MassVentures

Electrified Thermal Solutions, founded in 2021 and based in Medford, Massachusetts, develops innovative energy storage technology. The company converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks, enabling industrial sectors to replace fossil fuels with zero-carbon heat.

Gel4Med LLC is a Boston-based medical technology company founded in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix that addresses the challenge of antibiotic-resistant bacteria while facilitating tissue regeneration. Utilizing bioinspired and engineering approaches, Gel4Med's technology aims to improve patient outcomes in various therapeutic areas, particularly in wound care and tissue regeneration. Their leading asset features a self-assembling peptide technology that acts as both an antibacterial barrier and a promoter of tissue regeneration, enabling patients to prevent infections during surgical procedures.

Theromics Inc., founded in 2016, develops innovative cell therapies. It specializes in HeatSYNC Gel, a biopolymer thermal accelerant that enhances microwave and radiofrequency energy absorption during soft tissue ablation procedures. This gel amplifies heat movement, optimizes ablation zone shape, increases treatment area, and protects critical tissues.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Electrified Thermal Solutions, founded in 2021 and based in Medford, Massachusetts, develops innovative energy storage technology. The company converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks, enabling industrial sectors to replace fossil fuels with zero-carbon heat.

Bloomer Tech is a company that designs and manufactures bras embedded with advanced fabric engineering technology to monitor women's cardiovascular health. Founded in 2015 and based in Cambridge, Massachusetts, the company utilizes everyday fabrics and machine learning to collect critical health metrics, including electrocardiograms, pulse rates, respiratory rates, and heart rhythms. By integrating biometric sensors into its products, Bloomer Tech aims to create a reliable data set that enhances understanding of women's heart health and supports personalized healthcare solutions. The company's innovative approach enables real-time access to meaningful health data for users and healthcare professionals, facilitating improved monitoring and treatment of chronic diseases. The founders of Bloomer Tech, Aceil Halaby, Alicia Chong Rodriguez, and Monica Abarca, are committed to addressing global cardiovascular health challenges through their technology.

Stata DX develops disease management eRapid technology that enables at-home patient monitoring in clinical studies by implementing custom biomarker panels. The company offers a low-cost, affinity-based electrochemical sensing platform capable of simultaneously detecting a broad range of biomarkers with high sensitivity and selectivity in complex biological fluids, including liquid MRI for the brain, providing real-time information about a system's composition for researchers.

Active Surfaces, a Massachusetts-based company, specializes in commercializing ultra-thin-film solar technology developed at MIT. Its core business involves creating flexible, lightweight solar panels that can be seamlessly integrated into everyday materials and surfaces, revolutionizing the conventional energy sector. The company's innovative manufacturing approach significantly reduces production costs, making solar power more accessible and affordable. This technology presents a transformational opportunity for semiconductor and electronics manufacturing, driving down costs for both module production and installation. By enabling virtually any surface to generate power, Active Surfaces aims to accelerate the transition to a cleaner, more sustainable future.

Western New England University, located in Springfield, Massachusetts, is a small institution known for its close-knit academic environment, where students can build meaningful relationships with faculty and peers. The university offers a range of undergraduate and graduate programs, with particular strengths in Pharmacy, Engineering, and Law. Its undergraduate offerings include disciplines from the Arts and Sciences, Business, and Engineering departments, along with a Pre-Pharmacy major that leads to its highly regarded graduate Pharmaceutical Sciences program. The campus life is vibrant, featuring a variety of cultural events and activities, such as music festivals and seasonal celebrations, fostering community engagement. Students can participate in performing arts groups, a school newspaper, and literary publications, in addition to enjoying organized campus gatherings and regional trips. Admission to undergraduate programs requires the submission of standardized applications, while graduate program applicants must meet specific departmental criteria. Scholarships and financial aid options are available, contributing to accessibility for prospective students.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Gel4Med LLC is a Boston-based medical technology company founded in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix that addresses the challenge of antibiotic-resistant bacteria while facilitating tissue regeneration. Utilizing bioinspired and engineering approaches, Gel4Med's technology aims to improve patient outcomes in various therapeutic areas, particularly in wound care and tissue regeneration. Their leading asset features a self-assembling peptide technology that acts as both an antibacterial barrier and a promoter of tissue regeneration, enabling patients to prevent infections during surgical procedures.

Founded in Boston in 1995, AmberGen specializes in innovative photonic technology for therapeutics and diagnostics. The company's core expertise lies in proteomics and light-based control of biomolecules, aiming to advance medical research and diagnosis through high-resolution, multiplexed analysis of biomarkers.

Founded in 2017 and headquartered in Boston, Southie Autonomy develops robot software that enables industrial robots to be repurposed and redeployed by users without specialized skills. Its system aims to reduce time, cost, and skill barriers for applications like kitting, palletizing, and simple assembly.

Founded in 2020, Irradiant Technologies specializes in developing advanced lithography techniques for high-throughput microfabrication. Headquartered in Cambridge, Massachusetts, the company's core technology enables ultrafast three-dimensional assembly of diverse materials with nanoscale precision, facilitating innovation in photonic and optical components for telecommunications, computation, and sensing.

