SeedFolio

HDAX Therapeutics is a biotechnology company focused on developing small molecule therapeutics for cardiovascular and neurological diseases, with an emphasis on HDAC6-driven pathologies such as neuropathies and cardiometabolic disorders. The company is building a precision therapeutics platform based on a two-site binding mechanism to selectively inhibit HDAC6, aiming to deliver safe, efficacious, and long-lasting treatments that enable researchers to pursue novel therapies with improved accuracy and therapeutic potential.

VIAN Therapeutics is an early-stage biotechnology company focused on transforming retinal disease treatment. Its lead product, a first-in-class non-invasive eyedrop, aims to replace invasive injections for conditions like age-related macular degeneration and diabetic macular edema.

Vasa Therapeutics is a preclinical-stage biopharmaceutical company based in Encinitas, CA. It focuses on discovering and developing therapies for treating vascular diseases such as heart failure, peripheral artery disease, and sarcopenia.

Eversun, headquartered in San Diego, specializes in innovative, portable utility equipment designed to replace traditional fuel-based power and lighting systems. Their flagship product, the eTower, is a versatile, rapidly deployable unit that combines solar power, energy storage, communications, and lighting. Standing up to 23 feet tall in under a minute, the eTower provides reliable power and connectivity for first responders, military units, disaster response teams, event organizers, and construction crews operating in off-grid locations. Setting Eversun apart is its commitment to sustainability; the eTower is primarily solar-powered, backed by lithium batteries, significantly reducing greenhouse gas emissions compared to diesel generators. The company offers customizable solutions, technical support, and digital lighting assessments to meet clients' specific needs, empowering remote site operations with efficient, portable, and eco-friendly technology.

InProTher Aps is a biotechnology company based in Copenhagen, Denmark, focusing on the development of innovative vaccine technologies and candidates within the field of immunotherapy. Established in 2011, the company is dedicated to creating the first adaptive immune therapy that targets immunosuppressive genes associated with ancient retroviruses. InProTher is also engaged in the development of products aimed at combating HIV, papilloma viruses, and various forms of cancer. Through its research and development efforts, InProTher seeks to advance treatment options in the evolving landscape of immunotherapy.

Founded in 2018, Trio Pharmaceuticals is a biopharmaceutical company based in San Diego, California. It specializes in developing innovative cancer therapeutics that directly inhibit tumor growth and selectively target immunosuppression within tumors, without relying on current immune checkpoint pathways.

Tiamat Sciences is a start-up focused on producing affordable, animal-free growth factors and biomolecules through innovative plant-based bioreactors. Utilizing proprietary technology, the company manufactures a diverse array of high-value proteins, including antigens and growth factors, achieving significant cost reductions—up to 10 times lower than traditional methods, with potential for further reductions at scale. This technology not only enhances production efficiency but also supports ecological sustainability by providing plant-based alternatives to animal-derived materials in the pharmaceutical industry. Tiamat's approach increases the safety and speed of production, positioning it as a strategic partner for scaling operations in burgeoning sectors such as cellular agriculture and gene therapy. The low capital investment required for facility setup makes Tiamat an attractive option in a market poised for substantial growth.

Duo Oncology specializes in developing nanoparticle technology designed to penetrate established tumors efficiently. Collaborating with renowned university scientists and medical oncologists, the company aims to accelerate product development through strategic partnerships with established research organizations.

Anvil Diagnostics is a biotechnology company focused on developing innovative diagnostic solutions. It specializes in creating a sensing technology that can rapidly and accurately detect a wide array of pathogens and genetic markers in blood samples, with the initial aim of identifying hundreds of such targets within a few hours. This technology, based on digital polymerase chain reaction (PCR), is designed to enable precision medicine, particularly for patients with sepsis, by providing timely and precise diagnostic information, thereby helping to resolve clinical ambiguity and improve patient outcomes.

RecoverX develops computational evidence and safe AI technologies to augment medical decision-making and advance new medical evidence.

GroGuru Inc. is a technology company based in La Jolla, California, specializing in smart irrigation solutions for agriculture. Founded in 2014, GroGuru provides software as a service that enables farmers to monitor and manage irrigation effectively. The company leverages an Internet of Things (IoT) sensor network to deliver precise measurements of soil moisture, salinity, and temperature. By utilizing advanced analytics, GroGuru offers real-time insights and recommendations that help farmers optimize water usage, improve crop yields, and make informed decisions regarding irrigation schedules and fertilizer application. The company's solutions aim to promote sustainable farming practices while reducing input costs and conserving vital water resources.

