New Enterprise Associates

Chaos Industries is a technology company dedicated to developing advanced solutions for defense and critical industries. The company specializes in detection and radar services, leveraging its innovative Coherent Distributed Networks (CDN) to improve sensing, detection, and communication capabilities across multiple platforms. By focusing on the needs of defense clients, Chaos Industries enhances product development and ensures the delivery of high-quality services tailored to the demands of the sector.

Metronome is a billing infrastructure company focused on supporting software companies in launching, iterating, and scaling their usage-based business models. The company offers metering and data mediation software that enhances billing capabilities, ensuring a robust data infrastructure and real-time architecture tailored for usage-based billing. Metronome emphasizes rapid deployment, flexibility, and user-friendliness, reducing the engineering demands typically associated with billing systems. This enables business and product teams to manage revenue and pricing effectively. Following initial platform integration, teams can quickly introduce new products and pricing options, streamline revenue workflows, and grant customers immediate access to their spending insights.

Abcuro, Inc. is a biotechnology company focused on developing immunotherapies for the treatment of autoimmunity and cancer. Established in 2015 and headquartered in Newton, Massachusetts, Abcuro specializes in creating therapeutic antibodies that target novel pathways in these diseases. The company employs advanced bioinformatics to analyze transcription data from human diseases, enabling them to identify new therapeutic targets within the immune system. By leveraging clinical insights and systematic target validation, Abcuro aims to develop immune-modulatory biotherapeutics that provide innovative treatment options for patients suffering from autoimmune disorders and cancer.

Sana Labs is a leader in applying artificial intelligence to enhance educational outcomes through personalized learning. The company collaborates with prominent organizations to develop its innovative learning platform, which leverages advanced machine learning techniques. This platform is designed to empower education companies and integrates seamlessly with various applications, allowing employees to access knowledge, communicate, and automate tasks effectively. By offering insights into team strengths, weaknesses, and progress, Sana enables institutions in sectors such as healthcare, finance, and pharmaceuticals to improve their workforce's performance and learning experiences. The interdisciplinary team at Sana comprises experts from diverse fields, contributing to its mission of transforming the future of education.

Pathos is a company that focuses on enhancing the drug discovery process through its AI-enabled platform. This self-learning technology leverages big data and artificial intelligence to streamline the identification and validation of drug targets, ultimately establishing their clinical efficacy. By facilitating the exploration of novel concepts, Pathos aims to support drug developers in advancing innovative therapies. The platform is designed to manage the entire end-to-end process of designing and developing new therapeutics, thereby significantly reducing the time required for medication development.

Second Front Systems, Inc. is a technology company focused on enhancing government access to innovative, commercially developed technologies for national security applications. Founded in 2014 and headquartered in Arlington, Virginia, the company specializes in software solutions that facilitate the identification, assessment, and deployment of venture capital-backed technologies. Its primary product, Atlas Fulcrum, is a platform designed to streamline the discovery and engagement process for government users seeking advanced commercial technologies. Additionally, Second Front offers program management and system integration services to ensure the effective delivery of these technologies to military personnel. The company also operates the High Technology Council, an enterprise consortium that brings together key stakeholders to promote the application of venture-backed innovations in government-funded national security missions. With additional offices in Washington, D.C., and San Francisco, Second Front is positioned to transform how government entities access and utilize cutting-edge technology.

MBX Biosciences, Inc. is a biotechnology company founded in 2018 and based in Carmel, Indiana. The company specializes in developing therapeutics for rare endocrine disorders, focusing on conditions that currently lack effective treatments. MBX Biosciences aims to discover, develop, and commercialize first-in-class therapies, particularly peptides designed to address endocrine genetic diseases that affect glandular hormone production and the body’s chemical messaging systems.

Zenas BioPharma is a clinical-stage biopharmaceutical company headquartered in Florida, USA, that specializes in developing immune-based therapies for patients. The company’s lead product candidate, obexelimab, is a bifunctional monoclonal antibody designed to target both CD19 and FcγRIIb, which are found in B cell lineages. This innovative approach aims to inhibit the activity of cells involved in various autoimmune diseases while preserving their presence, thus avoiding depletion. Through its focus on these advanced therapies, Zenas BioPharma seeks to address unmet medical needs in the treatment of autoimmune conditions.

Perplexity is an artificial intelligence-based search engine platform that combines large language models with traditional search engines. It leverages natural language processing and generative AI technologies to deliver conversational responses to user queries, aiming to enhance the search experience beyond standard results. The platform is designed to facilitate the development of safe and beneficial artificial general intelligence, offering an open-source environment accessible to the public. This allows clients to acquire skills and knowledge in software development, positioning Perplexity as a bridge between conventional search capabilities and advanced AI-driven assistance.

Inkitt GmbH is a Berlin-based company founded in 2013 that operates an online community for writers and readers. It provides a platform for authors to share, review, and promote their stories across various genres, including horror, fantasy, romance, sci-fi, and more. Inkitt utilizes a unique data-driven approach to publishing, leveraging crowd wisdom and an algorithm called ReadRank to identify potential bestsellers. The platform allows authors to post their works-in-progress and receive feedback from readers, who can access these manuscripts for free for a limited time. Inkitt also encompasses interconnected applications, including Galatea, which sells optimized stories chapter by chapter, and GalateaTV, which adapts successful e-books into short-form television series. This ecosystem aims to create engaging storytelling experiences across multiple media, with a focus on hyper-personalization through AI to tailor content to individual preferences.

Pair Eyewear, Inc. is a New York-based company that specializes in customizable eyeglasses for children. Founded in 2017 by Nathan Kondamuri and Sophia Edelstein, the company offers a unique approach to eyewear by providing base frames and interchangeable top frames that allow kids to express their personal style and interests. By combining functionality with creativity, Pair Eyewear transforms glasses from mere medical devices into a fun and engaging accessory for children. The company's direct-to-consumer model leverages an e-commerce platform, making the purchasing process convenient for parents while enhancing the overall experience for young wearers. Pair Eyewear is committed to offering quality, affordable glasses that are both stylish and practical, featuring hand-polished frames and shatterproof polycarbonate lenses.

Pulumi Corporation is a Seattle-based cloud engineering company that specializes in an infrastructure-as-code platform for developing cloud software. Founded in 2017, Pulumi provides an open-source software development kit (SDK) that enables developers and DevOps teams to create, deploy, and manage cloud applications and infrastructure using familiar programming languages. The platform supports various cloud environments, including public, private, and hybrid clouds, facilitating the delivery of modern applications through a collaborative approach. Pulumi's tools and frameworks cater to a wide range of use cases, from serverless functions to containerized applications, allowing enterprises to effectively manage their cloud services and streamline their cloud engineering processes.

SpyGlass Pharma specializes in developing innovative treatments for chronic ophthalmic diseases through advanced technology. The company creates ophthalmic devices and a drug delivery platform aimed at enhancing vision and eye care for patients. Its products address unmet needs in areas such as cataracts, lens replacement, and surgical procedures. The drug delivery platform is designed to be implanted alongside intraocular lenses during standard cataract surgeries, allowing for the provision of multi-year therapy to treat chronic eye conditions. This approach not only facilitates effective treatment but also aims to make quality eye care more accessible and affordable for patients.

