Prolog Ventures

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

CleanSlate UV is a company that develops sanitization devices specifically designed to disinfect smartphones and other portable electronics. By leveraging the power of UV light, CleanSlate UV aims to eliminate harmful pathogens on mobile devices, which is particularly important in healthcare settings to reduce the risk of hospital-acquired infections. The company's technology provides users with an effective and easy-to-use solution for sanitizing their personal items while maintaining hand hygiene. Additionally, CleanSlate UV's devices collect data on sanitization compliance, enabling businesses to effectively address the growing challenge of device hygiene. The mission of the company centers on enhancing health safety by ensuring that mobile devices are free from dangerous bacteria without causing any damage to sensitive screens.

CoverCress Inc. is a biotechnology company based in Saint Louis, Missouri, founded in 2013. The company focuses on developing and commercializing field pennycress as an oilseed crop, which is utilized for producing oil for renewable fuels and meal for livestock feed. By genetically improving pennycress, CoverCress aims to create a sustainable cover crop that enhances soil health and offers benefits for farmers during corn and soybean planting seasons. The company’s efforts are centered on sustainable agricultural practices, allowing farmers to maximize yields while minimizing input and carbon emissions. Formerly known as Arvegenix Inc., CoverCress reflects a commitment to innovation in agriculture, biotechnology, and renewable energy solutions.

Kinnos Inc. is a biotechnology company based in Brooklyn, New York, that specializes in innovative color technology to enhance disinfection practices. Founded in 2014, the company manufactures Highlight, a patent-pending powdered additive that improves the visibility of disinfectants, thereby increasing user compliance and ensuring thorough cleaning. Highlight provides real-time color-change feedback, empowering individuals to disinfect surfaces with confidence. In addition to the Highlight additive, Kinnos offers Highlight Wipes, a dispensing machine for wipes, and Highlight Powder, a disinfectant additive. The company's mission is to transform how disinfectants are used, ultimately aiming to prevent disease outbreaks and promote public health through visible disinfection.

Kinnos Inc. is a biotechnology company based in Brooklyn, New York, that specializes in innovative color technology to enhance disinfection practices. Founded in 2014, the company manufactures Highlight, a patent-pending powdered additive that improves the visibility of disinfectants, thereby increasing user compliance and ensuring thorough cleaning. Highlight provides real-time color-change feedback, empowering individuals to disinfect surfaces with confidence. In addition to the Highlight additive, Kinnos offers Highlight Wipes, a dispensing machine for wipes, and Highlight Powder, a disinfectant additive. The company's mission is to transform how disinfectants are used, ultimately aiming to prevent disease outbreaks and promote public health through visible disinfection.

BioClarity is a company focused on addressing the skincare concerns of young adults. It operates an online marketplace specializing in acne treatment products for women, offering a range of botanical, plant-rich skincare items that are clinically proven to reduce redness and pore size. The company's mission is to provide affordable, chemical-free beauty solutions that fuse nature and science, aiming to create the next generation of acne-fighting products.

SchoolCare is a digital health platform that provides free health technology to K-12 public schools, enabling school nurses to deliver effective care and enhance student safety. The company aims to create a unified health record for every family by leveraging pediatric health data within the extensive K-12 school system, which serves as a vital public health infrastructure. SchoolCare's platform captures essential student medical information, including charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. By addressing gaps in traditional care coordination, SchoolCare ensures that crucial care instructions reach school nurses, thereby reducing the risk of inconsistent post-discharge care. Through its innovative approach, SchoolCare seeks to improve health outcomes for children and streamline public school health programs across the United States.

CoverCress Inc. is a biotechnology company based in Saint Louis, Missouri, founded in 2013. The company focuses on developing and commercializing field pennycress as an oilseed crop, which is utilized for producing oil for renewable fuels and meal for livestock feed. By genetically improving pennycress, CoverCress aims to create a sustainable cover crop that enhances soil health and offers benefits for farmers during corn and soybean planting seasons. The company’s efforts are centered on sustainable agricultural practices, allowing farmers to maximize yields while minimizing input and carbon emissions. Formerly known as Arvegenix Inc., CoverCress reflects a commitment to innovation in agriculture, biotechnology, and renewable energy solutions.

TOMA Biosciences, Inc. is a genomics company based in Foster City, California, that specializes in developing reagent kits and sequencing solutions to identify genomic alterations in cancer tumors. Founded in 2011, TOMA offers TOMA OS-Seq, an oncology-focused gene analysis product that leverages next-generation sequencing technology to detect clinically significant changes in tumor DNA. This information is crucial for physicians as it aids in optimizing treatment plans for cancer patients. By providing laboratories, hospital systems, and research institutions with tools to uncover DNA alterations in cancer cells, TOMA enhances the ability of clinicians and researchers to make informed decisions regarding treatment options.

