Equalum Ltd. is a company that specializes in real-time data ingestion and processing, primarily targeting enterprises dealing with Big Data. Founded in June 2015 and headquartered in Tel Aviv, Israel, Equalum has developed a unique Data Beaming platform that enables the instantaneous transfer of operational data from diverse sources, such as message queues, sensors, files, applications, and databases, to various analytics environments and cloud services. The platform is designed for scalability and user-friendliness, leveraging the capabilities of Spark within an enterprise-grade framework. This innovation helps organizations enhance their data processing efficiency, surpassing traditional ETL methods and open-source solutions.
Xage Security, Inc. is a technology company that specializes in providing a blockchain-protected security platform specifically designed for industrial Internet of Things (IoT) applications. Founded in 2016 and based in Palo Alto, California, the company offers a range of products including the Xage Gateway, which connects to various IIoT edge devices, and the Xage Broker, which synchronizes credentials and policies between edge devices and central systems. Additional offerings include the Xage Client Agent for direct participation in the blockchain, the Xage Security Cloud for management and monitoring, and various management tools. Xage Security focuses on solutions such as tamper-proofing, edge authentication, role-based access control, and device lifecycle management. Its services cater to multiple industries, including energy, transportation, utilities, manufacturing, healthcare, and logistics, aiming to enhance data security and access control while mitigating advanced threats and ensuring a zero-trust security model.
Minerva Networks is a provider of carrier-grade IPTV service management software. Minerva offers an open platform and a set of applications that allows telcos to deliver TV services over their managed IP network.
Direct Flow Medical is a medical device company specializing in the development of transcatheter aortic tissue valve prostheses aimed at treating cardiac valve insufficiency. With approximately 1.2 million individuals over the age of 65 affected by calcified aortic valves, the company addresses a significant healthcare need, as only about 150,000 of these cases receive surgical treatment annually. The company's innovative technologies focus on improving patient outcomes and minimizing complications associated with heart valve replacement. By offering repeated assessments of hemodynamic performance prior to final implantation, Direct Flow Medical enables heart surgeons to perform valve replacements through less invasive procedures, thereby enhancing the safety and effectiveness of cardiac interventions.
Actelis Networks is the leading provider of high performance, scalable broadband over copper solutions to Telco, Mobile, and IoT networks. Actelis turns copper into a strategic asset that enables delivering reliable, high-speed Ethernet services and broadband access to more places and devices more quickly, easily, and cost-effectively than can be done by using fiber optics or microwave.
The company was founded in 1998 and headquartered in Fremont, California.
InnFocus is a biomaterials company, develops and provides products in ophthalmology. The company's product portfolio includes an intraocular lens for microincision surgery and an implantable device for glaucoma. The company was incorporated in 2003 and is based in Miami, Florida.
eBags, Inc. is a prominent online retailer specializing in a diverse range of bags and travel accessories catering to various lifestyles. Founded in 1999 and based in Greenwood Village, Colorado, eBags offers an extensive selection of products, including luggage, travel bags, handbags, backpacks, and fashion accessories such as cosmetic bags and wallets. The company features products for all demographics, including men, women, and children, and provides items designed for travel, fitness, and outdoor activities. eBags partners with well-known brands like Samsonite, JanSport, and The North Face, ensuring a broad selection of premium products. Committed to exceptional customer service, eBags offers personalized assistance and real-time order tracking to enhance the shopping experience. As of 2017, eBags operates as a subsidiary of Samsonite LLC.
OraMetrix, Inc. provides 3-D technology solutions for facilitating and improving the quality of orthodontic care. It offers an orthodontic treatment system that allows the use of precision digital tools throughout the diagnosis, treatment planning and monitoring, and arch wire customization processes of the orthodontic treatment. OraMetrix, Inc. was formerly known as Orthotel, Inc. The company was founded in 1998 and is based in Richardson, Texas with an additional office in Berlin, Germany.
Kona Medical, Inc. is a medical technology company based in Issaquah, Washington, founded in 2009 by Dr. Michael Gertner. The company specializes in developing a non-invasive ultrasound-based therapy system aimed at treating hypertension and related disorders. Its primary product, Surround Sound, is a hypertension therapy system that employs ultrasound imaging to precisely deliver focused ultrasound energy for renal denervation. This innovative approach targets the nerves associated with kidney function, offering a less invasive alternative for patients suffering from drug-resistant hypertension. By leveraging advancements in therapeutic focused ultrasound, Kona Medical seeks to improve treatment efficacy and reduce the health risks associated with high blood pressure.
Cianna Medical, Inc., a women’s health company, develops medical technologies for treating breast cancer. The company offers SAVI SCOUT, a wire-free radar localization solution for breast tumor localization; and SAVI Brachy, a solution to deliver a highly-precise dose of radiation only to the tissue where the cancer is likely to reoccur. It also offers BrachyBytes, an e-newsletter that features interviews with experts in breast brachytherapy. The company was incorporated in 2007 and is based in Aliso Viejo, California. As of November 13, 2018, Cianna Medical, Inc. operates as a subsidiary of Merit Medical Systems, Inc.
VisionSense Corp. designs and develops advanced 3D-HD visualization systems specifically for minimally invasive surgeries. Its flagship products include the Visionsense VSiii system, which utilizes a stereoscopic camera for various surgical applications such as neurosurgery, ENT procedures, arthroscopy, and laparoscopy. Additionally, the Visionsense Iridium system provides inter-operative infrared fluorescence visualization to enhance surgical precision. The company's innovative technology offers depth perception and high-resolution imaging, allowing surgeons to navigate complex procedures with greater confidence and control. VisionSense serves medical centers globally, focusing on areas including neurosurgery, plastic and reconstructive surgery, and tumor margin visualization. Founded in 1998 and headquartered in Philadelphia, Pennsylvania, VisionSense operates additional offices in New York and Petah-Tikva, Israel, and functions as a subsidiary of Medtronic plc.
