Ocuphire Pharma

Ocuphire Pharma is a clinical-stage biopharmaceutical company based in Farmington Hills, Michigan, that specializes in developing and commercializing therapies for various ophthalmic disorders. The company’s lead product candidate is Nyxol, a once-daily preservative-free eye drop formulation designed to treat conditions such as dim light vision disturbances, pharmacologically-induced mydriasis, and presbyopia. Nyxol is currently in late-stage clinical development, supported by extensive safety and efficacy data from previous trials. Additionally, Ocuphire is advancing APX3330, an oral tablet aimed at addressing diabetic retinopathy and diabetic macular edema, which is in Phase 2 clinical development. The company is also exploring opportunities to acquire further ophthalmic assets and seeks strategic partnerships for global commercialization of its products.

Joe Schachle

COO

Mina Patel Sooch

Co-Founder and CEO

2 past transactions

Opus Genetics

Acquisition in 2024
Opus Genetics is a gene therapy company focused on addressing challenges related to the manufacturing of treatments for ultra-rare retinal degenerative diseases. By utilizing adeno-associated virus-based gene therapies, Opus aims to provide effective solutions for individuals suffering from blinding conditions. The company's patient-first approach emphasizes the importance of accessibility to these specialized treatments, ensuring that advancements in gene therapy reach those in need efficiently.

Rexahn Pharmaceuticals

Acquisition in 2020
Rexahn Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for cancer and other medical needs. The company's primary offerings include RX-3117, which is undergoing Phase IIa clinical trials for relapsed or refractory metastatic pancreatic cancer, as well as bladder, colon, lung, and cervical cancers. Other clinical-stage candidates include Archexin, an inhibitor of the protein kinase Akt, and Supinoxin (RX-5902), which targets various forms of cancer. In addition, the company is developing RX-0301 for hepatocellular carcinoma and has a robust preclinical pipeline featuring multiple anticancer drug candidates. Rexahn collaborates with various organizations, including academic institutions and biotechnology firms, to advance its research and development initiatives. Headquartered in Rockville, Maryland, the company aims to enhance patient outcomes by creating next-generation therapies that aim to improve efficacy while reducing the side effects commonly associated with cancer treatments.
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