Missouri Technology Corporation

Aferna Bio is a biotechnology research company.

Agragene, Inc. is a sustainable agricultural technology company based in San Diego, California, founded in 2017. The company specializes in developing Precision Guided Sterile Insect Technology (pgSIT), a CRISPR-based approach that modifies the genomes of insects and plants to control invasive crop pests and improve crop properties. Agragene's innovative technology focuses on creating sterile male insects that can effectively reduce wild populations through mating with wild females. This method not only aims to eradicate mosquito-borne diseases but also enhances the quality and productivity of key crops such as wheat, oats, cotton, strawberries, sugarcane, and sorghum. By utilizing advanced genome engineering, Agragene is poised to offer sustainable pest management solutions that are free from pesticides and chemicals, addressing the needs of farmers and promoting environmentally friendly agricultural practices.

Edison Agrosciences, Inc. is an agricultural biotechnology company based in Durham, North Carolina, established in 2013. It specializes in developing innovative biotechnological solutions for the production of plant-based industrial materials, particularly focusing on alternative rubber crops. The company employs advanced computational breeding and agronomic techniques to enhance rubber concentration in underutilized plant parts, thereby improving per-acre yields. Edison Agrosciences aims to provide sustainable natural rubber sourced from alternative sunflower crops, catering to consumer, medical, and industrial markets. With a growing intellectual property portfolio and a commitment to forming strategic partnerships, the company seeks to mitigate risks associated with pilot-scale crop and product validation while driving advancements in sustainable biomaterials.

Maximum Fidelity Surgical Simulations designs and produces medical, surgical, ophthalmic, and veterinary instruments and apparatus. The company specializes in hyper‑realistic medical education by creating a human‑like mechanical cadaver system that incorporates real human tissue and a perfusion system using Simblood and a pulsatile pump to replicate circulatory and cardiac functions. This technology allows trainees to experience operating room and trauma care scenarios without using a human body, thereby enhancing skill acquisition while eliminating risk to patients. Additionally, the firm supplies equipment for testing biomedical devices and prepares medical personnel for military trauma situations.

Azome Therapeutics is an early-stage drug discovery company that focuses on developing selective antagonists of the NLRP3 inflammasome, an inflammatory system that plays a role in the development of a wide range of disorders.

Foresight is led by a passionate team of tech, lending, and banking veterans and backed by Techstars and Northwestern Mutual.

King of the Curve is an EdTech startup focused on enhancing student learning experiences through a gamified test preparation platform. The company aims to help students reduce stress and boost their confidence while studying for significant exams such as the MCAT, NCLEX, PA-CAT, and RDE. Its platform features adaptive question banks, various review modes, and multiplayer options, all supported by detailed analytics and study tools. By creating an engaging and effective study environment, King of the Curve empowers students to achieve their academic goals.

Backstitch Inc. is a Kansas City-based company founded in 2012 that specializes in a platform for personalized employee communications. The platform serves business communicators by enabling them to create tailored communications for their teams, providing features such as push notifications, internal content, and industry news. Additionally, Backstitch's platform helps users analyze trends and behaviors, identify departmental allies, and measure the return on investment of their communications and engagement efforts. The company also develops an application that integrates a curated media monitoring platform, further enhancing its offerings for HR and internal communications teams.

Likarda is a biotechnology company focused on cell therapies and enabling technologies that improve delivery and function. Its Core-Shell Spherification platform encapsulates therapeutic cells in hydrogel microcapsules using biocompatible materials such as hyaluronic acid, PEG and PVA, enabling customizable formulations tailored to each therapy. The platform supports two delivery approaches: injectable, slow-release formulations that localize cells for enhanced efficacy, and immunoprotective coatings that protect cells during injection or transplantation for longer-term treatment. In addition to cell therapies, the hydrogel coating method can formulate and deliver peptides, antibodies and exosomes while preserving their activity at the target site. Likarda aims to advance therapies for diabetes and osteoarthritis, including islet-like cell delivery for diabetes and encapsulated stem cells for joint degeneration, through preclinical work in animal models.

Bioio is a biotechnology company that specializes in developing pharmaceutical therapies for cancer. It uses a proprietary Mechanism of Action Technologies (MOAT) platform, which employs focused ultrasound to study how drugs interact with biological systems. This allows Bioio to enhance drug efficacy, understand therapy failures, and precisely target specific proteins, ultimately aiming to extend and improve the quality of human life.

Barbell Logic is a fitness company that offers personalized online coaching services. They specialize in strength training, providing custom workout programs tailored to individual clients' needs. Their services also include nutrition coaching to support clients' fitness goals. The company aims to improve its clients' quality of life through strength and wellness.

Amptify is a leading provider of hearing healthcare services, leveraging a technology platform that connects users through mobile devices, the internet, video, and phone. Founded by a distinguished team of aural rehabilitation researchers at the Washington University in St. Louis, Amptify offers a comprehensive, evidence-based program designed for individuals with hearing loss. Its proprietary digital toolkit enhances communication abilities and supports the social, psychological, and physical well-being of patients. This innovative approach empowers hearing healthcare specialists to deliver personalized rehabilitation, making Amptify a significant player in the global hearing healthcare market.

ECHELON Med Tech creates and markets dual-use medical solutions with the goal of significantly enhancing the health of soldiers, veterans, and civilians.

Aegis Digital Health delivers solutions in virtual care and remote patient monitoring to healthcare providers, helping clinicians monitor patients outside traditional settings and manage care more efficiently.

Jordan Valley Innovation Centre is a state-of-the-art center for conducting cutting-edge research and development. It is an inventive innovation hub approach that focuses on working in tandem with companies to develop and advance new technologies. JVIC assists and bolsters businesses in the semiconductor sector.