Instabase, Inc. is a technology company based in San Francisco, California, founded in 2015. It specializes in developing a platform that automates document processing workflows and analyzes unstructured data. The platform integrates various capabilities, including optical character recognition, data classification and extraction, and natural language processing, allowing organizations across sectors such as insurance, finance, and healthcare to streamline operations and improve decision-making. Additionally, Instabase provides a developer kit that enables the creation of customized business applications, helping institutions embed artificial intelligence into their systems and processes. Through its innovative solutions, Instabase aims to address significant business challenges and facilitate transformational outcomes for its clients.

Strive Health, LLC is a company focused on providing comprehensive solutions for chronic kidney disease. Founded in 2018 and based in Denver, Colorado, Strive Health operates dialysis centers and employs advanced predictive analytics to enhance patient care. The company offers a high-touch, technology-enabled clinical model that supports patients throughout their healthcare journey, from primary care engagement to dialysis treatment. By utilizing comparative and predictive data, Strive Health aims to identify at-risk patients and transform the management of kidney disease, promoting earlier intervention and increasing the adoption of home dialysis. This innovative approach not only improves patient outcomes but also seeks to reduce inpatient utilization, ultimately enhancing the overall experience for individuals dealing with chronic kidney conditions.

Mojo Vision Inc. is a technology company based in Saratoga, California, founded in 2015. The company specializes in the development of augmented reality solutions, focusing on high-performance micro-LED display technology. Mojo Vision has created the world's smallest and densest dynamic display for smart contact lenses, which are designed to provide users with timely information seamlessly and hands-free, without the distractions associated with traditional mobile devices. The company is also engaged in a joint development agreement with Menicon Co., Ltd. to explore smart contact lens products, further enhancing its innovative offerings. By combining advanced display and semiconductor expertise with proprietary quantum-dot technology, Mojo Vision aims to revolutionize the display industry, addressing diverse applications across consumer, enterprise, and government sectors.

Outrider, Inc. is a software company specializing in the automation of logistics hubs through the use of electric, self-driving trucks. Founded in 2017 and based in Golden, Colorado, the company provides a software-as-a-service solution tailored for customer-owned fully and semi-autonomous freight and transportation fleets. Outrider's innovative system comprises web-based management software, autonomous driving controls for electric yard trucks, and essential site infrastructure. The autonomous vehicles are equipped with advanced sensor technology, including radar, lidar, and cameras, enabling them to automate various yard operations such as the movement of trailers, engaging and unhooking trailers, and monitoring trailer locations. The company's focus is on enhancing safety and efficiency for large enterprises by replacing hazardous and repetitive manual tasks with automated processes, thereby driving the adoption of sustainable freight transportation.

Escient Pharmaceuticals, Inc. is a biotechnology company based in San Diego, California, specializing in the development and manufacture of G protein-coupled receptor (GPCR)-targeted drugs aimed at treating neuro-immuno-inflammatory and autoreactive diseases. Founded in 2017, Escient focuses on harnessing the therapeutic potential of specific orphan GPCRs, particularly the Mas-Related G-Protein Receptors (Mrgprs). The company aims to provide innovative therapies for a variety of conditions, including mast cell-mediated disorders and cholestatic pruritus, thereby expanding treatment options for healthcare providers facing these complex diseases.

Inversago Pharma Inc. is a preclinical-stage biotechnology company based in Montreal, Canada, specializing in the development of peripherally-restricted CB1 receptor inverse agonists aimed at treating various metabolic and fibrotic disorders. Founded in 2015, the company focuses on creating innovative therapies for conditions such as Prader-Willi syndrome, diabetes, and complications related to obesity. Its pipeline includes treatments for diabetic kidney disease, non-alcoholic steatohepatitis, and progressive fibrosis, including interstitial lung disease. Inversago Pharma aims to improve patient outcomes by offering new therapeutic options that target the underlying mechanisms of these diseases.

Evident is a leader in business credentialing, providing a comprehensive platform that connects insurers, enterprises, and businesses worldwide. With a presence in over one hundred countries, the company specializes in identity and credential verification, enabling its clients to ensure compliance with specific requirements. Utilizing advanced artificial intelligence, Evident’s platform combines thorough credentialing processes with efficient business outcomes. The technology allows for the identification and management of risks across multiple domains, offering data-driven insights and a flexible framework tailored to individual client needs. Thus, Evident empowers its clients to proactively manage third-party risk while streamlining the verification process.

Moximed, Inc. is a medical technology company based in Hayward, California, that focuses on developing innovative treatments for patients with knee osteoarthritis. The company offers the Atlas System, an implantable joint unloader designed to alleviate pain associated with medial compartment knee osteoarthritis, allowing patients to maintain high levels of activity. Additionally, Moximed has developed the MISHA Knee System, which provides an outpatient treatment option for individuals who have not responded to conventional therapies and are not suitable candidates for knee replacement surgery. By minimizing joint pain and providing dynamic load reduction, Moximed's implants aim to improve the standard of care and enhance the quality of life for patients, potentially delaying or avoiding the need for more invasive surgical interventions. Moximed has been operational since its incorporation in 2006, serving patients and medical professionals globally.

Super is a social commerce platform that enables leaders to become self-made entrepreneurs and builds logistics networks. The company features Superagen, an agent-led commerce group buying that enables community leaders to become retailers within their communities.

Genies, Inc. is a company specializing in avatar technology, enabling users to create personalized digital avatars for social media and messaging applications. By offering tools for designing avatars, avatar wearable fashion, and interactive experiences, Genies allows individuals to express their thoughts and feelings in a unique digital format. The company has gained significant traction among cultural influencers and has partnered with major music labels, serving as the official avatar provider for their artists. Genies has also launched consumer offerings, including an AR Developer Kit that facilitates the creation of interoperable avatar experiences in augmented reality. Their initial product, Silver Studio, allows users to design and trade digital fashion items. Founded in 2011 and headquartered in Venice, California, Genies has successfully raised substantial investment, positioning itself as a leader in the avatar space and driving engagement for brands through the sale of exclusive digital goods.

Built Robotics Inc. is a technology company focused on automating the construction industry through the development of AI guidance systems that transform heavy equipment into autonomous robots. Founded in 2016 and headquartered in San Francisco, California, the company integrates various sensors, including GPS, cameras, and Lidar, with advanced software to enable earthmoving equipment to operate autonomously. Built Robotics aims to address the workforce gap in the construction sector, particularly in the $300 billion solar industry, by automating repetitive tasks and facilitating the construction of critical infrastructure such as wind farms, oil and gas pipelines, and new housing developments.

Timescale, Inc., established in 2011 and headquartered in New York with offices in Stockholm and Los Angeles, specializes in data analysis platforms designed for scale, ease of use, and complex queries. Its flagship product, TimescaleDB, is an open-source time-series database that supports full SQL, optimized for advanced analytics and production use cases. Timescale serves software developers and businesses worldwide, enabling them to build and analyze time-series and machine data applications.

