Refactor Capital

Remedy Scientific is a trailblazing company specializing in environmental remediation. It leverages advanced technology, including sensors for pollution assessment, to deliver precise solutions for restoring contaminated land to a safe, productive, and regulatory-compliant state. The company's mission is to transform the way the world addresses environmental contamination, benefiting a wide range of stakeholders.

Pioneering a biologically enhanced future for humanity.

Causal Labs is a technology company that specializes in advanced weather prediction. It develops AI-driven models based on physics to forecast and potentially influence weather patterns, primarily serving the aviation and weather management sectors. These models enable clients to make data-driven decisions, enhance safety, and optimize operations.

MIIST Therapeutics focuses on advancing pulmonary drug delivery systems and digital platforms to improve inhaled drug therapies. The company is developing innovative technology aimed at facilitating smoking cessation and addressing the health risks associated with tobacco use. By creating inhaler technology that targets the deepest areas of the lungs, MIIST enables rapid absorption of medications. This approach aims to enhance the effectiveness of inhaled treatments for various health conditions, starting with smoking addiction, and ultimately seeks to reduce the significant health burdens related to tobacco consumption.

General Galactic is a technology company that produces clean fuel by converting air and waste CO2 into synthetic hydrocarbons using renewable electricity. Its modular hardware systems enable on-site fuel production, making clean energy more accessible and affordable. The company's technology captures and upgrades emissions from various sources, transforming them into renewable hydrocarbon fuels that are compatible with existing infrastructure.

Astranis is a company focused on developing innovative satellite technology designed to deliver data to specific locations on Earth with each satellite it launches. The primary mission of Astranis is to provide high-speed, reliable internet access to underserved regions at a significantly lower cost compared to traditional methods. By doing so, the company aims to bridge the digital divide and connect the approximately 4 billion people worldwide who currently lack internet access, thereby supporting governments and businesses in their efforts to expand global connectivity.

Hexium is a technology company specializing in isotope enrichment, aiming to supply the medical and energy sectors with carbon-free, advanced energy solutions.

Pila Energy manufactures renewable energy equipment to power homes and businesses with sustainable solutions.

Bedrock Materials is a manufacturer specializing in sodium-ion battery materials aimed at transforming energy storage solutions. By pioneering innovative materials and production techniques, the company focuses on reducing the cost of electric vehicles through the commercialization of sodium-ion battery technology. Its electrode materials facilitate large-scale battery production, enabling manufacturers to create electric vehicles with extended ranges and reduced overall battery costs. Bedrock Materials is dedicated to advancing sustainable energy storage for a more environmentally friendly future.

Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing innovative therapies that target senescent cells implicated in age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of therapeutic candidates. These candidates are designed to selectively address senescent cells, as well as pro-inflammatory and pro-fibrotic cell populations that contribute to various chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises industry experts with significant experience in drug development and commercialization across both large pharmaceutical companies and biotech firms.

Orchid is a reproductive technology startup founded in 2019 and headquartered in San Francisco, California. The company specializes in detecting rare genetic disorders through its preconception system, which analyzes the genomes of both partners to assess their genetic predispositions to various common diseases, such as heart disease, Alzheimer’s disease, and breast cancer. Orchid develops its results in collaboration with leading experts in reproductive medicine and genetics, ensuring high accuracy. The company offers a "Couple Report," which utilizes an at-home saliva test to evaluate each individual’s genetic profile and predict potential genetic risks for future children. In cases of elevated risk, Orchid provides actionable insights to assist couples in monitoring health markers, adjusting their diet, or considering procedures like in vitro fertilization.

General Galactic is a technology company that produces clean fuel by converting air and waste CO2 into synthetic hydrocarbons using renewable electricity. Its modular hardware systems enable on-site fuel production, making clean energy more accessible and affordable. The company's technology captures and upgrades emissions from various sources, transforming them into renewable hydrocarbon fuels that are compatible with existing infrastructure.

Hyfé is a feedstock processing company focused on transforming food waste into valuable chemicals and materials, thereby promoting sustainability in various industries. By utilizing fungal fermentation, Hyfé upcycles waste generated during food manufacturing, enabling the production of cost-competitive essential goods. This innovative approach not only maximizes profits for food manufacturers but also contributes to reducing the carbon footprint of the food industry. Through its commitment to creating sustainable chemicals, materials, fuels, and foods, Hyfé aims to unlock the full value of every crop while providing alternatives to petroleum-based products.

Modulo Bio simulates the neuroimmune system to find medication candidates that target microglia cells. The organization's proprietary neuroimmune platform combines the most recent developments in stem cell biology and neuroscience with software, automation, and artificial intelligence to create novel treatments.

Macro Oceans is a company focused on developing technology that harnesses the restorative power of seaweed to promote a cleaner, bio-based economy. It has created a multi-product zero-waste system aimed at restoring ocean vitality. The company specializes in a gentle extraction process that preserves the unique bioactive compounds found in seaweed, allowing it to produce a range of all-natural, functional plant-based ingredients. These ingredients are utilized in the development of bioplastics for packaging and other applications, enabling businesses to meet customer demands for environmentally friendly products that are carbon-neutral and fully traceable. Through its innovative approach, Macro Oceans contributes to sustainability and environmental stewardship while advancing the use of renewable resources.

Melonfrost is a biotechnology company located in Brooklyn, New York. It specializes in developing a clinical research platform aimed at optimizing biological strains by addressing operational bottlenecks. The company employs a combination of machine learning, proprietary artificial intelligence, and advanced hardware to facilitate real-time cell evolution. This innovative approach enables Melonfrost to explore the biological landscape effectively and implement advancements in robotics, sensing, fluidics, and environmental control. By streamlining scientific labor processes, Melonfrost significantly reduces the time required to bring bioproducts to market, thereby enhancing the efficiency and effectiveness of biotechnological innovations.