Northeastern University, founded in 1898, is a private, research-intensive university located in Boston, Massachusetts. It offers a wide range of undergraduate and graduate programs, including doctorate degrees, across nine colleges and schools. Additionally, it provides select advanced degrees at graduate campuses in Charlotte, North Carolina, and Seattle. The university is renowned for its experiential learning approach, integrating real-world experience into its academic curriculum.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Founded in 2021, Z-Polymers is a clean-tech materials science company based in Lowell, Massachusetts. It specializes in developing thin fiber polymers to address fundamental challenges in critical industries such as 3D printing and the hydrogen economy, aiming to replace toxic substances with sustainable alternatives.

Electrified Thermal Solutions, founded in 2021 and based in Medford, Massachusetts, develops innovative energy storage technology. The company converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks, enabling industrial sectors to replace fossil fuels with zero-carbon heat.

The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

InGel Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021. The company focuses on developing engineered cell therapies aimed at targeting neuroprotective pathways to address retinal degeneration. Utilizing stem cells and their secretome, InGel Therapeutics aims to provide neuroprotection for blinding diseases such as retinitis pigmentosa and macular degeneration. The company leverages biodegradable polymers to isolate neuroprotective proteins, initially testing these solutions in vitro before advancing to in vivo applications. Through its innovative approach, InGel Therapeutics seeks to enable healthcare professionals to more effectively treat patients suffering from retinal degeneration.

Jetcool Technologies Inc., established in 2019 and headquartered in Littleton, Massachusetts, specializes in the research and development of advanced chip cooling solutions. The company offers a range of cooling products, from bare die to system level, and provides customized solutions. Jetcool's innovative microjet cooling modules, developed at MIT Lincoln Laboratory, are designed to efficiently cool high-power electronics in industries such as defense and aerospace, advanced semiconductors, data centers, and electric vehicle power systems. The company's technology, published in several academic papers, uses small jets of fluid to cool components at the chip or device scale, enabling manufacturers to create more durable, energy-efficient products.

Harmony is a biotechnology startup that creates human breast milk protein-based infant nutrition designed to help human babies thrive. It is the world’s first dairy-free, allergen-free and environmentally friendly infant nutrition. Harmony Baby Nutrition was established in 2018 and is based in Boston, MA.

Leuko Labs, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in the development of healthcare equipment. The company's primary product, PointCheck, is a non-invasive device designed to monitor and count white blood cells. This innovative technology allows for more frequent testing of immunosuppressed patients, such as those undergoing chemotherapy, enhancing their quality of life and clinical outcomes. The device is particularly beneficial as it eliminates the need for invasive blood draws and laboratory infrastructure, making it more accessible and convenient for patients.

Founded in Boston in 1995, AmberGen specializes in innovative photonic technology for therapeutics and diagnostics. The company's core expertise lies in proteomics and light-based control of biomolecules, aiming to advance medical research and diagnosis through high-resolution, multiplexed analysis of biomarkers.

Leuko Labs, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in the development of healthcare equipment. The company's primary product, PointCheck, is a non-invasive device designed to monitor and count white blood cells. This innovative technology allows for more frequent testing of immunosuppressed patients, such as those undergoing chemotherapy, enhancing their quality of life and clinical outcomes. The device is particularly beneficial as it eliminates the need for invasive blood draws and laboratory infrastructure, making it more accessible and convenient for patients.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

SilarTek is a technology company established in 2020 and located in Leominster, Massachusetts. The company specializes in developing innovative solar silicon technology aimed at making solar panels more affordable and accessible to a broader audience. SilarTek's unique approach involves utilizing molten salt electrolysis combined with an advanced molten salt composition, which enables the production of low-cost solar-grade silicon. This technology is designed to benefit both consumers and businesses by providing an efficient solution for solar panel manufacturing.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Western New England University, located in Springfield, Massachusetts, is a small institution known for its close-knit academic environment, where students can build meaningful relationships with faculty and peers. The university offers a range of undergraduate and graduate programs, with particular strengths in Pharmacy, Engineering, and Law. Its undergraduate offerings include disciplines from the Arts and Sciences, Business, and Engineering departments, along with a Pre-Pharmacy major that leads to its highly regarded graduate Pharmaceutical Sciences program. The campus life is vibrant, featuring a variety of cultural events and activities, such as music festivals and seasonal celebrations, fostering community engagement. Students can participate in performing arts groups, a school newspaper, and literary publications, in addition to enjoying organized campus gatherings and regional trips. Admission to undergraduate programs requires the submission of standardized applications, while graduate program applicants must meet specific departmental criteria. Scholarships and financial aid options are available, contributing to accessibility for prospective students.

Founded in 2017, Paerpay enables merchants nationwide to accept contactless payments without altering existing point-of-sale systems or requiring customers to download an app.

Stata DX develops disease management eRapid technology that enables at-home patient monitoring in clinical studies by implementing custom biomarker panels. The company offers a low-cost, affinity-based electrochemical sensing platform capable of simultaneously detecting a broad range of biomarkers with high sensitivity and selectivity in complex biological fluids, including liquid MRI for the brain, providing real-time information about a system's composition for researchers.

Tufts University is a moderately sized institution that integrates the characteristics of a research university with those of a liberal arts college, fostering an environment of curiosity and creativity. Established with a commitment to student-centered education, Tufts emphasizes the creation and application of knowledge across a diverse range of disciplines. The university offers various programs, including degrees in public health and health informatics through its School of Medicine, and is home to the Tufts Center for the Study of Drug Development, an independent nonprofit organization that enhances the quality and efficiency of pharmaceutical development. Tufts aims to provide transformational experiences for students and faculty in an inclusive and collaborative setting, encouraging innovative thinking and active engagement in addressing complex global challenges.

