Safar Partners

Safar Partners, established in 2019 and based in Cambridge, Massachusetts, is a venture capital firm that invests in seed to growth-stage technology companies. The firm focuses on platform technologies in cleantech and advanced materials, AI/IT and robotics, and life science/medical device sectors, primarily in the United States. Safar Partners is a Registered Investment Adviser (RIA) and manages venture capital funds, including Safar Partners Fund (2021 vintage) and Safar Partners Fund II.

Arda Kotikian

Associate

Parinaz Motamedy

Partner

Nader Motamedy

Founder and Managing Partner

Sahba Vaziri

Partner, CFO and Investment Committee Member

68 past transactions

Turing

Venture Round in 2025
Turing is a digital solutions provider that harnesses the power of AI to optimize asset performance across the entire water value chain.

QuEra Computing

Convertible Note in 2025
QuEra Computing is a company focused on developing quantum computing technology. They specialize in building large-scale quantum computers using neutral atoms. QuEra uses innovative techniques to manipulate and control qubits for quantum computation, aiming to solve complex problems in fields like chemistry, materials science, and machine learning. Their quantum computers operate on a platform that leverages arrays of neutral atoms that are highly scalable, providing a path toward achieving quantum advantage for practical applications.

Lightsynq

Series A in 2024
Lightsynq develops universal optical quantum interconnects that bridge the gap to large-scale quantum computers.

Circe

Seed Round in 2024
Circe specializes in the development of a scalable fermentation platform that transforms carbon dioxide, water, and electricity into organic molecules. By utilizing fermentation, the company aims to revolutionize food production by creating sustainable and healthy ingredients for plant-based foods. Circe focuses on using carbon dioxide as a feedstock, which allows for economically viable and climate-friendly production methods. Through careful selection of fats and fermentation-derived ingredients, Circe produces food items that appeal to consumers while significantly reducing the carbon footprint associated with traditional food manufacturing processes.

Ancilia Bio

Venture Round in 2024
Ancilia Biosciences focuses on developing engineered bacterial therapies aimed at treating diseases associated with the microbiome. The company specializes in creating virus-resistant live bacterial products that modulate the human microbiome, specifically targeting the viral components within the gut microbiome. By concentrating on healthy gut bacteria and their predatory phages, Ancilia engineers resistant bacterial strains to combat diseases. Its innovative approach includes the development of a new class of live biotherapeutics that allows medical professionals to target specific phages or viruses that induce lysis, with applications in immunology and oncology.

Tender Food

Series A in 2024
Tender Food is a food technology startup focused on developing plant-based and cultured meat products. Founded by researchers from Harvard University, the company utilizes novel fiber production technology to transform plant proteins into fibrous structures that closely replicate the texture and mouthfeel of traditional meat. This innovative method aims to create alternative meats that not only match the taste and nutritional value of animal meat but also promote vegan food options. Through its sustainable approach, Tender Food seeks to support meat companies and enhance the consumer experience with realistic and environmentally friendly alternatives.

Lucy Therapeutics

Venture Round in 2024
Lucy Therapeutics is a biotech company focused on developing innovative treatments for neurological diseases that originate from mitochondrial dysfunction. The company utilizes a unique approach to drug discovery by targeting early disease mechanisms, which holds potential for addressing a range of neurological disorders, including Parkinson's Disease and Alzheimer's Disease. In addition to its therapeutic efforts, Lucy Therapeutics is engaged in the development of proprietary small molecule therapies and diagnostic biomarkers aimed at enhancing the understanding and treatment of central nervous system conditions. By leveraging genetic technologies, the company aims to provide deeper insights into personalized medicine, thereby improving patient outcomes and enabling more precise healthcare interventions in the neurological field.

Active Surfaces

Pre Seed Round in 2024
Active Surfaces is commercializing MIT-developed ultra-thin-film solar technology. The company seeks to revolutionize the conventional energy sector by making solar power widespread and seamlessly integrating it into everyday materials. Its innovative manufacturing approach significantly reduces production expenses, presenting a transformational opportunity for semiconductor and electronics manufacturing.

Zanskar

Series B in 2024
Zanskar is a geothermal exploration and technology company focused on accelerating the discovery and development of geothermal energy resources. The company utilizes a predictive platform that leverages extensive data sets and advanced subsurface characterization technology. By integrating artificial intelligence and sophisticated sensing techniques, Zanskar enhances the exploration process, allowing clients to uncover previously unknown geothermal resources while minimizing associated risks. Through its innovative approach, Zanskar aims to contribute to the growth and sustainability of geothermal energy as a viable alternative energy source.

Verve Motion

Series B in 2023
Verve Motion specializes in the development of exo-suits aimed at assisting workers engaged in physically demanding tasks. The company utilizes a combination of robotics, apparel design, and movement science to create lightweight wearables crafted from textile materials. These exo-suits are designed to adapt to the movements of the wearer, providing necessary support and force during critical moments while remaining nonrestrictive at other times. By focusing on safety and comfort, Verve Motion enhances the capabilities of workers in various industries, promoting a more efficient and secure working environment.

