Johnson & Johnson Impact Ventures

CareLoop Health, originating from the University of Manchester, offers a digital platform that supports patients with mental health issues. It enables healthcare professionals to remotely monitor and track patient symptoms, while providing patients with personalized resources to manage their conditions. The platform uses predictive analytics to anticipate future mental health problems, helping to prevent escalation or relapse, and ultimately aims to reduce crises in mental health.

Intra-Cellular Therapies, Inc. is a biopharmaceutical company based in New York that focuses on developing innovative treatments for neuropsychiatric and neurologic diseases, as well as other central nervous system (CNS) disorders. The company’s lead drug candidate, CAPLYTA, is designed to treat schizophrenia and bipolar disorder, along with behavioral disturbances associated with dementia and autism. Additionally, Intra-Cellular Therapies is working on several other drug candidates, including ITI-002, which targets phosphodiesterase type 1; ITI-214 for Parkinson’s disease; and ITI-333 for substance use disorders, pain, and related psychiatric conditions. The company employs a multidisciplinary approach that combines the expertise of medicinal scientists, pharmacologists, and clinical development scientists to create novel therapies. Intra-Cellular Therapies also utilizes its CNSProfile technology platform to generate molecular signatures for drug compounds, aiding in drug discovery and development, and has engaged in collaborations to investigate antidotes for chemical warfare agents.

Alessa Therapeutics, Inc. is a pre-clinical stage biotechnology company based in San Francisco, California, focused on developing localized treatments for solid organ diseases. Founded in 2018, the company specializes in a drug delivery implantable system specifically designed to treat prostate cancer. This innovative system allows for the sustained and localized administration of anti-androgen drugs directly to the tumor in the prostate, minimizing systemic exposure and enhancing treatment efficacy. By concentrating on localized therapies, Alessa Therapeutics aims to improve patient outcomes in the management of various organ diseases.

Tempo Therapeutics is a life science company focused on advancing regenerative medicine through innovative materials and immunomodulation. The company develops precision-engineered, minimally invasive hydrogels that utilize cell-free synthetic materials and geometric technology. These materials are designed to evade the body's immune rejection responses, facilitating the creation of synthetic tissue hybrids across various organs, including skin, bone, heart, and brain. By harnessing the body's regenerative capacity and controlling inflammation, Tempo Therapeutics aims to accelerate healing rates, reduce chronic tissue inflammation, and enhance overall regenerative healing in patients.

V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

Yellow Jersey Therapeutics provides pharmaceutical therapeutic and medical services.

Proteologix is a precision immunology company powered by proprietary multi-specific antibody technologies. The company is dedicated to the discovery and development of safe and convenient therapeutics that target multiple disease-driving pathways to potentially deliver high-bar efficacy for patients with immune-mediated diseases.

Hamilton Health Box operates onsite direct primary and urgent care microclinics tailored for self-insured employers. The company focuses on making healthcare more accessible, convenient, and affordable for employees and their families. By employing a hybrid primary care model, Hamilton Health Box serves small-footprint populations, including small employers and rural communities. Their team of dedicated healthcare professionals acts as advocates for businesses, ensuring that employees receive timely and appropriate care. Through this approach, Hamilton Health Box aims to foster healthier communities while also reducing overall healthcare costs.

Serotiny, Inc. is a biotechnology company based in San Francisco, California, focused on the design and development of multi-domain proteins and therapies aimed at treating cancers and genetic disorders. Founded in 2014, Serotiny leverages a unique platform that integrates synthetic biology with advanced informatics to facilitate the rational design of proteins. The company specializes in creating therapeutic proteins for CAR T-cell therapies and other cellular therapies. By harmonizing computational protein design, high-throughput cellular assays, and next-generation sequencing, Serotiny employs a cross-disciplinary approach that incorporates expertise from immunology, machine learning, software engineering, and bioinformatics. This innovative methodology enables the development of gene and cell therapies with improved safety and efficacy through novel control mechanisms and engineered functionalities.

Health In Her HUE is a digital platform dedicated to connecting Black women and women of color with culturally sensitive healthcare providers. Its mission focuses on reducing racial health disparities by leveraging technology, media, and community resources to enhance health outcomes for these populations. The platform offers access to evidence-based, culturally attuned health content and fosters community support, enabling users to comfortably engage with healthcare professionals who understand their unique needs. By prioritizing culturally relevant care and information, Health In Her HUE aims to empower women to take charge of their health and well-being.

Ambrx, Inc. is a clinical-stage biopharmaceutical company based in La Jolla, California, specializing in the development of engineered precision biologics through an expanded genetic code technology platform. This innovative approach enables the incorporation of synthetic amino acids into proteins, facilitating the creation of next-generation therapeutics. Ambrx focuses on various product candidates, including antibody drug conjugates (ADCs), bispecific antibodies, targeted immuno-oncology treatments, and long-acting therapeutic peptides aimed at addressing metabolic and cardiovascular diseases. The company has a robust development pipeline featuring multiple clinical and preclinical programs, with its lead candidate ARX788 among them. Ambrx also collaborates with other organizations, such as MabSpace Biosciences and BeiGene, to enhance its research and development efforts in oncology and other therapeutic areas. Founded in 2003, Ambrx is committed to advancing the efficacy and safety of new biologic therapies for patients.

