IndieBio

IndieBio is an accelerator firm established in 2014 and based in San Francisco, California, with an additional office in New York. It specializes in startups that utilize synthetic biology to address significant global challenges. IndieBio runs four-month accelerator programs aimed at both companies and teams with innovative ideas, focusing on seed-stage and early-stage investments. The firm typically invests $250,000, providing $50,000 in exchange for eight percent equity in biotech startups, with the possibility of an additional $25,000 as a convertible loan note. IndieBio prioritizes investments in businesses that leverage biology as the core of their technology, particularly in life sciences, biotechnology, and related fields. The firm favors teams with a minimum of two co-founders and is open to investing in startups from various geographical locations.

Alexander Hall-Daniels

Associate

418 past transactions

Beeflow

Convertible Note in 2023
Beeflow S.A. is a company that specializes in professional pollination services, focusing on the enhancement of bee health and efficiency. Founded in 2016 and headquartered in Buenos Aires, Argentina, Beeflow employs scientific techniques and organic compounds to improve the immune systems of bees, enabling them to effectively pollinate specific crops. The company has demonstrated significant success in increasing crop yields, with reported improvements ranging from 20% to 90% in various fruits such as blueberries, almonds, raspberries, and kiwifruit. Since its inception, Beeflow has expanded its operations to the United States and continues to grow its presence, particularly in Ventura County, California. The company's efforts aim to address the challenges of declining bee populations while supporting agricultural productivity.

Cayuga Biotech

Seed Round in 2023
Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayuga is developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.

DNALite Therapeutics

Convertible Note in 2023
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.

Re-Fresh Global

Seed Round in 2023
Provider of textile waste management technology intended to solve the problem of textile waste with a patented method. The company initiates and implements circular economy projects, training, and international cooperation programs, enabling users to use smart collection, separation, and low-cost upcycling of large volumes of low-value textile waste.

Mirá Biotech

Seed Round in 2022
Mirá Biotech is a biotechnology company focused on the development of sustainable, formaldehyde-free engineered wood products. By utilizing waste materials, such as sugar cane bagasse, the company aims to create all-natural alternatives to traditional wood boards, thereby promoting a circular economy. This innovative approach not only eliminates the need for tree harvesting but also contributes to sustainable industrial practices, positioning Mirá Biotech as a leader in environmentally friendly manufacturing solutions.

MAA'VA

Seed Round in 2022
MAA'VA focuses on recycling plastic to create sustainable building materials that can replace traditional concrete. The company aims to address environmental challenges such as plastic waste, water scarcity, and climate change by developing eco-friendly materials from recycled plastics and upcycled manufacturing waste. By incorporating carbon sequestration techniques, MAA'VA produces durable construction materials that cater to the growing demand for housing while promoting sustainable practices. Their offerings support both conventional and 3D printing construction methods, providing clients with innovative solutions that contribute to a greener future.

BioLumen

Convertible Note in 2022
BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.

Pannex Therapeutics

Seed Round in 2022
Pannex Therapeutics is a scientifically-based pharmaceutical company that develops new drugs to treat chronic musculoskeletal pain. was founded in 2020.

Minus Materials

Convertible Note in 2022
Minus Materials uses microalgae to produce CO2-storing biominerals for the cement and concrete industry. The company was founded to support sustainability and innovation in cement and concrete manufacturing.

Joywell Foods

Series B in 2022
Derived from exotic plants, protein sweeteners are rare compounds that provide an amazing taste without the calories.

Voyage Foods

Series A in 2022
Voyage Foods has made sustainable and scalable alternatives to foods that have current obstacles –environmental, social, and health alike. Our breakthrough technology provides endless opportunities to make delicious, nearly identical, versions of beloved foods, without compromising individual health or our planet. We replicated the world’s favorite foods so that we can all enjoy them, forever.

ClimateCrop

Seed Round in 2022
ClimateCrop technologies allow plants to store more carbon and energy, resulting in increased yields in biomass or fruit states. Founded in 2021 and is based in Ness Ziona.

AnimalBiome

Series A in 2022
AnimalBiome focuses on improving the gut health of dogs and cats in the United States that suffer from chronic digestive disorders. The company offers microbiome-based supplements and non-invasive diagnostic tools designed to identify imbalances in the gut microbiome. Utilizing deoxyribonucleic acid sequencing, AnimalBiome's diagnostic services assess the balance of gut bacteria, allowing pet owners to gain insights into their pets' gut health. This information enables tailored supplementation aimed at restoring gut balance, ultimately promoting a healthier and happier life for pets.

UPSIDE Foods

Series C in 2022
UPSIDE Foods, formerly known as Memphis Meats, is a company headquartered in San Francisco, California, that specializes in producing cultured meat directly from animal cells. Founded in 2015 by Uma Valeti and Nicholas Genovese, the company focuses on developing products such as hot dogs, sausages, burgers, and meatballs without the need to raise and slaughter animals. This innovative approach to meat production requires significantly less caloric input, water, land, and energy compared to traditional methods, while also aiming to provide consumers with cleaner meat products that are free from harmful chemicals.

