Innovation Works

Revitalize Energy is a consumer-focused company that specializes in eye drops aimed at alleviating fatigue caused by prolonged screen use. The product features a patented blend of stimulants and amino acids that provides immediate energy and relief from digital eye strain. With just 1-2 drops in each eye, users experience a refreshing effect that helps combat tiredness and enhances comfort, making it an ideal solution for those frequently engaged with digital devices.

Plexision develops cellular biomarkers for personalized diagnosis and drug development in solid organ transplantation, and immunological disorders. Plexision's first patented product, the PleximmuneTM assay, predicts the risk of transplant rejection. The test is based on patent-pending technology to measure antigen-specific white blood cells. Testing services for transplant recipients and drug developers are provided at Plexision’s CLIA-certified, central laboratory in Pittsburgh. Plexision currently offers cell-based testing for personalized assessment of rejection risk after solid organ transplantation The Pleximmune blood test is the first such test offered for children with liver or intestine transplantation.

SignatureDx is a biotechnology company that develops and operates a bioanalytical platform. This platform is designed to detect and monitor complex human diseases in their early, silent stages. The company focuses on non-invasive diagnostic testing, aiming to predict and treat diseases before they cause significant organ damage. By specializing in novel methods, SignatureDx enables individuals to receive timely and successful treatment, thereby improving health outcomes.

Ilant Health specializes in obesity management and cardiometabolic healthcare services. The company focuses on delivering treatment for obesity and weight management, utilizing advanced analytics powered by unstructured machine learning. This technology generates significant insights that aim to lower overall healthcare costs and enhance return on investment for obesity treatments. By offering effective solutions for weight loss, Ilant Health enables clients to achieve better health outcomes while simultaneously reducing expenses and accessing health plans through value-based care.

D.Sole specializes in the development of advanced foot insoles aimed at improving remote patient monitoring in podiatry, specifically for diabetic patients. These innovative, AI-powered insoles utilize multimodal sensors to detect early signs of complications, such as ulcers and nerve damage. By providing comprehensive physiological data, D.Sole enables clinicians to gain evidence-based insights for more effective foot treatments. The company's solution is notably more cost-effective than existing market options, detecting multiple foot complications compared to competitors that typically identify only one. This technology has the potential to significantly reduce healthcare costs, potentially saving hospitals over $100 million annually by decreasing readmission rates for foot complications, while private insurers could save more than $1 billion by minimizing expenses related to amputations and wound care.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

Ariel Precision Medicine is an integrated genomics and digital health company based in Pittsburgh, Pennsylvania, that focuses on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases. Founded in 2013, the company develops innovative clinical decision support tools designed to simplify personalized treatment, particularly through its flagship product, ArielDx. This cloud-based platform specifically aids in the diagnosis and management of pancreatic disease, enhancing the capabilities of healthcare providers in both emergency and clinical settings. Ariel Precision Medicine aims to improve patient outcomes by leveraging advanced technology and genomic insights in healthcare.

Revitalize Energy is a consumer-focused company that specializes in eye drops aimed at alleviating fatigue caused by prolonged screen use. The product features a patented blend of stimulants and amino acids that provides immediate energy and relief from digital eye strain. With just 1-2 drops in each eye, users experience a refreshing effect that helps combat tiredness and enhances comfort, making it an ideal solution for those frequently engaged with digital devices.

InnSight Technology is a biotechnology company focused on enhancing diagnostics and evaluation of eye diseases. The company develops innovative ophthalmic devices, including a novel hand-held biosensor designed for the detection of anterior ophthalmic injuries. Additionally, InnSight Technology works on advanced nanotechnology-based medical devices aimed at addressing specific clinical needs in ophthalmology. By providing these tools, the company seeks to improve ocular care for clinicians and their patients.

Gus Gear specializes in the development and manufacturing of wearable securement clothing designed to protect implanted medical devices. The company's flagship product, the Central Line Vest, effectively prevents damage, breakage, and accidental removal of central catheters. By providing securement solutions for various medical devices, including ostomy pouches and feeding tubes, Gus Gear aims to enhance patient outcomes and quality of life. Their innovative approach enables patients to maintain a higher level of independence and well-being while undergoing medical treatment, allowing them to live their lives to the fullest despite any health challenges.