54 Collective, established in 2018, is a South Africa-based venture capital firm that invests in and supports African tech startups, primarily focusing on sectors such as fintech, health tech, agritech, logistics, and e-commerce. The company provides catalytic capital alongside value-add support and leverages its global network to help founders scale their businesses. 54 Collective, a business-focused investor, integrates impact considerations into all its operations, aiming to generate returns for investors while enabling entrepreneurs to grow their ventures.

Mamotest is a technology-driven company focused on improving breast cancer outcomes through early diagnosis and patient guidance. By leveraging artificial intelligence, Mamotest has developed a collaborative platform that democratizes access to screening and diagnosis, facilitating an efficient path to treatment. The company's innovative approach integrates telediagnosis and ensures complete traceability of the patient journey, aiming to transition healthcare from a reactive model to one that prioritizes prevention and health maintenance. Operating in Spain, Argentina, and Mexico, Mamotest's mission is to significantly reduce breast cancer mortality rates, thereby enhancing the overall quality of care for patients.

SwipeRx is a digital platform designed for pharmacies that connects pharmaceutical manufacturers, pharmacies, and patients. It offers specialized healthcare logistics, negotiated pricing, and financing solutions, creating the largest digital pharmacy purchasing network. The platform generates insights that enhance collaboration among pharmacies, improve pharmacist education, and strengthen market access. Additionally, it optimizes commercial strategies and boosts operational efficiencies, providing real-time access to patient and sales data. By doing so, SwipeRx enables its clients to improve patient affordability, access, and adherence to medications.

Abiomed is a company that specializes in mechanical circulatory support devices aimed at assisting heart failure patients. It develops, manufactures, and markets products designed to improve blood flow and temporarily aid the heart's pumping function, allowing the organ to rest, heal, and recover. Its devices are primarily utilized in cardiac catheterization labs by interventional cardiologists and in surgical settings by heart surgeons. These products are essential for patients requiring hemodynamic support before, during, or after procedures such as angioplasty and heart surgery. A significant portion of Abiomed's revenue is generated from its Impella product portfolio, which includes advanced percutaneous micro heart pumps equipped with integration motors and sensors.

SwipeRx is a digital platform designed for pharmacies that connects pharmaceutical manufacturers, pharmacies, and patients. It offers specialized healthcare logistics, negotiated pricing, and financing solutions, creating the largest digital pharmacy purchasing network. The platform generates insights that enhance collaboration among pharmacies, improve pharmacist education, and strengthen market access. Additionally, it optimizes commercial strategies and boosts operational efficiencies, providing real-time access to patient and sales data. By doing so, SwipeRx enables its clients to improve patient affordability, access, and adherence to medications.

IndyGeneUS AI is a Black-Owned and Service-Disabled Veteran-Owned Small Business specializing in genomics. The company is developing the world's largest blockchain-encrypted repository of clinical and genomic data specifically for indigenous and diasporic African populations. Utilizing proprietary technology, IndyGeneUS AI integrates multi-omics data, electronic healthcare records, and scientific literature to identify novel signature sequences, biomarkers, and polygenic risk scores. This extensive data repository aims to enhance disease prevention, detection, and drug discovery while promoting clinical disease management and precision health equity. By focusing on the unique genomic characteristics of these populations, the company seeks to improve the efficiency and quality of healthcare delivery.

Lucia Health Guidelines is a developer of a clinical decision support tool that utilizes cloud computing and machine learning to enhance performance ethics in clinical settings. The company primarily focuses on improving the diagnosis and treatment of Atrial Fibrillation (AFib) in emergency departments. By providing clinicians with tools to accurately identify AFib and initiate recommended treatments, Lucia Health Guidelines aims to prevent strokes, improve patient outcomes, and reduce overall healthcare costs. Their technology is designed to ensure adherence to clinical guidelines, ultimately enabling healthcare professionals to deliver timely and effective care.

Radical Health is a company focused on promoting health equity through technology and community engagement. It utilizes AI-enabled tools to facilitate meaningful conversations about health, aiming to enhance individuals' understanding of their healthcare experiences. By combining workshops and training programs, Radical Health fosters deeper discussions around the social determinants of health for both communities and healthcare providers. The company also offers Radical Relay, an AI-based chat application that empowers individuals to know their rights, particularly during pregnancy. Through its innovative approach, Radical Health seeks to equip and empower people to advocate for themselves within the healthcare system.

TQIntelligence, Inc., established in 2016 and based in Atlanta, Georgia, specializes in voice-based artificial intelligence for mental health assessment. The company's platform integrates diverse data sources to provide cognitive insights, enabling risk stratification, tracking treatment outcomes, and personalized behavioral interventions. Key products include TQ-Intelligence, which offers insights from voice/speech analytics and other psychometrically validated instruments, and TQ Analytics, leveraging existing EMR data for actionable insights. The platform features machine learning analytics, knowledge graph, and real-time prediction capabilities to support healthcare professionals in diagnosing mental health issues more effectively, particularly for children who may struggle to communicate their distress.

