Big Pi Ventures

Founded in Athens, Greece, Big Pi Ventures is a venture capital firm investing globally with a focus on early-stage technology companies. They prioritize innovative solutions in sectors such as computer science, artificial intelligence, life sciences, and climate technologies. The firm invests amounts ranging from USD 0.5 million to USD 3 million.

Aristos Doxiadis

Partner

Alex Eleftheriadis

Partner

Achilleas Gravanis

Venture Partner

Cassandra Kosmidou

Investment Associate

Melina Mai

Technology Investment Associate

Hector Matsaganis

Analyst

Marco Veremis

Partner

20 past transactions

Astrato Analytics

Seed Round in 2025
Astrato offers a cloud-native business intelligence platform that enables organizations to build, explore, and share real-time data insights. It provides advanced dashboarding, self-service reporting, and writeback capabilities on top of leading cloud data warehouses like Snowflake and BigQuery.

Corsmed

Seed Round in 2024
Founded in 2016, Corsmed specializes in developing advanced cloud-based platforms for medical imaging education. Its flagship product is a highly realistic Magnetic Resonance Imaging (MRI) simulation platform, often referred to as 'the flight simulator of MRI'. This platform enables educational institutions, healthcare providers, and research organizations worldwide to enhance MRI-related skills, improve patient safety, and facilitate innovative research.

Navenio

Series A in 2023
Navenio Limited is a software technology company based in Oxford, United Kingdom, specializing in location-based services for indoor environments through mobile applications. Established in 2015, Navenio's innovative platform enhances indoor localization without the need for additional hardware, such as beacons or Wi-Fi. By utilizing advanced techniques like fingerprinting of the electromagnetic spectrum and indoor mapping, Navenio's solutions enable clients across various sectors, including retail, transportation, venues, and healthcare, to efficiently locate individuals and improve workforce productivity. The company's intelligent workforce solution automates processes based on established best practices, leading to significant enhancements in staff efficiency and operational workflows.

Dyania Health

Seed Round in 2022
Dyania Health develops and deploys an AI-powered platform called Synapsis AI that automates manual chart review, a time-consuming task in modern healthcare, enabling clinicians to deliver optimal care when patients need it. The platform is used by large healthcare systems to enable enterprise-wide clinical trial pre-screening, automate chart review for observational studies, and automate complex registry reporting, reducing manual workloads and improving accuracy and timeliness. By analyzing unstructured electronic medical record data with artificial intelligence and machine learning, Dyania Health helps identify potential candidates for clinical drug trials, enhancing productivity and efficiency of clinical research teams.

Bryq

Seed Round in 2022
Bryq, established in 2014, is a talent assessment platform headquartered in Nicosia, Cyprus, with offices in London and Athens. It specializes in bias-free hiring, pre-employment assessments, and internal mobility. Bryq's platform leverages validated psychometrics to help employers diversify their teams and build organizational culture. By identifying leadership qualities and innovation potential in candidates, Bryq's customizable 'Indicators' provide insights to enhance the hiring process, reducing time to hire and promoting cultural fit.

OrthoSon

Series A in 2022
OrthoSon develops a minimally invasive, incision-free, motion-preserving medical device for chronic low back pain. The core technology is an injectable bio-structural gel implant delivered into the nucleus pulposus of the degenerating intervertebral disc, where it gels to support mechanical function and slow degeneration, aiming to provide a micro-invasive alternative to spinal fusion. The system seeks to restore spine function and alleviate discogenic pain, targeting patients with persistent back pain. The company was incorporated in 2015 and is based in Oxford, United Kingdom.

Cylinder

Series A in 2022
Vivante Health, Inc. is a digital health company focused on addressing digestive health and chronic conditions. Founded in 2016, it has developed GIThrive, a technology platform designed to provide actionable insights for managing digestive issues. GIThrive offers a comprehensive digital gut health program that includes expert guidance, 24/7 support, and personalized care plans. The company also provides GIMate, an innovative portable breathalyzer that identifies trigger foods, and GutCheck, which analyzes gut bacteria to recommend tailored diets. Vivante Health emphasizes individualized care, utilizing a scalable platform that integrates real-time data from biometric devices and partners. This approach not only aims to reduce healthcare costs and improve employee health for large employers and health plans but also enhances user empowerment through advanced science and technology. Headquartered in Houston, Texas, with an additional office in Athens, Greece, Vivante Health continues to prioritize innovative solutions in the realm of digestive health.