API Innovation Center is a non-profit organization dedicated to enabling the delivery of a market-competitive commercial supply of US-made Active Pharmaceutical Ingredients (APIs).

Navigate Oncology specializes in developing cloud-based software for oncology clinics. Their platform automates and digitizes radiation oncology workflows, from patient consultation to treatment delivery, enhancing efficiency, reducing errors, and streamlining prior-authorization processes. This ultimately helps clinics improve patient care while lowering healthcare costs.

Founded in 2021, Solis Agrosciences specializes in plant science services for agtech companies. It accelerates scientific discovery and commercialization by offering R&D crop development services.

Allumin8 is a pioneering medical device company specializing in orthopedic and spine hardware. It focuses on developing innovative, patient-specific solutions that bridge the gap between hardware and biologics. The company's flagship product is a 3D-printed, porous therapeutic hardware screw, designed to facilitate bone ingrowth and reduce screw loosening, potentially lowering revision surgery rates. This advanced technology aims to enhance healing and recovery for patients undergoing spine surgery.

NuPeak Therapeutics is a biopharmaceutical company focused on developing innovative therapies for airway diseases, including asthma, chronic obstructive pulmonary disease (COPD), and respiratory viral infections. The company specializes in small-molecule kinase inhibitors aimed at correcting the reprogramming of epithelial stem cells and innate immune cells, particularly in the context of post-viral inflammation and cancer. Through its research and development efforts, NuPeak strives to address significant unmet medical needs in respiratory health, leveraging its expertise in drug discovery to create effective treatment options for patients suffering from these conditions.

Journeys Metabolic is a digital therapeutic platform that extends metabolic care from the clinic into the home. Its interoperable program is designed to address obesity and insulin resistance-related conditions by enabling health systems and accountable care organizations to transition toward value-based or fee-for-outcomes models with reduced provider burden. Grounded in several years of behavior modification, the physician-developed program integrates AI-enabled precision pathways, education through computer vision-enabled food analysis, and a proprietary biomarker of fat oxidation (Biosense) to guide nutritional interventions. The platform is HITRUST and EHR interoperable, supporting shared savings optimization across metabolic diseases and nutrition-related disorders. The approach emphasizes sustained lifestyle changes delivered over multi-month periods and aims to improve overall health outcomes while simplifying care delivery for clinicians and care teams.

Bryght Labs are connected gaming startup approachable to tech-enthusiasts and innovators with 48 combined years of experience in consumer tech. It also makes STEM-focused games more approachable.

Healium is a technology company that develops mental fitness tools and immersive, bio-data-driven experiences to support self-management of anxiety, sleep issues, burnout, and overall well-being. The platform links real-time biometric data from wearables such as heart rate and brain activity via EEG headbands to personalized video or VR assets, producing reactive media escapes controlled by the user’s physiology. By integrating wearable devices and sensors, Healium delivers data-driven content that adapts to the user in real time, aiming to reduce anxiety, improve mood, and build resilience for individuals and organizations. Peer-reviewed studies have reported rapid mood benefits and anxiety reduction in as little as four minutes.

Edison Agrosciences, Inc. is an agricultural biotechnology company based in Durham, North Carolina, established in 2013. It specializes in developing innovative biotechnological solutions for the production of plant-based industrial materials, particularly focusing on alternative rubber crops. The company employs advanced computational breeding and agronomic techniques to enhance rubber concentration in underutilized plant parts, thereby improving per-acre yields. Edison Agrosciences aims to provide sustainable natural rubber sourced from alternative sunflower crops, catering to consumer, medical, and industrial markets. With a growing intellectual property portfolio and a commitment to forming strategic partnerships, the company seeks to mitigate risks associated with pilot-scale crop and product validation while driving advancements in sustainable biomaterials.

API Innovation Center is a non-profit organization dedicated to enabling the delivery of a market-competitive commercial supply of US-made Active Pharmaceutical Ingredients (APIs).

iSite Media, LLC is a St. Louis-based company specializing in advertising and marketing services through innovative digital display technology. Established in 2015 and formerly known as Sitting Duck Advertising, the company focuses on delivering impactful brand promotions via a digital display network situated in restrooms. This unique positioning enables iSite Media to effectively engage consumers in a private setting, enhancing message recall and relevance. By leveraging location flexibility, the company bridges the gap between content and consumer, ensuring that advertising reaches the appropriate audience in a compelling manner. Since its inception, iSite Media has prioritized high-level engagement, recognizing the importance of targeting the right viewers for successful media campaigns. In 2017, it rebranded to underscore its commitment to modern advertising solutions.

Lindenwood University is a school in Saint Charles. Whether you are a busy working adult, recent high school graduate, or international student looking to study in the US, Lindenwood University (LU) might have what you are searching for in your pursuit of higher education. LU is a private, four-year institution that is founded on Judeo-Christian standards. It has undergraduate and graduate degrees on campus in an array of programs, including Biology, Computer/Graphic Arts, Fire and Paramedic Science, and Retail Merchandising. For those who are seeking a degree while working a job and need coursework to fit in with their busy schedule, LU provides courses in the evenings and online for added convenience. Financial aid is available to those who meet the criteria. Applications for financial assistance and admissions to LU can be done online or in person during a site visit. Beyond academics, the university offers students enriching experiences through athletic programs, clubs and organizations, leadership opportunities, and Greek life. It even built a recreational facility (Evans Commons) where students can hang out, watch movies, socialize, and meet new friends. If you like the idea of going to a larger school with a historic campus, extensive liberal arts curriculum, and full student life, consider Lindenwood University.