Ayana Therapy is a telehealth platform dedicated to providing mental health services to marginalized and intersectional communities. By utilizing a smart matchmaking algorithm, the platform connects users with licensed therapists who share an understanding of their cultural backgrounds and identity traits, including race, gender identity, class, sexuality, and ethnicity. Ayana Therapy aims to address the significant barriers faced by people of color and LGBTQ+ individuals in accessing mental health care, such as high costs, stigma, and a lack of cultural competency within the healthcare system. The platform fosters a user-friendly environment that offers a safe space for individuals whose voices have been historically dismissed or neglected, ensuring that they receive the mental health support they need.

Patient Orator is a mental health company that focuses on enhancing communication between patients and healthcare providers, particularly for individuals from marginalized groups. Through its innovative mobile application, the company facilitates open and fluid conversations, allowing users to discuss their health concerns and social needs in a safe and judgment-free environment. The platform emphasizes preventative medicine and shared decision-making, striving to improve patient experiences and overall population health. By addressing the unique challenges faced by underserved communities, Patient Orator aims to increase access to essential healthcare resources, ensuring that all individuals receive equitable treatment regardless of their race, ethnicity, gender, nationality, or insurance status.

Momenta Pharmaceuticals, Inc. is a biotechnology company headquartered in Cambridge, Massachusetts, that focuses on the discovery and development of innovative therapeutics for rare immune-mediated diseases. The company's product pipeline includes novel therapeutics such as M281, a fully-human monoclonal antibody targeting the neonatal Fc receptor to reduce circulating IgG antibodies; M254, aimed at treating inflammatory diseases; and M230, a recombinant trivalent IgG1 Fc multimer designed for enhanced therapeutic activity. Additionally, Momenta has developed complex generic products, including M-Enoxaparin, a generic version of Lovenox, and M356, a generic of Copaxone for multiple sclerosis. Momenta also has biosimilar programs, including M923, a biosimilar of HUMIRA, and M710, a biosimilar of EYLEA for various eye conditions. Despite previously pursuing the generics and biosimilars market, the company shifted its focus to innovative drug development, with several promising candidates in the pipeline for autoimmune diseases. Momenta was founded in 2001 and operates as a subsidiary of Johnson & Johnson.

TARIS Biomedical, Inc. is a therapeutically focused urology company based in Lexington, Massachusetts, established in 2008. The company specializes in developing innovative treatments for challenging bladder diseases, including bladder cancer and overactive bladder. TARIS Biomedical's proprietary system is designed to continuously release medications directly into the bladder over extended periods, ranging from weeks to months. This technology is administered through minimally invasive, in-office procedures, allowing for customized drug delivery that aligns with the specific needs of various bladder conditions. As of December 2019, TARIS Biomedical operates as a subsidiary of Janssen Research & Development, LLC.

Verb Surgical Inc. is a company based in Santa Clara, California, founded in 2015 and operates as a subsidiary of Johnson & Johnson Innovation - JJDC, Inc. The company focuses on developing a digital surgery platform that integrates robotics, advanced visualization, advanced instrumentation, data analytics, and connectivity. This platform aims to enhance surgical practices, improve patient outcomes, and reduce overall healthcare costs. By leveraging innovative technologies and data-driven insights, Verb Surgical seeks to democratize surgery and meet the evolving needs of operating room professionals.

KnowRX Health is a developer of a cloud-based digital healthcare platform designed to enhance therapeutic care through personalized patient engagement. The platform utilizes machine learning technology, Maestro ML™, to create tailored care circles that facilitate clinical trial participation, improve medication adherence, and conduct focused surveys. It engages patients in daily wellness activities, encompassing nutritional, psychological, and physical health. The KnowRX platform serves as a resource for both patients and healthcare providers, offering critical drug information and updated clinical trial reports to inform therapy decisions. Additionally, it provides access to counseling, genomics data for treatment compatibility, nutritional guidance, and educational resources, all aimed at optimizing treatment outcomes and empowering patients in their self-care journey.

M-Scan is a medical device company focused on developing portable mobile ultrasound devices specifically designed for pregnant mothers. Its mission is to enhance the quality of human life through innovation and integrity, particularly within communities. M-Scan's technology leverages smart device capabilities to improve safety for pregnant women by facilitating early detection and management of risk factors associated with maternal and neonatal mortality. This approach is particularly beneficial in resource-scarce environments, where the ability to monitor and address complications can significantly impact health outcomes for both mothers and their children.

Uganics is a manufacturer specializing in organic mosquito repellent products, including soaps, candles, lotion bars, and essential oils. Their primary focus is producing affordable and long-lasting organic mosquito repellent soap, aiming to protect children under five in rural communities from mosquito bites, particularly in areas at risk of malaria.

Tiny Hearts specializes in the production and supply of phototherapy treatment essentials and other medical equipment to hospitals. They offer innovative, solar-powered phototherapy units and reusable accessories, designed for ease of use and affordability, primarily serving healthcare providers in Sub-Saharan Africa. Customer inquiries are handled via phone, email, and online applications.

DayTwo Ltd. is a precision nutrition company based in Tel Aviv-Yafo, Israel, that focuses on leveraging gut microbiome analysis to provide tailored health solutions for metabolic diseases such as diabetes, prediabetes, clinical obesity, and non-alcoholic fatty liver disease (NAFLD). Founded in 2015, DayTwo utilizes a web-based platform that offers personalized dietary recommendations through its innovative Food Prescriptions™, which are designed to help individuals manage their blood sugar levels and improve overall health. By sequencing gut microbiomes, the company identifies how different foods affect each person, allowing for customized nutrition plans. DayTwo's virtual care model is supported by Certified Diabetes Care and Education Specialists and Registered Dietitians, who engage with patients through a smartphone application to track progress and ensure adherence to the dietary recommendations.