Acsis, Inc. provides track and trace solutions for supply chain safety and security. The company offers process-automation platforms, pre-built processes and workflows, appliances, automated SAP integration, and serialization solutions, which automates data collection, streamlines manufacturing and distribution processes, and provides real-time access to supply chain information. Acsis is the leader in real-time track and traceability software that enables effective recall management, anti-diversion, and anti-counterfeiting measures for the CPG, Life Sciences and Chemical industries. By using Acsis ProducTrak software, organizations can track and trace products through its entire lifecycle - from the raw materials to finished goods. But true product visibility doesn't stop there. Tracking products in real-time at the item level through packaging, rework, repacking, adding to case and pallets, moving through the distribution channel, and finally to end user - such as a hospital or retail store - is what Acsis is known for. This type of visibility provides the data needed to pinpoint products for recall returns or highlights suspect areas in the distribution network where diversion or shrink is suspected. The company was founded in 1996 and is based in Marlton, New Jersey.
Gilt Groupe retails luxury goods online in the United States. It provides its members access to a range of merchandise that includes fashion for women, men, and children; home decor and unique activities in select cities and destinations. Gilt Groupe offers clothing, shoes, and accessories for men; and clothing, shoes, handbags, accessories, jewelry and watches, health and beauty products, and maternity wear for women. It also provides gear and equipment, feeding products, toys, games and books, furniture and decor, bedding and bath products, and maternity wear as well as clothing, shoes, and accessories for babies and kids. Moreover, Gilt Groupe offers furniture, bedding and bath products, rugs, lighting, decor and accessories, kitchen and dining products, luggage, gear and gadgets, pet accessories, and candles and holders for home. Alexandra Wilkis Wilson, Alexis Maybank, Dwight Merriman, Jason Binn, Kevin Ryan, and Michael Bryzek founded First Look in 2007 that later became Gilt Groupe. Gilt Groupe has its headquarters in New York City. It operates as a subsidiary of Hudson's Bay Company as of February 1, 2016.
OrSense Ltd. is a medical device company based in Petah-Tikva, Israel, specializing in non-invasive monitoring technologies for blood parameter measurement. Founded in 1996, the company develops solutions that enable continuous monitoring of hemoglobin, oxygen saturation, and pulse rate, utilizing its proprietary Occlusion Spectroscopy technology. The flagship product, the NBM 200MP system, allows for non-invasive measurement of multiple blood parameters, including hemoglobin, hematocrit, and low perfusion oximetry, making it suitable for use in hospitals, outpatient settings, and emergency services. OrSense's products have received CE approval and have been validated through testing on over 4,000 patients across various clinical environments in the U.S. and Europe. Their innovative approach addresses challenges such as poor peripheral perfusion and motion-induced noise, providing reliable and accurate monitoring solutions for healthcare providers.
Headquartered in San Diego, California, MedVantx is an innovative consumer medication management and delivery company committed to reducing costs and providing information to benefit patients, healthcare providers, payors, employers and manufacturers. Their state-of-the-art mail order pharmacy, operating in Sioux Falls, South Dakota, is licensed in all 50 states and serves as a full line mail order prescription drug and information provider to consumers. Their 35,000 square foot facility recently underwent major upgrades and now meets over 200 cGMP-level quality standards and can properly handle all pharmaceuticals requiring Cold Chain processing. The MedStart Connect program is operational in a number of states including Arizona, California, Florida, Georgia, Massachusetts, Minnesota, New Jersey, New York, North Carolina, Ohio, Oregon, Pennsylvania, Rhode Island and South Carolina, and serves approximately 4,000 top-decile primary care prescribers. They continue to expand in additional states. MedVantx was recognized by Inc. Magazine in 2009 as the fastest growing privately held healthcare company in the country and 13th fastest overall.
VisionCare Ophthalmic Technologies, Inc. is a specialty medical device company based in Saratoga, California, focused on the research, development, manufacture, and marketing of innovative implantable ophthalmic devices. The company primarily aims to enhance vision and quality of life for individuals suffering from untreatable retinal disorders, particularly end-stage age-related macular degeneration (AMD), which is a leading cause of blindness among older Americans. VisionCare's flagship product is the Implantable Miniature Telescope, the first FDA-approved device designed to improve vision in patients with advanced AMD. This telescope implant is a critical component of the CentraSight treatment program, which guides patients through the processes of diagnosis, surgical evaluation, and postoperative care. Founded in 1997, VisionCare is dedicated to helping patients reconnect with their daily lives and activities through its advanced visual prosthetic technologies.
VaxInnate is a biotechnology company based in Cranbury, New Jersey, founded in 2002. The company specializes in developing vaccines aimed at combating diseases such as influenza, malaria, dengue, papillomavirus, and respiratory syncytial virus. VaxInnate employs a unique approach by genetically fusing vaccine antigens with bacterial protein flagellin, which enhances the immunogenicity and efficacy of the vaccines. This innovative method facilitates quicker patient treatment initiation and increases the likelihood of successful outcomes. Through its focus on healthcare and health diagnostics, VaxInnate aims to address significant public health challenges with its advanced vaccine solutions.