DNALite Therapeutics

Venture Round in 2022
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.

Eachday

Convertible Note in 2022
Eachday is a digital health management company based in Pittsburgh, Pennsylvania, focused on providing tools and evidence-based techniques for self-managing ADHD. The company's application leverages data and neuroscience to assist users in tracking their behaviors and interests, including task completion, cognitive failures, and self-reported symptoms. By creating personalized profiles for users, Eachday aims to enhance understanding of their condition, visualize time, and develop effective routines. This approach enables individuals to address ADHD symptoms as they arise and alleviate the cognitive load associated with daily activities.

Conan MedTech

Seed Round in 2022
Conan MedTech, founded in 2020 and based in Ithaca, New York, specializes in the development of rapid point-of-care diagnostic tests for concussions. The company's innovative system is designed to facilitate real-time concussion detection, enabling sports medicine doctors, athletic coaches, and trainers to make informed decisions during games. By providing advanced and efficient medical assistance, Conan MedTech aims to enhance the diagnosis of mild traumatic brain injuries, ultimately improving patient care and outcomes.

Conan MedTech

Convertible Note in 2022
Conan MedTech, founded in 2020 and based in Ithaca, New York, specializes in the development of rapid point-of-care diagnostic tests for concussions. The company's innovative system is designed to facilitate real-time concussion detection, enabling sports medicine doctors, athletic coaches, and trainers to make informed decisions during games. By providing advanced and efficient medical assistance, Conan MedTech aims to enhance the diagnosis of mild traumatic brain injuries, ultimately improving patient care and outcomes.

OzoneBio

Seed Round in 2022
OzoneBio is a cleantech company that focuses on lignocellulosic waste-derived bio-plastics production. In its workflow, they utilize the unique technology of dead cell fermentation («Zombie cells») that allows them to convert challenging/toxic feedstocks into high-value products and avoid significant expenses and complications related to live-cell fermentation. OzoneBio was founded in 2021 and is headquartered in Toronto, Canada.

Innatrix

Convertible Note in 2022
Innatrix is an agricultural biotechnology company focused on developing innovative biological and chemical products aimed at controlling challenging crop diseases, pests, and weeds. Utilizing patented protein evolution technology, the company has created a peptide and RNA interference (RNAi) delivery platform that offers eco-friendly alternatives for crop protection. Innatrix's proprietary automated platform allows for advanced protein engineering through continuous laboratory evolution and other methods, such as phage display. This technology enhances researchers' capabilities in control, reporting, recording, simulation, and remote access, positioning Innatrix as a leader in sustainable agricultural solutions.

Innatrix

Seed Round in 2022
Innatrix is an agricultural biotechnology company focused on developing innovative biological and chemical products aimed at controlling challenging crop diseases, pests, and weeds. Utilizing patented protein evolution technology, the company has created a peptide and RNA interference (RNAi) delivery platform that offers eco-friendly alternatives for crop protection. Innatrix's proprietary automated platform allows for advanced protein engineering through continuous laboratory evolution and other methods, such as phage display. This technology enhances researchers' capabilities in control, reporting, recording, simulation, and remote access, positioning Innatrix as a leader in sustainable agricultural solutions.

LizarBio Therapeutics

Pre Seed Round in 2022
PluriCell wants to positively impact the lives of millions of patients suffering from chronic heart failure condition by injecting healthy bona fide lab-made human heart cells in their failing heart, improve its function and, ultimately, the clinical outcome of the patients. Our tech enables us not only tackle heart diseases, but potentially, many chronic disorders currenly untractable.

Lypid

Seed Round in 2022
Minutri brings together a healthy, practical, tasty food, ready for consumption, and for all tastes, ages, food preferences, and times of the day. From breakfast to supper, they have ready meals, snacks, supplements, and drinks, with vegan, organic, zero sugar, low carb, and other options. The company's foods are developed with the aim of being balanced, nutritious, and very tasty. They are gluten-free and dairy-free, made with natural and selected ingredients and spices, without refined sugar, without preservatives or artificial additives.

Finless Foods

Series B in 2022
Finless Foods Inc. is a biotechnology company based in Emeryville, California, focused on producing sustainable seafood alternatives through cellular agriculture technologies. Founded in 2017, the company specializes in growing marine-animal cells to create seafood products, including bluefin tuna. Finless Foods aims to provide a healthier and environmentally friendly alternative to traditionally caught and farmed seafood, offering consumers a cost-effective option that does not compromise on taste or dietary preferences. The company's mission is to develop and mass manufacture innovative marine animal food products that promote sustainability and accessibility in the seafood market.