Launch KC is to attract and retain high-growth tech startups to Downtown Kansas City, Missouri. Meet your new colleagues and have the space you need. They’ll match your firm to seasoned business leaders to give you resources. Expand your business affordably. Their Data Center gives you better computing power, hosting, and data storage. Access higher bandwidth and work where you want, when you want with the freedom of their downtown wireless district. Grow your business. Take advantage of their tailored development incentives for your IT company. Test your ideas with state of the art equipment. Meet mentors and professionals who will develop your business. Partner with KCMO to develop or test an innovative solution for the City.

Codefi Works develops an ecosystem to train workers and entrepreneurs to build and expand the digital economies of rural communities.

Digital Sandbox KC is a Kansas City, Missouri-based venture studio that supports early-stage information technology ventures by providing proof-of-concept resources, access to technology, business and market experts, and funding for market validation, prototyping and beta testing.

MOSourceLink offers business support for entrepreneurs and small organizations.

Arch Grants is a nonprofit organization established in 2011 and based in St. Louis, Missouri, dedicated to fostering economic development and community revitalization. It offers $50,000 equity-free grants and pro bono support services to entrepreneurs who establish their early-stage businesses in the St. Louis area. Through its highly competitive Global Startup Competition, Arch Grants aims to attract and retain innovative entrepreneurs, thereby inspiring future employers and civic leaders. The competition operates year-round, with grants awarded biannually in spring and fall. Arch Grants focuses on funding scalable business models across various industries, targeting innovative technologies, products, and services that have the potential for national or international impact.

The eFactory is a business resource center located in southwest Missouri, specifically designed to support entrepreneurs and startups. It offers a 12-week intensive accelerator program aimed at jumpstarting emerging companies. Participants benefit from financial support, dedicated office space, and personalized mentoring, as well as business consulting services. The eFactory also facilitates introductions to potential follow-on funding sources and provides access to a recreation center, enhancing the networking opportunities available to its members. Through these resources, the eFactory fosters a collaborative environment that aims to promote innovation and growth within the local entrepreneurial ecosystem.

Plastomics Inc. is a biotechnology company that specializes in chloroplast genetic engineering to enhance crop performance and nutritional quality. Founded in 2016 and based in Saint Louis, Missouri, the company utilizes a proprietary technology platform to insert beneficial traits into the chloroplasts of plant cells. This innovative approach allows seed companies to develop advanced biotech crops with a diverse array of traits while addressing current industry challenges. Plastomics' technology not only eliminates cross-pollination but also facilitates unique maternal inheritance, significantly reducing breeding timelines and associated costs. By focusing on gene stacking and rapid breeding, Plastomics aims to improve yield production and contribute to the advancement of agricultural biotechnology.

Impetus AG is engaged in the development of innovative insect control solutions that prioritize safety, effectiveness, and sustainability. The company specializes in creating bi-specific plant-based proteins designed to protect crops from harmful insects. Utilizing Bacillus thuringiensis technology, Impetus AG's products enhance crop yield by integrating antibodies within plant structures. This approach addresses the challenge of insect resistance that has emerged with existing commercial insect control products, offering farmers durable alternatives that support sustainable agriculture.

Compatio AI develops intelligent systems that connect customers with suitable products. Its platform offers features like smart bundling, product recommendation, cross-selling, and dynamic catalog management, helping businesses enhance conversion rates, customer satisfaction, and loyalty while reducing operational costs.

Scopio, LLC is an innovative image search engine and licensing platform based in New York, founded in 2015. It connects photographers and visual artists with potential customers, forming a vast online community of diverse talent from 190 countries. The platform allows users to license trending images and videos from social media, enabling companies, brands, non-governmental organizations, and event organizers to build libraries of visual user-generated content. Scopio utilizes artificial intelligence to streamline the process of searching for, licensing, and publishing images and videos, while also simplifying the copyright management of these assets. By facilitating the connection between artists and clients, Scopio aims to increase accessibility to quality visual content on a global scale.

CellARide specializes in automotive marketing technology and safety recall communications. It works with various stakeholders like manufacturers, media groups, and advocacy organizations to understand consumer behavior and provide effective engagement methods. The company offers an intuitive platform for consumer insights, compliant communications, and data capture using mobile messaging technologies.

PlanIT Impact is a cloud-based software-as-a-service platform designed to enhance the building design process by providing architects, designers, engineers, developers, and planners with essential insights into return on investment and total cost of ownership. Utilizing AI-driven technology, the platform delivers cost-benefit analysis that maximizes energy efficiency, stormwater management, and water savings. This accessibility to sustainable design tools empowers professionals in the construction and property management sectors to minimize the environmental impact of their projects while optimizing financial performance. By integrating seamlessly with existing workflows, PlanIT Impact supports users in achieving their sustainability objectives without the fear of incurring unnecessary expenses during the early stages of design.

Mingo automates data collection from machines and devices on factory floors, providing real-time insights into productivity. Its platform enhances machine availability, productivity, and quality, helping clients boost operational efficiency and profitability.

CoverCress Inc. specializes in developing and commercializing field pennycress as a sustainable oilseed crop for industrial oils and livestock feed. Founded in 2013, the company is headquartered in Saint Louis, Missouri.

Digital Sandbox KC is a Kansas City, Missouri-based venture studio that supports early-stage information technology ventures by providing proof-of-concept resources, access to technology, business and market experts, and funding for market validation, prototyping and beta testing.

PatientsVoices, LLC is a healthcare technology company based in Parkville, Missouri, founded in 2013. The company operates a platform that utilizes data analytics to transform patient feedback—derived from surveys, social media, and complaints—into actionable insights for hospitals. By employing experts in computing and linguistics, PatientsVoices has developed a system that automatically categorizes feedback into improvement priorities from the patient's perspective. This platform not only helps hospital administrators understand how to enhance patient satisfaction but also aims to increase Medicare reimbursements by summarizing patient insights into a user-friendly format. Currently, the platform is being tested in various hospitals, demonstrating its potential to significantly improve patient care experiences.

