specializes in developing software tools for the formal verification of complex semiconductor chip designs. Its flagship product, Reveal-AV, utilizes architectural equivalence methodology to enable full-design verification of various core architectures, including CPU, MPU, DSP, GPU, and microcontroller RTL against their instruction set architecture specifications. Reveal's solutions significantly enhance efficiency, allowing verification processes that typically take days with competing tools to be completed in hours. This capability helps chip designers reduce verification expenses, accelerate time-to-market, and increase confidence in design correctness, ultimately saving millions of dollars in development costs.

Zipments is a local logistics platform that specializes in same-day delivery services for both businesses and individuals. By utilizing its website and mobile app, customers can conveniently request local deliveries, while retailers can integrate Zipments' API into their online shopping carts to offer seamless delivery options. The company caters to a diverse range of sectors, including retail, professional services, and restaurants, providing an efficient and cost-effective solution for local deliveries. Zipments' on-demand platform allows users to track packages in real time and receive instant notifications, enhancing the overall delivery experience. Additionally, it serves consumers seeking assistance with personal deliveries, making it a versatile option for various delivery needs.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

NextCAT is a company focused on commercializing innovative catalysts for biodiesel production. Developed at the National Biofuels Energy Lab at Wayne State University, these catalysts are designed to reduce production costs for biodiesel producers by optimizing the use of feedstock and streamlining the production process. With a team of experts in catalysis and a seasoned management team, NextCAT aims to transform the biodiesel industry, making it more efficient and environmentally friendly. The company's approach not only enhances production efficiency but also contributes to reducing dependence on foreign oil, positioning NextCAT as a key player in the advancement of sustainable biodiesel solutions.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Fulcrum Composites Inc is a Michigan based company dedicated to developing new products and bringing them to market. Although their product portfolio is diverse, they are linked by common themes of structural efficiency obtained by synergistic and often unconventional combinations of materials and manufacturing processes.

Armune BioScience, Inc. is a medical diagnostics company based in Kalamazoo, Michigan, that specializes in the development and commercialization of blood tests designed to detect cancer through indicators from the body’s immune response. Founded in 2007, the company focuses on creating diagnostic and prognostic tests for prostate, lung, and breast cancers, enabling personalized treatment decisions for both physicians and patients. One of its key offerings is APIFINY, a non-PSA blood test that assesses the risk of prostate cancer by measuring specific biological markers linked to the immune system. Armune markets its products directly to healthcare providers, including primary-care physicians, urologists, and oncologists. The company’s technological foundation is rooted in research conducted at the University of Michigan, which has been recognized in prominent scientific publications. Armune BioScience operates as a subsidiary of Exact Sciences Corporation, allowing it to leverage additional resources for its innovative healthcare solutions.

Inventure Enterprises Inc. is a management consulting and technology services firm based in East Lansing, Michigan. Founded in 2002, the company specializes in providing performance solutions and information technology application services to businesses and government entities. Its offerings include secure background checks, homeland security and defense consulting, human capital and talent management, strategy and change management, as well as customer relationship management. In addition, Inventure Enterprises provides application development and modernization, business intelligence services, and mobile application solutions to enhance operational efficiency. The firm's idView suite manages the background check process from initial requests to final results. Inventure Enterprises serves a diverse range of clients across various sectors, including federal and state government, defense, security, manufacturing, financial services, energy, transportation, and healthcare, both domestically and internationally.

Current Motor Company is an Ann Arbor, Michigan-based manufacturer specializing in electric motor scooters designed for urban commuters. The company develops and produces all-electric maxi-scooters that are zero-emission and environmentally friendly, catering to the growing demand for sustainable transportation solutions. Current Motor's scooters can reach speeds of up to 70 MPH and offer a range of approximately 50 miles on a single charge, utilizing standard household outlets for recharging. The company has established a strategic partnership with Dakkota Integrated Systems and sells its products through a network of dealers. In addition to scooters, Current Motor also manufactures electric hub motors and solar charging stations, further enhancing its commitment to energy-independent transportation options.

NextCAT is a company focused on commercializing innovative catalysts for biodiesel production. Developed at the National Biofuels Energy Lab at Wayne State University, these catalysts are designed to reduce production costs for biodiesel producers by optimizing the use of feedstock and streamlining the production process. With a team of experts in catalysis and a seasoned management team, NextCAT aims to transform the biodiesel industry, making it more efficient and environmentally friendly. The company's approach not only enhances production efficiency but also contributes to reducing dependence on foreign oil, positioning NextCAT as a key player in the advancement of sustainable biodiesel solutions.