QuantumCyte

Convertible Note in 2022
QuantumCyte, Inc. is a biotechnology company based in Sunnyvale, California, founded in 2014. It specializes in developing a cell analysis system designed to enhance drug efficacy predictions and advance cancer research. By analyzing large numbers of cells, QuantumCyte aims to deepen the understanding of immune system and cancer biology. The company utilizes artificial intelligence in its pathology technology platform to provide precise cellular data, facilitating single-cell analysis for healthcare providers. Its team comprises experts from various fields, including biology, high technology, and diagnostics, with backgrounds in esteemed organizations such as Stanford and Genentech. QuantumCyte has established strong collaborations with specialists in cancer and genomic sequencing to meet fundamental research needs and ensure the scalability of its products.

Lypid

Seed Round in 2022
Minutri brings together a healthy, practical, tasty food, ready for consumption, and for all tastes, ages, food preferences, and times of the day. From breakfast to supper, they have ready meals, snacks, supplements, and drinks, with vegan, organic, zero sugar, low carb, and other options. The company's foods are developed with the aim of being balanced, nutritious, and very tasty. They are gluten-free and dairy-free, made with natural and selected ingredients and spices, without refined sugar, without preservatives or artificial additives.

Avisa Myko

Convertible Note in 2022
Avisa Myko Inc. is a biotechnology company based in San Francisco, California, that specializes in the production of natural soluble melanin through precision fermentation technology. This innovative approach allows the company to manufacture melanin at scale and at an affordable cost, ensuring high purity and ease of application across various industries. Avisa Myko's melanin serves multiple purposes, including protection against ionizing radiation and electricity generation, and is utilized in cosmetics, biomedicine, organic semiconductors, biosensors, and textiles. The company is also developing a prototype sunscreen that leverages its melanin as an ultraviolet blocker without relying on conventional chemical or mineral filters. Through its patented technology, Avisa Myko aims to improve human health and environmental sustainability by integrating melanin into products such as latex, fabrics, and laminated materials.

AromatEco

Convertible Note in 2022
AromatEco assists household brands in becoming more environmentally friendly by delivering renewable flavors and perfumes. Headquartered in London, UK.

NovoNutrients

Convertible Note in 2022
NovoNutrients is focused on converting industrial waste carbon dioxide emissions into high-value protein ingredients for food and animal feed. The company has developed a fermentation platform that utilizes proprietary microbes and advanced gas fermentation systems to transform CO2, along with hydrogen and oxygen, into complete and safe single-cell protein. This innovative approach not only provides sustainable protein sources to support a growing population but also plays a role in combating climate change through carbon capture and utilization. By addressing both food security and environmental sustainability, NovoNutrients aims to meet the increasing demand for alternative protein solutions.

AromatEco

Seed Round in 2022
AromatEco assists household brands in becoming more environmentally friendly by delivering renewable flavors and perfumes. Headquartered in London, UK.

Endless West

Series C in 2022
Endless West is a beverage startup using scientific production methods to create its own original blend of wines and spirits. Its winery uses molecules from plants, animals, and substances for taste, smell, and color and combines them to create sustainable wine without any grapes, yeast, or any kind of fermentation. The company's first product, Glyph, is the first aged-style spirit made using flavor and aroma molecules extracted from more efficient sources in nature. Glyph is made without aging or barreling which means significantly less wood, water, and land is used in its production process. Endless West was founded in 2015 and is headquartered in San Francisco, California.

ArgenTAG

Pre Seed Round in 2022
ArgenTAG specializes in developing synthetic DNA barcoding technology aimed at enhancing the capabilities of long-read sequencing applications in genomics. By addressing the limitations associated with reduced multiplexing capacity and sequencing throughput, ArgenTAG enables the simultaneous analysis of thousands of samples. The company integrates advanced micro-fabrication techniques with next-generation DNA sequencing and molecular biology, leveraging reengineered error correction technologies initially derived from digital communications. This innovative approach facilitates the decentralization of genome sequencing, allowing medical professionals to effectively analyze antibodies and perform single-cell sequencing, thus advancing the field of personalized medicine.

Nat4Bio

Seed Round in 2022
At NAT4Bio, we develop naturally-sourced coatings that protect produce from spoilage and decay. By leveraging microbial fermentation of selected fungi & bacteria and through carefully designed downstream processes, we obtain cell-free compounds, meaning we use microbes' active principles without the microbes themselves. Our first product is a natural and edible coating for fresh lemons that could potentially replace the combination of waxes and chemical fungicides. We are also prototyping formulations for blueberries and avocados, and we aim to expand our portfolio to address the needs of every fruit class.

Nat4Bio

Convertible Note in 2022
At NAT4Bio, we develop naturally-sourced coatings that protect produce from spoilage and decay. By leveraging microbial fermentation of selected fungi & bacteria and through carefully designed downstream processes, we obtain cell-free compounds, meaning we use microbes' active principles without the microbes themselves. Our first product is a natural and edible coating for fresh lemons that could potentially replace the combination of waxes and chemical fungicides. We are also prototyping formulations for blueberries and avocados, and we aim to expand our portfolio to address the needs of every fruit class.