InnoPath specializes in mobile device management technology, providing software solutions for wireless operators and mobile device manufacturers. The company's offerings, including mobileUpdate and activeCare2, enable remote updates, diagnostics, and repairs of mobile devices over-the-air. This technology helps avoid device recalls and returns, decreases the frequency of support calls, and enhances first call resolution for issues related to Android and iOS devices. By improving operational efficiency and user experience, InnoPath contributes to increased subscriber satisfaction in an ever-connected mobile landscape.
Vidyo, Inc. specializes in high-definition video conferencing software that facilitates universal visual communication. Its suite of products includes VidyoDesktop, which allows users on Windows, Mac, and Linux to engage in video conferences from various locations, and VidyoWeb, a browser extension enabling conference participation from desktop and laptop computers. Additionally, VidyoRoom Solutions offer tailored in-office video conferencing experiences for hybrid teams, while VidyoMobile provides high-quality conferencing capabilities for mobile devices. VidyoSlate allows users to share and annotate content during conferences. The company serves diverse sectors including healthcare, education, government, and enterprise, emphasizing the importance of video communication in enhancing productivity and collaboration. Founded in 2005 and headquartered in Hackensack, New Jersey, Vidyo has expanded its presence worldwide with offices in multiple countries. As of 2019, it operates as a subsidiary of Enghouse Systems Limited.
Circadence Corporation specializes in optimizing network infrastructure and enhancing cybersecurity readiness. The company offers a range of products, including the MVO 1200 WAN Optimization suite, which improves application performance and user experience, as well as various MVO appliances for managing remote network connections. Their offerings extend to both Windows and Linux platforms, alongside inCyt, a cybersecurity awareness training solution. Circadence is recognized for its cyber range solutions and learning platforms, designed to provide immersive training experiences that address current security challenges for enterprises, government agencies, and academic institutions. The company emphasizes innovation and adaptability in training methods to develop cybersecurity skills among both novice and experienced professionals. Founded in 1993 and based in Boulder, Colorado, Circadence also has additional offices in Tupelo, Mississippi; McLean, Virginia; and Littleton, Colorado.
Founded in 1999, Mblox is a leading provider of mobile messaging solutions, specializing in Application-to-Person (A2P) messaging. The company maintains over 100 direct carrier relationships, which enables it to process approximately 7 billion mobile messages annually for more than 4,000 customers across various sectors, including financial services, government, transportation, logistics, retail, and advertising. Mblox's cloud-based platform is designed to accommodate businesses of all sizes, from startups to large multinational corporations. The company is known for its reliable service and offers 24/7 email support from an in-house team of experts, along with various support packages tailored to meet individual business needs.
Mitralign is a privately held company based in a suburb of Boston, Massachusetts, focused on developing a catheter-based technology for the treatment of functional mitral regurgitation. The company has created an innovative system that mimics surgical annuloplasty by delivering surgical implants directly into the mitral annulus via a catheter. This process involves cinching the implants together to decrease the size of the mitral valve annulus and the valve opening. Mitralign's technology aims to provide a less invasive option for managing this life-threatening cardiac condition, enabling healthcare providers to effectively treat symptomatic functional mitral regurgitation through tissue-plication. The company is supported by prominent venture capitalists and has attracted investments from major cardiovascular device firms.
Radius Health, Inc. is a biopharmaceutical company dedicated to developing and commercializing therapeutic solutions for osteoporosis and oncology. The company markets TYMLOS, an anabolic agent specifically for postmenopausal women with osteoporosis. It is advancing several clinical programs, including abaloparatide-SC, currently in phase 3 trials for treating osteoporosis in men, and a short-wear-time transdermal patch for postmenopausal women. Additionally, Radius is developing Elacestrant, a selective estrogen receptor degrader in phase 3 studies for hormone receptor-positive breast cancer, and RAD140, a selective androgen receptor modulator in phase 1A trials for metastatic breast cancer. Founded in 2003 and based in Waltham, Massachusetts, Radius Health collaborates with various organizations, including 3M Company and Duke University, to enhance its research and development efforts in bone health and women's health issues.
Arcadia Biosciences is an agricultural technology company that focuses on developing crop productivity traits primarily in hemp, wheat, and soybean. Its innovations aim to enhance farm economics by improving crop performance and the value of agricultural products for food, health, and industrial applications. Key offerings include GoodHemp, a line of non-GMO hemp seed varieties, GoodWheat, which transforms wheat into a functional food, and HB4, a drought and herbicide tolerant soybean trait. The company employs advanced screening, breeding, and biotechnology techniques to promote agricultural efficiency and environmental sustainability. Arcadia has established partnerships with several organizations, including Ardent Mills and Corteva AgriScience, and operates in the United States, Canada, Africa, and India. Founded in 2002 and headquartered in Davis, California, Arcadia has granted over 70 technology licenses globally to major seed and consumer product companies.
OrSense Ltd. is a medical device company based in Petah-Tikva, Israel, specializing in non-invasive monitoring technologies for blood parameter measurement. Founded in 1996, the company develops solutions that enable continuous monitoring of hemoglobin, oxygen saturation, and pulse rate, utilizing its proprietary Occlusion Spectroscopy technology. The flagship product, the NBM 200MP system, allows for non-invasive measurement of multiple blood parameters, including hemoglobin, hematocrit, and low perfusion oximetry, making it suitable for use in hospitals, outpatient settings, and emergency services. OrSense's products have received CE approval and have been validated through testing on over 4,000 patients across various clinical environments in the U.S. and Europe. Their innovative approach addresses challenges such as poor peripheral perfusion and motion-induced noise, providing reliable and accurate monitoring solutions for healthcare providers.
