Principia SGR

KLISBio is a company focused on advancing regenerative medicine by utilizing silk as a versatile and biocompatible scaffold material. The company develops innovative medical technologies aimed at improving tissue regeneration methods, specifically targeting clinical applications in orthopaedics and vascular health. Its silk-based biomaterials are designed to regenerate human tissues, including those in the vascular system, and are engineered to degrade and be safely absorbed by the body. This approach enables medical research entities to harness the benefits of nano-fibers for the treatment of various tissue-related diseases.

WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Enterome SA is a biopharmaceutical company based in Paris, France, with an additional office in Cambridge, Massachusetts. Founded in 2008, the company specializes in developing innovative disease management solutions that leverage the understanding of the gut microbiome. Enterome focuses on creating biomarkers, companion diagnostics, and therapeutics targeted at microbiome-related diseases, including inflammatory bowel diseases and metabolic disorders. The company’s OncoMimic technology addresses cancer by mimicking tumor-associated antigens, thereby inducing a strong immune response against solid tumors. Enterome's drug candidates are designed to modulate the immune system and are currently advancing through clinical trials, with several programs in Phase 2 targeting challenging cancers such as glioblastoma, adrenal malignancies, and colorectal cancer. The company has formed a strategic collaboration with Takeda Pharmaceutical Company to enhance its research and development efforts.

COMPASS Pathways plc is a mental health care company based in the United Kingdom and the United States, focusing on developing innovative therapies for treatment-resistant depression. The company is conducting Phase IIb clinical trials for its psilocybin formulation, COMP360, which aims to provide a new treatment option for patients who have not responded to conventional therapies. By researching psilocybin-assisted therapy, COMPASS Pathways seeks to assess its safety and efficacy, while combining the psychedelic compound with psychological support. The company was incorporated in 2020 and aims to address the significant unmet need for effective and accessible mental health treatments, striving to empower individuals facing mental health challenges.

ComfTech s.r.l. is a company based in Monza, Italy, that specializes in developing and marketing wearable monitoring systems for newborns. Founded in 2010, ComfTech designs sensorized garments that facilitate continuous, non-invasive monitoring of various physiological parameters. These smart garments are easy to dress and use, ensuring comfort for both the newborn and their caregivers. The products are developed in close collaboration with medical professionals, resulting in solutions that prioritize technological advancement while remaining user-friendly. ComfTech's innovative approach has garnered positive feedback from healthcare providers and families, highlighting the effectiveness and practicality of its monitoring systems in the neonatal care market.

CrestOptics is a company specializing in the development and manufacture of advanced systems for fluorescence microscopy. Based in Rome, Italy, the firm leverages its proximity to renowned research institutions to foster collaboration on innovative projects, including partnerships with organizations like CNR – FISBAT. CrestOptics focuses on creating high-performance microscopy instruments that utilize optical and electrooptical technology, enhancing sensitivity, image quality, and clarity for both scientific and industrial applications. The company also benefits from the expertise of its partner, Crisel Instruments, which has over 15 years of experience in live cell imaging systems. Through its commitment to research and development, CrestOptics aims to provide state-of-the-art solutions tailored to the needs of the research community and various industrial sectors.

Enterome SA is a biopharmaceutical company based in Paris, France, with an additional office in Cambridge, Massachusetts. Founded in 2008, the company specializes in developing innovative disease management solutions that leverage the understanding of the gut microbiome. Enterome focuses on creating biomarkers, companion diagnostics, and therapeutics targeted at microbiome-related diseases, including inflammatory bowel diseases and metabolic disorders. The company’s OncoMimic technology addresses cancer by mimicking tumor-associated antigens, thereby inducing a strong immune response against solid tumors. Enterome's drug candidates are designed to modulate the immune system and are currently advancing through clinical trials, with several programs in Phase 2 targeting challenging cancers such as glioblastoma, adrenal malignancies, and colorectal cancer. The company has formed a strategic collaboration with Takeda Pharmaceutical Company to enhance its research and development efforts.