Beyond Identity, Inc. is a New York-based company that specializes in cloud-native passwordless identity management solutions. Founded in 2019, it aims to enhance digital security by replacing traditional passwords with secure, X.509-based certificates. This innovative approach creates a robust Chain of Trust, incorporating user and device identity along with a real-time assessment of device security for adaptive authentication and authorization. Beyond Identity's platform facilitates frictionless login experiences through biometric authentication and seamless integration with Single Sign-On (SSO) systems, catering to employees, contractors, and customers alike. By eliminating the use of passwords, the company helps organizations mitigate risks associated with credential-stuffing attacks and streamline their authentication processes, ultimately enabling greater business agility and cost efficiency.

FTX is a cryptocurrency exchange company that specializes in developing a professional trading platform, supporting features such as quarterly and perpetual futures, leveraged tokens, and OTC trading. It aims to cater to both professional trading firms and first-time users, offering an intuitive and robust trading environment. FTX was incubated by Alameda Research, ensuring it had industry order books from its inception. Additionally, FTX Ventures, its investment arm, provides equity and/or token investments to blockchain companies at various stages, supporting founders and maintaining their decision-making flexibility.

Virtru is a data security company based in Washington, D.C., founded in 2012. It specializes in providing organizations with a comprehensive platform that balances data protection with user convenience. Virtru's offerings include the Trusted Data Format (TDF), an open industry standard for persistent data protection, which enables organizations to secure sensitive information throughout its entire lifecycle—from creation to sharing. With over 20,000 clients across various industries, Virtru ensures compliance with regulations such as HIPAA, FERPA, and ITAR, allowing businesses to maintain control over their data regardless of its location. The company's technologies are designed to empower organizations to leverage their data securely while adhering to privacy standards.

InCarey is a Shanghai-based company founded in 2011 that specializes in developing a comprehensive medical service platform focused on the management of chronic and vertical diseases. The platform integrates medical, pharmaceutical, and insurance resources to provide a one-stop solution for patients requiring long-term care and support. InCarey's cloud-based online platform facilitates professional disease management services, allowing for direct interaction between doctors and patients. Additionally, it includes an e-commerce component that enables users to conveniently access medications for various chronic conditions. The company is dedicated to enhancing the patient experience through innovative payment services and a holistic approach to chronic disease management.

Forethought, established in 2017 and based in Palo Alto, specializes in developing AI models for question-answering and information retrieval. Its flagship product, Agatha Answers, is a smart agent that integrates into customer support teams' workflows, providing real-time assistance, automating repetitive tasks, and offering predictive insights to enhance efficiency and productivity.

Anyscale, Inc. is a technology company that focuses on simplifying distributed AI development through its innovative programming platforms and tools. Founded in 2019 by the creators of Ray, Anyscale has developed the Ray framework, which is an open-source project that allows software developers and machine learning engineers to effortlessly scale their applications from a personal laptop to cloud environments. The company's solutions enable developers of varying skill levels to manage the complete AI lifecycle on a unified computing substrate, facilitating the rapid development and deployment of AI products. Based in Berkeley, California, Anyscale aims to accelerate the productionization of AI applications, making it easier and more cost-effective for organizations to bring AI solutions to market.

Block Renovation is a home renovation platform that aims to simplify the complex process of planning, designing, and executing home improvements. Founded by Koda Wang and Luke Sherwin, the company integrates architect-grade design, construction labor, and materials into a cohesive experience. By bringing design, sourcing, and project management under one roof, Block Renovation provides homeowners with clarity regarding outcomes, quality, pricing, and timelines. This streamlined approach not only enhances the renovation experience for homeowners but also offers contractors a more efficient way to operate. Ultimately, Block Renovation seeks to improve living spaces while elevating the standards of the renovation industry.

Stride Health, Inc. is a health benefits platform that specializes in providing affordable health coverage options for independent workers and part-time employees in the United States. The company offers a range of services, including dental plans, doctor and prescription insurance plans, and various health coverage options tailored to meet the needs of its customers. Stride Health simplifies the enrollment process by guiding users through selecting the most cost-effective health plans, aiming to optimize their tax benefits and enhance their take-home pay. Founded in 2013 and based in San Francisco, California, the company was previously known as Covered, Inc. and rebranded to Stride Health, Inc. in March 2013. Stride Health also provides personal advisory services to assist clients in navigating the complexities of their health insurance options.

Clarifai, Inc. is a prominent provider of advanced artificial intelligence solutions specializing in image recognition, natural language processing, and audio recognition. Established in 2013 and headquartered in New York, the company has developed a comprehensive platform that allows organizations to transform unstructured data—such as images, videos, and text—into structured formats with greater speed and accuracy than human capabilities. Clarifai's technology includes sophisticated systems for detecting near-duplicates and enabling visual searches, as well as a labeling tool that assists users in managing and training AI models. The company has gained recognition for its innovation in the field, notably securing top positions in the 2013 ImageNet Challenge. With a workforce spread across various countries, including the United States, Canada, Estonia, Argentina, and India, Clarifai continues to lead in the AI landscape by enhancing the way organizations utilize visual data.

Sisu is a decision intelligence engine that allows users to efficiently and comprehensively utilize their cloud data. Companies such as Mastercard, Autodesk, Samsung, Upwork, Wayfair, Equinox, Udacity, and Gusto leverage Sisu to enhance their customer experiences, increase revenue growth, and reduce incident rates.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

Allay Therapeutics is focused on developing innovative solutions for post-surgical pain management, aiming to enhance patient recovery experiences. The company utilizes a proprietary technology platform that integrates validated non-opioid analgesics with biopolymers to create dissolvable therapeutics. These products are designed to deliver targeted pain relief over extended periods, significantly surpassing the duration of existing pain treatments. Allay's lead investigational product, ATX101, is currently undergoing evaluation in a Phase 2 clinical study for total knee arthroplasty surgeries. With a diverse team of entrepreneurs, scientists, and clinicians based in the San Francisco Bay Area and Singapore, Allay Therapeutics seeks to address the limitations of conventional pain management approaches, particularly the challenges associated with opioid use.

Tulip Interfaces, Inc. is a technology company specializing in the development of shop floor applications for the manufacturing industry. Founded in 2012 and based in Somerville, Massachusetts, Tulip provides a no-code platform that enables companies to enhance productivity, quality, and operational efficiency. Its applications integrate data from sensors and connect existing shop floor equipment, allowing for real-time visualization of relevant information. Tulip's platform is designed for various industries, including consumer electronics, pharmaceuticals, apparel, aerospace, automotive, and medical devices. By empowering frontline workers with intuitive software and hardware tools, Tulip facilitates digital transformation in manufacturing, helping organizations address critical challenges and improve their operations through enhanced visibility and traceability.

ARRIS specializes in advanced manufacturing technologies, particularly in the development of performance composites for various mass-market applications, including aerospace, automotive, and consumer products. The company's innovative additive molding technology enables the production of 3D-aligned continuous fiber thermoplastic composite parts at scale. This proprietary process allows for the precise alignment of continuous carbon fibers and the integration of electronic components and multifunctional materials into a single, topology-optimized structure. By combining these elements, ARRIS provides clients with access to advanced composite solutions that enhance product performance and efficiency.

