Green Park & Golf Ventures

MicroTransponder, Inc. is a medical device company based in Austin, Texas, specializing in the development and commercialization of neurostimulation devices aimed at treating neurological disorders. Founded in 2007, the company focuses on therapies that utilize vagus nerve stimulation to address conditions such as tinnitus, chronic pain, and rehabilitation following strokes. Its flagship product, Vivistim, has received FDA approval for use in ischemic stroke survivors experiencing moderate to severe upper limb impairment. MicroTransponder's innovative approaches, which include paired vagus nerve stimulation and wireless neurostimulation systems, are designed to enhance recovery and improve quality of life for patients facing various neurological challenges.

Affineon is the AI inbox that saves provider time. We automatically handle normal and clinically insignificant lab results, and help providers get through abnormal lab results faster. Our AI automatically groups, analyzes, and trends lab results into a smart summary, including possible next steps and a complete patient note. We also route "noise" to staff, reducing the number of messages a physician needs to pay attention to by up to 30%. The result is 5+ hours saved per week per provider. Plus, Affineon tightly integrates with the EHR, so providers don’t need to change their existing workflow.

Prolocor is a biotechnology company founded in 2020 and based in Philadelphia, Pennsylvania, specializing in the development of diagnostic tests for cardiovascular diseases. The company focuses on creating a precise method to assess and manage the risk associated with these conditions. Prolocor's primary product quantifies platelet FcγRIIa to identify patients at varying levels of risk for heart attack, stroke, and cardiovascular death. Utilizing flow cytometry, the tests measure the number of FcγRIIa molecules per platelet, which assists healthcare providers in optimizing treatment strategies to minimize bleeding and reduce the likelihood of recurrent thrombotic events.

Worlds, Inc. specializes in spatial artificial intelligence solutions, offering its flagship platform, SpatialSense. This innovative platform integrates deep learning and Internet of Things (IoT) technology within a four-dimensional environment, allowing organizations to remotely observe and analyze their physical spaces. Key components of SpatialSense include WorldTrainer, which trains the AI to recognize people, objects, and events; WorldBuilder, which facilitates the importation and calibration of 3D models for detailed analysis; WorldNavigator, enabling virtual navigation between locations; and WorldAI, which helps clients create specialized AI applications and virtual entities. The company targets various sectors, including military, healthcare, and energy, to enhance operational insights and efficiency. Founded in 2018, Worlds, Inc. is headquartered in Dallas, Texas.

Validic, Inc. is a technology company specializing in a cloud-based platform that collects and manages mobile health data from various internet-enabled applications and devices. Founded in 2010 and based in Durham, North Carolina, Validic connects healthcare organizations with over 400 clinical and consumer devices, allowing for the integration of patient-recorded data into clinical workflows. Its primary offerings include Validic Solution, which links digital health data to healthcare providers; Validic Connect, which facilitates access to a broader range of clinical and consumer applications; and Validic Mobile, designed for data collection from health apps and in-home devices. The company serves a diverse clientele, including wellness companies, healthcare providers, pharmaceuticals, and health plans, with the goal of enhancing the quality of human life through actionable health data.

Prolocor is a biotechnology company founded in 2020 and based in Philadelphia, Pennsylvania, specializing in the development of diagnostic tests for cardiovascular diseases. The company focuses on creating a precise method to assess and manage the risk associated with these conditions. Prolocor's primary product quantifies platelet FcγRIIa to identify patients at varying levels of risk for heart attack, stroke, and cardiovascular death. Utilizing flow cytometry, the tests measure the number of FcγRIIa molecules per platelet, which assists healthcare providers in optimizing treatment strategies to minimize bleeding and reduce the likelihood of recurrent thrombotic events.

MicroTransponder, Inc. is a medical device company based in Austin, Texas, specializing in the development and commercialization of neurostimulation devices aimed at treating neurological disorders. Founded in 2007, the company focuses on therapies that utilize vagus nerve stimulation to address conditions such as tinnitus, chronic pain, and rehabilitation following strokes. Its flagship product, Vivistim, has received FDA approval for use in ischemic stroke survivors experiencing moderate to severe upper limb impairment. MicroTransponder's innovative approaches, which include paired vagus nerve stimulation and wireless neurostimulation systems, are designed to enhance recovery and improve quality of life for patients facing various neurological challenges.

Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.

Alto is a ridesharing service that provides on-demand transportation using a dedicated fleet of well-maintained vehicles. Each driver is an employee of the company, ensuring they are thoroughly vetted and trained to deliver a consistent and professional experience for riders. Alto's innovative app and in-car technology allow members to customize their rides, including options for music selection and climate control. The company, founded in 2018 and headquartered in Dallas, Texas, aims to offer safe and sanitized rides, making it easy for customers to book private transportation. Alto initially launched its services in Dallas and has plans to expand to additional cities across the United States.

Empirical Spine, Inc. is a medical device company based in San Carlos, California, that specializes in the development of a stabilization system for orthopedic and spinal surgery. The company's flagship product, LimiFlex, is a paraspinous tension band designed to stabilize the spine without compromising its function, specifically targeting patients with degenerative lumbar spinal disorders. This minimally invasive device is particularly beneficial for individuals suffering from spinal stenosis and grade I degenerative spondylolisthesis, providing healthcare providers with effective tools for secure spinal surgeries. Empirical Spine was incorporated in 2015 and continues to focus on innovative solutions in spinal care.

Avanta Risk Management offers financial management and consulting services. Data procurement, validation, and risk mitigation strategies exist within the financial services industry, ranging from nonexistent to more formal models. For inquiries, email, telephone numbers, and physical addresses are available on their website.

Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.

Noninvasix, Inc. is a medical technology company based in Galveston, Texas, that specializes in non-invasive precision oximetry for measuring brain oxygenation in preterm infants within neonatal intensive care units. Founded in 2007 by Dr. Donald Prough and Dr. Rinat Esenaliev at the University of Texas Medical Branch, the company has developed a novel optoacoustic platform technology that allows for continuous monitoring of oxygen sufficiency in organs and veins without the need for invasive procedures. This technology is particularly useful in diagnosing and managing conditions such as sepsis and septic shock, enabling clinicians to assess tissue hypoxia in real-time and adjust treatments accordingly. Noninvasix has received over $6.8 million in funding, including substantial grants from the NIH and DOD, and has been recognized in various prestigious accelerator programs. The company's innovations have been validated in multiple peer-reviewed studies, and its intellectual property includes numerous patents both in the U.S. and internationally.

