New Enterprise Associates

Chaos Industries is a technology company specializing in next-generation solutions for defense and critical industries. The company is dedicated to enhancing sensing, detection, and communication capabilities through the use of Coherent Distributed Networks (CDN). Its focus on detection and radar services supports the development of advanced defense products, allowing clients to access high-quality services tailored to their needs.

Metronome is a billing infrastructure company that specializes in supporting software companies with usage-based business models. The company's platform provides metering and data mediation software, ensuring a robust data infrastructure and real-time architecture for effective billing. Metronome emphasizes rapid deployment and user-friendliness, allowing business and product teams to manage revenue and pricing with minimal engineering effort. After integrating the platform, teams can swiftly introduce new products and pricing structures, streamline revenue workflows, and offer customers immediate visibility into their spending. This flexibility enables companies to efficiently launch, iterate, and scale their operations.

Abcuro, Inc. is a biotechnology company focused on developing immunotherapies for the treatment of autoimmunity and cancer. Based in Newton, Massachusetts, Abcuro creates therapeutic antibodies targeting novel mechanisms related to these diseases. The company utilizes advanced bioinformatics to analyze transcription data from human diseases, which aids in the identification of new therapeutic targets. Through ex-vivo validation in diseased tissues, Abcuro seeks to uncover innovative methods to modulate key components of the immune system. Established in 2015, Abcuro aims to enhance treatment strategies in the healthcare industry by offering effective solutions for complex immunological conditions.

Sana is an AI company building AI for enterprise knowledge.

Pathos is a company that focuses on enhancing the drug discovery process through its AI-enabled platform. This self-learning technology leverages big data and artificial intelligence to streamline the identification and validation of drug targets, ultimately establishing their clinical efficacy. By facilitating the exploration of novel concepts, Pathos aims to support drug developers in advancing innovative therapies. The platform is designed to manage the entire end-to-end process of designing and developing new therapeutics, thereby significantly reducing the time required for medication development.

Second Front Systems, Inc. is a software development company based in Arlington, Virginia, that focuses on enhancing government access to venture capital-backed technologies for national security missions. Established in 2014, the company offers Atlas Fulcrum, a platform that helps users identify, assess, and utilize innovative commercial technologies. Additionally, Second Front provides program management and system integration services to facilitate the delivery of technology to military personnel. The High Technology Council, an enterprise consortium established by the company, brings together key industry players to leverage commercially developed technologies for government-funded national security efforts. Second Front also specializes in configuring, securing, and deploying compliant software applications for global government customers, ensuring that users have access to a fully managed production environment tailored for national security applications.

MBX Biosciences, Inc. is a biotechnology company based in Carmel, Indiana, specializing in the development of therapeutics for rare endocrine disorders. Established in 2018, the company focuses on creating peptides aimed at treating genetic diseases that affect glandular hormones, which play a crucial role in the body’s chemical messaging system. By targeting conditions with inadequate treatment options, MBX Biosciences is dedicated to discovering, developing, and commercializing innovative endocrine therapeutics.

Zenas BioPharma is a clinical-stage biopharmaceutical company based in Florida, dedicated to developing immune-based therapies for patients. The company's lead product candidate, obexelimab, is a bifunctional monoclonal antibody that targets both CD19 and FcγRIIb, which are found on B cells. This innovative approach aims to inhibit the activity of B cells involved in various autoimmune diseases while preserving their overall population, thus offering a potential therapeutic advantage over traditional treatments that deplete these cells.

Perplexity is an artificial intelligence-based search engine platform that combines large language models with traditional search engines. It leverages natural language processing and generative AI technologies to deliver conversational responses to user queries, aiming to enhance the search experience beyond standard results. The platform is designed to facilitate the development of safe and beneficial artificial general intelligence, offering an open-source environment accessible to the public. This allows clients to acquire skills and knowledge in software development, positioning Perplexity as a bridge between conventional search capabilities and advanced AI-driven assistance.

Inkitt GmbH operates an online community that connects writers and readers, facilitating the sharing and promotion of stories across various genres, including horror, romance, and sci-fi. Founded in 2013 and based in Berlin, the company publishes books using crowd wisdom and data-driven insights to predict future bestsellers. Its core platform, Inkitt, allows authors to share their works in progress and receive feedback from readers, who can access these manuscripts for free for a limited time. In addition to Inkitt, the company also operates Galatea, which sells optimized stories in a chapter-by-chapter format, and GalateaTV, which adapts successful e-books into short-form television series. Inkitt's proprietary ReadRank algorithm identifies high-potential stories, enhancing the overall user experience and driving its publishing success. The company aims to leverage AI for hyper-personalization, tailoring stories to individual reader preferences across multiple media formats.

Pair Eyewear, founded in 2017 and based in New York, specializes in customizable eyeglasses for children. The company offers a unique product line that includes base frames, which are standard glasses, and top frames, which are snap-on fronts that can be easily changed to reflect a child's evolving interests and personalities. By leveraging an e-commerce platform, Pair Eyewear aims to transform the eyeglass experience into an engaging activity for children while simplifying the process for parents. The brand focuses on quality and affordability, providing eyewear that combines style with functionality, featuring hand-polished acetate frames and shatterproof polycarbonate lenses.

Pulumi Corporation operates an infrastructure-as-a-code platform that facilitates the development, deployment, and management of cloud applications and infrastructure. Founded in 2017 and based in Seattle, Washington, Pulumi offers the Pulumi SDK, an open-source tool that enables developers and DevOps teams to utilize programming languages for defining and managing cloud services across various environments, including public, private, and hybrid clouds. The platform supports a range of application types, from serverless functions to containerized applications, and emphasizes collaboration among teams to streamline cloud engineering processes. By providing a consistent workflow for delivering and securing applications, Pulumi helps businesses effectively create modern applications and manage their cloud environments.

Spyglass Pharma specializes in developing innovative treatments for chronic ophthalmic diseases, leveraging advanced technology to enhance patient care and vision. The company focuses on creating ophthalmic devices and a drug delivery platform that addresses unmet needs in areas such as cataracts and lens replacement surgeries. Its delivery system is designed to be implanted alongside intraocular lenses during standard cataract procedures, allowing surgeons to administer multi-year therapies for chronic conditions. This approach aims to improve the accessibility and affordability of quality eye treatments for patients, ensuring better outcomes in ophthalmic care.

Instabase, Inc. is a technology company based in San Francisco, California, founded in 2015. It specializes in developing a platform that automates document processing workflows and analyzes unstructured data. The platform integrates various capabilities, including optical character recognition, data classification and extraction, and natural language processing, allowing organizations across sectors such as insurance, finance, and healthcare to streamline operations and improve decision-making. Additionally, Instabase provides a developer kit that enables the creation of customized business applications, helping institutions embed artificial intelligence into their systems and processes. Through its innovative solutions, Instabase aims to address significant business challenges and facilitate transformational outcomes for its clients.