Oncochain is focused on developing a real-world data platform specifically for oncology, aimed at standardizing and aggregating anonymized data from cancer patients. This platform facilitates the generation of valuable analytics that support research initiatives for pharmaceutical companies and enhance value-based care for healthcare providers. Utilizing a proprietary web-based electronic health record system tailored for oncology, Oncochain creates operational data repositories that streamline the flow of information between providers and improve the skills of oncology professionals. The company significantly contributes to research by reducing recruitment times for clinical trials and establishing frameworks for multi-centric study design and implementation. Through its software-as-a-service analytics tool, Oncochain delivers essential real-world data insights to clients, including cancer centers, clinicians, and life sciences organizations, thereby accelerating research and optimizing treatment outcomes.

Auris Health, Inc. is a medical technology company based in Redwood City, California, that specializes in the development of robotic systems for diagnostic and therapeutic procedures. Founded in 2007, the company is known for its Monarch Platform, which enhances endoscopic procedures by utilizing flexible robotics, advanced imaging technology, and micro-instrumentation. This platform allows for minimally invasive access to the body through natural openings using small cameras and tools, thereby improving patient outcomes and potentially reducing healthcare costs. Additionally, Auris Health is working on a dual-arm microsurgical system designed for ophthalmic surgery, further expanding its focus on innovative robotic solutions for various medical applications. Auris Health operates as a subsidiary of Johnson & Johnson.

Ci:z Holdings Co., Ltd. is a Japan-based company engaged in the development, manufacturing, and sale of cosmetics, health foods, and beauty care products. Founded in 1999 and headquartered in Tokyo, the company operates primarily through two segments: cosmetics and health food. The cosmetics segment includes a diverse range of products designed for various skin issues, featuring brands such as Dr.Ci:Labo, Labo Labo, and Genomer, which contribute significantly to the company's revenue. The health food segment offers nutritional supplements and other products aimed at enhancing health and beauty from within. Ci:z Holdings distributes its products through mail order, wholesale channels, and directly operated stores, as well as through retail outlets such as drug stores and department stores, both in Japan and internationally.

Zarbee's, Inc. is a health-focused company that manufactures and sells a range of products designed for cough and throat relief, immune support, and general wellness, including vitamins and supplements for both children and adults. Founded in 2007 and headquartered in Draper, Utah, Zarbee's aims to provide clinically proven, natural health solutions for families. The company distributes its products through various retail channels, both in physical stores and online. Additionally, Zarbee's has a location in Greenwich, Connecticut, and operates as a subsidiary of Johnson & Johnson Consumer Inc.

Cue Health Inc. is a healthcare technology company based in San Diego, California, specializing in the development and manufacturing of diagnostic screening devices for home use. Founded in 2010, the company offers a connected diagnostic platform known as the Cue Health Monitoring System, which allows users to conduct self-serve tests that provide lab-quality results. This platform enables individuals to track key health indicators, including inflammation, vitamin D, fertility, influenza, and testosterone, through a user-friendly device that connects to a smartphone app. The Cue app not only displays test results but also integrates data on lifestyle factors such as activity and sleep, facilitating a comprehensive view of health at a molecular level. Additionally, Cue Health provides various services for healthcare professionals, including tools for managing patient test histories and telemedicine consultations. The company's innovative approach empowers consumers and healthcare providers alike to access critical health information easily and effectively.

Dreem is a neurotechnology company focused on enhancing human potential through innovative consumer technology. Its primary product is a wearable device that improves the quality of deep sleep by monitoring brainwaves and analyzing sleep patterns. The device employs sound stimulation to extend deep sleep duration, which can lead to improved daily performance. By utilizing machine learning algorithms, Dreem's headband provides real-time analysis of sleep stages and delivers personalized insights and tips that adapt based on individual sleeping habits. This approach aims to help users achieve faster sleep onset, longer deep sleep, and a refreshed awakening.

Orthotaxy is a medical technology company based in Gières, France, specializing in the development of software-enabled surgery solutions. The company focuses on designing and creating computer-assisted platforms that enhance surgical procedures through personalized medical devices. Driven by a team of qualified and experienced engineers, Orthotaxy emphasizes quality assurance in its development processes, ensuring that clients receive innovative technologies that optimize surgical outcomes. Through its advanced solutions, Orthotaxy aims to improve the efficiency and effectiveness of surgical interventions in the healthcare industry.

Bloomlife is a pioneering women's health company focused on enhancing maternal care through innovative technology. By integrating connected devices with cloud-based data analytics, Bloomlife aims to improve access to care for expectant mothers and empower them with crucial information. The company's remote maternal care platform facilitates the monitoring of high-risk pregnancies, allowing obstetricians to better assess maternal and fetal risks and educate patients effectively. Bloomlife’s solutions reduce the need for frequent in-person appointments and lengthy referral processes, thus streamlining the management of pregnancy complications. With a commitment to redefining maternal health, Bloomlife seeks to become the leading provider of remote care for expectant women worldwide, ultimately improving health outcomes for mothers and babies.