Navenio

Venture Round in 2021
Navenio Limited is a software technology company based in Oxford, United Kingdom, specializing in location-based services for indoor environments through mobile applications. Established in 2015, Navenio's innovative platform enhances indoor localization without the need for additional hardware, such as beacons or Wi-Fi. By utilizing advanced techniques like fingerprinting of the electromagnetic spectrum and indoor mapping, Navenio's solutions enable clients across various sectors, including retail, transportation, venues, and healthcare, to efficiently locate individuals and improve workforce productivity. The company's intelligent workforce solution automates processes based on established best practices, leading to significant enhancements in staff efficiency and operational workflows.

Intelligencia AI

Series A in 2021
Intelligencia AI is an enterprise SaaS company that specializes in applying machine learning technology to enhance clinical development strategies. The company has developed a cloud-based platform that utilizes predictive analytics to assess, quantify, and mitigate risks associated with clinical trials. By estimating the probability of success for various trial designs, Intelligencia's platform allows healthcare organizations to optimize their approaches before initiating trials. This proactive risk management not only helps to save time and resources for clinical trials but also facilitates quicker access to innovative therapies for patients.

Anodyne Nanotech

Seed Round in 2021
Anodyne Nanotech is a preclinical-stage biotechnology company founded in 2019 by Jake Lombardo, Konstantinos Tzortzakis, and Hojatollah Rezaei Nejad. The company specializes in developing innovative transdermal delivery systems for high-value drugs, utilizing a proprietary porous microneedle technology. Their flagship product, the Hero Patch, is designed to deliver clinically significant doses of macromolecules, including monoclonal antibodies and small molecules, in a practical and cost-effective manner. This technology aims to simplify chronic disease management by providing healthcare professionals with a reliable alternative to traditional injections, facilitating fast and sustained drug delivery.

Altered

Seed Round in 2020
Altered is an AI-powered audio platform that provides a next-generation editor and voice content creation tools. The platform integrates multiple voice AI technologies into a single, user-friendly application to produce high-quality voice content, including voice cloning, voice morphing, and services for recording. It enables changes to vocal identity, accent, and performance style while preserving delivery tempo, inflection, and tonality, allowing creators and professionals to craft professional voice performances. The company aims to democratize digital audio by making advanced AI capabilities accessible to a broad audience.

Bryq

Seed Round in 2020
Bryq, established in 2014, is a talent assessment platform headquartered in Nicosia, Cyprus, with offices in London and Athens. It specializes in bias-free hiring, pre-employment assessments, and internal mobility. Bryq's platform leverages validated psychometrics to help employers diversify their teams and build organizational culture. By identifying leadership qualities and innovation potential in candidates, Bryq's customizable 'Indicators' provide insights to enhance the hiring process, reducing time to hire and promoting cultural fit.

TileDB

Series A in 2020
TileDB, Inc. is a technology company specializing in the management of multi-dimensional array data, primarily for scientific applications. Founded in 2017 and headquartered in Cambridge, Massachusetts, with an additional location in Athens, Greece, TileDB offers a cloud-based storage platform and embedded storage engine. Its innovative software is designed to handle diverse data types, including unstructured and multimodal data, making it suitable for complex scientific inquiries such as genomic research and biomedical imaging. TileDB enables users to access, analyze, and share intricate datasets effectively, supporting scientific teams in pharmaceutical and biotechnology sectors to advance drug discovery and other research initiatives. Through its robust platform, TileDB facilitates parallel data analytics and integrates various dimensions and attributes within data arrays, positioning itself as a critical tool for scientific breakthroughs.

