Early Stage Partners

Juventas Therapeutics is a privately-held clinical-stage biotechnology company developing regenerative therapies. Founded in 2007, it focuses on treating life-threatening diseases using non-viral gene therapies that activate natural processes to repair the body.

LineStream Technologies, Inc. specializes in the development of motor, motion, and industrial control software aimed at enhancing the performance of automated products and processes. Established in 2006 and headquartered in Cleveland, Ohio, the company offers embedded software solutions that can be integrated into a wide array of products, from household appliances to advanced manufacturing equipment. LineStream Technologies' software is designed to actively mitigate process disturbances, thereby improving system performance and simplifying control and tuning for users. The company was formerly known as ADRC Technologies, Inc. before rebranding in March 2010.

Simbionix USA Corporation specializes in simulation, training, and education solutions for medical professionals and the healthcare industry. Founded in 1997 and based in Cleveland, Ohio, with a research and development center in Israel, the company offers a range of training simulators for laparoscopic surgery, endovascular procedures, endoscopy, bronchoscopy, and endourology. Its products include a Learning Management System that tracks and reports performance and the PROcedure Rehearsal Studio, which enables clinicians to create patient-specific 3D virtual anatomical models from CT scans. Simbionix distributes its solutions globally, serving surgeons, interventionists, nurses, and technicians across the Middle East, Gulf countries, South America, the Asia-Pacific, and Europe. The company's commitment lies in enhancing clinical performance and optimizing procedural outcomes through innovative education and collaboration.

Juventas Therapeutics is a privately-held clinical-stage biotechnology company developing regenerative therapies. Founded in 2007, it focuses on treating life-threatening diseases using non-viral gene therapies that activate natural processes to repair the body.

Arisdyne Systems, Inc., based in Cleveland, Ohio, specializes in producing advanced process improvement equipment. The company's portfolio includes high shear force, high temperature, and hydrodynamic cavitation equipment designed for various applications such as enhancing yield in ethanol production from starch and fiber, reducing chemical consumption in vegetable oil processing, and improving waste water treatment efficiency. Arisdyne Systems' technology utilizes controlled flow cavitation to generate energy peaks that efficiently reduce particle size, disrupt cell structures, and accelerate chemical reactions. The company's equipment is known for its small footprint and scalability, making it suitable for both laboratory settings and large-scale industrial applications. Originally incorporated in 2006 as FST Fuel Technologies, Inc., the company rebranded to Arisdyne Systems, Inc. in January 2008 and operates as a subsidiary of Five Star Technologies, Inc.

LineStream Technologies, Inc. specializes in the development of motor, motion, and industrial control software aimed at enhancing the performance of automated products and processes. Established in 2006 and headquartered in Cleveland, Ohio, the company offers embedded software solutions that can be integrated into a wide array of products, from household appliances to advanced manufacturing equipment. LineStream Technologies' software is designed to actively mitigate process disturbances, thereby improving system performance and simplifying control and tuning for users. The company was formerly known as ADRC Technologies, Inc. before rebranding in March 2010.

Imalux Corporation, an Ohio medical device company, is positioned to become the worldwide leader in the commercializationPhoto of medical imaging equipment and devices based on its proprietary Optical Coherence Tomography (OCT) technology. The Company’s products provide real-time, high spatial resolution imaging at the point-of-care in a variety of medical applications. OCT is a new imaging modality for visualization of tissue microstructure, especially in anatomical areas with stratified tissue. It has the ability to detect near-surface tissue abnormalities indicative of disease, which established imaging modalities might not detect. Many diseases, including cancer, are associated with superficial tissue structure disruption. Today, there is no commercialized in vivo method to visualize this tissue structure alteration; clinicians must do a biopsy and an ex vivo histopathological review using a conventional microscope. Imalux OCT products can be used to visualize structural disruptions in vivo at the point of care.

Blue Spark Technologies develops power source solutions for battery-powered printed electronic systems. It designs and provides thin, printable batteries and flexible, printed power sources for OEMs and system integrators across industries including food and beverage, pharmaceuticals, healthcare and medical diagnostics, smart cards, RF sensors, RFID tags, interactive packaging, and consumer products. The company also markets wearable temperature monitoring technologies, such as TempTraq, a Bluetooth-enabled patch that senses, records, and transmits body temperature data to mobile devices, and integrates with electronic health record systems for clinical monitoring. Founded in 2002 as Thin Battery Technologies and renamed Blue Spark Technologies in 2008, the company is headquartered in Westlake, Ohio.

Imalux Corporation, an Ohio medical device company, is positioned to become the worldwide leader in the commercializationPhoto of medical imaging equipment and devices based on its proprietary Optical Coherence Tomography (OCT) technology. The Company’s products provide real-time, high spatial resolution imaging at the point-of-care in a variety of medical applications. OCT is a new imaging modality for visualization of tissue microstructure, especially in anatomical areas with stratified tissue. It has the ability to detect near-surface tissue abnormalities indicative of disease, which established imaging modalities might not detect. Many diseases, including cancer, are associated with superficial tissue structure disruption. Today, there is no commercialized in vivo method to visualize this tissue structure alteration; clinicians must do a biopsy and an ex vivo histopathological review using a conventional microscope. Imalux OCT products can be used to visualize structural disruptions in vivo at the point of care.

Imalux Corporation, an Ohio medical device company, is positioned to become the worldwide leader in the commercializationPhoto of medical imaging equipment and devices based on its proprietary Optical Coherence Tomography (OCT) technology. The Company’s products provide real-time, high spatial resolution imaging at the point-of-care in a variety of medical applications. OCT is a new imaging modality for visualization of tissue microstructure, especially in anatomical areas with stratified tissue. It has the ability to detect near-surface tissue abnormalities indicative of disease, which established imaging modalities might not detect. Many diseases, including cancer, are associated with superficial tissue structure disruption. Today, there is no commercialized in vivo method to visualize this tissue structure alteration; clinicians must do a biopsy and an ex vivo histopathological review using a conventional microscope. Imalux OCT products can be used to visualize structural disruptions in vivo at the point of care.