Big Pi Ventures

Big Pi Ventures, established in 2017 and headquartered in Athens, Greece, is an early-stage venture capital firm that invests in innovative technology companies. The firm focuses on backing founders developing proprietary technologies that address significant global challenges, with a particular interest in computer science, artificial intelligence, life sciences, and climate technologies. Big Pi Ventures typically invests between $0.5 million to $3 million per round, targeting both Greece and the United States. The firm's team, comprising experienced entrepreneurs, provides not only capital but also strategic guidance and operational support to help portfolio companies succeed.

Alex Eleftheriadis

Partner

Achilleas Gravanis

Venture Partner

Cassandra Kosmidou

Associate

Melina Mai

Technology Investment Associate

20 past transactions

Astrato Analytics

Seed Round in 2025
Astrato Analytics is a cloud-native business intelligence platform designed to help organizations build, explore, and share real-time data insights. The platform caters to the modern data stack and allows users to create interactive dashboards while supporting features such as self-service reporting and writeback capabilities. By integrating with leading cloud data warehouses like Snowflake and BigQuery, Astrato aims to enhance data accessibility and foster data adoption across organizations. Founded by the team behind Vizlib, the company leverages deep expertise in business intelligence and intuitive design to provide fast, effective, and personalized analytics solutions for users seeking to uncover meaningful insights.

Corsmed

Seed Round in 2024
Corsmed AB, founded in 2016 and based in Lund, Sweden, specializes in developing advanced cloud infrastructures for medical imaging applications, particularly focusing on magnetic resonance imaging (MRI). The company is known for its innovative MRI simulation platform, often likened to a “flight simulator of MRI,” which serves as an educational tool for current and future MRI operators. This platform allows users, including medical professionals, students, and educators, to practice on virtual MRI scanners, enhancing their skills in a safe environment. Additionally, it provides a research module that enables users to build and test pulse sequences on anatomical models without needing access to a physical MRI scanner. Through these offerings, Corsmed aims to improve the training and capabilities of medical personnel globally.

Navenio

Series A in 2023
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Dyania Health

Seed Round in 2022
Dyania Health focuses on enhancing clinical research efficiency through its proprietary Synapsis AI platform. This technology automates manual chart reviews, a traditionally labor-intensive process in healthcare, allowing clinicians to provide timely and effective patient care. Dyania's system is utilized by large healthcare organizations to facilitate enterprise-wide clinical trial pre-screening, conduct automated chart reviews for observational studies, and streamline complex registry reporting. By leveraging artificial intelligence and machine learning to analyze unstructured electronic medical record data, Dyania Health significantly reduces manual workloads, improves the accuracy of clinical research, and enhances the identification of potential candidates for clinical drug trials.

Bryq

Seed Round in 2022
Bryq, established in 2014, is a talent assessment platform headquartered in Nicosia, Cyprus, with offices in London and Athens. It specializes in bias-free hiring, pre-employment assessments, and internal mobility. Bryq's platform leverages validated psychometrics to help companies diversify their teams and build organizational culture. By identifying leadership qualities and innovation potential in candidates, Bryq's customizable 'Indicators' provide employers with valuable insights, enhancing the hiring process and reducing time to hire.

OrthoSon

Series A in 2022
OrthoSon Limited is a medical device company based in Oxford, United Kingdom, focused on developing a minimally-invasive treatment for chronic low back pain. Established in 2015, the company has created a novel bio-structural gel implant that is injected into the nucleus of the intervertebral disc. This innovative procedure follows the natural fissures of degeneration, allowing the gel to restore the disc's mechanical function and alleviate pain. By providing a motion-preserving alternative to traditional spinal fusion techniques, OrthoSon aims to offer patients a safe and effective option that takes less than 30 minutes and does not require incisions.

Cylinder

Series A in 2022
Founded in 2021, Cylinder delivers personalized, clinician-backed care to those suffering from digestive issues through its virtual health platform and has helped nearly 100K members to date. Cylinder's platform offers dynamically updated content and care plans designed to improve engagement and outcomes. Members enjoy access to a dedicated care team nationwide, including health coaches, registered dietitians, and GI doctors. Cylinder’s vision is to create a world where people receive convenient, personalized, and affordable access to the quality digestive health care they need to improve their overall health. Trusted by businesses including Texas A&M University, US Foods, and more, Cylinder showcases up to 5:1 ROI and an average of 13% employee engagement. Learn more at cylinderhealth.com.

Navenio

Venture Round in 2021
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Intelligencia AI

Series A in 2021
Intelligencia AI is an enterprise SaaS company that specializes in applying machine learning technology to enhance clinical development strategies. The company has developed a cloud-based platform that utilizes predictive analytics to assess, quantify, and mitigate risks associated with clinical trials. By estimating the probability of success for various trial designs, Intelligencia's platform allows healthcare organizations to optimize their approaches before initiating trials. This proactive risk management not only helps to save time and resources for clinical trials but also facilitates quicker access to innovative therapies for patients.

Anodyne Nanotech

Seed Round in 2021
Anodyne Nanotech is a preclinical-stage biotechnology firm that focuses on developing innovative transdermal drug delivery systems. Founded in 2019 by Jake Lombardo, Konstantinos Tzortzakis, and Hojatollah Rezaei Nejad, the company has created a platform known as Hero Patch. This technology utilizes porous microneedles to deliver clinically significant doses of macromolecules, such as monoclonal antibodies and small molecules, in a cost-effective manner. Anodyne's approach aims to simplify the administration of medications for chronic diseases, providing healthcare professionals with efficient alternatives to traditional injection methods.