MindTrace is a medical software company focused on enhancing neurosurgical procedures through the development of personalized 3D brain maps. By integrating advanced brain imaging with machine learning algorithms, the company creates simulations of surgical resection plans that allow neurosurgeons to predict patients' cognitive outcomes prior to surgery. This innovative approach enables surgeons to optimize the removal of brain tumors while minimizing damage to surrounding healthy tissue. Additionally, MindTrace's platform streamlines the process of analyzing brain imaging and behavioral data, reducing the time and effort required by medical teams. The company is supported by the Creative Destruction Lab, reflecting its commitment to advancing neurosurgical care.

Revitalize Energy is a consumer-focused company that specializes in eye drops aimed at alleviating fatigue caused by prolonged screen use. The product features a patented blend of stimulants and amino acids that provides immediate energy and relief from digital eye strain. With just 1-2 drops in each eye, users experience a refreshing effect that helps combat tiredness and enhances comfort, making it an ideal solution for those frequently engaged with digital devices.

Hava Health, Inc. is a biotechnology company based in the United States that specializes in developing innovative solutions for nicotine addiction. The company manufactures a smoking cessation device that includes a connected vape pen designed to assist individuals in their efforts to quit smoking. This device pairs with a smartphone application called Hale, which serves as a digital support tool for users undergoing nicotine de-addiction. Through its focus on combining technology with therapeutic approaches, Hava Health aims to provide effective support for those seeking to overcome nicotine dependence.

MindTrace is a medical software company focused on enhancing neurosurgical procedures through the development of personalized 3D brain maps. By integrating advanced brain imaging with machine learning algorithms, the company creates simulations of surgical resection plans that allow neurosurgeons to predict patients' cognitive outcomes prior to surgery. This innovative approach enables surgeons to optimize the removal of brain tumors while minimizing damage to surrounding healthy tissue. Additionally, MindTrace's platform streamlines the process of analyzing brain imaging and behavioral data, reducing the time and effort required by medical teams. The company is supported by the Creative Destruction Lab, reflecting its commitment to advancing neurosurgical care.

Endolumik makes minimally invasive surgical tools more visible using near infrared technology. Endolumik was headquartered in Morgantown, USA.

Ariel Precision Medicine is an integrated genomics and digital health company based in Pittsburgh, Pennsylvania, that focuses on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases. Founded in 2013, the company develops innovative clinical decision support tools designed to simplify personalized treatment, particularly through its flagship product, ArielDx. This cloud-based platform specifically aids in the diagnosis and management of pancreatic disease, enhancing the capabilities of healthcare providers in both emergency and clinical settings. Ariel Precision Medicine aims to improve patient outcomes by leveraging advanced technology and genomic insights in healthcare.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

Gus Gear specializes in the development and manufacturing of wearable securement clothing designed to protect implanted medical devices. The company's flagship product, the Central Line Vest, effectively prevents damage, breakage, and accidental removal of central catheters. By providing securement solutions for various medical devices, including ostomy pouches and feeding tubes, Gus Gear aims to enhance patient outcomes and quality of life. Their innovative approach enables patients to maintain a higher level of independence and well-being while undergoing medical treatment, allowing them to live their lives to the fullest despite any health challenges.

SovaSage is a digital healthcare platform used to come up with the treatment of sleep apnea patients and other chronic conditions. It was founded in 2020 and is headquartered in Pittsburgh, Pennsylvania.

SwifTAG Systems concepts and products were conceived by active researchers in the medical field who recognized the dramatic inefficiencies of existing small animal management systems and processes. Their mission is to bring high technology and medical research together to drive down costs and increase the time researchers spend doing actual research. They envision laboratories where animal management systems are functional, low maintenance, efficient, and as easy to use as a well-designed smartphone app. They want to see researchers focusing on medical breakthroughs, not on mindless small animal logistics. Their product lines include small animal tags, handheld and tabletop readers, cage and rack readers, whole laboratory management systems, and support software.

RC21X is a company focused on developing a web-based application that measures and monitors brain performance. Founded in 2014 and headquartered in Coraopolis, Pennsylvania, the company offers a user-friendly system that includes 15 brief, game-like modules designed to engage users in assessing their brain health. Targeting both business and consumer markets, RC21X provides its services through clinical settings and self-administered online portals, allowing users to take proactive steps in managing their cognitive wellness. The application aims to help individuals understand their brain function and establish a personal brain performance profile, ultimately promoting neuroplasticity and the development of mental reserves to mitigate age-related cognitive decline. With a diverse team of researchers, medical practitioners, and software designers, RC21X is dedicated to enhancing awareness of brain health as an essential aspect of overall wellness.