Spindrift Beverage Co., Inc., established in 2010 and headquartered in Newton, Massachusetts, specializes in producing and supplying non-alcoholic beverages. Its product portfolio includes a variety of sodas in flavors like grapefruit, blackberry, and orange, as well as flavored sparkling water and seltzers. Spindrift's beverages are notable for using real squeezed fruit, with no added artificial sweeteners, providing consumers with a healthier, fruit-driven alternative. The company sells its products through distributors, retail stores, and online platforms across the United States.

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

Spindrift Beverage Co., Inc., established in 2010 and headquartered in Newton, Massachusetts, specializes in producing and supplying non-alcoholic beverages. Its product portfolio includes a variety of sodas in flavors like grapefruit, blackberry, and orange, as well as flavored sparkling water and seltzers. Spindrift's beverages are notable for using real squeezed fruit, with no added artificial sweeteners, providing consumers with a healthier, fruit-driven alternative. The company sells its products through distributors, retail stores, and online platforms across the United States.

CoverCress Inc. is a biotechnology company based in Saint Louis, Missouri, founded in 2013. The company focuses on developing and commercializing field pennycress as an oilseed crop, which is utilized for producing oil for renewable fuels and meal for livestock feed. By genetically improving pennycress, CoverCress aims to create a sustainable cover crop that enhances soil health and offers benefits for farmers during corn and soybean planting seasons. The company’s efforts are centered on sustainable agricultural practices, allowing farmers to maximize yields while minimizing input and carbon emissions. Formerly known as Arvegenix Inc., CoverCress reflects a commitment to innovation in agriculture, biotechnology, and renewable energy solutions.

SchoolCare is a digital health platform that provides free health technology to K-12 public schools, enabling school nurses to deliver effective care and enhance student safety. The company aims to create a unified health record for every family by leveraging pediatric health data within the extensive K-12 school system, which serves as a vital public health infrastructure. SchoolCare's platform captures essential student medical information, including charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. By addressing gaps in traditional care coordination, SchoolCare ensures that crucial care instructions reach school nurses, thereby reducing the risk of inconsistent post-discharge care. Through its innovative approach, SchoolCare seeks to improve health outcomes for children and streamline public school health programs across the United States.

SchoolCare is a digital health platform that provides free health technology to K-12 public schools, enabling school nurses to deliver effective care and enhance student safety. The company aims to create a unified health record for every family by leveraging pediatric health data within the extensive K-12 school system, which serves as a vital public health infrastructure. SchoolCare's platform captures essential student medical information, including charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. By addressing gaps in traditional care coordination, SchoolCare ensures that crucial care instructions reach school nurses, thereby reducing the risk of inconsistent post-discharge care. Through its innovative approach, SchoolCare seeks to improve health outcomes for children and streamline public school health programs across the United States.

IntelliCyt Corporation, founded in 2006 and based in Albuquerque, New Mexico, specializes in developing high-throughput cell and bead-based screening solutions for the life sciences sector. The company utilizes proprietary technologies to create its iQue Screener platform, which integrates instruments, software, and reagents for multiplexed analysis of samples in liquid suspension. IntelliCyt's offerings include ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. These products cater to the needs of pharmaceutical and biotechnology companies, as well as medical centers, by significantly increasing the speed and efficiency of detecting and measuring cells and beads. The company addresses critical demands in drug discovery, antibody discovery, and in vitro toxicology, providing earlier and more relevant results while reducing costs. IntelliCyt operates as a subsidiary of Sartorius AG and is recognized for pioneering high-throughput screening technologies that enhance productivity in modern life sciences research.

Veran Medical Technologies, Inc. is a medical device company specializing in minimally invasive therapeutic devices for interventional oncology. Headquartered in St. Louis, Missouri, the company focuses on developing products that assist physicians in diagnosing diseases and delivering targeted therapies. Its offerings include the SPiNView thoracic navigation system, an electromagnetic device designed for the biopsy of solitary pulmonary nodules, and the ig4 IR System, which aids in performing biopsies and other procedures for the lungs, liver, and kidneys. Additionally, Veran Medical provides various instruments such as the vPad2 tracker device and the SPiNPerc hybrid diagnostic tool. The company's innovative solutions utilize advanced imaging technologies to create dynamic 3D maps of respiratory pathways, enhancing procedural planning and navigation, ultimately helping clinicians to expedite cancer diagnosis and treatment. Founded in 2003, Veran Medical Technologies is committed to improving patient outcomes through precision-guided interventions.