Clinical Trial Center S.P.A. offers clinic research and trial services.

TRIFARMA S.p.A. is a manufacturer and distributor of active pharmaceutical ingredients (APIs), headquartered in Milan, Italy. Established in 1983, the company offers a diverse range of products that cater to various therapeutic areas, including anti-osteoporosis, progestogen, expectorant, anticonvulsant, glucocorticoid, antibacterial, antidepressant, anti-inflammatory, and many others. TRIFARMA emphasizes the development of APIs, particularly those related to antibiotics and drugs for the nervous system, which allows it to support the healthcare sector effectively. The company's operations facilitate a rapid transition from laboratory development to industrial scale production, ensuring timely delivery of essential pharmaceutical ingredients to its clients.

WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Enterome SA is a biopharmaceutical company based in Paris, France, with an additional office in Cambridge, Massachusetts. Founded in 2008, the company specializes in developing innovative disease management solutions that leverage the understanding of the gut microbiome. Enterome focuses on creating biomarkers, companion diagnostics, and therapeutics targeted at microbiome-related diseases, including inflammatory bowel diseases and metabolic disorders. The company’s OncoMimic technology addresses cancer by mimicking tumor-associated antigens, thereby inducing a strong immune response against solid tumors. Enterome's drug candidates are designed to modulate the immune system and are currently advancing through clinical trials, with several programs in Phase 2 targeting challenging cancers such as glioblastoma, adrenal malignancies, and colorectal cancer. The company has formed a strategic collaboration with Takeda Pharmaceutical Company to enhance its research and development efforts.

AnaBios is a contract research organization (CRO) focused on enhancing drug discovery through human-centric methodologies. The company offers a range of products and services that cover all phases of drug development, utilizing proprietary technology that leverages human donor organs and tissues. This approach allows AnaBios to investigate ex vivo human responses to drugs, providing insights into the molecular and functional aspects of human physiology. The research primarily targets significant unmet medical needs in areas such as cardiac disease, pain management, polycystic kidney disease, and neurodegeneration. By collaborating with pharmaceutical companies, contract research organizations, and academic institutions, AnaBios aims to generate predictive human data that improves the selection of effective and safe drugs, ultimately reducing costs and time associated with clinical trial failures while advancing therapeutic solutions to enhance patient health and quality of life.

Pedius is a communication platform designed to assist deaf individuals in making phone calls with ease. By utilizing voice recognition technology, the system transcribes spoken responses in real-time, allowing users to engage in conversations with hearing individuals through a smartphone app. Users can initiate calls by typing or speaking messages, receiving immediate transcriptions of the responses on the other end. This service is particularly valuable for making essential calls, such as scheduling appointments or contacting family and friends, especially when reaching individuals accessible only by phone. Pedius not only facilitates effective communication but also prioritizes user privacy throughout the process.

Ixaltis is a pharmaceutical company focused on developing therapeutics for genitourinary disorders that have unmet medical needs. Founded by a team of experts in urology and pharmaceuticals, the company aims to create innovative treatments by repurposing drugs that have already reached clinical stages for use in urogenital conditions. Ixaltis has established a proprietary position with Litoxetine, a drug leveraging its unique mechanism of action to address urogenital and other disorders. The company's goal is to enhance patient outcomes, particularly in improving urinary continence, through its novel pharmaceutical products.

RigeneranD is committed to develop biomedical devices supporting the culture of stem cells for pre-clinical and clinical applications.Founded in 2009 by Prof. Massimo Dominici and Prof. Pierfranco Conte, as a spin-off resulting from a joint venture between biomedical company RanD and researchers from the University of Modena and Reggio Emilia, Rigenerand owns proprietary technology to develop and produce biomedical tools to empower the ex-vivo phase of stem cells expansion combining the need of high cell yield with innovative biocompatible materials.