Strive Health, LLC, founded in 2018 and based in Denver, Colorado, specializes in solutions for chronic kidney disease. The company operates dialysis centers and employs a technology-enhanced clinical model to improve patient outcomes and experiences. Strive Health works collaboratively with innovative payers and providers to transform kidney care by focusing on the entire healthcare journey of chronic kidney disease patients, from primary care engagement to dialysis treatment. The company utilizes predictive analytics and comparative data to identify at-risk patients and aims to reinvent primary care to address kidney disease proactively, reducing the need for inpatient services and promoting home dialysis options. Backed by notable investors, Strive Health is committed to enhancing the management and care of patients with chronic kidney disease.

Mojo Vision Inc. is a company based in Saratoga, California, established in 2015, that specializes in augmented reality technology. The firm is focused on developing high-performance micro-LED displays for various applications, including consumer, enterprise, and government sectors. It has created the world's smallest and densest dynamic display integrated into a smart contact lens, designed to provide users with timely information without disrupting their focus. This innovative product allows for hands-free connectivity and access to relevant information, thereby minimizing reliance on traditional mobile devices. Additionally, Mojo Vision has formed a joint development agreement with Menicon Co., Ltd. to explore smart contact lens products further, leveraging its advanced micro-LED technology and manufacturing processes to disrupt the display industry.

Outrider, Inc. is a software company that specializes in automating logistics hubs through the use of electric, self-driving trucks. Established in 2017 and based in Golden, Colorado, Outrider provides a software-as-a-service (SaaS) solution designed for customer-owned freight and transportation fleets. The company offers a comprehensive system comprised of web-based management software, autonomous driving controls for electric yard trucks, and necessary site infrastructure. Its technology automates various yard operations, including the movement of trailers and the engagement and disengagement of trailer connections, thereby eliminating hazardous and repetitive manual tasks. By focusing on the development of zero-emission systems, Outrider aims to enhance safety and efficiency for large enterprises reliant on logistics.

Escient Pharmaceuticals is a biotechnology company based in San Diego, California, that develops and manufactures drugs targeting G protein-coupled receptors (GPCRs) for the treatment of neuro-immuno-inflammatory and autoreactive diseases. Founded in 2017, the company specializes in harnessing the therapeutic potential of specific orphan GPCRs, particularly the Mas-Related G-Protein Receptors (Mrgprs), to address various neurosensory-inflammatory disorders. Escient's innovative approach aims to provide first-in-class therapies for conditions associated with mast cell-mediated disorders and cholestatic pruritus, thereby expanding treatment options for healthcare providers and patients facing these challenging diseases.

Inversago Pharma Inc. is a preclinical-stage biotechnology company based in Montreal, Canada, focused on developing innovative therapies targeting metabolic and fibrotic disorders. The company specializes in peripherally-restricted CB1 receptor inverse agonists, which aim to offer new treatment options for conditions such as Prader-Willi syndrome, diabetes, and related metabolic disorders. Inversago Pharma's research includes addressing complications associated with diabetic kidney disease, non-alcoholic steatohepatitis, and various fibrotic diseases, including interstitial lung disease. Founded in 2015, the company is dedicated to enhancing patient outcomes through its pioneering approach to CB1 blockade.

Evident is a leading provider of business credentialing solutions, operating a comprehensive platform that connects insurers and enterprises with millions of businesses globally. The company specializes in managing identity and credential verification, utilizing advanced AI to streamline the verification process while ensuring compliance with regulatory standards. Its platform is designed to identify and mitigate third-party risks across multiple domains, offering data-driven insights and a customizable framework to meet the specific needs of clients. By facilitating rigorous credentialing, Evident empowers businesses to monitor and manage risks effectively, enhancing their operational efficiency and compliance capabilities.

Moximed, Inc. is a medical technology company based in Hayward, California, focused on developing innovative solutions for patients with knee osteoarthritis. The company offers the Atlas System, an implantable joint unloader designed to alleviate pain for individuals suffering from medial compartment knee osteoarthritis. This system operates similarly to a shock absorber, providing dynamic load reduction to minimize joint pain and enhance mobility. Moximed also features the MISHA Knee System, which offers an outpatient treatment option for patients who have not found relief through other therapies and are not suitable candidates for knee replacement surgery. By addressing the specific needs of osteoarthritis patients, Moximed aims to improve their quality of life while potentially delaying the need for more invasive surgical interventions. Founded in 2006, the company serves patients and medical professionals worldwide.

Super is a social commerce platform that enables leaders to become self-made entrepreneurs and builds logistics networks. The company features Superagen, an agent-led commerce group buying that enables community leaders to become retailers within their communities.

Genies, Inc. is a company specializing in avatar technology, enabling users to create personalized digital avatars for social media and messaging applications. By offering tools for designing avatars, avatar wearable fashion, and interactive experiences, Genies allows individuals to express their thoughts and feelings in a unique digital format. The company has gained significant traction among cultural influencers and has partnered with major music labels, serving as the official avatar provider for their artists. Genies has also launched consumer offerings, including an AR Developer Kit that facilitates the creation of interoperable avatar experiences in augmented reality. Their initial product, Silver Studio, allows users to design and trade digital fashion items. Founded in 2011 and headquartered in Venice, California, Genies has successfully raised substantial investment, positioning itself as a leader in the avatar space and driving engagement for brands through the sale of exclusive digital goods.

Built Robotics Inc. is a technology company focused on automating the construction industry through the development of AI guidance systems that transform heavy equipment into autonomous robots. Founded in 2016 and headquartered in San Francisco, California, the company integrates various sensors, including GPS, cameras, and Lidar, with advanced software to enable earthmoving equipment to operate autonomously. Built Robotics aims to address the workforce gap in the construction sector, particularly in the $300 billion solar industry, by automating repetitive tasks and facilitating the construction of critical infrastructure such as wind farms, oil and gas pipelines, and new housing developments.

Timescale, Inc., established in 2011 and headquartered in New York with offices in Stockholm and Los Angeles, specializes in data analysis platforms designed for scale, ease of use, and complex queries. Its flagship product, TimescaleDB, is an open-source time-series database that supports full SQL, optimized for advanced analytics and production use cases. Timescale serves software developers and businesses worldwide, enabling them to build and analyze time-series and machine data applications.

Beyond Identity, Inc. offers a cloud-native passwordless identity management platform that enhances secure authentication by replacing traditional passwords with X.509-based certificates. Founded in 2019 and based in New York, the company provides a comprehensive suite of features including frictionless login, biometric authentication, and Single Sign-On (SSO) integration for various users such as employees, contractors, and suppliers. Its innovative approach utilizes asymmetric-key cryptography to create a robust Chain of Trust, which incorporates user and device identities along with real-time security posture assessments for adaptive risk-based authentication. This technology not only improves security by eliminating credential-stuffing attacks but also facilitates increased business agility and efficiency, allowing organizations to adopt new business models and significantly reduce operational costs while achieving complete passwordless identity management.

FTX is a cryptocurrency exchange company that specializes in developing a professional trading platform, supporting features such as quarterly and perpetual futures, leveraged tokens, and OTC trading. It aims to cater to both professional trading firms and first-time users, offering an intuitive and robust trading environment. FTX was incubated by Alameda Research, ensuring it had industry order books from its inception. Additionally, FTX Ventures, its investment arm, provides equity and/or token investments to blockchain companies at various stages, supporting founders and maintaining their decision-making flexibility.

