BioStar Capital

Nectero Medical is a clinical-stage biotechnology company based in Dover, Delaware, that focuses on treating mid-sized abdominal aortic aneurysms. Founded in 2017, the company has developed an innovative treatment designed to stabilize the growth of aneurysms and prevent their rupture. This treatment delivers a compound containing a stabilizer agent directly to the aneurysm site, which helps inhibit further breakdown and strengthens the vessel wall. By providing a safer intervention option, Nectero Medical aims to enable patients to receive timely care, significantly delaying or preventing the need for major endovascular or surgical repair.

MMI S.r.l. is an Italian company that specializes in the manufacture and development of advanced micro instruments designed for surgical interventions. Founded in 2015 and based in Calci, Italy, MMI focuses on creating wristed micro instruments and their associated fabrication processes. The company also offers a proprietary robotic platform that enhances the capabilities of these instruments, facilitating complex reconstruction procedures following traumatic injuries and tumor removals in areas such as the breast, head, and bones. MMI aims to support surgeons globally by providing innovative tools that improve surgical outcomes while also reducing costs for patients and healthcare systems.

Amplitude Vascular Systems is a medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2020 and is based in Ann Arbor, Michigan.

Amplitude Vascular Systems is a medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2020 and is based in Ann Arbor, Michigan.

Amplitude Vascular Systems is a medical device company focused on safely and effectively treating severely calcified arterial disease. It was founded in 2020 and is based in Ann Arbor, Michigan.

REVA Medical, Inc. is a medical device company specializing in the development and commercialization of polymer-based bioresorbable products for vascular applications. The company focuses on innovative solutions for coronary artery disease and peripheral artery disease, offering its lead products: the Fantom Encore, a bioresorbable vascular scaffold for coronary artery treatment, and the MOTIV scaffold for below-the-knee applications. These products are designed to support the artery during the healing process and subsequently dissolve, restoring natural artery function. REVA Medical markets its Fantom Encore product in several European countries, including Germany, Austria, and Italy. Founded in 1998 and headquartered in San Diego, California, REVA Medical aims to improve patient health through the use of advanced biomaterials in implantable medical devices.

MMI S.r.l. is an Italian company that specializes in the manufacture and development of advanced micro instruments designed for surgical interventions. Founded in 2015 and based in Calci, Italy, MMI focuses on creating wristed micro instruments and their associated fabrication processes. The company also offers a proprietary robotic platform that enhances the capabilities of these instruments, facilitating complex reconstruction procedures following traumatic injuries and tumor removals in areas such as the breast, head, and bones. MMI aims to support surgeons globally by providing innovative tools that improve surgical outcomes while also reducing costs for patients and healthcare systems.

Ablative Solutions, Inc. is a clinical-stage medical device company focused on developing innovative treatments for hypertension. Incorporated in 2011 and headquartered in San Jose, California, with an additional office in Kalamazoo, Michigan, the company manufactures the Peregrine System, an endovascular catheter designed for the minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels. This technology provides a safe and effective alternative to traditional surgical renal denervation, aiming to reduce blood pressure in patients with hypertension that is not well controlled. By using alcohol as a neurolytic agent, Ablative Solutions' infusion catheter may offer significant advantages over energy-based systems, making it a promising option for managing hypertension and related conditions caused by an overactive sympathetic nervous system.

Foldax, Inc. is a company based in Salt Lake City, Utah, that specializes in the design and manufacture of synthetic heart valves for patients with aortic, mitral, or tricuspid valve disease. Founded in 2013, Foldax focuses on developing innovative heart valves made from a unique biopolymer technology that aims to provide non-thrombogenic solutions at significantly lower costs compared to traditional artificial or tissue valves. Their valves can be delivered through both transcatheter and surgical methods, offering a potential treatment option that may reduce or eliminate the need for long-term anticoagulant medications, thereby minimizing associated risks and side effects.