Quaise

Series A in 2023
Quaise is an energy company based in Cambridge, Massachusetts, focused on developing innovative millimeter-wave drilling systems to access deep geothermal heat. Founded in 2018, the company aims to overcome geographic limitations that currently restrict the utilization of geothermal energy. By repurposing existing fossil-fuel industrial assets, Quaise's technology enables the drilling of geothermal wells directly at operational power plants, facilitating a smoother transition to cleaner energy sources. This approach allows mining companies to collectively generate terawatts of clean power, rivaling the output of fossil fuels while achieving zero carbon emissions.

MetOx Technologies

Series B in 2023
MetOx Technologies is a manufacturer of high-temperature superconducting (HTS) wire, utilizing YBCO to facilitate the efficient transmission of electricity. This technology allows for the transmission of large amounts of electricity with minimal cross-sectional area, eliminating electrical loss and heat generation during operation. MetOx employs a proprietary one-pass metal-organic chemical vapor deposition process for the production of buffer and superconductor layers, enhancing the quality and cost-effectiveness of its HTS wire. The applications of this advanced wire include upgrading transmission and distribution lines, supporting magnetic confinement fusion reactors, and developing next-generation MRI scanners, as well as use in wind turbines.

Liquid AI

Seed Round in 2023
Liquid AI is a technology company that develops artificial intelligence solutions for various applications. It focuses on creating tools for data analysis and decision-making processes. Liquid AI serves industries such as finance, healthcare, and logistics.

Cogito

Venture Round in 2023
Cogito is a technology company that specializes in enhancing the emotional intelligence of phone professionals through advanced artificial intelligence and machine learning. By leveraging behavioral science, Cogito's software analyzes various behavioral signals during conversations, offering real-time coaching to agents. This system not only guides agents in their interactions but also provides a continuous assessment of customer experience for each call. Through its innovative approach, Cogito enables enterprises to foster stronger relationships with their customers, improve sales outcomes, and enhance the overall quality of service provided.

Veo Robotics

Series B in 2023
Veo Robotics, Inc., founded in 2016 and based in Waltham, Massachusetts, specializes in developing robotics systems that enhance manufacturing processes. The company focuses on creating industrial automation products that allow high-performance robots to work collaboratively and safely alongside human workers. By integrating advanced computer vision, 3D sensing, and artificial intelligence, Veo Robotics' products aim to create more flexible, productive, and efficient manufacturing workcells. Their proprietary algorithms and distributed sensing technologies enable clients to improve productivity while reducing operating costs in both manufacturing and logistics environments.

Venti Technologies

Series A in 2023
Venti Technologies is an autonomous vehicle developer focused on creating advanced logistics systems for the transportation of goods and people. Founded in 2018 and headquartered in Suzhou, China, and Weston, Massachusetts, the company has developed a proprietary suite of autonomy technologies that leverage rigorous mathematical modeling and deep learning. These technologies aim to enhance the safety and speed of goods transportation while enabling significant vehicle and cost efficiencies. Venti's solutions are designed to automate complex logistics environments, including heavy traffic areas and logistics hubs, thereby strengthening supply chains and supporting the transition to zero carbon emissions. The company’s mission emphasizes delivering reliable transportation solutions that contribute to a greener planet and foster the creation of new, knowledge-based jobs.

Satelles

Funding Round in 2023
Satelles, Inc. is a satellite communication company that specializes in providing secure timing and location services through the Iridium constellation of low-earth-orbit satellites. The company offers solutions that enhance authentication and identity management, including location-specific signal-in-space technology. Its services encompass a range of global navigation satellite systems (GNSS), including precision real-time kinematic GPS, various augmentation systems, indoor GNSS signal reception, and the integration of GNSS with inertial navigation. Satelles also provides commercial offerings such as real-time ranging signal delivery, orbit and clock bias correction, and user equipment software for time and location measurements. The technology is designed to protect critical infrastructure from GPS and GNSS attacks, ensuring stability and reliability for applications in IoT, cybersecurity, asset tracking, and more. Founded in 2008 and based in Reston, Virginia, Satelles serves state and local government service providers and operates as a subsidiary of iKare Corporation.

Gradient

Series A in 2023
Gradient’s mission is to cool the world by transforming every home to be more comfortable and healthy for the people who inhabit it — without compromising the environment. Today, heating and cooling equipment emits more greenhouse gas emissions than the entire transportation sector, and expansion in the use of cooling is projected to double these emissions in the next 30 years. However, comfortable buildings are critical for health and productivity, especially among communities that are vulnerable to the effects of climate change. Gradient’s vision is a future where everyone has access to comfortable buildings that are fully decarbonized. Our launch product is a direct-to-consumer high-efficiency and low-carbon heat pump.