Virtru is a data security company based in Washington, D.C., founded in 2012. It offers a data protection platform that enables organizations to secure sensitive information while ensuring ease of use. The platform supports compliance with various regulations, including HIPAA, FERPA, CJIS, and ITAR, allowing businesses to maintain control over their data throughout its lifecycle—from creation and storage to sharing and analysis. Virtru is known for its development of the Trusted Data Format (TDF), an open industry standard for persistent data protection. More than 20,000 organizations across diverse sectors rely on Virtru's privacy technologies to safeguard their data.

InCarey is a comprehensive medical service platform based in Shanghai, China, founded in 2011. The company specializes in the management of patients with chronic and vertical diseases, integrating medical, pharmaceutical, and insurance resources to deliver a one-stop solution for long-term healthcare needs. Its cloud-based platform offers professional disease management services, facilitating one-on-one interactions between doctors and patients. Additionally, InCarey's e-commerce capabilities enable users to obtain medications for major diseases efficiently. The platform is designed to address the complexities of chronic disease management, providing innovative payment solutions and a streamlined approach to healthcare services.

Forethought, established in 2017 and based in Palo Alto, California, specializes in developing AI models for question-answering and information retrieval. The company's flagship product, Agatha Answers, is a smart agent that integrates into customer support teams' workflows, providing real-time assistance, automating repetitive tasks, and offering predictive insights to enhance efficiency and productivity.

Anyscale, Inc. is a technology company based in Berkeley, California, founded by the creators of the open-source project Ray. It specializes in developing distributed programming platforms and tools that simplify the creation and scaling of artificial intelligence applications. Anyscale's software enables developers and machine learning engineers to effortlessly scale their applications from local environments to the cloud, eliminating the need for complex infrastructure. The company's framework allows users of varying skill levels to build and deploy compute-intensive applications efficiently, facilitating faster and more cost-effective market entry for AI products. Anyscale aims to enhance the end-to-end AI lifecycle, making it accessible for organizations to leverage AI technologies.

Block Renovation is a home renovation platform that integrates design, construction labor, and materials to create a seamless renovation experience for homeowners and contractors. Founded by Koda Wang and Luke Sherwin, the company aims to simplify the often complex and confusing process of home renovations. By bringing design, sourcing, and project management together, Block Renovation provides homeowners with clarity on outcomes, quality, pricing, and timelines. This approach not only enhances the experience for homeowners looking to improve their living spaces but also offers a more efficient working method for contractors.

Stride Health, Inc. operates a health benefits platform tailored for independent workers and part-time employees in the United States. The company provides a range of affordable health coverage options, including dental plans, doctor visits, and prescription insurance. By simplifying the enrollment process, Stride Health enables users to quickly select their most cost-effective health plans while also offering assistance from personal advisors to help navigate any complexities. Founded in 2013 and based in San Francisco, California, Stride Health was previously known as Covered, Inc. The company's mission is to make health insurance more accessible and manageable for those who may not have traditional employment benefits.

Clarifai, Inc. is a prominent provider of advanced artificial intelligence solutions specializing in image recognition, natural language processing, and audio recognition. Founded in 2013 by Matt Zeiler, Ph.D., the company develops a deep learning platform that enables organizations to convert unstructured data—such as images, videos, text, and audio—into structured data efficiently and accurately. Clarifai's image recognition technology is capable of detecting near-duplicates, categorizing objects, and tagging images, while also allowing users to search for similar images within extensive uncategorized collections through a combination of semantic and visual similarity. Additionally, the company offers a labeling tool called Labeler, which aids in dataset labeling, AI training, and model auto-scaling in production environments. Headquartered in New York, with an office in Tallinn, Estonia, Clarifai employs a distributed team across various countries, including the United States, Canada, Argentina, and India.

Sisu is a decision intelligence engine that allows users to efficiently and comprehensively utilize their cloud data. Companies such as Mastercard, Autodesk, Samsung, Upwork, Wayfair, Equinox, Udacity, and Gusto leverage Sisu to enhance their customer experiences, increase revenue growth, and reduce incident rates.

Pager, Inc. operates an on-demand service platform that connects patients with healthcare services in various settings, including their homes, offices, and hotels. The company offers a mobile application that addresses urgent care needs such as infections, fevers, and allergies, while also providing services like nurse chat, teleconsultations, screening, vaccinations, and prescription delivery. Pager aims to improve healthcare access and decision-making by employing a flexible platform that serves health plans and systems, enhancing consumer experience through information, guidance, and coordination. By integrating clinical and service teams with advanced technology, Pager facilitates triage, telemedicine, appointment scheduling, and health advocacy, fostering a comprehensive care experience. The company, incorporated in 2013 and based in New York, supports over 15 million covered lives in the United States and Latin America.

Allay Therapeutics is focused on developing innovative pain management solutions aimed at improving post-surgical recovery for patients. The company utilizes a proprietary technology platform that integrates validated non-opioid analgesics with biopolymers to create dissolvable therapeutic products. These products are designed to deliver targeted pain relief at the surgical site over extended periods, significantly longer than conventional pain treatments. Allay's lead investigational product, ATX101, is currently undergoing evaluation in a Phase 2 clinical trial for total knee arthroplasty surgeries. With a team of experienced entrepreneurs, scientists, and clinicians based in the San Francisco Bay Area and Singapore, Allay Therapeutics is dedicated to transforming the approach to pain management and addressing the limitations associated with opioid use.

Tulip Interfaces, Inc. specializes in creating applications for the manufacturing industry that enhance shop floor operations. Founded in 2012 and based in Somerville, Massachusetts, the company offers a no-code platform that allows organizations to integrate data from various sources, including sensors and existing equipment. This integration facilitates the creation of digital work instructions and provides real-time visibility into operations, including the performance of personnel and machinery. Tulip serves a diverse range of industries, including consumer electronics, pharmaceuticals, apparel, and medical devices, helping companies improve productivity, quality, and operational efficiency. By leveraging advanced technologies such as intelligent hardware sensors, computer vision, and machine learning, Tulip's platform enables organizations to digitally transform their operations and achieve better end-to-end traceability.

ARRIS specializes in additive molding technology for creating advanced performance composites tailored for mass-market applications such as aerospace, automotive, and consumer products. The company’s innovative manufacturing process focuses on the precise alignment of continuous carbon fibers, allowing for the integration of electronic components and multifunctional materials into a single, topologically optimized part. This technology enables clients to leverage high-performance composites, enhancing the capabilities and efficiency of their products while meeting the demands of modern manufacturing.