Ariel Precision Medicine is an integrated genomics and digital health company based in Pittsburgh, Pennsylvania, that focuses on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases. Founded in 2013, the company develops innovative clinical decision support tools designed to simplify personalized treatment, particularly through its flagship product, ArielDx. This cloud-based platform specifically aids in the diagnosis and management of pancreatic disease, enhancing the capabilities of healthcare providers in both emergency and clinical settings. Ariel Precision Medicine aims to improve patient outcomes by leveraging advanced technology and genomic insights in healthcare.

VIT Initiative, Inc. is a health and safety company based in San Francisco, California, that develops a cloud-enabled Internet of Things (IoT) platform aimed at reducing operational risks and promoting employee health. Founded in 2015, the company focuses on utilizing smart technology to provide real-time coaching and collect data on leading indicators of workplace injuries. This approach helps businesses mitigate risks, enhance operational efficiency, and improve safety compliance, ultimately leading to reduced cycle times and lower injury-related costs. Additionally, VIT Initiative offers automated COVID-19 symptom tracking, further supporting workplace health initiatives. Their products are designed to identify patterns and behaviors that may lead to health problems, allowing for proactive intervention before complications arise.

Gus Gear specializes in the development and manufacturing of wearable securement clothing designed to protect implanted medical devices. The company's flagship product, the Central Line Vest, effectively prevents damage, breakage, and accidental removal of central catheters. By providing securement solutions for various medical devices, including ostomy pouches and feeding tubes, Gus Gear aims to enhance patient outcomes and quality of life. Their innovative approach enables patients to maintain a higher level of independence and well-being while undergoing medical treatment, allowing them to live their lives to the fullest despite any health challenges.

Cassian Solutions, Inc. is a company that develops innovative medication management solutions, including a phone case medication dispenser and a comprehensive application designed to enhance patient compliance. Founded in 2018 and based in Phoenixville, Pennsylvania, the company targets pharmacies, clinical trial organizations, drug manufacturers, and insurers. Its platform addresses critical issues in patient monitoring and data reporting within the specialty medication market, clinical trials, and healthcare systems, aiming to improve health outcomes and reduce healthcare costs. By leveraging the widespread use of smartphones, Cassian Solutions focuses on creating personalized patient journeys that enhance engagement and facilitate real-time communication among all stakeholders involved in medication management.

AbiliLife, Inc. is a Pennsylvania-based company focused on creating biomedical solutions for individuals suffering from neurodegenerative disorders, particularly Parkinson's disease. Incorporated in 2014, AbiliLife designs and manufactures innovative products aimed at enhancing the quality of life for patients. One of its key offerings is Calibrace, a specialized brace that assists patients in restoring equilibrium through a back tensioning system. This product is designed to improve posture, positioning, and balance, providing users with postural stability and relief from discomfort associated with neurodegenerative conditions.

SwifTAG Systems concepts and products were conceived by active researchers in the medical field who recognized the dramatic inefficiencies of existing small animal management systems and processes. Their mission is to bring high technology and medical research together to drive down costs and increase the time researchers spend doing actual research. They envision laboratories where animal management systems are functional, low maintenance, efficient, and as easy to use as a well-designed smartphone app. They want to see researchers focusing on medical breakthroughs, not on mindless small animal logistics. Their product lines include small animal tags, handheld and tabletop readers, cage and rack readers, whole laboratory management systems, and support software.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

Ariel Precision Medicine is an integrated genomics and digital health company based in Pittsburgh, Pennsylvania, that focuses on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases. Founded in 2013, the company develops innovative clinical decision support tools designed to simplify personalized treatment, particularly through its flagship product, ArielDx. This cloud-based platform specifically aids in the diagnosis and management of pancreatic disease, enhancing the capabilities of healthcare providers in both emergency and clinical settings. Ariel Precision Medicine aims to improve patient outcomes by leveraging advanced technology and genomic insights in healthcare.

