New Enterprise Associates

Chaos Industries is a technology company focused on defense and critical industries, developing advanced sensing, detection, and communication capabilities. It leverages Coherent Distributed Networks to enhance sensing, detection, and communication across platforms and emphasizes time synchronization to enable highly mobile, scalable, and cost-efficient systems. The company delivers integrated, software-defined solutions for defense, government, and industrial applications in challenging environments.

Metronome provides billing infrastructure for software companies, facilitating rapid deployment, flexibility, and user-friendly solutions. It enables business and product teams to manage revenue and pricing independently, streamlining workflows and offering customers real-time spending insights.

Abcuro develops immunotherapies targeting autoimmunity and cancer. Founded in 2015, the company uses bioinformatics and ex-vivo validation to uncover novel immune system targets.

Sana Labs is a leader in applying artificial intelligence to enhance educational outcomes through personalized learning. The company collaborates with prominent organizations to develop its innovative learning platform, which leverages advanced machine learning techniques. This platform is designed to empower education companies and integrates seamlessly with various applications, allowing employees to access knowledge, communicate, and automate tasks effectively. By offering insights into team strengths, weaknesses, and progress, Sana enables institutions in sectors such as healthcare, finance, and pharmaceuticals to improve their workforce's performance and learning experiences. The interdisciplinary team at Sana comprises experts from diverse fields, contributing to its mission of transforming the future of education.

Pathos develops an AI-enabled drug discovery platform aimed at reducing the medication development process. Its self-learning platform uses big data, technology, and artificial intelligence to identify targets, validate them, and establish their clinical efficacy, enabling drug developers to explore novel concepts and advance breakthrough therapies for various diseases.

Second Front Systems develops software that facilitates government access to innovative commercial technologies for national security missions. Its flagship product, Atlas Fulcrum, enables identification, assessment, and secure deployment of these technologies. The company also offers program management services and High Technology Council, an enterprise consortium fostering collaboration between market players.

MBX Biosciences is a biotechnology company focused on developing therapies for endocrine and metabolic disorders, emphasizing rare endocrine diseases with limited treatment options. It pursues discovery, development, and commercialization of first-in-class peptide therapeutics that modulate glandular hormone signaling. MBX has developed a proprietary Precision Endocrine Peptide platform to engineer peptides with extended time-action profiles and consistent drug exposure, aiming to overcome limitations of traditional peptide therapies and improve disease management. Based in Carmel, Indiana, the company advances novel peptide programs through clinical development to address unmet medical needs in endocrine and metabolic disorders.

Zenas BioPharma is a clinical-stage biopharmaceutical company focused on developing immune-based therapies for autoimmune and immune-mediated diseases. Based in Florida, United States, the company advances biologic programs and aims to modulate B cell–driven pathology. Its lead product candidate, obexelimab, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb on B cells, thereby inhibiting harmful immune activity without depleting B cells.

Perplexity is an AI-driven search engine platform that combines large language models with traditional search engines. It uses natural language processing (NLP) and generative AI to provide conversational responses, bridging the gap between conventional search engines and interactive AI assistance.

Inkitt operates an online community for writers and readers, offering a platform where authors can share and refine their work while gaining insights from readers. The company uses data-driven approaches to identify popular stories and publishes them across various media, aiming to create blockbuster franchises similar to Disney's model.

Pair Eyewear, Inc. is a New York-based company that specializes in customizable eyeglasses for children. Founded in 2017 by Nathan Kondamuri and Sophia Edelstein, the company offers a unique approach to eyewear by providing base frames and interchangeable top frames that allow kids to express their personal style and interests. By combining functionality with creativity, Pair Eyewear transforms glasses from mere medical devices into a fun and engaging accessory for children. The company's direct-to-consumer model leverages an e-commerce platform, making the purchasing process convenient for parents while enhancing the overall experience for young wearers. Pair Eyewear is committed to offering quality, affordable glasses that are both stylish and practical, featuring hand-polished frames and shatterproof polycarbonate lenses.

Founded in 2017, Pulumi Corporation operates an infrastructure-as-code platform for developing cloud software. It offers Pulumi SDK, an open-source tool enabling developers to create, deploy, and manage cloud applications and infrastructure using code. The company also provides a web console for collaborative delivery and management of cloud apps and infrastructure across public, private, or hybrid environments.

Spyglass Pharma specializes in developing innovative treatments for chronic eye diseases using advanced technologies. The company aims to deliver multiple drugs to address additional ophthalmic indications.

Instabase, Inc. is a technology company based in San Francisco, California, founded in 2015. It specializes in developing a platform that automates document processing workflows and analyzes unstructured data. The platform integrates various capabilities, including optical character recognition, data classification and extraction, and natural language processing, allowing organizations across sectors such as insurance, finance, and healthcare to streamline operations and improve decision-making. Additionally, Instabase provides a developer kit that enables the creation of customized business applications, helping institutions embed artificial intelligence into their systems and processes. Through its innovative solutions, Instabase aims to address significant business challenges and facilitate transformational outcomes for its clients.

Strive Health, LLC is a company focused on providing comprehensive solutions for chronic kidney disease. Founded in 2018 and based in Denver, Colorado, Strive Health operates dialysis centers and employs advanced predictive analytics to enhance patient care. The company offers a high-touch, technology-enabled clinical model that supports patients throughout their healthcare journey, from primary care engagement to dialysis treatment. By utilizing comparative and predictive data, Strive Health aims to identify at-risk patients and transform the management of kidney disease, promoting earlier intervention and increasing the adoption of home dialysis. This innovative approach not only improves patient outcomes but also seeks to reduce inpatient utilization, ultimately enhancing the overall experience for individuals dealing with chronic kidney conditions.