Membrion

Series B in 2023
Membrion, Inc., founded in 2016 and based in Seattle, Washington, specializes in the manufacturing and commercialization of advanced membranes that filter molecules, including ions, under a variety of conditions such as heat, acidity, and biological sensitivity. Originating as a spin-out from the University of Washington, Membrion has received funding from multiple organizations, including the National Science Foundation and private investors, which has facilitated the transition from research to commercial production. The company's innovative ion exchange membrane technology is designed for applications in flow batteries, water purification, fuel cells, and pharmaceuticals, offering clients membranes that feature a longer lifespan and reduced costs.

Syntis Bio

Venture Round in 2023
Syntis Bio is a late-stage preclinical company focused on developing a new class of oral therapies. By utilizing innovative formulations, the company's drugs are designed to target specific tissues, which enhances bioavailability and expands treatment options across a broader range of diseases.

Harmony Baby Nutrition

Seed Round in 2022
Harmony is a biotechnology startup that creates human breast milk protein-based infant nutrition designed to help human babies thrive. It is the world’s first dairy-free, allergen-free and environmentally friendly infant nutrition. Harmony Baby Nutrition was established in 2018 and is based in Boston, MA.

Axoft

Seed Round in 2022
Axoft is a company focused on developing advanced implantable electronics that enhance communication between the brain and machines. Its flagship technology consists of bioinspired implants made from ultra-flexible plastic mesh, which provides a softer alternative to traditional plastic and silicone implants. This innovative design allows for scalability and the integration of multiple sensors within a single implant, closely matching the brain's mechanical properties. Axoft's implants aim to improve clinical outcomes for patients suffering from neurodegenerative conditions, such as Parkinson's disease, thereby transforming individual health and overall human experience.

5x5 Technologies

Convertible Note in 2022
5x5 Technologies Inc. specializes in developing unmanned aircraft systems and advanced data analytics solutions for critical infrastructure owners. Founded in 2016 and based in St. Petersburg, Florida, the company provides a software-as-a-service platform that utilizes artificial intelligence and machine learning to create accurate digital twin models of complex structures. This technology enables clients to optimize performance, automate workflows, and reduce operational costs while uncovering new revenue opportunities through enhanced portfolio-wide analytics. Trusted by leading companies, systems integrators, and governmental agencies, 5x5 Technologies combines 3D analytics with innovative system integrations, positioning itself as a leader in the unmanned aerial vehicle and data analytics sectors. The firm has a global workforce with employees across North and Central America, Europe, and Asia, and is supported by various investors, including Softbank Corp. and several innovation-driven family offices.

Zanskar

Series A in 2022
Zanskar is a geothermal exploration and technology company focused on accelerating the discovery and development of geothermal energy resources. The company utilizes a predictive platform that leverages extensive data sets and advanced subsurface characterization technology. By integrating artificial intelligence and sophisticated sensing techniques, Zanskar enhances the exploration process, allowing clients to uncover previously unknown geothermal resources while minimizing associated risks. Through its innovative approach, Zanskar aims to contribute to the growth and sustainability of geothermal energy as a viable alternative energy source.

2Pi

Seed Round in 2022
2Pi is a platform technology for optical metasurfaces that offers a new class of optical components and systems with exceptional performance, ultra-compactness, light-weight, and novel functionality for use in consumer electronics, industrial automation, automotive, and other applications.

Finwave Semiconductor

Venture Round in 2022
Finwave Semiconductor specializes in the development of advanced gallium nitride (GaN) transistors and integrated circuits (ICs) tailored for 5G communications and power conversion applications. The company utilizes a unique 3DGaN technology, specifically its differentiated fin field-effect transistor (FinFET) design, to enhance the performance of high-volume applications such as radio frequency front end (RFFE) systems for mobile devices. This innovative approach allows Finwave to create semiconductor materials with distinct properties, contributing to advancements in electronics and energy management.

Quaise

Series A in 2022
Quaise is an energy company based in Cambridge, Massachusetts, focused on developing innovative millimeter-wave drilling systems to access deep geothermal heat. Founded in 2018, the company aims to overcome geographic limitations that currently restrict the utilization of geothermal energy. By repurposing existing fossil-fuel industrial assets, Quaise's technology enables the drilling of geothermal wells directly at operational power plants, facilitating a smoother transition to cleaner energy sources. This approach allows mining companies to collectively generate terawatts of clean power, rivaling the output of fossil fuels while achieving zero carbon emissions.

Foundation Alloy

Seed Round in 2022
Foundation Alloy specializes in the development of advanced materials, focusing on the design of innovative alloys tailored for additive manufacturing. The company aims to create metal parts that promote environmentally sustainable manufacturing practices while reducing overall acquisition costs. By integrating proprietary alloy design technology with advanced manufacturing techniques and automation, Foundation Alloy enhances the performance and production efficiency of industrial applications. This approach allows front-line engineers to optimize the manufacturing process compared to traditional materials and methods.