Benson Hill is an agricultural technology company that specializes in crop improvement and soy protein innovation. The company focuses on unlocking the natural genetic diversity of plants to develop healthier, more sustainable food and ingredients. Its proprietary CropOS platform leverages machine learning and big data alongside traditional breeding techniques to streamline and expedite the product development process. Benson Hill operates a Crop Accelerator designed for rapid prototyping and is actively developing a seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. The company generates revenue from both proprietary and non-proprietary product categories, with proprietary revenue stemming from the sale of its unique bean varieties.

NeuroLutions Inc., established in 2007 and headquartered in St. Louis, Missouri, specializes in developing non-invasive brain-computer interface (BCI) devices. These devices utilize electroencephalography (EEG) technology to interpret intended muscle movements from the brain, enabling stroke survivors to restore lost arm function and improve range of motion through muscle re-education. The company aims to revolutionize neurorehabilitation by providing a non-invasive alternative to traditional invasive BCI therapies.

CoverCress Inc. is a biotechnology company based in Saint Louis, Missouri, founded in 2013. The company focuses on developing and commercializing field pennycress as an oilseed crop, which is utilized for producing oil for renewable fuels and meal for livestock feed. By genetically improving pennycress, CoverCress aims to create a sustainable cover crop that enhances soil health and offers benefits for farmers during corn and soybean planting seasons. The company’s efforts are centered on sustainable agricultural practices, allowing farmers to maximize yields while minimizing input and carbon emissions. Formerly known as Arvegenix Inc., CoverCress reflects a commitment to innovation in agriculture, biotechnology, and renewable energy solutions.

VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

Veran Medical Technologies, Inc. is a medical device company specializing in minimally invasive therapeutic devices for interventional oncology. Headquartered in St. Louis, Missouri, the company focuses on developing products that assist physicians in diagnosing diseases and delivering targeted therapies. Its offerings include the SPiNView thoracic navigation system, an electromagnetic device designed for the biopsy of solitary pulmonary nodules, and the ig4 IR System, which aids in performing biopsies and other procedures for the lungs, liver, and kidneys. Additionally, Veran Medical provides various instruments such as the vPad2 tracker device and the SPiNPerc hybrid diagnostic tool. The company's innovative solutions utilize advanced imaging technologies to create dynamic 3D maps of respiratory pathways, enhancing procedural planning and navigation, ultimately helping clinicians to expedite cancer diagnosis and treatment. Founded in 2003, Veran Medical Technologies is committed to improving patient outcomes through precision-guided interventions.

AirXpanders, Inc. was a medical device company headquartered in San Jose, California, specializing in the design, manufacture, sale, and distribution of innovative medical devices aimed at improving breast reconstruction outcomes. Founded in 2005, the company developed the AeroForm Tissue Expander System, a needle-free and patient-controlled device specifically designed for use in two-stage breast reconstruction following mastectomy. This system allowed patients to expand tissue in a controlled manner before the insertion of breast implants. Despite its advancements in medical technology, AirXpanders filed for Chapter 7 bankruptcy and ceased operations on September 25, 2019.

Veran Medical Technologies, Inc. is a medical device company specializing in minimally invasive therapeutic devices for interventional oncology. Headquartered in St. Louis, Missouri, the company focuses on developing products that assist physicians in diagnosing diseases and delivering targeted therapies. Its offerings include the SPiNView thoracic navigation system, an electromagnetic device designed for the biopsy of solitary pulmonary nodules, and the ig4 IR System, which aids in performing biopsies and other procedures for the lungs, liver, and kidneys. Additionally, Veran Medical provides various instruments such as the vPad2 tracker device and the SPiNPerc hybrid diagnostic tool. The company's innovative solutions utilize advanced imaging technologies to create dynamic 3D maps of respiratory pathways, enhancing procedural planning and navigation, ultimately helping clinicians to expedite cancer diagnosis and treatment. Founded in 2003, Veran Medical Technologies is committed to improving patient outcomes through precision-guided interventions.

Spindrift Beverage Co., Inc., established in 2010 and headquartered in Newton, Massachusetts, specializes in producing and supplying non-alcoholic beverages. Its product portfolio includes a variety of sodas in flavors like grapefruit, blackberry, and orange, as well as flavored sparkling water and seltzers. Spindrift's beverages are notable for using real squeezed fruit, with no added artificial sweeteners, providing consumers with a healthier, fruit-driven alternative. The company sells its products through distributors, retail stores, and online platforms across the United States.