KLISBio is a company focused on advancing regenerative medicine by utilizing silk as a versatile and biocompatible scaffold material. The company develops innovative medical technologies aimed at improving tissue regeneration methods, specifically targeting clinical applications in orthopaedics and vascular health. Its silk-based biomaterials are designed to regenerate human tissues, including those in the vascular system, and are engineered to degrade and be safely absorbed by the body. This approach enables medical research entities to harness the benefits of nano-fibers for the treatment of various tissue-related diseases.

Comecer, or Costruzioni Meccaniche Certificate, is a prominent manufacturer specializing in protection technologies for nuclear medicine and isolation technology. The company designs and produces specialized screening systems and equipment tailored for large industrial groups and research organizations, including hospitals, universities, and pharmaceutical companies. Their focus includes the development of isolators for handling toxic and hazardous substances. Additionally, Comecer provides equipment for nuclear power plants, facilitating the processing, decommissioning, and disposal of radioactive materials. By creating innovative medical equipment for the management and processing of radiopharmaceuticals, Comecer supports advancements in healthcare and related sectors, ensuring robust and flexible solutions for its clients.

DoveConviene S.R.L. designs and develops a digital platform which helps people to shop by saving money through offers and leaflets presented georeferenced manner. The company was founded in 2010 and is based in Sestu, Italy. The startup trades under the brand DoveConviene in Italy and ShopFully in the U.S., as well as various other names in Spain, Brazil, Mexico and Indonesia (TechCrunch).

WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Tacatì, an Asti, Italy-based online grocery shopping platform. Created in 2012 by Giulia Valente and Stefano Cravero, Tacatì allows users to do grocery shopping online and receive local bio products at home, office or wherever they want. They can pay either online or at the time of receipt of items.

Affaredelgiorno provides online discount coupons on food and non-food products. Antonio Folino founded it in 2013, with its headquarters in Itá in Brazil.

Rysto is a pioneering social platform designed for the restaurant and hospitality labor market, facilitating the connection between businesses and potential employees. It enables companies in the catering and food service sectors to efficiently fill both temporary and permanent job vacancies through a geo-located, real-time system. This approach addresses challenges such as employee no-shows and fluctuating demand due to seasonality. In addition to job placements, Rysto's platform also focuses on identifying and training qualified professionals, enhancing the overall quality of service and product offerings within the industry. The company's vision is to establish itself as a leading provider of innovative solutions for the restaurant and hospitality sectors, benefiting businesses, customers, and employees alike.

Weekend-a-gogo is a company based in Naples, Italy, specializing in offering weekend packages designed for tourists. The business focuses on creating memorable travel experiences by curating a range of activities and accommodations that cater to diverse interests. Through its packages, Weekend-a-gogo aims to enhance the weekend getaway experience for visitors, allowing them to explore and enjoy the local culture and attractions.

D-Share is an international company focused on digital publishing and media. Combining technological skills, comprehensive expertise in publishing business and unparalleled experience, D-Share collaborates with clients to explore new, advanced business models based on next generation technologies. We provide worldwide publishers with end-to-end solutions, user experience development and services through our offices in Italy (D-Share Srl) and the United States of America (D-Share U.S.A., Corp.).

DoveConviene S.R.L. designs and develops a digital platform which helps people to shop by saving money through offers and leaflets presented georeferenced manner. The company was founded in 2010 and is based in Sestu, Italy. The startup trades under the brand DoveConviene in Italy and ShopFully in the U.S., as well as various other names in Spain, Brazil, Mexico and Indonesia (TechCrunch).

im3D Clinic Sud develops technologies for 3D screening in the field of cancer prevention.

WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Bangbite S.r.l. offers online soccer management games. It provides OFootball, website and mobile phone application game about management of a virtual football team. The company was founded in 2009 and is based in Sassari, Italy.

Jusp is a mobile payment platform that transforms smartphones into point-of-sale devices, allowing merchants to accept card payments with ease. The company provides a card reader that connects through a mini-jack to any smart device, enabling the reading of card chips. Through its application, Jusp manages the transaction process, simplifying payments for both customers and businesses. This innovation reduces the complexity of payment transactions, making it easier for users to complete purchases with just a few taps on their devices.