GenH is a Boston-based company founded in 2017 that specializes in advanced hydroelectric technologies for urban environments. The company focuses on developing modular hydropower systems that enhance and optimize energy generation at non-powered dams and canal heads. By providing resilient and deployable hydropower solutions, GenH enables clients to electrify these sites without the need for significant construction or investment in fixed infrastructure. This innovative approach aims to help clients achieve economic parity with traditional fossil fuel systems, thereby promoting sustainable energy generation while minimizing reliance on subsidies.

Inkbit Corporation, founded in 2017 and based in Medford, Massachusetts, specializes in the research, development, and manufacturing of advanced 3D printers. The company has created a next-generation additive manufacturing platform that integrates machine vision and multi-material jetting technologies. By leveraging expertise from MIT-trained scientists and engineers, Inkbit aims to address the challenges of mass-market additive manufacturing. Its innovative approach enables rapid, on-demand production of polymer 3D printed parts, effectively bridging the gap between prototyping and full-scale manufacturing. This capability caters to the needs of industries requiring high precision and speed for complex, multi-material end-use products.

Boston Engineering delivers innovative and timely solutions by utilizing its Total System Responsibility™ (TSR) philosophy to meet demanding market needs. Through interdisciplinary teams, best practice strategies and seamless integration with client processes, Boston Engineering offers a complete solution that is both flexible and focused.

Realtime Robotics, Inc. is a Boston-based company founded in 2016 that specializes in developing motion planning and control technologies for robots and autonomous vehicles. The company offers a collision-free motion planning platform that allows robots to react instantaneously to their surroundings, enabling safe operation in unstructured environments. Their RapidPlan processor integrates advanced software and hardware, allowing for the generation of safe motion plans in milliseconds, effectively eliminating the trade-off between speed and safety in automation. By facilitating seamless interaction with both static and dynamic objects, Realtime Robotics enhances the capabilities of robots in various applications, including industrial automation and autonomous vehicles, thereby promoting broader adoption and integration of robotics technology in everyday operations.

PlenOptika, Inc. is a technology company based in Allston, Massachusetts, that specializes in the development of a handheld device called QuickSee, which provides accurate eyeglass prescriptions through precise refractive measurements. Founded in 2014 as a spin-off from the Massachusetts Institute of Technology, the company addresses the significant global issue of low vision affecting over one billion people. QuickSee is designed to facilitate optometry, especially in rural and resource-limited settings, by simplifying the process of vision correction. The device captures the eye's full aberration fingerprint, effectively reducing the costs and physical space required by traditional autorefractors. PlenOptika aims to make eye care accessible to underserved communities worldwide and has received recognition from various social innovation foundations and business competitions for its contributions to healthcare technology.

Founded in 2017, Infinite Cooling specializes in wastewater management and recycling. It uses high-voltage electric fields to capture and recycle vast amounts of water that would otherwise be lost at industrial facilities like power plants, data centers, and factories.

DynamiCare Health offers a digital platform that assists individuals in monitoring and reducing their use of drugs, opioids, alcohol, and tobacco. The platform enables users to perform substance tests via an app and tracks treatment attendance using GPS. Healthcare providers can access data on participants' progress through the DynamicCare Analytics portal, which sends real-time risk alerts when clients are at risk.

Leuko Labs, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in the development of healthcare equipment. The company's primary product, PointCheck, is a non-invasive device designed to monitor and count white blood cells. This innovative technology allows for more frequent testing of immunosuppressed patients, such as those undergoing chemotherapy, enhancing their quality of life and clinical outcomes. The device is particularly beneficial as it eliminates the need for invasive blood draws and laboratory infrastructure, making it more accessible and convenient for patients.

NanoView Diagnostics develops the ExoView platform for characterizing extracellular vesicles through specific binding and detection on an affinity microarray. Its products include ExoView R100, ExoView Tetraspanin kits, custom assays, sample services, and support.

Metalmark Innovations, Inc. focuses on developing and delivering advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, enhancing indoor air quality. The company offers its innovative materials as additive coatings for various applications, including building materials and vehicle interiors, effectively addressing pollutants such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs. Its air cleaning technology employs catalytic materials that filter air with nanoscale precision, contributing to solutions for air pollution and climate change challenges. Founded in 2017 and headquartered in Boston, Massachusetts, Metalmark Innovations was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Jetcool Technologies Inc., established in 2019 and headquartered in Littleton, Massachusetts, specializes in the research and development of advanced chip cooling solutions. The company offers a range of cooling products, from bare die to system level, and provides customized solutions. Jetcool's innovative microjet cooling modules, developed at MIT Lincoln Laboratory, are designed to efficiently cool high-power electronics in industries such as defense and aerospace, advanced semiconductors, data centers, and electric vehicle power systems. The company's technology, published in several academic papers, uses small jets of fluid to cool components at the chip or device scale, enabling manufacturers to create more durable, energy-efficient products.

InstantEye Robotics is a division of Physical Sciences Inc., both located in Andover Massachusetts, approximately a half-hour north of Boston. InstantEye Robotics’ tactical, unmanned aerial systems (UAS) are the systems of choice by the military, law enforcement, first responder, and commercial users around the world. Our products are characterized by their affordability, ruggedness, and ease of use. We provide full-spectrum solutions, from initial concepts through to products manufactured in our state-of-the-art production facility.