NovaScan, Inc. is a company dedicated to the development and manufacturing of innovative cancer detection devices. Founded by the former Dean of the Engineering School at the University of Wisconsin Milwaukee, NovaScan specializes in a non-invasive detection platform that utilizes Cole relaxation frequency technology for the identification and stratification of various cancers. Its product line includes MarginScan for skin cancer detection, BiopsyScan for breast biopsy procedures, FastScan Probe for breast cancer identification, and additional technologies that facilitate electrical mammograms and the detection of multiple cancer types. The company, incorporated in 2001 and headquartered in Chicago, Illinois, focuses on improving patient outcomes and reducing healthcare costs through its rapid, accurate diagnostic solutions, which do not require extensive capital equipment or are limited by size. NovaScan's technologies are designed to enhance minimally invasive procedures and optimize therapeutic dosing within tumors, reflecting its commitment to advancing cancer care.

Worlds, Inc. specializes in spatial artificial intelligence solutions, offering its flagship platform, SpatialSense. This innovative platform integrates deep learning and Internet of Things (IoT) technology within a four-dimensional environment, allowing organizations to remotely observe and analyze their physical spaces. Key components of SpatialSense include WorldTrainer, which trains the AI to recognize people, objects, and events; WorldBuilder, which facilitates the importation and calibration of 3D models for detailed analysis; WorldNavigator, enabling virtual navigation between locations; and WorldAI, which helps clients create specialized AI applications and virtual entities. The company targets various sectors, including military, healthcare, and energy, to enhance operational insights and efficiency. Founded in 2018, Worlds, Inc. is headquartered in Dallas, Texas.

OneDay is a Texas-based software-as-a-service company that focuses on enhancing business growth and customer engagement through video storytelling technology. The company's online application provides tools for businesses to create customizable branded video content at scale. It includes question-and-answer prompts specifically designed for senior living communities, aiming to boost resident engagement and enhance customer satisfaction. By leveraging its platform, OneDay enables clients to utilize effective video marketing strategies, ultimately driving revenue growth and improving overall customer experiences.

Ataia Medical, founded in 2017 by biomedical engineers and critical care physicians, focuses on enhancing communication for hospital patients who are unable to speak due to the constraints of hard plastic masks. The company has developed an innovative medical device and communication system that serves as an intuitive aid, establishing channels for patients to connect verbally with their physicians, caregivers, and family members. This system is particularly beneficial for patients undergoing non-invasive ventilation and oxygen therapies in critical care settings, allowing them to express their needs and concerns effectively. Through these solutions, Ataia Medical aims to empower patients with the ability to communicate during critical moments of care.

Gregor Diagnostics Inc. is a molecular diagnostics company based in Madison, Wisconsin, founded in 2016. The company focuses on developing innovative screening tests for prostate cancer, utilizing seminal fluid as a sample source. Its technology aims to detect prostate cancer at early stages and differentiate between indolent and aggressive forms of the disease. This capability enables physicians to minimize overdiagnosis and overtreatment of less aggressive cancer while enhancing the detection and management of more aggressive cases. Gregor Diagnostics' approach represents a significant advancement in the field of prostate cancer diagnostics.

CounterFind Inc., based in Dallas, Texas, specializes in software that tracks and eliminates advertisements for counterfeit products in real-time. Founded in 2016, the company utilizes a proprietary filtering formula combined with advanced image recognition technology and industry expertise to identify and remove counterfeit merchandise listings on platforms like Facebook and Amazon. This turnkey solution assists brands in protecting their intellectual property by effectively detecting and shutting down infringing advertisements and product listings online.

Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that specializes in developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to disrupt the insulin and insulin delivery market with its first-in-class, ultra-rapid acting insulin, which is stabilized and highly concentrated. This new insulin formulation is designed for use in a disposable, postage-stamp-sized glucose management system and can also be utilized in existing insulin pumps. In addition to its lead program, Thermalin is exploring partnerships to develop no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. By creating insulin analogs that do not require refrigeration and are rapidly absorbed, Thermalin seeks to reduce the burden of insulin therapy, thereby improving patient adherence and health outcomes.

Take Command Health is a health insurance software provider that focuses on assisting small businesses and independent professionals in managing their health insurance needs. The company offers an innovative platform that allows small employers to reimburse employees tax-free for health insurance and medical expenses through a small business health reimbursement arrangement. By providing unbiased health plan recommendations and utilizing advanced plan choice software, Take Command Health empowers employers and employees to make informed decisions regarding health insurance. The company aims to simplify the health insurance process for small businesses while enhancing the overall experience for consumers.

Meta SaaS, Inc. develops a software as a service (SaaS) management solution tailored for small and medium-sized businesses. The platform offers a comprehensive vendor management system that consolidates various SaaS applications into a single dashboard, enabling users to track and manage their subscriptions effectively. It assists businesses in monitoring license utilization across all vendors, providing insights into actual usage and identifying potential savings. Additionally, the solution maintains PCI compliance and integrates with expense, accounting, and payment vendors, streamlining financial oversight. Meta SaaS also tracks contract dates and adjusts reminders based on contract values and vendor-specific requirements. Founded in 2016 and based in Austin, Texas, the company operates as a subsidiary of Flexera Software LLC.

Semler Scientific, Inc. is a medical technology company based in San Jose, California, focused on developing, manufacturing, and marketing proprietary products designed to assist healthcare providers in evaluating and treating chronic diseases. Founded in 2007, the company offers innovative solutions such as QuantaFlo, a quick in-office blood flow test that enables healthcare providers to assess patients' vascular conditions effectively. Semler's products cater to a diverse range of medical professionals, including cardiologists, nephrologists, and primary care physicians, as well as healthcare insurance plans and integrated delivery networks. The company aims to enhance the clinical effectiveness and efficiency of healthcare delivery while ensuring that providers can fully capture reimbursement for their services. With a commitment to advancing medical risk assessment, Semler Scientific is recognized for its contributions to improving patient care in the United States.

Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.

Simprica Spine is a stabilization system designed to stabilize the spine in flexion and helps patients rehabilitate better.

Orb Health, Inc. is a mobile healthcare technology company based in Richardson, Texas, founded in 2011. It specializes in providing innovative solutions that facilitate access to personalized healthcare services for physicians, employers, clinical laboratories, and patients. The company’s flagship offering, Collaborative Virtual Care, allows healthcare providers to deliver reimbursed Medicare services, including Chronic Care Management, as a virtual extension of their practice. This model eliminates the need for additional staff, applications, or office space, integrating seamlessly with existing electronic medical records (EMR) systems. By embedding best practices into its workflow, Orb Health empowers remote providers to deliver high-quality care while enhancing collaboration among healthcare teams. This approach not only improves patient access and outcomes but also increases reimbursements and overall profitability for various healthcare organizations, including Federally Qualified Health Centers and Accountable Care Organizations.

