Big Pi Ventures

We invest in the dreamers, the thinkers, and the doers who have the ambition and persistence to change the world with their innovative tech. We will be your partner and champion throughout your journey. Big Pi is a venture capital fund, investing in founders working on proprietary technologies that help solve big problems. We are excited by teams building solutions based on advances in computer science, artificial intelligence, life sciences and climate technologies. Some of our portfolio companies are already transforming their respective industries. We’ve been where you are at. Some of our team members have built very successful businesses of their own (and failed multiple times as well). To really help you reach the promise land, it takes more than just investing money. We have just launched our second fund and are ready to invest in the most exciting businesses of the future.

Marco Veremis

Partner

20 past transactions

Astrato Analytics

Seed Round in 2025
Astrato Analytics is a cloud-native business intelligence platform designed to help organizations build, explore, and share real-time data insights. The platform caters to the modern data stack and allows users to create interactive dashboards while supporting features such as self-service reporting and writeback capabilities. By integrating with leading cloud data warehouses like Snowflake and BigQuery, Astrato aims to enhance data accessibility and foster data adoption across organizations. Founded by the team behind Vizlib, the company leverages deep expertise in business intelligence and intuitive design to provide fast, effective, and personalized analytics solutions for users seeking to uncover meaningful insights.

Corsmed

Seed Round in 2024
Corsmed AB, founded in 2016 and based in Lund, Sweden, specializes in developing advanced cloud infrastructures for medical imaging applications, particularly focusing on magnetic resonance imaging (MRI). The company is known for its innovative MRI simulation platform, often likened to a “flight simulator of MRI,” which serves as an educational tool for current and future MRI operators. This platform allows users, including medical professionals, students, and educators, to practice on virtual MRI scanners, enhancing their skills in a safe environment. Additionally, it provides a research module that enables users to build and test pulse sequences on anatomical models without needing access to a physical MRI scanner. Through these offerings, Corsmed aims to improve the training and capabilities of medical personnel globally.

Navenio

Series A in 2023
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Dyania Health

Seed Round in 2022
Dyania Health focuses on enhancing clinical research efficiency through its proprietary Synapsis AI platform. This technology automates manual chart reviews, a traditionally labor-intensive process in healthcare, allowing clinicians to provide timely and effective patient care. Dyania's system is utilized by large healthcare organizations to facilitate enterprise-wide clinical trial pre-screening, conduct automated chart reviews for observational studies, and streamline complex registry reporting. By leveraging artificial intelligence and machine learning to analyze unstructured electronic medical record data, Dyania Health significantly reduces manual workloads, improves the accuracy of clinical research, and enhances the identification of potential candidates for clinical drug trials.

OrthoSon

Series A in 2022
OrthoSon Limited is a medical device company based in Oxford, United Kingdom, focused on developing a minimally-invasive treatment for chronic low back pain. Established in 2015, the company has created a novel bio-structural gel implant that is injected into the nucleus of the intervertebral disc. This innovative procedure follows the natural fissures of degeneration, allowing the gel to restore the disc's mechanical function and alleviate pain. By providing a motion-preserving alternative to traditional spinal fusion techniques, OrthoSon aims to offer patients a safe and effective option that takes less than 30 minutes and does not require incisions.

Cylinder

Series A in 2022
Founded in 2021, Cylinder delivers personalized, clinician-backed care to those suffering from digestive issues through its virtual health platform and has helped nearly 100K members to date. Cylinder's platform offers dynamically updated content and care plans designed to improve engagement and outcomes. Members enjoy access to a dedicated care team nationwide, including health coaches, registered dietitians, and GI doctors. Cylinder’s vision is to create a world where people receive convenient, personalized, and affordable access to the quality digestive health care they need to improve their overall health. Trusted by businesses including Texas A&M University, US Foods, and more, Cylinder showcases up to 5:1 ROI and an average of 13% employee engagement. Learn more at cylinderhealth.com.

Navenio

Venture Round in 2021
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Intelligencia AI

Series A in 2021
Intelligencia is an enterprise SaaS company that applies Machine Learning to assess and mitigate the risk in clinical development strategy/design.

Anodyne Nanotech

Seed Round in 2021
Anodyne Nanotech is a preclinical-stage biotechnology firm that focuses on developing innovative transdermal drug delivery systems. Founded in 2019 by Jake Lombardo, Konstantinos Tzortzakis, and Hojatollah Rezaei Nejad, the company has created a platform known as Hero Patch. This technology utilizes porous microneedles to deliver clinically significant doses of macromolecules, such as monoclonal antibodies and small molecules, in a cost-effective manner. Anodyne's approach aims to simplify the administration of medications for chronic diseases, providing healthcare professionals with efficient alternatives to traditional injection methods.