VerImmune, based in Baltimore, Maryland, is an Immuno-Oncology company focused on developing innovative cancer therapies through its proprietary technology known as Anti-tumor Immune Redirection Virus-inspired Particles (AIR-ViPs). This first-in-class approach aims to harness and redirect pre-existing immune memory from pathogenic infections or childhood vaccines towards tumors. By doing so, VerImmune seeks to offer a transformative treatment option for patients with various types of cancers, especially those facing treatment resistance or limited therapeutic choices. The company's goal is to provide a low-toxicity solution that delivers durable benefits across a broad spectrum of cancer types.

EarthGrid is pioneering a novel approach to tunneling, trenching, and excavation through its patented plasma tunnel-boring technology. This innovative method utilizes high-power plasma torches to vaporize and break down materials such as rock and clay, enabling significantly faster operations and substantial cost savings compared to conventional techniques. The company's network of tunnels aims to enhance infrastructure and connectivity within communities by facilitating the movement of clean renewable energy, extending broadband access to underserved areas, and providing essential services like clean water and efficient transportation for e-commerce. EarthGrid's comprehensive infrastructure solutions are designed to create interconnected and sustainable environments, fostering improved access and quality of life for communities.

Veckta is an innovative energy transition market platform that facilitates the development of distributed energy systems and microgrid projects. By integrating advanced energy system engineering tools with a comprehensive marketplace, Veckta enables businesses and communities to assess their current energy needs and customize solutions tailored to their specific requirements, such as cost, reliability, and emissions. The platform connects clients with vetted capital, construction, and equipment suppliers, ensuring access to the best partners for designing, financing, and building sustainable energy solutions. Through transparent pricing and worldwide support, Veckta empowers users to make informed decisions that contribute to both their operational goals and environmental sustainability.

Ordaos Bio is a biomedical research company based in Manhattan, New York, established in 2019. It focuses on revolutionizing drug discovery and development through the integration of artificial intelligence and biology. The company operates a human-enabled, machine-driven platform that facilitates the design of novel immunotherapies for oncology and chronic inflammatory diseases. By providing an AI-driven drug discovery pipeline, Ordaos Bio empowers researchers to develop treatments that are more effective and safer than conventional methods, thereby addressing significant challenges in medical research and enhancing therapeutic outcomes.

Founded in 2020, AmplifiDx specializes in developing molecular point-of-care devices. Their flagship product combines visual appeal with ease of use, low cost, and high performance to deliver rapid test results, initially focused on COVID-19 detection.

PreView Medical develops an AI-driven optical diagnostic tool that aids in the detection and diagnosis of prostate cancer. Utilizing spectroscopy, it classifies tissue as benign or suspicious in real-time during prostate biopsy, creating a 3D map to enhance early detection and guide focal therapy.

eGlint develops biosensing technology and devices designed to deliver rapid, multiplexed biomarker analysis. The company is advancing a miniature biosensing device that uses a small blood sample to derive data on multiple biomarkers, and a real-time proteomics platform that measures hundreds of biomarkers within minutes. Its multiplexed, quantitative, and scalable approach provides actionable medical insights for point-of-care and clinical settings, enabling healthcare providers and researchers to obtain diagnostic information quickly from a single test.

Basilard BioTech specializes in a proprietary platform that revolutionizes the burgeoning cell-based therapies market. Its technology enables efficient gene delivery through a mechanical approach, enhancing cell viability and transfection performance.

Amplo Biotechnology is a biotechnology company developing adeno-associated viral therapies aimed at curing defects in neuromuscular junctions, with an initial focus on congenital myasthenic syndromes. Its lead program, AAV-Dok7, originated with a research team from the Institute of Medical Science at the University of Tokyo and is designed to be delivered via intravascular injection to trigger molecular events that address paralysis, breathing, and swallowing difficulties caused by neuromuscular junction defects.

Labviva operates a digital marketplace connecting life science researchers with suppliers of reagents, chemicals, and lab equipment. It offers over 10 million products, simplifying procurement through real-time inventory tracking, AI-driven purchase automation, and forecasting.