Archeio Technologies, LLC is a provider of cloud-based well information management software tailored for the oil and gas industry. The company's flagship product, SkyWell, enables exploration and production companies to secure, centralize, and tag well information, facilitating efficient data management for engineers, geologists, and landmen across various devices. In addition to its software solutions, Archeio offers comprehensive support services, including on-premise installation, end-user training, data preparation and migrations, technical integration, and ongoing customer support. Founded in 2014 and based in Dallas, Texas, Archeio Technologies operates as a subsidiary of Quorum Business Solutions, Inc. Its application suite enhances data collection and management processes, allowing companies to improve operational performance and make informed business decisions.

Potrero Medical, Inc. is a healthcare technology company focused on developing advanced monitoring devices that detect subtle changes in physiological parameters to enhance patient care in critical settings. Its innovative products provide early warnings for conditions such as sepsis and systemic inflammatory response syndrome, while also optimizing treatment by monitoring fluid levels during resuscitation. The company's devices measure various metrics, including intra-abdominal pressure, core body temperature, heart rate, respiratory rate, relative cardiac output, and urine output. Founded in 2011 and headquartered in Hayward, California, Potrero Medical aims to leverage smart sensors and artificial intelligence to create a predictive health platform that assists medical teams in anticipating adverse outcomes in critical care.

Take Command Health is a health insurance software provider that focuses on assisting small businesses and independent professionals in managing their health insurance needs. The company offers an innovative platform that allows small employers to reimburse employees tax-free for health insurance and medical expenses through a small business health reimbursement arrangement. By providing unbiased health plan recommendations and utilizing advanced plan choice software, Take Command Health empowers employers and employees to make informed decisions regarding health insurance. The company aims to simplify the health insurance process for small businesses while enhancing the overall experience for consumers.

Dignitana AB is a medical technology company that specializes in scalp cooling technology to assist cancer patients undergoing chemotherapy. The company has developed the DigniCap® Scalp Cooling System, a patented device designed to minimize chemotherapy-induced hair loss. Clinical studies have shown that the system is effective, with over 80% of treated patients able to retain enough hair to avoid the need for a wig. Dignitana's focus is on enhancing the well-being and quality of life of patients during their treatment journey, and it generates a significant portion of its revenue from the United States market.

TheraNova, LLC is a medical device development company based in Redwood City, California, founded in 2006 by Daniel R. Burnett. The company focuses on creating innovative biomedical device technologies, including low frequency induction therapy, cardiovascular anchors, dynamic vacuum compression systems, and auto-sterilizing implants. Additionally, TheraNova develops a range of other medical devices, such as non-invasive therapies for obesity and incontinence, an implantable shunt for chronic fluid management, therapeutic hypothermia solutions, and breast implants. Beyond product development, TheraNova also serves as an innovation incubator, assisting in clinical development and strategic investments for medical device startups, providing essential resources like research, regulatory support, and business development expertise.

Adient Medical Inc. is a company specializing in the development and delivery of implantable and absorbable medical devices, primarily focused on preventing pulmonary embolisms. Founded in 2012 and headquartered in Pearland, Texas, Adient Medical aims to create devices that are safe and effective throughout their intended use, and then naturally dissolve without the need for surgical removal. This innovative approach not only enhances patient safety but also reduces the potential for complications and the costs associated with removal procedures. Through its absorbable vascular filter, Adient Medical provides healthcare professionals with a safer alternative for managing the risk of pulmonary embolism in patients.

PuraCath Medical, Inc. is a San Francisco-based company that focuses on developing innovative devices for peritoneal dialysis (PD) disinfection. Founded in 2010, the company's primary aim is to enhance the quality of life for dialysis patients by reducing infections related to catheter connections. PuraCath's technology employs proprietary ultraviolet methods to disinfect PD catheters, thereby minimizing the risk of infectious complications. This approach not only safeguards patients' health but also simplifies the connection process, reducing the reliance on patient compliance. Through these advancements, PuraCath Medical strives to ensure that patients undergoing PD can experience a more efficient and safer treatment regimen.

Xclaim Mobile, Inc. is a company that specializes in developing an enterprise-grade mobile offer platform aimed at enhancing digital marketing efforts. Founded in 2016 and based in Dallas, Texas, Xclaim offers a platform that streamlines the transition to mobile marketing by integrating location-based technology. This software detects user devices, locations, and wallet types, allowing for customized offers compatible with major mobile payment systems such as Apple Pay, Android Pay, and Microsoft Wallet. By enabling marketers to deliver targeted content through mobile wallets, Xclaim helps brands engage consumers effectively based on time and location triggers. The platform serves various industries, including telecommunications, consumer lending, automotive, and retail, facilitating improved customer interaction and driving revenue through enhanced digital advertising strategies.

Savara is an orphan lung disease company. Savara’s pipeline comprises Molgradex, an inhaled granulocyte-macrophage colony-stimulating factor, or GM-CSF, in Phase 3 development for autoimmune pulmonary alveolar proteinosis, or aPAP, in Phase 2a development for nontuberculous mycobacteria, or NTM, lung infection, and in preparation for Phase 2a development in cystic fibrosis, or CF, affected individuals with chronic NTM lung infection; and AeroVanc, a Phase 3 stage inhaled vancomycin for treatment of persistent methicillin resistant staphylococcus aureus, or MRSA, lung infection in CF. Savara’s strategy involves expanding its pipeline of potentially best-in-class products through indication expansion, strategic development partnerships and product acquisitions, with the goal of becoming a leading company in its field. The most recent acquisition is aerosolized amikacin/fosfomycin, a Phase 2 ready, proprietary combination antibiotic, which has demonstrated potent and broad-spectrum antibacterial activity against highly drug resistant pathogens. Savara’s management team has significant experience in orphan drug development and pulmonary medicine, identifying unmet needs, developing and acquiring new product candidates, and effectively advancing them to approvals and commercialization.

MicroTransponder, Inc. is a medical device company based in Austin, Texas, specializing in the development and commercialization of neurostimulation devices aimed at treating neurological disorders. Founded in 2007, the company focuses on therapies that utilize vagus nerve stimulation to address conditions such as tinnitus, chronic pain, and rehabilitation following strokes. Its flagship product, Vivistim, has received FDA approval for use in ischemic stroke survivors experiencing moderate to severe upper limb impairment. MicroTransponder's innovative approaches, which include paired vagus nerve stimulation and wireless neurostimulation systems, are designed to enhance recovery and improve quality of life for patients facing various neurological challenges.