Transonic Combustion, founded in 2006 and headquartered in Camarillo, California, specializes in advanced fuel injection systems designed to enhance the efficiency of modern automotive engines. The company's TSCi™ fuel delivery technology is tailored for global automotive manufacturers, aiming to improve fuel efficiency and performance in various engine platforms. Transonic Combustion is backed by notable venture capital firms, including Venrock, Khosla Ventures, Rustic Canyon, and Saints Capital, indicating strong investor confidence in its innovative approach to fuel technology.
VisionSense Corp. designs and develops advanced 3D-HD visualization systems specifically for minimally invasive surgeries. Its flagship products include the Visionsense VSiii system, which utilizes a stereoscopic camera for various surgical applications such as neurosurgery, ENT procedures, arthroscopy, and laparoscopy. Additionally, the Visionsense Iridium system provides inter-operative infrared fluorescence visualization to enhance surgical precision. The company's innovative technology offers depth perception and high-resolution imaging, allowing surgeons to navigate complex procedures with greater confidence and control. VisionSense serves medical centers globally, focusing on areas including neurosurgery, plastic and reconstructive surgery, and tumor margin visualization. Founded in 1998 and headquartered in Philadelphia, Pennsylvania, VisionSense operates additional offices in New York and Petah-Tikva, Israel, and functions as a subsidiary of Medtronic plc.
Actelis Networks is the leading provider of high performance, scalable broadband over copper solutions to Telco, Mobile, and IoT networks. Actelis turns copper into a strategic asset that enables delivering reliable, high-speed Ethernet services and broadband access to more places and devices more quickly, easily, and cost-effectively than can be done by using fiber optics or microwave.
The company was founded in 1998 and headquartered in Fremont, California.
Xtime is a prominent provider of cloud-based Customer Relationship Management (CRM) and scheduling software specifically designed for automotive service departments in North America. With a customer base exceeding 3,000 dealerships and the registration of over 1 million customers, Xtime processes more than 1 million appointments each month. The company partners with leading global automotive manufacturers, including Lexus, Toyota, BMW, Mercedes-Benz, and Nissan, and is the preferred choice for major dealership groups such as AutoNation and Group 1 Automotive. By offering integrated software solutions that streamline marketing, sales, service, and operational workflows, Xtime enhances the customer experience in the retail automotive industry. Headquartered in Redwood Shores, California, Xtime continues to be a key player in automotive service technology.
NComputing, Inc. is a provider of client virtualization solutions. Through a formula of simplicity, performance and value, NComputing’s solutions serve larger scale and mid-market enterprises, small and medium business (SMB) and education customers, and other verticals markets including healthcare, finance, manufacturing, and government. The Company’s virtualization solutions enable users on any device and from any location to access their own personalized desktops, applications and data, regardless of its physical location. NComputing’s technology platform is based on core technologies including its UXP transmission protocols, virtualization server, application awareness and thin client devices. NComputing has approximately 4 million seats installed among more than 60,000 customers. The company was founded in 2003 and is based in Santa Clara, California.
OrSense Ltd. is a medical device company based in Petah-Tikva, Israel, specializing in non-invasive monitoring technologies for blood parameter measurement. Founded in 1996, the company develops solutions that enable continuous monitoring of hemoglobin, oxygen saturation, and pulse rate, utilizing its proprietary Occlusion Spectroscopy technology. The flagship product, the NBM 200MP system, allows for non-invasive measurement of multiple blood parameters, including hemoglobin, hematocrit, and low perfusion oximetry, making it suitable for use in hospitals, outpatient settings, and emergency services. OrSense's products have received CE approval and have been validated through testing on over 4,000 patients across various clinical environments in the U.S. and Europe. Their innovative approach addresses challenges such as poor peripheral perfusion and motion-induced noise, providing reliable and accurate monitoring solutions for healthcare providers.
BioSET, Inc., founded in 2001 and based in Rockville, Maryland, specializes in the research and development of synthetic bioactive peptides for medical applications. The company focuses on creating proprietary therapeutic peptides and implantable devices designed to enhance bone and soft tissue repair, particularly in orthobiologics. Its flagship product, Amplex, is an implantable device that combines a peptide with a synthetic ceramic scaffold, serving as a surgical bone graft implant for various spinal and orthopedic surgeries, including lumbar degenerative disc disease and foot and ankle fusion procedures. Additionally, BioSET develops products for sports medicine and offers peptide signaling molecules along with diverse scaffold biomaterials to support musculoskeletal applications, including trauma and fracture repair. As of February 2015, BioSET operates as a subsidiary of Ferring Pharmaceuticals Inc.
Vidyo, Inc. specializes in high-definition video conferencing software that facilitates universal visual communication. Its suite of products includes VidyoDesktop, which allows users on Windows, Mac, and Linux to engage in video conferences from various locations, and VidyoWeb, a browser extension enabling conference participation from desktop and laptop computers. Additionally, VidyoRoom Solutions offer tailored in-office video conferencing experiences for hybrid teams, while VidyoMobile provides high-quality conferencing capabilities for mobile devices. VidyoSlate allows users to share and annotate content during conferences. The company serves diverse sectors including healthcare, education, government, and enterprise, emphasizing the importance of video communication in enhancing productivity and collaboration. Founded in 2005 and headquartered in Hackensack, New Jersey, Vidyo has expanded its presence worldwide with offices in multiple countries. As of 2019, it operates as a subsidiary of Enghouse Systems Limited.