Founded in 2015, Mojo Vision specializes in developing and commercializing advanced micro-LED display technology for various applications. The company is renowned for creating the world's smallest dynamic display for augmented reality smart contact lenses. Headquartered in Saratoga, California, Mojo Vision aims to disrupt the $160 billion display industry with its proprietary quantum-dot technology.

Outrider develops autonomous electric trucks and management software for logistics hubs. Its technology automates yard operations, enhancing safety and efficiency for large enterprises.

Escient Pharmaceuticals, Inc. is a biotechnology company based in San Diego, California, specializing in the development and manufacture of G protein-coupled receptor (GPCR)-targeted drugs aimed at treating neuro-immuno-inflammatory and autoreactive diseases. Founded in 2017, Escient focuses on harnessing the therapeutic potential of specific orphan GPCRs, particularly the Mas-Related G-Protein Receptors (Mrgprs). The company aims to provide innovative therapies for a variety of conditions, including mast cell-mediated disorders and cholestatic pruritus, thereby expanding treatment options for healthcare providers facing these complex diseases.

Inversago Pharma Inc. is a preclinical-stage biotechnology company based in Montreal, Canada, specializing in the development of peripherally-restricted CB1 receptor inverse agonists aimed at treating various metabolic and fibrotic disorders. Founded in 2015, the company focuses on creating innovative therapies for conditions such as Prader-Willi syndrome, diabetes, and complications related to obesity. Its pipeline includes treatments for diabetic kidney disease, non-alcoholic steatohepatitis, and progressive fibrosis, including interstitial lung disease. Inversago Pharma aims to improve patient outcomes by offering new therapeutic options that target the underlying mechanisms of these diseases.

Evident is a global leader in business credentialing, operating in over 100 countries. Its platform connects insurers, enterprises, and businesses, verifying credentials to meet compliance standards using advanced AI technology.

Moximed develops and provides the Atlas System, an implantable joint unloader designed to alleviate pain and preserve mobility in patients with medial compartment knee osteoarthritis. Its outpatient treatment option aims to improve quality of life for those not responsive to other therapies or candidates for knee replacement.

Super is a social commerce platform that enables leaders to become self-made entrepreneurs and builds logistics networks. The company features Superagen, an agent-led commerce group buying that enables community leaders to become retailers within their communities.

Genies empowers individuals to create personalized digital avatars for expression across social media and messaging platforms. It offers tools for users to design avatars, avatar fashion lines, worlds, and interactive experiences, enabling brands to drive engagement through exclusive digital goods.

Built Robotics develops automation technology for the construction industry by turning heavy equipment into autonomous robots with AI-guided software that integrates sensors such as GPS, cameras, and Lidar. The systems retrofit onto earthmoving equipment to enable autonomous operation on job sites, supporting projects such as wind farms, oil and gas pipelines, mining, and housing developments, and they are used to automate repetitive tasks in solar projects to accelerate the transition to clean energy.

Timescale develops an open-source time-series SQL database, TimescaleDB, designed for scale and complex queries. It integrates directly into query planning and execution engines to optimize performance, enabling clients to organize, store, analyze, and interpret time-series and machine data.

Beyond Identity, Inc. is a New York-based company that specializes in cloud-native passwordless identity management solutions. Founded in 2019, it aims to enhance digital security by replacing traditional passwords with secure, X.509-based certificates. This innovative approach creates a robust Chain of Trust, incorporating user and device identity along with a real-time assessment of device security for adaptive authentication and authorization. Beyond Identity's platform facilitates frictionless login experiences through biometric authentication and seamless integration with Single Sign-On (SSO) systems, catering to employees, contractors, and customers alike. By eliminating the use of passwords, the company helps organizations mitigate risks associated with credential-stuffing attacks and streamline their authentication processes, ultimately enabling greater business agility and cost efficiency.

FTX is a cryptocurrency exchange company that develops platforms for professional trading firms, offering intuitive interfaces suitable for both experienced traders and beginners. It supports quarterly and perpetual futures for all major cryptocurrencies, leveraged tokens, and OTC derivatives.

Founded in 2012, Virtru specializes in data security solutions. Its platform enables businesses to protect sensitive information throughout its lifecycle without compromising ease of use, supporting compliance and maintaining control over data.

InCarey is a Shanghai-based company founded in 2011 that specializes in developing a comprehensive medical service platform focused on the management of chronic and vertical diseases. The platform integrates medical, pharmaceutical, and insurance resources to provide a one-stop solution for patients requiring long-term care and support. InCarey's cloud-based online platform facilitates professional disease management services, allowing for direct interaction between doctors and patients. Additionally, it includes an e-commerce component that enables users to conveniently access medications for various chronic conditions. The company is dedicated to enhancing the patient experience through innovative payment services and a holistic approach to chronic disease management.

Founded in 2017, Forethought Technologies develops AI models for question-answering and information retrieval, embedding them into employee workflows. Its flagship product, Agatha Answers, is a smart agent that enhances customer support teams' efficiency by resolving common queries instantly.

Anyscale develops and operates distributed programming platforms for simplifying distributed AI development. It offers Ray, an open-source framework enabling software developers and machine learning engineers to scale applications effortlessly from a laptop to the cloud.

Block Renovation operates a renovation platform that unites design, sourcing, and construction within a single process to simplify home makeovers. The company combines architect-grade design, construction labor, and materials into a streamlined experience, enabling homeowners to plan, design, and build renovations with greater certainty around outcomes, quality, price, and timeline. By integrating design, sourcing, and project management under one roof, Block Renovation aims to improve the renovation journey for homeowners and provide contractors with a clearer, more efficient workflow.