Aetion, Inc. is a healthcare analytics company that specializes in real-world evidence (RWE) and outcomes-based analytics solutions. Founded in 2012 and based in New York City, Aetion develops the Aetion Evidence Platform, which leverages everyday clinical and financial interactions within the healthcare system to generate critical insights about the effectiveness and value of medical treatments. This platform serves a diverse clientele, including life sciences companies, payers, providers, medical device manufacturers, and academic institutions, allowing them to analyze data from various sources such as claims, electronic health records, registries, and clinical trials. Aetion’s patented rapid-cycle analytics technology facilitates real-time collaboration among stakeholders, enabling them to make informed decisions and optimize patient care. The company has formed strategic partnerships with leading organizations, including McKesson, to enhance its offerings and expand its reach in the healthcare sector.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Arcellx is a clinical-stage biotechnology company focused on developing innovative immunotherapies, particularly in the realm of cell therapy, for patients with cancer and other serious diseases. The company aims to enhance the safety, effectiveness, and accessibility of these therapies. Arcellx's lead product candidate, CART-ddBCMA, is currently being investigated in a Phase 1 clinical trial for the treatment of relapsed or refractory multiple myeloma. This therapy has received several designations from the U.S. Food and Drug Administration, including Fast Track and Orphan Drug status. Additionally, Arcellx is progressing its dosable and controllable CAR-T therapy, known as ARC-SparX, through two clinical programs targeting relapsed or refractory multiple myeloma and acute myeloid leukemia. Through these efforts, Arcellx seeks to contribute significantly to the advancement of cell therapy in modern medicine.

Cleo Labs, Inc. is a family support platform that offers pregnancy consultancy and parenthood guidance services to working parents. The company provides a range of consultation services, including lactation support, birth preparation, child wellness, and sleep consulting, as well as career coaching and immediate post-birth assistance. Cleo's mobile application connects families with certified care practitioners, facilitating their journey from fertility through parenting children up to age five. By partnering with employers, Cleo aims to enhance workplace culture, improve employee retention, and foster diverse and inclusive environments. The company operates globally, serving clients in over 50 countries and has collaborated with notable organizations such as eBay and LinkedIn. Founded in 2016 and headquartered in San Francisco, Cleo was previously known as Instacare Group, Inc. before rebranding in 2018.

Monte Rosa Therapeutics is a biotechnology company dedicated to developing innovative cancer therapeutics through the modulation of protein degradation pathways. Specializing in molecular glue degraders (MGDs), the company utilizes the body's natural mechanisms for protein destruction to selectively degrade proteins that are relevant to therapeutic outcomes. Employing its QuEEN platform, which integrates artificial intelligence and proprietary experimental tools, Monte Rosa identifies target proteins for degradation by MGDs from its extensive library of over 50,000 molecules. The company's most advanced product candidate, MRT-2359, specifically targets the translation termination factor protein GSPT1, showing promise for the treatment of MYC-driven tumors. Monte Rosa Therapeutics aims to deliver pioneering therapies for cancer and potentially other diseases through its innovative approaches.

Nuvolo Technologies Corporation offers a cloud-based enterprise asset management platform designed to support the lifecycle management of assets in various sectors, including healthcare, manufacturing, and facilities management. Founded in 2013 and headquartered in Paramus, New Jersey, Nuvolo innovates on the ServiceNow platform to provide a user-friendly experience for mobile and online users. The company’s solutions encompass implementation, support, tracking, reporting, and analytics, aimed at optimizing operational efficiency and improving asset management. Nuvolo also emphasizes security, workflow automation, and accurate inventory data, making it a comprehensive choice for businesses looking to enhance their asset management capabilities. With additional offices in London, Sofia, and Pune, Nuvolo maintains a global presence through strategic partnerships with firms such as KPMG and Unisys.

Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.

Personal Genome Diagnostics, Inc. is a biotechnology company focused on patient-specific analyses of cancer genomes. Established in 2010 and headquartered in Baltimore, Maryland, the company has pioneered technologies for non-invasive "liquid biopsy" approaches, allowing for the detection of tumor-specific alterations in circulating cell-free DNA. Its offerings include the METDetect Assay for identifying MET gene amplifications, LungSelect for detecting actionable genetic alterations in non-small cell lung cancer patients, and PGDx elio plasma resolve, which analyzes various genetic mutations from plasma samples. Additionally, Personal Genome Diagnostics provides RNAcomplete, enabling researchers to extract both RNA and genomic DNA from a single tissue sample, and CancerXOME, which captures and analyzes coding regions of genes. The company collaborates with institutions like Mayo Clinic and partners with KingMed Diagnostics to enhance its research and diagnostic capabilities, thereby empowering oncologists and researchers with crucial genomic insights to combat cancer.

Sitetracker is a software-as-a-service (SaaS) platform that specializes in the deployment, operation, and servicing of critical infrastructure and technology. It provides a comprehensive project management solution tailored for high-volume, repeatable, and distributed projects across industries such as telecommunications, alternative energy, and utilities. The Sitetracker platform utilizes features like artificial intelligence, automation, and actionable analytics to optimize the entire asset lifecycle. By conducting capacity planning and leveraging vendor analytics, it helps organizations identify staffing needs and resource bottlenecks, enabling stakeholders to effectively plan, deploy, maintain, and grow their capital asset portfolios. Industry leaders, including major companies in telecommunications and utilities, depend on Sitetracker to manage millions of sites and projects, collectively representing significant portfolio holdings worldwide.

KONUX GmbH is a German company based in Munich, founded in 2014, that specializes in developing Industrial Internet of Things (IIoT) solutions for railway and industrial applications. The company integrates smart sensor systems with artificial intelligence-driven analytics to provide real-time monitoring of asset and infrastructure conditions, enabling predictive maintenance and enhancing operational efficiency. KONUX's offerings include switch monitoring, asset monitoring, rolling stock monitoring, anomaly detection, and customized hardware solutions. By leveraging machine learning and IoT technologies, KONUX aims to transform railway operations, making them more sustainable, reliable, and cost-effective. The company has expanded its footprint across Europe and Asia and has gained recognition as one of the most innovative startups globally, underscoring its commitment to modernizing transportation systems.

Bestow Inc., established in 2016 and based in Dallas, Texas, operates as a digital life insurance company. It provides life insurance services to individuals, leveraging data-driven technology applications and algorithmic underwriting to assess risks efficiently. The company partners with top carriers to enhance processes from origination to administration, aiming to increase financial stability for all.

Alfred Club, Inc. is a technology-driven company that provides a resident experience and building management platform designed for apartment buildings. Founded in 2013 and based in New York, Alfred offers the Hello Alfred program, which allows residents to outsource everyday tasks such as package receiving and dog walking to dedicated home managers. These home managers are W-2 employees, ensuring they receive benefits and training, which enhances service quality and fosters local community support. The platform integrates various services, enabling residents to request assistance with grocery delivery, home cleaning, and access to exclusive events and virtual classes, all through a single, intuitive interface. Alfred has been recognized as a leader in transforming the real estate industry and has gained media attention for its innovative approach to enhancing the residential living experience.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Everactive, Inc., based in Santa Clara, California, specializes in developing wireless sensing devices and technologies for Industrial IoT analytics. Founded in 2012 and formerly known as PsiKick, the company offers custom ultra-low-power chips that enable battery-less wireless sensors, forming the backbone of its end-to-end IoT data services. Everactive's innovative circuit design and wireless communication capabilities allow for intelligent instrumentation of industrial operations, providing solutions such as steam trap monitoring, flare system monitoring, and machine health monitoring. The company's technology focuses on enabling low-cost, long-lived devices powered exclusively by harvested energy, allowing for continuous data analysis across a wide range of applications. In addition to its headquarters, Everactive has locations in Charlottesville, Virginia, and Ann Arbor, Michigan.