Art.com is an online platform founded in 1998 and headquartered in San Bruno, California, specializing in the sale of wall art and decorative items. The company offers a wide range of products, including high-quality wall art, limited-edition prints, hand-painted originals, and home accessories. It serves various retail partners, such as specialty retailers, museums, hotels, and interior designers, facilitating access to innovative art and décor solutions. Through its platform, Art.com enables customers to explore their artistic preferences and express themselves through a diverse selection of artwork.
Xtime is a prominent provider of cloud-based Customer Relationship Management (CRM) and scheduling software specifically designed for automotive service departments in North America. With a customer base exceeding 3,000 dealerships and the registration of over 1 million customers, Xtime processes more than 1 million appointments each month. The company partners with leading global automotive manufacturers, including Lexus, Toyota, BMW, Mercedes-Benz, and Nissan, and is the preferred choice for major dealership groups such as AutoNation and Group 1 Automotive. By offering integrated software solutions that streamline marketing, sales, service, and operational workflows, Xtime enhances the customer experience in the retail automotive industry. Headquartered in Redwood Shores, California, Xtime continues to be a key player in automotive service technology.
Transonic Combustion, founded in 2006 and headquartered in Camarillo, California, specializes in advanced fuel injection systems designed to enhance the efficiency of modern automotive engines. The company's TSCi™ fuel delivery technology is tailored for global automotive manufacturers, aiming to improve fuel efficiency and performance in various engine platforms. Transonic Combustion is backed by notable venture capital firms, including Venrock, Khosla Ventures, Rustic Canyon, and Saints Capital, indicating strong investor confidence in its innovative approach to fuel technology.
Mitralign is a privately held company based in a suburb of Boston, Massachusetts, focused on developing a catheter-based technology for the treatment of functional mitral regurgitation. The company has created an innovative system that mimics surgical annuloplasty by delivering surgical implants directly into the mitral annulus via a catheter. This process involves cinching the implants together to decrease the size of the mitral valve annulus and the valve opening. Mitralign's technology aims to provide a less invasive option for managing this life-threatening cardiac condition, enabling healthcare providers to effectively treat symptomatic functional mitral regurgitation through tissue-plication. The company is supported by prominent venture capitalists and has attracted investments from major cardiovascular device firms.
Solace Therapeutics, Inc. develops non-surgical office based treatments for unexpected bladder leaks in women. The company provides Vesair Bladder Control System, a non-surgical device that floats within the urinary bladder to eliminate and reduce involuntary urinary leakage. Its Vesair Bladder Control System is a non-surgical alternative to involuntary urinary leakage and a lightweight device to address the cause of stress urinary incontinence. The company was incorporated in 2002 and is based in Framingham, Massachusetts.
Private Equity Round in 2011
Radius Health, Inc. is a biopharmaceutical company dedicated to developing and commercializing therapeutic solutions for osteoporosis and oncology. The company markets TYMLOS, an anabolic agent specifically for postmenopausal women with osteoporosis. It is advancing several clinical programs, including abaloparatide-SC, currently in phase 3 trials for treating osteoporosis in men, and a short-wear-time transdermal patch for postmenopausal women. Additionally, Radius is developing Elacestrant, a selective estrogen receptor degrader in phase 3 studies for hormone receptor-positive breast cancer, and RAD140, a selective androgen receptor modulator in phase 1A trials for metastatic breast cancer. Founded in 2003 and based in Waltham, Massachusetts, Radius Health collaborates with various organizations, including 3M Company and Duke University, to enhance its research and development efforts in bone health and women's health issues.
CircuLite is a cardiovascular device company focused on transforming the treatment of heart failure through the development of minimally-invasive micro-pumps for long-term partial circulatory support. The company’s proprietary micro-pump platform allows for the creation of small devices that can be implanted in a manner similar to a pacemaker, using endovascular or minimally-invasive surgical techniques. By supplementing a patient's natural heart function, CircuLite's devices aim to provide a proactive and lower-risk treatment option, potentially enhancing the quality of life for millions of individuals suffering from chronic heart failure and their families.
Radius Health, Inc. is a biopharmaceutical company dedicated to developing and commercializing therapeutic solutions for osteoporosis and oncology. The company markets TYMLOS, an anabolic agent specifically for postmenopausal women with osteoporosis. It is advancing several clinical programs, including abaloparatide-SC, currently in phase 3 trials for treating osteoporosis in men, and a short-wear-time transdermal patch for postmenopausal women. Additionally, Radius is developing Elacestrant, a selective estrogen receptor degrader in phase 3 studies for hormone receptor-positive breast cancer, and RAD140, a selective androgen receptor modulator in phase 1A trials for metastatic breast cancer. Founded in 2003 and based in Waltham, Massachusetts, Radius Health collaborates with various organizations, including 3M Company and Duke University, to enhance its research and development efforts in bone health and women's health issues.
Cianna Medical, Inc., a women’s health company, develops medical technologies for treating breast cancer. The company offers SAVI SCOUT, a wire-free radar localization solution for breast tumor localization; and SAVI Brachy, a solution to deliver a highly-precise dose of radiation only to the tissue where the cancer is likely to reoccur. It also offers BrachyBytes, an e-newsletter that features interviews with experts in breast brachytherapy. The company was incorporated in 2007 and is based in Aliso Viejo, California. As of November 13, 2018, Cianna Medical, Inc. operates as a subsidiary of Merit Medical Systems, Inc.
