MassVentures is a venture capital firm based in Waltham, Massachusetts, established in 1978 as a quasi-public corporation by the Massachusetts Legislature. The firm focuses on providing seed and early-stage funding to high-growth startups, facilitating their transition from concept to commercialization. MassVentures invests primarily in sectors such as information technology, healthcare, cybersecurity, e-commerce, mobile, manufacturing, and robotics. With a governance structure that includes an independent Board of Directors and management by experienced venture capitalists, MassVentures leverages the state's entrepreneurial spirit and innovation centers to support the Massachusetts innovation economy. The firm also offers accelerator programs to further assist emerging companies in their growth journey.
AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.
Versatope Therapeutics
Grant in 2024
Versatope Therapeutics is a preclinical-stage biotechnology company specializing in immunotherapy. The company has developed a unique bacterial factory nanoparticle technology that allows for the display of multiple epitopes, addressing the challenges of strain-specific immunity. This innovative approach aims to enhance vaccine potency and improve therapeutic delivery. By enabling the creation of a single vaccine capable of protecting against multiple strains of influenza, Versatope seeks to provide solutions that can significantly advance vaccine development for biotechnology companies.
Advanced Silicon Group
Grant in 2024
Advanced Silicon Group is a nanotechnology company established in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, offering a range of technologies that include photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). By leveraging silicon nanowire arrays, Advanced Silicon Group aims to enhance the performance of its clients' products while reducing costs, particularly through the development of next-generation biosensors that enable the simultaneous measurement of multiple protein concentrations.
Guardion
Grant in 2024
Guardion specializes in advanced sensor technology aimed at enhancing safety and security through innovative detection systems. The company has developed the world's first radiation detector that leverages the unique quantum properties of nanomaterials, resulting in low-cost, sensitive, and energy-efficient devices suitable for widespread deployment. Guardion's products include analytical instruments and portable chemical and radiation detectors, designed for use in challenging environments across various sectors, including aerospace, medical, and national security. Recognized for its contributions to technology and innovation, Guardion received the MassChallenge 2017 Gold Prize and the Technology in Space Prize from the Center for Advancement in Science in Space and Boeing. In early 2018, the company was selected for the inaugural cohort of the Techstars Autonomous Tech Accelerator, sponsored by the Air Force.
AeroShield
Convertible Note in 2023
AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.
Advanced Silicon Group
Grant in 2023
Advanced Silicon Group is a nanotechnology company established in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, offering a range of technologies that include photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). By leveraging silicon nanowire arrays, Advanced Silicon Group aims to enhance the performance of its clients' products while reducing costs, particularly through the development of next-generation biosensors that enable the simultaneous measurement of multiple protein concentrations.
Irradiant Technologies
Grant in 2023
Irradiant Technologies, founded in 2020 and based in Cambridge, Massachusetts, specializes in advanced nanofabrication utilizing implosion fabrication lithography. The company focuses on developing a platform that facilitates the ultrafast three-dimensional assembly of mixed materials, such as conductors, semiconductors, dielectrics, proteins, and DNA, with nanoscale precision and gradient control. This innovative approach enables the creation of novel photonic and optical components, providing light-based alternatives for applications in telecommunications, computation, and sensing.
AeroShield
Grant in 2023
AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.
AeroShield
Grant in 2022
AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.
AeroShield
Seed Round in 2022
AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.
Metalmark Innovations
Grant in 2021
Metalmark Innovations, Inc. develops advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, thereby enhancing indoor air quality. The company offers its innovative materials as coating additives for various applications, including building materials and vehicle interiors. Its technology effectively targets and breaks down harmful substances such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs in diverse transportation settings, including airplanes, ships, trains, cars, and buses. Founded in 2017 and based in Boston, Massachusetts, Metalmark Innovations aims to address the pressing challenges of air pollution and climate change through its cutting-edge air cleaning solutions. The company was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.
Physical Sciences
Grant in 2020
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
Physical Sciences
Grant in 2020
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
MicroContinuum
Grant in 2019
MicroContinuum offers precision micro-and nano-imprinting and patterning using patented roll-to-roll and batch manufacturing technologies. It y serves a range of clients, including Fortune 100 corporations, startups, and government labs, helping test and develop new nanostructured surfaces for the electronics, lighting, solar, energy harvesting, and health industries.