Stride Health, Inc. is a health benefits platform that specializes in providing affordable health coverage options for independent workers and part-time employees in the United States. The company offers a range of services, including dental plans, doctor and prescription insurance plans, and various health coverage options tailored to meet the needs of its customers. Stride Health simplifies the enrollment process by guiding users through selecting the most cost-effective health plans, aiming to optimize their tax benefits and enhance their take-home pay. Founded in 2013 and based in San Francisco, California, the company was previously known as Covered, Inc. and rebranded to Stride Health, Inc. in March 2013. Stride Health also provides personal advisory services to assist clients in navigating the complexities of their health insurance options.

Founded in 2013, Clarifai specializes in advanced image recognition systems for detecting near-duplicates and enabling visual search. Its platform recognizes various categories, objects, and tags in images, and finds similar images in large uncategorized repositories using a combination of semantic and visual similarity.

Sisu is a decision intelligence engine that allows users to efficiently and comprehensively utilize their cloud data. Companies such as Mastercard, Autodesk, Samsung, Upwork, Wayfair, Equinox, Udacity, and Gusto leverage Sisu to enhance their customer experiences, increase revenue growth, and reduce incident rates.

Pager, Inc. is a company that operates an on-demand service platform designed to connect patients with healthcare services in various settings including homes, offices, and hotels. The company offers a mobile application that facilitates access to urgent care for a range of conditions such as infections, respiratory issues, and allergies. In addition to its core services, Pager provides nurse chat, teleconsultation, screening, vaccination, and prescription delivery. The company's mission focuses on improving healthcare accessibility, lowering costs, and simplifying care navigation through a flexible platform that integrates artificial intelligence and service teams. Amidst its extensive offerings, Pager supports over 15 million individuals across the United States and Latin America, enabling coordinated care that enhances patient engagement and decision-making. Incorporated in 2013 and headquartered in New York, Pager was previously known as techCare, Inc. before rebranding in 2014.

Allay Therapeutics is pioneering ultra-sustained pain therapeutics to transform post-surgical pain management. Its proprietary platform combines non-opioid analgesics and biopolymers to create dissolvable therapeutics delivering pain relief within targeted sites over weeks, significantly longer than current treatments. The company's lead product candidate, ATX101, is in Phase 2 clinical trials for total knee replacement surgeries.

Tulip Interfaces is a technology company that creates shop‑floor applications for the manufacturing sector. Its no‑code platform integrates sensor data, digital work instructions, real‑time visualization, and operator inputs to connect existing equipment and streamline operations. The solution is used by firms in consumer electronics, pharmaceuticals, apparel, medical devices, aerospace, defense, automotive, and contract manufacturing to improve productivity, quality, and operational visibility. Founded in 2012, the company is headquartered in Somerville, Massachusetts.

ARRIS specializes in developing additive molding technology for manufacturing large-scale 3D-aligned continuous fiber thermoplastic composite parts. Its innovative process combines aligned fibers, electronics, and metallic components within topology-optimized structures, serving industries such as aerospace, automotive, and consumer products.

Aetion is a New York‑based company that builds a real‑world evidence platform. It aggregates claims, electronic health records, registries and clinical trial data to generate analytics that help payers, providers, biopharma and medical device firms assess the effectiveness and value of treatments. The platform’s rapid‑cycle analytics enable real‑time collaboration between payers, providers and life‑science companies, supporting value‑based care decisions. Founded in 2012 by Harvard Medical School faculty and data scientists, it has partnerships with McKesson and receives backing from major venture investors. The platform is used worldwide by health‑economists, epidemiologists and biostatisticians for database analytics and comparative‑effectiveness research.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Arcellx is a clinical-stage biotechnology company developing immunotherapies and cell therapies for cancer and other serious diseases. It seeks to make cell therapies safer, more effective, and more broadly accessible. Its lead candidate CART-ddBCMA is in a Phase 1 trial for relapsed or refractory multiple myeloma and has FDA Fast Track, Orphan Drug, and Regenerative Medicine Advanced Therapy designations. The company is also advancing ARC-SparX, a dosable and controllable CAR-T platform, into clinical programs ACLX-001 for relapsed or refractory multiple myeloma and ACLX-002 for relapsed or refractory acute myeloid leukemia. Arcellx's pipeline covers multiple myeloma, acute myeloid leukemia, and other cancer indications, with research extending into additional oncology areas and other serious diseases.

Cleo Labs, Inc. is a family support platform that offers pregnancy consultancy and parenthood guidance services to working parents. The company provides a range of consultation services, including lactation support, birth preparation, child wellness, and sleep consulting, as well as career coaching and immediate post-birth assistance. Cleo's mobile application connects families with certified care practitioners, facilitating their journey from fertility through parenting children up to age five. By partnering with employers, Cleo aims to enhance workplace culture, improve employee retention, and foster diverse and inclusive environments. The company operates globally, serving clients in over 50 countries and has collaborated with notable organizations such as eBay and LinkedIn. Founded in 2016 and headquartered in San Francisco, Cleo was previously known as Instacare Group, Inc. before rebranding in 2018.

Monte Rosa Therapeutics is a biotechnology company focused on cancer therapeutics that target protein degradation pathways. It specializes in developing molecular glue degraders, a class of small molecules that direct disease-relevant proteins to degradation by the cell's natural machinery. The company uses its QuEEN platform, incorporating artificial intelligence and proprietary experimental tools, to identify target proteins for degradation by molecular glue degraders. It maintains a diverse library of more than 50,000 molecules and advancing its pipeline, including MRT-2359, a candidate that targets the translation termination factor GSPT1 for potential use in MYC-driven tumors.