Aria CV, Inc. is a medical device company based in St. Paul, Minnesota, founded in 2010 by Drs. John Scandurra and Karl Vollmers. The company specializes in developing an implantable cardiovascular device aimed at treating pulmonary arterial hypertension (PAH). This innovative device is designed to reduce the workload on the right side of the heart, potentially enhancing both survival rates and the quality of life for patients suffering from this condition. Aria CV holds an exclusive license for certain patents from the University of Minnesota, reflecting its strong ties to academic research and innovation in the field of medical devices.

Corindus designs, manufactures, and commercializes remote robotic systems for interventional procedures. The company's products include CorPath, which enables physicians to perform catheterization procedures from a remote location away from the radiation zone. The company was formerly known as Navicath, Ltd. Corindus was founded in 2002 and is based in Waltham, Massachusetts.

Trice Medical, Inc. is a company that specializes in the development of innovative orthopedic diagnostic devices featuring integrated camera-enabled and needle-based technologies. Founded in 2011 and headquartered in Malvern, Pennsylvania, Trice Medical aims to enhance patient care by providing immediate and accurate diagnostic solutions that can be administered in a physician's office. Their products facilitate minimally invasive procedures that are designed to be painless, cosmetically undetectable, and of surgical grade quality. By optimizing the diagnostic process, Trice Medical seeks to eliminate inaccuracies associated with traditional indirect modalities, thereby reducing costs for the healthcare system while improving the overall patient experience.

Ablative Solutions, Inc. is a clinical-stage medical device company focused on developing innovative treatments for hypertension. Incorporated in 2011 and headquartered in San Jose, California, with an additional office in Kalamazoo, Michigan, the company manufactures the Peregrine System, an endovascular catheter designed for the minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels. This technology provides a safe and effective alternative to traditional surgical renal denervation, aiming to reduce blood pressure in patients with hypertension that is not well controlled. By using alcohol as a neurolytic agent, Ablative Solutions' infusion catheter may offer significant advantages over energy-based systems, making it a promising option for managing hypertension and related conditions caused by an overactive sympathetic nervous system.

V-Wave Ltd. is a private company that develops percutaneous implantable therapeutic devices for patients suffering from chronic heart failure. Founded in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave has created a proprietary interatrial shunt designed to alleviate symptoms associated with both preserved and reduced ejection fraction heart failure. This biocompatible implant regulates left atrial pressure, addressing a key factor in the deterioration of heart failure. The device aims to enhance patients' quality of life by reducing hospitalizations and improving exercise capacity. V-Wave's team consists of experienced engineers and medical scientists dedicated to advancing treatment options for individuals who continue to experience debilitating symptoms despite optimal medical care.

Corindus designs, manufactures, and commercializes remote robotic systems for interventional procedures. The company's products include CorPath, which enables physicians to perform catheterization procedures from a remote location away from the radiation zone. The company was formerly known as Navicath, Ltd. Corindus was founded in 2002 and is based in Waltham, Massachusetts.

CathWorks Ltd. is a medical technology company that specializes in enhancing percutaneous coronary intervention (PCI) therapy decisions through its advanced computational science platform. Founded in 2013 and headquartered in Kfar-Saba, Israel, with an additional office in the United States, the company has developed the CathWorks FFRangio, a non-invasive device that provides objective, multi-vessel physiologic measurements. This tool transforms coronary angiography from a subjective visual assessment into an objective decision-making framework based on fractional flow reserve (FFR) metrics. By utilizing sophisticated algorithms to process visual information, CathWorks aims to improve the efficiency of cath lab operations and support healthcare providers in making data-driven clinical decisions.

Trice Medical, Inc. is a company that specializes in the development of innovative orthopedic diagnostic devices featuring integrated camera-enabled and needle-based technologies. Founded in 2011 and headquartered in Malvern, Pennsylvania, Trice Medical aims to enhance patient care by providing immediate and accurate diagnostic solutions that can be administered in a physician's office. Their products facilitate minimally invasive procedures that are designed to be painless, cosmetically undetectable, and of surgical grade quality. By optimizing the diagnostic process, Trice Medical seeks to eliminate inaccuracies associated with traditional indirect modalities, thereby reducing costs for the healthcare system while improving the overall patient experience.

