BioStar Capital

Nectero Medical is a clinical-stage biotechnology company based in Dover, Delaware, founded in 2017. The company is focused on developing a novel treatment aimed at stabilizing the growth of mid-sized abdominal aortic aneurysms and preventing their rupture. Nectero Medical's innovative approach involves delivering a compound with a stabilizing agent directly to the aneurysm site, which inhibits further breakdown of the vessel wall and strengthens it. This treatment enables patients to undergo earlier intervention safely, potentially delaying or eliminating the need for major endovascular or surgical repairs.

MMI S.r.l. is an Italian company that specializes in the manufacture and development of advanced micro instruments designed for surgical interventions. Founded in 2015 and based in Calci, Italy, MMI focuses on creating wristed micro instruments and their associated fabrication processes. The company also offers a proprietary robotic platform that enhances the capabilities of these instruments, facilitating complex reconstruction procedures following traumatic injuries and tumor removals in areas such as the breast, head, and bones. MMI aims to support surgeons globally by providing innovative tools that improve surgical outcomes while also reducing costs for patients and healthcare systems.

Amplitude Vascular Systems is a medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2020 and is based in Ann Arbor, Michigan.

Amplitude Vascular Systems is a medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2020 and is based in Ann Arbor, Michigan.

Amplitude Vascular Systems is a medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2020 and is based in Ann Arbor, Michigan.

REVA Medical, Inc. is a medical device company based in San Diego, California, established in 1998. The company specializes in developing and commercializing polymer-based bioresorbable products for vascular applications. Its primary offerings include the Fantom Encore, a bioresorbable vascular scaffold designed for the treatment of coronary artery disease, and the MOTIV scaffold for below-the-knee peripheral artery disease. REVA Medical's products utilize proprietary tyrosine-derived polymer technologies that support the healing of arteries while eventually dissolving in the body, thus restoring natural function. The Fantom Encore is marketed in several European countries, including Germany, Switzerland, and Italy. Initially founded as MD3, Inc., the company rebranded to REVA Medical, Inc. in March 2002.

MMI S.r.l. is an Italian company that specializes in the manufacture and development of advanced micro instruments designed for surgical interventions. Founded in 2015 and based in Calci, Italy, MMI focuses on creating wristed micro instruments and their associated fabrication processes. The company also offers a proprietary robotic platform that enhances the capabilities of these instruments, facilitating complex reconstruction procedures following traumatic injuries and tumor removals in areas such as the breast, head, and bones. MMI aims to support surgeons globally by providing innovative tools that improve surgical outcomes while also reducing costs for patients and healthcare systems.

Founded in 2011 and headquartered in San Jose, California with an additional office in Kalamazoo, Michigan, Ablative Solutions is a medical device company specializing in the development of catheters for treating hypertension. Its flagship product, the Peregrine System, enables minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels.

Founded in 2013, Foldax designs and manufactures synthetic heart valves using life polymer technology. Its products aim to provide artificial blood pumping support for patients with aortic, mitral, or tricuspid valve disease via percutaneous or surgical delivery.

Aria CV, Inc. is a medical device company based in St. Paul, Minnesota, specializing in treatments for pulmonary arterial hypertension (PAH). Founded in 2010 by Drs. John Scandurra and Karl Vollmers, the company has developed an innovative implantable cardiovascular device aimed at reducing the workload on the right side of the heart. This device holds the potential to enhance both the survival and quality of life for patients suffering from pulmonary hypertension. Aria CV has secured an exclusive license for certain patents from the University of Minnesota, reflecting its commitment to advancing medical technology in this critical area of healthcare.

Corindus Vascular Robotics, Inc. specializes in the design, manufacture, and commercialization of robotic-assisted systems for interventional vascular procedures. Based in Waltham, Massachusetts, the company offers the CorPath system, which allows physicians to perform catheterization procedures from a radiation-shielded control console, enhancing precision and safety in coronary and peripheral interventions. The CorPath GRX system further enables the robotic-assisted control of guide catheters, guidewires, and balloon/stent devices. Corindus serves various markets, including vascular, coronary, neurointerventional, and structural heart fields, selling its products through a combination of direct sales and partnerships. Founded in 2002, Corindus is a subsidiary of Siemens Medical Solutions USA, Inc. as of late 2019.