Nuvolo Technologies Corporation offers a cloud-based enterprise asset management platform designed to support the lifecycle management of assets in various sectors, including healthcare, manufacturing, and facilities management. Founded in 2013 and headquartered in Paramus, New Jersey, Nuvolo innovates on the ServiceNow platform to provide a user-friendly experience for mobile and online users. The company’s solutions encompass implementation, support, tracking, reporting, and analytics, aimed at optimizing operational efficiency and improving asset management. Nuvolo also emphasizes security, workflow automation, and accurate inventory data, making it a comprehensive choice for businesses looking to enhance their asset management capabilities. With additional offices in London, Sofia, and Pune, Nuvolo maintains a global presence through strategic partnerships with firms such as KPMG and Unisys.

Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.

Personal Genome Diagnostics, Inc. is a biotechnology company focused on patient-specific analyses of cancer genomes. Established in 2010 and headquartered in Baltimore, Maryland, the company has pioneered technologies for non-invasive "liquid biopsy" approaches, allowing for the detection of tumor-specific alterations in circulating cell-free DNA. Its offerings include the METDetect Assay for identifying MET gene amplifications, LungSelect for detecting actionable genetic alterations in non-small cell lung cancer patients, and PGDx elio plasma resolve, which analyzes various genetic mutations from plasma samples. Additionally, Personal Genome Diagnostics provides RNAcomplete, enabling researchers to extract both RNA and genomic DNA from a single tissue sample, and CancerXOME, which captures and analyzes coding regions of genes. The company collaborates with institutions like Mayo Clinic and partners with KingMed Diagnostics to enhance its research and diagnostic capabilities, thereby empowering oncologists and researchers with crucial genomic insights to combat cancer.

Sitetracker is a SaaS platform optimizing critical infrastructure lifecycle management. It enables efficient planning, deployment, maintenance, and growth of capital asset portfolios via AI, automation, and analytics.

KONUX GmbH is a German company based in Munich, founded in 2014, that specializes in developing Industrial Internet of Things (IIoT) solutions for railway and industrial applications. The company integrates smart sensor systems with artificial intelligence-driven analytics to provide real-time monitoring of asset and infrastructure conditions, enabling predictive maintenance and enhancing operational efficiency. KONUX's offerings include switch monitoring, asset monitoring, rolling stock monitoring, anomaly detection, and customized hardware solutions. By leveraging machine learning and IoT technologies, KONUX aims to transform railway operations, making them more sustainable, reliable, and cost-effective. The company has expanded its footprint across Europe and Asia and has gained recognition as one of the most innovative startups globally, underscoring its commitment to modernizing transportation systems.

Bestow Inc., established in 2016 and based in Dallas, Texas, operates as a digital life insurance company. It provides life insurance services to individuals, leveraging data-driven technology applications and algorithmic underwriting to assess risks efficiently. The company partners with top carriers to enhance processes from origination to administration, aiming to increase financial stability for all.

Alfred Club, Inc. is a technology-driven company that provides a resident experience and building management platform designed for apartment buildings. Founded in 2013 and based in New York, Alfred offers the Hello Alfred program, which allows residents to outsource everyday tasks such as package receiving and dog walking to dedicated home managers. These home managers are W-2 employees, ensuring they receive benefits and training, which enhances service quality and fosters local community support. The platform integrates various services, enabling residents to request assistance with grocery delivery, home cleaning, and access to exclusive events and virtual classes, all through a single, intuitive interface. Alfred has been recognized as a leader in transforming the real estate industry and has gained media attention for its innovative approach to enhancing the residential living experience.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Everactive develops ultra-low-power chips for battery-less wireless sensors, enabling end-to-end IoT data services. Its solutions provide low-cost, long-lived, intelligent instrumentation for industrial operations across various applications.

Amplyx Pharmaceuticals, Inc. is a small molecule drug development company focused on creating innovative therapies for debilitating and life-threatening diseases, particularly those affecting individuals with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in the development of oral and injectable anti-infective drugs, including antifungal agents designed to treat invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by incorporating a second small molecule. This strategy aims to provide effective treatment options for patients undergoing chemotherapy and other immunosuppressive therapies, ensuring they receive appropriate care both during hospitalization and after discharge.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

ChromaCode Inc., established in 2012 and based in Carlsbad, California, specializes in molecular diagnostics. The company develops innovative testing solutions for infectious diseases, cancer, and non-invasive prenatal testing (NIPT) using technology licensed from Caltech. ChromaCode's core products are software, reagents, and assays that enhance the multiplexing capabilities of quantitative PCR (qPCR) instruments by fivefold. Additionally, they offer molecular assays and software for various applications such as personalized medicine and pharmaceutical research. One of their notable products is the HDPCR Tick-Borne Pathogen Panel, a multiplex PCR test detecting common tick-borne pathogens in a single assay. ChromaCode's technology focuses on improving signal processing from life science instrumentation, enabling cost-effective testing of multiple targets simultaneously while integrating into existing laboratory workflows.

Black Diamond Therapeutics discovers and develops small molecule therapies for precision oncology. It focuses on allosteric mutations in kinases related to cancer, with a lead product candidate targeting non-canonical ErbB kinase mutations.

Sentry is an open-source platform focused on improving workflow productivity by monitoring application performance and error reporting. The company provides a tool that captures real-time data on errors and crashes within software applications, allowing users to prioritize and identify issues as they occur. This tool offers detailed insights into deployments and assists in reproducing and fixing crashes, enabling organizations to understand which errors are most detrimental to their operations. By highlighting the impact of these issues on business performance, Sentry helps its clients enhance their software reliability and ultimately improve their bottom line.

PlayVS operates a platform that organizes and facilitates online esports tournaments and wagers for cash prizes among high school students. It enables teen gamers to form teams, compete with other schools, and vie for state championship titles.