Parallel Bio is a biotechnology company focused on advancing the discovery and development of immunotherapies. The company's platform integrates best-in-class human immune organoids with computational methods to provide deep insights into human health and disease. This approach aims to overcome current barriers in immunotherapy research, accelerating the path to effective treatments. Parallel Bio's tools are designed to enhance the development of various therapies, including cell therapies, antibody therapies, and vaccines, offering medical professionals novel perspectives on human biology.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, founded in 2016. It focuses on producing industrial chemicals through the application of biotechnology and green chemistry, specifically utilizing plant-derived substitutes to replace petroleum-based products. The company offers a range of products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. Other offerings include ScavSol, a multivalent metal sequestrant for energy applications, ScaleSol, an alternative to phosphonates for scale control, and CorrSol, which addresses corrosion and fouling. Solugen's innovative approach combines fermentation and petrochemical processing along with advancements in synthetic biology and enzymatic technology, enabling it to create environmentally friendly chemicals from bio-based feedstocks. Its solutions cater to diverse industries such as agriculture, cleaning, energy, and water, contributing to reduced costs and lower carbon emissions while promoting sustainability.

YourChoice Therapeutics, Inc. is a biotechnology company based in Berkeley, California, founded in 2018. The company focuses on developing non-hormonal contraceptive products aimed at providing women with safe and effective birth control options. Its innovative technology is based on the concept of a "molecular condom," which utilizes an active compound to inhibit sperm motility, thereby preventing sperm from fertilizing the egg. This approach seeks to eliminate the risks and side effects commonly associated with traditional hormonal contraceptive methods, offering a promising alternative for those seeking safer birth control solutions.

FYTO, Inc. is a company based in Cambridge, Massachusetts, founded in 2019, that specializes in the development of plant-based feed production systems. The firm focuses on creating nutrient-dense crops and innovative cultivation and harvesting systems designed to enhance agricultural quality and consistency. FYTO's offerings include a variety of agricultural products such as animal feed, fodder, plant-based proteins, nutritional supplements, and bio-fertilizers. By employing climate-friendly methodologies, the company aims to improve both the economic and environmental sustainability of agriculture, providing personalized solutions to farmers worldwide that promote ultra-high yields while minimizing resource requirements.

Ness builds a credit card-first wedge into healthcare. It allows its user to earn rewards for healthy purchases and access exclusive perks to complement their lifestyle. It was established in 2021 and is based in New York, United States.

Evernow is a provider of women's health care services focused on the unique needs of women before, during, and after menopause. The company offers an online teleconsultation platform that connects users with specialized doctors and provides access to science-backed information and treatments. This platform facilitates discussions and delivers resources on effective care for hormonal changes, empowering women to manage their health and enhance their quality of life during this significant life stage.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

64x Bio is a biotechnology company that specializes in accelerating the discovery of mammalian cell lines for biomanufacturing and therapeutic applications. The company has developed a high-throughput discovery and screening platform that integrates advanced computational design techniques. This platform enables the creation of highly optimized cell lines specifically tailored for the production of viral vectors, which are crucial for cell and gene therapies. By providing purpose-built genetically engineered cell lines, 64x Bio aims to enhance the efficiency of viral vector production, helping pharmaceutical and biotechnology companies improve their manufacturing capabilities while reducing associated costs.

Phytoform Labs Ltd, established in 2017 and headquartered in London, specializes in agricultural biotechnology. The company offers genome editing services to crop breeders worldwide, aiming to accelerate plant breeding from decades to years. By leveraging new gene editing technologies and artificial intelligence, Phytoform helps breeders create diverse, sustainable crops with improved yields, ultimately enhancing the economics of breeding for customers.

Mythic Therapeutics is a biotechnology company dedicated to advancing cancer treatments through innovative therapies. The company specializes in the development of antibody-drug conjugates (ADCs), utilizing a unique protein engineering approach that enhances the effectiveness of these targeted therapies. Mythic Therapeutics' technology significantly improves the uptake of therapeutic agents in cancerous cells while minimizing their release in healthy cells, thereby increasing efficacy across various cancer types. This method not only boosts the potency of the treatments but also ensures a favorable safety profile, enabling healthcare providers to harness the full potential of ADCs. As such, Mythic Therapeutics aims to make a meaningful impact on cancer care by addressing a broad spectrum of tumor targets.

Ophelia Health, Inc., established in 2019 and headquartered in New York, specializes in medication-assisted treatment for opioid dependency. The company facilitates telemedicine consultations between patients and doctors, providing necessary medications at home. Ophelia differentiates itself by combining medical expertise with a client-centered approach, prioritizing privacy and empowering individuals to make their own treatment decisions.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, founded in 2016. It focuses on producing industrial chemicals through the application of biotechnology and green chemistry, specifically utilizing plant-derived substitutes to replace petroleum-based products. The company offers a range of products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. Other offerings include ScavSol, a multivalent metal sequestrant for energy applications, ScaleSol, an alternative to phosphonates for scale control, and CorrSol, which addresses corrosion and fouling. Solugen's innovative approach combines fermentation and petrochemical processing along with advancements in synthetic biology and enzymatic technology, enabling it to create environmentally friendly chemicals from bio-based feedstocks. Its solutions cater to diverse industries such as agriculture, cleaning, energy, and water, contributing to reduced costs and lower carbon emissions while promoting sustainability.