Trice Medical develops orthopedic diagnostic devices featuring integrated camera-enabled technologies. These devices enable minimally invasive procedures in office settings, providing painless, cosmetically undetectable care while maintaining surgical grade standards.

Founded in 2011 and headquartered in San Jose, California with an additional office in Kalamazoo, Michigan, Ablative Solutions is a medical device company specializing in the development of catheters for treating hypertension. Its flagship product, the Peregrine System, enables minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels.

V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

Corindus Vascular Robotics, Inc. specializes in the design, manufacture, and commercialization of robotic-assisted systems for interventional vascular procedures. Based in Waltham, Massachusetts, the company offers the CorPath system, which allows physicians to perform catheterization procedures from a radiation-shielded control console, enhancing precision and safety in coronary and peripheral interventions. The CorPath GRX system further enables the robotic-assisted control of guide catheters, guidewires, and balloon/stent devices. Corindus serves various markets, including vascular, coronary, neurointerventional, and structural heart fields, selling its products through a combination of direct sales and partnerships. Founded in 2002, Corindus is a subsidiary of Siemens Medical Solutions USA, Inc. as of late 2019.

CathWorks is a medical technology company that applies computational science platforms to enhance percutaneous coronary intervention (PCI) therapy decisions. It offers CathWorks FFRangio, a non-invasive device delivering objective multi-vessel physiologic measurements to optimize and confirm intra-procedural PCI therapies.

Trice Medical develops orthopedic diagnostic devices featuring integrated camera-enabled technologies. These devices enable minimally invasive procedures in office settings, providing painless, cosmetically undetectable care while maintaining surgical grade standards.

Corindus Vascular Robotics, Inc. specializes in the design, manufacture, and commercialization of robotic-assisted systems for interventional vascular procedures. Based in Waltham, Massachusetts, the company offers the CorPath system, which allows physicians to perform catheterization procedures from a radiation-shielded control console, enhancing precision and safety in coronary and peripheral interventions. The CorPath GRX system further enables the robotic-assisted control of guide catheters, guidewires, and balloon/stent devices. Corindus serves various markets, including vascular, coronary, neurointerventional, and structural heart fields, selling its products through a combination of direct sales and partnerships. Founded in 2002, Corindus is a subsidiary of Siemens Medical Solutions USA, Inc. as of late 2019.

TransMedics Group, Inc., established in 1998 and based in Andover, Massachusetts, is a commercial-stage medical technology company specializing in transforming organ transplant therapy for end-stage organ failure patients worldwide. The company's core product, the Organ Care System (OCS), is a portable, innovative technology that maintains donor organs outside the body in a near-physiologic state, replicating human-like conditions. This system includes OCS LUNG and OCS Heart, designed to preserve and optimize lungs and hearts respectively during transport, allowing for better assessment and improvement of organ condition. TransMedics also offers clinical services to enhance transplant volume, improve outcomes, and reduce learning curves for healthcare providers.

TransMedics Group, Inc., established in 1998 and based in Andover, Massachusetts, is a commercial-stage medical technology company specializing in transforming organ transplant therapy for end-stage organ failure patients worldwide. The company's core product, the Organ Care System (OCS), is a portable, innovative technology that maintains donor organs outside the body in a near-physiologic state, replicating human-like conditions. This system includes OCS LUNG and OCS Heart, designed to preserve and optimize lungs and hearts respectively during transport, allowing for better assessment and improvement of organ condition. TransMedics also offers clinical services to enhance transplant volume, improve outcomes, and reduce learning curves for healthcare providers.