Canopy Biosciences, founded in 2016 and headquartered in St. Louis, Missouri, is a biotechnology company specializing in research tools for genetic engineering, molecular biology, and personalized medicine. The company offers a comprehensive range of products and services designed to facilitate gene editing, gene expression analysis, and bioprocessing. One of its key technologies, TUNR, targets translation elongation by inserting polyA tracks into specific coding regions of the genome, effectively reducing mRNA levels and suppressing protein expression. This innovative approach supports biomedical researchers at universities, research institutions, and within the biotechnology and pharmaceutical sectors, accelerating scientific discovery and enhancing the field of genetic engineering. Canopy Biosciences operates as a subsidiary of Bruker Corporation.

Geneoscopy develops non-invasive diagnostics using stool-derived eukaryotic RNA to prevent, detect, and guide treatment for gastrointestinal diseases. Its platform technology enables early-stage detection of colorectal cancer neoplasms and improves screening compliance.

Lean Media, Inc. is a digital advertising company specializing in cookieless audience targeting services tailored for agribusiness and rural community advertisers. Founded in 2014 and based in Chesterfield, Missouri, the company employs advanced geo-targeting technology to connect with consumers at an individual level by analyzing IP addresses in conjunction with consumer databases. Lean Media's platform enables advertisers to customize campaigns based on specific workplaces, demographics, psychographics, and behavioral insights, allowing for more effective engagement and reduced advertising waste. The company focuses on delivering confidence to advertisers by enhancing their ability to reach target consumers through programmatic online display advertising.

Aptimmune is a biotechnology company headquartered in St. Louis, Missouri, established in 2010. It specializes in the development of mucosal vaccines aimed at preventing viral diseases in swine, specifically targeting the Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and influenza A virus. By employing innovative technologies, including a proprietary pig alveolar macrophage cell line known as ZMAC, Aptimmune creates effective nasal delivery vaccines that provide lasting immune responses and enhance disease protection for animal breeders.

Keybot, Inc. is a company that designs and manufactures rental access robots, automating entry for rental properties through an innovative integration of hardware and software. Founded in 2018 and headquartered in St. Peters, Missouri, with additional locations in Kansas City and London, the company provides solutions for rental owners and property managers. Keybot's product facilitates self-showings and allows renters and maintenance personnel to access properties securely. The system employs digital keys that enable property managers to share access with verified third parties, manage locks remotely, and maintain access logs, thereby enhancing security and efficiency in property management. Keybot also operates a production office in Taipei City, Taiwan.

Tallyfy, Inc. is a company that develops online business process improvement and workflow management software, founded in 2014 and headquartered in St. Louis, Missouri, with an additional office in San Francisco, California. Its cloud-based platform focuses on automating and optimizing recurring workflows, allowing organizations, from Fortune 500 companies to small startups, to track processes in real-time, thereby reducing manual updates and enhancing efficiency. Tallyfy's software specializes in areas such as client onboarding, customer success, and compliance, enabling businesses to minimize human errors and streamline operations. Users can create templates, automate processes with conditional rules, and continuously improve workflows through feedback and metrics, fostering a culture of operational excellence.

Vector Legal Method is a software company based in Kansas City, Missouri, specializing in litigation management solutions. The company offers a cloud-based Software-as-a-Service platform designed specifically for corporate legal departments and law firms. This platform provides centralized control over litigation cases, enhancing visibility into outside counsel activities and offering instant access to case information. By streamlining document storage, retrieval, deadlines, and tasks, the platform enables collaborative management of cases among all stakeholders. This results in increased efficiency, reduced billable costs, and allows legal departments to focus on strategic projects.

PopBookings is a cloud-based staffing solution company that specializes in automating the hiring process for temporary and promotional staffing agencies. Founded in 2014 and headquartered in Lenexa, Kansas, PopBookings offers a comprehensive platform designed to simplify the booking and communication with promotional staff. Its features include database management, a custom-branded talent portal, drag-and-drop scheduling, geo check-ins, and an event dashboard with status alerts. By connecting agencies and brands with event workers, PopBookings facilitates the organization of events, helping to celebrate brands through effective staffing solutions.

Greetabl is an online gift platform that specializes in creating unique and personalized gifts for various occasions. The company allows users to transform their photos into greeting cards that double as gift boxes, enhancing the gifting experience. Customers can select from a variety of items, including gift cards, chocolates, and other thoughtful gifts, all at affordable prices starting at $20. Greetabl's focus on personalization and ease of use makes it simple for individuals to send meaningful presents to their loved ones.

CellARide specializes in automotive marketing technology and safety recall communications. It works with various stakeholders like manufacturers, media groups, and advocacy organizations to understand consumer behavior and provide effective engagement methods. The company offers an intuitive platform for consumer insights, compliant communications, and data capture using mobile messaging technologies.

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

Sickweather Inc. is a company that specializes in sickness forecasting and mapping through its innovative mobile application. Founded in 2011 and based in Windsor Mill, Maryland, Sickweather utilizes a unique social listening technology to monitor social networks for indicators of illness, allowing users to receive alerts about sickness trends in real-time. This predictive platform operates in over 120 countries and provides detailed illness forecasts, modeled into 15-week predictions along with a threat level index known as the SickScore. By crowdsourcing data about illnesses and analyzing population, sales, and clinical information, Sickweather empowers users to assess the likelihood of sickness in their area, akin to checking the weather forecast.

CoverCress Inc. specializes in developing and commercializing field pennycress as a sustainable oilseed crop for industrial oils and livestock feed. Founded in 2013, the company is headquartered in Saint Louis, Missouri.

