Spring Mill Venture Partners

Spring Mill Venture Partners is a venture capital firm based in Carmel, Indiana, established in 2004. The firm specializes in seed and early-stage investments, primarily targeting high-growth companies within the information technology, healthcare technology, and life sciences sectors. Its investment focus is on businesses located in Indiana and the surrounding Midwest region, which includes Illinois, Kentucky, Michigan, and Ohio. Spring Mill Venture Partners aims to provide both capital and strategic support to help early-stage companies achieve sustainable growth and success.

Ken Green

Co-Founder and Managing Partner

Past deals in Indiana

Scale Computing

Series D in 2012
Scale Computing provides edge computing, virtualization, and hyperconverged infrastructure solutions for midsized organizations. Its HC3 platform offers an integrated, appliance-based system that combines servers, storage, and virtualization software to deliver a complete data center in a box. HC3 uses self-healing automation to monitor virtual machines, software, and hardware components, detect infrastructure events, and automatically respond to maintain application availability while simplifying data center management. The platform eliminates the need for separate virtualization, disaster recovery, servers, and shared storage by delivering a highly available, easy-to-manage solution that scales with demand. The company supports infrastructure refresh and migrations, including virtual-to-virtual and physical-to-virtual moves, and provides disaster recovery capabilities within a single, unified system. Founded in 2007 and based in Indianapolis, Scale Computing targets small to midmarket and distributed enterprises seeking reduced downtime and simplified IT operations through an integrated, turnkey platform.

Scale Computing

Series B in 2010
Scale Computing provides edge computing, virtualization, and hyperconverged infrastructure solutions for midsized organizations. Its HC3 platform offers an integrated, appliance-based system that combines servers, storage, and virtualization software to deliver a complete data center in a box. HC3 uses self-healing automation to monitor virtual machines, software, and hardware components, detect infrastructure events, and automatically respond to maintain application availability while simplifying data center management. The platform eliminates the need for separate virtualization, disaster recovery, servers, and shared storage by delivering a highly available, easy-to-manage solution that scales with demand. The company supports infrastructure refresh and migrations, including virtual-to-virtual and physical-to-virtual moves, and provides disaster recovery capabilities within a single, unified system. Founded in 2007 and based in Indianapolis, Scale Computing targets small to midmarket and distributed enterprises seeking reduced downtime and simplified IT operations through an integrated, turnkey platform.

Scale Computing

Series A in 2009
Scale Computing provides edge computing, virtualization, and hyperconverged infrastructure solutions for midsized organizations. Its HC3 platform offers an integrated, appliance-based system that combines servers, storage, and virtualization software to deliver a complete data center in a box. HC3 uses self-healing automation to monitor virtual machines, software, and hardware components, detect infrastructure events, and automatically respond to maintain application availability while simplifying data center management. The platform eliminates the need for separate virtualization, disaster recovery, servers, and shared storage by delivering a highly available, easy-to-manage solution that scales with demand. The company supports infrastructure refresh and migrations, including virtual-to-virtual and physical-to-virtual moves, and provides disaster recovery capabilities within a single, unified system. Founded in 2007 and based in Indianapolis, Scale Computing targets small to midmarket and distributed enterprises seeking reduced downtime and simplified IT operations through an integrated, turnkey platform.

Perfinity Biosciences

Venture Round in 2008
Perfinity Biosciences, Inc. is a company focused on advancing protein sample preparation through innovative tools and technologies. Founded in 2004 and located in West Lafayette, Indiana, Perfinity offers a diverse product portfolio that includes immobilized enzymes, affinity reagents, optimized buffers, and software solutions. Key products include Soluble Smart Digest, a stable soluble trypsin for efficient digestions; Mag Beads, designed specifically for proteomics; QuicPrep, which integrates immunoaffinity and trypsin digestion in a single tube; and Flash Digest, an immobilized trypsin reactor for reproducible results. The company also provides a Workstation, a multi-column apparatus that automates protein separations and mass spectrometry sample preparation. Perfinity's solutions are tailored to enhance reproducibility and speed across a variety of workflows, including solid tissues, gels, and sample pellets. The company was previously known as QuadraSpec, Inc. before rebranding in March 2010.

CS-Keys

Series A in 2008
CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Biostorage Technologies

Series A in 2007
BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany. Their mission is to provide their clients with world class, biorepository services, exceeding clients’ expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples.

Biostorage Technologies

Venture Round in 2007
BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany. Their mission is to provide their clients with world class, biorepository services, exceeding clients’ expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples.

Perfinity Biosciences

Series A in 2005
Perfinity Biosciences, Inc. is a company focused on advancing protein sample preparation through innovative tools and technologies. Founded in 2004 and located in West Lafayette, Indiana, Perfinity offers a diverse product portfolio that includes immobilized enzymes, affinity reagents, optimized buffers, and software solutions. Key products include Soluble Smart Digest, a stable soluble trypsin for efficient digestions; Mag Beads, designed specifically for proteomics; QuicPrep, which integrates immunoaffinity and trypsin digestion in a single tube; and Flash Digest, an immobilized trypsin reactor for reproducible results. The company also provides a Workstation, a multi-column apparatus that automates protein separations and mass spectrometry sample preparation. Perfinity's solutions are tailored to enhance reproducibility and speed across a variety of workflows, including solid tissues, gels, and sample pellets. The company was previously known as QuadraSpec, Inc. before rebranding in March 2010.
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