Prolog Ventures

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

CleanSlate UV develops sanitization devices aimed at disinfecting smartphones and other portable electronics. The company's technology allows staff, patients, and visitors to effectively sanitize their personal items while also promoting hand hygiene, thereby reducing the risk of hospital-acquired infections. By harnessing the power of UV light, CleanSlate UV's products are designed to eliminate harmful pathogens without damaging sensitive touch screens. The devices not only ensure effective disinfection but also collect data for sanitization compliance, addressing the increasing challenge of device hygiene in various environments.

CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

Kinnos Inc. is a biotechnology company based in Brooklyn, New York, that specializes in improving disinfection practices through innovative color technology. Founded in 2014, the company manufactures a powdered additive called Highlight, which enhances the visibility of disinfectants, ensuring thorough cleaning and compliance during disinfection processes. Highlight provides real-time color-change feedback, allowing users to see where disinfectants have been applied, which helps prevent disease outbreaks on various surfaces. In addition to Highlight, Kinnos also offers Highlight Wipes, a dispensing machine for wipes, and Highlight Powder, another form of their disinfectant additive. The company's mission is to empower individuals to disinfect with confidence and to enhance public health through effective and visible disinfection.

Kinnos Inc. is a biotechnology company based in Brooklyn, New York, that specializes in improving disinfection practices through innovative color technology. Founded in 2014, the company manufactures a powdered additive called Highlight, which enhances the visibility of disinfectants, ensuring thorough cleaning and compliance during disinfection processes. Highlight provides real-time color-change feedback, allowing users to see where disinfectants have been applied, which helps prevent disease outbreaks on various surfaces. In addition to Highlight, Kinnos also offers Highlight Wipes, a dispensing machine for wipes, and Highlight Powder, another form of their disinfectant additive. The company's mission is to empower individuals to disinfect with confidence and to enhance public health through effective and visible disinfection.

BioClarity is an online marketplace focused on addressing the skincare needs of young adults, particularly in the realm of acne treatment. The company offers a variety of botanical and plant-based skincare products that are clinically tested to effectively reduce redness and pore size. By combining natural ingredients with scientific research, BioClarity aims to provide customers with chemical-free beauty solutions that promote healthy, glowing skin at an affordable price. This approach reflects a commitment to meeting the demands of a market increasingly seeking effective and environmentally friendly skincare options.

SchoolCare is a digital health platform dedicated to enhancing pediatric healthcare in K-12 public schools. By providing free health technology, it assists school nurses in delivering effective care and ensuring student safety. The platform captures essential health information, including student medical charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. This connectivity allows for timely alerts about health events and supports the efficient operation of public school health programs. By addressing gaps in traditional care coordination, SchoolCare aims to improve health outcomes for children, ensuring that they receive consistent and comprehensive care throughout their school experience.

CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

TOMA Biosciences, Inc. is a genomics company based in Foster City, California, focused on developing reagent kits and cancer testing technologies that assist laboratories and researchers in identifying genomic changes in tumors. The company offers TOMA OS-Seq, an oncology-focused gene analysis solution that leverages advanced next-generation sequencing technology to detect clinically significant alterations in tumor DNA. This information is crucial for physicians to optimize treatment strategies for cancer patients by providing insights into the genomic errors present in their tumors. TOMA Biosciences serves a wide range of clients, including laboratories, hospital systems, and research institutions globally, and aims to improve clinical outcomes through its innovative testing solutions. The company has been operational since its incorporation in 2011.

Spindrift Beverage Co., Inc., founded in 2010 and based in Newton, Massachusetts, specializes in producing unsweetened sparkling beverages made with real squeezed fruit. The company offers a range of drinks that combine triple-filtered sparkling water with authentic fruit flavors, such as lemon, raspberry lime, and strawberry, without any artificial sweeteners. Spindrift aims to provide consumers with refreshing beverages that promote a healthy and active lifestyle through the use of real ingredients.

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

Spindrift Beverage Co., Inc., founded in 2010 and based in Newton, Massachusetts, specializes in producing unsweetened sparkling beverages made with real squeezed fruit. The company offers a range of drinks that combine triple-filtered sparkling water with authentic fruit flavors, such as lemon, raspberry lime, and strawberry, without any artificial sweeteners. Spindrift aims to provide consumers with refreshing beverages that promote a healthy and active lifestyle through the use of real ingredients.

CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

SchoolCare is a digital health platform dedicated to enhancing pediatric healthcare in K-12 public schools. By providing free health technology, it assists school nurses in delivering effective care and ensuring student safety. The platform captures essential health information, including student medical charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. This connectivity allows for timely alerts about health events and supports the efficient operation of public school health programs. By addressing gaps in traditional care coordination, SchoolCare aims to improve health outcomes for children, ensuring that they receive consistent and comprehensive care throughout their school experience.

SchoolCare is a digital health platform dedicated to enhancing pediatric healthcare in K-12 public schools. By providing free health technology, it assists school nurses in delivering effective care and ensuring student safety. The platform captures essential health information, including student medical charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. This connectivity allows for timely alerts about health events and supports the efficient operation of public school health programs. By addressing gaps in traditional care coordination, SchoolCare aims to improve health outcomes for children, ensuring that they receive consistent and comprehensive care throughout their school experience.

IntelliCyt Corporation specializes in the development of high-throughput cell- and bead-based screening solutions tailored for the life sciences sector, particularly in drug discovery, antibody development, and immunology. Founded in 2006 and based in Albuquerque, New Mexico, the company offers a comprehensive iQue Screener platform that integrates instrumentation, software, and reagents to facilitate high-content multiplex analysis of samples in liquid suspension. This platform is complemented by ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. IntelliCyt’s innovative technologies significantly enhance the efficiency and cost-effectiveness of detecting and measuring cells and beads, addressing critical needs in pharmaceutical and biotechnology laboratories globally. As a subsidiary of Sartorius AG, IntelliCyt continues to lead in providing solutions that meet the demands of modern life sciences research while ensuring rapid and relevant results in various applications, including phenotypic small molecule drug discovery and in vitro toxicology.

Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

NeuroLutions Inc. is a company based in St. Louis, Missouri, focused on developing brain-computer interface (BCI) devices aimed at restoring functions for patients disabled due to neurological injuries, particularly stroke survivors. Founded in 2007, NeuroLutions employs non-invasive electroencephalography (EEG) technology to capture brain activity without the need for implanted electrodes. The EEG data is wirelessly transmitted to a tablet, where it is analyzed to interpret the patient's intended muscle movements. This innovative approach enables users to facilitate muscle re-education and helps maintain or improve their range of motion, thereby enhancing rehabilitation outcomes for individuals with movement impairments.

CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

AirXpanders, Inc. was a medical device company founded in 2005 and headquartered in San Jose, California. It specialized in designing, manufacturing, and distributing devices aimed at improving breast reconstruction procedures. The company developed the AeroForm Tissue Expander System, a needle-free, patient-controlled device used for tissue expansion in patients undergoing two-stage breast reconstruction after mastectomy. AirXpanders operated in Australia, the United States, and Europe, focusing on enhancing the experience and outcomes for patients requiring breast reconstruction. However, on September 25, 2019, the company filed for Chapter 7 bankruptcy and ceased operations.

Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

Spindrift Beverage Co., Inc., founded in 2010 and based in Newton, Massachusetts, specializes in producing unsweetened sparkling beverages made with real squeezed fruit. The company offers a range of drinks that combine triple-filtered sparkling water with authentic fruit flavors, such as lemon, raspberry lime, and strawberry, without any artificial sweeteners. Spindrift aims to provide consumers with refreshing beverages that promote a healthy and active lifestyle through the use of real ingredients.

Singulex, Inc. is an immunodiagnostics and biotechnology company that specializes in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company has developed the Sgx Clarity System, an in vitro diagnostics platform capable of detecting low abundance biomarkers at levels down to femtograms/mL. This system assists clinicians in managing cardiovascular health, while also providing heart disease monitoring services and personalized wellness programs for patients. Singulex's offerings include ultra-sensitive immunoassay solutions and laboratory testing services that facilitate both reactive and proactive health management, as well as support the discovery of new therapeutics. The company serves a diverse clientele, including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Additionally, Singulex is involved in pilot studies to validate its Erenna BioAssay System, which enhances molecular detection capabilities. Founded in 1997 and based in Alameda, California, Singulex has an additional office in Basel, Switzerland, and was previously known as BioProfile Corporation until its name change in 2003.