Echodyne, established in 2014 and based in Kirkland, Washington, specializes in developing and marketing metamaterials-based radar systems. The company offers a range of radar solutions, including 3D Security radar for all-weather, compact, and solid-state sensor performance; Metamaterial Electronically Scanning Array (MESA) technology for high-performance phased-array radar at breakthrough cost levels; and Echoguard for ground-based airspace management. Additionally, Echodyne provides Acuity Software for customization and data processing, along with various deployment kits and accessories. Their products cater to commercial markets, government, defense, and industry, enabling autonomous applications in drones, vehicles, and heavy machinery, even in complex and challenging environments.

Heap Inc. is a company that develops an analytics infrastructure designed for online businesses, enabling them to capture and analyze customer interactions across web, mobile, and cloud platforms. Founded in 2012 and headquartered in San Francisco, California, Heap's solution automates the collection and organization of customer behavioral data, such as clicks, transactions, and form submissions, without requiring additional coding. This streamlined approach allows businesses to gain a comprehensive understanding of their users, facilitating informed decision-making and enhancing product development. Heap serves a diverse range of industries, including e-commerce, financial services, and SaaS, with over 6,000 clients that include notable companies across various sectors. The company is committed to empowering organizations to focus on insights and actions that drive business success.

Expel, Inc. is a cybersecurity company that specializes in managed security software and services. Founded in 2016 and based in Herndon, Virginia, Expel offers a comprehensive security operations center (SOC)-as-a-service, which includes managed detection and response (MDR), threat hunting, remediation, and phishing support. The company’s platform, known as the Expel Workbench™, facilitates a collaborative experience, allowing customers to engage actively in their security operations. Users can monitor live investigations or receive detailed alerts throughout the investigative process. Expel’s approach emphasizes transparency and efficiency, enabling security teams to focus on strategic priorities while swiftly addressing threats such as ransomware, phishing, and supply chain attacks. With dedicated analysts available around the clock, Expel aims to enhance organizations' security posture by swiftly identifying and mitigating risks while reducing the noise of false positives.

Tamara Mellon is a women’s fashion brand that designs and markets shoes, handbags, and ready-to-wear apparel. Its product range includes sandals, boots, pumps, flats, and legging boots, along with dresses, jumpsuits, tops, knitwear, pants, skirts, jackets and outerwear, and related accessories. The company sells through its own retail stores and online channels in the United States and internationally. Founded in 2011 by Tamara Mellon and Jill Layfield, it is headquartered in New York City.

Expanse, Inc. is an enterprise software company based in San Francisco, California, specializing in data marshalling services to enhance the security and management of global internet assets. Founded in 2012 and formerly known as Qadium, Inc., the company provides an innovative platform that offers organizations an updated view of their internet-connected assets. This platform enables IT and security teams to gain visibility into their global internet attack surface, identifying unknown assets and managing exposure to online threats. Expanse's technology indexes global IP addresses, DNS protocol information, and registration records, allowing organizations to improve governance and IT operations while minimizing risks associated with their internet presence. Trusted by major enterprises and government agencies, Expanse monitors and tracks over 400 million internet- and cloud-connected assets, representing more than 10% of the global Internet, to enhance awareness and prevent successful cyberattacks.

Igneous Systems, Inc., founded in October 2013 and headquartered in Seattle, Washington, specializes in enterprise data center infrastructure and unstructured data management. The company offers a comprehensive as-a-Service solution that provides businesses with visibility, protection, and mobility for their unstructured data on a large scale. Igneous’s cloud-native, API-enabled platform integrates various unstructured data management functions, allowing organizations to maximize the value of their data while minimizing risks and optimizing IT resource utilization. Its services include consolidated backup, file system archiving, and efficient management of unstructured data, all aimed at enhancing workflow productivity for data-centric enterprises.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, established in 2011. The company specializes in the development and commercialization of Haduvio, an oral extended-release formulation of nalbuphine. Haduvio is currently undergoing a Phase IIb/III clinical trial, known as the PRISM trial, aimed at treating chronic pruritus associated with prurigo nodularis. Additionally, Trevi is exploring the use of nalbuphine ER for other serious neurologically mediated conditions, including chronic cough in patients with idiopathic pulmonary fibrosis and levodopa-induced dyskinesia in individuals with Parkinson’s disease. The treatment targets conditions that share a common pathophysiology mediated through opioid receptors in the central and peripheral nervous systems.

The Wing is a network of work and community spaces designed specifically for women, with locations in New York, California, and Washington, D.C. The organization aims to foster the professional, civic, social, and economic advancement of women by providing a supportive environment. Its facilities include open-plan workspaces, meeting rooms, phone booths, and an extensive library curated for women. The Wing creates a community of professional women, facilitating connections and support among female founders, thereby inspiring and empowering them to grow their businesses and achieve their goals.

Annexon Biosciences is a clinical-stage biopharmaceutical company focused on developing novel therapies for patients with classical complement-mediated disorders affecting the body, brain, and eye. The company's pipeline is built on a platform technology that targets well-researched autoimmune and neurodegenerative disease processes triggered by the aberrant activation of C1q, the initiating molecule of the classical complement pathway. Annexon's lead product candidate, ANX005, is a full-length monoclonal antibody designed for intravenous administration to treat autoimmune and neurodegenerative disorders. Another key candidate, ANX007, is a monoclonal antibody Fab formulated for intravitreal administration to address neurodegenerative ophthalmic disorders. The company employs a biomarker-driven development strategy to ensure that its product candidates effectively engage the target at therapeutic doses within the intended patient tissue, while also exploring additional orphan and large market indications.