Seaspire Skincare

Seed Round in 2022
Seaspire Skincare specializes in the development and manufacturing of multifunctional colorants and active ingredients derived from oceanic biodiversity. The company focuses on creating innovative solutions to address chronic and cosmetic hair and skin conditions while aiming to replace harmful components in traditional sunscreens. One of its key products features the biomolecule Xanthochrome, which provides enhanced protection against a wider spectrum of ultraviolet radiation compared to existing physical and chemical filters. This technology is designed for preventative skincare, promoting a healthier approach that minimizes adverse effects on both human and marine health. Through its sustainable and less toxic formulations, Seaspire Skincare contributes to advancing the skincare industry towards safer and environmentally friendly practices.

Agility Robotics

Series B in 2022
Agility Robotics Inc. is a robotics development company founded in 2015 and based in Albany, Oregon. It specializes in designing and developing bipedal robots, notably Cassie, which is capable of walking and running. The company leverages its expertise in legged locomotion, rooted in extensive academic research, to create robots that serve as mobile sensor platforms and can operate in real-world environments. Agility Robotics aims to produce efficient, agile, and robust mobility solutions that can work alongside humans in various settings, such as offices, factories, and homes. Its technology enables clients to automate tasks in diverse terrains with minimal programming, addressing the practical needs of academic, corporate, and military sectors.

Concerto Biosciences

Venture Round in 2022
Concerto Biosciences specializes in rebuilding microbial communities to enhance human health and environmental sustainability. The company has developed an ultra-high-throughput platform capable of measuring millions of microbial interactions, enabling the mapping of complex inter-species networks that dictate community behavior. This innovation allows Concerto to create "ensembles," which are specific combinations of microbes that collaboratively promote the recovery of damaged microbial ecosystems. By focusing on these microbial ensembles, Concerto aims to address critical global issues across various sectors, including agriculture, healthcare, and industry. The company's pioneering work positions it as a leader in the development of microbial solutions, fundamentally changing how humanity interacts with microbial life.

GelMEDIX

Seed Round in 2022
Gelmedix is a company focused on developing innovative biomaterial platforms aimed at enhancing drug delivery for complex ophthalmic treatments. Its core offering is a light-activated gel patch that serves as a drug-eluting sealant, featuring properties such as tissue adhesion, tunable drug release, and biocompatibility. This technology allows healthcare providers to minimize the reliance on traditional eye drops, thereby improving patient convenience. Furthermore, Gelmedix's platform supports a range of therapeutic applications, including cell-based therapies for vision restoration and sustained intraocular release of small molecules and peptides. Through its photo crosslinked hydrogels, the company aims to advance ocular and regenerative therapies, emphasizing bio-adhesion and tissue regeneration.

RightHand Robotics

Series C in 2022
RightHand Robotics, Inc. specializes in the manufacturing of robotic order-picking systems designed to enhance supply chain logistics and order fulfillment across various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015, the company is headquartered in Cambridge, Massachusetts, with an additional office in Frankfurt, Germany. RightHand Robotics offers innovative solutions like the ReFlex SF, which features a 3D-printed palm equipped with advanced servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that aids in gentle object handling. Their technology enables robots to automatically grasp a wide range of items from bins and cases without the need for extensive data entry or parameter tuning, making their systems cost-effective and adaptable to changing business needs.

Tender Food

Seed Round in 2022
Tender Food is a food technology startup focused on developing plant-based and cultured meat products. Founded by researchers from Harvard University, the company utilizes novel fiber production technology to transform plant proteins into fibrous structures that closely replicate the texture and mouthfeel of traditional meat. This innovative method aims to create alternative meats that not only match the taste and nutritional value of animal meat but also promote vegan food options. Through its sustainable approach, Tender Food seeks to support meat companies and enhance the consumer experience with realistic and environmentally friendly alternatives.

Quaise

Series A in 2022
Quaise is an energy company based in Cambridge, Massachusetts, focused on developing innovative millimeter-wave drilling systems to access deep geothermal heat. Founded in 2018, the company aims to overcome geographic limitations that currently restrict the utilization of geothermal energy. By repurposing existing fossil-fuel industrial assets, Quaise's technology enables the drilling of geothermal wells directly at operational power plants, facilitating a smoother transition to cleaner energy sources. This approach allows mining companies to collectively generate terawatts of clean power, rivaling the output of fossil fuels while achieving zero carbon emissions.

MicroByre

Venture Round in 2022
MicroByre, Inc. is a biotechnology company based in Berkeley, California, founded in 2017. The company specializes in developing genetically tractable strains from non-model micro-species, focusing on the genetic engineering of bacteria for industrial applications. MicroByre has created a platform for bacterial domestication that utilizes an automated characterization pipeline to identify underutilized bacteria with favorable metabolic traits. These bacteria are capable of converting unrefined biomasses into commodity chemicals more efficiently than traditional fermentation processes. The company’s innovative approach involves minimal genetic modifications to enhance the bacteria's flexibility and yield, reduce the need for nutritional additives, and improve resistance to contamination and phage attacks. By bridging the gap between promising scientific advances and practical applications, MicroByre positions itself as a valuable partner for various industries, offering collaborative opportunities through service agreements or joint development projects.