Prapela is a pediatric medical device company focused on enhancing the health of newborns through noninvasive stimulation therapy. Its primary product, a reusable pad designed for placement in hospital bassinets or incubators, provides gentle stimulation that aids in regulating breathing control and improving oxygenation. By addressing common clinical issues such as irregular breathing and low oxygen levels, Prapela aims to improve cardiorespiratory outcomes for infants while reducing the need for pharmacotherapy and minimizing the duration of conventional treatments. Since its inception, Prapela has gained recognition as a leading innovator in the pediatric medical device sector, collaborating with neonatologists, the National Institutes of Health, and the FDA to advance its mission of improving newborn health.

DayTwo Ltd. is a precision nutrition company based in Tel Aviv-Yafo, Israel, that focuses on leveraging gut microbiome analysis to provide tailored health solutions for metabolic diseases such as diabetes, prediabetes, clinical obesity, and non-alcoholic fatty liver disease (NAFLD). Founded in 2015, DayTwo utilizes a web-based platform that offers personalized dietary recommendations through its innovative Food Prescriptions™, which are designed to help individuals manage their blood sugar levels and improve overall health. By sequencing gut microbiomes, the company identifies how different foods affect each person, allowing for customized nutrition plans. DayTwo's virtual care model is supported by Certified Diabetes Care and Education Specialists and Registered Dietitians, who engage with patients through a smartphone application to track progress and ensure adherence to the dietary recommendations.

Actelion Pharmaceuticals, established in 1997 and headquartered in Allschwil, Switzerland, is a biopharmaceutical company specializing in the discovery, development, and commercialization of low molecular weight drugs for unmet medical needs. Its primary focus is on pulmonary arterial hypertension (PAH), offering a range of treatments including Tracleer, Opsumit, Uptravi, Ventavis, and Veletri, which cater to different stages of the disease and administration methods. Additionally, Actelion provides Zavesca for Gaucher disease and Valchlor for a rare form of blood cancer. The company markets its products globally and has built a robust commercial infrastructure for its approved orphan drugs. Actelion supplements its internal pipeline through strategic in-licensing and acquisitions, operating as a subsidiary of Johnson & Johnson.

RayIoT Solutions Inc. specializes in developing innovative monitoring devices designed for health and safety. One of its flagship products, Raybaby, is a sophisticated baby monitor that tracks a child's respiration and sleep patterns, providing alerts for elevated respiratory rates that may indicate fever or other health issues. Equipped with an infrared video camera, Raybaby allows for live video streaming in complete darkness, along with built-in speakers and audio monitoring through a highly sensitive microphone. In addition, the company offers a wall-mounted monitoring device that transforms any space into a mini intensive care unit, continuously monitoring breathing rates and enabling the early detection of respiratory distress for patients in self-quarantine or quarantine facilities.

Neurotrack Technologies, Inc., established in 2012 and headquartered in Redwood City, California, specializes in digital health solutions for early detection and ongoing monitoring of cognitive impairment, particularly Alzheimer's and other dementias. The company offers a computer-based cognitive test, validated clinically and guided by patients, which can be administered in clinics or at home, fitting various workflows. Neurotrack's proprietary technology has been recognized with 11 patents and is registered as an FDA Class II medical device. The company has published 27 peer-reviewed papers, demonstrating its commitment to scientific rigor and innovation in transforming dementia diagnosis and management.

Abbott, established in 1910, is a global healthcare company with a diverse portfolio of products. It is a leader in pharmaceuticals, with notable brands like Norvir (HIV treatment), Synthroid (synthetic thyroid hormone), and Humira (rheumatoid arthritis drug). In diagnostics, Abbott Molecular specializes in molecular diagnostics, offering over 350 products for infectious disease, oncology, and genetics. Abbott's medical devices division is prominent in cardiovascular and diabetes care, with products such as pacemakers, glucose monitors, and neuromodulation devices. Additionally, Abbott is a significant player in eye care, ranking first in LASIK and second in cataract surgery with its TECNIS platform. The company's nutritional division provides a range of products for both adults and infants. Abbott India, a subsidiary, focuses on women's health, gastroenterology, and metabolic disorders. Approximately 60% of Abbott's sales come from outside the United States.

Ci:z Holdings Co., Ltd. is a Japan-based company engaged in the development, manufacturing, and sale of cosmetics, health foods, and beauty care products. Founded in 1999 and headquartered in Tokyo, the company operates primarily through two segments: cosmetics and health food. The cosmetics segment includes a diverse range of products designed for various skin issues, featuring brands such as Dr.Ci:Labo, Labo Labo, and Genomer, which contribute significantly to the company's revenue. The health food segment offers nutritional supplements and other products aimed at enhancing health and beauty from within. Ci:z Holdings distributes its products through mail order, wholesale channels, and directly operated stores, as well as through retail outlets such as drug stores and department stores, both in Japan and internationally.

Vogue International LLC, founded in 1987 and based in Clearwater, Florida, is a leading manufacturer and distributor of hair care and personal care products. The company's portfolio includes the FX™ line of hair styling products, the award-winning OGX® collection of shampoos, conditioners, and styling/treatment items, and the OGX® Bath & Body Collection. Vogue's products are distributed to major retailers through food, drug, and mass channels both domestically in the U.S. and internationally in 42 countries. The company is known for its innovative approach and commitment to using high-quality ingredients and environmentally friendly packaging.