Amplyx Pharmaceuticals, Inc. is a small molecule drug development company focused on creating innovative therapies for debilitating and life-threatening diseases, particularly those affecting individuals with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in the development of oral and injectable anti-infective drugs, including antifungal agents designed to treat invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by incorporating a second small molecule. This strategy aims to provide effective treatment options for patients undergoing chemotherapy and other immunosuppressive therapies, ensuring they receive appropriate care both during hospitalization and after discharge.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

ChromaCode Inc., established in 2012 and based in Carlsbad, California, specializes in molecular diagnostics. The company develops innovative testing solutions for infectious diseases, cancer, and non-invasive prenatal testing (NIPT) using technology licensed from Caltech. ChromaCode's core products are software, reagents, and assays that enhance the multiplexing capabilities of quantitative PCR (qPCR) instruments by fivefold. Additionally, they offer molecular assays and software for various applications such as personalized medicine and pharmaceutical research. One of their notable products is the HDPCR Tick-Borne Pathogen Panel, a multiplex PCR test detecting common tick-borne pathogens in a single assay. ChromaCode's technology focuses on improving signal processing from life science instrumentation, enabling cost-effective testing of multiple targets simultaneously while integrating into existing laboratory workflows.

Black Diamond Therapeutics, Inc., established in 2014 and headquartered in Cambridge, Massachusetts, specializes in precision oncology medicine. The company discovers and develops small molecule therapies that are tumor-agnostic, meaning they target specific genetic mutations across various cancer types rather than being limited to a single cancer indication. Its lead product candidate, BDTX-189, inhibits non-canonical and oncogenic mutations of ErbB kinases epidermal growth factor receptor (EGFR). The company's Mutation-Allostery-Pharmacology platform enables it to target undrugged mutations in patients with genetically defined cancers, offering new treatment options where few exist. Black Diamond Therapeutics is also advancing early-stage pipeline programs targeting allosteric mutations in other cancer-related kinases.

Sentry is an open-source platform focused on improving workflow productivity by monitoring application performance and error reporting. The company provides a tool that captures real-time data on errors and crashes within software applications, allowing users to prioritize and identify issues as they occur. This tool offers detailed insights into deployments and assists in reproducing and fixing crashes, enabling organizations to understand which errors are most detrimental to their operations. By highlighting the impact of these issues on business performance, Sentry helps its clients enhance their software reliability and ultimately improve their bottom line.

PlayVS is an operator of an eSports platform designed to facilitate organized competitions for high schools. The company provides a platform that enables the organization of online tournaments, allowing students to compete against one another for cash prizes and titles. By fostering eSports programs in high schools, PlayVS helps teen gamers form teams and engage in competitive play, connecting them with players from other schools and creating opportunities to participate in state championships. This initiative aims to enhance the overall experience of high school eSports, ensuring that both players and schools can stay informed and involved in the rapidly evolving world of competitive gaming.

Echodyne, established in 2014 and based in Kirkland, Washington, specializes in developing and marketing metamaterials-based radar systems. The company offers a range of radar solutions, including 3D Security radar for all-weather, compact, and solid-state sensor performance; Metamaterial Electronically Scanning Array (MESA) technology for high-performance phased-array radar at breakthrough cost levels; and Echoguard for ground-based airspace management. Additionally, Echodyne provides Acuity Software for customization and data processing, along with various deployment kits and accessories. Their products cater to commercial markets, government, defense, and industry, enabling autonomous applications in drones, vehicles, and heavy machinery, even in complex and challenging environments.

Heap Inc. is a company that develops an analytics infrastructure designed for online businesses, enabling them to capture and analyze customer interactions across web, mobile, and cloud platforms. Founded in 2012 and headquartered in San Francisco, California, Heap's solution automates the collection and organization of customer behavioral data, such as clicks, transactions, and form submissions, without requiring additional coding. This streamlined approach allows businesses to gain a comprehensive understanding of their users, facilitating informed decision-making and enhancing product development. Heap serves a diverse range of industries, including e-commerce, financial services, and SaaS, with over 6,000 clients that include notable companies across various sectors. The company is committed to empowering organizations to focus on insights and actions that drive business success.

Expel, Inc. is a cybersecurity company that specializes in managed security software and services. Founded in 2016 and based in Herndon, Virginia, Expel offers a comprehensive security operations center (SOC)-as-a-service, which includes managed detection and response (MDR), threat hunting, remediation, and phishing support. The company’s platform, known as the Expel Workbench™, facilitates a collaborative experience, allowing customers to engage actively in their security operations. Users can monitor live investigations or receive detailed alerts throughout the investigative process. Expel’s approach emphasizes transparency and efficiency, enabling security teams to focus on strategic priorities while swiftly addressing threats such as ransomware, phishing, and supply chain attacks. With dedicated analysts available around the clock, Expel aims to enhance organizations' security posture by swiftly identifying and mitigating risks while reducing the noise of false positives.

Tamara Mellon, LLC is a fashion company that specializes in women's apparel and accessories, primarily focusing on footwear. Founded in 2011 by Tamara Mellon and Jill Layfield, the company is headquartered in New York City. Tamara Mellon offers a diverse range of products, including sandals, boots, pumps, flats, and legging boots, as well as handbags and ready-to-wear items such as dresses, jumpsuits, tops, pants, and outerwear. It operates both retail and online stores, serving customers in the United States and internationally. The brand is noted for its commitment to quality and accessibility, boasting a unique platform that includes a complimentary cobbler service for two years post-purchase, ensuring that customers can maintain their designer footwear.

Expanse, Inc. is an enterprise software company based in San Francisco, California, specializing in data marshalling services to enhance the security and management of global internet assets. Founded in 2012 and formerly known as Qadium, Inc., the company provides an innovative platform that offers organizations an updated view of their internet-connected assets. This platform enables IT and security teams to gain visibility into their global internet attack surface, identifying unknown assets and managing exposure to online threats. Expanse's technology indexes global IP addresses, DNS protocol information, and registration records, allowing organizations to improve governance and IT operations while minimizing risks associated with their internet presence. Trusted by major enterprises and government agencies, Expanse monitors and tracks over 400 million internet- and cloud-connected assets, representing more than 10% of the global Internet, to enhance awareness and prevent successful cyberattacks.