Knowde is a software platform designed for the chemical industry, facilitating digital transformation for global chemical producers and distributors. It operates an online marketplace that enhances the accessibility of trading chemicals, polymers, and industrial ingredients. Leveraging the world's largest, purpose-built chemical taxonomy, Knowde employs advanced technologies, including deep learning, to enable users to efficiently search, filter, sample, quote, and purchase products tailored to their needs. This innovative approach allows clients to compare offerings from various suppliers, streamlining procurement processes and unlocking new opportunities within chemical operations.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Ophelia Health, Inc., established in 2019 and headquartered in New York, specializes in medication-assisted treatment for opioid dependency. The company facilitates telemedicine consultations between patients and doctors, providing necessary medications at home. Ophelia differentiates itself by combining medical expertise with a client-centered approach, prioritizing privacy and empowering individuals to make their own treatment decisions.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Astranis is a company focused on developing innovative satellite technology designed to deliver data to specific locations on Earth with each satellite it launches. The primary mission of Astranis is to provide high-speed, reliable internet access to underserved regions at a significantly lower cost compared to traditional methods. By doing so, the company aims to bridge the digital divide and connect the approximately 4 billion people worldwide who currently lack internet access, thereby supporting governments and businesses in their efforts to expand global connectivity.

Orchid is a reproductive technology startup founded in 2019 and headquartered in San Francisco, California. The company specializes in detecting rare genetic disorders through its preconception system, which analyzes the genomes of both partners to assess their genetic predispositions to various common diseases, such as heart disease, Alzheimer’s disease, and breast cancer. Orchid develops its results in collaboration with leading experts in reproductive medicine and genetics, ensuring high accuracy. The company offers a "Couple Report," which utilizes an at-home saliva test to evaluate each individual’s genetic profile and predict potential genetic risks for future children. In cases of elevated risk, Orchid provides actionable insights to assist couples in monitoring health markers, adjusting their diet, or considering procedures like in vitro fertilization.

Spora Health, Inc. is a telemedicine provider based in San Francisco, California, focused on delivering primary care specifically designed for people of color. Established in 2019, the company employs machine learning-driven technology to assess risk profiles and identify chronic conditions such as pre-diabetes, hypertension, and emphysema. Spora Health offers a range of treatments addressing various health issues, including allergies, infections, digestive system disorders, musculoskeletal problems, reproductive health, and skin conditions. The platform facilitates communication between patients and a diverse care team, which includes doctors, nurse practitioners, and nutritionists, enabling individuals to receive tailored healthcare advice and support in navigating their health journeys effectively.

Brave Care, Inc. specializes in urgent pediatric health care services, providing treatment for a wide range of conditions such as allergies, asthma, cough, ear pain, eye problems, fever, minor fractures, and more. The company also offers pediatric-specific laboratory services and on-site x-ray facilities. Founded in 2019 and headquartered in Portland, Oregon, Brave Care operates primary and urgent care clinics designed exclusively for children in Oregon and Texas. In addition to in-person care, Brave Care provides pediatric advice to parents through its website and mobile app, supporting families nationwide in promoting their children's well-being.

Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing innovative therapies that target senescent cells implicated in age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of therapeutic candidates. These candidates are designed to selectively address senescent cells, as well as pro-inflammatory and pro-fibrotic cell populations that contribute to various chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises industry experts with significant experience in drug development and commercialization across both large pharmaceutical companies and biotech firms.

64x Bio is a biotechnology company that specializes in accelerating the discovery of mammalian cell lines for biomanufacturing and therapeutic applications. The company has developed a high-throughput discovery and screening platform that integrates advanced computational design techniques. This platform enables the creation of highly optimized cell lines specifically tailored for the production of viral vectors, which are crucial for cell and gene therapies. By providing purpose-built genetically engineered cell lines, 64x Bio aims to enhance the efficiency of viral vector production, helping pharmaceutical and biotechnology companies improve their manufacturing capabilities while reducing associated costs.

Curative is a healthcare services company founded in 2020 that specializes in providing employer-based health insurance plans with a focus on affordability, engagement, and simplicity. The company aims to make essential healthcare more accessible by offering plans with competitive monthly premiums and no additional costs such as copays or deductibles. Curative's service offerings include COVID-19 testing through self-administered oral fluid swabs, vaccinations, baseline visits, virtual urgent care, and other health services designed to facilitate trusted relationships with providers and care navigators.

ANA Therapeutics Inc. is a biotechnology company focused on developing innovative therapeutic solutions for the treatment of coronavirus, specifically COVID-19. Founded in 2020 and based in Foster City, California, the company is advancing a proprietary formulation of niclosamide, marketed under the name ANA001. This drug is delivered in capsule form and is currently undergoing human clinical trials. The objective of ANA Therapeutics is to provide effective treatment options for medical practitioners to help patients affected by the coronavirus pandemic, thereby aiming to contribute to the global response to this public health crisis.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Magic is a technology company that specializes in password-less authentication solutions, providing an alternative login method that enhances security and user experience. Its innovative technology employs a plug-and-play kit combined with blockchain infrastructure, enabling developers to easily integrate customizable password-less login features into their applications. With just a few lines of code, developers can implement this scalable solution, allowing users to access services without traditional passwords, thus streamlining the login process and reducing security risks associated with password management.

Ophelia Health, Inc., established in 2019 and headquartered in New York, specializes in medication-assisted treatment for opioid dependency. The company facilitates telemedicine consultations between patients and doctors, providing necessary medications at home. Ophelia differentiates itself by combining medical expertise with a client-centered approach, prioritizing privacy and empowering individuals to make their own treatment decisions.