InfoReady Corporation is a software development company based in Ann Arbor, Michigan, specializing in web-based solutions for higher education institutions. Founded in 2010, InfoReady offers tools designed to streamline workflow and enhance the grant application process. Its primary products include InfoReady Review, which connects researchers with relevant research grants, and InfoReady Thrive, a marketplace for scholarships, fellowships, and internships. The platform integrates various functions such as form building, document collection, and reporting into a single user-friendly interface, improving productivity and communication among academic teams. With a client base of over 200 institutions worldwide and a client retention rate exceeding 90%, InfoReady is recognized for its commitment to operational efficiency and effective process management, ultimately enhancing transparency and engagement within academic environments.

Sentio MMG® is a surgical access tool. It is intended to locate and map motor nerve roots and their peripheral extensions originating from spinal levels C3-T1 and L2-S2. Sentio MMG® smart-sensors are different from all other forms of neuromonitoring electrodes. In contrast to electromyography, or EMG, which relies on needles to detect subtle changes in electrical signals in muscle, Sentio MMG® smart-sensors employ proprietary accelerometer technology. These non-invasive accelerometer-based sensors measure MMG (mechanomyography) activity, or the mechanical “twitch” associated with muscle contraction. When MMG activity is detected, the surgeon is provided with a ‘STOP’ alert indicating a nerve has been identified. The result is an intuitive, surgeon-directed tool for establishing safe access in a variety of surgical applications. Sentio MMG® was specifically designed to facilitate safe lateral transpsoas surgery. Sentio believed there was a better way to identify and map nerves during lateral surgery that did not require EMG. Design objectives included:

Trapelo Health is a healthcare technology company based in Cambridge, Massachusetts, that specializes in precision oncology. Founded in 2009, the company has developed a collaborative decision support platform that provides evidence-based reports in molecular oncology for physicians, payers, and labs. This platform facilitates the alignment of molecular test results with associated therapies, enabling healthcare providers to efficiently identify appropriate treatments based on the latest medical evidence. Trapelo Health aims to enhance the use of precision medicine by fostering collaboration among oncologists, molecular labs, and payers, ultimately supporting effective cancer care through the analysis of cancerous tissues and the generation of genomic insights.

Mandy & Pandy teaches kids Chinese in a fun and easy way through books, CDs, DVDs, toys, fashion, and television. Similarly, Mandy & Pandy teaches English to Chinese-speaking children.

RealBio Technology, Inc. is a life science product development company based in Kalamazoo, Michigan, founded in 2009. The company specializes in innovative cell and tissue culture technologies designed to support the growth, expansion, differentiation, and collection of both human and non-human cells. RealBio Technology has developed the Nth Degree System, a single-use disposable 3D perfusion bioreactor that enhances in vitro cell cultures by mimicking the natural conditions of in vivo environments. This proprietary technology allows for the creation of nutrient and gas gradients within the culture chamber, facilitating advanced applications in regenerative medicine, in-vitro modeling, and bio-production. The company serves researchers and healthcare professionals, contributing to advancements in life sciences research.

Algal Scientific Corporation, founded in 2009 and based in Plymouth, Michigan, specializes in the development and commercialization of algae-based products and technologies for various industries, including animal health, human nutrition, and water treatment. The company offers Algamune, a beta glucan derived from algae that enhances immune health in livestock and aquatic species, and AlgaGLUCAN, a similar product aimed at human nutraceuticals and functional foods. Additionally, Algal Scientific provides the Hypertrophic water treatment technology, which is designed to treat dissolved organics, nitrogen, and phosphorus in wastewater while generating a natural fertilizer byproduct. This technology serves customers in the food and beverage sector, including breweries, dairies, and meat producers, contributing to sustainable practices and resource conservation. The company also maintains an office in Beijing, China, to support its international operations.

Azenic is a dental device company focusing on unmet market needs in the dental profession with emphasis on novel disposable instruments. Axenic Dental was founded in 2008 and is based in Kalamazoo, Michigan.

Michelle's Miracle, Inc., operating under the brand name Cherry Works, specializes in producing and selling dietary supplements derived from Montmorency tart cherry concentrate. Based in Traverse City, Michigan, the company offers a range of products including concentrates and tablets designed to support daily wellness, exercise recovery, muscle and joint relief, sleep quality, and overall health for both adults and children. Founded in 2001, Michelle's Miracle serves customers through online sales and retail partnerships with health food stores and grocery stores across North America. The company also provides private labeling services and seeks partnerships for custom-formulated supplements.