EndoStim, Inc. is a medical device company based in Dallas, Texas, specializing in neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Founded in 2009, the company has developed a microstimulator technology that restores normal esophageal function by targeting the weak or dysfunctional lower esophageal sphincter (LES) muscle. This innovative approach offers long-term control of reflux symptoms while minimizing the gastrointestinal side effects often associated with traditional anti-reflux surgery. EndoStim is actively conducting clinical trials to secure FDA approval for its therapies, which aim to address not only GERD but also urinary urge incontinence. The company distributes its products across Europe, Asia, and Latin America, focusing on improving the quality of life for patients suffering from these conditions.

VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

AirXpanders, Inc. was a medical device company founded in 2005 and headquartered in San Jose, California. It specialized in designing, manufacturing, and distributing devices aimed at improving breast reconstruction procedures. The company developed the AeroForm Tissue Expander System, a needle-free, patient-controlled device used for tissue expansion in patients undergoing two-stage breast reconstruction after mastectomy. AirXpanders operated in Australia, the United States, and Europe, focusing on enhancing the experience and outcomes for patients requiring breast reconstruction. However, on September 25, 2019, the company filed for Chapter 7 bankruptcy and ceased operations.

IntelliCyt Corporation specializes in the development of high-throughput cell- and bead-based screening solutions tailored for the life sciences sector, particularly in drug discovery, antibody development, and immunology. Founded in 2006 and based in Albuquerque, New Mexico, the company offers a comprehensive iQue Screener platform that integrates instrumentation, software, and reagents to facilitate high-content multiplex analysis of samples in liquid suspension. This platform is complemented by ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. IntelliCyt’s innovative technologies significantly enhance the efficiency and cost-effectiveness of detecting and measuring cells and beads, addressing critical needs in pharmaceutical and biotechnology laboratories globally. As a subsidiary of Sartorius AG, IntelliCyt continues to lead in providing solutions that meet the demands of modern life sciences research while ensuring rapid and relevant results in various applications, including phenotypic small molecule drug discovery and in vitro toxicology.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that integrate enzymes into traditional chemical absorption processes, allowing for effective CO2 capture. In addition to its focus on carbon capture, the company has demonstrated capabilities in creating biofuel cells and is exploring commercial applications in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The technology targets a range of industries in the United States, positioning Akermin as a key player in advancing environmentally sustainable practices.

EndoStim, Inc. is a medical device company based in Dallas, Texas, specializing in neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Founded in 2009, the company has developed a microstimulator technology that restores normal esophageal function by targeting the weak or dysfunctional lower esophageal sphincter (LES) muscle. This innovative approach offers long-term control of reflux symptoms while minimizing the gastrointestinal side effects often associated with traditional anti-reflux surgery. EndoStim is actively conducting clinical trials to secure FDA approval for its therapies, which aim to address not only GERD but also urinary urge incontinence. The company distributes its products across Europe, Asia, and Latin America, focusing on improving the quality of life for patients suffering from these conditions.

AirXpanders, Inc. was a medical device company founded in 2005 and headquartered in San Jose, California. It specialized in designing, manufacturing, and distributing devices aimed at improving breast reconstruction procedures. The company developed the AeroForm Tissue Expander System, a needle-free, patient-controlled device used for tissue expansion in patients undergoing two-stage breast reconstruction after mastectomy. AirXpanders operated in Australia, the United States, and Europe, focusing on enhancing the experience and outcomes for patients requiring breast reconstruction. However, on September 25, 2019, the company filed for Chapter 7 bankruptcy and ceased operations.

Zeel is a service that provides on-demand massage therapy, allowing customers to book high-quality massages from licensed and vetted therapists at their homes, hotels, workplaces, or events. Founded in 2012 and launching its app in 2013, Zeel offers massages with a range of options including Swedish, deep tissue, prenatal, sports, and couples massages, available seven days a week, with appointments that can be scheduled as soon as one hour in advance or up to a month ahead. Customers can conveniently book services through the Zeel app for both iOS and Android devices, paying a fixed price that includes tax and gratuity. All massage therapists are thoroughly vetted, licensed, insured, and trained by Zeel to ensure a high standard of service. In 2013, Zeel introduced Massage Zeelot, a subscription service that provides customers with monthly in-home massages at a discounted rate, along with a free professional massage table.