ArgenTAG

Convertible Note in 2022
ArgenTAG specializes in developing synthetic DNA barcoding technology aimed at enhancing the capabilities of long-read sequencing applications in genomics. By addressing the limitations associated with reduced multiplexing capacity and sequencing throughput, ArgenTAG enables the simultaneous analysis of thousands of samples. The company integrates advanced micro-fabrication techniques with next-generation DNA sequencing and molecular biology, leveraging reengineered error correction technologies initially derived from digital communications. This innovative approach facilitates the decentralization of genome sequencing, allowing medical professionals to effectively analyze antibodies and perform single-cell sequencing, thus advancing the field of personalized medicine.

Sóliome

Seed Round in 2022
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Sóliome

Convertible Note in 2022
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Cayuga Biotech

Seed Round in 2022
Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayuga is developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.

Ceragen

Convertible Note in 2022
Ceragen is a biotechnology company based in Kitchener, Ontario, focused on enhancing agricultural productivity through plant microbiome engineering. The company specializes in precision microbiome engineering, offering inoculant products specifically designed for controlled environment agriculture. These products aim to provide farmers with natural solutions that enhance crop yields, allowing them to grow more food in smaller spaces. By improving plants' resilience to environmental stressors, Ceragen's innovations support sustainable farming practices and contribute to the efficient use of land resources, addressing the growing need to feed the global population.

Capra Biosciences

Convertible Note in 2022
Capra Biosciences is a biotechnology company harnessing biology for efficient and low-carbon production of everyday chemicals. It develops bioreactor technology designed to make the production of chemical products more efficient. The company developed a biofilm bioreactor which has the potential to significantly reduce the downstream processing requirements and costs inherent in the bio-manufacturing of products such as fuels. Capra Biosciences was founded in 2020 and is headquartered in Alexandria, VA.

Cellens

Seed Round in 2022
Cellens is a spinoff company from Tufts University focused on enhancing cancer screening through noninvasive methods. The company has developed a cell surface scanning platform aimed at assisting oncologists in the detection of bladder cancer. Utilizing atomic force microscopy imaging combined with machine learning, Cellens' technology analyzes physio-biomarkers on cell surfaces derived from urine samples. This innovative approach generates a diagnostics score for bladder cancer, enabling healthcare providers, including oncologists and urologists, to minimize the need for invasive and costly diagnostic procedures. By improving the accuracy of bladder cancer detection, Cellens aims to optimize the patient experience and increase survival rates.

Cellens

Convertible Note in 2022
Cellens is a spinoff company from Tufts University focused on enhancing cancer screening through noninvasive methods. The company has developed a cell surface scanning platform aimed at assisting oncologists in the detection of bladder cancer. Utilizing atomic force microscopy imaging combined with machine learning, Cellens' technology analyzes physio-biomarkers on cell surfaces derived from urine samples. This innovative approach generates a diagnostics score for bladder cancer, enabling healthcare providers, including oncologists and urologists, to minimize the need for invasive and costly diagnostic procedures. By improving the accuracy of bladder cancer detection, Cellens aims to optimize the patient experience and increase survival rates.

Unlocked Labs

Seed Round in 2021
Solving gout using engineered probiotics

Veloz Bio

Convertible Note in 2021
Veloz Bio is a biotechnology company established in 2021 and located in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture sustainable and affordable animal-free and alternative proteins. By leveraging efficient plant metabolism, Veloz Bio has created a rapid protein production system that enables scalable growth of new proteins. This innovation allows biotech firms to gain expertise in essential areas of protein production, including supercritical fluid extraction and membrane purification. Through its focus on alternative proteins, Veloz Bio aims to contribute to a more sustainable food supply.

Unlocked Labs

Convertible Note in 2021
Solving gout using engineered probiotics

Veloz Bio

Seed Round in 2021
Veloz Bio is a biotechnology company established in 2021 and located in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture sustainable and affordable animal-free and alternative proteins. By leveraging efficient plant metabolism, Veloz Bio has created a rapid protein production system that enables scalable growth of new proteins. This innovation allows biotech firms to gain expertise in essential areas of protein production, including supercritical fluid extraction and membrane purification. Through its focus on alternative proteins, Veloz Bio aims to contribute to a more sustainable food supply.

ClimateCrop

Seed Round in 2021
ClimateCrop technologies allow plants to store more carbon and energy, resulting in increased yields in biomass or fruit states. Founded in 2021 and is based in Ness Ziona.

ClimateCrop

Convertible Note in 2021
ClimateCrop technologies allow plants to store more carbon and energy, resulting in increased yields in biomass or fruit states. Founded in 2021 and is based in Ness Ziona.

Zymochem

Seed Round in 2021
ZymoChem, Inc. develops microbes and bioprocesses that enable production of chemicals from renewable sources, such as sugars. The company was founded in 2013 and is based in Emeryville, California.