Supergoop, LLC is a skincare brand focused exclusively on sun protection, offering a diverse range of products designed to provide ultraviolet (UV) protection. Founded in 2007 and headquartered in San Antonio, Texas, the company’s product lineup includes sunscreen mousse, serum, CC cream, mineral setting powder, anti-aging eye cream, and lip balm for facial use, as well as hand cream, mineral sunscreen mist, and body butter for body care. The brand also caters to children with specialized lip balms and sunscreens. In addition, Supergoop manufactures mineral-based products and travel-friendly options. Its products are available for purchase online and in various retail stores.

CancerGene Connect is a developer of a cloud-based genetic assessment platform that focuses on collecting, assessing, and managing genetic family histories. The platform enhances genetic counseling programs by streamlining the collection of family medical histories and facilitating cancer risk assessments. This innovative approach allows clinicians to dedicate more time to addressing patient risks, as it significantly reduces the time spent on organizing data. By leveraging evolving technology, CancerGene Connect aims to create powerful connections between patients and healthcare providers, ultimately improving the overall effectiveness of cancer risk management.

Kickbox, Inc. is a Dallas-based company that specializes in email address verification services. Incorporated in 2015, it focuses on helping businesses ensure their emails reach real users by identifying and filtering out undeliverable, fake, and low-quality addresses. This service aims to enhance the sender's reputation, improve email open rates, and reduce costs associated with ineffective email marketing campaigns. As of August 2020, Kickbox operates as a subsidiary of J2 Global, Inc.

Dignitana AB is a medical technology company that specializes in scalp cooling technology to assist cancer patients undergoing chemotherapy. The company has developed the DigniCap® Scalp Cooling System, a patented device designed to minimize chemotherapy-induced hair loss. Clinical studies have shown that the system is effective, with over 80% of treated patients able to retain enough hair to avoid the need for a wig. Dignitana's focus is on enhancing the well-being and quality of life of patients during their treatment journey, and it generates a significant portion of its revenue from the United States market.

AlgoMedica, Inc. is a medical imaging software company specializing in solutions that significantly reduce radiation exposure during CT scans. The company has developed PixelShine, a software solution that operates on server or cloud platforms to enhance CT images captured at only 10% of the standard radiation dose. Utilizing advanced image enhancing and noise reduction technologies based on artificial neural networks, PixelShine improves the quality of these low-dose images, making them comparable to those taken under standard protocols. This technology is versatile and can be applied to various body parts, including the abdomen, pelvis, head, liver, and pediatric imaging. Established in 2012, AlgoMedica is headquartered in Palo Alto, California, and aims to provide medical facilities with advanced imaging capabilities while minimizing radiation exposure for patients.

TheraNova, LLC is a medical device development company based in Redwood City, California, founded in 2006 by Daniel R. Burnett. The company focuses on creating innovative biomedical device technologies, including low frequency induction therapy, cardiovascular anchors, dynamic vacuum compression systems, and auto-sterilizing implants. Additionally, TheraNova develops a range of other medical devices, such as non-invasive therapies for obesity and incontinence, an implantable shunt for chronic fluid management, therapeutic hypothermia solutions, and breast implants. Beyond product development, TheraNova also serves as an innovation incubator, assisting in clinical development and strategic investments for medical device startups, providing essential resources like research, regulatory support, and business development expertise.

Admittance Technologies, Inc. is a medical technology company based in Austin, Texas, with an additional office in San Antonio. Founded in 2010, the company specializes in developing innovative software and platform technology aimed at improving the quality of life for heart failure patients. Its flagship product, CardioVol, utilizes electric fields to interrogate the heart, allowing for real-time differentiation between blood and heart muscle components. This technology enables the monitoring of critical hemodynamic data, such as left ventricular end-diastolic volume and stroke volume, without the need for additional implants. By optimizing pacemaker settings and providing alerts for potential heart failure, Admittance Technologies aims to enhance patient outcomes and support healthcare providers in managing heart disease more effectively.

Validic, Inc. is a technology company specializing in a cloud-based platform that collects and manages mobile health data from various internet-enabled applications and devices. Founded in 2010 and based in Durham, North Carolina, Validic connects healthcare organizations with over 400 clinical and consumer devices, allowing for the integration of patient-recorded data into clinical workflows. Its primary offerings include Validic Solution, which links digital health data to healthcare providers; Validic Connect, which facilitates access to a broader range of clinical and consumer applications; and Validic Mobile, designed for data collection from health apps and in-home devices. The company serves a diverse clientele, including wellness companies, healthcare providers, pharmaceuticals, and health plans, with the goal of enhancing the quality of human life through actionable health data.

InterVene, Inc. is a medical device company based in South San Francisco, California, that specializes in innovative catheter-based therapies for chronic venous insufficiency (CVI), particularly addressing deep vein valve failure. Established in 2011, InterVene has developed the BlueLeaf™ Endovenous Valve Formation System, a non-implantable solution aimed at treating severe venous conditions. The company's devices enable healthcare professionals to create new vein valves from the patient's own vein wall tissue, improving blood flow from the legs back to the heart. By focusing on minimally invasive treatments, InterVene seeks to enhance patient outcomes for those suffering from venous stasis ulcers and associated symptoms.

Orb Health, Inc. is a mobile healthcare technology company based in Richardson, Texas, founded in 2011. It specializes in providing innovative solutions that facilitate access to personalized healthcare services for physicians, employers, clinical laboratories, and patients. The company’s flagship offering, Collaborative Virtual Care, allows healthcare providers to deliver reimbursed Medicare services, including Chronic Care Management, as a virtual extension of their practice. This model eliminates the need for additional staff, applications, or office space, integrating seamlessly with existing electronic medical records (EMR) systems. By embedding best practices into its workflow, Orb Health empowers remote providers to deliver high-quality care while enhancing collaboration among healthcare teams. This approach not only improves patient access and outcomes but also increases reimbursements and overall profitability for various healthcare organizations, including Federally Qualified Health Centers and Accountable Care Organizations.

Vapogenix, Inc. is a clinical-stage company based in Houston, Texas, focused on developing non-narcotic analgesics aimed at treating localized pain. Founded in 2006, the company specializes in formulating volatile anesthetics to alleviate discomfort associated with procedures such as venipuncture, venous cannulation, and minor dermatological interventions. Vapogenix's products are designed to provide effective pain relief at the source, particularly for hospitalized children undergoing venous access procedures. By utilizing these innovative analgesics, Vapogenix aims to enhance patient comfort, reduce procedural anxiety, and improve the efficiency of healthcare providers.