V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

Kona Medical, Inc. is a medical technology company that specializes in developing a non-invasive ultrasound-based therapy system aimed at treating hypertension and related disorders. Established in 2009 by Dr. Michael Gertner, the company focuses on addressing the challenges posed by drug-resistant hypertension through innovative approaches, particularly renal artery denervation. Its flagship product, Surround Sound, employs ultrasound imaging to precisely guide the delivery of focused ultrasound energy for renal denervation, offering a less invasive alternative to traditional treatments. Based in Issaquah, Washington, Kona Medical integrates Dr. Gertner's inventions with assets from Therus Corporation, enhancing its capabilities in therapeutic focused ultrasound.

Aria CV, Inc. is a medical device company based in St. Paul, Minnesota, specializing in treatments for pulmonary arterial hypertension (PAH). Founded in 2010 by Drs. John Scandurra and Karl Vollmers, the company has developed an innovative implantable cardiovascular device aimed at reducing the workload on the right side of the heart. This device holds the potential to enhance both the survival and quality of life for patients suffering from pulmonary hypertension. Aria CV has secured an exclusive license for certain patents from the University of Minnesota, reflecting its commitment to advancing medical technology in this critical area of healthcare.

Trice Medical develops orthopedic diagnostic devices featuring integrated camera-enabled technologies. These devices enable minimally invasive procedures in office settings, providing painless, cosmetically undetectable care while maintaining surgical grade standards.

Conventus Orthopaedics offers orthopedic and sports medicine services, including surgery, reconstructive procedures, spine surgery, joint replacement, sports medicine, physical therapy, and fracture care. Founded by medical professionals in 2009, the company focuses on less invasive treatments for complex periarticular fractures. It employs advanced nitinol technology to create a platform that delivers robust fixation and reliable repairs. The practice is located in Maple Grove, Minnesota.

VytronUS, Inc. is a manufacturer of cardiac medical devices, specializing in solutions for treating cardiac arrhythmia. Founded in 2006 and based in Sunnyvale, California, the company develops innovative technologies that leverage ultrasound energy for both imaging and therapeutic purposes. Its devices facilitate precise, non-contact energy delivery and create high-resolution maps of cardiac anatomy, empowering physicians to address complex arrhythmias with enhanced visualization and precision. VytronUS's focus on automation and flexibility in its device offerings positions it as a key player in the cardiac medical device market.

Trice Medical develops orthopedic diagnostic devices featuring integrated camera-enabled technologies. These devices enable minimally invasive procedures in office settings, providing painless, cosmetically undetectable care while maintaining surgical grade standards.

Domain Surgical is a medical device company that is creating energy-based surgical products for precise soft tissue cutting and coagulation. It creates energy-based equipment used in specialty surgical procedures. Its patent-pending technology produces surface-only tissue effects with energy that does not pass through the patient designed with the surgical staff in mind, for simple user-interface and training. The company manufactures and markets the FMwand Ferromagnetic Surgical System, a hemostatic dissection device that uses pure thermal energy to cut and coagulate soft tissue, without passing an electrical current through the patient. The FMwand imparts as little as 1/10th the amount of thermal injury compared to traditional electrosurgery devices. The FMwand provides fine dissection with a layer-by-layer precision that is unmatched by existing surgical technology.

Founded in 2011 and headquartered in San Jose, California with an additional office in Kalamazoo, Michigan, Ablative Solutions is a medical device company specializing in the development of catheters for treating hypertension. Its flagship product, the Peregrine System, enables minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels.

Trice Orthopedics, Inc., headquartered in King of Prussia, Pennsylvania, specializes in developing camera-enabled needle technology for orthopedic diagnostic and therapeutic procedures. The company aims to enhance the quality of patient care by facilitating instant and accurate office-based procedures. By integrating miniaturized opto-electronics into its clinical solutions, Trice's innovations provide more immediate and definitive results compared to traditional methods, which often yield false readings. This approach not only benefits patients and physicians by streamlining the diagnostic process but also aims to reduce healthcare costs through the utilization of existing reimbursement codes.

Trice Medical develops orthopedic diagnostic devices featuring integrated camera-enabled technologies. These devices enable minimally invasive procedures in office settings, providing painless, cosmetically undetectable care while maintaining surgical grade standards.