Cassian Solutions, Inc. is a company that develops innovative medication management solutions, including a phone case medication dispenser and a comprehensive application designed to enhance patient compliance. Founded in 2018 and based in Phoenixville, Pennsylvania, the company targets pharmacies, clinical trial organizations, drug manufacturers, and insurers. Its platform addresses critical issues in patient monitoring and data reporting within the specialty medication market, clinical trials, and healthcare systems, aiming to improve health outcomes and reduce healthcare costs. By leveraging the widespread use of smartphones, Cassian Solutions focuses on creating personalized patient journeys that enhance engagement and facilitate real-time communication among all stakeholders involved in medication management.

Ariel Precision Medicine is an integrated genomics and digital health company based in Pittsburgh, Pennsylvania, that focuses on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases. Founded in 2013, the company develops innovative clinical decision support tools designed to simplify personalized treatment, particularly through its flagship product, ArielDx. This cloud-based platform specifically aids in the diagnosis and management of pancreatic disease, enhancing the capabilities of healthcare providers in both emergency and clinical settings. Ariel Precision Medicine aims to improve patient outcomes by leveraging advanced technology and genomic insights in healthcare.

AbiliLife, Inc. is a Pennsylvania-based company focused on creating biomedical solutions for individuals suffering from neurodegenerative disorders, particularly Parkinson's disease. Incorporated in 2014, AbiliLife designs and manufactures innovative products aimed at enhancing the quality of life for patients. One of its key offerings is Calibrace, a specialized brace that assists patients in restoring equilibrium through a back tensioning system. This product is designed to improve posture, positioning, and balance, providing users with postural stability and relief from discomfort associated with neurodegenerative conditions.

Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior develops a platform that combines wearable devices and machine learning algorithms to monitor key physiological signals such as heart rate and motion. This system, known as Recovery, is designed to support mental health recovery and wellness by delivering timely interventions based on real-time data. By utilizing a software-as-a-service (SaaS) model, Behaivior empowers individuals to maintain their recovery process while enabling care providers to better assist their clients. The integration of AI and behavioral health technology allows Behaivior to recognize patterns in human behavior, ultimately aiming to enhance mental well-being and reduce the incidence of crises, including relapse.

Sharp Edge Labs, Inc. is a biotechnology company based in Pittsburgh, Pennsylvania, specializing in the development of biosensors aimed at enhancing drug discovery and understanding cellular biology. The company creates Fluorogenic Activating Modules (FAMs) that enable precise detection of cellular trafficking, which is essential for high-throughput screening and subsequent analysis. Additionally, Sharp Edge Labs produces single-chain antibody fragments that activate specially designed fluorescent dyes and assays for receptor internalization. Their research focuses on addressing monogenic diseases, trafficking defects, and initiatives driven by patient needs. Key programs include efforts to correct the trafficking defect in deltaF508 CFTR to improve lung function, as well as developing trafficking assays for lysosomal storage disorders and Parkinson's disease. The company was initially known as Sharp Edge Technologies, Inc. and has been operational since its incorporation in 2010.

Ariel Precision Medicine is an integrated genomics and digital health company based in Pittsburgh, Pennsylvania, that focuses on providing precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases. Founded in 2013, the company develops innovative clinical decision support tools designed to simplify personalized treatment, particularly through its flagship product, ArielDx. This cloud-based platform specifically aids in the diagnosis and management of pancreatic disease, enhancing the capabilities of healthcare providers in both emergency and clinical settings. Ariel Precision Medicine aims to improve patient outcomes by leveraging advanced technology and genomic insights in healthcare.

Circadiance LLC is a medical device manufacturing company based in Turtle Creek, Pennsylvania, specializing in respiratory products for individuals with sleep-disordered breathing and those requiring non-invasive ventilation. Founded in 2006, the company develops and markets a range of innovative solutions, including the SleepWeaver all-cloth positive airway pressure masks that enhance comfort during sleep, and the SmartMonitor 2, a portable apnea monitor designed for infants that tracks heart and respiration activity. Additionally, Circadiance offers the SmartMonitor 2 Professional Series for healthcare providers, providing detailed monitoring data, as well as neonatal/pediatric electrodes and the Synergy-E Event Software for analyzing infant apnea data. The NeoPAP system is also part of their product line, designed to treat newborns experiencing respiratory distress syndrome. Circadiance products are distributed through durable medical equipment providers, online retailers, and directly to healthcare professionals, both domestically and internationally.