AngioScore Inc. is a company that specializes in the development, manufacturing, and marketing of innovative medical devices for the treatment of cardiovascular and peripheral artery diseases. Its primary product, the AngioSculpt Scoring Balloon Catheter, is designed to improve the efficacy of conventional angioplasty procedures. This catheter features a semi-compliant balloon combined with a unique nitinol scoring element, aimed at overcoming the limitations of traditional balloon catheters. By focusing on enhancing endovascular therapy tools, AngioScore addresses critical needs within the interventional market, contributing to advancements in the treatment of vascular diseases.
VisionCare Ophthalmic Technologies, Inc. is a specialty medical device company based in Saratoga, California, focused on the research, development, manufacture, and marketing of innovative implantable ophthalmic devices. The company primarily aims to enhance vision and quality of life for individuals suffering from untreatable retinal disorders, particularly end-stage age-related macular degeneration (AMD), which is a leading cause of blindness among older Americans. VisionCare's flagship product is the Implantable Miniature Telescope, the first FDA-approved device designed to improve vision in patients with advanced AMD. This telescope implant is a critical component of the CentraSight treatment program, which guides patients through the processes of diagnosis, surgical evaluation, and postoperative care. Founded in 1997, VisionCare is dedicated to helping patients reconnect with their daily lives and activities through its advanced visual prosthetic technologies.
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.
Angie's List, Inc. operates a consumer review service and e-commerce marketplace in the United States, allowing individuals to research and purchase local services for home, health, and automotive needs. The platform features over 10 million verified reviews, covering more than 700 categories, where consumers can rate and review service providers based on their experiences. Service providers can respond to reviews and engage with potential customers. Angie's List also offers group coupons in select markets and provides conflict resolution services. Membership to the platform is now free, with optional paid plans that offer additional benefits. Founded in 1995 and headquartered in Indianapolis, Indiana, Angie's List, Inc. was previously known as Brownstone Publishing, LLC and rebranded in 2010. It is a subsidiary of ANGI Homeservices Inc.
Laureate Pharma, Inc., a contract manufacturing organization, provides development and cGMP manufacturing services. It focuses on mammalian cell based monoclonal antibody and recombinant protein production for clinical and commercial supply. The company's biopharmaceutical production/biotherapeutics production services include cGMP production and purification, protein modification and conjugation, formulation and aseptic filling into vials and finishing, upstream and downstream process development, Cell Line Optimization, medium optimization studies and adapting cells to protein-free medium, pilot-scale bioreactor runs, and product formulation development. Its services also comprise transfection, cloning, and selection to create new cell lines; analytical method transfer, development, and qualification; and preclinical production, monoclonal antibody production, and clinical trials manufacturing. Laureate Pharma supports the development and commercialization of biopharmaceutical, drug, and diagnostic products for pharmaceutical, diagnostic, and biotech companies. The company was formerly known as Bard Biopharma L.P. and changed its name to Laureate Pharma, Inc. in 2002. The company is headquartered in Princeton, New Jersey.
Serious Energy, Inc. specializes in designing and providing energy-efficient products for buildings, aimed at reducing energy consumption for both owners and occupants. The company's offerings include the iWindow, a retrofit glass system for commercial applications; SeriousEnergy Manager, a cloud-based energy management platform; and various products like SeriousWindows, SeriousGlass, and QuietRock, which enhance energy performance and soundproofing in different environments such as residential, commercial, and institutional settings. Founded in 1977 and located in Sunnyvale, California, Serious Energy operates manufacturing plants in Newark, California; Boulder, Colorado; and Vandergrift, Pennsylvania, along with a dedicated research and development facility. The company, formerly known as Serious Materials, has received multiple accolades for its innovative contributions to sustainable building materials, highlighting its commitment to reducing the environmental impact of the built environment.
Incline Therapeutics is a privately-held specialty pharmaceutical company that focuses on the development of IONSYS, a fentanyl iontophoretic transdermal system designed for adult inpatients needing opioid pain relief following surgery. The company is dedicated to creating a compact, disposable, needleless Patient-Controlled Analgesia system that facilitates the short-term management of postoperative pain. Incline Therapeutics is backed by prominent life science venture capital firms and is led by a management team with extensive experience in the pharmaceutical and medical device sectors.
KXEN, Inc. is a data mining automation company that specializes in business analytics software tailored for customer lifecycle analytics, supply chain analytics, and business intelligence. The company offers a range of software packages that facilitate various data manipulations, including classification, regression, and segmentation, as well as single-purpose analysis applications for forecasting and market basket analysis. KXEN's Analytic Framework integrates multiple components to provide comprehensive data mining automation solutions. In addition to its software offerings, KXEN provides technical support services, education programs, and consulting services to assist clients in utilizing their products effectively. The company primarily serves clients in the financial services, telecommunications, and retail sectors and distributes its products through systems integrators, software vendors, and original equipment manufacturers globally. Founded in 1998 and headquartered in San Francisco, KXEN has additional offices in Canada, the United Kingdom, and France, and maintains strategic partnerships with major technology firms.
MicroCHIPS Biotech, Inc. specializes in developing a microchip-based implant designed for drug delivery applications across various therapeutic areas, including osteoporosis, diabetes, multiple sclerosis, women’s contraception, and pain management. This innovative implant can store and release precise doses of medication over extended periods, offering an alternative to traditional therapies that rely on frequent injections. The implant is surgically placed under the skin during a minimally invasive procedure and can be wirelessly activated or deactivated by healthcare providers or patients. Additionally, the device allows for real-time adjustments to the drug dosage and frequency, catering to the specific needs of each patient. Established in 1999 and headquartered in Lexington, Massachusetts, MicroCHIPS operates as a subsidiary of Daré Bioscience, Inc.