Angioslide, Ltd. is a medical device company established in 2005 and headquartered in Natanya, Israel, with additional subsidiaries in Karlsruhe, Germany, and Edina, Minnesota. The company specializes in developing innovative angioplasty products, notably the Angioslide eXtra balloon catheter, which serves both as a stand-alone balloon for angioplasty and as a device for debris removal. Its proprietary Embolic Capture Angioplasty™ technology allows physicians to capture and eliminate embolic particles, chronic thrombus, and atherosclerotic plaque debris during angioplasty procedures. Angioslide focuses on addressing the needs of various markets, including peripheral artery, lower limb artery, carotid, and coronary artery diseases.

Kona Medical, Inc. is a medical technology company that specializes in developing a non-invasive ultrasound-based therapy system aimed at treating hypertension and related disorders. Established in 2009 by Dr. Michael Gertner, the company focuses on addressing the challenges posed by drug-resistant hypertension through innovative approaches, particularly renal artery denervation. Its flagship product, Surround Sound, employs ultrasound imaging to precisely guide the delivery of focused ultrasound energy for renal denervation, offering a less invasive alternative to traditional treatments. Based in Issaquah, Washington, Kona Medical integrates Dr. Gertner's inventions with assets from Therus Corporation, enhancing its capabilities in therapeutic focused ultrasound.

Founded in 2011 and headquartered in San Jose, California with an additional office in Kalamazoo, Michigan, Ablative Solutions is a medical device company specializing in the development of catheters for treating hypertension. Its flagship product, the Peregrine System, enables minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels.

Kona Medical, Inc. is a medical technology company that specializes in developing a non-invasive ultrasound-based therapy system aimed at treating hypertension and related disorders. Established in 2009 by Dr. Michael Gertner, the company focuses on addressing the challenges posed by drug-resistant hypertension through innovative approaches, particularly renal artery denervation. Its flagship product, Surround Sound, employs ultrasound imaging to precisely guide the delivery of focused ultrasound energy for renal denervation, offering a less invasive alternative to traditional treatments. Based in Issaquah, Washington, Kona Medical integrates Dr. Gertner's inventions with assets from Therus Corporation, enhancing its capabilities in therapeutic focused ultrasound.

CV Ingenuity, a Palo Alto, CA-based medical device company. CV Ingenuity Corp., a medical device company, develops devices for the treatment of vascular diseases to relieve vascular obstructions, inhibit restenosis, and allow natural vessel healing. It offers Drug Coated Balloon platform for the "Touch-and-Go" treatment of vascular disease. It was incorporated in 2008 and is based in Fremont, California. As of January 10, 2013, CV Ingenuity Corp. operates as a subsidiary of Covidien plc.

Ellipse Technologies is a privately-held medical device company based in California that specializes in the development of implantable remote control technology for spinal and orthopedic applications. The company designs and commercializes innovative devices aimed at treating a wide range of spinal deformities and orthopedic trauma, including fracture management. Its flagship products, the MAGEC MAGnetic Expansion Control System and the PRECICE System, utilize advanced, non-invasive technologies that allow for remote adjustments by physicians through an external magnetic field. These devices are designed to restore proper anatomical position and alignment, improving patient outcomes in the management of spinal and long-bone abnormalities.

Reverse Medical is a commercial-stage medical device company dedicated to the development of innovative solutions for neurovascular disorders, particularly in the management of acute ischemic strokes. The company specializes in creating embolic protection systems designed to enhance the revascularization process for patients experiencing these critical conditions. By concentrating on endovascular treatment options, Reverse Medical aims to improve patient outcomes and streamline interventions for stroke care, positioning itself as a key player in the medical technology sector.

Embrella Cardiovascular, Inc. is a company based in Malvern, Pennsylvania, focused on developing innovative systems for embolic cerebral protection. Its primary goal is to assist interventionalists in minimizing the incidence of embolic strokes that can occur during cardiovascular procedures. By enhancing the safety and effectiveness of these interventions, Embrella Cardiovascular aims to improve patient outcomes and advance the field of cardiovascular medicine.