Lantern Pharma Inc. is a clinical stage biotechnology company based in Dallas, Texas, specializing in precision oncology therapeutics. The company employs artificial intelligence and machine learning to develop innovative cancer treatments and to revitalize abandoned drug candidates. Its lead drug candidate, LP-100, is currently undergoing phase II clinical trials for metastatic, castration-resistant prostate cancer. Additionally, Lantern is developing LP-300 as a combination therapy for female non-smokers diagnosed with non-small cell lung cancer adenocarcinoma. The firm is also advancing LP-184, a preclinical drug candidate designed to target cancer cells that overexpress specific biomarkers. Lantern Pharma utilizes its proprietary RADR platform to address challenges in oncology drug development, such as patient stratification and understanding mechanisms of action, thereby aiming to accelerate the development of personalized cancer therapies.

Retrotope Inc. is a pharmaceutical company focused on developing therapeutics for degenerative diseases, particularly those affecting mitochondrial health. Founded in 2006 and based in Los Altos, California, Retrotope specializes in addressing conditions such as Parkinson's disease, Alzheimer's disease, mitochondrial myopathies, and retinopathies. The company is known for its drug RT001, which targets infantile neuroaxonal dystrophy, and it employs a unique drug platform that utilizes isotope effects to mitigate oxidative stress and cellular damage. Through several discovery and development programs, Retrotope aims to create innovative solutions for a range of neurological disorders, including Friedreich's ataxia, while also contributing to the broader understanding of metabolic processes related to these conditions.

Ikonopedia, LLC specializes in developing a cloud-based breast study interpretation and reporting system aimed at enhancing the workflows of radiologists. Established in 2012 and headquartered in Dallas, Texas, the company provides a comprehensive Mammography Reporting System that generates structured, MQSA-compliant reports tailored to individual radiologists, as well as SonoPro, a web application designed to assist radiologists during diagnostic breast ultrasound exams. Ikonopedia's solutions are utilized in telemammography and satellite clinics, featuring capabilities such as automated patient tracking and monitoring to ensure comprehensive care. The system supports patient letters and questionnaires in multiple languages and is designed to be compatible with modern devices. By prioritizing clear and consistent clinical reporting, Ikonopedia aims to enhance patient safety, reduce errors, and ensure compliance with industry standards, ultimately contributing to improved health outcomes for women.

Silicone Arts Laboratories, LLC, founded in 2010 and based in Memphis, Tennessee, specializes in manufacturing cosmetic products designed to enhance physical appearances. The company is best known for Dermaflage, a topical scar filler that effectively conceals recessed scars and skin defects on both the face and body without the need for surgical procedures or injections. Dermaflage uses silicone to mimic the tone and texture of the user's skin, providing an immediate solution for hiding various types of scars, including those resulting from acne, chickenpox, bite marks, cancer, and surgeries. Additionally, Silicone Arts Laboratories develops AeXP (Anatomical Eye – Experimental), a precise replica of a human eye intended for medical training and device testing.

Socrates Health Solutions, Inc. is a Dallas-based company that develops and manufactures innovative diabetes testing devices. The company offers a non-invasive self-monitoring device for blood glucose that eliminates the need for needle insertions and finger pricks. This device provides real-time glucose readings, generates custom alerts for critical blood sugar levels, and enables users to track their glucose data through mobile devices, facilitating better diabetes management. By delivering accurate and pain-free monitoring options, Socrates Health Solutions aims to improve access to affordable healthcare and enhance the quality of life for individuals managing diabetes. The company was incorporated in 2013 and continues to engage in activities to expand its impact in the healthcare sector.

e-Nicotine Technology, Inc. is a healthcare company based in Draper, Utah, focused on creating electronic nicotine delivery products designed to assist smokers in transitioning away from traditional cigarettes. Founded in 2012, the company aims to provide a safer alternative by delivering precise doses of nicotine through aerosolized particles that promote deep lung absorption. This innovative approach helps individuals manage their cravings while avoiding the harmful effects of cigarette smoke and secondhand vapor. e-Nicotine Technology is developing its nicotine delivery devices under a regulatory framework established by the FDA's Center for Tobacco Products, which facilitates a streamlined path to market. The company's founders possess extensive experience in entrepreneurship, capital acquisition, and product development, while the management team brings expertise in aerosol technology, addiction science, and mobile health applications.

AdBm Technologies is an acoustical engineering firm based in Austin, Texas, established in 2012. The company specializes in creating innovative noise abatement solutions tailored for marine environments. By utilizing large arrays of Helmholtz resonators tuned to specific frequencies, AdBm Technologies effectively captures and mitigates noise generated by various industrial operations at sea. This technology aims to safeguard marine wildlife from the harmful impacts of underwater noise pollution, positioning the company at the intersection of environmental engineering, marine technology, and mechanical engineering.

Channel Medsystems, Inc. is a medical device company focused on women's healthcare, specifically in the area of endometrial ablation. Founded in 2009 and based in Emeryville, California, the company specializes in developing cryothermic technology that integrates cryothermic energy into a user-friendly, handheld device. This innovative delivery system allows for effective endometrial cryoablation without the need for separate control units or extensive capital equipment, making it more accessible for patients and healthcare providers. Channel Medsystems aims to empower women to take control of their health by providing cutting-edge solutions that enhance their healthcare experience.

Nasseo, Inc. is a medical device company based in Peoria, Arizona, specializing in the development and manufacture of dental and orthopedic implant systems. Established in 2012, the company has pioneered next-generation nanotube implant surface technology, known as TiArray, which modifies the natural oxide layer of implant materials to create a uniform nanotube array. This innovative technology has demonstrated benefits such as stronger bonding, faster healing, and improved soft tissue responses, particularly beneficial for patients with circulatory issues, including diabetics and smokers. Nasseo's flagship product, the TiArray Dental Implant, has received FDA approval, and the company plans to initiate post-market clinical trials. Additionally, Nasseo is working on a Titanium-PEEK hybrid interbody fusion device that incorporates the TiArray technology, further enhancing treatment options for healthcare professionals and their patients worldwide.

Validic, Inc. is a technology company specializing in a cloud-based platform that collects and manages mobile health data from various internet-enabled applications and devices. Founded in 2010 and based in Durham, North Carolina, Validic connects healthcare organizations with over 400 clinical and consumer devices, allowing for the integration of patient-recorded data into clinical workflows. Its primary offerings include Validic Solution, which links digital health data to healthcare providers; Validic Connect, which facilitates access to a broader range of clinical and consumer applications; and Validic Mobile, designed for data collection from health apps and in-home devices. The company serves a diverse clientele, including wellness companies, healthcare providers, pharmaceuticals, and health plans, with the goal of enhancing the quality of human life through actionable health data.