Knowde is a software platform designed for the chemical industry, facilitating digital transformation for global chemical producers and distributors. It operates an online marketplace that enhances the accessibility of trading chemicals, polymers, and industrial ingredients. Leveraging the world's largest, purpose-built chemical taxonomy, Knowde employs advanced technologies, including deep learning, to enable users to efficiently search, filter, sample, quote, and purchase products tailored to their needs. This innovative approach allows clients to compare offerings from various suppliers, streamlining procurement processes and unlocking new opportunities within chemical operations.

Red Leader Technologies is a hardware and software company established in 2018 and headquartered in Palo Alto, California. The company specializes in developing advanced HD software-defined lidar systems designed for 3D mapping applications. These systems function as high-resolution three-dimensional cameras, offering full-depth information. Red Leader's technology features controllable zoom-in capabilities without relying on beam steering hacks, allowing for the simultaneous imaging of hundreds of lasers rather than just one. This innovation enhances image resolution and improves manufacturability, facilitating easy integration for clients across various industries.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, founded in 2016. It focuses on producing industrial chemicals through the application of biotechnology and green chemistry, specifically utilizing plant-derived substitutes to replace petroleum-based products. The company offers a range of products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. Other offerings include ScavSol, a multivalent metal sequestrant for energy applications, ScaleSol, an alternative to phosphonates for scale control, and CorrSol, which addresses corrosion and fouling. Solugen's innovative approach combines fermentation and petrochemical processing along with advancements in synthetic biology and enzymatic technology, enabling it to create environmentally friendly chemicals from bio-based feedstocks. Its solutions cater to diverse industries such as agriculture, cleaning, energy, and water, contributing to reduced costs and lower carbon emissions while promoting sustainability.

Avail Medsystems, Inc. is a digital healthcare company based in Palo Alto, California, that specializes in developing a comprehensive hardware and software platform designed to connect healthcare professionals remotely. The company offers a fully integrated audio/visual system that facilitates real-time collaboration and procedural support, enabling practitioners to access clinical expertise and education without the constraints of physical location. By democratizing access to specialized knowledge and services, Avail Medsystems enhances the efficiency of healthcare delivery and promotes the adoption of innovative medical technologies. Founded in 2012 and previously known as Nurep, Inc., the company aims to improve patient care by bridging gaps between healthcare providers and medical technology experts.

Astranis is a company focused on developing innovative satellite technology designed to deliver data to specific locations on Earth with each satellite it launches. The primary mission of Astranis is to provide high-speed, reliable internet access to underserved regions at a significantly lower cost compared to traditional methods. By doing so, the company aims to bridge the digital divide and connect the approximately 4 billion people worldwide who currently lack internet access, thereby supporting governments and businesses in their efforts to expand global connectivity.

Uniform Teeth is an orthodontics practice focused on delivering accessible and high-quality orthodontic care. The company operates dental clinics that utilize a modern approach to treatment, specializing in clear teeth aligners. These aligners are crafted from biocompatible, BPA-free plastic designed to fit snugly over the teeth at each stage of the orthodontic process. By prioritizing patient experience and innovative technology, Uniform Teeth aims to simplify the journey to achieving straightened teeth.

Redesign Science, established in 2017 and based in New York, is a biotechnology company specializing in small molecule drug discovery. It employs a computational chemistry platform to accelerate drug development by simulating protein targets at the atomic level, revealing subtle drug opportunities that traditional methods may miss. The company aims to set a new standard in early-stage drug discovery, leveraging first-principles physics and artificial intelligence to create generative AI for drug discovery, with a focus on high unmet medical needs.

Tempest, Inc. is a digital recovery program that provides online courses and resources for individuals seeking to quit alcohol. Founded in 2014 and based in New York, the company offers a comprehensive virtual curriculum that includes an eight-week course, counseling sessions, and workshops designed to address the challenges of alcohol addiction. Tempest emphasizes the development of purpose, meaning, and creativity as essential components of a sober lifestyle. The program aims to support participants in overcoming negativity and mental health challenges associated with substance use, ultimately helping them lead healthier and more fulfilling lives. Originally established as Hip Sobriety, Inc., the company rebranded to Tempest, Inc. in May 2019.

Brave Care, Inc. specializes in urgent pediatric health care services, providing treatment for a wide range of conditions such as allergies, asthma, cough, ear pain, eye problems, fever, minor fractures, and more. The company also offers pediatric-specific laboratory services and on-site x-ray facilities. Founded in 2019 and headquartered in Portland, Oregon, Brave Care operates primary and urgent care clinics designed exclusively for children in Oregon and Texas. In addition to in-person care, Brave Care provides pediatric advice to parents through its website and mobile app, supporting families nationwide in promoting their children's well-being.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Umbrella, Inc. is a service-oriented company based in Brooklyn, New York, founded in 1995. It specializes in providing home maintenance services through a membership model, focusing on assisting senior citizens with everyday chores and repairs. The company's platform connects users with local workers for a variety of tasks, including home repair and maintenance, plumbing, A/C installation, small electrical updates, carpentry, and seasonal tasks such as spring cleaning and garage or basement cleanup. By facilitating these services, Umbrella enables seniors to maintain their independence and comfort while living in their own homes.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, founded in 2016. It focuses on producing industrial chemicals through the application of biotechnology and green chemistry, specifically utilizing plant-derived substitutes to replace petroleum-based products. The company offers a range of products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. Other offerings include ScavSol, a multivalent metal sequestrant for energy applications, ScaleSol, an alternative to phosphonates for scale control, and CorrSol, which addresses corrosion and fouling. Solugen's innovative approach combines fermentation and petrochemical processing along with advancements in synthetic biology and enzymatic technology, enabling it to create environmentally friendly chemicals from bio-based feedstocks. Its solutions cater to diverse industries such as agriculture, cleaning, energy, and water, contributing to reduced costs and lower carbon emissions while promoting sustainability.