Singulex, Inc. is an immunodiagnostics company specializing in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company develops the Sgx Clarity System, an advanced in vitro diagnostics platform that detects low abundance biomarkers with high sensitivity, down to femtograms per milliliter. This system supports cardiovascular health management through services aimed at clinicians and personalized wellness programs for patients. Singulex offers ultra-sensitive immunoassay solutions and laboratory testing services that enhance patient care by facilitating proactive health management and aiding in the discovery of new therapeutics. The company serves a diverse clientele including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Singulex, originally established as BioProfile Corporation in 1997, rebranded in 2003 and is headquartered in Alameda, California, with an additional office in Basel, Switzerland.

EndoStim Inc., established in 2009 and headquartered in Dallas, Texas, is a medical device company specializing in neurostimulation solutions for treating gastro-esophageal reflux disease (GERD). The company's primary product is a microstimulator that targets the lower esophageal sphincter muscle to restore normal function, providing long-term reflux control. EndoStim distributes its products globally, with a presence in Europe, Asia, and Latin America. Currently, it is conducting clinical trials to pursue FDA approval for this innovative treatment option.

VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

AirXpanders, Inc. was a medical device company headquartered in San Jose, California, specializing in the design, manufacture, sale, and distribution of innovative medical devices aimed at improving breast reconstruction outcomes. Founded in 2005, the company developed the AeroForm Tissue Expander System, a needle-free and patient-controlled device specifically designed for use in two-stage breast reconstruction following mastectomy. This system allowed patients to expand tissue in a controlled manner before the insertion of breast implants. Despite its advancements in medical technology, AirXpanders filed for Chapter 7 bankruptcy and ceased operations on September 25, 2019.

IntelliCyt Corporation, founded in 2006 and based in Albuquerque, New Mexico, specializes in developing high-throughput cell and bead-based screening solutions for the life sciences sector. The company utilizes proprietary technologies to create its iQue Screener platform, which integrates instruments, software, and reagents for multiplexed analysis of samples in liquid suspension. IntelliCyt's offerings include ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. These products cater to the needs of pharmaceutical and biotechnology companies, as well as medical centers, by significantly increasing the speed and efficiency of detecting and measuring cells and beads. The company addresses critical demands in drug discovery, antibody discovery, and in vitro toxicology, providing earlier and more relevant results while reducing costs. IntelliCyt operates as a subsidiary of Sartorius AG and is recognized for pioneering high-throughput screening technologies that enhance productivity in modern life sciences research.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that enable the integration of enzymes into traditional chemical absorption processes for effective CO2 removal. In addition to its primary focus on carbon capture, Akermin is also exploring applications of its stabilized enzyme technology in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The company aims to commercialize its technology, which originated from research at Saint Louis University, and has demonstrated its capabilities in developing sustainable solutions for a range of industries.

EndoStim Inc., established in 2009 and headquartered in Dallas, Texas, is a medical device company specializing in neurostimulation solutions for treating gastro-esophageal reflux disease (GERD). The company's primary product is a microstimulator that targets the lower esophageal sphincter muscle to restore normal function, providing long-term reflux control. EndoStim distributes its products globally, with a presence in Europe, Asia, and Latin America. Currently, it is conducting clinical trials to pursue FDA approval for this innovative treatment option.

AirXpanders, Inc. was a medical device company headquartered in San Jose, California, specializing in the design, manufacture, sale, and distribution of innovative medical devices aimed at improving breast reconstruction outcomes. Founded in 2005, the company developed the AeroForm Tissue Expander System, a needle-free and patient-controlled device specifically designed for use in two-stage breast reconstruction following mastectomy. This system allowed patients to expand tissue in a controlled manner before the insertion of breast implants. Despite its advancements in medical technology, AirXpanders filed for Chapter 7 bankruptcy and ceased operations on September 25, 2019.

Zeel is a service that provides on-demand massage therapy, allowing customers to book high-quality massages from licensed and vetted therapists at their homes, hotels, workplaces, or events. Founded in 2012 and launching its app in 2013, Zeel offers massages with a range of options including Swedish, deep tissue, prenatal, sports, and couples massages, available seven days a week, with appointments that can be scheduled as soon as one hour in advance or up to a month ahead. Customers can conveniently book services through the Zeel app for both iOS and Android devices, paying a fixed price that includes tax and gratuity. All massage therapists are thoroughly vetted, licensed, insured, and trained by Zeel to ensure a high standard of service. In 2013, Zeel introduced Massage Zeelot, a subscription service that provides customers with monthly in-home massages at a discounted rate, along with a free professional massage table.