Savara is an orphan lung disease company. Savara’s pipeline comprises Molgradex, an inhaled granulocyte-macrophage colony-stimulating factor, or GM-CSF, in Phase 3 development for autoimmune pulmonary alveolar proteinosis, or aPAP, in Phase 2a development for nontuberculous mycobacteria, or NTM, lung infection, and in preparation for Phase 2a development in cystic fibrosis, or CF, affected individuals with chronic NTM lung infection; and AeroVanc, a Phase 3 stage inhaled vancomycin for treatment of persistent methicillin resistant staphylococcus aureus, or MRSA, lung infection in CF. Savara’s strategy involves expanding its pipeline of potentially best-in-class products through indication expansion, strategic development partnerships and product acquisitions, with the goal of becoming a leading company in its field. The most recent acquisition is aerosolized amikacin/fosfomycin, a Phase 2 ready, proprietary combination antibiotic, which has demonstrated potent and broad-spectrum antibacterial activity against highly drug resistant pathogens. Savara’s management team has significant experience in orphan drug development and pulmonary medicine, identifying unmet needs, developing and acquiring new product candidates, and effectively advancing them to approvals and commercialization.

Cariloop, Inc. offers a digital platform designed to assist seniors and their families in navigating geriatric care options. The platform connects users with a variety of services, including assisted living facilities, Alzheimer care, adult daycare, hospice care, skilled nursing facilities, and home health care. It enables care providers to showcase their services through real-time updates, multimedia content, and analytics on user engagement. Additionally, Cariloop provides a team of experienced Care Coaches who offer personalized guidance to families throughout their caregiving journey. By combining these resources, Cariloop aims to alleviate caregiver stress, enhance collaboration among care teams, and facilitate better care management for seniors. Founded in 2012 and headquartered in Dallas, Texas, Cariloop serves as a comprehensive support system for families facing the complexities of elder care.

Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.

ImageVision specializes in providing advanced image and video recognition solutions for social media and multimedia platforms. By utilizing artificial intelligence and machine learning, the company automates the recognition and monetization of visual content, thereby enhancing revenue opportunities and safeguarding brand integrity for its clients. Their real-time visual recognition technology is employed by major industry players to facilitate image search, brand analytics, and ad customization, while also effectively managing objectionable content. ImageVision's platform includes features for automated filtering, motion recognition, and facial biometrics, enabling clients to operate more efficiently and reduce risks associated with content management.

Tractus Corporation specializes in developing innovative hardware and software technology for cancer detection in women, focusing on whole breast ultrasound systems. Founded in 2012 and based in Austin, Texas, the company addresses a significant need in the healthcare market for an affordable platform that enhances breast cancer screening. Its primary device, the BreastMapper, features a unique accessory probe that attaches to standard ultrasound systems and works in conjunction with proprietary software for analyzing and reporting ultrasound scans. This combined approach aims to improve the detection rates of small, treatable breast cancers, particularly in women with dense breast tissue, thereby serving as a valuable adjunct to traditional mammography.

Make My Plate is changing the dieting world! They present a visually appealing and fun approach to maintaining a healthy lifestyle. They are connecting the dietary ecosystem, answering the user's nutritional needs on one hand and creating a marketplace for professionals on the other.

Vapogenix, Inc. is a clinical-stage company based in Houston, Texas, focused on developing non-narcotic analgesics aimed at treating localized pain. Founded in 2006, the company specializes in formulating volatile anesthetics to alleviate discomfort associated with procedures such as venipuncture, venous cannulation, and minor dermatological interventions. Vapogenix's products are designed to provide effective pain relief at the source, particularly for hospitalized children undergoing venous access procedures. By utilizing these innovative analgesics, Vapogenix aims to enhance patient comfort, reduce procedural anxiety, and improve the efficiency of healthcare providers.

Socrates Health Solutions, Inc. is a Dallas-based company that develops and manufactures innovative diabetes testing devices. The company offers a non-invasive self-monitoring device for blood glucose that eliminates the need for needle insertions and finger pricks. This device provides real-time glucose readings, generates custom alerts for critical blood sugar levels, and enables users to track their glucose data through mobile devices, facilitating better diabetes management. By delivering accurate and pain-free monitoring options, Socrates Health Solutions aims to improve access to affordable healthcare and enhance the quality of life for individuals managing diabetes. The company was incorporated in 2013 and continues to engage in activities to expand its impact in the healthcare sector.

Tractus Corporation specializes in developing innovative hardware and software technology for cancer detection in women, focusing on whole breast ultrasound systems. Founded in 2012 and based in Austin, Texas, the company addresses a significant need in the healthcare market for an affordable platform that enhances breast cancer screening. Its primary device, the BreastMapper, features a unique accessory probe that attaches to standard ultrasound systems and works in conjunction with proprietary software for analyzing and reporting ultrasound scans. This combined approach aims to improve the detection rates of small, treatable breast cancers, particularly in women with dense breast tissue, thereby serving as a valuable adjunct to traditional mammography.

Maui Imaging, Inc., established in 2006 and located in Sunnyvale, California, specializes in the manufacture of advanced ultrasound imaging devices. The company offers innovative technology that enables imaging through and around various materials, including bones, metals, plastics, gas, and soft tissue. Utilizing techniques such as Computed Echo Tomography and adaptive beam forming, Maui Imaging's systems capture 3D images that traditional ultrasound methods cannot achieve. This capability enhances diagnostic and treatment options within the healthcare industry, providing valuable insights for medical professionals.

Brainspace Corporation specializes in eDiscovery software, information governance, and compliance solutions, primarily serving legal professionals, law firms, and litigation service providers. The company offers a range of products, including the Brainspace platform, which enhances the discovery, collection, and sharing of information while facilitating intelligent features for developers. Its flagship product, Brainspace Discovery, provides advanced unstructured data analytics, visual analytics, and intelligent search capabilities, tailored for complex data challenges in investigations and compliance. Founded in 2005 and headquartered in Addison, Texas, Brainspace has established itself as a leader in text analytics, helping enterprise clients derive insights and recognize connections in unstructured data. The company serves a diverse clientele, including Fortune 500 companies, consulting firms, and government agencies. In 2014, it rebranded from PureDiscovery Corporation and is currently a subsidiary of Colorado Buyer Inc.

e-Nicotine Technology, Inc. is a healthcare company based in Draper, Utah, focused on creating electronic nicotine delivery products designed to assist smokers in transitioning away from traditional cigarettes. Founded in 2012, the company aims to provide a safer alternative by delivering precise doses of nicotine through aerosolized particles that promote deep lung absorption. This innovative approach helps individuals manage their cravings while avoiding the harmful effects of cigarette smoke and secondhand vapor. e-Nicotine Technology is developing its nicotine delivery devices under a regulatory framework established by the FDA's Center for Tobacco Products, which facilitates a streamlined path to market. The company's founders possess extensive experience in entrepreneurship, capital acquisition, and product development, while the management team brings expertise in aerosol technology, addiction science, and mobile health applications.