Corindus designs, manufactures, and commercializes remote robotic systems for interventional procedures. The company's products include CorPath, which enables physicians to perform catheterization procedures from a remote location away from the radiation zone. The company was formerly known as Navicath, Ltd. Corindus was founded in 2002 and is based in Waltham, Massachusetts.

TransMedics Group Inc is a commercial-stage medical technology company focused on transforming organ transplant therapy for patients with end-stage organ failure. The company has developed the Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system designed to overcome the limitations of traditional cold storage methods for organ preservation. By replicating near-physiologic conditions for donor organs outside the human body, the OCS enhances the viability and functionality of organs prior to transplantation, thereby improving clinical outcomes. TransMedics aims to increase heart and lung transplant volumes while reducing learning curves for healthcare providers, ultimately addressing critical needs in organ transplantation.

TransMedics Group Inc is a commercial-stage medical technology company focused on transforming organ transplant therapy for patients with end-stage organ failure. The company has developed the Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system designed to overcome the limitations of traditional cold storage methods for organ preservation. By replicating near-physiologic conditions for donor organs outside the human body, the OCS enhances the viability and functionality of organs prior to transplantation, thereby improving clinical outcomes. TransMedics aims to increase heart and lung transplant volumes while reducing learning curves for healthcare providers, ultimately addressing critical needs in organ transplantation.

V-Wave Ltd. is a private company that develops percutaneous implantable therapeutic devices for patients suffering from chronic heart failure. Founded in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave has created a proprietary interatrial shunt designed to alleviate symptoms associated with both preserved and reduced ejection fraction heart failure. This biocompatible implant regulates left atrial pressure, addressing a key factor in the deterioration of heart failure. The device aims to enhance patients' quality of life by reducing hospitalizations and improving exercise capacity. V-Wave's team consists of experienced engineers and medical scientists dedicated to advancing treatment options for individuals who continue to experience debilitating symptoms despite optimal medical care.

Kona Medical, Inc. is a medical technology company founded in 2009 and based in Issaquah, Washington. It specializes in the development of a non-invasive ultrasound-based therapy system aimed at treating hypertension, particularly in patients with drug-resistant hypertension. The company's flagship product, Surround Sound, utilizes ultrasound imaging to precisely guide the application of focused ultrasound energy for renal denervation, targeting the nerves connected to the kidneys to help regulate blood pressure. By offering a less invasive alternative to traditional treatments, Kona Medical seeks to address the health risks associated with high blood pressure while improving patient outcomes through advanced therapeutic techniques.

Aria CV, Inc. is a medical device company based in St. Paul, Minnesota, founded in 2010 by Drs. John Scandurra and Karl Vollmers. The company specializes in developing an implantable cardiovascular device aimed at treating pulmonary arterial hypertension (PAH). This innovative device is designed to reduce the workload on the right side of the heart, potentially enhancing both survival rates and the quality of life for patients suffering from this condition. Aria CV holds an exclusive license for certain patents from the University of Minnesota, reflecting its strong ties to academic research and innovation in the field of medical devices.

Trice Medical, Inc. is a company that specializes in the development of innovative orthopedic diagnostic devices featuring integrated camera-enabled and needle-based technologies. Founded in 2011 and headquartered in Malvern, Pennsylvania, Trice Medical aims to enhance patient care by providing immediate and accurate diagnostic solutions that can be administered in a physician's office. Their products facilitate minimally invasive procedures that are designed to be painless, cosmetically undetectable, and of surgical grade quality. By optimizing the diagnostic process, Trice Medical seeks to eliminate inaccuracies associated with traditional indirect modalities, thereby reducing costs for the healthcare system while improving the overall patient experience.

Conventus Orthopaedics provides a range of orthopedic and sports medicine services. The physicians specialize in orthopedic surgery, reconstructive surgery, spine surgery, joint replacement, sports medicine, physical therapy, and operative care of fractures, arthritis, strains, sprains, and sports-related injuries. Conventus was formed by a team of medical professionals with the sole purpose of creating less invasive ways to treat challenging periarticular fractures. By leveraging advanced nitinol technology, the Conventus team has developed a platform technology that provides robust fixation and creates reliable repairs. The company was incorporated in 2009 and is based in Maple Grove, Minnesota.