Kin Euphorics is a New York-based company founded in 2017 that specializes in non-alcoholic beverages designed for adults. The company offers ready-to-drink social tonics made from a blend of nootropics, adaptogens, and botanicals. These functional beverages aim to provide a unique experience reminiscent of craft cocktails, promoting focused relaxation by calming synaptic signaling in the brain while avoiding drowsiness. Kin Euphorics seeks to enable customers to unwind and nourish their minds while enjoying social interactions without the effects of alcohol.

Vital is a health insurance company that offers innovative financial solutions, including medical credit lines and loans, to help patients manage their healthcare expenses. Additionally, Vital employs AI-powered technology to enhance patient experience, providing real-time information and support throughout their healthcare journey, from emergency room visits to post-discharge care.

Culture Biosciences, Inc. is a biotechnology company based in South San Francisco, California, that offers an innovative biomanufacturing platform designed for scientists to efficiently run, monitor, and analyze bioreactor experiments through the cloud. Founded in 2016, the company specializes in developing automated bioreactors and fermentation tools that enable biotech companies to optimize their manufacturing processes. By leveraging robotic sample handling and cloud-based data monitoring and analysis, Culture Biosciences significantly accelerates the ability of scientists to manage bioreactor operations compared to traditional methods. This allows for faster product development and market readiness, streamlining the biomanufacturing workflow for its clients.

AKASA is a leading developer of AI-powered automation solutions specifically designed for the healthcare revenue cycle. The company focuses on streamlining complex workflows, enabling healthcare providers to enhance revenue outcomes and operational efficiency. By applying advanced technologies such as artificial intelligence, AKASA automates time-consuming revenue cycle tasks, including prior authorization and claims processing, which were previously challenging to resolve at scale. This innovative approach helps healthcare institutions reduce accounts receivable days, increase efficiency, and save significant staff time, ultimately improving financial performance. AKASA's solutions are grounded in deep revenue cycle expertise and uphold high standards of data security, delivering reliable results with accuracy and speed. The company has raised over $200 million from notable investors to further its mission of simplifying the financial complexities in healthcare.

Cambridge Cancer Genomics Limited is a biotechnology company based in Cambridge, United Kingdom, focused on developing innovative diagnostic tests for cancer patients. Founded in 2016, the company leverages liquid biopsy techniques, artificial intelligence, and genomics to create personalized tests that monitor treatment responses in real-time. By analyzing circulating tumor DNA from simple blood draws, Cambridge Cancer Genomics enables clinicians to detect cancer relapses earlier than conventional methods, predict patient responses to therapies, and adjust treatment regimens promptly to enhance patient outcomes. The company collaborates with cancer clinics, academic institutions, biotech startups, and pharmaceutical firms to transform cancer care and improve the overall quality of life and survival rates for patients.

Knowde is a software platform designed for the chemical industry, facilitating digital transformation for global chemical producers and distributors. It operates an online marketplace that enhances the accessibility of trading chemicals, polymers, and industrial ingredients. Leveraging the world's largest, purpose-built chemical taxonomy, Knowde employs advanced technologies, including deep learning, to enable users to efficiently search, filter, sample, quote, and purchase products tailored to their needs. This innovative approach allows clients to compare offerings from various suppliers, streamlining procurement processes and unlocking new opportunities within chemical operations.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, founded in 2016. It focuses on producing industrial chemicals through the application of biotechnology and green chemistry, specifically utilizing plant-derived substitutes to replace petroleum-based products. The company offers a range of products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. Other offerings include ScavSol, a multivalent metal sequestrant for energy applications, ScaleSol, an alternative to phosphonates for scale control, and CorrSol, which addresses corrosion and fouling. Solugen's innovative approach combines fermentation and petrochemical processing along with advancements in synthetic biology and enzymatic technology, enabling it to create environmentally friendly chemicals from bio-based feedstocks. Its solutions cater to diverse industries such as agriculture, cleaning, energy, and water, contributing to reduced costs and lower carbon emissions while promoting sustainability.

Hero is an innovative company focused on transforming medication management for patients and caregivers. It has developed the first in-home medication manager that efficiently sorts and dispenses medications while providing audible and digital reminders. The platform automates prescription refills and offers real-time and historical adherence data, making it easier for users to track their medication usage. By leveraging digital technologies, Hero enhances patient engagement and monitors non-physiologic health data, particularly for those with chronic diseases. The company's mission is to create user-friendly solutions that address significant challenges in healthcare, ultimately improving patient outcomes through better medication adherence.

Blockfolio, Inc. is a company that specializes in developing a mobile application for cryptocurrency portfolio tracking and management. Founded in 2014 and based in Marina Del Rey, California, Blockfolio's application enables users to build and monitor their cryptocurrency portfolios, providing real-time prices, market data, and news updates from prominent figures in the crypto sector. The platform also facilitates automated portfolio tracking by integrating with users' exchange accounts, allowing for seamless management of investments. With millions of users, Blockfolio is recognized for its commitment to providing free access and valuable insights, helping individuals stay informed about the dynamic cryptocurrency landscape. As of August 2020, Blockfolio operates as a subsidiary of FTX Trading LTD.

FactoryFour is a software company founded in 2015 and based in Baltimore, Maryland, that specializes in developing solutions to manage and automate manufacturing processes. Its cloud-based manufacturing execution system (MES) is designed to enhance productivity, predictability, and profitability in digital fabrication. The software offers real-time manufacturing data that supports business decisions, facilitates production planning, and automates scheduling through customizable logic tailored to specific operations. By providing a modern, user-friendly technology stack, FactoryFour aims to eliminate the drawbacks of traditional manufacturing systems, such as inflexibility and high costs, allowing clients to configure, capture, and analyze their operations efficiently.