Tallyfy, Inc. is a company that develops online business process improvement and workflow management software, founded in 2014 and headquartered in St. Louis, Missouri, with an additional office in San Francisco, California. Its cloud-based platform focuses on automating and optimizing recurring workflows, allowing organizations, from Fortune 500 companies to small startups, to track processes in real-time, thereby reducing manual updates and enhancing efficiency. Tallyfy's software specializes in areas such as client onboarding, customer success, and compliance, enabling businesses to minimize human errors and streamline operations. Users can create templates, automate processes with conditional rules, and continuously improve workflows through feedback and metrics, fostering a culture of operational excellence.

Strayos Inc., founded in 2016 and based in St. Louis, Missouri, specializes in developing aerial data analytics software for various industries including mining, drilling, blasting, quarrying, and oil and gas exploration. The company's platform utilizes image processing and artificial intelligence to provide highly accurate survey data analytics, transforming job site insights through 3D visual AI. Key offerings include smart drill data analysis using measurement-while-drilling techniques, 3D Blast Profile for optimizing blast patterns, and Muckpile and Rock Size Analysis through advanced machine learning. These solutions aim to reduce costs, improve productivity, and enhance safety by delivering actionable insights that maximize operational excellence.

BenchmarkONE is a St. Louis, Missouri-based company that specializes in developing sales and marketing automation software for small and mid-sized businesses. Founded in 2010 and previously known as Hatchbuck, Inc., BenchmarkONE provides an all-in-one customer relationship management (CRM) platform that includes features for sales automation, real-time activity monitoring, and email marketing. Its user-friendly interface allows businesses to create and manage campaigns, track leads, and analyze performance metrics effectively. The software is designed to streamline the sales process, enhance customer engagement, and facilitate the growth of relationships into sales. As of June 2020, BenchmarkONE operates as a subsidiary of Benchmark Internet Group, LLC.

TopOPPS, Inc. is a company that specializes in predictive analytics solutions for sales forecasting and pipeline management, primarily targeting business-to-business firms. Established in 2013 and headquartered in St. Louis, Missouri, TopOPPS offers tools that enhance visibility into sales processes, improve forecast accuracy, and facilitate alignment among sales teams. Its flagship product analyzes sales activities to identify coaching opportunities and optimize pipeline management, ultimately enabling organizations to achieve faster sales cycles and increased win rates. Additionally, the TopOPPS Rep Assistant integrates seamlessly with Gmail to capture data and provide real-time updates to Salesforce, further streamlining the sales process. Through its innovative approach, TopOPPS transforms sales pipeline confusion into actionable insights for sales executives and representatives alike.

Olio City, Inc. is a company based in Saint Louis, Missouri, that specializes in developing an online travel guide application aimed at enhancing city exploration. Founded in 2014, the app offers personalized city discovery by integrating curated content with an algorithm that adapts to individual user preferences. It features a comprehensive database of local experiences, including restaurants, attractions, and nightlife events, all curated by local experts and cultural enthusiasts. The application tailors recommendations based on users’ tastes, ensuring that whether one is interested in jazz music or Japanese cuisine, the suggestions align with their interests. Olio City enables users to seamlessly explore cities, uncovering nearby hotspots and enriching their travel experiences.

Better Weekdays, Inc. operates an online career services platform and mobile application known as The Whether. Founded in 2011 and based in Saint Louis, Missouri, the company provides a comprehensive suite of applications aimed at preparing students for employment. Its flagship product, Mentor Spaces, is a virtual mentorship platform that assists companies in identifying, hiring, and retaining underrepresented talent. In addition to this, Better Weekdays offers self-assessment, job matching, and career development services to both students and professionals. By leveraging personalized content marketing, the company helps university recruiters reduce their cost per hire while enabling employers to attract and retain top talent.

Recursive Labs offers a patented Visual Customer Engagement Platform that enables secure real-time co-browsing between users and customer service representatives. Its solutions include Realtime for Web and document sharing, Replay Social for viral marketing, Replay Support for time-shifted messaging, and Replay Enterprise for internal communications. Available as Software-as-a-service, the platform aims to enhance sales and support efforts across digital channels.

Appbase is a company based in Belo Horizonte, Brazil, that offers a hosted developer API designed for consuming JSON data streams using ElasticSearch. The platform enables developers to create reactive applications by facilitating the streaming of document updates, search results, and filters. In addition to its API services, Appbase provides database consulting for application development, assisting clients in optimizing their database architectures and enhancing their application performance.

Greetabl is an online gift platform that specializes in creating unique and personalized gifts for various occasions. The company allows users to transform their photos into greeting cards that double as gift boxes, enhancing the gifting experience. Customers can select from a variety of items, including gift cards, chocolates, and other thoughtful gifts, all at affordable prices starting at $20. Greetabl's focus on personalization and ease of use makes it simple for individuals to send meaningful presents to their loved ones.

SanusEO, LLC is a St. Louis-based company that specializes in developing a mobile patient engagement platform (PEP) designed to enhance communication and care between patients and healthcare providers. Founded in 2012, the platform employs data analytics to deliver daily alerts and real-time participant data to care teams, facilitating timely interventions for chronic disease management. SanusEO offers targeted programs such as transition care for patients recently discharged from hospitals and bootcamps for newly diagnosed or at-risk individuals. The platform promotes behavior modification in key health areas, including medication adherence, vital monitoring, diet, and physical activity, with capabilities for multi-language support. By streamlining engagement and intervention processes, SanusEO aims to improve patient outcomes while reducing healthcare costs.

BODITRAK SPORTS is a sports technology company based in Morning View, Kentucky, specializing in the interaction between athletes and the ground. The company focuses on developing innovative solutions that help instructors and athletes enhance performance while minimizing the risk of injury. By manufacturing golf goods and utilizing advanced technology, BODITRAK SPORTS aims to improve the overall athletic experience and provide valuable insights into an athlete's performance dynamics.