Plaid is a technology platform that provides APIs and developer tools to connect consumer bank accounts and financial data with applications. It enables developers to build modern financial services by offering infrastructure and intelligence tools that allow access to transactions, authentication for bank accounts, identity verification, real-time balances, asset verification, and income data. Its products include Transactions, Auth, Identity, Balance, Assets, and Income, supporting personal finance, consumer payments, lending, banking and brokerage, and business finance solutions. Plaid serves developers from startups to large financial institutions, helping democratize financial services with a developer-friendly experience. The company was founded in 2012 and is headquartered in San Francisco, California.

NeueHealth is a healthcare company dedicated to providing high-quality, coordinated care to aging and underserved populations. It operates through two segments: NeueCare, which manages risk in partnership with external payors, serving diverse patient populations; and NeueSolutions, offering technology, services, and clinical care solutions to empower providers.

Infoworks.io, Inc. is an enterprise software company that specializes in automated data management solutions for organizations seeking to optimize their cloud data operations. Founded in 2014 and headquartered in Palo Alto, California, with an additional office in Bengaluru, India, Infoworks offers its flagship product, DataFoundry, which facilitates the discovery, loading, organization, and management of data on Hadoop. The platform supports data operations and orchestration, enabling organizations to streamline workflows from data ingestion to analytics in various environments, including cloud, multi-cloud, and hybrid settings. Infoworks' solutions encompass data ingestion, synchronization, preparation, cube generation, and workflow management, significantly accelerating cloud migration processes and modernizing data operations while reducing costs. By enhancing agility and scalability, Infoworks empowers enterprises to leverage their data for advanced analytics, artificial intelligence, and machine learning applications more efficiently.

HEAVY.AI develops a big data analytics and visualization platform that helps governments and businesses analyze and visualize opportunities and risks hidden in large location- and time-based datasets. The platform combines a structured query language–compliant database optimized for graphics processing units with an advanced visual analytics engine and a web-based front end for rendering multi-billion-record data sets. By leveraging the parallel processing power of modern GPU and CPU hardware, it supports high-impact decision-making across sectors such as government, telecommunications, energy, utilities, and higher education.

Galera Therapeutics is a clinical-stage biopharmaceutical company focused on developing therapeutics to mitigate radiotherapy-induced side effects in cancer patients. Its lead product candidate, avasopasem manganese (GC4419), is a small molecule superoxide dismutase mimetic currently in Phase III trials for treating radiation-induced severe oral mucositis in head and neck cancer patients.

Enigma Technologies, Inc. is an operational data management and intelligence company based in New York. It specializes in providing a searchable database of public records, information, and documents, facilitating streamlined operations and informed decision-making for its users. The company offers a suite of products, including Enigma Data Infrastructure, which features tools for data operations and metadata enhancement, and Enigma Solutions, tailored for specific industries such as financial services, pharmacovigilance, and insurance. Enigma also provides analysis-ready public data relevant to sectors like oil and gas, healthcare, and company reference data. Additionally, Enigma operates Enigma Labs, which focuses on developing open data tools for public use, and offers an API to support developers in creating data-rich applications. The company is recognized for its contributions to small business intelligence, delivering timely and accurate insights on the identity and risk profile of small businesses, thus aiding firms in areas such as insurance risk assessment and fraud prevention. Enigma Technologies was incorporated in 2011.

StreamSets, Inc. is a developer of a cloud-based DataOps platform that facilitates modern data integration for enterprises, enabling the continuous flow of big, streaming, and traditional data into data science and analytics applications. Founded in 2014 and headquartered in San Francisco, California, the company offers solutions such as StreamSets Control Hub for designing and monitoring data pipelines, StreamSets Data Collector as an open-source execution engine for managing both streaming and batch data, and StreamSets Transformer for building data transformations across various sources. The platform supports diverse use cases, including integration for data lakes and warehouses, cloud data storage adoption, and the powering of real-time applications. StreamSets serves enterprise clients both in the United States and internationally, with additional offices in locations including Sunnyvale, Austin, London, Barcelona, Bengaluru, and Sydney.

MORE Health, Inc. is a healthcare technology company that has developed a cloud-based physician collaboration platform to facilitate joint diagnosis and treatment planning between attending doctors and specialists. Founded in 2013 and based in Foster City, California, the platform integrates a clinical database containing medical histories, hospital records, lab results, and medical images, along with secure communication tools for real-time discussions. MORE Health offers a variety of services, including a patient portal for personal health records, an Overseas Co-Diagnosis service for international patients, and a Secure Medical Record service for traveling employees. Initially launched as a concierge service for private clients, it now serves U.S. companies as a supplemental health benefit, providing employees access to top-tier medical expertise during serious health issues. With strategic alliances with prominent medical institutions, MORE Health aims to become a virtual global hospital for serious illnesses, ensuring patients receive the highest quality of diagnosis and treatment when needed.

Brandless is an omnichannel consumer platform and online marketplace based in San Francisco. Founded in 2015, it offers a broad range of products across groceries and pantry items, home goods, beauty and personal care, health and wellness, baby care, and pet products. The company emphasizes better-for-you and better-for-all products and seeks to empower shoppers to make thoughtful, responsible choices through quality ingredients, responsible sourcing, and community-driven validation. It pursues a collaborative approach, prioritizing people over promotion and focused on creating a mission-driven marketplace that supports simpler, more intentional shopping across multiple channels.

Tuya is a global developer platform specializing in artificial intelligence and the Internet of Things (IoT). It connects consumers, manufacturers, OEMs, and retail chains, providing a comprehensive solution that includes hardware access, cloud services, and app development. This ecosystem enables businesses to enhance their consumer IoT smart devices and meet increasing consumer demands. As of late 2018, Tuya had served 93,000 customers and connected over 100 million smart products globally, with a product catalog exceeding 30,000 listings across nearly 200 countries. The company operates a distributed IoT cloud platform that processes nearly 50 billion device requests daily and facilitates over 20 million voice AI interactions each day, accumulating a data volume of 15 petabytes. Tuya's offerings include platform-as-a-service and software-as-a-service options, fostering a vibrant IoT ecosystem that encourages collaboration among brands, OEMs, partners, and end users.