Checkerspot, Inc. is a biotechnology company based in Berkeley, California, founded in 2016. It specializes in the development of sustainable performance materials derived from microalgae and biobased oils. The company focuses on innovating materials at a molecular level, utilizing its expertise in molecular foundry, chemistry, material science, and fabrication technology. Checkerspot aims to expand the range of molecular building blocks available for high-performance materials, particularly in industrial applications such as polyurethanes and textile finishes. Through its pioneering approach, Checkerspot contributes to the advancement of sustainable materials in various industries.

Shield Bio is a biotechnology company focused on combating antibiotic resistance, a growing public health crisis projected to surpass cancer-related deaths by 2050. The company has developed a novel genomic testing platform that enables sexually transmitted infection (STI) clinics to accurately identify antibiotic-resistant strains of pathogens, particularly gonorrhea, which has shown resistance to multiple antibiotics. With approximately 820,000 new gonorrhea infections annually in the United States and the Centers for Disease Control and Prevention designating resistant strains as an urgent threat, Shield Bio's rapid and precise molecular antibiotic susceptibility testing is critical. This platform allows healthcare providers to determine the most effective antibiotics for treatment, thereby enhancing patient outcomes and helping to curb the spread of antibiotic resistance.

Biobot Analytics, Inc. is a wastewater epidemiology company based in Cambridge, Massachusetts, founded in 2017. It specializes in transforming wastewater infrastructure into public health observatories through innovative technology that analyzes sewage for health-related data. By deploying proprietary sampling devices and spatial analytics, Biobot measures various health threats, including infectious diseases, antibiotic resistance, and drug consumption patterns. The company's Opioid Consumption Monitoring Program specifically estimates opioid use in urban areas by analyzing wastewater. This approach generates anonymized public health data that is independent of traditional hospital reporting systems, allowing for rapid adaptability to emerging public health threats. Biobot Analytics offers its insights as a service, providing government officials with actionable data to prioritize interventions and address public health challenges effectively.

Astranis is a company focused on developing innovative satellite technology designed to deliver data to specific locations on Earth with each satellite it launches. The primary mission of Astranis is to provide high-speed, reliable internet access to underserved regions at a significantly lower cost compared to traditional methods. By doing so, the company aims to bridge the digital divide and connect the approximately 4 billion people worldwide who currently lack internet access, thereby supporting governments and businesses in their efforts to expand global connectivity.

BioRender is a Canadian company founded in 2017 that specializes in scientific visualization tools designed for the pharmaceutical and life sciences sectors. Its platform enables scientists to create and share professional-grade scientific figures with ease, utilizing a library of intuitive icons that adhere to standard visual language in science. This allows for accurate and accessible communication of complex concepts. The cloud-based service supports users in quickly composing custom images without the need for drawing skills, facilitating the efficient presentation of research findings. BioRender's approach not only saves time and costs but also enhances the ability of researchers to disseminate their work effectively.

Uniform Teeth is an orthodontics practice focused on delivering accessible and high-quality orthodontic care. The company operates dental clinics that utilize a modern approach to treatment, specializing in clear teeth aligners. These aligners are crafted from biocompatible, BPA-free plastic designed to fit snugly over the teeth at each stage of the orthodontic process. By prioritizing patient experience and innovative technology, Uniform Teeth aims to simplify the journey to achieving straightened teeth.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, founded in 2016. It focuses on producing industrial chemicals through the application of biotechnology and green chemistry, specifically utilizing plant-derived substitutes to replace petroleum-based products. The company offers a range of products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. Other offerings include ScavSol, a multivalent metal sequestrant for energy applications, ScaleSol, an alternative to phosphonates for scale control, and CorrSol, which addresses corrosion and fouling. Solugen's innovative approach combines fermentation and petrochemical processing along with advancements in synthetic biology and enzymatic technology, enabling it to create environmentally friendly chemicals from bio-based feedstocks. Its solutions cater to diverse industries such as agriculture, cleaning, energy, and water, contributing to reduced costs and lower carbon emissions while promoting sustainability.

Octant Bio is a company focused on developing synthetic technology to enhance health and treat diseases. The firm employs synthetic biology, genome engineering, next-generation sequencing, and computational tools to measure the activity of thousands of receptor pathways in human cells simultaneously. This approach allows scientists to use machine learning methods to engineer small molecules that can interact with multiple receptors, offering new potential for treating complex diseases.

Enzyme is a software developer focused on assisting life sciences companies with FDA approval and regulatory compliance. Their cloud-based platform automates and simplifies compliance workflows, ensuring that businesses in medical device, diagnostic, and drug development sectors meet FDA standards efficiently. By utilizing Enzyme's technology, companies can significantly reduce compliance costs—potentially by up to 50 percent—while also minimizing the need for costly consultants. This efficiency can lead to a reduction in personnel dedicated to regulatory issues, as approximately 10 percent of staff in biopharma and life sciences are involved in compliance. Ultimately, Enzyme's platform aims to streamline the process, enabling faster and easier market entry for life sciences innovations.

Knowde is a software platform designed for the chemical industry, facilitating digital transformation for global chemical producers and distributors. It operates an online marketplace that enhances the accessibility of trading chemicals, polymers, and industrial ingredients. Leveraging the world's largest, purpose-built chemical taxonomy, Knowde employs advanced technologies, including deep learning, to enable users to efficiently search, filter, sample, quote, and purchase products tailored to their needs. This innovative approach allows clients to compare offerings from various suppliers, streamlining procurement processes and unlocking new opportunities within chemical operations.