Igneous Systems, Inc., founded in October 2013 and headquartered in Seattle, Washington, specializes in enterprise data center infrastructure and unstructured data management. The company offers a comprehensive as-a-Service solution that provides businesses with visibility, protection, and mobility for their unstructured data on a large scale. Igneous’s cloud-native, API-enabled platform integrates various unstructured data management functions, allowing organizations to maximize the value of their data while minimizing risks and optimizing IT resource utilization. Its services include consolidated backup, file system archiving, and efficient management of unstructured data, all aimed at enhancing workflow productivity for data-centric enterprises.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, established in 2011. The company specializes in the development and commercialization of Haduvio, an oral extended-release formulation of nalbuphine. Haduvio is currently undergoing a Phase IIb/III clinical trial, known as the PRISM trial, aimed at treating chronic pruritus associated with prurigo nodularis. Additionally, Trevi is exploring the use of nalbuphine ER for other serious neurologically mediated conditions, including chronic cough in patients with idiopathic pulmonary fibrosis and levodopa-induced dyskinesia in individuals with Parkinson’s disease. The treatment targets conditions that share a common pathophysiology mediated through opioid receptors in the central and peripheral nervous systems.

The Wing is a network of work and community spaces designed specifically for women, with locations in New York, California, and Washington, D.C. The organization aims to foster the professional, civic, social, and economic advancement of women by providing a supportive environment. Its facilities include open-plan workspaces, meeting rooms, phone booths, and an extensive library curated for women. The Wing creates a community of professional women, facilitating connections and support among female founders, thereby inspiring and empowering them to grow their businesses and achieve their goals.

Annexon Biosciences is a clinical-stage biopharmaceutical company focused on developing novel therapies for patients with classical complement-mediated disorders affecting the body, brain, and eye. The company's pipeline is built on a platform technology that targets well-researched autoimmune and neurodegenerative disease processes triggered by the aberrant activation of C1q, the initiating molecule of the classical complement pathway. Annexon's lead product candidate, ANX005, is a full-length monoclonal antibody designed for intravenous administration to treat autoimmune and neurodegenerative disorders. Another key candidate, ANX007, is a monoclonal antibody Fab formulated for intravitreal administration to address neurodegenerative ophthalmic disorders. The company employs a biomarker-driven development strategy to ensure that its product candidates effectively engage the target at therapeutic doses within the intended patient tissue, while also exploring additional orphan and large market indications.

Plaid Inc. is a technology company that facilitates the connection between consumers' bank accounts and applications, aiming to democratize financial services through advanced technological solutions. Founded in 2012 and headquartered in San Francisco, it provides a comprehensive suite of APIs that enable developers to create financial products connecting users with traditional financial institutions. Plaid's offerings include tools for accessing transaction history and balance data, authenticating bank accounts for payments, verifying identities, and confirming real-time account balances and income. These products support various applications in personal finances, consumer payments, lending, banking, and business finance. With a focus on enhancing both consumer experiences and developer capabilities, Plaid serves a diverse range of clients, including Fortune 50 companies, positioning itself as a vital infrastructure provider in the digital financial landscape.

NeueHealth Inc is a healthcare company dedicated to providing high-quality, coordinated care to all health consumers, particularly those in aging and underserved populations. The company focuses on making healthcare accessible and affordable through strategic partnerships with providers and payors, aligning their interests to enhance the overall healthcare experience. By leveraging technology and data analytics, NeueHealth offers a suite of services that empower independent providers and medical groups to succeed in performance-based arrangements. This approach not only optimizes clinical outcomes but also aims to drive down costs and reduce systemic waste, ultimately delivering a more personalized and efficient healthcare experience for its members across various insurance markets, including the ACA Marketplace, Medicare, and Medicaid.

Infoworks.io, Inc. is an enterprise software company that specializes in automated data management solutions for organizations seeking to optimize their cloud data operations. Founded in 2014 and headquartered in Palo Alto, California, with an additional office in Bengaluru, India, Infoworks offers its flagship product, DataFoundry, which facilitates the discovery, loading, organization, and management of data on Hadoop. The platform supports data operations and orchestration, enabling organizations to streamline workflows from data ingestion to analytics in various environments, including cloud, multi-cloud, and hybrid settings. Infoworks' solutions encompass data ingestion, synchronization, preparation, cube generation, and workflow management, significantly accelerating cloud migration processes and modernizing data operations while reducing costs. By enhancing agility and scalability, Infoworks empowers enterprises to leverage their data for advanced analytics, artificial intelligence, and machine learning applications more efficiently.

HEAVY.AI is a developer of a big data analytics and visualization platform that enables businesses and government entities to uncover valuable opportunities and risks within extensive location and time-based data. By leveraging the capabilities of modern GPU and CPU hardware, HEAVY.AI's platform provides a structured query language-compliant database and an advanced visual analytics engine. This technology allows users to effectively analyze and visualize multi-billion record datasets through a web-based interface. The company's solutions are utilized across various sectors, including government, telecommunications, energy, utilities, and higher education, facilitating high-impact decision-making and enhancing the ability to derive insights from complex data.

Galera Therapeutics, Inc. is a clinical-stage biopharmaceutical company headquartered in Malvern, Pennsylvania, dedicated to developing innovative therapeutics aimed at enhancing the effectiveness of radiotherapy for cancer patients. The company's lead product candidate, avasopasem manganese (GC4419), is a small molecule dismutase mimetic currently undergoing Phase III clinical trials for the treatment of radiation-induced severe oral mucositis in patients with head and neck cancer. Additionally, GC4419 is being evaluated in Phase IIa trials for the treatment of radiotherapy-induced esophagitis in lung cancer patients. Galera is also advancing another candidate, GC4711, which is in Phase I/II trials for pancreatic and lung cancers. The company's research is focused on targeting oxygen metabolic pathways to improve patient outcomes in radiation therapy, and GC4419 has received Fast Track and Breakthrough Therapy designations from the U.S. Food and Drug Administration.

Enigma Technologies, Inc. is an operational data management and intelligence company based in New York. It specializes in providing a searchable database of public records, information, and documents, facilitating streamlined operations and informed decision-making for its users. The company offers a suite of products, including Enigma Data Infrastructure, which features tools for data operations and metadata enhancement, and Enigma Solutions, tailored for specific industries such as financial services, pharmacovigilance, and insurance. Enigma also provides analysis-ready public data relevant to sectors like oil and gas, healthcare, and company reference data. Additionally, Enigma operates Enigma Labs, which focuses on developing open data tools for public use, and offers an API to support developers in creating data-rich applications. The company is recognized for its contributions to small business intelligence, delivering timely and accurate insights on the identity and risk profile of small businesses, thus aiding firms in areas such as insurance risk assessment and fraud prevention. Enigma Technologies was incorporated in 2011.

StreamSets, Inc. is a developer of a cloud-based DataOps platform that facilitates modern data integration for enterprises, enabling the continuous flow of big, streaming, and traditional data into data science and analytics applications. Founded in 2014 and headquartered in San Francisco, California, the company offers solutions such as StreamSets Control Hub for designing and monitoring data pipelines, StreamSets Data Collector as an open-source execution engine for managing both streaming and batch data, and StreamSets Transformer for building data transformations across various sources. The platform supports diverse use cases, including integration for data lakes and warehouses, cloud data storage adoption, and the powering of real-time applications. StreamSets serves enterprise clients both in the United States and internationally, with additional offices in locations including Sunnyvale, Austin, London, Barcelona, Bengaluru, and Sydney.