Aetion, Inc. is a healthcare analytics company that specializes in real-world evidence (RWE) and outcomes-based analytics solutions. Founded in 2012 and based in New York City, Aetion develops the Aetion Evidence Platform, which leverages everyday clinical and financial interactions within the healthcare system to generate critical insights about the effectiveness and value of medical treatments. This platform serves a diverse clientele, including life sciences companies, payers, providers, medical device manufacturers, and academic institutions, allowing them to analyze data from various sources such as claims, electronic health records, registries, and clinical trials. Aetion’s patented rapid-cycle analytics technology facilitates real-time collaboration among stakeholders, enabling them to make informed decisions and optimize patient care. The company has formed strategic partnerships with leading organizations, including McKesson, to enhance its offerings and expand its reach in the healthcare sector.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Arcellx is a clinical-stage biotechnology company focused on developing innovative cell therapies for patients with cancer and other incurable diseases. The company aims to enhance the safety, effectiveness, and accessibility of these therapies. Its lead product candidate, CART-ddBCMA, targets relapsed or refractory multiple myeloma and is currently undergoing a Phase 1 clinical study. This therapy has received multiple designations from the U.S. Food and Drug Administration, including Fast Track and Orphan Drug status. Additionally, Arcellx is advancing its controllable CAR-T therapy, ARC-SparX, through two clinical programs aimed at treating relapsed or refractory multiple myeloma and acute myeloid leukemia.

Cleo is a family support system that employers offer working parents, by helping families navigate their journey from fertility, to pregnancy, to parenting of newborns, infants, toddlers, and children to age 5. Employers choose Cleo as a strategic partner to power their culture transformation and see increased employee retention, more diverse and inclusive workplaces, and reduced health claims. Cleo supports parents globally in 50+ countries and works with forward-thinking companies like eBay, LinkedIn, Uber, and Straus Family Creamery and many others. Cleo is headquartered in San Francisco and is backed by Felicis Ventures, Forerunner Ventures, Greylock Partners, and NEA. Learn more at hicleo.com.

Monte Rosa Therapeutics is a biotechnology company focused on developing innovative cancer therapeutics that utilize molecular glue degraders (MGDs) to modulate protein degradation pathways. By leveraging the body's natural mechanisms for protein destruction, these small molecule drugs selectively target and degrade disease-causing proteins. The company employs its QuEEN platform, which combines artificial intelligence and proprietary experimental tools, to identify relevant proteins for degradation. With a diverse library of over 50,000 MGD molecules, Monte Rosa's lead candidate, MRT-2359, specifically targets the translation termination factor protein GSPT1, showing promise for treating MYC-driven tumors. The company aims to advance its pipeline of pioneering therapies for cancer and other diseases.

Nuvolo Technologies Corporation offers a cloud-based enterprise asset management platform designed to support the lifecycle management of assets in various sectors, including healthcare, manufacturing, and facilities management. Founded in 2013 and headquartered in Paramus, New Jersey, Nuvolo innovates on the ServiceNow platform to provide a user-friendly experience for mobile and online users. The company’s solutions encompass implementation, support, tracking, reporting, and analytics, aimed at optimizing operational efficiency and improving asset management. Nuvolo also emphasizes security, workflow automation, and accurate inventory data, making it a comprehensive choice for businesses looking to enhance their asset management capabilities. With additional offices in London, Sofia, and Pune, Nuvolo maintains a global presence through strategic partnerships with firms such as KPMG and Unisys.

Burrow, Inc. is a New York-based furniture company that designs, manufactures, and supplies a range of home furnishings, including customizable sofas, sectionals, loveseats, armchairs, and ottomans, as well as tables, rugs, and various accessories. Founded in 2016, Burrow focuses on creating luxury furniture that is both easy to move and comfortable, utilizing sustainably-sourced hardwood and non-toxic, scratch- and stain-resistant fabrics. The company aims to reinvent the home furnishing experience by offering personalized and durable products that allow customers to avoid traditional retail markups. Burrow sells its items through physical showrooms in several states, including Washington, Massachusetts, Texas, and California, as well as through its online platform. The company's manufacturing facility is located in Mexico City, Mexico.

Personal Genome Diagnostics, Inc. specializes in patient-specific cancer genome analysis using advanced digital characterization and monitoring technologies. Founded in 2010 and based in Baltimore, Maryland, the company offers a range of products and services aimed at improving cancer diagnosis and treatment. Their METDetect Assay detects MET gene amplifications in cancer patients' circulation, providing detailed reports on tumor-specific alterations. The LungSelect product identifies actionable genetic changes in plasma from non-small cell lung cancer patients, while PGDx elio plasma resolve is a diagnostic test that detects various genetic alterations in circulating cell-free DNA. Additionally, the company offers RNAcomplete, which allows for the extraction of total RNA and genomic DNA from single tissue samples, and CancerXOME, which analyzes the coding regions of numerous genes. Personal Genome Diagnostics collaborates with institutions like Mayo Clinic and has partnerships with KingMed Diagnostics to further enhance cancer genome research and diagnostics.

Sitetracker is a software-as-a-service (SaaS) platform that specializes in the deployment, operation, and servicing of critical infrastructure and technology. It provides a comprehensive project management solution tailored for high-volume, repeatable, and distributed projects across industries such as telecommunications, alternative energy, and utilities. The Sitetracker platform utilizes features like artificial intelligence, automation, and actionable analytics to optimize the entire asset lifecycle. By conducting capacity planning and leveraging vendor analytics, it helps organizations identify staffing needs and resource bottlenecks, enabling stakeholders to effectively plan, deploy, maintain, and grow their capital asset portfolios. Industry leaders, including major companies in telecommunications and utilities, depend on Sitetracker to manage millions of sites and projects, collectively representing significant portfolio holdings worldwide.

KONUX GmbH, founded in 2014 and based in Munich, Germany, specializes in the development of Industrial Internet of Things (IIoT) solutions that integrate smart sensor systems with artificial intelligence-based analytics. The company's offerings include switch monitoring, asset monitoring, rolling stock monitoring, anomaly detection, and predictive analytics, all aimed at enhancing railway and industrial operations. By providing real-time monitoring and predictive maintenance capabilities, KONUX helps clients improve the reliability, capacity, and cost-efficiency of their railway systems. The company has expanded its reach across multiple countries in Europe and Asia and has been recognized by the World Economic Forum as one of the world's most innovative start-ups. With over $130 million raised from leading investors, KONUX is committed to modernizing railroad operations and contributing to a sustainable future in mobility.

Bestow Inc., established in 2016 and based in Dallas, Texas, operates as a digital life insurance company. It provides life insurance services to individuals, leveraging data-driven technology applications and algorithmic underwriting to assess risks efficiently. The company partners with top carriers to enhance processes from origination to administration, aiming to increase financial stability for all.

Founded in 2014 by Marcela Sapone and Jessica Beck, Alfred is the largest and most advanced residential management platform. Since its inception, Alfred has focused on providing a resident-first experience. With an unparalleled knowledge of what residents want and technology that boosts income and efficiency for owners and operators, Alfred provides a single stop that elevates the rental ecosystem for all involved. Named by Fast Company as one of the Top 50 Most Innovative Companies, Alfred’s AOS technology drives lower operating costs and higher returns for property owners and operators. Through strategic partnerships with international real-estate owners and operators such as Hines, Related, RXR, Greystar, Invesco, Brookfield and J.P. Morgan, With RKW, Alfred’s portfolio now extends to more than 300,000 residents in 44 cities across the U.S. and Canada and has planned expansions in Europe, Israel and Asia.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Everactive, Inc., also known as Everactive Insights, Inc., specializes in the development of wireless sensing devices and technologies tailored for Industrial Internet of Things (IoT) applications. The company produces ultra-low-power chips that enable battery-less wireless sensors, facilitating data generation and analytics for various industrial operations. Its innovations include PsiKick integrated circuits, which support programmable processing, power management, and RF communication. Everactive's solutions encompass steam trap monitoring, flare system monitoring, and machine health monitoring, allowing for continuous analysis of industrial assets. Founded in 2012 and headquartered in Santa Clara, California, Everactive also has locations in Charlottesville, Virginia, and Ann Arbor, Michigan. The company’s technology is based on energy harvesting, enabling low-cost and long-lived instrumentation that supports sustainable and scalable IoT applications.