Janus Choice, LLC is a healthcare technology company focused on enhancing the hospital discharge process and facilitating informed transitions to post-discharge care. Founded in 2014 and headquartered in Rockford, Illinois, the company offers an innovative search engine that utilizes a patentable algorithm to match patients' clinical and social needs with appropriate skilled nursing facilities. This platform empowers patients and their families to make informed decisions about their care options while still in the hospital, thereby improving the overall patient experience and reducing hospital length of stay. By streamlining the discharge process, Janus Choice benefits not only patients and their families but also hospitals and skilled nursing facilities, contributing to a more efficient continuum of care. The company was established by individuals who recognized the challenges of navigating post-discharge care for their loved ones, leading to a solution that addresses the needs of all stakeholders involved in the healthcare transition process.

EternoGen is a medical biotechnology company founded in 2009 and headquartered in Columbia, Missouri. The company specializes in the design and manufacture of collagen scaffolds for therapeutic applications in soft tissue. EternoGen focuses on research and development, leveraging its expertise in clinical market evaluation, material science, and biological engineering to advance its clinical development model. Its innovative liquid collagen tissue products offer an alternative to traditional aesthetic treatments, enabling easy injection that creates an immediate natural collagen scaffold upon contact with skin. This process not only lifts wrinkled skin but also inhibits degradation, allowing dermal cells to gradually infill the scaffold over time, thereby restoring youthful fullness, texture, and elasticity to the skin.

StoryUP, Inc. specializes in developing virtual reality and augmented reality solutions aimed at reducing anxiety and providing digital therapeutics. Founded in 2015 and based in Columbia, Missouri, the company creates technology-enabled virtual reality videos tailored for brands, wellness organizations, and non-profits. One of its key offerings is Healium, an innovative platform that integrates brain-sensing wearables, allowing users to visualize and control virtual environments based on their emotions and physiological responses. StoryUP's unique, patent-pending methodology empowers users to self-prescribe immersive experiences that promote stress relief. The company serves a diverse clientele, including storytellers, psychologists, filmmakers, and technologists, contributing to the growing field of mental health and wellness through advanced immersive technology.

Sparo Labs is a St. Louis-based startup founded in 2012 that focuses on advancing respiratory care through innovative technology. The company's flagship product, Wing, is a pocket-sized device connected to a smartphone, designed to measure lung function with medical-grade accuracy. This device empowers patients to understand, track, and manage their asthma effectively, thereby reducing the fear and uncertainty associated with the condition. By allowing users to monitor their lung function, manage medications, and identify triggers and symptoms, Sparo Labs aims to transform the asthma management landscape and enhance the quality of life for individuals living with respiratory conditions.

LocalRaces.com LLC is a technology company based in Joplin, Missouri, that specializes in online race registration and event management services. Established in 2014, the company provides a comprehensive platform designed to enhance the experience of participants in endurance events such as running, cycling, and triathlons. LocalRaces.com facilitates race management for directors by offering an all-in-one web-based software suite that includes tools for registration, volunteer coordination, sponsorship, and vendor management. The platform processes registrations both online and onsite and acts as a payment facilitator, charging a fee to registrants while delivering valuable event management solutions to race directors. Additionally, LocalRaces.com boasts the largest network of local running and cycling communities in the U.S., hosting thousands of event and club profiles. Athletes benefit from web-based tools and mobile applications to manage their racing itineraries, results, and training goals. The company also generates revenue through featured event listings, display advertisements, and partnerships within the running shoe and apparel market.

CellARide specializes in automotive marketing technology and safety recall communications. It works with various stakeholders like manufacturers, media groups, and advocacy organizations to understand consumer behavior and provide effective engagement methods. The company offers an intuitive platform for consumer insights, compliant communications, and data capture using mobile messaging technologies.

Confluence gathers, filters, combines and presents the pharmaceutical intelligence you need. It turns manual into automatic, risk into reliability and wait into wow. With Confluence you start where it counts: crucial planning and decision-making. Skip the assembly, start with Confluence.

MedAware Solutions, Inc. is a healthcare technology company based in St. Louis, Missouri, founded in 2014. It specializes in providing a comprehensive platform that facilitates communication and coordination among healthcare teams, including providers, payers, patients, and their families. The company's flagship product, mViva, serves as an all-in-one care coordination tool that allows multi-disciplinary teams to engage with patients throughout the continuum of care. This secure, HIPAA-compliant platform enables users to capture and share data efficiently, fostering collaboration and enhancing patient outcomes. By empowering individuals to participate in real-time conversations and access connected care, MedAware Solutions aims to optimize clinical resources and reduce healthcare costs.

FocalCast LLC, founded in 2013 and located in St. Louis, Missouri, is a technology company that specializes in developing an interactive web-based platform for market research. The platform allows users to simultaneously share and annotate documents and whiteboards in real time from any device, enhancing collaboration for global brands and marketing agencies. FocalCast's offerings include tools for stimuli and content presentation, live annotations, project management, and polling and data services. Users can easily connect with research participants without needing to download additional software, facilitating seamless presentations directly from smartphones or tablets to display devices like projectors or smart TVs.

FinLocker, LLC is a financial technology company based in St. Louis, Missouri, founded in 2014. It specializes in developing a consumer-enabled financial data platform that enhances the loan process for mortgages and various financial products. FinLocker provides a personal financial assistant tool that captures essential borrower data with consumer consent, utilizing intelligent analytics to offer tailored loan product recommendations based on individual financial profiles. Its solutions aim to streamline lending processes by improving data collection, verification, and analytics, thereby reducing costs, time, and risks for lenders. Additionally, FinLocker enhances the borrower experience by enabling consumers to manage their finances more effectively, apply for loans with reduced documentation hassles, and control data sharing.