Bryq

Seed Round in 2020
Bryq is a Talent Intelligence platform that utilizes validated psychometrics to enhance the hiring process for companies. By offering a scientifically based talent assessment, Bryq helps organizations identify diverse and suitable candidates by matching their skills and personality traits to specific job and company requirements. The platform employs customizable indicators that provide insights into candidates' leadership qualities and innovation potential, effectively promoting a culture of diversity within teams. By moving beyond traditional resumes and unstructured interviews, Bryq aims to streamline recruitment and foster a more meaningful hiring experience, ultimately contributing to a positive organizational culture.

TileDB

Series A in 2020
TileDB, Inc. develops and maintains a system for managing multi-dimensional array data, particularly suited for scientific applications. The company's offerings include TileDB Embedded, a storage engine, and TileDB Cloud, which facilitates the management of array data in the cloud. Designed to handle a variety of data types, including unstructured multimodal data, TileDB addresses the complexities encountered in fields such as genomics, biomedical imaging, and multiomic data analysis. This foundational software is utilized by research teams in pharmaceuticals and biotechnology to enhance their data platforms and drive scientific discovery. Founded in 2017 and headquartered in Cambridge, Massachusetts, TileDB also has a location in Athens, Greece.

Navenio

Series A in 2020
Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Athroa Innovations

Seed Round in 2019
Athroa Innovations, founded in 2019 and based in Athens, Greece, specializes in commercializing deep science inventions through the licensing of intellectual property (IP). The company provides innovators with an alternative to launching start-ups by facilitating IP licensing, allowing them to concentrate on advancing their core research. Athroa Innovations also offers a competitive advantage in prototyping, leveraging Greece's resources to support innovators. In addition to its licensing model, the company engages in venture building and invests in sectors such as health technology, clean technology, and food technology.

Accusonus

Series A in 2019
Accusonus, Inc. is a software development company specializing in tools for the professional music sector and consumer electronics. Founded in 2012 by Alexandros Tsilfidis and Elias Kokkinis, the company aims to advance audio technologies to enhance the global digital audio and speech technology market. Its flagship products include drumatom, which reduces drum bleed, and drumatom player for leakage suppression. Additionally, it offers ERA-D for sound processing and Regroover, an AI-based beat machine for music sampling. The company also creates embedded software for speech enhancement. Headquartered in Lexington, Massachusetts, Accusonus maintains operations in Patras and Athens, Greece, including a professional recording studio for acoustic testing. The team comprises skilled engineers and scientists dedicated to improving audio quality and accessibility for music professionals.

TileDB

Seed Round in 2019
TileDB, Inc. develops and maintains a system for managing multi-dimensional array data, particularly suited for scientific applications. The company's offerings include TileDB Embedded, a storage engine, and TileDB Cloud, which facilitates the management of array data in the cloud. Designed to handle a variety of data types, including unstructured multimodal data, TileDB addresses the complexities encountered in fields such as genomics, biomedical imaging, and multiomic data analysis. This foundational software is utilized by research teams in pharmaceuticals and biotechnology to enhance their data platforms and drive scientific discovery. Founded in 2017 and headquartered in Cambridge, Massachusetts, TileDB also has a location in Athens, Greece.

Intelligencia AI

Seed Round in 2018
Intelligencia is an enterprise SaaS company that applies Machine Learning to assess and mitigate the risk in clinical development strategy/design.

Fieldscale

Series A in 2018
Fieldscale is a company based in Thessaloniki, Greece, that specializes in developing cloud-based simulation software for the touch sensor industry. Its flagship product, SENSE, provides advanced capacitive touch sensor simulation capabilities, enabling engineers to conduct electric design and analysis with enhanced accuracy and efficiency. The software employs sophisticated algorithms within an intuitive user interface, allowing for the execution of complex simulations, including electric field analysis and assessments of dielectric breakdowns and partial discharges. By facilitating thousands of analyses and various scenarios within a single day, Fieldscale empowers engineers to optimize sensor designs while reducing power consumption, thereby improving the overall design process for touchscreen products. Founded in 2015, the company aims to provide solutions that help users achieve optimal design outcomes more quickly than their competitors.

Balena

Funding Round in 2018
Balena Inc. operates a platform that provides comprehensive tools for building, deploying, and managing fleets of connected Internet of Things (IoT) devices. The company offers a range of products, including balenaCloud, balenaOS, balenaFin, balenaEngine, balenaEtcher, and openbalena, which facilitate application development, device deployment, and management for fleet owners. Balena's infrastructure enables developers to focus on application growth while managing, monitoring, and updating devices through a web dashboard, API, CLI, and SDK. The platform supports Linux containers and open technologies, allowing for seamless firmware deployment and compatibility with various programming languages and libraries. Founded in 2013 and based in Seattle, Washington, Balena also has offices in Greece and the United Kingdom. The company was previously known as Resin, Inc. until its rebranding in October 2018.
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