Amplyx Pharmaceuticals is a small molecule drug development company focused on creating innovative therapies for life-threatening infections, particularly in patients with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in developing oral and injectable anti-infective drugs, including antifungal agents aimed at treating invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by combining them with additional small molecules. This strategy addresses critical treatment needs in hospital settings and provides effective therapy options for patients after discharge, particularly those undergoing chemotherapy and other immunosuppressive treatments.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

ChromaCode, Inc. is a molecular diagnostics company based in Carlsbad, California, founded in 2012. The company specializes in developing innovative testing solutions for infectious diseases, cancer, and non-invasive prenatal testing (NIPT) by utilizing patented mathematical methods and algorithmic enhancements. ChromaCode's products significantly enhance the multiplexing capabilities of quantitative polymerase chain reaction (qPCR) instruments, allowing laboratories to perform cost-effective testing of multiple targets from a single sample. Their offerings include software, reagents, and assays that improve signal processing and overall assay performance, making diagnostics more accessible and efficient. Among their notable products is the HDPCR Tick-Borne Pathogen Panel, a multiplex test that detects various tick-borne pathogens in one assay.

Black Diamond Therapeutics, Inc., established in 2014 and headquartered in Cambridge, Massachusetts, specializes in precision oncology medicine. The company discovers and develops small molecule therapies that are tumor-agnostic, meaning they target specific genetic mutations across various cancer types rather than being limited to a single cancer indication. Its lead product candidate, BDTX-189, inhibits non-canonical and oncogenic mutations of ErbB kinases epidermal growth factor receptor (EGFR). The company's Mutation-Allostery-Pharmacology platform enables it to target undrugged mutations in patients with genetically defined cancers, offering new treatment options where few exist. Black Diamond Therapeutics is also advancing early-stage pipeline programs targeting allosteric mutations in other cancer-related kinases.

Sentry is an open-source platform focused on improving workflow productivity by monitoring application performance and error reporting. The company provides a tool that captures real-time data on errors and crashes within software applications, allowing users to prioritize and identify issues as they occur. This tool offers detailed insights into deployments and assists in reproducing and fixing crashes, enabling organizations to understand which errors are most detrimental to their operations. By highlighting the impact of these issues on business performance, Sentry helps its clients enhance their software reliability and ultimately improve their bottom line.

PlayVS is an operator of an eSports platform designed to facilitate organized competitions for high schools. The company provides a platform that enables the organization of online tournaments, allowing students to compete against one another for cash prizes and titles. By fostering eSports programs in high schools, PlayVS helps teen gamers form teams and engage in competitive play, connecting them with players from other schools and creating opportunities to participate in state championships. This initiative aims to enhance the overall experience of high school eSports, ensuring that both players and schools can stay informed and involved in the rapidly evolving world of competitive gaming.

Echodyne, established in 2014 and based in Kirkland, Washington, specializes in developing and marketing metamaterials-based radar systems. The company offers a range of radar solutions, including 3D Security radar for all-weather, compact, and solid-state sensor performance; Metamaterial Electronically Scanning Array (MESA) technology for high-performance phased-array radar at breakthrough cost levels; and Echoguard for ground-based airspace management. Additionally, Echodyne provides Acuity Software for customization and data processing, along with various deployment kits and accessories. Their products cater to commercial markets, government, defense, and industry, enabling autonomous applications in drones, vehicles, and heavy machinery, even in complex and challenging environments.

Heap Inc. is a company that develops an analytics infrastructure designed for online businesses, enabling them to capture and analyze customer interactions across web, mobile, and cloud platforms. Founded in 2012 and headquartered in San Francisco, California, Heap's solution automates the collection and organization of customer behavioral data, such as clicks, transactions, and form submissions, without requiring additional coding. This streamlined approach allows businesses to gain a comprehensive understanding of their users, facilitating informed decision-making and enhancing product development. Heap serves a diverse range of industries, including e-commerce, financial services, and SaaS, with over 6,000 clients that include notable companies across various sectors. The company is committed to empowering organizations to focus on insights and actions that drive business success.

Expel, Inc. is a managed security operations provider based in Herndon, Virginia, specializing in managed detection and response (MDR) services. Founded in 2016, the company offers a comprehensive security operations center (SOC)-as-a-service that monitors and responds to threats across cloud, hybrid, and on-premises environments. Expel's platform combines advanced technology with human expertise to quickly detect, analyze, and remediate security issues, including phishing, ransomware, and supply chain attacks. The Expel Workbench™ platform enhances collaboration by allowing customers to engage with live investigations and receive continuous updates, ensuring transparency throughout the security process. By filtering out false positives, Expel enables security teams to focus on strategic priorities rather than being overwhelmed by alerts, ultimately improving their overall security posture.

Tamara Mellon, established in 2011, is a luxury women's fashion brand headquartered in New York City. It designs, manufactures, and retails a range of products including shoes, bags, and ready-to-wear apparel. The company's shoe collection comprises sandals, boots, pumps, flats, and legging boots, while its apparel line features dresses, jumpsuits, tops, pants, skirts, jackets, and outerwear. Tamara Mellon sells these products through both retail and online stores in the United States and internationally, accompanied by a complimentary cobbler service for footwear purchases.

Expanse, Inc. is an enterprise software company based in San Francisco, California, that specializes in data marshalling services and IT operations management. Founded in 2012 and originally known as Qadium, Inc., the company provides organizations with an updated view of their internet-connected assets, enabling IT and security teams to monitor their global attack surface. Expanse's platform indexes global IP addresses, DNS protocol information, and other registration records, allowing organizations to discover unknown assets and manage their exposure to online threats. Trusted by major enterprises and government agencies, Expanse's technology enhances awareness and visibility, significantly reducing the risks associated with internet-connected assets and improving overall cybersecurity posture.

Igneous Systems, Inc., founded in October 2013 and headquartered in Seattle, Washington, specializes in enterprise data center infrastructure and unstructured data management. The company offers a comprehensive as-a-Service solution that provides businesses with visibility, protection, and mobility for their unstructured data on a large scale. Igneous’s cloud-native, API-enabled platform integrates various unstructured data management functions, allowing organizations to maximize the value of their data while minimizing risks and optimizing IT resource utilization. Its services include consolidated backup, file system archiving, and efficient management of unstructured data, all aimed at enhancing workflow productivity for data-centric enterprises.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, dedicated to developing and commercializing nalbuphine ER, an oral extended-release formulation. The company is focused on treating serious neurologically mediated conditions, specifically chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis, and levodopa-induced dyskinesia in individuals with Parkinson's disease. Trevi is currently conducting a Phase 2b/3 clinical trial, known as the PRISM trial, for nalbuphine ER, targeting severe pruritus associated with prurigo nodularis. The conditions being addressed share similar underlying mechanisms that involve opioid receptors in both the central and peripheral nervous systems. Founded in 2011, Trevi Therapeutics aims to provide innovative treatment options for patients suffering from these challenging health issues.