Singulex, Inc. is an immunodiagnostics company specializing in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company develops the Sgx Clarity System, an advanced in vitro diagnostics platform that detects low abundance biomarkers with high sensitivity, down to femtograms per milliliter. This system supports cardiovascular health management through services aimed at clinicians and personalized wellness programs for patients. Singulex offers ultra-sensitive immunoassay solutions and laboratory testing services that enhance patient care by facilitating proactive health management and aiding in the discovery of new therapeutics. The company serves a diverse clientele including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Singulex, originally established as BioProfile Corporation in 1997, rebranded in 2003 and is headquartered in Alameda, California, with an additional office in Basel, Switzerland.

AirXpanders, Inc. was a medical device company headquartered in San Jose, California, specializing in the design, manufacture, sale, and distribution of innovative medical devices aimed at improving breast reconstruction outcomes. Founded in 2005, the company developed the AeroForm Tissue Expander System, a needle-free and patient-controlled device specifically designed for use in two-stage breast reconstruction following mastectomy. This system allowed patients to expand tissue in a controlled manner before the insertion of breast implants. Despite its advancements in medical technology, AirXpanders filed for Chapter 7 bankruptcy and ceased operations on September 25, 2019.

The Nest Collective, Inc. produces organic food and snacks for babies, toddlers, and kids. The company was incorporated in 2008 and is based in Emeryville, California.

EndoStim Inc., established in 2009 and headquartered in Dallas, Texas, is a medical device company specializing in neurostimulation solutions for treating gastro-esophageal reflux disease (GERD). The company's primary product is a microstimulator that targets the lower esophageal sphincter muscle to restore normal function, providing long-term reflux control. EndoStim distributes its products globally, with a presence in Europe, Asia, and Latin America. Currently, it is conducting clinical trials to pursue FDA approval for this innovative treatment option.

Veran Medical Technologies, Inc. is a medical device company specializing in minimally invasive therapeutic devices for interventional oncology. Headquartered in St. Louis, Missouri, the company focuses on developing products that assist physicians in diagnosing diseases and delivering targeted therapies. Its offerings include the SPiNView thoracic navigation system, an electromagnetic device designed for the biopsy of solitary pulmonary nodules, and the ig4 IR System, which aids in performing biopsies and other procedures for the lungs, liver, and kidneys. Additionally, Veran Medical provides various instruments such as the vPad2 tracker device and the SPiNPerc hybrid diagnostic tool. The company's innovative solutions utilize advanced imaging technologies to create dynamic 3D maps of respiratory pathways, enhancing procedural planning and navigation, ultimately helping clinicians to expedite cancer diagnosis and treatment. Founded in 2003, Veran Medical Technologies is committed to improving patient outcomes through precision-guided interventions.

VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

EndoStim Inc., established in 2009 and headquartered in Dallas, Texas, is a medical device company specializing in neurostimulation solutions for treating gastro-esophageal reflux disease (GERD). The company's primary product is a microstimulator that targets the lower esophageal sphincter muscle to restore normal function, providing long-term reflux control. EndoStim distributes its products globally, with a presence in Europe, Asia, and Latin America. Currently, it is conducting clinical trials to pursue FDA approval for this innovative treatment option.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that enable the integration of enzymes into traditional chemical absorption processes for effective CO2 removal. In addition to its primary focus on carbon capture, Akermin is also exploring applications of its stabilized enzyme technology in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The company aims to commercialize its technology, which originated from research at Saint Louis University, and has demonstrated its capabilities in developing sustainable solutions for a range of industries.

Plum Organics is a leading brand in organic baby food and toddler snacks, committed to promoting healthy eating habits from an early age. The company offers a range of culinary-inspired baby foods in three stages, all gently cooked to preserve optimal nutrition. Plum Organics prioritizes sustainability, focusing on reducing its carbon footprint through responsible ingredient sourcing and packaging choices. Their product line includes pouch purees, finger foods, and lunchbox snacks, providing convenient and nutritious options for parents.

Divergence is a research and development company focused on creating effective and environmentally sustainable methods for controlling parasites and pests, particularly parasitic nematodes. These roundworms are significant agricultural pests, inflicting billions of dollars in damage to various crops, such as soybeans, corn, cotton, strawberries, and bananas. Additionally, some nematodes are responsible for serious human diseases, including hookworm, whipworm, and roundworm infections, as well as filarial infections that lead to lymphatic filariasis and onchocerciasis. By developing innovative genes and molecules, Divergence aims to address the challenges posed by these harmful organisms in both agricultural and medical contexts.