White Pine Systems, LLC (dba SPINN) is dedicated to delivering a complete solution for consumer-engaged healthcare that compliments existing health information technology investments. Their Internet-based patient engagement systems are at the core of the rapidly emerging “connected health” movement. Connected health uses technology to provide access to critical personal health information, improve communication between healthcare providers, patients and their families, and better manage chronic conditions to facilitate living normal lives.

Epsilon Imaging, Inc. is a company that specializes in the design and development of algorithms and software for cardiac ultrasound medical imaging. Based in Ann Arbor, Michigan, the company was founded in 2008 and was formerly known as Ultrasound Medical Devices, Inc. Epsilon Imaging offers a suite of vendor-neutral software applications, including EchoInsight Pro, EchoInsight Stand-alone, and EchoInsight Applications, which enhance the efficiency and effectiveness of echocardiography practices. These solutions facilitate streamlined workflows, innovative visualization, and analysis technologies to improve the quality and standardization of cardiac diagnostics. The company also provides robust support services, including expert consultation for echocardiography strain imaging programs, ensuring that clinicians receive comprehensive assistance to optimize their practices. Epsilon Imaging is dedicated to transforming the cardiac diagnostic workflow and enhancing patient management through its advanced technologies.

Base4 Biotechnology is a company focused on innovating RNA-targeted therapeutics through the development of novel small molecule modulators aimed at addressing previously untreatable diseases. Utilizing a proprietary structure-based discovery platform, Base4 combines advanced in silico technologies with rigorous experimental validation to explore and harness the potential of RNA targets across various therapeutic areas, including neurology, oncology, and rare diseases. The company's approach aims to facilitate the creation of transformative medical solutions, ultimately advancing the healthcare industry.

OcuSciences is a medical diagnostic device company that specializes in developing an innovative ocular imaging technique known as flavoprotein fluorescence (FPF). This non-invasive technology is designed to detect and monitor retinal metabolic dysfunction, allowing for the early identification of various retinal diseases, including diabetic retinopathy, macular degeneration, and glaucoma. By assessing retinal metabolic activity, OcuSciences aims to enhance the ability of ophthalmologists to diagnose and manage ocular manifestations of diabetes and related conditions. The company's focus on retinal mitochondrial dysfunction positions it at the forefront of advancing ocular health diagnostics.

Arbor Photonics, LLC is a company based in Ann Arbor, Michigan, that specializes in the development of advanced optical-fiber technology. The firm focuses on creating fiber laser systems that combine high beam quality with significant optical power. Its innovative power laser technology is designed for various applications, particularly in laser materials processing and defense sectors.

Biotectix, LLC is a company that specializes in the development and commercialization of bioactive conductive polymer electrodes and coatings for medical devices. Founded in 2007 and based in Richmond, California, Biotectix produces innovative products such as Amplicoat, which optimizes communication between human tissue and medical device electrodes, and Tecticoat, a conductive coating for textiles and materials that provides electrical conductivity and shielding. Their products are utilized in a wide range of medical devices, including retinal and cochlear prostheses, pacemakers, biosensors, and deep brain stimulators. Biotectix primarily serves medical device manufacturers, offering solutions that enhance device stability, minimize foreign body reactions, and improve long-term electrical performance. As of September 2017, Biotectix operates as a subsidiary of Heraeus Medical Components LLC.

Creative Byline, Inc. provides an online service that enables writers and editors to connect according to their interests and qualifications. Its Website brings together editors from various publishers and enables them to indicate their interests, as well as make a direct connection between the writer and interested editors. The company was founded in 2007 and is based in Holland, Michigan.

Armune BioScience, Inc. is a medical diagnostics company based in Kalamazoo, Michigan, that specializes in the development and commercialization of blood tests designed to detect cancer through indicators from the body’s immune response. Founded in 2007, the company focuses on creating diagnostic and prognostic tests for prostate, lung, and breast cancers, enabling personalized treatment decisions for both physicians and patients. One of its key offerings is APIFINY, a non-PSA blood test that assesses the risk of prostate cancer by measuring specific biological markers linked to the immune system. Armune markets its products directly to healthcare providers, including primary-care physicians, urologists, and oncologists. The company’s technological foundation is rooted in research conducted at the University of Michigan, which has been recognized in prominent scientific publications. Armune BioScience operates as a subsidiary of Exact Sciences Corporation, allowing it to leverage additional resources for its innovative healthcare solutions.

Fulcrum Composites Inc is a Michigan based company dedicated to developing new products and bringing them to market. Although their product portfolio is diverse, they are linked by common themes of structural efficiency obtained by synergistic and often unconventional combinations of materials and manufacturing processes.