Deep Blue Medical Advances is a medical device company focused on surgical solutions for soft tissue repair and hernia treatment. It develops and manufactures hernia mesh products, including the T-Line mesh and related anchor clips, designed to improve fixation strength and reduce mesh-related failure during implantation. Founded in 2015 and headquartered in Durham, North Carolina, with an additional office in San Francisco, California, the company aims to address high hernia occurrence and recurrence by offering surgeon-invented designs such as mesh with integral suture-like extensions and faster, stronger fixation. Through its innovative mesh and fixation devices, Deep Blue Medical Advances seeks to enhance surgical outcomes, expand options in hernia care, and contribute to improvements in patient experience and recovery in the global hernia device market.

Founded in 2019, Inspirit is a pioneering company specializing in immersive science education. It offers a comprehensive platform featuring virtual labs, simulations, and classroom management tools, designed to enhance STEM learning worldwide.

Allotrope Medical Inc. is a Houston-based medical device company that specializes in manufacturing surgical devices aimed at enhancing surgical procedures. The company's flagship product, StimSite, is an intuitive handheld device designed specifically to assist surgeons in quickly and accurately identifying ureters during operations. This device not only aids in ureter localization but also functions as a blunt dissection tool, streamlining the surgical process. By employing a simple single-button design, Allotrope Medical's device eliminates the need for additional pre and post-operative procedures, thereby improving efficiency in pelvic surgeries. Established in 2016, the company focuses on innovative solutions that enhance surgical accuracy and patient safety.

Maxwell Biomedical, Inc. is a medical device company focused on developing innovative solutions for the treatment of atrial fibrillation. Established in 2018 and located in Solana Beach, California, the company is pioneering a device designed to provide real-time, pain-free left atrial pacing to restore normal sinus rhythm in patients experiencing atrial fibrillation. This device continuously monitors for episodes of atrial fibrillation and employs a unique therapy called Spatial Resynchronization Therapy (SRT) to terminate these episodes without shock, thereby reducing the overall burden of the condition. Maxwell Biomedical's technology incorporates a fully integrated atrial fibrillation care system that facilitates remote patient management and telehealth capabilities, allowing healthcare providers to monitor and manage patients more effectively while potentially slowing or halting disease progression.

Ivy is a turn-key service powered by intelligent software providing equitable solar access to residents and predictable returns to owners.

PercAssist develops percutaneous balloon catheters designed to improve left ventricular function and promote myocardial recovery in patients with severe heart failure. Their battery-powered, non-blood contact extravascular device is procedurally simple and aims to reduce recovery time, decrease long-term complications and hospitalizations, thereby increasing survival and improving quality of life.

Tiamat Sciences is a start-up focused on producing affordable, animal-free growth factors and biomolecules through innovative plant-based bioreactors. Utilizing proprietary technology, the company manufactures a diverse array of high-value proteins, including antigens and growth factors, achieving significant cost reductions—up to 10 times lower than traditional methods, with potential for further reductions at scale. This technology not only enhances production efficiency but also supports ecological sustainability by providing plant-based alternatives to animal-derived materials in the pharmaceutical industry. Tiamat's approach increases the safety and speed of production, positioning it as a strategic partner for scaling operations in burgeoning sectors such as cellular agriculture and gene therapy. The low capital investment required for facility setup makes Tiamat an attractive option in a market poised for substantial growth.

Strategikon Pharma, Inc. is a technology company based in San Rafael, California, founded in 2016. It specializes in developing software solutions that streamline the outsourcing processes between sponsors and providers in the pharmaceutical industry. Its flagship product, Clinical Maestro, is a comprehensive software platform designed for the end-to-end management of clinical business operations, including planning, outsourcing, and budgeting for clinical trials. This innovative software replaces traditional, labor-intensive methods, often reliant on Excel, which are costly and inefficient. Clinical Maestro integrates workflows to enhance communication and data sharing between biopharmaceutical companies and their outsourcing partners. The platform facilitates clinical financial management, vendor performance metrics, and contract lifecycle management, while also offering consulting services for new clinical business operations. Case studies with leading pharmaceutical companies have shown that Clinical Maestro can lead to significant savings and improved accuracy in budgeting, demonstrating its effectiveness in transforming clinical trial management.

Abintus Bio is a preclinical stage company specializing in gene therapy research. Founded in 2020 and based in Encinitas, California, the company focuses on developing products that reprogram immune cells within their native environment to enhance patient access and outcomes.