Singulex, Inc. is an immunodiagnostics and biotechnology company that specializes in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company has developed the Sgx Clarity System, an in vitro diagnostics platform capable of detecting low abundance biomarkers at levels down to femtograms/mL. This system assists clinicians in managing cardiovascular health, while also providing heart disease monitoring services and personalized wellness programs for patients. Singulex's offerings include ultra-sensitive immunoassay solutions and laboratory testing services that facilitate both reactive and proactive health management, as well as support the discovery of new therapeutics. The company serves a diverse clientele, including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Additionally, Singulex is involved in pilot studies to validate its Erenna BioAssay System, which enhances molecular detection capabilities. Founded in 1997 and based in Alameda, California, Singulex has an additional office in Basel, Switzerland, and was previously known as BioProfile Corporation until its name change in 2003.

AirXpanders, Inc. was a medical device company founded in 2005 and headquartered in San Jose, California. It specialized in designing, manufacturing, and distributing devices aimed at improving breast reconstruction procedures. The company developed the AeroForm Tissue Expander System, a needle-free, patient-controlled device used for tissue expansion in patients undergoing two-stage breast reconstruction after mastectomy. AirXpanders operated in Australia, the United States, and Europe, focusing on enhancing the experience and outcomes for patients requiring breast reconstruction. However, on September 25, 2019, the company filed for Chapter 7 bankruptcy and ceased operations.

The Nest Collective, Inc. produces organic food and snacks for babies, toddlers, and kids. The company was incorporated in 2008 and is based in Emeryville, California.

EndoStim, Inc. is a medical device company based in Dallas, Texas, specializing in neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Founded in 2009, the company has developed a microstimulator technology that restores normal esophageal function by targeting the weak or dysfunctional lower esophageal sphincter (LES) muscle. This innovative approach offers long-term control of reflux symptoms while minimizing the gastrointestinal side effects often associated with traditional anti-reflux surgery. EndoStim is actively conducting clinical trials to secure FDA approval for its therapies, which aim to address not only GERD but also urinary urge incontinence. The company distributes its products across Europe, Asia, and Latin America, focusing on improving the quality of life for patients suffering from these conditions.

Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

EndoStim, Inc. is a medical device company based in Dallas, Texas, specializing in neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Founded in 2009, the company has developed a microstimulator technology that restores normal esophageal function by targeting the weak or dysfunctional lower esophageal sphincter (LES) muscle. This innovative approach offers long-term control of reflux symptoms while minimizing the gastrointestinal side effects often associated with traditional anti-reflux surgery. EndoStim is actively conducting clinical trials to secure FDA approval for its therapies, which aim to address not only GERD but also urinary urge incontinence. The company distributes its products across Europe, Asia, and Latin America, focusing on improving the quality of life for patients suffering from these conditions.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that integrate enzymes into traditional chemical absorption processes, allowing for effective CO2 capture. In addition to its focus on carbon capture, the company has demonstrated capabilities in creating biofuel cells and is exploring commercial applications in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The technology targets a range of industries in the United States, positioning Akermin as a key player in advancing environmentally sustainable practices.

Plum Organics is a leading brand in organic baby food and toddler snacks, committed to promoting healthy eating habits from an early age. The company offers a range of culinary-inspired baby foods in three stages, all gently cooked to preserve optimal nutrition. Plum Organics prioritizes sustainability, focusing on reducing its carbon footprint through responsible ingredient sourcing and packaging choices. Their product line includes pouch purees, finger foods, and lunchbox snacks, providing convenient and nutritious options for parents.

Divergence is a research and development company focused on creating effective and environmentally sustainable methods for controlling parasites and pests, particularly parasitic nematodes. These roundworms are significant agricultural pests, inflicting billions of dollars in damage to various crops, such as soybeans, corn, cotton, strawberries, and bananas. Additionally, some nematodes are responsible for serious human diseases, including hookworm, whipworm, and roundworm infections, as well as filarial infections that lead to lymphatic filariasis and onchocerciasis. By developing innovative genes and molecules, Divergence aims to address the challenges posed by these harmful organisms in both agricultural and medical contexts.