Cofactor Genomics is a biotechnology company that specializes in predictive immune modeling and RNA sequencing. By advancing precision medicine, Cofactor aims to address existing barriers in the healthcare sector, transitioning from single-analyte biomarkers to comprehensive multidimensional biomarkers through health expression models. The company operates one of the first CAP-certified clinical RNA sequencing laboratories, which enhances the efficiency and cost-effectiveness of clinical trials for their partners. Cofactor’s expertise encompasses molecular biology, informatics, and database management, allowing them to provide high-quality services tailored to the needs of the healthcare and pharmaceutical industries. Their focus on RNA biomarkers associated with responses to targeted therapeutics supports the commercialization of clinical diagnostic assays for oncologic, immunologic, and neurodegenerative diseases, ultimately contributing to medical research and improved patient outcomes.

Call9, Inc. is a healthcare technology company based in Brooklyn, New York, that offers a mobile platform designed for nursing home patients to access emergency medical care. Since its incorporation in 2015, Call9 has developed a tele-EM platform that enables skilled nursing facility nurses to quickly connect with on-site Clinical Care Specialists and Board Certified Emergency Medicine Physicians during acute medical events. This innovative approach allows for expedited treatment and point-of-care diagnostics, significantly improving patient outcomes. By providing immediate care at the bedside, Call9 helps to keep over 80% of patients in their nursing home, thereby reducing unnecessary hospital transfers and saving substantial healthcare costs. The company's services are tailored to organizations with trained medical personnel, enhancing their ability to respond effectively to emergencies.

Gencove is a software platform that specializes in high-throughput, cost-effective genome sequencing, utilizing low-pass sequencing technology. The company focuses on developing molecular and computational tools aimed at making whole-genome sequencing fast, affordable, and actionable. By setting a new standard in genomics research and diagnostics, Gencove caters to a wide range of industries, including agriculture and pharmaceuticals, thereby providing researchers with accessible genomic data.

Clover Health Inc. is a health insurance company that specializes in providing Medicare Advantage plans primarily for senior citizens. Founded in 2014 and headquartered in San Francisco, California, the company operates in several states, including New Jersey, Arizona, Georgia, Pennsylvania, South Carolina, Tennessee, and Texas. Clover Health utilizes a Preferred Provider Organization (PPO) platform to enhance the quality of life for its members and their healthcare providers. The company employs patient-centered analytics and a dedicated care management team to identify potential health risks and deliver preventive care, thereby aiming to minimize avoidable spending and manage chronic diseases. Its proprietary software platform, Clover Assistant, offers personalized insights to physicians, supporting early detection and effective management of chronic conditions. Clover Health generates the majority of its revenue from its insurance segment, which includes both PPO and HMO plans.

Plutoshift is an operational data platform based in Palo Alto, California, founded in 2017. The company focuses on empowering operators to automate performance monitoring across various industrial workflows. By leveraging existing data collection systems, Plutoshift automates data workflows and delivers a unified view of performance. Its platform enables businesses to enhance return on investment by minimizing resource consumption and operating costs. Additionally, Plutoshift facilitates data-driven operations by providing actionable insights and AI capabilities directly to front-line operators, managers, and executives. This approach allows for automatic monitoring of critical processes, ultimately improving operational efficiency and decision-making.

TL Biolabs Corp., established in 2016 and headquartered in Santa Clara, California, specializes in providing automated genomic testing services for the livestock industry, focusing on beef and dairy cattle. The company offers affordable genomic tests along with complimentary software to deliver practical insights from test results.

Shield Bio is a biotechnology company focused on combating antibiotic resistance, a growing public health crisis projected to surpass cancer-related deaths by 2050. The company has developed a novel genomic testing platform that enables sexually transmitted infection (STI) clinics to accurately identify antibiotic-resistant strains of pathogens, particularly gonorrhea, which has shown resistance to multiple antibiotics. With approximately 820,000 new gonorrhea infections annually in the United States and the Centers for Disease Control and Prevention designating resistant strains as an urgent threat, Shield Bio's rapid and precise molecular antibiotic susceptibility testing is critical. This platform allows healthcare providers to determine the most effective antibiotics for treatment, thereby enhancing patient outcomes and helping to curb the spread of antibiotic resistance.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Legalist, Inc. is a San Francisco-based company that specializes in data-driven litigation financing services. Founded in 2016 and incubated at Y Combinator, Legalist employs proprietary sourcing technology to identify and underwrite litigation investments on a non-recourse basis. This approach allows plaintiffs and their attorneys to manage legal expenses effectively while mitigating risk associated with litigation. By focusing on generating risk-adjusted returns, Legalist aims to streamline the legal process for its clients, offering them the necessary financial support to navigate complex legal challenges.

Finova Financial LLC, founded in 2015 and based in Palm Beach Gardens, Florida, operates a digital financial services platform focused on providing accessible loans to financially underserved Americans. By leveraging the equity in vehicles, Finova offers a Car Equity Line of Credit (C-LOC) that significantly reduces costs compared to traditional lending options. The C-LOC facilitates fast, affordable loans with instant approval and same-day cash funding. Clients benefit from a user-friendly online portal that allows for real-time management of financial health, with the ability to make payments conveniently through computers or mobile devices. Finova's approach aims to build positive relationships with clients, offering not only credit solutions but also ongoing financial education to support economic improvement. Through this innovative platform, Finova seeks to address the financial needs of millions while fostering financial responsibility and growth.