StreetLib is a publishing facilitator that serves as a gateway to the global book market, which is valued at $143 billion, with a significant portion occurring outside the United States. Catering to both independent authors and large publishers, StreetLib provides extensive distribution for ebooks, audiobooks, comics, magazines, and print-on-demand paperbacks through a wide network of retail, digital library, and subscription service outlets. The platform offers various services, including catalog and metadata management, digital production tools, analytics, online marketing, and royalties management, allowing publishers to maintain control over their digital supply chains. StreetLib operates on a model with no upfront fees, taking a 10% commission on each sale, thereby facilitating access to international markets for publishers of all sizes.

Itsworld Sicilia operates digital system that monitors photovoltaic facilities. The company is based in Milan, Italy.

Eco4Cloud specializes in modernizing data centers through its infrastructure management software, which enhances efficiency and service quality while achieving significant energy savings. The company utilizes virtualization platforms, such as VMware vSphere and Microsoft Hyper-V, to host applications on virtual machines (VMs) allocated to physical servers. By consolidating VMs onto fewer servers, Eco4Cloud allows for the powering down of excess servers or switching them to low power states, thereby reducing electrical energy consumption. The software also implements automation policies that optimize resource utilization, preventing over-provisioning and associated costs. Additionally, Eco4Cloud's solution mitigates the risk of overload situations, ensuring consistent service quality for users. Automated management further alleviates the administrative and monitoring burdens typically associated with data center operations, making it an attractive option for cloud providers and large enterprises aiming to optimize their IT infrastructure.

4w MarketPlace è il network pubblicitario leader del mercato digitale italiano. Con oltre 12.000 editori, 500 siti web e mobile tra i più prestigiosi, raggiunge una reach pari al 70%, e un volume di impression mensili di oltre 7 miliardi. offre agli investitori pubblicitari un range completo di formati native per desktop, tablet e smartphone – dagli annunci contestuali, ai video, ai formati display – utilizzando una suite proprietaria che integra le migliori tecnologie disponibili. dal 2009 gestisce in esclusiva spazi adv sui siti del consorzio premium publisher network (ppn), fondato da gruppo rcs e gruppo editoriale l’espresso.

CicerOOs is an online platform that focuses on promoting travel destinations and their attractions worldwide through engaging and humorous content. The company provides a searchable portal that offers travel and tourism information, analyzing various online resources to make this content accessible to consumers. By combining entertainment with informative travel insights, CicerOOs aims to enhance the travel planning experience and encourage exploration of diverse locations.

Vivocha is a cloud-based platform that facilitates live support for online customers, allowing businesses to engage with prospects and clients directly on their websites. The service offers a variety of multi-channel communication options, including VoIP for audio and video interactions, chat, audio callbacks, and collaboration tools such as assisted browsing and document sharing. By providing these features, Vivocha enables companies to enhance customer interactions, ultimately aiming to increase sales and improve overall customer satisfaction.

Moneyfarm is a financial services company that offers an online wealth management platform aimed at helping individuals manage and grow their wealth effectively and transparently. The platform provides personalized investment advice, focusing on exchange-traded funds (ETFs) and trading activities. Users can create tailored investment portfolios based on their financial goals and risk tolerance, while also having the ability to monitor their investments and receive recommendations for portfolio balancing. By combining financial advisory services with execution capabilities, Moneyfarm seeks to make wealth management accessible and efficient for its clients.

Eco4Cloud specializes in modernizing data centers through its infrastructure management software, which enhances efficiency and service quality while achieving significant energy savings. The company utilizes virtualization platforms, such as VMware vSphere and Microsoft Hyper-V, to host applications on virtual machines (VMs) allocated to physical servers. By consolidating VMs onto fewer servers, Eco4Cloud allows for the powering down of excess servers or switching them to low power states, thereby reducing electrical energy consumption. The software also implements automation policies that optimize resource utilization, preventing over-provisioning and associated costs. Additionally, Eco4Cloud's solution mitigates the risk of overload situations, ensuring consistent service quality for users. Automated management further alleviates the administrative and monitoring burdens typically associated with data center operations, making it an attractive option for cloud providers and large enterprises aiming to optimize their IT infrastructure.