Veran Medical Technologies is a medical device company focused on developing minimally invasive solutions for interventional oncology procedures. Based in St. Louis, Missouri, the company offers a range of products, including the SPiNView thoracic navigation system, which aids physicians in performing biopsies on solitary pulmonary nodules for early lung cancer diagnosis. Other key offerings include the ig4 IR System, a platform that assists in biopsies and ablations for various organs, and the SPiNPerc device for hybrid diagnostic procedures. The company also provides vPad2, a tracking device for instrument positioning during surgery, and the vTrack 2.0 Instruments, which guide physicians to peripheral lung regions. Veran's technology enhances diagnostic accuracy and therapy delivery by integrating various imaging modalities, ultimately aiming to improve patient outcomes through earlier cancer detection and treatment.

Asoyia, LLC is a company that specializes in the production of soybeans and soybean oil. Founded in 2004 and based in Iowa City, Iowa, Asoyia serves various sectors including food processors, institutional food management, and restaurant chains. The company's products are distributed through a network of distributors and are available from its locations in Des Moines and Cedar Rapids, Iowa, as well as Bloomington, Illinois.

CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that integrate enzymes into traditional chemical absorption processes, allowing for effective CO2 capture. In addition to its focus on carbon capture, the company has demonstrated capabilities in creating biofuel cells and is exploring commercial applications in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The technology targets a range of industries in the United States, positioning Akermin as a key player in advancing environmentally sustainable practices.

Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Singulex, Inc. is an immunodiagnostics and biotechnology company that specializes in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company has developed the Sgx Clarity System, an in vitro diagnostics platform capable of detecting low abundance biomarkers at levels down to femtograms/mL. This system assists clinicians in managing cardiovascular health, while also providing heart disease monitoring services and personalized wellness programs for patients. Singulex's offerings include ultra-sensitive immunoassay solutions and laboratory testing services that facilitate both reactive and proactive health management, as well as support the discovery of new therapeutics. The company serves a diverse clientele, including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Additionally, Singulex is involved in pilot studies to validate its Erenna BioAssay System, which enhances molecular detection capabilities. Founded in 1997 and based in Alameda, California, Singulex has an additional office in Basel, Switzerland, and was previously known as BioProfile Corporation until its name change in 2003.

Dreamerz Foods, Inc. provides various natural sleep products. It offers natural sleep beverage, a dietary supplement in the form of an all-natural, creamy, and dairy-based functional sleep beverage. The company also provides chocolate pillows, soothing dairy products, and herbal fruit-flavored mix. It offers its products through stores and online shops. Dreamerz Foods, Inc. was founded in 2006 and is based in San Francisco, California.

The Natural Dentist, Inc., founded in 1995 and based in Medford, Massachusetts, specializes in manufacturing oral care products, including mouth rinses and toothpastes. The company, which was previously known as Woodstock Natural Products Inc. before rebranding in 2005, provides its products through various retail channels, including physical stores and online platforms. In 2010, The Natural Dentist was acquired by Revive Personal Products Company. The company is part of a broader portfolio that includes over-the-counter consumer healthcare brands, reflecting its commitment to promoting oral health and hygiene.

Attune Foods, Inc. is a producer of organic snacks, headquartered in San Francisco, California, with additional operations in Eugene, Oregon. Established in 2006, the company specializes in probiotic wellness bars available in a variety of flavors, including dark chocolate, chocolate crisp, and mint chocolate, among others. In addition to these bars, Attune Foods offers a range of products such as granolas featuring chocolate or yogurt chips, muesli, cereal products, and graham crackers. The company's focus is on providing customized healthy food options to support consumer wellness.

AirXpanders, Inc. was a medical device company founded in 2005 and headquartered in San Jose, California. It specialized in designing, manufacturing, and distributing devices aimed at improving breast reconstruction procedures. The company developed the AeroForm Tissue Expander System, a needle-free, patient-controlled device used for tissue expansion in patients undergoing two-stage breast reconstruction after mastectomy. AirXpanders operated in Australia, the United States, and Europe, focusing on enhancing the experience and outcomes for patients requiring breast reconstruction. However, on September 25, 2019, the company filed for Chapter 7 bankruptcy and ceased operations.

AirXpanders, Inc. was a medical device company founded in 2005 and headquartered in San Jose, California. It specialized in designing, manufacturing, and distributing devices aimed at improving breast reconstruction procedures. The company developed the AeroForm Tissue Expander System, a needle-free, patient-controlled device used for tissue expansion in patients undergoing two-stage breast reconstruction after mastectomy. AirXpanders operated in Australia, the United States, and Europe, focusing on enhancing the experience and outcomes for patients requiring breast reconstruction. However, on September 25, 2019, the company filed for Chapter 7 bankruptcy and ceased operations.