Framebridge, Inc. specializes in providing custom framing solutions for art and photographs through an online platform. Founded in 2013 and headquartered in Washington, D.C., the company simplifies the traditionally cumbersome and costly custom framing process. Customers can select from a curated range of contemporary frame styles, upload their images directly on the website, or send physical items in prepaid packaging for framing. Framebridge's expert team handcrafts each frame to meet the specific requirements of the customer, ensuring high-quality results. The finished products are then shipped directly to consumers, typically within days and ready for display. The company's pricing is transparent and based on the size of the framed item, starting at $39 and inclusive of free shipping. Framebridge aims to make custom framing accessible and efficient, enhancing the overall customer experience.

Nginx, established in 2011, is a technology company that specializes in developing and maintaining the open-source web server NGINX. Its offerings include application delivery, load balancing, security, and API management solutions. Key products are NGINX Plus, a software load balancer and web server; NGINX Controller, for managing NGINX Plus; NGINX Unit, a dynamic application server; NGINX Web Application Firewall; and NGINX Amplify, a SaaS monitoring tool. Headquartered in San Francisco, with offices in Cork and Singapore, Nginx operates as a subsidiary of F5 Networks.

Metacrine, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, established in 2014. It specializes in the discovery and development of innovative therapies aimed at treating liver and gastrointestinal diseases. The company is advancing a pipeline of drug candidates, with a primary focus on the farnesoid X receptor (FXR), a key target in managing various liver and GI disorders. Its lead candidates, MET409 and MET642, are currently in clinical trials to evaluate their efficacy in treating non-alcoholic steatohepatitis. Additionally, Metacrine collaborates with Novo Nordisk A/S to explore further research opportunities related to fibroblast growth factor 1. The company is committed to developing best-in-class therapies to improve patient outcomes in these challenging medical areas.

XSKY Data Technology, based in Beijing, specializes in software-defined infrastructure products and services. It offers a range of storage solutions, including XCBS (cloud), XEBS (block), XEUS (unified), XEOS (object), and XEDP (unified data platform), catering to diverse sectors such as finance, telecom, energy, and government. XSKY is a significant contributor to the open-source Ceph storage system, ranking top 3 globally. It partners with leading tech companies like Intel and Samsung, providing scalable, cost-effective storage solutions tailored for enterprise needs.

Intact Vascular, Inc. is a medical device company based in Wayne, Pennsylvania, specializing in the development of minimally invasive products for peripheral vascular procedures. Founded in 2011, the company is known for its Tack Endovascular System, which aims to enhance the results of peripheral balloon angioplasty in treating peripheral arterial disease (PAD) and critical limb ischemia (CLI). Intact Vascular focuses on creating safe and effective solutions that improve clinical outcomes and quality of life for patients with vascular diseases, while also providing physicians with innovative treatment options.

Goop Inc. is a lifestyle brand that operates an online platform focused on wellness, curated shopping, and lifestyle content. Founded in 2008 by Gwyneth Paltrow, Goop originated as a weekly newsletter but has since evolved into a comprehensive lifestyle site. It offers a carefully curated selection of products, including apparel, beauty items, wellness products, and home goods. The platform also provides valuable content, featuring expert advice on health, fitness, and mental well-being, along with travel recommendations, cooking recipes, and design ideas. Goop aims to serve as a trusted resource for readers, presenting insights and suggestions in a personalized manner rather than through anonymous sources. The brand emphasizes clean beauty and wellness, exemplified by its exclusive skincare line, Goop by Juice Beauty, which aligns with its commitment to quality and holistic living. Based in New York, Goop continues to expand its offerings while maintaining a focus on authenticity and expert-driven content.

DataVisor Inc. is a technology company specializing in fraud and financial crime detection through advanced big data solutions. Founded in 2013 and headquartered in Mountain View, California, the company employs unsupervised machine learning to identify and predict attack vectors across various user accounts. Its flagship products include dCube, a proactive fraud management solution that detects known and unknown fraud, and dVector, which provides accurate fraud signals and contextual analysis for effective decision-making. DataVisor also offers dEdge, which gathers real-time intelligence from connected devices to safeguard mobile and web applications against manipulation and threats. The company's solutions address a wide range of issues, including account takeovers, fake accounts, transaction fraud, and content moderation, serving industries such as financial services, e-commerce, social platforms, and telecommunications.

FIRE1 is an Irish-based company specializing in the development of innovative therapeutic devices. Its flagship product is a remote monitoring system designed to enhance heart failure patients' lives by providing real-time data to healthcare providers, facilitating early detection and proactive interventions.

Metavention, Inc., founded in 2012 and based in Dover, Delaware, specializes in developing innovative treatments aimed at permanently disrupting the overactive nerves that contribute to high blood pressure and various metabolic diseases. The company has created a renal denervation procedure that employs radio frequency energy to target and modulate overactive sympathetic nerves. This trans-catheter device not only addresses issues related to high blood pressure but also focuses on conditions such as Type 2 diabetes by employing standard interventional vascular techniques. By providing physicians with advanced tools for diagnosis and treatment, Metavention aims to enhance patient outcomes for those suffering from metabolic disorders linked to sympathetic nervous system activity.

Founded in 2013, ThreatQuotient develops a threat intelligence platform that centralizes management of external sources with internal security solutions. Its platform integrates with various tools for contextual intelligence and automates processes to improve efficiency and effectiveness of security operations.