6sicuro is an online insurance service provider that specializes in comparing prices for various insurance products, including car and motorcycle insurance. The company has developed a digital platform that allows users to easily assess and compare different insurance options, helping them select and purchase the most suitable coverage to meet their needs. In addition to insurance, 6sicuro also offers tools for comparing mortgage prices, further enhancing its range of financial services.

Docebo Inc. offers a cloud-based learning platform designed to facilitate training for external workforces, partners, and customers across North America, Europe, and the Asia-Pacific region. The platform centralizes learning materials into a single management system, enhancing the learning process and increasing productivity. Key features include Docebo Learn for organizing and distributing content, Docebo Discover, Coach & Share for personalized and social learning, and Docebo Extended Enterprise for managing multiple audience portals. Additional offerings include integrations with Salesforce, a mobile app publisher, AI-powered virtual coaching, and tools for creating mobile learning environments. Docebo serves diverse industries, including technology, media, manufacturing, and financial services, primarily generating revenue through a subscription model based on the number of learners and modules utilized. Founded in 2005 and headquartered in Toronto, Canada, Docebo aims to drive engagement and growth through scalable and personalized learning solutions.

Citynews is an italian based network of local newspaper sites. Actually active in 9 cities Citynews planning to open in the 30 principal italian cities. Actually 1,4 million visits each months.

X2TV is owned by Beeweeb and participated by Quantica Sgr – Venture Capital through the Principia II fund. Beeweeb is a privately-owned company that has designed and developed Mobile and web 2.0 solutions for over 10 years. X2TV board of directors is composed by Giampiero Recco (Chairman), Enrico Donati (Chief Executive Officer) and Stefano Peroncini (Quantica SGR). The board of statutory auditors is composed by Giovanni Pinna Parpaglia (President) Andrea Bonelli and Marco Gramegna. X2TV’s first partner to launch an “augmented” TV broadcast in Italy was RAI with Voyager, hosted by Roberto Giacobbo at dinner time. Incorporated in November 2010, X2TV Srl is dedicated to the digital entertainment service X2TV; it was born as a spinoff of Beeweeb S.p.A. with the goal of developing and managing the service given in partnership with TV broadcasters. The Headquarters is located in Roma, via Giacomo Peroni 400/402. X2TV department is located in Sardinia Technology Park.

Altilia is an intelligent automation software company focused on democratizing artificial intelligence for enterprises, particularly in automating document-intensive processes. The company offers a no-code, SaaS-based platform that allows users of varying technical backgrounds to convert knowledge into algorithms for document processing. This platform utilizes advanced machine learning techniques to enable businesses to efficiently handle both simple, structured documents like invoices and complex, unstructured documents such as financial statements. Altilia's solutions cater to various industries, including banking, insurance, utilities, and retail, addressing a range of applications such as fraud detection, customer profiling, and risk assessment. Recently recognized by Gartner, Altilia is transitioning towards a marketplace model that provides bundled, ready-to-use solutions, thereby streamlining the implementation process and reducing traditional project costs and timelines.

Kee Square S.r.l., a spin-off company of the Politecnico di Milano, develops innovative techniques in video and audio signal processing for biometric identification and tracking, detection of hazardous events, and security applications in general. Kee Square products are designed and customized to fulfill the Law Enforcement and Commercial Markets requirements.

Correlec engages in searching, extracting, updating, and classifying data originating from various sources and grouping it into logical categories. The company is headquartered in Legnano, Italy.

Dialectica is a biotechnological company that produces neuronal cellular models. The company was founded in 2004 and is based in Milan, Italy.