Gatehouse Bio

Seed Round in 2021
Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on advancing precision medicine through the development of targeted therapeutics. Founded in 2016, the company utilizes a novel bioinformatics platform to identify small ribonucleic acid (sRNA) biomarkers, which are essential for uncovering disease signatures and facilitating drug discovery and repurposing. Their technology employs machine learning to achieve high accuracy in classifying patient samples, making it a valuable tool for identifying custom biomarker panels tailored to individual needs. Gatehouse Bio collaborates with leading drug developers to discover novel drug targets and develop companion diagnostics, with applications validated in areas such as cardiology, neurology, oncology, respiratory diseases, and rare diseases.

Tidal Vision

Venture Round in 2021
Tidal Vision Inc. is a company based in Ferndale, Washington, that focuses on manufacturing sustainable products derived from ocean waste, such as salmon skin and discarded crab shells. Founded in 2015, Tidal Vision offers a range of innovative products, including Alaska Salmon leather items like wallets, belts, shoes, and boots. Additionally, the company produces a variety of chitin and chitosan-based products, which serve multiple purposes, such as a fining agent for clarifying beverages, water treatment solutions, and antimicrobial applications. Other offerings include Crystal Clarity, a water clarifier for pools and spas, Game Meat Protector to prevent spoilage, High Tide, a natural shellfish extract, Tidal Grow, an all-purpose plant food, and Tidal Scrub, a sponge designed to eliminate germs and odors. Through its commitment to sustainability, Tidal Vision is positioned at the intersection of biotechnology and manufacturing.

Solid Ox Motors

Seed Round in 2021
Solid Ox Motors offers carbon-neutral onboard generators for battery electric vehicle.

Grand Bio

Seed Round in 2021
Grand Bio is working to improve the efficiency with which cells create their own growth factors. The firm provides supplements that boost growth factors in the medium in which cells live and thrive.

Grand Bio

Convertible Note in 2021
Grand Bio is working to improve the efficiency with which cells create their own growth factors. The firm provides supplements that boost growth factors in the medium in which cells live and thrive.

Pyrone Systems

Seed Round in 2021
Pyrone Systems develops biopesticides that combine biology with chemistry. The company was founded in 2021.

Pyrone Systems

Convertible Note in 2021
Pyrone Systems develops biopesticides that combine biology with chemistry. The company was founded in 2021.

Lingrove

Series A in 2021
Lingrove, LLC, founded in 2014 and based in San Francisco, California, specializes in manufacturing bio-composite materials aimed at addressing the diminishing supply of traditional wood. The company produces Ekoa, a high-performance natural fiber composite made from flax linen fibers and resin derived from industrial waste. Ekoa is utilized in various applications, including the production of guitars and other musical instruments, as well as in commercial interiors, transportation, and construction. Lingrove's innovative products are designed to mimic the appearance of wood while being plant-based and non-wood, thereby contributing to the reduction of deforestation and minimizing embodied carbon in buildings. By offering sustainable, carbon-negative solutions, Lingrove supports industries such as furniture, transportation, music, and sports in creating products that meet performance standards while promoting environmental responsibility.

New Culture

Series A in 2021
New Culture Inc. is a food and beverage company that specializes in producing cheese from protein using innovative methods. By employing microflora to create dairy proteins and dairy products, the company aims to revolutionize traditional cheese-making processes. Founded in 2018 and headquartered in San Francisco, California, New Culture is committed to developing sustainable and alternative cheese options that appeal to a growing market of health-conscious and environmentally aware consumers.

Sundial Foods

Seed Round in 2021
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.

Proton Intelligence

Seed Round in 2021
Proton Intelligence, founded in 2020 and headquartered in Vancouver, Canada, specializes in biomarker monitoring to manage chronic diseases, particularly hyperkalemia, which involves high potassium levels. The company operates a wearable platform that delivers accurate and real-time potassium measurements through interstitial fluid from the skin, providing data closely correlated to blood levels. This innovation is crucial for heart and kidney care, as it enables clinicians and patients to monitor potassium levels effectively. By facilitating timely and informed decision-making regarding medications, diet, and treatment options, Proton Intelligence aims to enhance health outcomes and improve the quality of life for individuals living with chronic conditions.

Prothegen

Seed Round in 2021
Prothegen is a biotechnology company that develops cutting-edge medicines for precisely regulating cell death. The company is based in Palo Alto, California.

Prothegen

Convertible Note in 2021
Prothegen is a biotechnology company that develops cutting-edge medicines for precisely regulating cell death. The company is based in Palo Alto, California.

California Cultured

Seed Round in 2021
California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Kyomei

Seed Round in 2021
Kyomei is a company based in Oxford, England, that focuses on developing a plant-based production system aimed at creating animal proteins for the alternative meat industry. Founded in 2021, Kyomei utilizes plant cell biology to enhance the flavor of meat alternatives by scaling the production of myoglobin in plants, which contributes to the umami taste. This innovative approach not only aims to improve the sensory experience of plant-based meats but also seeks to reduce the environmental impact associated with traditional animal farming. By providing consumers with flavorful plant-based meat options, Kyomei positions itself as a key player in the growing alternative meat market.