MicroTransponder, Inc. is a medical device company based in Austin, Texas, specializing in the development and commercialization of neurostimulation devices aimed at treating neurological disorders. Founded in 2007, the company focuses on therapies that utilize vagus nerve stimulation to address conditions such as tinnitus, chronic pain, and rehabilitation following strokes. Its flagship product, Vivistim, has received FDA approval for use in ischemic stroke survivors experiencing moderate to severe upper limb impairment. MicroTransponder's innovative approaches, which include paired vagus nerve stimulation and wireless neurostimulation systems, are designed to enhance recovery and improve quality of life for patients facing various neurological challenges.

Supergoop, LLC is a skincare brand focused exclusively on sun protection, offering a diverse range of products designed to provide ultraviolet (UV) protection. Founded in 2007 and headquartered in San Antonio, Texas, the company’s product lineup includes sunscreen mousse, serum, CC cream, mineral setting powder, anti-aging eye cream, and lip balm for facial use, as well as hand cream, mineral sunscreen mist, and body butter for body care. The brand also caters to children with specialized lip balms and sunscreens. In addition, Supergoop manufactures mineral-based products and travel-friendly options. Its products are available for purchase online and in various retail stores.

Natural Dental Implants AG, founded in 2006 and based in Berlin, Germany, specializes in manufacturing non-surgical tooth replacement systems. The company focuses on providing innovative solutions for tooth replacement without the need for invasive procedures. In a similar vein, Replicate Dental Technologies, established in 2009 and headquartered in Dublin, Ireland, is committed to developing minimally-invasive dental solutions. Their patented product aims to change single tooth replacement by offering a patient-friendly alternative that avoids the drilling or damaging of healthy teeth. Both companies are dedicated to advancing dental care through their unique approaches to tooth replacement.

Ikonopedia, LLC specializes in developing a cloud-based breast study interpretation and reporting system aimed at enhancing the workflows of radiologists. Established in 2012 and headquartered in Dallas, Texas, the company provides a comprehensive Mammography Reporting System that generates structured, MQSA-compliant reports tailored to individual radiologists, as well as SonoPro, a web application designed to assist radiologists during diagnostic breast ultrasound exams. Ikonopedia's solutions are utilized in telemammography and satellite clinics, featuring capabilities such as automated patient tracking and monitoring to ensure comprehensive care. The system supports patient letters and questionnaires in multiple languages and is designed to be compatible with modern devices. By prioritizing clear and consistent clinical reporting, Ikonopedia aims to enhance patient safety, reduce errors, and ensure compliance with industry standards, ultimately contributing to improved health outcomes for women.

SendInc offers a secure email service designed for small to medium-sized businesses, professionals, non-profit organizations, and individuals. The company provides a SaaS-based electronic messaging and collaboration platform that integrates secure email functionalities into various web and software applications. By utilizing advanced email encryption methodologies, SendInc ensures that users can send messages while complying with important regulations such as HIPAA, GLBA, SOX, and PCI-DSS. This focus on security and compliance allows organizations to protect sensitive information and maintain the highest standards of data privacy.

MicroTransponder, Inc. is a medical device company based in Austin, Texas, specializing in the development and commercialization of neurostimulation devices aimed at treating neurological disorders. Founded in 2007, the company focuses on therapies that utilize vagus nerve stimulation to address conditions such as tinnitus, chronic pain, and rehabilitation following strokes. Its flagship product, Vivistim, has received FDA approval for use in ischemic stroke survivors experiencing moderate to severe upper limb impairment. MicroTransponder's innovative approaches, which include paired vagus nerve stimulation and wireless neurostimulation systems, are designed to enhance recovery and improve quality of life for patients facing various neurological challenges.

Tractus Corporation specializes in developing innovative hardware and software technology for cancer detection in women, focusing on whole breast ultrasound systems. Founded in 2012 and based in Austin, Texas, the company addresses a significant need in the healthcare market for an affordable platform that enhances breast cancer screening. Its primary device, the BreastMapper, features a unique accessory probe that attaches to standard ultrasound systems and works in conjunction with proprietary software for analyzing and reporting ultrasound scans. This combined approach aims to improve the detection rates of small, treatable breast cancers, particularly in women with dense breast tissue, thereby serving as a valuable adjunct to traditional mammography.

Perio Sciences, LLC is a Dallas-based company that specializes in the development of oral healthcare products. Founded in 2008, the company provides a range of offerings including dental gels, mouth rinses, toothpastes, and comprehensive oral care systems. Perio Sciences distributes its products through various channels, including dental professionals, hygienists, specialists, other medical practitioners, medi-spas, and online platforms.

TangoTab, Inc. operates a mobile application that connects consumers with restaurants while addressing local hunger in the United States. The app allows users to find nearby restaurants and access exclusive deals by checking in or redeeming offers at participating locations. Each time a deal is utilized, TangoTab donates the cost of a meal to a local food bank, effectively feeding individuals in need. This initiative not only benefits consumers with free restaurant deals but also serves as a yield-management tool for restaurants, helping them increase traffic during slower periods. Incorporated in 2010 and based in Dallas, Texas, TangoTab fosters a community-oriented approach where both consumers and restaurants contribute to combating hunger in their local areas.

Order Mapper Inc. is a Platform as a Service ("PaaS") startup founded in 2009. We make it easy for people to order virtually any physical good or service from almost any business from a mobile device such as a smartphone or tablet. Our cloud-based platform receives, processes, and delivers orders to businesses, providing targeted marketing and promotional opportunities. Our app 'Order Pizza' for iPhone is the largest independent pizza directory on mobile. We’ve fulfilled orders for over 30% of pizzerias in the United States, gaining over 250,000 downloads in the process and placing as one of the Top 100 Lifestyle apps in the App Store. We secured early investment from 500 Startups (Dave McClure) and were recently accepted into Tech Wildcatters (class of Spring 2012), one of the Top 10 business accelerators in the United States. We've been featured on TechCrunch, MacWorld, VentureBeat and Geekwire.