VytronUS, Inc. specializes in the manufacture and marketing of cardiac medical devices aimed at treating cardiac arrhythmias. Founded in 2006 and located in Sunnyvale, California, the company focuses on leveraging ultrasound energy to enhance the imaging and therapeutic capabilities of its devices. These innovative products allow for precise non-contact energy delivery and facilitate the production of high-resolution maps of cardiac anatomy. By providing physicians with tools that enable visualization, precision, flexibility, and automation, VytronUS aims to improve the treatment of complex arrhythmias.

Trice Medical, Inc. is a company that specializes in the development of innovative orthopedic diagnostic devices featuring integrated camera-enabled and needle-based technologies. Founded in 2011 and headquartered in Malvern, Pennsylvania, Trice Medical aims to enhance patient care by providing immediate and accurate diagnostic solutions that can be administered in a physician's office. Their products facilitate minimally invasive procedures that are designed to be painless, cosmetically undetectable, and of surgical grade quality. By optimizing the diagnostic process, Trice Medical seeks to eliminate inaccuracies associated with traditional indirect modalities, thereby reducing costs for the healthcare system while improving the overall patient experience.

Domain Surgical is a medical device company that is creating energy-based surgical products for precise soft tissue cutting and coagulation. It creates energy-based equipment used in specialty surgical procedures. Its patent-pending technology produces surface-only tissue effects with energy that does not pass through the patient designed with the surgical staff in mind, for simple user-interface and training. The company manufactures and markets the FMwand Ferromagnetic Surgical System, a hemostatic dissection device that uses pure thermal energy to cut and coagulate soft tissue, without passing an electrical current through the patient. The FMwand imparts as little as 1/10th the amount of thermal injury compared to traditional electrosurgery devices. The FMwand provides fine dissection with a layer-by-layer precision that is unmatched by existing surgical technology.

Ablative Solutions, Inc. is a clinical-stage medical device company focused on developing innovative treatments for hypertension. Incorporated in 2011 and headquartered in San Jose, California, with an additional office in Kalamazoo, Michigan, the company manufactures the Peregrine System, an endovascular catheter designed for the minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels. This technology provides a safe and effective alternative to traditional surgical renal denervation, aiming to reduce blood pressure in patients with hypertension that is not well controlled. By using alcohol as a neurolytic agent, Ablative Solutions' infusion catheter may offer significant advantages over energy-based systems, making it a promising option for managing hypertension and related conditions caused by an overactive sympathetic nervous system.

Trice Orthopedics, Inc. is based in King of Prussia, Pennsylvania, and specializes in camera-enabled needle technology designed for diagnostic and therapeutic procedures in orthopedics. The company aims to enhance orthopedic diagnostics and treatments by facilitating instant and accurate procedures in office settings. Trice's innovative technologies incorporate miniaturized opto-electronics into clinical solutions, providing immediate and definitive patient care. This approach addresses the limitations of traditional indirect modalities, reducing the risk of false readings while also lowering costs for the healthcare system through the use of existing reimbursement codes. The company's solutions are intended to benefit patients, physicians, and payers alike.

Trice Medical, Inc. is a company that specializes in the development of innovative orthopedic diagnostic devices featuring integrated camera-enabled and needle-based technologies. Founded in 2011 and headquartered in Malvern, Pennsylvania, Trice Medical aims to enhance patient care by providing immediate and accurate diagnostic solutions that can be administered in a physician's office. Their products facilitate minimally invasive procedures that are designed to be painless, cosmetically undetectable, and of surgical grade quality. By optimizing the diagnostic process, Trice Medical seeks to eliminate inaccuracies associated with traditional indirect modalities, thereby reducing costs for the healthcare system while improving the overall patient experience.