PunaBio

Pre Seed Round in 2021
PunaBio is a Buenos Aires-based company that develops biological products aimed at enhancing agricultural productivity through environmentally friendly methods. By utilizing extremophile microorganisms, PunaBio focuses on improving crop nutrition, which contributes to increased yields and better crop quality. Their products are designed to enable farmers to cultivate crops on degraded soils and restore and enrich agricultural land sustainably. This approach not only helps improve farmers' productivity but also promotes sustainable agricultural practices.

New Age Meats

Series A in 2021
New Age Meats is a biotechnology company based in San Francisco, California, founded in 2017. The company specializes in producing cultivated meat using an automated, data-driven platform and advanced stem cell technology. By growing meat from animal cells rather than relying on traditional animal slaughter, New Age Meats aims to create healthier and more sustainable meat alternatives.

Plantruption

Seed Round in 2021
Plantruption builds a brand of sustainability to develop products using seaweed and microalgae. The company is on a mission to create the first plant-based seafood. It researches and collaborates with universities and food technologists to provides Plant-based seafood that’s close in taste and texture to the real deal. Plant-based seafood provides a host of environmental benefits, including alleviating pressures on rapidly depleting fisheries, providing relief to fragile ocean ecosystems, reducing the impact of fishing nets on the ocean plastic problem, and reducing production emissions. The company was founded in 2019 in Dublin, Dublin.

Kutanios

Seed Round in 2021
Kutanios is a biotechnology firm focused on creating new compounds for anti-aging, sun care, anti-acne, and skin cleaning items. Headwuartered in London.

Finless Foods

Convertible Note in 2021
Finless Foods Inc. is a biotechnology company based in Emeryville, California, focused on producing sustainable seafood alternatives through cellular agriculture technologies. Founded in 2017, the company specializes in growing marine-animal cells to create seafood products, including bluefin tuna. Finless Foods aims to provide a healthier and environmentally friendly alternative to traditionally caught and farmed seafood, offering consumers a cost-effective option that does not compromise on taste or dietary preferences. The company's mission is to develop and mass manufacture innovative marine animal food products that promote sustainability and accessibility in the seafood market.

Beeflow

Series A in 2021
Beeflow S.A. is a company that specializes in professional pollination services, focusing on the enhancement of bee health and efficiency. Founded in 2016 and headquartered in Buenos Aires, Argentina, Beeflow employs scientific techniques and organic compounds to improve the immune systems of bees, enabling them to effectively pollinate specific crops. The company has demonstrated significant success in increasing crop yields, with reported improvements ranging from 20% to 90% in various fruits such as blueberries, almonds, raspberries, and kiwifruit. Since its inception, Beeflow has expanded its operations to the United States and continues to grow its presence, particularly in Ventura County, California. The company's efforts aim to address the challenges of declining bee populations while supporting agricultural productivity.

Diadem Biotherapeutics

Convertible Note in 2021
Diadem Biotherapeutics is a biotechnology company that focuses on creating bio-therapeutical materials produced using organic means. Diadem develops exosomes to treat chronic inflammatory and auto-immune conditions.

QuantumCyte

Convertible Note in 2021
QuantumCyte, Inc. is a biotechnology company based in Sunnyvale, California, founded in 2014. It specializes in developing a cell analysis system designed to enhance drug efficacy predictions and advance cancer research. By analyzing large numbers of cells, QuantumCyte aims to deepen the understanding of immune system and cancer biology. The company utilizes artificial intelligence in its pathology technology platform to provide precise cellular data, facilitating single-cell analysis for healthcare providers. Its team comprises experts from various fields, including biology, high technology, and diagnostics, with backgrounds in esteemed organizations such as Stanford and Genentech. QuantumCyte has established strong collaborations with specialists in cancer and genomic sequencing to meet fundamental research needs and ensure the scalability of its products.

Plantruption

Convertible Note in 2021
Plantruption builds a brand of sustainability to develop products using seaweed and microalgae. The company is on a mission to create the first plant-based seafood. It researches and collaborates with universities and food technologists to provides Plant-based seafood that’s close in taste and texture to the real deal. Plant-based seafood provides a host of environmental benefits, including alleviating pressures on rapidly depleting fisheries, providing relief to fragile ocean ecosystems, reducing the impact of fishing nets on the ocean plastic problem, and reducing production emissions. The company was founded in 2019 in Dublin, Dublin.

Ceragen

Convertible Note in 2021
Ceragen is a biotechnology company based in Kitchener, Ontario, focused on enhancing agricultural productivity through plant microbiome engineering. The company specializes in precision microbiome engineering, offering inoculant products specifically designed for controlled environment agriculture. These products aim to provide farmers with natural solutions that enhance crop yields, allowing them to grow more food in smaller spaces. By improving plants' resilience to environmental stressors, Ceragen's innovations support sustainable farming practices and contribute to the efficient use of land resources, addressing the growing need to feed the global population.