Dreamerz Foods, Inc. provides various natural sleep products. It offers natural sleep beverage, a dietary supplement in the form of an all-natural, creamy, and dairy-based functional sleep beverage. The company also provides chocolate pillows, soothing dairy products, and herbal fruit-flavored mix. It offers its products through stores and online shops. Dreamerz Foods, Inc. was founded in 2006 and is based in San Francisco, California.

The Natural Dentist, Inc., founded in 1995 and based in Medford, Massachusetts, specializes in manufacturing oral care products, including mouth rinses and toothpastes. The company, which was previously known as Woodstock Natural Products Inc. before rebranding in 2005, provides its products through various retail channels, including physical stores and online platforms. In 2010, The Natural Dentist was acquired by Revive Personal Products Company. The company is part of a broader portfolio that includes over-the-counter consumer healthcare brands, reflecting its commitment to promoting oral health and hygiene.

Travanti Pharma is a privately held company that focuses on the design, development, and marketing of innovative drug delivery platforms aimed at enhancing the safety, compliance, effectiveness, and ease of medication administration. The company's technology includes an electronic drug delivery system that employs controlled low-level electrical energy to safely transport drugs through the skin or other areas of the body. Additionally, Travanti Pharma offers a wearable electronic disposable drug delivery system, which is a portable and disposable solution for transdermal medication delivery. Through these advanced technologies, Travanti Pharma seeks to improve patient outcomes and streamline the drug delivery process.

Singulex, Inc. is an immunodiagnostics and biotechnology company that specializes in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company has developed the Sgx Clarity System, an in vitro diagnostics platform capable of detecting low abundance biomarkers at levels down to femtograms/mL. This system assists clinicians in managing cardiovascular health, while also providing heart disease monitoring services and personalized wellness programs for patients. Singulex's offerings include ultra-sensitive immunoassay solutions and laboratory testing services that facilitate both reactive and proactive health management, as well as support the discovery of new therapeutics. The company serves a diverse clientele, including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Additionally, Singulex is involved in pilot studies to validate its Erenna BioAssay System, which enhances molecular detection capabilities. Founded in 1997 and based in Alameda, California, Singulex has an additional office in Basel, Switzerland, and was previously known as BioProfile Corporation until its name change in 2003.

EraGen Biosciences, Inc. is a biotechnology company based in Madison, Wisconsin, that specializes in developing, manufacturing, and marketing molecular reagent products and software for research and clinical testing markets. The company provides molecular diagnostic assays designed for the early detection and monitoring of cancer, genetic disorders, infectious diseases, and other genetic-based conditions. Its product offerings include molecular diagnostic tests, analyte specific reagents, in vitro diagnostic reagents, and research use only reagents. Additionally, EraGen Biosciences offers MultiCode-PLx and MultiCode-RTx Analysis Software, which enable users to create customized templates for assay layouts and conduct quantitative and qualitative analyses, respectively. The company primarily serves clinical laboratories and medical researchers, distributing its products across the United States and Canada. Founded in 1994 as Sulfonics, Inc., it adopted the name EraGen Biosciences, Inc. in 1999.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that integrate enzymes into traditional chemical absorption processes, allowing for effective CO2 capture. In addition to its focus on carbon capture, the company has demonstrated capabilities in creating biofuel cells and is exploring commercial applications in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The technology targets a range of industries in the United States, positioning Akermin as a key player in advancing environmentally sustainable practices.

Kereos, Inc. is a biopharmaceutical company based in Saint Louis, Missouri, specializing in the development of targeted molecular imaging agents and therapeutics aimed at detecting and treating cancer and cardiovascular diseases. Established in 1999, Kereos utilizes a nanoscale drug delivery technology that enhances the targeting and efficacy of various therapeutic compounds, including existing drugs, new candidates, and those that may be too toxic or fragile for conventional delivery methods. The company's product portfolio includes KER-1001, a cancer therapeutic that combines paclitaxel with a targeted nanodroplet, KER-1002, which integrates a natural anti-tumor agent, and KER-1003, known for its anti-angiogenic properties. Additionally, Kereos offers diagnostic solutions such as KER 0001, designed to detect angiogenesis. The company also collaborates with pharmaceutical and imaging firms to further develop its MRI agents and targeted chemotherapeutics for solid tumors and cardiovascular applications.

Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

Brand New Brands is a groundbreaking new company that brings together the entrepreneurial spirit of a start-up and the resources of an established corporation to create new foods and beverages that promote health and wellness. Brand New Brands uses a portfolio-based incubator model to develop and market the highest potential new functional food business opportunities for the U.S. marketplace. Core to their approach is the commitment to create food and beverage products that are efficacious (by medical standards), honest and transparent in their claims, and satisfying to eat or drink. By vetting and assessing the potential of scores of new product concepts, they take the most promising opportunities and fuse them with talented, passionate and proven entrepreneurial teams who turn ideas into thriving new ventures. They focus their efforts and resources by innovating “category-creating” brand platforms that are capable of crossing over from niche markets to the mainstream in three to five years. They only pursue opportunities where they can claim distinct competitive advantages over large food companies through IP, brand creation or non-traditional distribution. Their strategy is to take the most promising new nutritional technologies and deliver them to the marketplace through great-tasting products with engaging “lifestyle” brands that educate and attract loyal customers and progressive retail partners. They take opportunities to market that are likely to scale quickly due to the convergence of scientific advances, consumer readiness and media attention.

Travanti Pharma is a privately held company that focuses on the design, development, and marketing of innovative drug delivery platforms aimed at enhancing the safety, compliance, effectiveness, and ease of medication administration. The company's technology includes an electronic drug delivery system that employs controlled low-level electrical energy to safely transport drugs through the skin or other areas of the body. Additionally, Travanti Pharma offers a wearable electronic disposable drug delivery system, which is a portable and disposable solution for transdermal medication delivery. Through these advanced technologies, Travanti Pharma seeks to improve patient outcomes and streamline the drug delivery process.

ZyStor Therapeutics, Inc. is a privately-held biotechnology company focused on developing enzyme replacement therapies for lysosomal storage diseases. The company specializes in creating innovative replacement technologies that enhance the delivery of therapeutics designed to substitute for missing lysosomal enzymes. These therapies aim to address the needs of patients suffering from genetic disorders characterized by lysosomal storage dysfunction.

Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

Efficas, Inc., based in Boulder, Colorado, is a health science and technology company that specializes in the research, development, and commercialization of products aimed at nutritional management of the immune system for both humans and pets. Founded in 2003, the company offers EFFICAS CARE, a berry-flavored non-prescription medical food designed to assist in the dietary management of asthma and related allergies. Efficas focuses on creating effective solutions that work with the body's natural systems, providing safe and significant health benefits to patients suffering from asthma and allergic conditions.

Divergence is a research and development company focused on creating effective and environmentally sustainable methods for controlling parasites and pests, particularly parasitic nematodes. These roundworms are significant agricultural pests, inflicting billions of dollars in damage to various crops, such as soybeans, corn, cotton, strawberries, and bananas. Additionally, some nematodes are responsible for serious human diseases, including hookworm, whipworm, and roundworm infections, as well as filarial infections that lead to lymphatic filariasis and onchocerciasis. By developing innovative genes and molecules, Divergence aims to address the challenges posed by these harmful organisms in both agricultural and medical contexts.

Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Divergence is a research and development company focused on creating effective and environmentally sustainable methods for controlling parasites and pests, particularly parasitic nematodes. These roundworms are significant agricultural pests, inflicting billions of dollars in damage to various crops, such as soybeans, corn, cotton, strawberries, and bananas. Additionally, some nematodes are responsible for serious human diseases, including hookworm, whipworm, and roundworm infections, as well as filarial infections that lead to lymphatic filariasis and onchocerciasis. By developing innovative genes and molecules, Divergence aims to address the challenges posed by these harmful organisms in both agricultural and medical contexts.

Inoveon Corporation is a medical services company based in Oklahoma City, Oklahoma, focused on providing solutions for the detection, staging, and monitoring of eye diseases, specifically diabetic retinopathy, macular degeneration, and glaucoma. Founded in 1997, Inoveon offers advanced technologies, including iScan, which assesses diabetic retinopathy and macular edema, and the INOVEON System, designed to enhance compliance rates among physician groups for managing these conditions. As a subsidiary of Ifa Systems Ag since 2010, Inoveon aims to support healthcare providers in delivering quality care to patients with eye-related diseases, ultimately working to preserve eyesight.