Envivio is a leading provider of software-based solutions for multi-screen video processing and delivery, enabling seamless access to video content across various devices and networks. With over a decade of experience in developing innovative video convergence solutions, the company serves more than 300 customers worldwide, including major mobile operators, broadband providers, and cable operators. Envivio offers a range of products and services, including video compression, direct-to-consumer distribution, advertising and content personalization, as well as cloud DVR and video delivery platforms. Headquartered in South San Francisco, California, Envivio operates globally with offices in several countries, including France, England, China, Singapore, and Japan. The company's mission is to enhance the ability of service providers, content owners, and broadcasters to create and deliver immersive media experiences.
Coapt Systems, Inc. specializes in the design, development, and manufacturing of bio-absorbable implants intended for soft tissue fixation in facial cosmetic surgery. Its product offerings include various fixation devices such as the ENDOTINE Forehead 3.0 and ENDOTINE Midface ST 4.5, which are employed in procedures like forehead lifts, brow lifts, and midface suspensions. The company also provides surgical instruments and tools, including insertion kits and manual drills, to facilitate the use of its implants. Coapt Systems aims to support surgeons in achieving effective and secure tissue fixation during surgical procedures, enhancing outcomes for patients undergoing cosmetic interventions.
Actelis Networks is the leading provider of high performance, scalable broadband over copper solutions to Telco, Mobile, and IoT networks. Actelis turns copper into a strategic asset that enables delivering reliable, high-speed Ethernet services and broadband access to more places and devices more quickly, easily, and cost-effectively than can be done by using fiber optics or microwave.
The company was founded in 1998 and headquartered in Fremont, California.
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.
Broncus Medical develops innovative diagnostic and therapeutic navigation technologies aimed at treating lung diseases. The company offers a range of products, including the Archimedes System, which features bronchoscopic trans-parenchymal needle access for virtual bronchoscopic planning and navigation, and the Lungpoint Virtual Bronchoscopic Navigation system that enables real-time navigation within the lungs for biopsy procedures. Additionally, Broncus is advancing its Exhale product line, which includes the Airway Bypass procedure, a minimally-invasive treatment for homogeneous emphysema, a prevalent form of the disease. The company is currently conducting the pivotal EASE Trial to evaluate this treatment. Founded in 1997 and originally named Broncus Technologies, the company is headquartered in San Jose, California, with additional operations in Shanghai, China, and Mountain View, California. Broncus Medical focuses on addressing the unmet medical needs in interventional pulmonology, improving the diagnosis and treatment of lung cancer and chronic obstructive pulmonary disease (COPD).
Private Equity Round in 2008
Arcadia Biosciences is an agricultural technology company that focuses on developing crop productivity traits primarily in hemp, wheat, and soybean. Its innovations aim to enhance farm economics by improving crop performance and the value of agricultural products for food, health, and industrial applications. Key offerings include GoodHemp, a line of non-GMO hemp seed varieties, GoodWheat, which transforms wheat into a functional food, and HB4, a drought and herbicide tolerant soybean trait. The company employs advanced screening, breeding, and biotechnology techniques to promote agricultural efficiency and environmental sustainability. Arcadia has established partnerships with several organizations, including Ardent Mills and Corteva AgriScience, and operates in the United States, Canada, Africa, and India. Founded in 2002 and headquartered in Davis, California, Arcadia has granted over 70 technology licenses globally to major seed and consumer product companies.
Envivio is a leading provider of software-based solutions for multi-screen video processing and delivery, enabling seamless access to video content across various devices and networks. With over a decade of experience in developing innovative video convergence solutions, the company serves more than 300 customers worldwide, including major mobile operators, broadband providers, and cable operators. Envivio offers a range of products and services, including video compression, direct-to-consumer distribution, advertising and content personalization, as well as cloud DVR and video delivery platforms. Headquartered in South San Francisco, California, Envivio operates globally with offices in several countries, including France, England, China, Singapore, and Japan. The company's mission is to enhance the ability of service providers, content owners, and broadcasters to create and deliver immersive media experiences.
Alliance Consulting Group is a strategy consulting firm located in Boston, Massachusetts. Founded in 1986, Alliance has pioneered and perfected a unique approach to strategy development that consistently delivers exceptional value to their clients. At Alliance, they share a common vision about what a consulting firm should be. They are passionate about the rigor and creativity in their work, and they enjoy the excitement of growing their own company. The result is a truly superior strategy service for their clients and a fun growth environment for their staff.
Acsis, Inc. provides track and trace solutions for supply chain safety and security. The company offers process-automation platforms, pre-built processes and workflows, appliances, automated SAP integration, and serialization solutions, which automates data collection, streamlines manufacturing and distribution processes, and provides real-time access to supply chain information. Acsis is the leader in real-time track and traceability software that enables effective recall management, anti-diversion, and anti-counterfeiting measures for the CPG, Life Sciences and Chemical industries. By using Acsis ProducTrak software, organizations can track and trace products through its entire lifecycle - from the raw materials to finished goods. But true product visibility doesn't stop there. Tracking products in real-time at the item level through packaging, rework, repacking, adding to case and pallets, moving through the distribution channel, and finally to end user - such as a hospital or retail store - is what Acsis is known for. This type of visibility provides the data needed to pinpoint products for recall returns or highlights suspect areas in the distribution network where diversion or shrink is suspected. The company was founded in 1996 and is based in Marlton, New Jersey.
LifeMasters Supported SelfCare, one of the nation's leading disease management companies, provides programs and services that create health partnerships among individuals, their physicians and payors.