Via Separations

Series B in 2021
Via Separations, Inc. is focused on developing innovative membrane-based products for industrial liquid separation in challenging environments. Founded in 2016 and based in Somerville, Massachusetts, the company aims to address the significant energy waste in the chemical separation process, which accounts for 12% of U.S. energy consumption. By employing its advanced membrane technology, Via Separations can reduce energy use by up to 90% and enhance product output. Their highly selective and robust membrane filters replace traditional heat-based separation methods, contributing to industrial decarbonization efforts. The company is currently conducting pilot trials in pulp and paper facilities, with the goal of eliminating 100 million metric tons of CO2 emissions by 2050. Originating from MIT's Department of Material Science & Engineering, Via Separations has successfully scaled its technology and demonstrated working prototypes at a commercial level.

Verve Motion

Series A in 2021
Verve Motion specializes in the development of exo-suits aimed at assisting workers engaged in physically demanding tasks. The company utilizes a combination of robotics, apparel design, and movement science to create lightweight wearables crafted from textile materials. These exo-suits are designed to adapt to the movements of the wearer, providing necessary support and force during critical moments while remaining nonrestrictive at other times. By focusing on safety and comfort, Verve Motion enhances the capabilities of workers in various industries, promoting a more efficient and secure working environment.

Ubiquitous Energy

Series B in 2021
Ubiquitous Energy, Inc. specializes in the development of transparent photovoltaics that aim to enhance energy efficiency in everyday products and surfaces. The company's ClearView Power technology allows windows and other surfaces to harness solar energy while remaining visually indistinguishable from standard glass. This innovative approach enables the generation of electricity from ultraviolet and near-infrared light, providing a sustainable power source for various devices, including wearables, tablets, and smart glass applications. Founded in 2011 and based in Redwood City, California, Ubiquitous Energy originated from research at MIT and has established a production facility in Silicon Valley. The company has also formed a strategic development agreement with Asahi Glass Co., Ltd., reinforcing its position as a leader in transparent solar technology.

Clerio Vision

Venture Round in 2021
Clerio Vision is a medical device company based in Rochester, New York, established in 2014. It focuses on developing innovative contact lenses that aim to address safety and performance challenges associated with traditional refractive surgery. The company utilizes laser-induced refractive index correction technology, which has the potential to transform the vision correction market by allowing physicians to effectively treat refractive index issues in the human cornea. Clerio Vision is actively engaged in the commercialization of its next-generation products, positioning itself as a key player in the ophthalmic medical device sector.

Swift Solar

Venture Round in 2020
Swift Solar Inc. is a company that designs and manufactures lightweight solar panels and systems, focusing on advanced solar technology. Established in 2017 and headquartered in San Carlos, California, with an additional site in Golden, Colorado, Swift Solar specializes in perovskite solar cells, which are engineered to be more efficient and cost-effective than conventional solar panels. The company’s innovative approach involves creating ultra-thin perovskite films that absorb various parts of the solar spectrum, resulting in high-efficiency tandem solar cells. These cells not only enhance solar conversion efficiency but also provide significant weight advantages, making them suitable for applications in aerospace, automotive, and building sectors. Swift Solar emphasizes domestic manufacturing and utilizes abundant raw materials to ensure scalability in its operations.

Concerto Biosciences

Seed Round in 2020
Concerto Biosciences specializes in rebuilding microbial communities to enhance human health and environmental sustainability. The company has developed an ultra-high-throughput platform capable of measuring millions of microbial interactions, enabling the mapping of complex inter-species networks that dictate community behavior. This innovation allows Concerto to create "ensembles," which are specific combinations of microbes that collaboratively promote the recovery of damaged microbial ecosystems. By focusing on these microbial ensembles, Concerto aims to address critical global issues across various sectors, including agriculture, healthcare, and industry. The company's pioneering work positions it as a leader in the development of microbial solutions, fundamentally changing how humanity interacts with microbial life.

Humanyze

Funding Round in 2020
Humanyze offers workplace solutions that enhance organizational performance through people analytics. The company provides a platform called Wyze, which allows administrators to configure necessary company information, access insights via dashboards, and benchmark against external data sources. This platform integrates with internal systems to generate insights across various teams and departments. Additionally, Humanyze utilizes wearable sensors and Bluetooth beacons to collect data, which can be used individually or aggregated for management purposes. Founded in 2010 and headquartered in Boston, Massachusetts, with operations in Amsterdam, Humanyze was originally known as Sociometric Solutions, Inc. The company leverages advanced technology from the MIT Media Lab to help organizations make informed human resource and workplace decisions that enhance both employee experience and overall business outcomes.

Tender Food

Seed Round in 2020
Tender Food is a food technology startup focused on developing plant-based and cultured meat products. Founded by researchers from Harvard University, the company utilizes novel fiber production technology to transform plant proteins into fibrous structures that closely replicate the texture and mouthfeel of traditional meat. This innovative method aims to create alternative meats that not only match the taste and nutritional value of animal meat but also promote vegan food options. Through its sustainable approach, Tender Food seeks to support meat companies and enhance the consumer experience with realistic and environmentally friendly alternatives.