ClearGov Inc. is a financial transparency and budgeting platform dedicated to local governments and their residents, primarily serving communities in California, Connecticut, Massachusetts, and New York. Founded in 2015 and headquartered in Maynard, Massachusetts, ClearGov develops a Software-as-a-Service platform that transforms complex financial statements into interactive infographics. Its offerings include modules for financial forecasting, peer-to-peer financial benchmarking, collaborative budgeting, and enhanced public accountability. The platform is designed to streamline the budget process by automating workflows, increasing collaboration, and centralizing data, making it accessible and effective for local governments of all sizes. ClearGov's solutions empower municipalities to compare their spending with similar communities, fostering better decision-making and transparency. The company has gained recognition in the GovTech sector and has been acknowledged for its innovative culture and workplace environment.

Unstack Inc. is a technology company based in Cambridge, Massachusetts, that specializes in a no-code platform designed for building websites, landing pages, and blogs specifically for SaaS, eCommerce brands, and marketing teams. Established in 2019, Unstack provides a unified marketing solution that enables marketers and entrepreneurs to grow their businesses without requiring technical expertise in coding or design. The platform allows users to create high-performance digital assets that drive traffic, generate leads, and enhance sales, facilitating a seamless approach to online marketing and customer engagement. By focusing on ease of use and collaboration, Unstack aims to empower clients to effectively publish and manage their web presence, thereby supporting their growth initiatives.

Harvard Management Company is the investment arm of Harvard University, responsible for managing the university’s endowment and related financial assets. Based in Boston and founded in 1974, the organization oversees a globally diversified portfolio that includes public equity and fixed income investments as well as allocations to private equity, venture capital, and real estate. It also works with external managers to oversee portions of its portfolios, with the aim of generating long-term returns to support Harvard’s teaching, research, and financial aid initiatives.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Northeastern University, founded in 1898, is a private, research-intensive university located in Boston, Massachusetts. It offers a wide range of undergraduate and graduate programs, including doctorate degrees, across nine colleges and schools. Additionally, it provides select advanced degrees at graduate campuses in Charlotte, North Carolina, and Seattle. The university is renowned for its experiential learning approach, integrating real-world experience into its academic curriculum.

Boston Engineering delivers innovative and timely solutions by utilizing its Total System Responsibility™ (TSR) philosophy to meet demanding market needs. Through interdisciplinary teams, best practice strategies and seamless integration with client processes, Boston Engineering offers a complete solution that is both flexible and focused.

Physical Sciences Inc., founded in 1973 and headquartered in Andover, Massachusetts, provides contract research and development services across a wide range of technical areas for both government and commercial clients. The company specializes in advanced imaging and sensing technologies, offering products such as adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, Physical Sciences develops and supplies various analytical technology sensors, mass flux monitors, and laser-based detection systems. The company's engineering services include system engineering, instrument testing and calibration, and the development of electrochemical engineering solutions. It serves diverse markets, including aerospace, energy, biomedical, defense, and telecommunications, through direct sales, strategic partnerships, and licensing agreements both domestically and internationally. With satellite offices in California, Maryland, Ohio, and Massachusetts, as well as a subsidiary in New Jersey, Physical Sciences leverages its extensive expertise to address complex challenges in multiple industries.

Lambent is a Boston-based software company that provides an AI-powered platform for facilities management and space planning, leveraging existing data sources such as Wi-Fi to deliver occupancy analytics and utilization insights that enable corporate and higher education campuses to make data-driven decisions about workplace use, planning, scheduling, and maintenance while offering an alternative to sensor deployments and helping organizations reduce costs and optimize space and operations.

Labviva operates a digital marketplace connecting life science researchers with suppliers of reagents, chemicals, and lab equipment. It offers over 10 million products, simplifying procurement through real-time inventory tracking, AI-driven purchase automation, and forecasting.

Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.

MachineMetrics Inc. is a company that specializes in developing real-time production monitoring software for various manufacturing sectors, including aerospace, automotive, and medical devices. Founded in 2014 and headquartered in Northampton, Massachusetts, the company offers an automated cloud solution that collects, analyzes, and visualizes machine data. This platform provides manufacturers with real-time dashboards and notifications, enabling them to address production issues promptly and make informed decisions. By simplifying the integration of Internet of Things (IoT) technology on the shop floor, MachineMetrics enhances manufacturing efficiency, reportedly improving performance by over 20% for its clients. The company's focus on delivering deep analytics and predictive insights allows clients to digitize legacy processes and maximize profitability.

Alloy Enterprises is a Somerville, Massachusetts-based developer of 3D printing technologies and industrial-engineered products aimed at reducing inefficiencies in conventional manufacturing. The company has developed an aluminum additive technology that enables dense, low-cost parts without relying on expensive or hazardous powders, addressing limitations in traditional methods and supporting advances in lightweight components and emissions reduction.

NanoView Diagnostics develops the ExoView platform for characterizing extracellular vesicles through specific binding and detection on an affinity microarray. Its products include ExoView R100, ExoView Tetraspanin kits, custom assays, sample services, and support.