Zonare Medical Systems, Inc. specializes in the development and manufacturing of compact ultrasound systems utilized for diagnostic imaging across various clinical applications. Central to its offerings is the z.one ultrasound system, which incorporates the proprietary Zone Sonography technology, allowing for enhanced data acquisition and image formation. This technology enables clients to maintain their ultrasound systems while also integrating new clinical applications and advanced imaging capabilities. Zonare Medical markets its products through a direct sales force in the United States and a mix of distributors and direct sales personnel in around 40 international markets. Founded in 1999 and headquartered in Mountain View, California, the company aims to provide innovative and accessible medical technologies tailored to the needs of healthcare professionals.
Zonare Medical Systems, Inc. specializes in the development and manufacturing of compact ultrasound systems utilized for diagnostic imaging across various clinical applications. Central to its offerings is the z.one ultrasound system, which incorporates the proprietary Zone Sonography technology, allowing for enhanced data acquisition and image formation. This technology enables clients to maintain their ultrasound systems while also integrating new clinical applications and advanced imaging capabilities. Zonare Medical markets its products through a direct sales force in the United States and a mix of distributors and direct sales personnel in around 40 international markets. Founded in 1999 and headquartered in Mountain View, California, the company aims to provide innovative and accessible medical technologies tailored to the needs of healthcare professionals.
Blip is an online media platform that offers users access to a variety of video clips and programs focused on media and entertainment. The platform features content across multiple categories, including general entertainment, comedy, music, drama, television, food, and video games. It organizes its offerings into segments such as editors' picks, current trends, and new episodes. Additionally, Blip provides producers with tools to host, distribute, and monetize their web series. Founded in 2005 by Charles Hope and Jared Klett, Blip is headquartered in New York City.
SideStep is a metasearch engine specializing in travel, which consolidates results from over 200 travel websites to help users find the best deals. It offers access to information on more than 150,000 hotels and 600 airlines globally. The company generates revenue through advertising and referral fees. Recently, SideStep has expanded its services by acquiring TripUp, a social travel network, and TravelPost.com, a hotel ratings platform, aiming to enhance its position in the online travel market. Additionally, SideStep has developed applications for Facebook, including a trip planning service that has attracted over 150,000 users. The company was acquired by Kayak in December 2007, further solidifying its presence in the competitive metasearch landscape.
Forte Design Systems, Inc. provides software products. The company offers Cynthesizer, a silicon-proven behavioral synthesis technology that generates production-quality RTL. Its Cynthesizer is used to develop products by various electronic companies and semiconductor suppliers. Forte's synthesis technology allows design teams creating electronic systems from algorithmic designs using ASICs, FPGAs, and SoCs to reduce their overall design and verification time. It serves consumer electronics, digital media, wireless communications and infrastructure, and security industries. Forte has direct sales representation in North America, Europe, and Japan with a value added reseller relationship established in Korea. Forte Design Systems, Inc. was founded in 2001 and is headquartered in San Jose, California with additional offices in Massachusetts, Minnesota, Pennsylvania, Texas, and Washington, as well as in France and Japan.
SEVEN Networks, Inc. specializes in developing software solutions focused on device-centric mobile traffic management and analytics for wireless carriers globally. The company's flagship product line, Open Channel, enhances mobile traffic visibility and optimization, allowing carriers to regain control over data traffic and improve the end-user experience. SEVEN also offers mobile applications that simplify social messaging for consumers while providing carriers with various messaging tools. Additionally, its Push Technology and Push Notifications services reduce network traffic compared to traditional polling methods, resulting in increased user engagement with mobile applications. The company provides technical support and professional services, including solution integration and managed services. Founded in 2000 and headquartered in San Carlos, California, SEVEN Networks has established a strong presence worldwide, supported by a portfolio of over three hundred patents, reflecting its expertise in both mobile applications and network integration.
It started with a simple observation: physicians need easier access to patient information. Since then, PatientKeeper has grown to become the leading physician information system provider. And for good reason. Since 1998, they've helped healthcare organizations cost-effectively deliver information where it's needed most to enhance patient care and safety, reduce costs, improve staff productivity and increase revenue. They offer the industry's only suite of applications that support physicians throughout their entire day — enabling them to review electronic patient records...write prescriptions...enter charges...dictate notes...document encounters...place orders...even consult with other caregivers — wherever they are. Their software addresses physician needs across virtually any device — ranging from handhelds to Smartphones to tablets, to laptops to desktop computers, so that whether they're reviewing test results in their office, in the car or at the bedside, they're covered. PatientKeeper customers can start with just a single application and add new capabilities as needed — with PatientKeeper all their applications are tightly integrated with each other. And because their platform integrates with existing healthcare systems, there's no need to replace legacy systems.
Novera Optics
Venture Round in 2006
Novera Optics develops optical access solutions. Its PON optical solutions enable equipment vendors and service providers to address fiber-to-the-building, fiber-to-the-curb extensions, multi-dwelling and multi-tenant units, remote terminals, and the central office markets. The company offers Wavelength Division Multiplexed-Passive Optical Networks (WDM-PON), an access and transport platform, which provides an architecture for access networks that enables service providers to deliver voice, data, video, and wireless services.
NextWeb is a wireless Internet service provider, providing high-speed service to more than 1000 enterprise customers in Northern and Southern California. NextWeb's service is available in over 50,000 business locations in more than 60 cities. Typically installed in just three to seven days, NextWeb's service is 30 percent faster than a T1 at approximately half the cost, easily scaling to six times the speed of a T1.