The Wing is a network of work and community spaces specifically designed for women, with locations in New York, California, and Washington, D.C. Its mission focuses on the professional, civic, social, and economic advancement of women by fostering a supportive community. The Wing's facilities feature open-plan workspaces, meeting rooms, phone booths, and an extensive all-female library. By providing these resources, The Wing enables female founders and busy professional women to find support, gain inspiration, and build their businesses in an empowering environment.

Annexon Biosciences is a clinical-stage biopharmaceutical company focused on developing innovative therapies for patients suffering from classical complement-mediated disorders affecting the body, brain, and eye. The company's research is centered around its platform technology that targets classical complement-mediated autoimmune and neurodegenerative diseases associated with the abnormal activation of C1q, a key molecule in the classical complement pathway. Annexon's lead product candidate, ANX005, is a full-length monoclonal antibody intended for intravenous use in treating autoimmune and neurodegenerative disorders. Another candidate, ANX007, is a monoclonal antibody Fab formulated for intravitreal administration aimed at neurodegenerative ophthalmic conditions. The company employs a disciplined, biomarker-driven development strategy to ensure its therapies effectively engage the target at tolerable doses within the intended patient tissues, while also exploring additional indications within both orphan and larger market segments.

Plaid Inc. is a technology company that facilitates the connection between consumers' bank accounts and applications, aiming to democratize financial services through advanced technological solutions. Founded in 2012 and headquartered in San Francisco, it provides a comprehensive suite of APIs that enable developers to create financial products connecting users with traditional financial institutions. Plaid's offerings include tools for accessing transaction history and balance data, authenticating bank accounts for payments, verifying identities, and confirming real-time account balances and income. These products support various applications in personal finances, consumer payments, lending, banking, and business finance. With a focus on enhancing both consumer experiences and developer capabilities, Plaid serves a diverse range of clients, including Fortune 50 companies, positioning itself as a vital infrastructure provider in the digital financial landscape.

NeueHealth Inc is a healthcare company dedicated to providing high-quality, coordinated care to all health consumers, particularly those in aging and underserved populations. The company focuses on making healthcare accessible and affordable through strategic partnerships with providers and payors, aligning their interests to enhance the overall healthcare experience. By leveraging technology and data analytics, NeueHealth offers a suite of services that empower independent providers and medical groups to succeed in performance-based arrangements. This approach not only optimizes clinical outcomes but also aims to drive down costs and reduce systemic waste, ultimately delivering a more personalized and efficient healthcare experience for its members across various insurance markets, including the ACA Marketplace, Medicare, and Medicaid.

Infoworks.io, Inc. is an enterprise software company that specializes in automated data management solutions for organizations managing large-scale data environments. Founded in 2014 and headquartered in Palo Alto, California, with an additional office in Bengaluru, India, the company offers DataFoundry, a tool designed to streamline data operations and orchestration. This platform facilitates the discovery, loading, organization, and management of data on Hadoop, enabling enterprises to consolidate their data and manage workflows efficiently from ingestion to analytics. Infoworks' solutions encompass various aspects of data management, including ingestion, synchronization, preparation, and orchestration, which significantly accelerate cloud migration and modernize data operations. By automating these processes, Infoworks enables organizations to unlock the value of their data while improving delivery speed for AI, machine learning, and analytics applications.

HEAVY.AI develops a big data analytics and visualization platform that helps businesses and government entities uncover valuable opportunities and risks within extensive location and time data. Its technology leverages the capabilities of modern GPU and CPU hardware to facilitate high-speed analytics and visualization. The platform features a structured query language-compliant database and an advanced visual analytics engine, allowing users to analyze and visualize large datasets efficiently. Clients from various sectors, including government, telecommunications, energy, utilities, and higher education, utilize HEAVY.AI's solutions to enhance decision-making processes and gain insights from multi-billion record datasets.

Galera Therapeutics, Inc. is a clinical-stage biopharmaceutical company headquartered in Malvern, Pennsylvania, dedicated to developing innovative therapeutics aimed at enhancing the effectiveness of radiotherapy for cancer patients. The company's lead product candidate, avasopasem manganese (GC4419), is a small molecule dismutase mimetic currently undergoing Phase III clinical trials for the treatment of radiation-induced severe oral mucositis in patients with head and neck cancer. Additionally, GC4419 is being evaluated in Phase IIa trials for the treatment of radiotherapy-induced esophagitis in lung cancer patients. Galera is also advancing another candidate, GC4711, which is in Phase I/II trials for pancreatic and lung cancers. The company's research is focused on targeting oxygen metabolic pathways to improve patient outcomes in radiation therapy, and GC4419 has received Fast Track and Breakthrough Therapy designations from the U.S. Food and Drug Administration.

Enigma Technologies, Inc. is an operational data management and intelligence company based in New York. It specializes in providing a searchable database of public records, information, and documents, facilitating streamlined operations and informed decision-making for its users. The company offers a suite of products, including Enigma Data Infrastructure, which features tools for data operations and metadata enhancement, and Enigma Solutions, tailored for specific industries such as financial services, pharmacovigilance, and insurance. Enigma also provides analysis-ready public data relevant to sectors like oil and gas, healthcare, and company reference data. Additionally, Enigma operates Enigma Labs, which focuses on developing open data tools for public use, and offers an API to support developers in creating data-rich applications. The company is recognized for its contributions to small business intelligence, delivering timely and accurate insights on the identity and risk profile of small businesses, thus aiding firms in areas such as insurance risk assessment and fraud prevention. Enigma Technologies was incorporated in 2011.

StreamSets, Inc. is a company that specializes in cloud-based DataOps solutions for modern data integration, enabling enterprises to efficiently manage the flow of big, streaming, and traditional data. Founded in 2014 and headquartered in San Francisco, California, StreamSets provides a range of tools including StreamSets Control Hub for designing and monitoring data pipelines, StreamSets Data Collector for executing data pipelines without manual coding, and StreamSets Transformer for building data transformations across various sources. The platform is designed to enhance operational excellence in managing data in motion, ensuring timely and high-quality data delivery for critical business analysis and decision-making. StreamSets serves a diverse clientele, including enterprises in the United States and internationally, and supports use cases such as data lake and warehouse integration, cloud data storage adoption, and real-time application development. The company also has offices in locations including Sunnyvale, Austin, London, Barcelona, Bengaluru, and Sydney.