Eargo, Inc. is a consumer-focused medical device company specializing in the design and sale of hearing aids for individuals with hearing loss in the United States. Founded in 2010 and headquartered in San Jose, California, Eargo offers innovative, rechargeable hearing aids that can be controlled via smartphone, enhancing user convenience. The company provides online hearing screenings and virtual support, eliminating the need for in-person consultations. By adopting a direct-to-consumer model, Eargo aims to make hearing aids more accessible and reduce the social stigma often associated with them. Its user-centric approach addresses the common challenges of traditional hearing aid adoption, including cost and accessibility, thereby improving the quality of life for those with hearing difficulties.

Wheels Up is a membership-based private aviation company that specializes in on-demand flight services in the United States. By leveraging data and technology, it connects consumers with safety-vetted private aircraft, offering both programmatic and charter options. The company aims to reduce the upfront costs associated with private flying while providing flexibility, service, and safety to its members. Through its mobile app, users can easily book flights, manage accounts, and access ride-share opportunities. Additionally, members participate in the Wheels Down program, which enhances their travel experiences. Wheels Up operates a diverse fleet, utilizing owned, leased, and chartered aircraft to provide a wide range of global travel alternatives.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Raise Marketplace Inc. operates an online platform for buying and selling gift cards, allowing users to convert unused cards into cash and purchase discounted gift cards from various brands and categories. The company collaborates with over 600 national brands to enhance customer loyalty and engagement while providing savings and rewards through its Raise Pay service. Since its inception in 2010, Raise has helped millions of members save over $200 million. Additionally, the company offers rZero, a risk minimization service aimed at preventing digital fraud, including account takeovers and counterfeit activities. Based in Chicago, Illinois, Raise is accessible on both iOS and Android devices, as well as through its website.

Amplyx Pharmaceuticals, Inc. is a small molecule drug development company focused on creating innovative therapies for debilitating and life-threatening diseases, particularly those affecting individuals with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in the development of oral and injectable anti-infective drugs, including antifungal agents designed to treat invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by incorporating a second small molecule. This strategy aims to provide effective treatment options for patients undergoing chemotherapy and other immunosuppressive therapies, ensuring they receive appropriate care both during hospitalization and after discharge.

DataRobot develops an automated machine learning platform that enables users across various industries to build predictive models. Its cloud-based solution, DataRobot Cloud, offers a project-based curriculum for gaining insights from data scientists. The company also provides DataRobot MLOps for deploying and managing machine learning models, along with enterprise features like flexible deployment and governance in its DataRobot Enterprise solution.

Complexa, Inc. is a biopharmaceutical company focused on developing innovative medicines for severe and life-threatening conditions related to fibrosis and inflammation. Founded in 2008 and based in Berwyn, Pennsylvania, the company specializes in researching endogenous human cell signaling technologies to address a range of inflammatory, fibrotic, and central nervous system diseases. Its proprietary technology centers on the synthesis and therapeutic use of endogenous nitro-fatty acids, which serve as cell-signaling agents that modulate key inflammatory pathways. Notable among its developments is CXA-10, an oral nitrated fatty acid compound aimed at treating conditions such as focal segmental glomerulosclerosis and pulmonary arterial hypertension. Through its research efforts, Complexa aims to enhance existing anti-inflammatory and metabolic signaling mechanisms to support the resolution and repair of both acute and chronic tissue injuries.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, established in 2011. The company specializes in the development and commercialization of Haduvio, an oral extended-release formulation of nalbuphine. Haduvio is currently undergoing a Phase IIb/III clinical trial, known as the PRISM trial, aimed at treating chronic pruritus associated with prurigo nodularis. Additionally, Trevi is exploring the use of nalbuphine ER for other serious neurologically mediated conditions, including chronic cough in patients with idiopathic pulmonary fibrosis and levodopa-induced dyskinesia in individuals with Parkinson’s disease. The treatment targets conditions that share a common pathophysiology mediated through opioid receptors in the central and peripheral nervous systems.

Segment.io, Inc. is a company that specializes in customer data infrastructure, enabling businesses to collect, unify, and connect their customer data across various platforms. Founded in 2011 and headquartered in San Francisco, California, Segment offers a single API that allows organizations to track customer information across multiple devices and channels. This data can be seamlessly sent to a variety of third-party tools, internal systems, or SQL databases. Additionally, Segment provides a product known as Data Lakes, which assists companies in leveraging their customer data to enhance user experiences. The company also maintains an office in Dublin, Ireland, and operates as a subsidiary of Twilio Inc. as of November 2020.

Transfix, Inc. is a trucking brokerage firm based in New York, specializing in connecting shippers with carriers for freight transportation across the United States. Founded in 2010, the company has developed an advanced online freight management platform that utilizes AI-driven algorithms to optimize freight matching and enhance supply chain visibility. Transfix offers real-time shipment tracking, alerts, and insights on carrier performance, ensuring efficient and reliable transportation solutions. The company serves a diverse range of industries, including retail, food, beverage, and manufacturing, focusing on creating a sustainable freight ecosystem while minimizing empty miles and improving operational efficiency. Through its Intelligent Freight Platform, Transfix aims to revolutionize supply chain performance and support organizations in achieving their logistics goals.

Nightstar Therapeutics is a clinical-stage gene therapy company based in London, United Kingdom, specializing in the development of innovative one-time treatments for rare inherited retinal diseases. The company is advancing several product candidates, including its lead candidate NSR-REP1, which is in phase 3 clinical development for choroideremia. Additionally, Nightstar is working on NSR-RPGR, currently in phase 2/3 trials for X-linked retinitis pigmentosa, as well as NSR-BEST1. The company is also developing NSR-ABCA4, which is in preclinical development for Stargardt disease. Founded in 2017, Nightstar Therapeutics aims to address significant unmet medical needs in the field of retinal disorders.