MORE Health, Inc. is a healthcare technology company that has developed a cloud-based physician collaboration platform to facilitate joint diagnosis and treatment planning between attending doctors and specialists. Founded in 2013 and based in Foster City, California, the platform integrates a clinical database containing medical histories, hospital records, lab results, and medical images, along with secure communication tools for real-time discussions. MORE Health offers a variety of services, including a patient portal for personal health records, an Overseas Co-Diagnosis service for international patients, and a Secure Medical Record service for traveling employees. Initially launched as a concierge service for private clients, it now serves U.S. companies as a supplemental health benefit, providing employees access to top-tier medical expertise during serious health issues. With strategic alliances with prominent medical institutions, MORE Health aims to become a virtual global hospital for serious illnesses, ensuring patients receive the highest quality of diagnosis and treatment when needed.

Brandless, Inc. is an online consumer commerce platform based in San Francisco, California, that offers a diverse range of products across several categories. Founded in 2015, the company sells food items such as snacks, granola, and baby food, as well as home essentials including cleaning supplies, tableware, and office products. Additionally, Brandless provides beauty and personal care items, health and wellness products like vitamins and supplements, baby products, and pet supplies. The company aims to create a marketplace that empowers consumers to make healthier and more sustainable choices for themselves, their families, and the environment by prioritizing quality and collaboration.

Tuya is a global developer platform specializing in artificial intelligence and the Internet of Things (IoT). It connects consumers, manufacturers, OEMs, and retail chains, providing a comprehensive solution that includes hardware access, cloud services, and app development. This ecosystem enables businesses to enhance their consumer IoT smart devices and meet increasing consumer demands. As of late 2018, Tuya had served 93,000 customers and connected over 100 million smart products globally, with a product catalog exceeding 30,000 listings across nearly 200 countries. The company operates a distributed IoT cloud platform that processes nearly 50 billion device requests daily and facilitates over 20 million voice AI interactions each day, accumulating a data volume of 15 petabytes. Tuya's offerings include platform-as-a-service and software-as-a-service options, fostering a vibrant IoT ecosystem that encourages collaboration among brands, OEMs, partners, and end users.

Framebridge, Inc. specializes in providing custom framing solutions for art and photographs through an online platform. Founded in 2013 and headquartered in Washington, D.C., the company simplifies the traditionally cumbersome and costly custom framing process. Customers can select from a curated range of contemporary frame styles, upload their images directly on the website, or send physical items in prepaid packaging for framing. Framebridge's expert team handcrafts each frame to meet the specific requirements of the customer, ensuring high-quality results. The finished products are then shipped directly to consumers, typically within days and ready for display. The company's pricing is transparent and based on the size of the framed item, starting at $39 and inclusive of free shipping. Framebridge aims to make custom framing accessible and efficient, enhancing the overall customer experience.

Nginx, established in 2011, is a technology company that specializes in developing and maintaining the open-source web server NGINX. Its offerings include application delivery, load balancing, security, and API management solutions. Key products are NGINX Plus, a software load balancer and web server; NGINX Controller, for managing NGINX Plus; NGINX Unit, a dynamic application server; NGINX Web Application Firewall; and NGINX Amplify, a SaaS monitoring tool. Headquartered in San Francisco, with offices in Cork and Singapore, Nginx operates as a subsidiary of F5 Networks.

Metacrine, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, established in 2014. It specializes in the discovery and development of innovative therapies aimed at treating liver and gastrointestinal diseases. The company is advancing a pipeline of drug candidates, with a primary focus on the farnesoid X receptor (FXR), a key target in managing various liver and GI disorders. Its lead candidates, MET409 and MET642, are currently in clinical trials to evaluate their efficacy in treating non-alcoholic steatohepatitis. Additionally, Metacrine collaborates with Novo Nordisk A/S to explore further research opportunities related to fibroblast growth factor 1. The company is committed to developing best-in-class therapies to improve patient outcomes in these challenging medical areas.

XSKY Data Technology, based in Beijing, specializes in software-defined infrastructure products and services. It offers a range of storage solutions, including XCBS (cloud), XEBS (block), XEUS (unified), XEOS (object), and XEDP (unified data platform), catering to diverse sectors such as finance, telecom, energy, and government. XSKY is a significant contributor to the open-source Ceph storage system, ranking top 3 globally. It partners with leading tech companies like Intel and Samsung, providing scalable, cost-effective storage solutions tailored for enterprise needs.

Intact Vascular, Inc. is a medical device company based in Wayne, Pennsylvania, specializing in the development of minimally invasive products for peripheral vascular procedures. Founded in 2011, the company is known for its Tack Endovascular System, which aims to enhance the results of peripheral balloon angioplasty in treating peripheral arterial disease (PAD) and critical limb ischemia (CLI). Intact Vascular focuses on creating safe and effective solutions that improve clinical outcomes and quality of life for patients with vascular diseases, while also providing physicians with innovative treatment options.

Goop Inc. is a lifestyle brand that operates an online platform focused on wellness, curated shopping, and lifestyle content. Founded in 2008 by Gwyneth Paltrow, Goop originated as a weekly newsletter but has since evolved into a comprehensive lifestyle site. It offers a carefully curated selection of products, including apparel, beauty items, wellness products, and home goods. The platform also provides valuable content, featuring expert advice on health, fitness, and mental well-being, along with travel recommendations, cooking recipes, and design ideas. Goop aims to serve as a trusted resource for readers, presenting insights and suggestions in a personalized manner rather than through anonymous sources. The brand emphasizes clean beauty and wellness, exemplified by its exclusive skincare line, Goop by Juice Beauty, which aligns with its commitment to quality and holistic living. Based in New York, Goop continues to expand its offerings while maintaining a focus on authenticity and expert-driven content.

DataVisor Inc. is a technology company specializing in fraud and financial crime detection through advanced big data solutions. Founded in 2013 and headquartered in Mountain View, California, the company employs unsupervised machine learning to identify and predict attack vectors across various user accounts. Its flagship products include dCube, a proactive fraud management solution that detects known and unknown fraud, and dVector, which provides accurate fraud signals and contextual analysis for effective decision-making. DataVisor also offers dEdge, which gathers real-time intelligence from connected devices to safeguard mobile and web applications against manipulation and threats. The company's solutions address a wide range of issues, including account takeovers, fake accounts, transaction fraud, and content moderation, serving industries such as financial services, e-commerce, social platforms, and telecommunications.

Fire1 is a Dublin-based company dedicated to developing innovative therapeutic devices aimed at enhancing the quality of life for heart failure patients. The company has created a remote monitoring system that delivers real-time patient data and insights to healthcare providers. This technology facilitates the early detection of complications associated with heart failure, allowing for proactive interventions and ultimately leading to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to transform the management of heart failure and support better health management for patients.

Metavention, Inc., founded in 2012 and based in Dover, Delaware, specializes in developing innovative treatments aimed at permanently disrupting the overactive nerves that contribute to high blood pressure and various metabolic diseases. The company has created a renal denervation procedure that employs radio frequency energy to target and modulate overactive sympathetic nerves. This trans-catheter device not only addresses issues related to high blood pressure but also focuses on conditions such as Type 2 diabetes by employing standard interventional vascular techniques. By providing physicians with advanced tools for diagnosis and treatment, Metavention aims to enhance patient outcomes for those suffering from metabolic disorders linked to sympathetic nervous system activity.