Navenio

Series A in 2020
Navenio Limited is a software technology company based in Oxford, United Kingdom, specializing in location-based services for indoor environments through mobile applications. Established in 2015, Navenio's innovative platform enhances indoor localization without the need for additional hardware, such as beacons or Wi-Fi. By utilizing advanced techniques like fingerprinting of the electromagnetic spectrum and indoor mapping, Navenio's solutions enable clients across various sectors, including retail, transportation, venues, and healthcare, to efficiently locate individuals and improve workforce productivity. The company's intelligent workforce solution automates processes based on established best practices, leading to significant enhancements in staff efficiency and operational workflows.

Athroa Innovations

Seed Round in 2019
Athroa Innovations is a company based in Athens, Greece, founded in 2019, that specializes in the commercialization of deep science inventions through the licensing of intellectual property (IP). It provides innovators with the opportunity to license their IP as an alternative to launching a startup, allowing them to concentrate on advancing their core research. The company also offers advantages such as the ability to conduct prototyping in Greece, which can enhance the development process. Athroa Innovations is actively involved in sectors such as health technology, clean technology, and food technology, positioning itself as a key player in fostering innovation in these fields.

Accusonus

Series A in 2019
Founded in 2012, Accusonus specializes in developing innovative software tools for professional audio processing. Headquartered in Lexington, Massachusetts with operations in Patras, Greece, the company offers products like drumatom (for reducing drum bleed), ERA-D (for sound processing), and Regroover (an AI-powered beat machine). They also develop embedded speech enhancement solutions for consumer electronics. Accusonus' patented Machine Learning and Artificial Intelligence technology drives its sound processing workflows.

TileDB

Seed Round in 2019
TileDB, Inc. is a technology company specializing in the management of multi-dimensional array data, primarily for scientific applications. Founded in 2017 and headquartered in Cambridge, Massachusetts, with an additional location in Athens, Greece, TileDB offers a cloud-based storage platform and embedded storage engine. Its innovative software is designed to handle diverse data types, including unstructured and multimodal data, making it suitable for complex scientific inquiries such as genomic research and biomedical imaging. TileDB enables users to access, analyze, and share intricate datasets effectively, supporting scientific teams in pharmaceutical and biotechnology sectors to advance drug discovery and other research initiatives. Through its robust platform, TileDB facilitates parallel data analytics and integrates various dimensions and attributes within data arrays, positioning itself as a critical tool for scientific breakthroughs.

Intelligencia AI

Seed Round in 2018
Intelligencia AI is an enterprise SaaS company that specializes in applying machine learning technology to enhance clinical development strategies. The company has developed a cloud-based platform that utilizes predictive analytics to assess, quantify, and mitigate risks associated with clinical trials. By estimating the probability of success for various trial designs, Intelligencia's platform allows healthcare organizations to optimize their approaches before initiating trials. This proactive risk management not only helps to save time and resources for clinical trials but also facilitates quicker access to innovative therapies for patients.

Fieldscale

Series A in 2018
Fieldscale is a company based in Thessaloniki, Greece, specializing in the development of simulation software solutions for the touch sensor industry. Founded in 2015, Fieldscale offers SENSE, a cloud-based platform that provides advanced capacitive touch sensor simulation for electric design and analysis. The software incorporates sophisticated algorithms within an intuitive user interface, allowing engineers to perform electric field analyses and optimize sensor designs efficiently. It enables the detection of dielectric breakdowns, partial discharges, and assessments of lightning strike phenomena. By facilitating thousands of analyses and various scenarios within a single day, Fieldscale empowers engineers to enhance their designs while reducing power consumption, ultimately leading to faster and more effective product development.

Balena

Funding Round in 2018
Balena is a technology company that provides a complete set of tools and infrastructure for building, deploying, and managing fleets of connected IoT devices. Its platform enables fleet owners to develop applications, deploy firmware using Linux containers and open technologies, provision devices, collect logs, and perform cross-compilation, while supporting any Linux-supported language, library, and API on embedded products. Devices and their services can be managed, monitored, and updated through a web dashboard, API, CLI, or SDK. The platform is used across industries such as connected homes, manufacturing, logistics, marketing, and retail. Balena was established in 2013 and is headquartered in Seattle, with additional offices in Greece and the United Kingdom.
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