Founded in 2015, Accuronix Therapeutics is a biotechnology company dedicated to developing innovative oncology therapies. Its focus lies in creating targeted treatments for pancreatic cancer, aiming to enhance therapeutic efficacy while minimizing toxicity.

Edison Agrosciences, Inc. is an agricultural biotechnology company based in Durham, North Carolina, established in 2013. It specializes in developing innovative biotechnological solutions for the production of plant-based industrial materials, particularly focusing on alternative rubber crops. The company employs advanced computational breeding and agronomic techniques to enhance rubber concentration in underutilized plant parts, thereby improving per-acre yields. Edison Agrosciences aims to provide sustainable natural rubber sourced from alternative sunflower crops, catering to consumer, medical, and industrial markets. With a growing intellectual property portfolio and a commitment to forming strategic partnerships, the company seeks to mitigate risks associated with pilot-scale crop and product validation while driving advancements in sustainable biomaterials.

Nanopore Diagnostics, LLC is a St. Louis-based company founded in 2011 that specializes in developing rapid and portable diagnostic products for bacterial infections. Its flagship product, The iNDxer, is a nanopore sensor designed to count dilute amounts of nucleic acid biomarkers directly in minimally processed samples. This technology allows for the detection of RNA markers specific to pathogenic bacteria, enabling physicians to accurately identify the presence of harmful microbes. By providing timely and precise diagnostic information, Nanopore Diagnostics aims to assist healthcare providers in making informed antibiotic decisions, ultimately reducing healthcare costs and combating antibiotic resistance. The company's focus on delivering microbiology lab-quality testing at the patient's side represents a significant advancement in the field of diagnostics.

PayIt specializes in modernizing government payment systems by offering a cloud-based platform that enables digital transactions for various services such as taxes, utilities, courts, DMV, and outdoors. The company serves over 100 million residents across North America, improving operational efficiency and enhancing citizen satisfaction.

Founded in 2013, Bonfyre operates an employee engagement platform that facilitates communication, recognition, feedback, events, and more. Its mobile-first, real-time tools help enterprises build camaraderie, align culture, and drive HR business intelligence.

Nitrogenics is a plant biotechnology company providing research analysis on nitrogen fixation in crop plants. Nitrogenics' services include data related to plant enzymes that are inserted in the genome of tobacco, enabling researchers to get to research on plants that absorbs nitrogen directly from the atmosphere, rather than from fertilized soil.

MedSocket is a company that specializes in clinical decision support systems aimed at enhancing the efficiency and quality of patient care. It offers two patented technologies: the 1-Click Decision Support (1-CDS) system and a medical search engine called 1-Search. Designed by clinicians for clinicians, these tools provide rapid access to evidence-based information at the point of care, addressing the urgent information needs of healthcare providers. Both technologies have been successfully piloted at the University of Missouri Health System, demonstrating their potential to improve healthcare decisions, reduce errors, and ultimately enhance patient outcomes. MedSocket was founded by Dr. Karl Kochendorfer, who recognized the challenges healthcare providers faced in accessing timely information, and was later joined by Matt Botkin and Jayne Williams to bring together expertise in business and information science. The company aims to alleviate the burden on clinicians by streamlining information retrieval and decision-making processes in healthcare settings.

Antegrin Therapeutics, LLC, is a drug discovery and development company focused on the development of novel therapies for fibrotic diseases. Our lead program aims to develop a treatment for idiopathic pulmonary fibrosis, a progressive, life-threatening condition that currently has no FDA-approved medication.

MedSocket is a company that specializes in clinical decision support systems aimed at enhancing the efficiency and quality of patient care. It offers two patented technologies: the 1-Click Decision Support (1-CDS) system and a medical search engine called 1-Search. Designed by clinicians for clinicians, these tools provide rapid access to evidence-based information at the point of care, addressing the urgent information needs of healthcare providers. Both technologies have been successfully piloted at the University of Missouri Health System, demonstrating their potential to improve healthcare decisions, reduce errors, and ultimately enhance patient outcomes. MedSocket was founded by Dr. Karl Kochendorfer, who recognized the challenges healthcare providers faced in accessing timely information, and was later joined by Matt Botkin and Jayne Williams to bring together expertise in business and information science. The company aims to alleviate the burden on clinicians by streamlining information retrieval and decision-making processes in healthcare settings.

Orange EV manufactures heavy-duty industrial electric vehicles. Established in 2012, the company designs, manufactures, delivers, and services Class 8 trucks, offering charging solutions, demo drives, warranties, financial incentives, and financing options.

Euclises Pharmaceuticals, Inc. is a biopharmaceutical company focused on researching, developing, and commercializing innovative medicines for inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company aims to create novel pain and cancer treatments that demonstrate superior safety profiles compared to existing medications. Euclises Pharmaceuticals leverages groundbreaking inventions from Dr. John Talley, a renowned medicinal chemist known for his development of several approved drugs, including Celebrex. The company's research is centered on compounds that promise enhanced efficacy and safety, positioning Euclises as a significant player in the pharmaceutical industry. It operates out of the BioGenerator Accelerator Labs, fostering a collaborative environment for its innovative pursuits.

Confluence Life Sciences, Inc. is a drug discovery company based in Saint Louis, Missouri, specializing in the design and development of mechanistically novel kinase inhibitors for human and animal health care. Founded in 2010, the company utilizes its KINect technology platform to identify and develop new drugs targeting key enzymes involved in cancer growth, survival, and metastasis, as well as in chronic inflammatory diseases. Confluence Life Sciences distinguishes itself by focusing on novel binding sites and previously undrugged kinases, addressing challenges that other programs have overlooked. The company is supported by a team of experts with extensive pharmaceutical experience in kinase inhibitor discovery and development, enabling it to pursue innovative strategies and targets. Confluence Life Sciences aims to establish scientific and business collaborations to enhance its program pipeline, which follows a cycle of discovery, development, and partnership to meet unmet medical needs.