Veran Medical Technologies, Inc. is a medical device company specializing in minimally invasive therapeutic devices for interventional oncology. Headquartered in St. Louis, Missouri, the company focuses on developing products that assist physicians in diagnosing diseases and delivering targeted therapies. Its offerings include the SPiNView thoracic navigation system, an electromagnetic device designed for the biopsy of solitary pulmonary nodules, and the ig4 IR System, which aids in performing biopsies and other procedures for the lungs, liver, and kidneys. Additionally, Veran Medical provides various instruments such as the vPad2 tracker device and the SPiNPerc hybrid diagnostic tool. The company's innovative solutions utilize advanced imaging technologies to create dynamic 3D maps of respiratory pathways, enhancing procedural planning and navigation, ultimately helping clinicians to expedite cancer diagnosis and treatment. Founded in 2003, Veran Medical Technologies is committed to improving patient outcomes through precision-guided interventions.

Asoyia, LLC is a company based in Iowa City, Iowa, specializing in the production of soybeans and soybean oil. Established in 2004, Asoyia serves a diverse clientele that includes food processors, institutional food management services, and restaurant chains. The company distributes its products through various distributors, ensuring a wide reach in the market. In addition to its headquarters in Iowa City, Asoyia operates locations in Des Moines and Cedar Rapids, Iowa, as well as Bloomington, Illinois.

CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that enable the integration of enzymes into traditional chemical absorption processes for effective CO2 removal. In addition to its primary focus on carbon capture, Akermin is also exploring applications of its stabilized enzyme technology in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The company aims to commercialize its technology, which originated from research at Saint Louis University, and has demonstrated its capabilities in developing sustainable solutions for a range of industries.

Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Singulex, Inc. is an immunodiagnostics company specializing in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company develops the Sgx Clarity System, an advanced in vitro diagnostics platform that detects low abundance biomarkers with high sensitivity, down to femtograms per milliliter. This system supports cardiovascular health management through services aimed at clinicians and personalized wellness programs for patients. Singulex offers ultra-sensitive immunoassay solutions and laboratory testing services that enhance patient care by facilitating proactive health management and aiding in the discovery of new therapeutics. The company serves a diverse clientele including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Singulex, originally established as BioProfile Corporation in 1997, rebranded in 2003 and is headquartered in Alameda, California, with an additional office in Basel, Switzerland.

Dreamerz Foods, Inc. provides various natural sleep products. It offers natural sleep beverage, a dietary supplement in the form of an all-natural, creamy, and dairy-based functional sleep beverage. The company also provides chocolate pillows, soothing dairy products, and herbal fruit-flavored mix. It offers its products through stores and online shops. Dreamerz Foods, Inc. was founded in 2006 and is based in San Francisco, California.

The Natural Dentist, Inc., founded in 1995 and based in Medford, Massachusetts, is a manufacturer of oral care products, including mouth rinses and toothpastes. Initially established as Woodstock Natural Products Inc., the company rebranded in 2005 to focus on natural and effective solutions for dental hygiene. The Natural Dentist provides its products through various channels, including retail stores, online platforms, and direct phone orders. In 2010, the company was acquired by Revive Personal Products Company, which expanded its reach within the consumer healthcare market. The Natural Dentist emphasizes the importance of quality oral care, catering to health-conscious consumers seeking natural alternatives.

Attune Foods, Inc. is a producer of organic snacks headquartered in San Francisco, California, with a focus on probiotic wellness products. Founded in 2006, the company offers a diverse range of wellness bars in multiple flavors, including dark chocolate, mint chocolate, blueberry vanilla, and chewy options such as chocolate peanut butter and mango peach. In addition to wellness bars, Attune Foods also provides granolas featuring chocolate or yogurt chips, muesli, cereals, and graham crackers. The company's mission is to support customers in their pursuit of healthy eating through customizable food options.

AirXpanders, Inc. was a medical device company headquartered in San Jose, California, specializing in the design, manufacture, sale, and distribution of innovative medical devices aimed at improving breast reconstruction outcomes. Founded in 2005, the company developed the AeroForm Tissue Expander System, a needle-free and patient-controlled device specifically designed for use in two-stage breast reconstruction following mastectomy. This system allowed patients to expand tissue in a controlled manner before the insertion of breast implants. Despite its advancements in medical technology, AirXpanders filed for Chapter 7 bankruptcy and ceased operations on September 25, 2019.

AirXpanders, Inc. was a medical device company headquartered in San Jose, California, specializing in the design, manufacture, sale, and distribution of innovative medical devices aimed at improving breast reconstruction outcomes. Founded in 2005, the company developed the AeroForm Tissue Expander System, a needle-free and patient-controlled device specifically designed for use in two-stage breast reconstruction following mastectomy. This system allowed patients to expand tissue in a controlled manner before the insertion of breast implants. Despite its advancements in medical technology, AirXpanders filed for Chapter 7 bankruptcy and ceased operations on September 25, 2019.