Suncayr Inc., based in Mississauga, Canada, specializes in innovative sun protection technology. The company has developed a color-changing sticker known as "SPOT," which is designed to indicate when sunscreen is no longer effective in blocking ultraviolet rays. Users apply the sticker directly to their skin before applying sunscreen. While the sunscreen provides adequate protection, the sticker remains clear; however, it changes to purple when UV exposure occurs, signaling that reapplication of sunscreen is necessary. This product aims to enhance safety and confidence for individuals and families enjoying outdoor activities in the sun.

Tesaro, Inc. is an oncology-focused biopharmaceutical company established in 2010 and headquartered in Waltham, Massachusetts. The company is dedicated to developing and commercializing cancer therapeutics and supportive care products. Its primary offerings include ZEJULA, a potent oral poly polymerase inhibitor for the maintenance treatment of recurrent ovarian, fallopian tube, or primary peritoneal cancer, and VARUBI, a neurokinin-1 receptor antagonist designed to prevent chemotherapy-induced nausea and vomiting. Additionally, Tesaro is engaged in the development of several immunotherapy antibody candidates, including TSR-042, TSR-022, and TSR-033, all currently in phase I clinical trials. The company collaborates with various organizations, such as AnaptysBio, Janssen Biotech, and Merck Sharp & Dohme, to enhance its research and development efforts. Tesaro aims to leverage its management team's expertise to identify and commercialize innovative treatments that improve the lives of cancer patients. As of January 2019, Tesaro operates as a subsidiary of GlaxoSmithKline.

Novira Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Doylestown, Pennsylvania, focused on the discovery and development of antiviral drugs targeting chronic hepatitis B (HBV) and human immunodeficiency virus (HIV) infections. Founded in 2006, the company specializes in creating first-in-class oral therapeutics that inhibit the viral capsid, offering innovative treatment options both as standalone therapies and in combination with existing treatments. Novira's antiviral drugs aim to address significant limitations associated with current therapies for chronic HBV and HIV, particularly the challenges of drug resistance and the need for lifelong treatment. By employing a novel mechanism of action, Novira Therapeutics seeks to provide more effective and potentially curative solutions for these global health issues. As of December 2015, Novira operates as a subsidiary of Johnson & Johnson.

NeoStrata Company, Inc., based in Princeton, New Jersey, develops and markets a wide variety of therapeutic and cosmetic dermatological products. Founded in 1988, the company is renowned for its innovative use of alpha hydroxy acid technology, which was pioneered by its founders, Drs. Van Scott and Yu, who demonstrated the significant benefits of these acids for skin rejuvenation. NeoStrata's product portfolio includes anti-aging systems, concealing treatment cosmetics, and topical solutions for various skin conditions such as psoriasis, acne, and hyperpigmentation. The company's offerings encompass cleansers, toners, moisturizers, serums, and specialized kits, catering to diverse skin types and concerns. NeoStrata products are distributed globally through consumer outlets, medical professionals, pharmacies, and beauty retailers, reflecting its commitment to providing clinically-proven skincare solutions. The company also operates as a subsidiary of Johnson & Johnson Consumer Inc.

Inter-Grosshandel offers wide range of wholesale brand clothing

U.K.-based cardiovascular drug startup

Jagdale Industries Pvt Ltd(JIPL) is a part of the well-established and one-of-the-oldest industrial family group of Bengaluru: ‘The Jagdale family’. The roots of Jagdale go back to 1939 when Associated Drugs Company Ltd., was set up and to the contributions of Late Shri. Radhakrishna Jagdale, founder Jagdale group. JIPL has pioneered several products including unique food, beverage, nutraceutical and pharmaceutical formulations, in line with the nation’s needs and market requirements.

Alios BioPharma is focused on discovering and developing innovative antiviral therapies aimed at treating both acute and chronic viral infections. The company utilizes a range of proprietary platform technologies, including small molecule activators of innate immunity, phosphate-protected nucleotide prodrug chemistry, and glycoprotein-engineering of interferons. These technologies enable the development of distinct therapeutic products targeting serious viral conditions such as chronic hepatitis B and C, HIV, and respiratory viruses, including pandemic influenza and emerging diseases like SARS. Alios BioPharma's approach is supported by a proprietary chemical library of nucleoside analogs and advanced virology-based screening systems, positioning the company as a key player in the field of antiviral therapeutics.

DePuy Synthes is a leading manufacturer of orthopedic and medical technology equipment focused on enhancing patient recovery and mobility. The company produces a wide range of products designed for various specialties, including joint reconstruction, trauma, craniomaxillofacial surgery, spinal surgery, and sports medicine. Its offerings encompass surgical implants and biomaterials for fixation and orthopedic procedures, including systems for clavicle and olecranon plates, spinal solutions, and advanced surgical tools. Additionally, DePuy Synthes provides comprehensive services, such as advanced case management, loaner programs, and personalized solutions through its Trumatch platform. The company is dedicated to improving surgical outcomes and patient care through innovative products and services.