Ready, Set, Food! is a California-based company founded in 2017 that specializes in manufacturing and selling food products designed for infants. The company's main goal is to help parents reduce the risk of their babies developing allergies to common foods such as peanuts, eggs, and milk. Ready, Set, Food! offers a gentle, daily system that simplifies the introduction of these allergenic foods into infants' diets, potentially lowering the risk of allergies by up to 80%. The products are available for purchase online, making them accessible to a wide range of consumers.

Optimize Health provides a digital platform for Remote Patient Monitoring (RPM), enabling healthcare providers to comply with new Medicare CPT codes while offering an intuitive user experience for patients and providers. Its system is designed to be profitable for physicians from the first month.

Everest Labs, founded in 2018 and based in Fremont, California, specializes in developing advanced robotics solutions for the waste management and scrap metal industries. The company's flagship product, Celer, employs artificial intelligence, machine learning, and computer vision to enhance the sorting and quality control processes at material recovery facilities. By integrating these technologies, Everest Labs aims to increase the quality of recyclables while minimizing reliance on human labor, thereby supporting revenue growth for waste management companies. The company is focused on fostering sustainability in the industry by encouraging the use of recycled materials in manufacturing and packaging. Ultimately, Everest Labs aspires to establish itself as a leading provider of AI and robotics solutions in complex environments like waste management.

Buzz Solutions develops an AI-powered analytics platform for energy infrastructure. The platform automates inspection workflows by ingesting visual data captured from drones, helicopters, and field personnel, and applies AI algorithms to detect faults and anomalies on power line assets. It delivers actionable insights, predictive analytics, and heat maps to guide maintenance decisions, enabling condition-based maintenance. Utilities can use the solution to improve inspection efficiency, reduce costs and safety risks, and ensure regulatory compliance in managing critical grid infrastructure. By identifying faults early, it supports proactive maintenance to minimize outages and climate-related risks to the grid. The company is based in Palo Alto, California.

Chronus Health develops a portable diagnostic device for delivering point-of-care lab results in minutes. Its device enables real-time diagnosis at the point-of-care, improving time to care and patient outcomes.

Tourmo is a technology company founded in 2014 and based in San Diego, California, that specializes in developing advanced software solutions for telematics data collection via smartphones. With a focus on automating manual processes, Tourmo utilizes artificial intelligence to simplify the complexities associated with transportation workforces, vehicles, and network fleets. The company's platform delivers contextualized business intelligence and real-time decision-making capabilities, enabling organizations to enhance their operational efficiency and support their critical networks of personnel, vehicles, customers, and partners. Tourmo holds two U.S. patents related to telematics and drive-data collection, positioning itself as a leader in providing innovative solutions for mobile phone manufacturers, carriers, and app development companies in the U.S. and Europe.

AccessParks specializes in providing high-speed outdoor Wi-Fi networks for parks and public spaces. It offers fully managed fiber optic-fed broadband access, supporting thousands of simultaneous devices, along with 24/7 network monitoring and optimization.

Particella is a biotechnology company that specializes in developing a proprietary oral lipid nanoparticle technology designed to deliver mRNA and other nucleic acids. This innovative approach aims to transform the administration of biological medicines by utilizing the intestinal tract to facilitate the secretion of proteins into the bloodstream. By enabling the oral delivery of protein biologics, Particella's technology seeks to address the limitations of current methods, ultimately allowing healthcare providers to prevent gastrointestinal diseases in patients more effectively. The company's advancements hold the potential to create a new category of medicines, enhancing the accessibility and efficacy of treatments.

Resynergi is a company dedicated to addressing the global challenge of waste plastics by developing innovative biorefining technology. It specializes in manufacturing modular, low-emission systems that convert traditionally non-recyclable plastics into environmentally friendly fuels and chemical products. Utilizing a microwave-based technology, Resynergi's systems efficiently transform unrecycled waste plastics into biodiesel and other low carbon-intensity fuels. These systems are designed to be easy to deploy, scalable, and highly cost-effective, making them an attractive solution for clients seeking sustainable alternatives in fuel production. Through its efforts, Resynergi aims to promote a circular economy and reduce the environmental impact of plastic waste.

Regenosine is a healthcare company that develops regenerative therapies for tissue regeneration, with a focus on cartilage repair and joint preservation. Its therapies leverage a purinergic system to regulate tissue homeostasis and restore adenosine levels, enabling the healing potential of adenosine to support tissue regeneration.