Physical Sciences Inc., founded in 1973 and headquartered in Andover, Massachusetts, provides contract research and development services across a wide range of technical areas for both government and commercial clients. The company specializes in advanced imaging and sensing technologies, offering products such as adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, Physical Sciences develops and supplies various analytical technology sensors, mass flux monitors, and laser-based detection systems. The company's engineering services include system engineering, instrument testing and calibration, and the development of electrochemical engineering solutions. It serves diverse markets, including aerospace, energy, biomedical, defense, and telecommunications, through direct sales, strategic partnerships, and licensing agreements both domestically and internationally. With satellite offices in California, Maryland, Ohio, and Massachusetts, as well as a subsidiary in New Jersey, Physical Sciences leverages its extensive expertise to address complex challenges in multiple industries.

MSW Power Corporation specializes in manufacturing innovative waste management solutions. Founded in 2012 and headquartered in Acton, Massachusetts, the company offers a range of products designed to convert various types of waste, including paper, wood, plastic, agricultural waste, and food, into usable energy in the form of electricity and heat. Key products include the BWEC GEM, an integrated system for waste conversion, and HydroPactor, which reduces the weight of waste by removing moisture. Additionally, MSW Power features a solid waste destruction system that employs mechanical and thermal processes to eliminate moisture from solid waste. The company is committed to providing environmentally beneficial and economically viable solutions that address energy and environmental challenges.

Blue Therapeutics is a drug discovery and development technology company based in Waltham, Massachusetts, founded in 2015 by Ajay Yekkirala, David Roberson, Michio Painter, and academic founder Phil Portoghese. The company aims to translate decades of academic research into therapeutic solutions that improve patient outcomes in pain management by delivering novel therapies with better efficacy and fewer adverse effects. It uses a receptor-interactomics approach, a new dimension of disease biology, to develop therapeutics that overcome the limitations of traditional pharmacology and pursue safer, more effective treatments across pain-related indications.

Realtime Robotics, Inc. is a Boston-based company founded in 2016 that specializes in developing motion planning and control technologies for robots and autonomous vehicles. The company offers a collision-free motion planning platform that allows robots to react instantaneously to their surroundings, enabling safe operation in unstructured environments. Their RapidPlan processor integrates advanced software and hardware, allowing for the generation of safe motion plans in milliseconds, effectively eliminating the trade-off between speed and safety in automation. By facilitating seamless interaction with both static and dynamic objects, Realtime Robotics enhances the capabilities of robots in various applications, including industrial automation and autonomous vehicles, thereby promoting broader adoption and integration of robotics technology in everyday operations.

PlenOptika, Inc. is a technology company based in Allston, Massachusetts, that specializes in the development of a handheld device called QuickSee, which provides accurate eyeglass prescriptions through precise refractive measurements. Founded in 2014 as a spin-off from the Massachusetts Institute of Technology, the company addresses the significant global issue of low vision affecting over one billion people. QuickSee is designed to facilitate optometry, especially in rural and resource-limited settings, by simplifying the process of vision correction. The device captures the eye's full aberration fingerprint, effectively reducing the costs and physical space required by traditional autorefractors. PlenOptika aims to make eye care accessible to underserved communities worldwide and has received recognition from various social innovation foundations and business competitions for its contributions to healthcare technology.

Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.

C-2 Innovations designs and builds all-weather amphibious robots for monitoring, sampling, and mapping various sea-floor terrains. It specializes in areas including; product development, low volume production, business development consulting, contract R&D, and 3-D Animation. C-2 Innovation was founded in 2007 and is based in Shrewsbury, Massachusetts, USA.

Labviva operates a digital marketplace connecting life science researchers with suppliers of reagents, chemicals, and lab equipment. It offers over 10 million products, simplifying procurement through real-time inventory tracking, AI-driven purchase automation, and forecasting.

Inkbit Corporation, founded in 2017 and based in Medford, Massachusetts, specializes in the research, development, and manufacturing of advanced 3D printers. The company has created a next-generation additive manufacturing platform that integrates machine vision and multi-material jetting technologies. By leveraging expertise from MIT-trained scientists and engineers, Inkbit aims to address the challenges of mass-market additive manufacturing. Its innovative approach enables rapid, on-demand production of polymer 3D printed parts, effectively bridging the gap between prototyping and full-scale manufacturing. This capability caters to the needs of industries requiring high precision and speed for complex, multi-material end-use products.

MachineMetrics Inc. is a company that specializes in developing real-time production monitoring software for various manufacturing sectors, including aerospace, automotive, and medical devices. Founded in 2014 and headquartered in Northampton, Massachusetts, the company offers an automated cloud solution that collects, analyzes, and visualizes machine data. This platform provides manufacturers with real-time dashboards and notifications, enabling them to address production issues promptly and make informed decisions. By simplifying the integration of Internet of Things (IoT) technology on the shop floor, MachineMetrics enhances manufacturing efficiency, reportedly improving performance by over 20% for its clients. The company's focus on delivering deep analytics and predictive insights allows clients to digitize legacy processes and maximize profitability.

Lambent is a Boston-based software company that provides an AI-powered platform for facilities management and space planning, leveraging existing data sources such as Wi-Fi to deliver occupancy analytics and utilization insights that enable corporate and higher education campuses to make data-driven decisions about workplace use, planning, scheduling, and maintenance while offering an alternative to sensor deployments and helping organizations reduce costs and optimize space and operations.

Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.