Aragon Pharmaceuticals is a discovery-stage small molecule company dedicated to developing therapeutics for hormone-resistant cancers, specifically targeting prostate and breast cancer. The company specializes in anti-endocrine therapies that leverage nuclear receptor biology, medicinal chemistry, and drug discovery methodologies. Aragon aims to identify and create selective androgen receptor degraders for prostate cancer and selective estrogen receptor degraders for estrogen-sensitive breast cancer, addressing the need for effective treatments in these challenging areas of oncology.

Elsker provides products to care for the skin health of babies. They provide body wash, shampoo, clothes, and talcum powder for babies. They also offer products for pregnant mothers.

Calibra Medical, Inc. develops medical devices and technologies in the diabetes sector. It offers insulin delivery devices. The company was formerly known as Seattle Medical Technologies, Inc. Calibra Medical, Inc. was founded in 2004 and is based in Redwood City, California.

SterilMed is a contracting manufacturer specializing in the reprocessing, remanufacturing, and repair of medical devices and equipment. The company offers refurbishing services for a range of medical equipment, including flexible endoscope systems, power equipment, and surgical instruments. SterilMed serves over 1,700 healthcare facilities across North America, providing essential services that extend the lifecycle of medical devices while ensuring compliance with safety and quality standards. Through its focus on sustainability and cost-effectiveness, SterilMed plays a significant role in the healthcare industry by enabling facilities to maintain high-quality standards while managing operational costs.

Crucell N.V. is a global biopharmaceutical company dedicated to the research, development, production, and marketing of vaccines, proteins, and antibodies aimed at preventing and treating infectious diseases. The company offers a diverse portfolio of vaccines, including those for hepatitis B, a fully-liquid vaccine that addresses five significant childhood diseases, and a virosome-adjuvanted vaccine for influenza. Additionally, Crucell markets travel vaccines, which include the only oral anti-typhoid vaccine, an oral cholera vaccine, and the only aluminum-free hepatitis A vaccine available. Its products are distributed in both public and private markets worldwide, reflecting the company's commitment to combating infectious diseases through innovative biopharmaceutical solutions.

Micrus Endovascular Corporation develops and manufactures both implantable and disposable medical devices used in the treatment of cerebral vascular diseases. Micrus Endovascular develops products that can be used by interventional neuroradiologists, interventional neurologists, and endovascularly trained neurosurgeons to treat both cerebral aneurysms responsible for hemorrhagic stroke and intracranial atherosclerosis, which may lead to ischemic stroke. The Micrus Endovascular product lines enable physicians to gain access to the brain in a minimally invasive manner through the vessels of the arterial system. It also sells stents, balloon catheters, access devices such as guide catheters, microcatheters, guidewires, and accessory products used in conjunction with its microcoils. Micrus Endovascular Corporation wasfounded in 1996 and is based in San Jose, California. As of September 27, 2010, Micrus Endovascular LLC operates as a subsidiary of Codman & Shurtleff, Inc.

Acclarent, Inc. is a medical device company focused on developing innovative technologies for ear, nose, and throat (ENT) patients. The company specializes in balloon sinuplasty devices, which are minimally invasive tools designed to assist physicians in treating chronic sinusitis. These devices enable doctors to navigate sinus anatomy effectively, facilitating the opening of blocked sinus ostia and passageways to promote proper sinus drainage. Acclarent's Balloon Sinuplasty technology and associated Relieva product portfolio provide alternatives to traditional endoscopic surgical methods. The company's devices received FDA clearance and were commercially launched in the United States in 2005, marking a significant advancement in the treatment options available for patients with sinus-related conditions.

Crucell N.V. is a global biopharmaceutical company dedicated to the research, development, production, and marketing of vaccines, proteins, and antibodies aimed at preventing and treating infectious diseases. The company offers a diverse portfolio of vaccines, including those for hepatitis B, a fully-liquid vaccine that addresses five significant childhood diseases, and a virosome-adjuvanted vaccine for influenza. Additionally, Crucell markets travel vaccines, which include the only oral anti-typhoid vaccine, an oral cholera vaccine, and the only aluminum-free hepatitis A vaccine available. Its products are distributed in both public and private markets worldwide, reflecting the company's commitment to combating infectious diseases through innovative biopharmaceutical solutions.

Cougar Biotechnology, Inc

Omrix Biopharmaceuticals, Inc., a biopharmaceutical company, develops, manufactures, and markets biological products for the biosurgical and immunotherapy markets.

Founded in 1998 by Dr. Victor Strecher, HealthMedia specializes in developing scalable behavior change interventions that emulate the effectiveness of health coaching without the need for a live coach. The company creates innovative programs tailored for health and wellness, disease management, behavioral health, and medication compliance. HealthMedia collaborates with pharmaceutical firms and medical device manufacturers to address various health challenges, including drug and alcohol addiction, mental illness, cardiovascular diseases, hypertension, and HIV/AIDS. Through its unique methodology and technology, HealthMedia delivers impactful outcomes comparable to traditional health coaching, making it a leader in the field of digital health solutions.

Beijing Dabao Cosmetics Co., Ltd. is a Beijing-based manufacturer specializing in the development, production, and sale of herbal cosmetic products. The company offers a diverse range of items, including face wash, moisturizer, sunscreen, shampoo, and various other skin care products. In addition to serving the domestic market, Dabao Cosmetics exports its products internationally, positioning itself as a key player in the cosmetic industry.