Angioslide, Ltd. is a medical device company established in 2005 and headquartered in Natanya, Israel, with additional subsidiaries in Karlsruhe, Germany, and Edina, Minnesota. The company specializes in developing innovative angioplasty products, notably the Angioslide eXtra balloon catheter, which serves both as a stand-alone balloon for angioplasty and as a device for debris removal. Its proprietary Embolic Capture Angioplasty™ technology allows physicians to capture and eliminate embolic particles, chronic thrombus, and atherosclerotic plaque debris during angioplasty procedures. Angioslide focuses on addressing the needs of various markets, including peripheral artery, lower limb artery, carotid, and coronary artery diseases.

Kona Medical, Inc. is a medical technology company founded in 2009 and based in Issaquah, Washington. It specializes in the development of a non-invasive ultrasound-based therapy system aimed at treating hypertension, particularly in patients with drug-resistant hypertension. The company's flagship product, Surround Sound, utilizes ultrasound imaging to precisely guide the application of focused ultrasound energy for renal denervation, targeting the nerves connected to the kidneys to help regulate blood pressure. By offering a less invasive alternative to traditional treatments, Kona Medical seeks to address the health risks associated with high blood pressure while improving patient outcomes through advanced therapeutic techniques.

Ablative Solutions, Inc. is a clinical-stage medical device company focused on developing innovative treatments for hypertension. Incorporated in 2011 and headquartered in San Jose, California, with an additional office in Kalamazoo, Michigan, the company manufactures the Peregrine System, an endovascular catheter designed for the minimally invasive delivery of diagnostic and therapeutic agents into the perivascular space surrounding peripheral blood vessels. This technology provides a safe and effective alternative to traditional surgical renal denervation, aiming to reduce blood pressure in patients with hypertension that is not well controlled. By using alcohol as a neurolytic agent, Ablative Solutions' infusion catheter may offer significant advantages over energy-based systems, making it a promising option for managing hypertension and related conditions caused by an overactive sympathetic nervous system.

Kona Medical, Inc. is a medical technology company founded in 2009 and based in Issaquah, Washington. It specializes in the development of a non-invasive ultrasound-based therapy system aimed at treating hypertension, particularly in patients with drug-resistant hypertension. The company's flagship product, Surround Sound, utilizes ultrasound imaging to precisely guide the application of focused ultrasound energy for renal denervation, targeting the nerves connected to the kidneys to help regulate blood pressure. By offering a less invasive alternative to traditional treatments, Kona Medical seeks to address the health risks associated with high blood pressure while improving patient outcomes through advanced therapeutic techniques.

CV Ingenuity, a Palo Alto, CA-based medical device company. CV Ingenuity Corp., a medical device company, develops devices for the treatment of vascular diseases to relieve vascular obstructions, inhibit restenosis, and allow natural vessel healing. It offers Drug Coated Balloon platform for the "Touch-and-Go" treatment of vascular disease. It was incorporated in 2008 and is based in Fremont, California. As of January 10, 2013, CV Ingenuity Corp. operates as a subsidiary of Covidien plc.

Ellipse Technologies is a privately-held medical device company based in California, specializing in the development of innovative implantable remote control technology for spinal and orthopedic applications. The company focuses on creating non-invasively adjustable implants designed to address a wide range of conditions, including spinal deformities and orthopedic trauma. Its flagship products include the MAGEC MAGnetic Expansion Control System, which employs a minimally-invasive method to correct spinal deformities through remote adjustment using an external magnetic field, and the PRECICE System, which utilizes adjustable intramedullary rods or bone plates to manage long-bone abnormalities resulting from fractures. Ellipse is dedicated to advancing treatment options in the fields of spinal and orthopedic medicine.

Reverse Medical is a commercial-stage medical device company dedicated to developing innovative solutions for revascularizing patients suffering from acute ischemic strokes. The company specializes in creating embolic protection systems aimed at treating neurovascular disorders, with a strong emphasis on endovascular management of acute stroke conditions. Through its advanced medical technologies, Reverse Medical seeks to improve patient outcomes and enhance the overall standard of care in the treatment of stroke.

Embrella Cardiovascular, Inc. is a company based in Malvern, Pennsylvania, specializing in the development of a system designed to improve embolic cerebral protection. This innovative system aims to assist interventionalists in minimizing the occurrence of embolic strokes during cardiovascular procedures. By focusing on enhancing patient safety, Embrella Cardiovascular addresses a critical need in the healthcare sector, particularly in the realm of cardiovascular interventions.