AbiliLife, Inc. is a Pennsylvania-based company focused on creating biomedical solutions for individuals suffering from neurodegenerative disorders, particularly Parkinson's disease. Incorporated in 2014, AbiliLife designs and manufactures innovative products aimed at enhancing the quality of life for patients. One of its key offerings is Calibrace, a specialized brace that assists patients in restoring equilibrium through a back tensioning system. This product is designed to improve posture, positioning, and balance, providing users with postural stability and relief from discomfort associated with neurodegenerative conditions.

RC21X is a company focused on developing a web-based application that measures and monitors brain performance. Founded in 2014 and headquartered in Coraopolis, Pennsylvania, the company offers a user-friendly system that includes 15 brief, game-like modules designed to engage users in assessing their brain health. Targeting both business and consumer markets, RC21X provides its services through clinical settings and self-administered online portals, allowing users to take proactive steps in managing their cognitive wellness. The application aims to help individuals understand their brain function and establish a personal brain performance profile, ultimately promoting neuroplasticity and the development of mental reserves to mitigate age-related cognitive decline. With a diverse team of researchers, medical practitioners, and software designers, RC21X is dedicated to enhancing awareness of brain health as an essential aspect of overall wellness.

Sharp Edge Labs, Inc. is a biotechnology company based in Pittsburgh, Pennsylvania, specializing in the development of biosensors aimed at enhancing drug discovery and understanding cellular biology. The company creates Fluorogenic Activating Modules (FAMs) that enable precise detection of cellular trafficking, which is essential for high-throughput screening and subsequent analysis. Additionally, Sharp Edge Labs produces single-chain antibody fragments that activate specially designed fluorescent dyes and assays for receptor internalization. Their research focuses on addressing monogenic diseases, trafficking defects, and initiatives driven by patient needs. Key programs include efforts to correct the trafficking defect in deltaF508 CFTR to improve lung function, as well as developing trafficking assays for lysosomal storage disorders and Parkinson's disease. The company was initially known as Sharp Edge Technologies, Inc. and has been operational since its incorporation in 2010.

VIT Initiative, Inc. is a health and safety company based in San Francisco, California, that develops a cloud-enabled Internet of Things (IoT) platform aimed at reducing operational risks and promoting employee health. Founded in 2015, the company focuses on utilizing smart technology to provide real-time coaching and collect data on leading indicators of workplace injuries. This approach helps businesses mitigate risks, enhance operational efficiency, and improve safety compliance, ultimately leading to reduced cycle times and lower injury-related costs. Additionally, VIT Initiative offers automated COVID-19 symptom tracking, further supporting workplace health initiatives. Their products are designed to identify patterns and behaviors that may lead to health problems, allowing for proactive intervention before complications arise.

Pratter is a medical cost savings platform designed to enhance affordability and transparency in healthcare. The platform allows users to access "know before you go" pricing for a range of outpatient services, including blood work, imaging studies like MRIs and CTs, and elective medical procedures such as colonoscopies and cataract surgeries. By providing users with the ability to look up prices based on their zip code, Pratter enables individuals to compare costs among different pharmacies and service providers. This approach empowers users to make informed decisions about their healthcare expenses, ultimately helping them reduce the overall costs of routine medical care. Pratter is offered as an employee benefit, aiming to improve access to affordable healthcare for all.

Accel Diagnostics, LLC specializes in developing innovative medical diagnostics technologies focused on enhancing patient care and monitoring. The company has created the pScreen Card, a disposable, credit card-sized mobile-enabled blood diagnostic platform that accurately detects and quantifies various biomarkers within 30 minutes. This rapid diagnostic capability provides significant improvements in the management of infectious and chronic diseases at the point-of-care while reducing costs. Additionally, Accel Diagnostics is advancing a heart failure test designed for primary care physicians and home patient monitoring, allowing patients to monitor their heart health comfortably at home. This groundbreaking approach enables timely interventions before physical symptoms arise, thereby minimizing the risk of life-threatening events and reducing the frequency of hospitalizations. Founded in 2008 and based in Pittsburgh, Pennsylvania, Accel Diagnostics was previously known as Tropical Health Systems LLC.