ERT Systems, founded in 2005 by John Ellis and Dennis Carmichael, specializes in automated resource tracking systems designed for emergency responders. Leveraging Ellis's extensive experience as a firefighter, the company addresses the critical challenge of managing resources during chaotic emergency situations. ERT Systems offers a fully automatic wireless solution that tracks and locates personnel and equipment in real-time during emergencies. This innovative system enhances the safety of both responders and the public by providing crucial situational awareness without adding unnecessary overhead for incident commanders. The company's first product was successfully deployed at the Macomb College Firefighter Training Facility in 2006, marking the beginning of its commitment to improving emergency response through advanced technology.

3IS is a specialized research company focused on the global automotive electronics industry. It operates a comprehensive database covering all vehicle domains, offering services such as hardware and software research, design, development, and testing, as well as competitive analysis and vehicle investigation. This enables clients to gain accurate and relevant insights for technical or commercial data within the industry.

Aursos, Inc. is a biotechnology company focused on the development of innovative treatments for bone loss. Founded in 2007 and headquartered in Kalamazoo, Michigan, with an additional office in Houghton, Michigan, Aursos is known for its black bear PTH (BB-PTH) 1-34, aimed at preventing and treating osteoporosis, including cases related to chronic immobilization. In addition to its pharmaceutical developments, the company has also created implantable orthobiological technology designed for bone grafting procedures, effectively addressing conditions such as bone voids, non-union fractures, and spinal fusions.

Afid Therapeutics, Inc. is engaged in the development of chemical and biochemical technologies aimed at the design, discovery, delivery, and development of new pharmaceuticals. The company's product offerings encompass a wide array of chemical entities, including lactones, esters, hydroxy cyclopentane carboxylic acids, amino acids, and advanced diamines, among others. Afid Therapeutics is also focused on creating a platform of chiral chemical entities that mimic the structural and reactive properties of biomolecules, facilitating various life processes. The company provides numerous ring systems for screening collections, which include a diverse range of compounds such as piperazines, oxazolines, morpholines, and quinolines. Additionally, it explores functionalities involving sulfonamides, phosphonates, and carbohydrate derivatives. The technological foundation of Afid Therapeutics leverages the structural diversity of carbohydrates to enable therapeutic interventions across multiple disease spectra, including infections, cancer, autoimmune disorders, cardiovascular diseases, diabetes, and neurological disorders such as Alzheimer’s. The company targets a variety of biological molecules, including kinases, glycosidases, and nucleic acids. Founded in 2003, Afid Therapeutics is headquartered in Lansing, Michigan.

Global Energy Innovations Inc. provides alternate energy services. The Company manufactures fuel cell energy systems. Global Energy Innovations serves customers worldwide.

Emiliem, Inc. is a private biotechnology company based in San Francisco, California, dedicated to the development of novel oncology therapeutics as well as treatments for inflammatory and metabolic diseases. Established in 2005, the company focuses on understanding the molecular determinants of target modulation, which informs the efficacy of its therapeutics and potential adverse drug reactions. Emiliem's product pipeline includes EM101, a low molecular weight compound with additional kinase and cell cycle inhibitory activity; EM370, a series demonstrating direct Akt binding and inhibitory action against Akt-activating kinases; and EM400, currently in optimization with a confirmed multi-kinase inhibitor profile. In addition to drug development, Emiliem is also engaged in identifying diagnostic markers for rare diseases and utilizes computational methods to predict patient outcomes.

Vestaron Corporation is a developer and manufacturer of peptide-based biologic crop protection products, designed to enhance the safety, efficacy, and sustainability of agricultural practices. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides, including Spear-T for treating thrips in vegetables and ornamentals, Spear-Lep for fruits and field crops, and Leprotec for broader field use. The company is recognized for its commitment to addressing resistance issues in pests while ensuring safety for workers, beneficial organisms, and the environment. Vestaron has received several awards for its innovative biocontrol solutions, including the Bernard Blum Award and the Green Chemistry Challenge Award, reflecting its leadership in the field of sustainable agriculture.

iTrack LLC is a developer of advanced autonomous navigation and tracking software designed to accurately monitor personnel and vehicles. The company's innovative technology addresses the limitations of GPS by enabling precise tracking in environments where GPS may be unavailable. Its software features user-friendly graphical interfaces for operating and maintaining the system, as well as controls for autonomous vehicles and local position tracking. In collaboration with Royal Oak Industries, a Michigan-based engineering and manufacturing company, iTrack aims to commercialize its Department of Defense-funded technology, which has received significant financial backing. The company plans to transition its operations from the Oakland University Business Incubator to the Royal Oak Industries headquarters in Lake Orion, Michigan, to leverage additional resources and support for its commercialization efforts.