Revascular Therapeutics is a medical device company that develops solutions for the intravascular treatment of complex lesions and total occlusions. Revascular develops percutaneous medical devices to reopen occluded vessels.

SynergEyes, Inc. is a technology-driven company specializing in the development and manufacturing of hybrid contact lenses designed to enhance vision and improve quality of life for patients. Founded in 2001 and headquartered in Carlsbad, California, SynergEyes offers innovative products that combine the visual acuity of rigid gas permeable lenses with the comfort of soft lenses. Their hybrid lenses cater to a range of eye conditions, including astigmatism, presbyopia, myopia, hyperopia, and keratoconus, utilizing advanced high-Dk materials and vision-optimized designs. The company distributes its products both domestically and internationally, emphasizing a commitment to improving eye health and transforming vision for eye care professionals and their patients.

Corindus Vascular Robotics, Inc. specializes in the design, manufacture, and commercialization of robotic-assisted systems for interventional vascular procedures. Based in Waltham, Massachusetts, the company offers the CorPath system, which allows physicians to perform catheterization procedures from a radiation-shielded control console, enhancing precision and safety in coronary and peripheral interventions. The CorPath GRX system further enables the robotic-assisted control of guide catheters, guidewires, and balloon/stent devices. Corindus serves various markets, including vascular, coronary, neurointerventional, and structural heart fields, selling its products through a combination of direct sales and partnerships. Founded in 2002, Corindus is a subsidiary of Siemens Medical Solutions USA, Inc. as of late 2019.

AorTx, Inc. develops device solutions for percutaneous replacement of the aortic valve in the United States. Its devices cover the procedural solution for heart valve therapy from the implant to delivery and deployment of the valve. AorTx, Inc. was formerly known as CardiacMD, Inc. The company is based in Redwood City, California. As of November 15, 2007, AorTx, Inc. operates as a subsidiary of Hansen Medical, Inc.

Avantis Medical Systems, Inc. is a medical device company based in Sunnyvale, California, focused on developing and manufacturing catheter-based endoscopic devices. The company aims to enhance the detection and treatment of cancers and other abnormalities within the gastrointestinal (GI) tract. Leveraging decades of experience in the medical device industry, Avantis is creating innovative solutions that integrate advanced technologies, such as micro-chips and reinforced catheters. Their offerings are designed to provide safe, effective, and cost-efficient healthcare services, ultimately enhancing patient outcomes and recovery times.

Pynk is an investment platform that harnesses the power of Artificial Intelligence to leverage the Wisdom IN Crowds™, allowing users to make informed investment decisions. The company aggregates predictions and forecasts from a global community of contributors across more than 185 countries, utilizing machine learning to analyze market data effectively. Founded in 2018 by experienced entrepreneurs Seth Ward, Rupert Barksfield, and Mark Little, Pynk aims to democratize wealth management by combining crowd-sourced insights with expert analysis. The platform empowers investors to mitigate risks and potentially achieve superior returns. Pynk is supported by notable financial institutions, including RBS and Natwest banks in the UK, and has successfully raised $2 million in pre-seed and seed funding to date.

Broncus Technologies is a medical technology company specializing in minimally-invasive devices for treating emphysema and other lung diseases. Its flagship product, Exhale, employs Airway Bypass therapy, potentially the first minimally-invasive treatment for severe homogeneous emphysema. Broncus is currently enrolling patients worldwide in its pivotal EASE Trial.

Avantis Medical Systems, Inc. is a medical device company based in Sunnyvale, California, focused on developing and manufacturing catheter-based endoscopic devices. The company aims to enhance the detection and treatment of cancers and other abnormalities within the gastrointestinal (GI) tract. Leveraging decades of experience in the medical device industry, Avantis is creating innovative solutions that integrate advanced technologies, such as micro-chips and reinforced catheters. Their offerings are designed to provide safe, effective, and cost-efficient healthcare services, ultimately enhancing patient outcomes and recovery times.