Dreamerz Foods, Inc. provides various natural sleep products. It offers natural sleep beverage, a dietary supplement in the form of an all-natural, creamy, and dairy-based functional sleep beverage. The company also provides chocolate pillows, soothing dairy products, and herbal fruit-flavored mix. It offers its products through stores and online shops. Dreamerz Foods, Inc. was founded in 2006 and is based in San Francisco, California.

The Natural Dentist, Inc., founded in 1995 and based in Medford, Massachusetts, is a manufacturer of oral care products, including mouth rinses and toothpastes. Initially established as Woodstock Natural Products Inc., the company rebranded in 2005 to focus on natural and effective solutions for dental hygiene. The Natural Dentist provides its products through various channels, including retail stores, online platforms, and direct phone orders. In 2010, the company was acquired by Revive Personal Products Company, which expanded its reach within the consumer healthcare market. The Natural Dentist emphasizes the importance of quality oral care, catering to health-conscious consumers seeking natural alternatives.

Travanti Pharma is a privately held company focused on the design, development, and marketing of innovative drug delivery platforms that enhance the safety, compliance, effectiveness, and ease of medication administration. The company specializes in advanced technologies, including a non-invasive electronic drug delivery system that employs controlled low-level electrical energy to transport drugs through the skin or other sites in the body safely. Additionally, Travanti Pharma offers a wearable electronic disposable drug delivery system, which is a portable and disposable solution for transdermal medication delivery. Through these cutting-edge technologies, Travanti Pharma aims to improve patient outcomes and streamline the medication delivery process.

Singulex, Inc. is an immunodiagnostics company specializing in single molecule counting (SMC) technology for clinical diagnostics and scientific research. The company develops the Sgx Clarity System, an advanced in vitro diagnostics platform that detects low abundance biomarkers with high sensitivity, down to femtograms per milliliter. This system supports cardiovascular health management through services aimed at clinicians and personalized wellness programs for patients. Singulex offers ultra-sensitive immunoassay solutions and laboratory testing services that enhance patient care by facilitating proactive health management and aiding in the discovery of new therapeutics. The company serves a diverse clientele including pharmaceutical research laboratories, clinical research organizations, and academic institutions globally. Singulex, originally established as BioProfile Corporation in 1997, rebranded in 2003 and is headquartered in Alameda, California, with an additional office in Basel, Switzerland.

EraGen Biosciences, Inc. is a biotechnology company based in Madison, Wisconsin, that specializes in developing, manufacturing, and marketing molecular reagent products and software for research and clinical testing markets. The company provides molecular diagnostic assays designed for the early detection and monitoring of cancer, genetic disorders, infectious diseases, and other genetic-based conditions. Its product offerings include molecular diagnostic tests, analyte specific reagents, in vitro diagnostic reagents, and research use only reagents. Additionally, EraGen Biosciences offers MultiCode-PLx and MultiCode-RTx Analysis Software, which enable users to create customized templates for assay layouts and conduct quantitative and qualitative analyses, respectively. The company primarily serves clinical laboratories and medical researchers, distributing its products across the United States and Canada. Founded in 1994 as Sulfonics, Inc., it adopted the name EraGen Biosciences, Inc. in 1999.

Akermin, Inc. is a biocatalyst development company based in St. Louis, Missouri, founded in 2003. The company specializes in innovative solutions for the removal of carbon dioxide (CO2) from industrial gas streams, utilizing biocatalysis and nanotechnology. Akermin has developed proprietary delivery systems that enable the integration of enzymes into traditional chemical absorption processes for effective CO2 removal. In addition to its primary focus on carbon capture, Akermin is also exploring applications of its stabilized enzyme technology in various sectors, including food processing, biofuels, chemicals, and pharmaceuticals. The company aims to commercialize its technology, which originated from research at Saint Louis University, and has demonstrated its capabilities in developing sustainable solutions for a range of industries.

Kereos, Inc. is a biopharmaceutical company based in St. Louis, Missouri, specializing in the development of nanoscale drug delivery technologies and molecular imaging agents aimed at the detection and treatment of cancer and cardiovascular diseases. Founded in 1999, Kereos focuses on targeted delivery systems that enhance the effectiveness of therapeutic compounds, including existing drugs and novel candidates, particularly those that are too toxic or fragile for conventional delivery methods. The company's product portfolio includes KER-1001 and KER-1002, both cancer therapeutics utilizing natural products with demonstrated anti-tumor efficacy, and KER-1003, which targets angiogenesis. Additionally, Kereos offers diagnostic applications, such as KER 0001, an imaging platform for detecting angiogenesis. The company is also engaged in developing partnerships with pharmaceutical and imaging firms to advance its molecular imaging systems and cardiovascular disease MRI agents, thereby broadening its impact in the healthcare sector.

Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

Brand New Brands is a groundbreaking new company that brings together the entrepreneurial spirit of a start-up and the resources of an established corporation to create new foods and beverages that promote health and wellness. Brand New Brands uses a portfolio-based incubator model to develop and market the highest potential new functional food business opportunities for the U.S. marketplace. Core to their approach is the commitment to create food and beverage products that are efficacious (by medical standards), honest and transparent in their claims, and satisfying to eat or drink. By vetting and assessing the potential of scores of new product concepts, they take the most promising opportunities and fuse them with talented, passionate and proven entrepreneurial teams who turn ideas into thriving new ventures. They focus their efforts and resources by innovating “category-creating” brand platforms that are capable of crossing over from niche markets to the mainstream in three to five years. They only pursue opportunities where they can claim distinct competitive advantages over large food companies through IP, brand creation or non-traditional distribution. Their strategy is to take the most promising new nutritional technologies and deliver them to the marketplace through great-tasting products with engaging “lifestyle” brands that educate and attract loyal customers and progressive retail partners. They take opportunities to market that are likely to scale quickly due to the convergence of scientific advances, consumer readiness and media attention.

Travanti Pharma is a privately held company focused on the design, development, and marketing of innovative drug delivery platforms that enhance the safety, compliance, effectiveness, and ease of medication administration. The company specializes in advanced technologies, including a non-invasive electronic drug delivery system that employs controlled low-level electrical energy to transport drugs through the skin or other sites in the body safely. Additionally, Travanti Pharma offers a wearable electronic disposable drug delivery system, which is a portable and disposable solution for transdermal medication delivery. Through these cutting-edge technologies, Travanti Pharma aims to improve patient outcomes and streamline the medication delivery process.

ZyStor Therapeutics, Inc. is a privately-held biotechnology company focused on developing enzyme replacement therapies for lysosomal storage diseases. The company specializes in creating innovative replacement technologies that enhance the delivery of therapeutics designed to substitute for missing lysosomal enzymes. These therapies aim to address the needs of patients suffering from genetic disorders characterized by lysosomal storage dysfunction.

Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

Efficas, Inc. is a health-science and technology company based in Boulder, Colorado, founded in 2003. The company specializes in the research, development, and commercialization of products designed for the nutritional management of the immune system in both humans and pets. Efficas offers EFFICAS CARE, a berry-flavored non-prescription medical food aimed at the dietary management of asthma and related allergies. The company's products are formulated to work with the body's natural systems, providing safe and effective relief from asthma and allergic conditions, thereby enhancing overall health benefits for its users.

Divergence is a research and development company focused on creating effective and environmentally sustainable methods for controlling parasites and pests, particularly parasitic nematodes. These roundworms are significant agricultural pests, inflicting billions of dollars in damage to various crops, such as soybeans, corn, cotton, strawberries, and bananas. Additionally, some nematodes are responsible for serious human diseases, including hookworm, whipworm, and roundworm infections, as well as filarial infections that lead to lymphatic filariasis and onchocerciasis. By developing innovative genes and molecules, Divergence aims to address the challenges posed by these harmful organisms in both agricultural and medical contexts.

Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Divergence is a research and development company focused on creating effective and environmentally sustainable methods for controlling parasites and pests, particularly parasitic nematodes. These roundworms are significant agricultural pests, inflicting billions of dollars in damage to various crops, such as soybeans, corn, cotton, strawberries, and bananas. Additionally, some nematodes are responsible for serious human diseases, including hookworm, whipworm, and roundworm infections, as well as filarial infections that lead to lymphatic filariasis and onchocerciasis. By developing innovative genes and molecules, Divergence aims to address the challenges posed by these harmful organisms in both agricultural and medical contexts.

Inoveon Corporation is a medical services company based in Oklahoma City, Oklahoma, that specializes in developing solutions for the detection, staging, and monitoring of eye diseases such as diabetic retinopathy, macular degeneration, and glaucoma. Founded in 1997, the company offers advanced technologies, including the iScan system, which is designed to detect and evaluate diabetic retinopathy and macular edema. Additionally, the INOVEON System works closely with physician groups to enhance compliance rates for diabetic retinopathy care. By providing innovative tools for eye health, Inoveon aims to improve patient outcomes and preserve eyesight. As of November 2010, Inoveon operates as a subsidiary of Ifa Systems AG.