Dynamo Micropower Corporation is a technology company focused on developing innovative fuel-flexible gas turbines tailored for small distributed generation in the oil and gas industry. Founded in 2011 and headquartered in Somerville, Massachusetts, the company offers advanced power solutions, including its PowerCore system, which provides reliable, grid-quality power while operating on local unrefined gas. This capability allows customers to significantly reduce energy costs, with savings of up to 80%, and enhances equipment performance by up to 25%. Dynamo also provides custom solutions and a flameless turboheater known as Infernocore, addressing the specific needs of oilfield applications. The company distributes its products through a network of distributors and offers support services via service partners, having established a solid customer base that includes notable clients such as Kinder Morgan and Caterpillar.

Horsepower Technologies Inc. is an animal healthcare company specializing in the manufacture of rehabilitative orthotics for horses. Founded in 2008 and headquartered in Lowell, Massachusetts, the company develops innovative products designed to facilitate the safe recovery of injured horses. Its flagship product, FastTrack, features protective padding for shock absorption and durability, a hard shell cuff for musculoskeletal support, and a mechanism to limit the extension of the fetlock joint. The technology aids in redirecting weight-bearing forces away from healing tendons and ligaments, allowing horses to resume moderate exercise safely and effectively. Horsepower Technologies sells its products online, aiming to enhance recovery outcomes for horses experiencing lameness.

Spero Devices, Inc. is an artificial intelligence company founded in 2015 and headquartered in Acton, Massachusetts. The company specializes in developing CMOS-based nanotechnology co-processors designed for mobile devices, focusing on real-time computation while adhering to mobile power budgets. Spero Devices creates hardware accelerators that enhance computational efficiency and are particularly suited for edge applications involving multi-object detection, tracking, and segmentation. Their innovative technology includes custom high-endurance memory cells tailored to meet specific application requirements. By transforming edge data into actionable insights, Spero Devices enables advanced services such as automated selection of AI training data, thereby expanding the potential of artificial intelligence in mobile contexts.

Fairmarkit is a Boston‑based company that offers a SaaS platform for tail spend management. The platform is ERP‑agnostic and automates procurement for small to medium purchases by using machine learning to analyze unstructured spend data. It provides automated request‑for‑quotation workflows, vendor recommendations, price benchmarking, trend analysis, and risk identification. By delivering these capabilities in a single, cloud‑based solution, Fairmarkit helps procurement and supply‑chain teams reduce manual effort, increase competitive bidding, and realize savings across their tail spend.

ClearGov Inc. is a financial transparency and budgeting platform dedicated to local governments and their residents, primarily serving communities in California, Connecticut, Massachusetts, and New York. Founded in 2015 and headquartered in Maynard, Massachusetts, ClearGov develops a Software-as-a-Service platform that transforms complex financial statements into interactive infographics. Its offerings include modules for financial forecasting, peer-to-peer financial benchmarking, collaborative budgeting, and enhanced public accountability. The platform is designed to streamline the budget process by automating workflows, increasing collaboration, and centralizing data, making it accessible and effective for local governments of all sizes. ClearGov's solutions empower municipalities to compare their spending with similar communities, fostering better decision-making and transparency. The company has gained recognition in the GovTech sector and has been acknowledged for its innovative culture and workplace environment.

Metalmark Innovations, Inc. focuses on developing and delivering advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, enhancing indoor air quality. The company offers its innovative materials as additive coatings for various applications, including building materials and vehicle interiors, effectively addressing pollutants such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs. Its air cleaning technology employs catalytic materials that filter air with nanoscale precision, contributing to solutions for air pollution and climate change challenges. Founded in 2017 and headquartered in Boston, Massachusetts, Metalmark Innovations was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Manus Bio recreates plant processes in microorganisms using fermentation technology. This enables the production of natural ingredients such as flavors, fragrances, food ingredients, bio-pesticides, and pharmaceuticals, offering businesses affordable and sustainable solutions.

Physical Sciences Inc., founded in 1973 and headquartered in Andover, Massachusetts, provides contract research and development services across a wide range of technical areas for both government and commercial clients. The company specializes in advanced imaging and sensing technologies, offering products such as adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, Physical Sciences develops and supplies various analytical technology sensors, mass flux monitors, and laser-based detection systems. The company's engineering services include system engineering, instrument testing and calibration, and the development of electrochemical engineering solutions. It serves diverse markets, including aerospace, energy, biomedical, defense, and telecommunications, through direct sales, strategic partnerships, and licensing agreements both domestically and internationally. With satellite offices in California, Maryland, Ohio, and Massachusetts, as well as a subsidiary in New Jersey, Physical Sciences leverages its extensive expertise to address complex challenges in multiple industries.

TelAztec specializes in manufacturing nano-textured optics, serving industries including semiconductors, medical devices, and automotive. Their products include optical filter microstructures for applications like liquid crystal displays, infrared sensors, advanced lithography systems, and passive optical filters.

Solchroma Technologies, Inc. is a manufacturer of innovative digital display screens designed specifically for advertising applications. Founded in 2015 and headquartered in Somerville, Massachusetts, the company specializes in non-LED displays that utilize sunlight-reflective properties and high-quality color capabilities. Their proprietary technology employs electroactive polymer actuators, functioning as hydraulic pumps, to move colored ink into separate filter chambers, allowing for full-color images using ambient light. This approach enables the creation of low-power, high-performance digital signage that complies with zoning regulations where traditional light-emitting technologies are restricted. Solchroma's products are particularly suited for outdoor advertising and on-premise signage, contributing to the development of smart cities while minimizing light pollution.