Agility Robotics

Series B in 2020
Agility Robotics Inc. is a robotics development company founded in 2015 and based in Albany, Oregon. It specializes in designing and developing bipedal robots, notably Cassie, which is capable of walking and running. The company leverages its expertise in legged locomotion, rooted in extensive academic research, to create robots that serve as mobile sensor platforms and can operate in real-world environments. Agility Robotics aims to produce efficient, agile, and robust mobility solutions that can work alongside humans in various settings, such as offices, factories, and homes. Its technology enables clients to automate tasks in diverse terrains with minimal programming, addressing the practical needs of academic, corporate, and military sectors.

5x5 Technologies

Series B in 2020
5x5 Technologies Inc. specializes in developing unmanned aircraft systems and advanced data analytics solutions for critical infrastructure owners. Founded in 2016 and based in St. Petersburg, Florida, the company provides a software-as-a-service platform that utilizes artificial intelligence and machine learning to create accurate digital twin models of complex structures. This technology enables clients to optimize performance, automate workflows, and reduce operational costs while uncovering new revenue opportunities through enhanced portfolio-wide analytics. Trusted by leading companies, systems integrators, and governmental agencies, 5x5 Technologies combines 3D analytics with innovative system integrations, positioning itself as a leader in the unmanned aerial vehicle and data analytics sectors. The firm has a global workforce with employees across North and Central America, Europe, and Asia, and is supported by various investors, including Softbank Corp. and several innovation-driven family offices.

Radical Plastics

Seed Round in 2020
Radical Plastics, Inc., based in Winchester, Massachusetts, develops biodegradable plastic compounds designed to address plastic pollution. Incorporated in 2018, the company utilizes a proprietary, naturally occurring catalyst to blend with conventional plastics, making them fully biodegradable in the natural environment. Their innovative technology offers soil degradable compounds specifically for agricultural film, providing an economically viable solution for brands seeking drop-in replacements for traditional plastics. Through its commitment to sustainability, Radical Plastics aims to contribute to reducing plastic waste and promoting environmental health.

Cogito

Debt Financing in 2020
Cogito is a technology company that specializes in enhancing the emotional intelligence of phone professionals through advanced artificial intelligence and machine learning. By leveraging behavioral science, Cogito's software analyzes various behavioral signals during conversations, offering real-time coaching to agents. This system not only guides agents in their interactions but also provides a continuous assessment of customer experience for each call. Through its innovative approach, Cogito enables enterprises to foster stronger relationships with their customers, improve sales outcomes, and enhance the overall quality of service provided.

RightHand Robotics

Venture Round in 2020
RightHand Robotics, Inc. specializes in the manufacturing of robotic order-picking systems designed to enhance supply chain logistics and order fulfillment across various industries, including e-commerce, food handling, and flexible manufacturing. Founded in 2015, the company is headquartered in Cambridge, Massachusetts, with an additional office in Frankfurt, Germany. RightHand Robotics offers innovative solutions like the ReFlex SF, which features a 3D-printed palm equipped with advanced servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that aids in gentle object handling. Their technology enables robots to automatically grasp a wide range of items from bins and cases without the need for extensive data entry or parameter tuning, making their systems cost-effective and adaptable to changing business needs.

Quaise

Seed Round in 2020
Quaise is an energy company based in Cambridge, Massachusetts, focused on developing innovative millimeter-wave drilling systems to access deep geothermal heat. Founded in 2018, the company aims to overcome geographic limitations that currently restrict the utilization of geothermal energy. By repurposing existing fossil-fuel industrial assets, Quaise's technology enables the drilling of geothermal wells directly at operational power plants, facilitating a smoother transition to cleaner energy sources. This approach allows mining companies to collectively generate terawatts of clean power, rivaling the output of fossil fuels while achieving zero carbon emissions.

GelMEDIX

Convertible Note in 2020
Gelmedix is a company focused on developing innovative biomaterial platforms aimed at enhancing drug delivery for complex ophthalmic treatments. Its core offering is a light-activated gel patch that serves as a drug-eluting sealant, featuring properties such as tissue adhesion, tunable drug release, and biocompatibility. This technology allows healthcare providers to minimize the reliance on traditional eye drops, thereby improving patient convenience. Furthermore, Gelmedix's platform supports a range of therapeutic applications, including cell-based therapies for vision restoration and sustained intraocular release of small molecules and peptides. Through its photo crosslinked hydrogels, the company aims to advance ocular and regenerative therapies, emphasizing bio-adhesion and tissue regeneration.

Commonwealth Fusion Systems

Series A in 2020
Commonwealth Fusion Systems LLC is a research and development company focused on advancing fusion energy technology to provide an inexhaustible power source. Established in 2017 and based in Cambridge, Massachusetts, the company utilizes rare-earth barium copper oxide superconductor technology to create fusion energy systems. Commonwealth Fusion Systems was spun out of the Massachusetts Institute of Technology (MIT) and collaborates with MIT’s Plasma Science and Fusion Center to leverage decades of government-funded fusion research. By integrating established physics with innovative magnet technology, the company aims to accelerate the commercialization of fusion energy, positioning itself as a key player in the transition to clean and renewable energy sources while addressing climate change challenges.