GeneriCo, LLC is a pharmaceutical company that specializes in the development and marketing of generic medications. Founded in 2013 and headquartered in Saint Louis, Missouri, with additional offices in Bengaluru, India; Italy; and South Korea, GeneriCo focuses on foundational medicines across various therapeutic areas, including cardiovascular health, pain management, central nervous system disorders, oncology, and aging-related conditions. The company distinguishes itself by targeting niche generic pharmaceuticals that have been overlooked by larger competitors, particularly those that involve complex formulations and innovative drug delivery technologies. This strategic focus allows GeneriCo to address specific market needs that are often neglected by mid-sized and large generic companies. GeneriCo serves a global customer base, providing essential medications that contribute to improved health outcomes.

SanusEO, LLC is a St. Louis-based company that specializes in developing a mobile patient engagement platform (PEP) designed to enhance communication and care between patients and healthcare providers. Founded in 2012, the platform employs data analytics to deliver daily alerts and real-time participant data to care teams, facilitating timely interventions for chronic disease management. SanusEO offers targeted programs such as transition care for patients recently discharged from hospitals and bootcamps for newly diagnosed or at-risk individuals. The platform promotes behavior modification in key health areas, including medication adherence, vital monitoring, diet, and physical activity, with capabilities for multi-language support. By streamlining engagement and intervention processes, SanusEO aims to improve patient outcomes while reducing healthcare costs.

Moblico is a developer of a digital marketing platform tailored for wholesale distributors, manufacturers, and contractors. The company focuses on enhancing customer service and facilitating order processing while helping clients expand their customer base. Its platform provides comprehensive product information and utilizes mobile applications, texting, and geo-targeted technologies to improve service efficiency and convenience. By leveraging these tools, Moblico enables its clients to effectively engage with their customers, retain their loyalty, and maximize monetization opportunities. The company's technology and mobile expertise are designed to ensure that clients can communicate with the right customers at the right time, ultimately driving better returns for their mobile applications.

CoverCress Inc. specializes in developing and commercializing field pennycress as a sustainable oilseed crop for industrial oils and livestock feed. Founded in 2013, the company is headquartered in Saint Louis, Missouri.

Threater delivers a comprehensive cybersecurity platform focused on active network defense. The system automates the discovery, enforcement, and analysis of cyber threats at scale, enabling organizations to detect and neutralize risks proactively and automatically. Its patented technology blocks all known threats, allowing the rest of the security stack to operate more efficiently. By integrating threat detection, enforcement, and response into a single solution, Threater helps enterprises safeguard their networks and data against evolving cyber threats.

BenchmarkONE is a St. Louis, Missouri-based company that specializes in developing sales and marketing automation software for small and mid-sized businesses. Founded in 2010 and previously known as Hatchbuck, Inc., BenchmarkONE provides an all-in-one customer relationship management (CRM) platform that includes features for sales automation, real-time activity monitoring, and email marketing. Its user-friendly interface allows businesses to create and manage campaigns, track leads, and analyze performance metrics effectively. The software is designed to streamline the sales process, enhance customer engagement, and facilitate the growth of relationships into sales. As of June 2020, BenchmarkONE operates as a subsidiary of Benchmark Internet Group, LLC.

RoverTown is a company that specializes in developing branded applications for convenience retailers, aimed at enhancing customer engagement in a digital landscape. By providing a versatile platform, RoverTown enables retailers to easily implement mobile coupon acceptance, manage coupon campaigns, and run loyalty programs, all while ensuring seamless integration with point-of-sale systems. The company distinguishes itself from competitors by offering flexibility in integrating with various technology vendors and by delivering robust implementation and support services. This innovative approach allows businesses to strengthen their connection with consumers and drive sales growth effectively.

SynerZ Medical, Inc. develops medical device for the treatment of obesity and type 2 diabetes. The company was incorporated in 2013 and is based in St. Louis, Missouri.

PFITR, Inc. is a technology company headquartered in Chesterfield, Missouri, specializing in integrated mobile solutions for public funds investment managers. Founded in 2013, PFITR offers a software-as-a-service platform designed to assist public fiduciaries—such as treasurers and directors of finance—in managing trillions of taxpayer dollars. Its flagship product, the Bond Price Validation Tool, provides users with essential valuation metrics derived from market transactions, enabling informed investment decisions while adhering to mandates of safety, liquidity, and yield. The software enhances transparency by offering analytics and internal controls that mitigate risks associated with hidden commissions and poor timing in investment purchases. By leveraging proprietary data from recognized partners, PFITR aims to empower public fiduciaries to optimize their portfolios and ensure accountability to constituents and auditors. The company has garnered interest from early-stage investors and is actively building its customer base, targeting a significant penetration of U.S. public entities over the coming years.

ImmunoPhotonics, Inc. is a biotechnology company focused on developing innovative immunotherapy-based treatments for cancer, specifically targeting metastatic solid tumors. Founded in 2008 and headquartered in Columbia, Missouri, the company has created a proprietary drug product that functions as a minimally invasive autologous cancer vaccine. This treatment involves the intratumoral injection of a carbohydrate polymer following tumor ablation, which harnesses the immune system's response to tumor-associated neoantigens released during the process. By doing so, ImmunoPhotonics aims to generate a systemic anti-tumor immune response, facilitating the treatment of late-stage metastatic cancers. The company has established a strategic partnership with Veterinary Cancer Therapeutics, LLC, enhancing its potential for clinical application.