Horsepower Technologies Inc. is an animal healthcare company specializing in the manufacture of rehabilitative orthotics for horses. Founded in 2008 and headquartered in Lowell, Massachusetts, the company develops innovative products designed to facilitate the safe recovery of injured horses. Its flagship product, FastTrack, features protective padding for shock absorption and durability, a hard shell cuff for musculoskeletal support, and a mechanism to limit the extension of the fetlock joint. The technology aids in redirecting weight-bearing forces away from healing tendons and ligaments, allowing horses to resume moderate exercise safely and effectively. Horsepower Technologies sells its products online, aiming to enhance recovery outcomes for horses experiencing lameness.

Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.

ClearGov Inc. is a financial transparency and budgeting platform dedicated to local governments and their residents, primarily serving communities in California, Connecticut, Massachusetts, and New York. Founded in 2015 and headquartered in Maynard, Massachusetts, ClearGov develops a Software-as-a-Service platform that transforms complex financial statements into interactive infographics. Its offerings include modules for financial forecasting, peer-to-peer financial benchmarking, collaborative budgeting, and enhanced public accountability. The platform is designed to streamline the budget process by automating workflows, increasing collaboration, and centralizing data, making it accessible and effective for local governments of all sizes. ClearGov's solutions empower municipalities to compare their spending with similar communities, fostering better decision-making and transparency. The company has gained recognition in the GovTech sector and has been acknowledged for its innovative culture and workplace environment.

Founded in 2017, Infinite Cooling specializes in wastewater management and recycling. It uses high-voltage electric fields to capture and recycle vast amounts of water that would otherwise be lost at industrial facilities like power plants, data centers, and factories.

Massachusetts Materials Technologies, an MIT spin-off established in 2014 and based in Waltham, Massachusetts, focuses on transforming innovative concepts into commercially viable products in the realms of materials, mechanics, and manufacturing. The company specializes in nondestructive technology for assessing the strength and toughness of materials, particularly for the oil and gas sector. Its advanced instrumentation allows for accurate measurement of the mechanical properties of pipelines without interrupting service or requiring the removal of pipe segments. This capability provides industries with essential insights into the structural integrity of natural gas pipelines, enhancing safety and operational reliability.

Optodot Corporation develops nanotechnology-based components for energy storage, energy conservation, and energy generation markets. Its product suite includes NanoPore, a ceramic nano-porous separator produced through a patented coating-based process, and NPORE lithium-ion battery separators, along with infrared-coated films and laminates used in covert and forensic security applications and window films. The company focuses on lithium-ion battery separators and organic solar cell markets, and on optical communications technologies such as optical switches, buffers, modulators, and photodetectors built on optical chip and component technology to improve optical transport networks. Optodot also offers intellectual property, product development, and contract coating services and pursues strategic partnerships and licensing to commercialize products for energy, security, and communications solutions. Its customers include startups and large enterprises, as well as government agencies like the Department of Defense and the Department of Energy. The company has a strategic partnership with Madico, Inc. since its operations began in 2000 and is headquartered in Woburn, Massachusetts.

Spero Devices, Inc. is an artificial intelligence company founded in 2015 and headquartered in Acton, Massachusetts. The company specializes in developing CMOS-based nanotechnology co-processors designed for mobile devices, focusing on real-time computation while adhering to mobile power budgets. Spero Devices creates hardware accelerators that enhance computational efficiency and are particularly suited for edge applications involving multi-object detection, tracking, and segmentation. Their innovative technology includes custom high-endurance memory cells tailored to meet specific application requirements. By transforming edge data into actionable insights, Spero Devices enables advanced services such as automated selection of AI training data, thereby expanding the potential of artificial intelligence in mobile contexts.

MachineMetrics Inc. is a company that specializes in developing real-time production monitoring software for various manufacturing sectors, including aerospace, automotive, and medical devices. Founded in 2014 and headquartered in Northampton, Massachusetts, the company offers an automated cloud solution that collects, analyzes, and visualizes machine data. This platform provides manufacturers with real-time dashboards and notifications, enabling them to address production issues promptly and make informed decisions. By simplifying the integration of Internet of Things (IoT) technology on the shop floor, MachineMetrics enhances manufacturing efficiency, reportedly improving performance by over 20% for its clients. The company's focus on delivering deep analytics and predictive insights allows clients to digitize legacy processes and maximize profitability.

Applause specializes in crowd-sourced digital quality testing, empowering companies worldwide to deliver flawless digital experiences across websites, mobile apps, IoT devices, and in-store experiences. With over 300,000 testers globally, Applause offers comprehensive testing services that enhance product quality, accelerate time-to-market, and improve customer satisfaction.

Poly6 Technologies, Inc. is a Boston-based company that specializes in digital manufacturing solutions for the biotechnology, aerospace, and electronics industries. Established in 2016 and emerging from MIT's Langer Lab, Poly6 develops innovative stimuli-responsive materials systems that facilitate the integration of hardware, software, and materials within existing production processes. Utilizing advanced 3D printing technology, the company focuses on creating intelligent materials that enhance engineering design capabilities and improve system efficiency. Poly6's solutions allow for the production of complex components with better tolerance control, significantly reducing costs in established manufacturing sectors by up to 30%. Additionally, the company is committed to environmental sustainability, having developed a novel bioplastic from citrus waste, which aims to mitigate pollution in manufacturing practices.