MobileLutions, LLC is a software solutions provider focused on preventing driving accidents and minimizing corporate liability associated with distracted driving. Founded in 2010 and based in Dallas, Texas, the company offers a mobile application called MobiLoc, designed to disable texting and other smartphone functionalities while a vehicle is in motion. MobiLoc is available in two versions: a free version that blocks texting when the vehicle exceeds 7 mph for 20 seconds, restoring access after a stop, and a paid version that additionally restricts email, social media, and web browsing. The paid version also includes a feature that allows passengers to unlock the phone for a limited time. MobileLutions aims to address the significant safety issue of distracted driving, as a substantial percentage of traffic accidents are linked to mobile phone use while driving.

Semler Scientific, Inc. is a medical technology company based in San Jose, California, focused on developing, manufacturing, and marketing proprietary products designed to assist healthcare providers in evaluating and treating chronic diseases. Founded in 2007, the company offers innovative solutions such as QuantaFlo, a quick in-office blood flow test that enables healthcare providers to assess patients' vascular conditions effectively. Semler's products cater to a diverse range of medical professionals, including cardiologists, nephrologists, and primary care physicians, as well as healthcare insurance plans and integrated delivery networks. The company aims to enhance the clinical effectiveness and efficiency of healthcare delivery while ensuring that providers can fully capture reimbursement for their services. With a commitment to advancing medical risk assessment, Semler Scientific is recognized for its contributions to improving patient care in the United States.

Demand Response programs are becoming an integral component of the evolving smart grid infrastructure. Large commercial building owners and operators are beginning to realize new sources of revenue available for their willingness to shed energy load during periods of peak consumption. Tenant comfort remains a primary concern for owners and operators; however, EdgePoint minimizes those concerns by providing a robust solution that ensures compliance with demand response events while maintaining comfort levels.

Savara is an orphan lung disease company. Savara’s pipeline comprises Molgradex, an inhaled granulocyte-macrophage colony-stimulating factor, or GM-CSF, in Phase 3 development for autoimmune pulmonary alveolar proteinosis, or aPAP, in Phase 2a development for nontuberculous mycobacteria, or NTM, lung infection, and in preparation for Phase 2a development in cystic fibrosis, or CF, affected individuals with chronic NTM lung infection; and AeroVanc, a Phase 3 stage inhaled vancomycin for treatment of persistent methicillin resistant staphylococcus aureus, or MRSA, lung infection in CF. Savara’s strategy involves expanding its pipeline of potentially best-in-class products through indication expansion, strategic development partnerships and product acquisitions, with the goal of becoming a leading company in its field. The most recent acquisition is aerosolized amikacin/fosfomycin, a Phase 2 ready, proprietary combination antibiotic, which has demonstrated potent and broad-spectrum antibacterial activity against highly drug resistant pathogens. Savara’s management team has significant experience in orphan drug development and pulmonary medicine, identifying unmet needs, developing and acquiring new product candidates, and effectively advancing them to approvals and commercialization.

MicroTransponder, Inc. is a medical device company based in Austin, Texas, specializing in the development and commercialization of neurostimulation devices aimed at treating neurological disorders. Founded in 2007, the company focuses on therapies that utilize vagus nerve stimulation to address conditions such as tinnitus, chronic pain, and rehabilitation following strokes. Its flagship product, Vivistim, has received FDA approval for use in ischemic stroke survivors experiencing moderate to severe upper limb impairment. MicroTransponder's innovative approaches, which include paired vagus nerve stimulation and wireless neurostimulation systems, are designed to enhance recovery and improve quality of life for patients facing various neurological challenges.

Natural Dental Implants AG, founded in 2006 and based in Berlin, Germany, specializes in manufacturing non-surgical tooth replacement systems. The company focuses on providing innovative solutions for tooth replacement without the need for invasive procedures. In a similar vein, Replicate Dental Technologies, established in 2009 and headquartered in Dublin, Ireland, is committed to developing minimally-invasive dental solutions. Their patented product aims to change single tooth replacement by offering a patient-friendly alternative that avoids the drilling or damaging of healthy teeth. Both companies are dedicated to advancing dental care through their unique approaches to tooth replacement.

SendInc offers a secure email service designed for small to medium-sized businesses, professionals, non-profit organizations, and individuals. The company provides a SaaS-based electronic messaging and collaboration platform that integrates secure email functionalities into various web and software applications. By utilizing advanced email encryption methodologies, SendInc ensures that users can send messages while complying with important regulations such as HIPAA, GLBA, SOX, and PCI-DSS. This focus on security and compliance allows organizations to protect sensitive information and maintain the highest standards of data privacy.

Serene Medical Inc. is a medical device company headquartered in San Ramon, California, specializing in neurotoxin-free treatments for motor nerve disorders. Founded in 2010, the company has developed the NeuBelle system, which utilizes radio frequency technology to precisely locate and interrupt motor nerve signals that control facial expressions, including frown lines. This minimally invasive approach offers longer-lasting results compared to traditional solutions, while also eliminating the need for neurotoxin injections. The technology not only benefits patients by providing a safer and more effective alternative but also offers physicians the opportunity to enhance their practice by attracting new patients and generating additional revenue. Serene Medical's innovative platform addresses significant aesthetic and therapeutic markets, positioning the company as a leader in the field of nerve ablation.

Hie Electronics, Inc. is a Texas-based company that specializes in the development and implementation of dense Blu-ray multi-tiered optical data storage units and enterprise-class digital video recorders. Its flagship product, the TeraStack Solution, provides robust data backup and disaster recovery capabilities, as well as storage solutions for video surveillance, medical data retention, and various enterprise applications. The TeraStack Solution supports online enterprise application hosting and nearline data storage, scalable to petabytes, while also offering unlimited offline data optical storage. Hie Electronics serves a diverse range of industries, including medical, law enforcement, and video surveillance, enabling effective and affordable management of digital assets and data storage needs. Established in 2004, the company has positioned itself as a provider of innovative solutions for critical data backup, archiving, and cyber forensics.

DxUpClose, Inc. is a company focused on developing a point-of-care bacterial diagnostic device that performs antibiotic sensitivity tests within sixty minutes. This innovative product can identify specific bacteria and assess their sensitivity to antibiotics, regardless of whether the targeted bacteria are present in the sample. At the conclusion of the test, the device securely transmits a list of effective antibiotics to the healthcare worker's email or smartphone, allowing for prompt interpretation and treatment decisions by physicians. This capability significantly reduces the time taken for optimal patient care, which typically ranges from one to three days. Designed to be lightweight, portable, and capable of operating in extreme temperatures, the device ensures reliable diagnostics while remaining easy to transport.

Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.