Altered

Seed Round in 2020
Altered is a synthetic media company focused on democratizing digital audio through innovative technology. It offers a next-generation audio editor that incorporates multiple Voice AI technologies, enabling the production of high-quality voice content. The company's digital voice workstation utilizes deep learning to enhance creativity for audio professionals, businesses, and prosumers, allowing them to create voice experiences without being constrained by hardware limitations. In addition to its editing tools, Altered provides voice content, voice cloning applications, and recording services, positioning itself as a leader in the evolving landscape of voice technology.

Bryq

Seed Round in 2020
Bryq, established in 2014, is a talent assessment platform headquartered in Nicosia, Cyprus, with offices in London and Athens. It specializes in bias-free hiring, pre-employment assessments, and internal mobility. Bryq's platform leverages validated psychometrics to help companies diversify their teams and build organizational culture. By identifying leadership qualities and innovation potential in candidates, Bryq's customizable 'Indicators' provide employers with valuable insights, enhancing the hiring process and reducing time to hire.

TileDB

Series A in 2020
TileDB, Inc. develops and maintains a system for managing multi-dimensional array data, particularly suited for scientific applications. The company's offerings include TileDB Embedded, a storage engine, and TileDB Cloud, which facilitates the management of array data in the cloud. Designed to handle a variety of data types, including unstructured multimodal data, TileDB addresses the complexities encountered in fields such as genomics, biomedical imaging, and multiomic data analysis. This foundational software is utilized by research teams in pharmaceuticals and biotechnology to enhance their data platforms and drive scientific discovery. Founded in 2017 and headquartered in Cambridge, Massachusetts, TileDB also has a location in Athens, Greece.

Navenio

Series A in 2020
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Athroa Innovations

Seed Round in 2019
Athroa Innovations, founded in 2019 and based in Athens, Greece, specializes in commercializing deep science inventions through the licensing of intellectual property (IP). The company provides innovators with an alternative to launching start-ups by facilitating IP licensing, allowing them to concentrate on advancing their core research. Athroa Innovations also offers a competitive advantage in prototyping, leveraging Greece's resources to support innovators. In addition to its licensing model, the company engages in venture building and invests in sectors such as health technology, clean technology, and food technology.

Accusonus

Series A in 2019
Accusonus, Inc., established in 2015, specializes in developing innovative software tools for the professional music industry and consumer electronics sector. Based in Lexington, Massachusetts, with additional offices in Greece, the company offers a range of products including Drumatom (drum bleed reduction), Drumatom Player (leakage suppression), ERA-D (sound processing), and Regroover (AI-driven beat machine). Accusonus also provides embedded software for speech enhancement in consumer electronics. Their patented Machine Learning and Artificial Intelligence technology streamlines sound processing workflows, making audio repair and music creation more accessible and efficient.

TileDB

Seed Round in 2019
TileDB, Inc. develops and maintains a system for managing multi-dimensional array data, particularly suited for scientific applications. The company's offerings include TileDB Embedded, a storage engine, and TileDB Cloud, which facilitates the management of array data in the cloud. Designed to handle a variety of data types, including unstructured multimodal data, TileDB addresses the complexities encountered in fields such as genomics, biomedical imaging, and multiomic data analysis. This foundational software is utilized by research teams in pharmaceuticals and biotechnology to enhance their data platforms and drive scientific discovery. Founded in 2017 and headquartered in Cambridge, Massachusetts, TileDB also has a location in Athens, Greece.

Intelligencia AI

Seed Round in 2018
Intelligencia AI is an enterprise SaaS company that specializes in applying machine learning technology to enhance clinical development strategies. The company has developed a cloud-based platform that utilizes predictive analytics to assess, quantify, and mitigate risks associated with clinical trials. By estimating the probability of success for various trial designs, Intelligencia's platform allows healthcare organizations to optimize their approaches before initiating trials. This proactive risk management not only helps to save time and resources for clinical trials but also facilitates quicker access to innovative therapies for patients.

Fieldscale

Series A in 2018
Fieldscale is a company based in Thessaloniki, Greece, that specializes in developing cloud-based simulation software for the touch sensor industry. Its flagship product, SENSE, provides advanced capacitive touch sensor simulation capabilities, enabling engineers to conduct electric design and analysis with enhanced accuracy and efficiency. The software employs sophisticated algorithms within an intuitive user interface, allowing for the execution of complex simulations, including electric field analysis and assessments of dielectric breakdowns and partial discharges. By facilitating thousands of analyses and various scenarios within a single day, Fieldscale empowers engineers to optimize sensor designs while reducing power consumption, thereby improving the overall design process for touchscreen products. Founded in 2015, the company aims to provide solutions that help users achieve optimal design outcomes more quickly than their competitors.

Balena

Funding Round in 2018
Balena Inc. operates a platform that provides comprehensive tools for building, deploying, and managing fleets of connected Internet of Things (IoT) devices. The company offers a range of products, including balenaCloud, balenaOS, balenaFin, balenaEngine, balenaEtcher, and openbalena, which facilitate application development, device deployment, and management for fleet owners. Balena's infrastructure enables developers to focus on application growth while managing, monitoring, and updating devices through a web dashboard, API, CLI, and SDK. The platform supports Linux containers and open technologies, allowing for seamless firmware deployment and compatibility with various programming languages and libraries. Founded in 2013 and based in Seattle, Washington, Balena also has offices in Greece and the United Kingdom. The company was previously known as Resin, Inc. until its rebranding in October 2018.
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