The Advisory Board Company is a provider of research services aimed at leaders in the healthcare industry, serving over 2,700 hospitals, health systems, universities, and mission-driven organizations in the United States and globally. With a team of more than 900 researchers, experts, and consultants, the company focuses on addressing critical issues faced by its members and delivering insights for optimal performance. Its offerings include personalized digital subscriptions, executive education, decision-support tools, and consulting services, tailored to the unique needs of each institution. The Advisory Board Company helps healthcare organizations navigate complex challenges such as clinical workforce management and turnover through actionable strategies and practical resources.

Compendia Bioscience focuses on harnessing a comprehensive collection of cancer genomic data to enhance patient treatment outcomes. The company specializes in providing genomic data and analytical tools specifically tailored for oncology drug discovery. By enabling researchers to validate biomarker and gene target discoveries, Compendia plays a crucial role in the advancement of cancer diagnostics and the development of effective treatments. Through its innovative approach, the company aims to significantly impact the landscape of cancer care.

RazorThreat, Inc. is a cybersecurity software company based in Pontiac, Michigan, founded in 2005. It specializes in developing threat information and risk management solutions that safeguard intellectual capital and personally identifiable information from cyber attacks. RazorThreat's flagship product, the Threat Analysis Console (TAC), offers a comprehensive suite of tools, including an Inter-domain Communication Engine that normalizes data from various security systems, a Threat Intelligence Engine that transforms disparate data into actionable insights, and a Risk Intelligence Engine that maps vulnerabilities against threat intelligence. This approach allows organizations to identify and remediate network threats effectively. The company emphasizes a personalized defense strategy tailored to individual client environments, leveraging existing security investments to combat targeted and persistent attacks. Additionally, RazorThreat provides integration and training services to enhance the implementation of its solutions, ensuring businesses and governments remain vigilant against unauthorized network activity.

Vestaron Corporation is a developer and manufacturer of peptide-based biologic crop protection products, designed to enhance the safety, efficacy, and sustainability of agricultural practices. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides, including Spear-T for treating thrips in vegetables and ornamentals, Spear-Lep for fruits and field crops, and Leprotec for broader field use. The company is recognized for its commitment to addressing resistance issues in pests while ensuring safety for workers, beneficial organisms, and the environment. Vestaron has received several awards for its innovative biocontrol solutions, including the Bernard Blum Award and the Green Chemistry Challenge Award, reflecting its leadership in the field of sustainable agriculture.

NRG Dynamix, Inc. is a Michigan-based company specializing in advanced hydraulic solutions, including hydraulic hybrid power trains, piston accumulators, pressure vessels, and variable displacement gear pumps. Founded in 2004 and formerly known as Hybra-Drive Systems, LLC, the company targets various markets such as off-highway vehicles, marine applications, alternative fuels, and energy storage. NRG Dynamix also serves the U.S. Department of Defense and has developed patented technologies that enhance fuel efficiency and energy storage in on-highway vehicles. With a focus on innovation, NRG Dynamix is poised to expand its offerings to traditional industries utilizing hydraulic systems.

XG Sciences, Inc. is a manufacturer of graphene nanoplatelets based in Lansing, Michigan. The company produces and sells its xGnP brand of graphene nanoplatelets, which are specialized carbon nanoparticles available in various sizes and thicknesses. These materials are utilized in a wide range of applications, including automotive, aerospace, medical, electronics, and energy storage. XG Sciences offers bulk materials for use in polymeric and metallic composites, coatings, and concrete additives, as well as formulated dispersions for conductive applications in printing and coating. Additionally, the company develops energy storage materials for lithium-ion and lead-carbon batteries and provides thermal management solutions, including thermal interface materials. Founded in 2006, XG Sciences operates a manufacturing plant with significant production capacity and collaborates with various research organizations, commercial entities, and development partners globally.

Phrixus Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing therapies for heart failure. Incorporated in 2006 and based in Ann Arbor, Michigan, the company is known for its key product, Carmeseal, which is designed to treat heart failure, particularly in patients with Duchenne muscular dystrophy. Carmeseal works by repairing muscle damage, offering a novel approach to managing acute heart failure. Phrixus Pharmaceuticals aims to provide cost-effective and efficient treatment options that enable quicker recovery for patients suffering from this serious condition.