Uniqarta
Grant in 2018
Uniqarta specializes in the development of advanced technologies for manufacturing small, ultra-thin integrated circuits (ICs) that can be embedded into everyday materials like paper and plastic. By creating Smart Materials, the company eliminates the need for additional RFID labels, facilitating the advancement of the Internet of Things (IoT). Uniqarta's innovative approach employs laser-enabled assembly techniques, which replace traditional pick-and-place methods with a faster, more efficient massively parallel laser process. This technology addresses integration challenges associated with ultra-thin ICs, allowing electronics manufacturers to produce next-generation products effectively.
ZwitterCo
Grant in 2018
ZwitterCo specializes in advanced membrane solutions for the treatment of highly impaired wastewater, focusing on the development of reverse osmosis and nanofiltration technologies. These innovations enable the effective reuse and recycling of water resources by addressing challenges such as fouling and chemical demands. ZwitterCo's membranes are designed to treat historically unfilterable streams, allowing customers to transform waste into a valuable resource. With features such as chlorine tolerance and resistance to irreversible fouling, the company's technology supports steady performance and durability, making wastewater treatment economically viable for industrial applications.
Metalmark Innovations
Grant in 2018
Metalmark Innovations, Inc. develops advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, thereby enhancing indoor air quality. The company offers its innovative materials as coating additives for various applications, including building materials and vehicle interiors. Its technology effectively targets and breaks down harmful substances such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs in diverse transportation settings, including airplanes, ships, trains, cars, and buses. Founded in 2017 and based in Boston, Massachusetts, Metalmark Innovations aims to address the pressing challenges of air pollution and climate change through its cutting-edge air cleaning solutions. The company was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.
Physical Sciences
Grant in 2018
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
Optodot
Grant in 2017
Optodot Corporation specializes in developing nanotechnology-based components for energy storage, conservation, and generation markets. The company offers a range of products, including NanoPore, a separator made from nano porous ceramic membranes, and NPORE lithium-ion battery separators. Additionally, it provides infrared coated films and laminates for covert and forensic security applications, along with window films. Optodot is focused on advancing technologies for lithium-ion batteries and organic solar cells, as well as optical communications, which involve optical switches, buffers, modulators, and photo detectors. The company also offers intellectual property, product development, and contract services related to coatings, and actively pursues strategic partnerships and licensing opportunities to commercialize its innovations. Its clientele includes start-ups, major corporations, and government entities such as the Department of Defense and the Department of Energy. Founded in 2000 and based in Woburn, Massachusetts, Optodot is committed to continual innovation in the field of nanoporous membranes.
AddiLat
Grant in 2015
AddiLat is a company focused on developing advanced electronics process technology, specifically in the realm of nano-particle printed electronics. This innovative technology facilitates the manufacturing of touchscreen sensors that offer superior optical performance while also being cost-effective. By streamlining the production of transparent conducting films, AddiLat's process eliminates several processing steps, resulting in significant savings in production costs and reduced development and lead times for manufacturers.
Physical Sciences
Grant in 2015
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
Xtalic
Grant in 2014
Xtalic Corporation, founded in 2005 and based in Marlborough, Massachusetts, specializes in developing and manufacturing advanced metal coatings for various applications, primarily in the electronics sector. The company offers innovative nanostructured coatings that enhance corrosion and wear resistance while providing exceptional aesthetics. Notable products include XTRONIC, a barrier layer designed to improve durability, and LUNA, which serves as a gold replacement for electrical connectors. Xtalic's electroplating process is environmentally friendly, eliminating the use of hexavalent chromium, thereby reducing compliance costs and safety risks for workers. By enabling clients to decrease reliance on expensive raw materials and replace hazardous substances, Xtalic contributes to more sustainable manufacturing practices in both decorative and functional metal finishing.
Eascra Biotech
Eascra Biotech specializes in developing DNA-inspired, Janus base nanomaterials for targeted drug delivery. Their platform, based on three generations of DNA nanotubes, is designed to effectively penetrate and treat hard-to-reach tissues like articular cartilage, the central nervous system, and solid tumors. These nanomaterials can encapsulate and stabilize various therapeutic agents, including mRNA, siRNA, proteins, and gene-editing tools, at room temperature, enhancing their efficacy and reducing systemic exposure.
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