Conor MedSystems specializes in the development of controlled drug delivery technologies for vascular applications, primarily focusing on drug-eluting stents designed to treat coronary artery disease and restenosis. The company aims to enhance the effectiveness of vascular stents by incorporating mechanisms that allow for localized drug delivery to both coronary and peripheral vessels. Through its innovative approach, Conor MedSystems seeks to improve patient outcomes in the management of vascular conditions.

InnerPulse, Inc. develops technology, devices, software protocols, and procedures to transform the treatment of cardiac arrhythmias. It offers invasive treatment that enables physicians to implant the life-saving Percutaneous Implantable Cardioverter Defibrillator within the patient's vascular system. InnerPulse, Inc. was formerly known as Interventional Rhythm Management, Inc.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

Groupe Vendome SA manufactures adult and baby skin care products.

Peninsula Pharmaceuticals, Inc. is a specialty pharmaceutical company dedicated to the licensing, development, and commercialization of anti-infective therapies aimed at treating life-threatening infections in North America and Europe. The company's primary focus is on its lead product candidate, doripenem, a broad-spectrum antibiotic classified as a carbapenem. Currently, Peninsula is conducting six Phase III clinical trials for doripenem, which has also received Fast Track designation from the U.S. Food and Drug Administration for the treatment of nosocomial pneumonia, including ventilator-associated pneumonia. The company was acquired by Johnson & Johnson, a global leader in healthcare products and services. As a privately held biopharmaceutical entity, Peninsula Pharmaceuticals concentrates on advancing antibiotics to address critical infection-related health challenges.

Transform Pharmaceuticals was a pharmaceuticals company specializing in the discovery of improved formulations and novel crystalline forms of drug molecules. Transform’s product portfolio included Topiramate, an anti-epileptic drug. The company was acquired by Johnson & Johnson in 2005. The company was founded in 1998.

3-Dimensional Pharmaceuticals is a drug discovery company that develops advanced technologies to enhance and expedite the drug discovery process. By integrating high-throughput screening, combinatorial chemistry, and structure-based design, the company leverages genome sequencing targets to create efficient and innovative drug discovery solutions.

TopSpin Medical has developed a groundbreaking technology for high-resolution MRI imaging using an IntraVascular MRI (IVMRI) catheter specifically designed for the coronary arteries. This innovative catheter eliminates the need for expensive and cumbersome external MRI setups by miniaturizing essential MRI components to less than 2 millimeters in size. The advanced technology allows for precise imaging within the coronary arteries, revolutionizing the field of medical imaging and providing a more efficient and cost-effective solution for clinicians and patients alike.

Tibotec is a biopharmaceutical company focused on developing anti-viral treatments, with several promising compounds in development for the treatment of infectious diseases including HIV.

LXN Corporation is a medical technology company that develops, manufactures, and markets products to help people with diabetes better manage their disease. The company offers GlucoProtein, a home-based test that measures overall glucose control. It allows patients and healthcare professionals to better monitor the overall effectiveness of diabetes treatments and make timely and effective therapy changes. LXN Corporation was founded in 1994 and is based in San Diego, California.

BabyCenter is a digital parenting platform and subsidiary of Johnson & Johnson, dedicated to providing information and support for parents and parents-to-be throughout the journey of parenthood. The website offers resources on conception, pregnancy, childbirth, and early childhood, catering to the diverse needs of families. Alongside its companion site, ParentCenter, which focuses on children aged 2 to 8, BabyCenter helps users navigate parenting challenges with various tools, including pregnancy calendars, baby name finders, and due date calculators. The platform features buying guides and product comparisons to assist parents in making informed purchasing decisions, and it also includes an online store for direct merchandise purchases. Additionally, BabyCenter fosters a community atmosphere with bulletin boards, chat sessions, and Q&A features, allowing expectant mothers and new parents to connect with peers and medical professionals. Recognized for its excellence, BabyCenter won the Best Family and Parenting Site award at the 2006 Webby Awards.

SAND manufactures and sells financial POS machines.

Aveeno provides skin & hair care products made with the most effective ingredients.

MicroMass Communications is a marketing agency specializing in healthcare communications, dedicated to applying evidence-based behavior change strategies to enhance patient health outcomes. Resulting from the merger of SPS and MicroMass, it has become one of the largest independent, full-service healthcare marketing and medical communications agencies in the Southeast. The agency offers a range of services, including patient engagement, relationship marketing, and health behavior consulting, primarily serving pharmaceutical, medical device, and biotechnology companies in the United States. With its unique expertise in human health behavior and healthcare professional advocacy, MicroMass is positioned to create effective, real-world solutions that drive meaningful improvements in patient care.

Gynecare offers an endometrial ablation system for the treatment of uterine disorders. Gynecare offers devices like ThermaChoice Uterine Balloon Therapy system for the treatment of women who experience dysfunctional uterine bleeding. It also offers a VersaPoint Bipolar Electrosurgery system to treat women diagnosed with benign uterine pathologies including fibroids, polyps, adhesions, and divided septa.

Mitek Surgical Products provided bone anchors and minimally invasive surgical tools for orthopedic surgery. The company was founded by three Massachusetts Institute of Technology engineers in 1985.

Menlo Care, Inc. manufactures and markets vascular access and urological devices.