Revascular Therapeutics is a medical device company that develops solutions for the intravascular treatment of complex lesions and total occlusions. Revascular develops percutaneous medical devices to reopen occluded vessels.

SynergEyes, Inc. is a technology-driven company specializing in the manufacture and sale of contact lenses for eye care professionals. Founded in 2001 and based in Carlsbad, California, SynergEyes focuses on hybrid contact lenses that combine the clarity of rigid gas permeable lenses with the comfort of soft lenses. Their product offerings cater to various eye conditions, including astigmatism, presbyopia, myopia, hyperopia, and keratoconus. By utilizing advanced high-Dk materials and vision-optimized designs, SynergEyes aims to enhance vision and quality of life for its patients. The company's products are distributed in the United States and internationally, addressing a recognized need for innovative lens solutions in the eye care industry.

Corindus designs, manufactures, and commercializes remote robotic systems for interventional procedures. The company's products include CorPath, which enables physicians to perform catheterization procedures from a remote location away from the radiation zone. The company was formerly known as Navicath, Ltd. Corindus was founded in 2002 and is based in Waltham, Massachusetts.

AorTx, Inc. develops device solutions for percutaneous replacement of the aortic valve in the United States. Its devices cover the procedural solution for heart valve therapy from the implant to delivery and deployment of the valve. AorTx, Inc. was formerly known as CardiacMD, Inc. The company is based in Redwood City, California. As of November 15, 2007, AorTx, Inc. operates as a subsidiary of Hansen Medical, Inc.

Avantis Medical Systems, Inc. is a medical device company based in Sunnyvale, California, focused on developing catheter-based endoscopic devices aimed at detecting and treating cancers and other abnormalities in the gastrointestinal (GI) tract. The company leverages advanced technologies, including micro-chips and reinforced catheters, to create innovative solutions that enhance healthcare visualization and improve patient outcomes. With a team possessing extensive experience in the medical device industry, Avantis is dedicated to providing safe, cost-effective services that facilitate faster recovery for patients.

Pynk is a wealth management platform that leverages Artificial Intelligence to harness the collective intelligence of its global crowd, which spans over 185 countries. By gathering predictions and forecasts on financial assets from its members, Pynk employs machine learning to analyze and interpret market trends, supporting more informed investment decisions. Founded in 2018 by entrepreneurs Seth Ward, Rupert Barksfield, and Mark Little, Pynk aims to democratize investment insights through its innovative 'Crowd Wisdom' system. The company has successfully raised $2 million in pre-seed and seed funding and continues to seek additional investment to further develop its platform. Pynk is also backed by prominent financial institutions in the UK, positioning itself to enhance the investing experience for both novice and seasoned investors.

Broncus Medical is a medical technology company specializing in the development of minimally-invasive devices for treating lung diseases, including emphysema and lung cancer. Based in Mountain View, California, with an international presence in Nyon, Switzerland, Broncus is focused on addressing significant unmet medical needs in interventional pulmonology. The company is exploring its Exhale product line, which features a patented treatment method known as Airway Bypass, aimed at providing a minimally-invasive solution for patients suffering from homogeneous emphysema. Broncus is currently conducting the pivotal EASE Trial, enrolling patients worldwide to evaluate the efficacy of this treatment in severe cases of the disease. Additionally, Broncus offers a range of innovative products designed to enhance diagnostic and therapeutic outcomes in lung care, including the Archimedes System, LungPoint, and InterVapor System.

Avantis Medical Systems, Inc. is a medical device company based in Sunnyvale, California, focused on developing catheter-based endoscopic devices aimed at detecting and treating cancers and other abnormalities in the gastrointestinal (GI) tract. The company leverages advanced technologies, including micro-chips and reinforced catheters, to create innovative solutions that enhance healthcare visualization and improve patient outcomes. With a team possessing extensive experience in the medical device industry, Avantis is dedicated to providing safe, cost-effective services that facilitate faster recovery for patients.