Nelumbo

Series A in 2020
Nelumbo Inc. is a materials innovation company based in Menlo Park, California, focused on developing advanced structural materials for the heating and cooling industry. Founded in 2015, the company specializes in manufacturing thin superomniphobic coatings, such as Ice-Nein and Omniphobe. These coatings enhance the performance of cooling coils in refrigeration and air conditioning systems by reducing frost buildup and improving energy efficiency, thereby minimizing equipment downtime and corrosion. Nelumbo's technology aims to unlock significant market opportunities by contributing to reductions in carbon emissions and energy consumption globally.

Kebotix

Series A in 2020
Kebotix, Inc. is a company focused on revolutionizing the discovery and production of chemicals and materials through the integration of artificial intelligence, machine learning, and robotic automation. Established in 2017 and based in Cambridge, Massachusetts, Kebotix's platform significantly accelerates the research cycle, condensing it from years to months. This enables scientists to discover new materials and formulate products with specific desired properties more efficiently. The company's mission emphasizes enhancing public health and sustainability while promoting green chemistry solutions to eliminate hazardous substances. By providing access to its advanced digital research and development tools, Kebotix supports partners in materials innovation and development initiatives.

EagleDream Technologies

Venture Round in 2020
EagleDream Technologies is a veteran-owned IT consulting firm established in 2013, known for its extensive experience and strong relationships in the information technology sector. The company specializes in cloud computing solutions, offering a comprehensive range of services that include cloud adoption strategies, operational excellence, data modernization, disaster recovery, cloud hosting, application development, data analytics, and artificial intelligence. EagleDream Technologies aims to help businesses harness the potential of cloud-native technologies, focusing on delivering exceptional customer service as a core value. Their commitment to serving clients first ensures high-quality outcomes and innovative solutions to complex business challenges.

Honeoye Remedies

Seed Round in 2020
Honeoye Remedies specializes in all-natural skincare products designed for cosmetic use. The company focuses on creating formulations that are free from harsh chemicals, perfumes, and artificial dyes. Utilizing high-quality, laboratory-tested ingredients, Honeoye Remedies harnesses the antibiotic properties of honey and tea tree oil to develop products that promote wound healing and address various skin issues such as rashes, scrapes, and dry skin. By prioritizing safety and effectiveness, the brand offers consumers a reliable alternative for their skincare needs.

Aramis Biosciences

Seed Round in 2020
Aramis Biosciences is an ophthalmology biopharmaceutical company focused on developing disease-modifying therapies for ocular surface diseases, particularly dry eye conditions. The company's goal is to transform the standard of care in the treatment of these eye disorders by providing innovative therapies that address the underlying causes of the diseases. Through its research and development efforts, Aramis Biosciences aims to improve the quality of life for patients suffering from ocular surface diseases by offering effective treatment options.

Verve Motion

Seed Round in 2020
Verve Motion specializes in the development of exo-suits aimed at assisting workers engaged in physically demanding tasks. The company utilizes a combination of robotics, apparel design, and movement science to create lightweight wearables crafted from textile materials. These exo-suits are designed to adapt to the movements of the wearer, providing necessary support and force during critical moments while remaining nonrestrictive at other times. By focusing on safety and comfort, Verve Motion enhances the capabilities of workers in various industries, promoting a more efficient and secure working environment.

Health Care Originals

Venture Round in 2019
Health Care Originals Inc. is a company based in Rochester, New York, specializing in the development of innovative solutions for managing chronic respiratory diseases, particularly asthma. Founded in 2014, the company has designed a wearable device known as ADAMM, which is part of a comprehensive three-part system that includes a smartphone application and a web portal. This technology is aimed at identifying and monitoring precursor symptoms of asthma attacks, providing users with actionable insights for better management of their condition. Additionally, Health Care Originals offers services for clinical trials, direct-to-consumer applications, and telemedicine, enhancing the overall effectiveness of respiratory monitoring and management.

Clerio Vision

Series D in 2019
Clerio Vision is a medical device company based in Rochester, New York, established in 2014. It focuses on developing innovative contact lenses that aim to address safety and performance challenges associated with traditional refractive surgery. The company utilizes laser-induced refractive index correction technology, which has the potential to transform the vision correction market by allowing physicians to effectively treat refractive index issues in the human cornea. Clerio Vision is actively engaged in the commercialization of its next-generation products, positioning itself as a key player in the ophthalmic medical device sector.

Xibus Systems

Venture Round in 2019
Xibus Systems, Inc. is a biotechnology company based in Somerville, Massachusetts, specializing in the development of microbiological analytics and testing tools. The company focuses on creating solutions that detect pathogens, allergens, and spoilage organisms in consumable products. By integrating materials science, biotechnology, and optics, Xibus Systems aims to provide quantitative and array-based testing capabilities that are both efficient and cost-effective. Their innovative technology is designed for high throughput and rapid results, while also featuring a roadmap for compact and handheld hardware options. This unique combination of proprietary materials and biological agents positions Xibus Systems to effectively address the growing demands for food safety and quality assurance in the market.