MORE Health, Inc. operates a cloud-based physician collaboration platform aimed at connecting patients' attending doctors with specialists to collaboratively develop accurate diagnoses and optimal treatment plans. The platform encompasses a comprehensive clinical database, including medical history, hospital records, lab results, and medical imaging, as well as discussion tools that facilitate HIPAA-compliant video conferencing. In addition to these features, MORE Health offers a patient portal for personal health records, an Overseas Co-Diagnosis service for international patients, and a Secure Medical Record service for traveling employees. Initially launched as a concierge service for private clients, the company now provides its services as a supplemental health benefit for U.S. companies, allowing employees to access high-quality medical consultations, including co-diagnoses and independent second opinions. Founded in 2013 and based in Foster City, California, MORE Health has established strategic alliances with notable medical institutions, aiming to serve patients globally and provide access to top medical expertise during critical health decision-making.

Brandless, Inc. is an online consumer commerce platform based in San Francisco, California, that offers a diverse range of products across several categories. Founded in 2015, the company sells food items such as snacks, granola, and baby food, as well as home essentials including cleaning supplies, tableware, and office products. Additionally, Brandless provides beauty and personal care items, health and wellness products like vitamins and supplements, baby products, and pet supplies. The company aims to create a marketplace that empowers consumers to make healthier and more sustainable choices for themselves, their families, and the environment by prioritizing quality and collaboration.

Tuya is a global "AI+IoT" developer platform, and the world's leading voice AI interactive platform, connecting consumers, manufacturing brands, OEMs and retail chains, providing customers with a one-stop artificial intelligence Internet of Things solution, and covering hardware access, cloud services and App development, forming a closed loop of AI + manufacturing, providing technology and business model upgrade services for business with consumer IoT smart devices, in order to meet consumers' higher demands for hardware products. As of the end of October 2018, Tuya Smart has served 93,000 customers worldwide, connecting more than 100 million smart products in the market, creating a completely neutral "AI+IoT" model for empowering products, with total product listings of more than 30,000, selling to nearly 200 countries and regions. On the global IoT cloud platform with a distributed architecture, the daily processing device requests have reached nearly 50 billion times, daily voice AI interaction has exceeded 20 million times, and the accumulated data volume has reached 15 petabytes.

Framebridge, Inc. specializes in custom framing solutions for art and photographs, offering a streamlined online service that prioritizes customer experience. Founded in 2014 and based in Washington, D.C., the company allows users to select from a curated range of contemporary frame styles, upload images, or send physical items for personalized framing. The expert team at Framebridge handcrafts frames to meet each customer's specifications, ensuring high-quality results. Finished products are shipped directly to consumers, typically arriving within days and ready to hang. Pricing is transparent and based on the size of the framed item, starting at $39 and including free shipping. Framebridge operates manufacturing facilities in Richmond, Kentucky, and Lanham, Maryland, and has attracted investments from notable firms and individuals in the retail and technology sectors.

Nginx, established in 2011, is a technology company that specializes in developing and maintaining the open-source web server NGINX. Its offerings include application delivery, load balancing, security, and API management solutions. Key products are NGINX Plus, a software load balancer and web server; NGINX Controller, for managing NGINX Plus; NGINX Unit, a dynamic application server; NGINX Web Application Firewall; and NGINX Amplify, a SaaS monitoring tool. Headquartered in San Francisco, with offices in Cork and Singapore, Nginx operates as a subsidiary of F5 Networks.

Metacrine, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, dedicated to developing innovative therapies for liver and gastrointestinal diseases. The company is advancing its lead programs, which target the farnesoid X receptor (FXR), a key drug target in these conditions. Currently, MET409 is undergoing a Phase Ib proof-of-concept clinical trial for patients with non-alcoholic steatohepatitis, while MET642 is in a Phase 1 clinical trial for the same patient population. In addition to its FXR-focused programs, Metacrine is exploring a pipeline of novel drug candidates through its internal research and development capabilities. The company also collaborates with Novo Nordisk A/S to further research related to fibroblast growth factor 1. Metacrine was founded in 2014 and is committed to addressing unmet medical needs in liver and gastrointestinal health.

XSKY Data Technology, based in Beijing, specializes in software-defined infrastructure products and services. It offers a range of storage solutions, including XCBS (cloud), XEBS (block), XEUS (unified), XEOS (object), and XEDP (unified data platform), catering to diverse sectors such as finance, enterprise, telecom, energy, and government. XSKY is a significant contributor to the open-source Ceph storage system, ranking top 3 globally. It partners with leading tech companies like Intel and Samsung, providing scalable, cost-effective storage solutions tailored for enterprise data center innovation.

Intact Vascular, Inc. is a medical device company based in Wayne, Pennsylvania, focused on developing minimally invasive products for peripheral vascular procedures. Established in 2011, the company is known for its Tack Endovascular System, which enhances the results of peripheral balloon angioplasty in treating peripheral arterial disease (PAD) and critical limb ischemia (CLI). This innovative technology aims to improve clinical outcomes and quality of life for patients suffering from vascular diseases, offering physicians a new and effective treatment option. Intact Vascular is dedicated to creating safe, efficacious, and user-friendly medical devices for healthcare providers and their patients.

Goop Inc. is a lifestyle brand that operates an online platform offering wellness advice, curated shopping, and lifestyle content. Founded in 2008 by Gwyneth Paltrow, Goop began as a newsletter sharing travel recommendations, health-focused recipes, and shopping finds, which has since evolved into a comprehensive lifestyle site. The platform features a selection of products including apparel, beauty items, skincare, and home goods, all sourced with an emphasis on quality and wellness. In addition to retail, Goop provides a wealth of digital content, such as beauty and makeup tips, cooking recipes, and wellness advice, along with travel information and design inspiration. By connecting its audience with expert insights and curated product offerings, Goop positions itself as a trusted resource for lifestyle enhancement.

DataVisor Inc. is a company specializing in fraud and financial crime detection solutions, established in 2013 and located in Mountain View, California. The firm employs advanced unsupervised machine learning technology to predict and identify attack vectors, effectively protecting large consumer-facing organizations from various digital threats. Its key products include dCube, which enables proactive fraud detection and prevention, and dVector, which enhances fraud management through accurate signal analysis. Additionally, dEdge collects real-time intelligence from connected devices to safeguard mobile and web applications against sophisticated attacks. DataVisor addresses a wide range of fraud types, including account takeovers, fake account creations, money laundering, and promotional abuse, serving industries such as financial services, retail, e-commerce, social platforms, and telecommunications. The company's innovative approach enables organizations to respond to rapidly evolving fraud tactics and mitigate risks in real time.

Fire1, based in Dublin, Ireland, is dedicated to developing innovative therapeutic devices aimed at enhancing the lives of heart failure patients. The company has created a remote monitoring system that allows healthcare providers to access real-time patient data and insights. This technology facilitates the early detection of complications associated with heart failure, enabling proactive interventions that can lead to improved patient outcomes. Through its focus on remote monitoring, Fire1 seeks to address critical challenges in heart failure management and contribute to better healthcare solutions.

Metavention, Inc., incorporated in 2012 and based in Dover, Delaware, focuses on innovative treatments aimed at addressing metabolic diseases linked to overactive sympathetic nerves. The company has developed a renal denervation procedure utilizing its IRF denervation system, which applies radio frequency energy to specifically target these nerves. This approach is designed to provide a permanent solution for conditions such as high blood pressure and complications associated with Type 2 diabetes, including elevated glucose levels and abnormal liver function. By employing trans-catheter devices that leverage standard interventional vascular techniques, Metavention equips medical practitioners with effective tools for diagnosing and treating patients suffering from these metabolic disorders.