Heila Technologies, Inc. is a Massachusetts-based company that specializes in the development of a platform designed to integrate and optimize distributed energy resources (DERs) such as solar arrays and batteries. The Heila Platform employs a decentralized optimization system that simplifies the management of these resources, enabling the creation of self-managing microgrids. By transforming individual nodes within the energy system into intelligent agents, the platform facilitates autonomous coordination and optimization of power assets. This approach helps to reduce complexity and costs while enhancing resilience and efficiency in energy operations. Heila Technologies serves a diverse clientele, including partners, utility representatives, developers, energy users, and public officials. Originally founded as Heila Technologies LLC, the company was incorporated in 2015 and has its roots in MIT.

Via Separations, Inc. is a company that specializes in developing membrane-based products for the separation of industrial liquids, aimed at enhancing efficiency in challenging industrial environments. Founded in 2016 and based in Somerville, Massachusetts, the company focuses on industrial decarbonization through innovative chemistries that significantly reduce energy consumption in manufacturing processes. Via's technology allows facilities to cut energy usage by 90% during chemical separation, replacing traditional heat-based methods with a highly selective and robust membrane filtration system. This advancement not only helps to minimize the environmental impact of industrial processes, but it also creates additional revenue opportunities for customers. Currently, Via is conducting pilot trials at pulp and paper facilities with the goal of eliminating 100 million metric tons of CO2 emissions by 2050. The company has successfully scaled its technology and demonstrated working prototypes at a commercial level, having emerged from MIT's Department of Material Science & Engineering.

BoardOnTrack provides expertise, training, powerful, web-based tools, and a membership community to the foot soldiers in the battle to improve our nation's public school system. The charter school is a multi-million dollar public enterprise. Running it with a group of volunteers is a daunting task. BoardOnTrack helps in leveraging the efforts of volunteer board members into real results: academic excellence and organizational sustainability. It was founded in 2010 and is headquartered in Concord, Massachusetts.

Modular Genetics designs and develops engineered microorganisms that synthesize chemicals from renewable raw materials, such as sugar. The company uses an automated gene engineering system to create new products, with a focus on sustainable chemistry. It aims to accelerate product development, reduce costs, and enable simultaneous development of multiple products. Founded in 2000 and based in Woburn, Massachusetts.

Grapevine Logic, Inc. is an influencer marketing platform that connects brands and agencies with YouTube content creators for effective promotional campaigns. Established in 2011 and headquartered in Boston, Massachusetts, the company facilitates direct links between creators and pre-qualified brands seeking sponsorships. Grapevine Logic offers a comprehensive booking and analytics platform, allowing marketers to collaborate with creators, track campaign performance, and monitor various metrics such as sales and engagement. Additionally, the platform includes a dashboard where brands and agencies can submit creative briefs and receive pitches from creators interested in promoting their products or services. With a network of over 177,000 creators generating more than 6 billion monthly views, Grapevine Logic serves as a vital resource for brands looking to leverage influencer marketing. The company previously operated under the name Moving Metrics, Inc., and is currently a subsidiary of Seven Stars Cloud Group, Inc.

Boston Engineering delivers innovative and timely solutions by utilizing its Total System Responsibility™ (TSR) philosophy to meet demanding market needs. Through interdisciplinary teams, best practice strategies and seamless integration with client processes, Boston Engineering offers a complete solution that is both flexible and focused.

Kuva Systems develops an industrial IoT solution that continuously monitors and quantifies methane and VOC emissions with an infrared imaging system. The technology automatically detects leaks, measures emission levels, and provides operators with annotated video clips, while visualizing events in day or day-night modes and transmitting quantified visuals to the cloud in real time, enabling oil and gas operators to monitor assets more cost-effectively. Founded in 2015 and headquartered in Cambridge, Massachusetts, Kuva Systems focuses on enabling safer, more efficient emissions surveillance for industrial facilities.

Evaptainers develops electricity-free mobile refrigeration units that utilize evaporative cooling technology. Founded in 2014, the company aims to improve produce shelf-life along the supply chain, particularly in developing countries.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Jebbit, Inc. is a Boston-based company that specializes in providing interactive mobile solutions for marketers and digital sales teams. Founded in 2011, Jebbit operates a declared data platform that allows brands to create personalized mobile experiences aimed at capturing essential consumer data. By enabling the development of engaging content such as quizzes, lookbooks, and virtual tours, Jebbit helps enterprises gather insights into consumer intentions, motivations, and preferences, moving away from reliance on inaccurate third-party data. The company serves various industries, including travel, e-commerce, and sports, with notable clients like Cathay Pacific Airways and LifeLock. Jebbit's innovative approach to mobile marketing has earned it recognition, including being named one of the Top 25 Most Promising Companies by CNBC and receiving accolades for its tech culture.

Barrett Technology, LLC, established in 1990 and located in Newton, Massachusetts, specializes in the design and manufacture of advanced robotic manipulators. The company has pioneered technology that enhances flexibility in articulated arms and hands, positioning itself as a leader in this field. Renowned for its innovative solutions, Barrett Technology earned recognition in the Guinness Book of World Records for its advanced manipulator technology. The company offers a high degree of versatility, catering to a wide range of applications across various industries.