C2Sense

Series A in 2019
C2Sense, Inc. specializes in developing chemiresistive gas sensors and miniaturized sensing technologies aimed at enhancing food quality and safety, particularly in the food and agriculture sectors. Founded in 2013 and based in Cambridge, Massachusetts, the company’s sensors detect gases like ethylene and biogenic amines at low concentrations, allowing stakeholders throughout the supply chain—from growers to consumers—to monitor the freshness of fruits, meats, and other perishable goods, ultimately reducing waste. C2Sense is also advancing its Halo Diagnostics product, a digitally connected immunoassay reader that offers near-PCR sensitivity and facilitates real-time test results through a cloud-based, HIPAA-compliant platform. This technology supports remote healthcare by enabling physicians to access patient test results instantly. Additionally, C2Sense has developed versatile sensing solutions that provide product quality information and counterfeit detection, using safe molecular additives that report on the status of goods throughout the distribution process, thereby enhancing security in various sectors, including pharmaceuticals and luxury goods.

Lucy Therapeutics

Venture Round in 2019
Lucy Therapeutics is a biotech company focused on developing innovative treatments for neurological diseases that originate from mitochondrial dysfunction. The company utilizes a unique approach to drug discovery by targeting early disease mechanisms, which holds potential for addressing a range of neurological disorders, including Parkinson's Disease and Alzheimer's Disease. In addition to its therapeutic efforts, Lucy Therapeutics is engaged in the development of proprietary small molecule therapies and diagnostic biomarkers aimed at enhancing the understanding and treatment of central nervous system conditions. By leveraging genetic technologies, the company aims to provide deeper insights into personalized medicine, thereby improving patient outcomes and enabling more precise healthcare interventions in the neurological field.

Gradiant Energy Services

Venture Round in 2019
Gradiant Energy Services, established in 2012, is an oilfield services company specializing in water treatment for the oil and gas industry. Based in Denver, Colorado, with a regional office in Midland, Texas, the company caters to clients in the Permian and Marcellus shale plays. Gradiant's services include bacteria treatment, reusable clean brine, evaporative disposal, freshwater and desalination, and brine collection. It serves exploration and production (E&P) operators, helping them manage and treat flowback and produced water in a safe, reliable, and environmentally conscious manner.

Swift Solar

Seed Round in 2018
Swift Solar Inc. is a company that designs and manufactures lightweight solar panels and systems, focusing on advanced solar technology. Established in 2017 and headquartered in San Carlos, California, with an additional site in Golden, Colorado, Swift Solar specializes in perovskite solar cells, which are engineered to be more efficient and cost-effective than conventional solar panels. The company’s innovative approach involves creating ultra-thin perovskite films that absorb various parts of the solar spectrum, resulting in high-efficiency tandem solar cells. These cells not only enhance solar conversion efficiency but also provide significant weight advantages, making them suitable for applications in aerospace, automotive, and building sectors. Swift Solar emphasizes domestic manufacturing and utilizes abundant raw materials to ensure scalability in its operations.

Kebotix

Seed Round in 2018
Kebotix, Inc. is a company focused on revolutionizing the discovery and production of chemicals and materials through the integration of artificial intelligence, machine learning, and robotic automation. Established in 2017 and based in Cambridge, Massachusetts, Kebotix's platform significantly accelerates the research cycle, condensing it from years to months. This enables scientists to discover new materials and formulate products with specific desired properties more efficiently. The company's mission emphasizes enhancing public health and sustainability while promoting green chemistry solutions to eliminate hazardous substances. By providing access to its advanced digital research and development tools, Kebotix supports partners in materials innovation and development initiatives.

Liquid X

Venture Round in 2018
Liquid X is a company specializing in the development of innovative metallic inks that enable the printing of functional components for various electronic devices. Their inks, which contain actual metal atoms rather than nanoparticles or metal flakes, offer superior properties such as high conductivity, thin and precise features, and excellent adhesion. This unique formulation allows for low-temperature processing and short production times, making it possible to use a wide range of substrates, including paper, gauze, and flexible plastics. Liquid X collaborates with manufacturers in the electronics industry to create applications such as sensors, heating elements, and smart textiles. The versatility of their inks supports various deposition methods, including inkjet, flexography, and gravure, positioning Liquid X as a key player in the emerging market for advanced electronic materials.

Finwave Semiconductor

Finwave Semiconductor specializes in the development of advanced gallium nitride (GaN) transistors and integrated circuits (ICs) tailored for 5G communications and power conversion applications. The company utilizes a unique 3DGaN technology, specifically its differentiated fin field-effect transistor (FinFET) design, to enhance the performance of high-volume applications such as radio frequency front end (RFFE) systems for mobile devices. This innovative approach allows Finwave to create semiconductor materials with distinct properties, contributing to advancements in electronics and energy management.
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