Ceragen

Seed Round in 2021
Ceragen is a biotechnology company based in Kitchener, Ontario, focused on enhancing agricultural productivity through plant microbiome engineering. The company specializes in precision microbiome engineering, offering inoculant products specifically designed for controlled environment agriculture. These products aim to provide farmers with natural solutions that enhance crop yields, allowing them to grow more food in smaller spaces. By improving plants' resilience to environmental stressors, Ceragen's innovations support sustainable farming practices and contribute to the efficient use of land resources, addressing the growing need to feed the global population.

Intrinsic Medicine

Convertible Note in 2021
Inflammatory disease affects us all. We looked 300 million years into our past to imagine a healthier future, beyond the limitations of today’s anti-inflammatory drugs. Lupa Bio is developing an entirely new class of safer, anti-inflammatory therapeutics based on compounds found in mothers’ milk ...because no technology today can screen like the forces of nature. ​

Jointechlabs

Pre Seed Round in 2021
JointechLabs, Inc. is a company focused on enhancing access to cell-based therapies for healthcare providers and patients. Based in Mount Prospect, Illinois, the company has developed the Mini-Stem System, a closed disposable kit designed for the processing and extraction of stromal vascular cell fractions from human tissue. This innovative medical device allows for the efficient preparation of high-quality injectable fat grafts and fat-derived stem cells, facilitating on-site access to optimized adipose-derived stromal cells (ADSC). By streamlining the process of individualized cell and tissue-based therapies, JointechLabs aims to make these advanced treatments more accessible and cost-effective for use in hospitals, clinics, and local medical offices. Since its incorporation in 2012, the company has been dedicated to improving the efficacy and availability of cell therapies in clinical settings.

Oralta

Seed Round in 2021
Oralta is a U.S.-based company that specializes in the manufacture of probiotic supplements aimed at improving oral health. Its flagship product, FRESH BREATH, consists of chewable tablets designed to combat bad breath by eliminating odor-causing bacteria while promoting the growth of beneficial probiotic strains. The tablets work by preventing the buildup of harmful germs, reducing their growth, and inactivating the byproducts responsible for unpleasant odors. Oralta's innovative approach focuses on restoring a healthy balance of oral bacteria, ultimately enhancing overall oral hygiene and addressing conditions such as tooth decay and gum disease.

PouchNATION

Convertible Note in 2021
PouchNATION is a SaaS company for cashless and guest management solutions digitising the venues and events operations using intelligent NFC wearable technology in Southeast Asia. We aim to empower business owners to operate worry-free in the future.

Ria Health

Convertible Note in 2021
Ria Health is a telehealth provider focused on treating alcohol use disorders through a mobile platform. Founded in 2013 and based in San Francisco, California, the company connects users with addiction specialists for personalized support and guidance. Ria Health employs evidence-based protocols, including medication-assisted treatment, harm reduction, and cognitive behavioral therapy, to assist heavy drinkers seeking to reduce or stop their alcohol consumption. The Ria app facilitates secure, HIPAA-compliant interactions, allowing for video and phone consultations, breathalyzer measurements, and progress tracking. By offering a private and convenient treatment option, Ria Health aims to address the significant gap in care for individuals struggling with alcohol-related issues, ensuring effective and affordable support that aligns with payer objectives.

Stämm

Convertible Note in 2021
Stämm Biotech, founded in 2014 and based in San Francisco, California, specializes in innovative biomanufacturing solutions for the life sciences sector. The company has developed a novel bioproduction system that integrates microfluidics, electroporation, and robotics to address the challenges of scaling in the biotech industry. Stämm's flagship product, the Bioprocessor, is an all-in-one, plug-and-play desktop unit that significantly enhances productivity, being at least 70 times more efficient than conventional bioreactors. Additionally, Stämm offers a suite of products including an automated continuous batch system for microbial growth, tools for tracking biological variations, and systems for monitoring microorganisms to convert data into actionable insights. This technological advancement positions Stämm to unlock a substantial market opportunity in biomanufacturing over the next decade.

AvantGuard

Convertible Note in 2021
Our first product, HaloFilm turns any surface into an antimicrobial surface by holding chlorine from store-bought disinfectants on surfaces in a safe and effective manner for as long as a month. HaloFilm contains a novel polymer that when sprayed on creates a thin transparent film that binds to the surface and to chlorine, at levels equivalent to what you would find in a pool. Chlorine is a universally used as a disinfectant against bacteria, virus and fungi, but has a short effective life. We extend the lifetime and overall utility of chlorine to protect surfaces continuously. Our focus is on high touch surfaces in hospitals, mass transit systems, schools, and more; wherever pathogens spread and endanger human health.

Earnest

Pre Seed Round in 2021
At Earnest Earth, we partner with farmers to turn their agricultural waste into proprietary engineered fertilizer that increases crop yields. By managing waste, we save farmers time, space, and help them generate additional income while making a greener and cleaner world. Our patent-pending bioreactors (agricultural waste converters) use composting (heat: kill pathogens), vermicomposting (earthworms: remove heavy metals, infuse microbes), microbes (microorganisms), and machine learning to engineer biofertilizers that increase crop yields (promoting drought resistance, pathogen suppression, and improving soil quality).