AbiliLife, Inc. is a Pennsylvania-based company focused on creating biomedical solutions for individuals suffering from neurodegenerative disorders, particularly Parkinson's disease. Incorporated in 2014, AbiliLife designs and manufactures innovative products aimed at enhancing the quality of life for patients. One of its key offerings is Calibrace, a specialized brace that assists patients in restoring equilibrium through a back tensioning system. This product is designed to improve posture, positioning, and balance, providing users with postural stability and relief from discomfort associated with neurodegenerative conditions.

Accel Diagnostics, LLC specializes in developing innovative medical diagnostics technologies focused on enhancing patient care and monitoring. The company has created the pScreen Card, a disposable, credit card-sized mobile-enabled blood diagnostic platform that accurately detects and quantifies various biomarkers within 30 minutes. This rapid diagnostic capability provides significant improvements in the management of infectious and chronic diseases at the point-of-care while reducing costs. Additionally, Accel Diagnostics is advancing a heart failure test designed for primary care physicians and home patient monitoring, allowing patients to monitor their heart health comfortably at home. This groundbreaking approach enables timely interventions before physical symptoms arise, thereby minimizing the risk of life-threatening events and reducing the frequency of hospitalizations. Founded in 2008 and based in Pittsburgh, Pennsylvania, Accel Diagnostics was previously known as Tropical Health Systems LLC.

Adaptics Ltd. provides Drop, an iPad-connected kitchen scale and digital baking assistant for home bakers. Adaptics adds noticeable vitality to employees and organisations and helps them maintain long-term success. They do this by embedding top-quality service provision in vitalising managers, teams and players. Adaptics considers vitality a strategic resource that forms a basis for desired change in society. They have developed a unique integral approach that includes training, coaching, instructions and online tools. Adaptics has the ambition to address vitality at Champions League level, and to set the standard for corporate health in the Netherlands along with its partners and clients.

Sharp Edge Labs, Inc. is a biotechnology company based in Pittsburgh, Pennsylvania, specializing in the development of biosensors aimed at enhancing drug discovery and understanding cellular biology. The company creates Fluorogenic Activating Modules (FAMs) that enable precise detection of cellular trafficking, which is essential for high-throughput screening and subsequent analysis. Additionally, Sharp Edge Labs produces single-chain antibody fragments that activate specially designed fluorescent dyes and assays for receptor internalization. Their research focuses on addressing monogenic diseases, trafficking defects, and initiatives driven by patient needs. Key programs include efforts to correct the trafficking defect in deltaF508 CFTR to improve lung function, as well as developing trafficking assays for lysosomal storage disorders and Parkinson's disease. The company was initially known as Sharp Edge Technologies, Inc. and has been operational since its incorporation in 2010.

NanoVision Diagnostics, Inc. specializes in the development and commercialization of optical biomarkers for early cancer detection. The company has created a novel electro-optical diagnostic system that performs an optical analysis of standard biopsy slides. This analysis identifies molecular changes in nuclear structure that are not detectable through traditional pathology methods. By enabling medical practitioners to recognize these changes, NanoVision Diagnostics aims to facilitate the early detection and treatment of cancer, ultimately improving patient outcomes. Founded in 2013, the company is headquartered in Kittanning, Pennsylvania.

Accel Diagnostics, LLC specializes in developing innovative medical diagnostics technologies focused on enhancing patient care and monitoring. The company has created the pScreen Card, a disposable, credit card-sized mobile-enabled blood diagnostic platform that accurately detects and quantifies various biomarkers within 30 minutes. This rapid diagnostic capability provides significant improvements in the management of infectious and chronic diseases at the point-of-care while reducing costs. Additionally, Accel Diagnostics is advancing a heart failure test designed for primary care physicians and home patient monitoring, allowing patients to monitor their heart health comfortably at home. This groundbreaking approach enables timely interventions before physical symptoms arise, thereby minimizing the risk of life-threatening events and reducing the frequency of hospitalizations. Founded in 2008 and based in Pittsburgh, Pennsylvania, Accel Diagnostics was previously known as Tropical Health Systems LLC.

Mobile Aspects, headquartered in Pittsburgh, Pennsylvania, specializes in surgical documentation solutions that enhance hospital safety and efficiency. The company offers a healthcare software platform that includes features such as data analytics, endoscope tracking, supply and implant tracking, and tissue tracking. These solutions aim to streamline hospital operations and improve both profitability and patient care. Mobile Aspects is recognized for its impact, with installations at numerous prestigious hospitals in the United States and around the world, including several that rank among the top hospitals according to US News and World Report.