Trace Genomics, Inc. is a company focused on advancing soil health and microbiome analysis through artificial intelligence-based diagnostic tools designed for farmers. The company provides a soil microbiome test that utilizes DNA sequencing and a comprehensive database of microbial species to predict soil diseases, assess soil health, and enhance crop quality. By analyzing the microbial composition and diversity within soil samples, Trace Genomics offers valuable insights that empower farmers to make informed decisions regarding soil management, crop selection, and the application of fertilizers. Founded in 2015 and headquartered in Burlingame, California, with an additional office in Ames, Iowa, Trace Genomics aims to support sustainable agricultural practices by providing actionable information that enhances soil productivity and sustainability.

Astranis is a company focused on developing innovative satellite technology designed to deliver data to specific locations on Earth with each satellite it launches. The primary mission of Astranis is to provide high-speed, reliable internet access to underserved regions at a significantly lower cost compared to traditional methods. By doing so, the company aims to bridge the digital divide and connect the approximately 4 billion people worldwide who currently lack internet access, thereby supporting governments and businesses in their efforts to expand global connectivity.

Clover Health Inc. is a health insurance company that specializes in providing Medicare Advantage plans primarily for senior citizens. Founded in 2014 and headquartered in San Francisco, California, the company operates in several states, including New Jersey, Arizona, Georgia, Pennsylvania, South Carolina, Tennessee, and Texas. Clover Health utilizes a Preferred Provider Organization (PPO) platform to enhance the quality of life for its members and their healthcare providers. The company employs patient-centered analytics and a dedicated care management team to identify potential health risks and deliver preventive care, thereby aiming to minimize avoidable spending and manage chronic diseases. Its proprietary software platform, Clover Assistant, offers personalized insights to physicians, supporting early detection and effective management of chronic conditions. Clover Health generates the majority of its revenue from its insurance segment, which includes both PPO and HMO plans.

Alloy.ai is a demand and inventory control tower designed specifically for consumer goods brands, aimed at enhancing product sales and streamlining complex supply chain challenges. The platform delivers daily insights at the SKU-store level, allowing brands to swiftly identify and respond to issues, often in seconds rather than days. Built on a cloud data platform, Alloy.ai integrates over 850 pre-built connectors to combine point-of-sale and inventory data with supply chain information, offering comprehensive visibility into demand and inventory across the entire network. This capability enables companies to reduce out-of-stock situations by over 35% and positively impact their bottom line by more than 5%, resulting in significant incremental orders from retail partners. Alloy.ai serves a diverse clientele, including both Fortune 500 companies and digital-native brands, such as Ferrero, Bic, Valvoline, Bosch, and Melissa & Doug.

Finova Financial LLC, founded in 2015 and based in Palm Beach Gardens, Florida, operates a digital financial services platform focused on providing accessible loans to financially underserved Americans. By leveraging the equity in vehicles, Finova offers a Car Equity Line of Credit (C-LOC) that significantly reduces costs compared to traditional lending options. The C-LOC facilitates fast, affordable loans with instant approval and same-day cash funding. Clients benefit from a user-friendly online portal that allows for real-time management of financial health, with the ability to make payments conveniently through computers or mobile devices. Finova's approach aims to build positive relationships with clients, offering not only credit solutions but also ongoing financial education to support economic improvement. Through this innovative platform, Finova seeks to address the financial needs of millions while fostering financial responsibility and growth.

Call9, Inc. is a healthcare technology company based in Brooklyn, New York, that offers a mobile platform designed for nursing home patients to access emergency medical care. Since its incorporation in 2015, Call9 has developed a tele-EM platform that enables skilled nursing facility nurses to quickly connect with on-site Clinical Care Specialists and Board Certified Emergency Medicine Physicians during acute medical events. This innovative approach allows for expedited treatment and point-of-care diagnostics, significantly improving patient outcomes. By providing immediate care at the bedside, Call9 helps to keep over 80% of patients in their nursing home, thereby reducing unnecessary hospital transfers and saving substantial healthcare costs. The company's services are tailored to organizations with trained medical personnel, enhancing their ability to respond effectively to emergencies.

Verge Genomics is a biotechnology company focused on transforming drug discovery through the application of artificial intelligence. Founded by experts in machine learning and seasoned neuroscience drug developers, the company aims to leverage advancements in computational genomics and insights into neuroscience to discover innovative therapeutics for neurodegenerative diseases. Its drug discovery platform employs machine learning algorithms to analyze large datasets, identifying potential drug targets and predicting effective treatments. By accelerating the development of life-saving therapies, Verge Genomics seeks to enhance patient outcomes and reduce the costs associated with pharmaceutical development, thereby addressing critical challenges in the healthcare sector.

Headspace is a company dedicated to enhancing mental healthcare through its digital platform, which focuses on meditation, mindfulness, and overall mental well-being. The Headspace app features a diverse array of guided meditations led by experts, including its co-founder Andy Puddicombe, aimed at helping users reduce stress, improve focus, and cultivate mindfulness. It also offers specialized tools for sleep, such as "Sleepcasts," soundscapes, and guided sleep meditations, to aid users in achieving better rest. In addition to these features, Headspace provides mindfulness programs that address various aspects of daily life, including work, relationships, and health, while also focusing on managing mental health challenges like anxiety and depression. Furthermore, the company collaborates with organizations through corporate wellness programs, supplying resources designed to enhance employee productivity and well-being.

PicnicHealth is a company focused on simplifying access to medical records and utilizing data to advance medical research. It provides patients with a secure online dashboard that consolidates their medical records from various healthcare providers across the United States. This innovative platform allows individuals to manage their health information efficiently while also giving them the option to contribute their anonymized data for scientific research. By doing so, PicnicHealth enables life sciences researchers to gain insights into real-world disease management and treatment practices, enhancing the understanding of patient experiences beyond traditional clinical trials. The company has successfully assisted tens of thousands of patients and established partnerships with major biopharmaceutical firms, positioning itself as a key player in the evolving healthcare landscape.