Multus

Convertible Note in 2021
Multus Media enables cultivated meat companies to scale affordably and profitably. We take care of the growth media, so our customers can focus on bringing delicious, sustainable meat to the world. Taking a machine learning-based approach we can design a completely animal-free growth media that is tailored for animal cells. This is particularly useful for the cultivated meat industry where there are needs of high performance at large scale. Multus Media was established in 2019 and is headquartered in London, England.

Sundial Foods

Convertible Note in 2021
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.

Sundial Foods

Seed Round in 2021
Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.

DNALite Therapeutics

Convertible Note in 2021
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.

Vertical Oceans

Seed Round in 2021
Akualogix is an agrifood tech start-up that produces shrimp, whitefish, and seaweeds in high-tech five-story farming systems. The company uses advanced technologies and sustainable practices in urban, vertical aquafarms to produce fresh shrimp, fish, and umibudo. Its vertical oceans combine multi-trophic biology with advanced digital technologies in modular growing habitats efficiently stacked in a vertical tower. Akualogix was established in 2020 and is based in Singapore.

OzoneBio

Convertible Note in 2021
OzoneBio is a cleantech company that focuses on lignocellulosic waste-derived bio-plastics production. In its workflow, they utilize the unique technology of dead cell fermentation («Zombie cells») that allows them to convert challenging/toxic feedstocks into high-value products and avoid significant expenses and complications related to live-cell fermentation. OzoneBio was founded in 2021 and is headquartered in Toronto, Canada.

OzoneBio

Seed Round in 2021
OzoneBio is a cleantech company that focuses on lignocellulosic waste-derived bio-plastics production. In its workflow, they utilize the unique technology of dead cell fermentation («Zombie cells») that allows them to convert challenging/toxic feedstocks into high-value products and avoid significant expenses and complications related to live-cell fermentation. OzoneBio was founded in 2021 and is headquartered in Toronto, Canada.

Prolific Machines

Seed Round in 2021
Gaia Laboratories revolutionizes cell production, creating powerful solutions for the defining challenges of time. The founding principles behind Gaia Laboratories are to combat climate change, enable space-food, and make cell therapy accessible to everyone.

Chronus Health

Convertible Note in 2021
Chronus Health, Inc. is focused on developing a portable diagnostic platform that delivers rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and headquartered in California, the company utilizes advanced microfluidics and semiconductor technology, combined with data analytics, to provide real-time diagnoses within minutes. This handheld device significantly enhances the ability of healthcare providers to access actionable data on-site, thereby improving patient outcomes and reducing the time to care. Chronus Health aims to transform the diagnostic process by enabling immediate treatment decisions based on accurate lab results.

Wayfinder Biosciences

Seed Round in 2021
Wayfinder Biosciences develops biosensors for ultra-high-throughput screening for high-value molecules. The company's PerfectPath biosensors make invisible molecules visible. These biosensors generate fluorescence based on the concentration of the desired small-molecule — allowing quantification of product titer at high-throughput using fast fluorescence measurements. Wayfinder Biosciences was established in 2021 and is headquartered in San Francisco, CA.

Wayfinder Biosciences

Convertible Note in 2021
Wayfinder Biosciences develops biosensors for ultra-high-throughput screening for high-value molecules. The company's PerfectPath biosensors make invisible molecules visible. These biosensors generate fluorescence based on the concentration of the desired small-molecule — allowing quantification of product titer at high-throughput using fast fluorescence measurements. Wayfinder Biosciences was established in 2021 and is headquartered in San Francisco, CA.

Avalo

Seed Round in 2021
Avalo is a biotechnology company focused on enhancing crop resilience through innovative gene discovery and control techniques. By employing interpretable machine learning, Avalo accelerates the identification of genes in plants, thereby facilitating the development of improved agricultural crops. The company's artificial intelligence-based platform is designed to uncover the biological origins of traits essential for future agriculture, such as drought tolerance, water-use efficiency, and nutrient density. This advancement in gene discovery not only aids researchers in validating and predicting crop quality but also addresses the challenges posed by a changing climate, contributing to a healthier and more sustainable agricultural landscape.

Avalo

Convertible Note in 2021
Avalo is a biotechnology company focused on enhancing crop resilience through innovative gene discovery and control techniques. By employing interpretable machine learning, Avalo accelerates the identification of genes in plants, thereby facilitating the development of improved agricultural crops. The company's artificial intelligence-based platform is designed to uncover the biological origins of traits essential for future agriculture, such as drought tolerance, water-use efficiency, and nutrient density. This advancement in gene discovery not only aids researchers in validating and predicting crop quality but also addresses the challenges posed by a changing climate, contributing to a healthier and more sustainable agricultural landscape.

Beemmunity

Pre Seed Round in 2021
Pesticide protection for bees.
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