Spring Mill Venture Partners

Spring Mill Venture Partners is a venture capital firm based in Carmel, Indiana, specializing in seed and early-stage investments in emerging markets. Founded in 2004, the firm primarily targets high-growth sectors, including information technology, healthcare technology, and life sciences. Its investment strategy focuses on companies located in Indiana and the surrounding Midwest region, encompassing states such as Illinois, Kentucky, Michigan, and Ohio. In addition to financial support, Spring Mill Venture Partners aims to provide strategic and tactical assistance to help early-stage companies achieve growth and success.

David B. Wortman

Venture Partner

Past deals in Indiana

SonarMed

Series C in 2017
SonarMed, Inc. provides solutions for the placement and monitoring of endotracheal tubes that are used in patients who cannot breathe on their own. Its SonarMed AirWave is a non invasive, adjunctive device that provides direct, precise, and real time monitoring of endotracheal tube position and function, which aids in detecting potentially dangerous or fatal endotracheal tube conditions. The company was founded in 2005 and is based in Carmel, Indiana.

Scale Computing

Series D in 2012
Scale Computing, Inc. specializes in edge computing, virtualization, and hyperconverged solutions tailored for midsized businesses. Founded in 2007 and headquartered in Indianapolis, Indiana, the company offers its HC3™ platform, which integrates servers, storage, and virtualization into a single, user-friendly system. This all-in-one appliance enhances storage speed and capacity while simplifying datacenter management. HC3 continuously monitors virtual machines and hardware components to ensure application availability and efficiently address infrastructure events. In addition to its core platform, Scale Computing provides services such as infrastructure refresh, virtual-to-virtual migration, physical-to-virtual migration, and disaster recovery solutions. As a result, the company is increasingly favored by IT departments across various industries looking to maintain high availability and scalability of their applications.

SonarMed

Series A in 2010
SonarMed, Inc. provides solutions for the placement and monitoring of endotracheal tubes that are used in patients who cannot breathe on their own. Its SonarMed AirWave is a non invasive, adjunctive device that provides direct, precise, and real time monitoring of endotracheal tube position and function, which aids in detecting potentially dangerous or fatal endotracheal tube conditions. The company was founded in 2005 and is based in Carmel, Indiana.

Scale Computing

Series B in 2010
Scale Computing, Inc. specializes in edge computing, virtualization, and hyperconverged solutions tailored for midsized businesses. Founded in 2007 and headquartered in Indianapolis, Indiana, the company offers its HC3™ platform, which integrates servers, storage, and virtualization into a single, user-friendly system. This all-in-one appliance enhances storage speed and capacity while simplifying datacenter management. HC3 continuously monitors virtual machines and hardware components to ensure application availability and efficiently address infrastructure events. In addition to its core platform, Scale Computing provides services such as infrastructure refresh, virtual-to-virtual migration, physical-to-virtual migration, and disaster recovery solutions. As a result, the company is increasingly favored by IT departments across various industries looking to maintain high availability and scalability of their applications.

Scale Computing

Series A in 2009
Scale Computing, Inc. specializes in edge computing, virtualization, and hyperconverged solutions tailored for midsized businesses. Founded in 2007 and headquartered in Indianapolis, Indiana, the company offers its HC3™ platform, which integrates servers, storage, and virtualization into a single, user-friendly system. This all-in-one appliance enhances storage speed and capacity while simplifying datacenter management. HC3 continuously monitors virtual machines and hardware components to ensure application availability and efficiently address infrastructure events. In addition to its core platform, Scale Computing provides services such as infrastructure refresh, virtual-to-virtual migration, physical-to-virtual migration, and disaster recovery solutions. As a result, the company is increasingly favored by IT departments across various industries looking to maintain high availability and scalability of their applications.

Perfinity

Venture Round in 2008
Perfinity Biosciences, Inc. specializes in developing tools for protein sample preparation. The company's product portfolio includes a range of consumable kits and automated instrument solutions designed to enhance reproducibility and speed in testing. Key offerings encompass immobilized enzymes, affinity reagents, optimized buffers, and software. Notable products include Soluble Smart Digest, a stable trypsin for efficient digestions; Mag Beads tailored for proteomics; QuicPrep, which combines immunoaffinity and trypsin digestion in a single tube; and Flash Digest, an immobilized trypsin reactor for rapid processing. Additionally, Perfinity provides a multi-column Workstation to automate protein separations and mass spectrometry sample preparation. Founded in 2004 and based in West Lafayette, Indiana, the company aims to simplify workflows for a variety of applications, including solid tissues and gels. Perfinity was previously known as QuadraSpec, Inc. before rebranding in March 2010.

CS-Keys

Series A in 2008
CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Biostorage Technologies

Series A in 2007
BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany. Their mission is to provide their clients with world class, biorepository services, exceeding clients’ expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples.

Biostorage Technologies

Venture Round in 2007
BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany. Their mission is to provide their clients with world class, biorepository services, exceeding clients’ expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples.

Perfinity

Series A in 2005
Perfinity Biosciences, Inc. specializes in developing tools for protein sample preparation. The company's product portfolio includes a range of consumable kits and automated instrument solutions designed to enhance reproducibility and speed in testing. Key offerings encompass immobilized enzymes, affinity reagents, optimized buffers, and software. Notable products include Soluble Smart Digest, a stable trypsin for efficient digestions; Mag Beads tailored for proteomics; QuicPrep, which combines immunoaffinity and trypsin digestion in a single tube; and Flash Digest, an immobilized trypsin reactor for rapid processing. Additionally, Perfinity provides a multi-column Workstation to automate protein separations and mass spectrometry sample preparation. Founded in 2004 and based in West Lafayette, Indiana, the company aims to simplify workflows for a variety of applications, including solid tissues and gels. Perfinity was previously known as QuadraSpec, Inc. before rebranding in March 2010.