ThreatQuotient, Inc. is a company that specializes in developing a threat intelligence platform designed to help organizations manage and respond to cyber threats effectively. Founded in 2013 and headquartered in Reston, Virginia, with additional operations in Germany and Australia, ThreatQuotient offers a platform that integrates and correlates various external intelligence sources with internal security processes and analytics. This platform provides contextual and operationalized intelligence, enabling organizations to streamline their security operations by focusing on prioritized threats. Its features include Indicator Nurturing, which tailors indicators of compromise to specific infrastructures, and the automation of processes to enhance investigation efficiencies and collaboration among security teams. By integrating with existing technologies, ThreatQuotient’s solutions support multiple use cases such as incident response, threat hunting, and vulnerability management. The company has been recognized for its product excellence and leadership in the cybersecurity industry, receiving several awards for its contributions to enhancing security operations.

Eargo, Inc. is a consumer-focused medical device company specializing in the design and sale of hearing aids for individuals with hearing loss in the United States. Founded in 2010 and headquartered in San Jose, California, Eargo offers innovative, rechargeable hearing aids that can be controlled via smartphone, enhancing user convenience. The company provides online hearing screenings and virtual support, eliminating the need for in-person consultations. By adopting a direct-to-consumer model, Eargo aims to make hearing aids more accessible and reduce the social stigma often associated with them. Its user-centric approach addresses the common challenges of traditional hearing aid adoption, including cost and accessibility, thereby improving the quality of life for those with hearing difficulties.

Wheels Up is a membership-based private aviation company that specializes in on-demand flight services in the United States. By leveraging data and technology, it connects consumers with safety-vetted private aircraft, offering both programmatic and charter options. The company aims to reduce the upfront costs associated with private flying while providing flexibility, service, and safety to its members. Through its mobile app, users can easily book flights, manage accounts, and access ride-share opportunities. Additionally, members participate in the Wheels Down program, which enhances their travel experiences. Wheels Up operates a diverse fleet, utilizing owned, leased, and chartered aircraft to provide a wide range of global travel alternatives.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Raise Marketplace Inc. operates an online platform for buying and selling gift cards, allowing users to convert unused cards into cash and purchase discounted gift cards from various brands and categories. The company collaborates with over 600 national brands to enhance customer loyalty and engagement while providing savings and rewards through its Raise Pay service. Since its inception in 2010, Raise has helped millions of members save over $200 million. Additionally, the company offers rZero, a risk minimization service aimed at preventing digital fraud, including account takeovers and counterfeit activities. Based in Chicago, Illinois, Raise is accessible on both iOS and Android devices, as well as through its website.

Amplyx Pharmaceuticals, Inc. is a small molecule drug development company focused on creating innovative therapies for debilitating and life-threatening diseases, particularly those affecting individuals with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in the development of oral and injectable anti-infective drugs, including antifungal agents designed to treat invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by incorporating a second small molecule. This strategy aims to provide effective treatment options for patients undergoing chemotherapy and other immunosuppressive therapies, ensuring they receive appropriate care both during hospitalization and after discharge.

DataRobot, Inc. is a Boston-based company that specializes in developing an automated machine learning platform aimed at empowering enterprises to construct predictive models efficiently. Its offerings include DataRobot Cloud, a cloud-based platform for predictive analytics, and DataRobot MLOps, which facilitates the deployment, monitoring, and management of machine learning models across organizations. Additionally, DataRobot Enterprise provides features tailored for large organizations, such as flexible deployment options, governance, and comprehensive support. The company's solutions cater to a diverse clientele, including business analysts, data scientists, executives, and IT professionals across various sectors such as banking, healthcare, and manufacturing. Founded in 2012, DataRobot has expanded its operations internationally, with locations in London, Paris, Kyiv, Tokyo, and Singapore, and maintains a strategic partnership with Snowflake to enhance its offerings.

Complexa, Inc. is a biopharmaceutical company focused on developing innovative medicines for severe and life-threatening conditions related to fibrosis and inflammation. Founded in 2008 and based in Berwyn, Pennsylvania, the company specializes in researching endogenous human cell signaling technologies to address a range of inflammatory, fibrotic, and central nervous system diseases. Its proprietary technology centers on the synthesis and therapeutic use of endogenous nitro-fatty acids, which serve as cell-signaling agents that modulate key inflammatory pathways. Notable among its developments is CXA-10, an oral nitrated fatty acid compound aimed at treating conditions such as focal segmental glomerulosclerosis and pulmonary arterial hypertension. Through its research efforts, Complexa aims to enhance existing anti-inflammatory and metabolic signaling mechanisms to support the resolution and repair of both acute and chronic tissue injuries.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, established in 2011. The company specializes in the development and commercialization of Haduvio, an oral extended-release formulation of nalbuphine. Haduvio is currently undergoing a Phase IIb/III clinical trial, known as the PRISM trial, aimed at treating chronic pruritus associated with prurigo nodularis. Additionally, Trevi is exploring the use of nalbuphine ER for other serious neurologically mediated conditions, including chronic cough in patients with idiopathic pulmonary fibrosis and levodopa-induced dyskinesia in individuals with Parkinson’s disease. The treatment targets conditions that share a common pathophysiology mediated through opioid receptors in the central and peripheral nervous systems.

Segment.io, Inc. is a company that specializes in customer data infrastructure, enabling businesses to collect, unify, and connect their customer data across various platforms. Founded in 2011 and headquartered in San Francisco, California, Segment offers a single API that allows organizations to track customer information across multiple devices and channels. This data can be seamlessly sent to a variety of third-party tools, internal systems, or SQL databases. Additionally, Segment provides a product known as Data Lakes, which assists companies in leveraging their customer data to enhance user experiences. The company also maintains an office in Dublin, Ireland, and operates as a subsidiary of Twilio Inc. as of November 2020.

Transfix, Inc. is a trucking brokerage firm based in New York, specializing in connecting shippers with carriers for freight transportation across the United States. Founded in 2010, the company has developed an advanced online freight management platform that utilizes AI-driven algorithms to optimize freight matching and enhance supply chain visibility. Transfix offers real-time shipment tracking, alerts, and insights on carrier performance, ensuring efficient and reliable transportation solutions. The company serves a diverse range of industries, including retail, food, beverage, and manufacturing, focusing on creating a sustainable freight ecosystem while minimizing empty miles and improving operational efficiency. Through its Intelligent Freight Platform, Transfix aims to revolutionize supply chain performance and support organizations in achieving their logistics goals.

Nightstar Therapeutics is a clinical-stage gene therapy company based in London, United Kingdom, specializing in the development of innovative one-time treatments for rare inherited retinal diseases. The company is advancing several product candidates, including its lead candidate NSR-REP1, which is in phase 3 clinical development for choroideremia. Additionally, Nightstar is working on NSR-RPGR, currently in phase 2/3 trials for X-linked retinitis pigmentosa, as well as NSR-BEST1. The company is also developing NSR-ABCA4, which is in preclinical development for Stargardt disease. Founded in 2017, Nightstar Therapeutics aims to address significant unmet medical needs in the field of retinal disorders.