ThreatQuotient, Inc. is a cybersecurity company that specializes in developing a threat intelligence platform designed to help organizations effectively manage and respond to cyber threats. Founded in 2013 and headquartered in Reston, Virginia, the company offers its flagship product, ThreatQ, which integrates and correlates various external threat sources with internal security solutions to provide contextualized intelligence. This platform streamlines security operations by reducing noise, prioritizing threats, and facilitating collaboration among teams. It features capabilities such as Indicator Nurturing, which tailors indicators of compromise to specific infrastructures, as well as integrations with existing security tools and processes. ThreatQuotient's solutions support a range of use cases, including incident response and threat hunting, ultimately enhancing the efficiency and effectiveness of security operations. The company has received multiple awards for its product excellence and industry leadership, reflecting its commitment to advancing cybersecurity practices. Additionally, ThreatQuotient operates internationally, with a presence in Germany and Australia.

Eargo, Inc. is a consumer-focused medical device company based in San Jose, California, specializing in the design and development of hearing aids for individuals with hearing loss. Founded in 2010, Eargo offers a range of rechargeable hearing aids that can be controlled via smartphone, along with online hearing screenings and virtual support services to eliminate the need for in-person visits. The company's innovative approach aims to address common barriers to hearing aid adoption, such as social stigma, accessibility, and cost, thereby enhancing the quality of life for its users. Eargo sells its products directly to consumers through online platforms, positioning itself as a modern alternative to traditional hearing aid solutions.

Wheels Up is a membership-based private aviation company that specializes in on-demand flight services in the United States. By leveraging data and technology, it connects consumers with safety-vetted private aircraft, offering both programmatic and charter options. The company aims to reduce the upfront costs associated with private flying while providing flexibility, service, and safety to its members. Through its mobile app, users can easily book flights, manage accounts, and access ride-share opportunities. Additionally, members participate in the Wheels Down program, which enhances their travel experiences. Wheels Up operates a diverse fleet, utilizing owned, leased, and chartered aircraft to provide a wide range of global travel alternatives.

Tempus, established in 2015 and based in Chicago, Illinois, is a technology company specializing in precision medicine. It develops a comprehensive library of molecular and clinical data, along with an operating system that makes this information accessible and useful for patients, physicians, and researchers. Tempus offers services such as genomic sequencing, clinical data restructuring, and biological modeling, enabling real-time data-driven decisions for personalized patient care and facilitating the discovery of optimized therapeutic options.

Raise is a digital payment platform that allows consumers to purchase discounted gift cards and earn savings on transactions across various retailers. The platform allows users to buy and sell gift cards, facilitating a marketplace where individuals can exchange unwanted gift cards for cash or other cards. Raise also offers a rewards program that enables customers to earn points on purchases, which can be redeemed for future savings. By partnering with numerous brands, Raise enhances consumer choice and accessibility to various products and services while promoting cost-effective shopping solutions.

Amplyx Pharmaceuticals is a small molecule drug development company focused on creating innovative therapies for life-threatening infections, particularly in patients with compromised immune systems. Founded in 2006 and based in San Diego, California, the company specializes in developing oral and injectable anti-infective drugs, including antifungal agents aimed at treating invasive fungal infections caused by pathogens such as Candida and Aspergillus. Amplyx employs a unique platform approach that enhances the efficacy and reduces the toxicity of existing drugs by combining them with additional small molecules. This strategy addresses critical treatment needs in hospital settings and provides effective therapy options for patients after discharge, particularly those undergoing chemotherapy and other immunosuppressive treatments.

DataRobot, Inc. is a Boston-based company that specializes in developing an automated machine learning platform aimed at empowering enterprises to construct predictive models efficiently. Its offerings include DataRobot Cloud, a cloud-based platform for predictive analytics, and DataRobot MLOps, which facilitates the deployment, monitoring, and management of machine learning models across organizations. Additionally, DataRobot Enterprise provides features tailored for large organizations, such as flexible deployment options, governance, and comprehensive support. The company's solutions cater to a diverse clientele, including business analysts, data scientists, executives, and IT professionals across various sectors such as banking, healthcare, and manufacturing. Founded in 2012, DataRobot has expanded its operations internationally, with locations in London, Paris, Kyiv, Tokyo, and Singapore, and maintains a strategic partnership with Snowflake to enhance its offerings.

Complexa, Inc. is a biopharmaceutical company based in Berwyn, Pennsylvania, focused on developing treatments for severe and life-threatening diseases related to fibrosis and inflammation. Established in 2008, the company is advancing its lead compound, CXA-10, an oral nitrated fatty acid aimed at treating focal segmental glomerulosclerosis (FSGS) and pulmonary arterial hypertension (PAH). Complexa utilizes proprietary technologies that involve the synthesis of endogenous nitro-fatty acids, which serve as cell-signaling agents regulating key inflammatory pathways. This approach aims to enhance the body's natural mechanisms for resolving and repairing acute and chronic tissue injuries, with a focus on addressing various inflammatory, fibrotic, and central nervous system diseases.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, dedicated to developing and commercializing nalbuphine ER, an oral extended-release formulation. The company is focused on treating serious neurologically mediated conditions, specifically chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis, and levodopa-induced dyskinesia in individuals with Parkinson's disease. Trevi is currently conducting a Phase 2b/3 clinical trial, known as the PRISM trial, for nalbuphine ER, targeting severe pruritus associated with prurigo nodularis. The conditions being addressed share similar underlying mechanisms that involve opioid receptors in both the central and peripheral nervous systems. Founded in 2011, Trevi Therapeutics aims to provide innovative treatment options for patients suffering from these challenging health issues.

Segment provides the customer data infrastructure that helps businesses put their customers first. Using Segment, companies can collect, unify, and connect their first-party to over 200 marketing, analytics, and data warehouse tools. It was founded in 2011 and headquartered in San Francisco, California.

Transfix, Inc. is a trucking brokerage firm based in New York that specializes in connecting shippers with carriers for freight transportation across the United States. Founded in 2010, the company has developed an online freight management platform that utilizes advanced algorithms and business intelligence to enhance supply chain visibility and efficiency. Transfix offers services such as real-time shipment tracking, carrier performance insights, and support tailored to various industries, including retail, food, beverage, and manufacturing. By leveraging its Intelligent Freight Platform, Transfix aims to optimize logistics processes, reduce empty miles, and improve overall supply chain performance for its clients.

Nightstar Therapeutics plc is a clinical-stage gene therapy company based in London, focused on developing innovative one-time treatments for rare inherited retinal diseases. The company’s lead product candidate, NSR-REP1, is currently in phase 3 clinical development for choroideremia, while NSR-RPGR is undergoing phase 2/3 trials for X-linked retinitis pigmentosa. Additionally, Nightstar is developing NSR-BEST1 and NSR-ABCA4, with the latter in preclinical development for Stargardt disease. Founded in 2017, Nightstar Therapeutics aims to address the unmet medical needs of patients suffering from these conditions.