UNIIQ

AVIGI Therapeutics is spearheading a new era of drug design and development with rationally developed drugs that leverage human capabilities in advanced chemistry and biotech innovations.

GEHECO is a technology company specializing in the development of drilling tools tailored for renewable energy applications, specifically focusing on the efficient installation of water-heat pumps in existing residential structures. The company aims to facilitate the transition to carbon-neutral heating methods by addressing the challenge of well drilling, a critical step in the installation process. GEHECO's innovative designs prioritize in-home installation, reduced environmental impact, and enhanced accessibility, thereby overcoming traditional barriers to the adoption of sustainable heating solutions.

Bionomic is a biotechnology company focused on sustainable agriculture. It specializes in identifying and managing plant diseases using advanced biological therapies, aiming to enhance crop resilience and reduce environmental impact.

Passionfruit helps in collecting sustainability data, automate admin tasks, and share audit-ready sustainability responses.

Hypersoniq is a technology company specializing in electrochemical sensor solutions for the global liquid industry. It collects and analyzes data to provide clear insights into liquid quality, enabling clients to maintain compliance, reduce costs, and minimize environmental impact. The company's innovative sensor technology, using Electrical Impedance Spectroscopy (EIS), can detect a wide range of micro contaminants with a single device, facilitating improved process quality and enhanced transparency in operations.

XS Innovations specializes in the development of innovative vascular access devices for hemodialysis patients. Their flagship product is a device that manages blood flow during dialysis sessions, opening and closing the anastomosis between an artery and a vein. This technology aims to reduce complications and enhance the quality of life for patients with end-stage kidney disease.

IridescentBio specializes in a proprietary platform that uses physicochemical modeling to predict the biophysical properties of antibodies, aiding medical researchers in making informed decisions about drug candidates, thereby saving time and resources.

BlueGen.ai is a company focused on creating privacy-safe synthetic data, which mimics real data while ensuring individual privacy is maintained. By leveraging advanced artificial intelligence and machine learning technologies, BlueGen.ai's platform generates synthetic datasets that facilitate faster data-driven innovation. This approach allows software developers to access data that resembles real-world scenarios without the risks associated with handling actual personal information. The company's commitment to privacy and data integrity positions it as a valuable resource for organizations seeking to harness the power of data while adhering to privacy regulations.

Lobster Robotics specializes in developing lightweight, low-cost robots for visual surveying in offshore wind farms. Their technology enables quick, affordable site assessments, reducing surveying costs and supporting the development of offshore renewables.

ExCulture is a biotechnology research company dedicated to developing life-saving pharmaceuticals through natural fermentation processes. The firm aims to innovate production methods by eliminating the reliance on animal sources and utilizing readily available carbon sources. It specializes in creating an animal-free substitute for heparin, a critical anticoagulant used to prevent blood clotting. By employing a patented mixed culture fermentation bioprocess, ExCulture produces heparin-like compounds that can be used in pharmaceutical applications, advancing the field of biotechnology and enhancing patient care.

Councyl provides an AI technology that speeds up and improves decision-making. Until now this wasn’t straightforward, however, Council introduces a scientifically proven innovation that is not dependent on Big-Data and produces fully transparent results. This makes self-learning decision support possible for any organization, including yours.

Weco is committed to environmental protection and technological advancement. The firm, which specializes in wave energy, creates methods for generating electricity from ocean waves.

Ore Energy is a company focused on developing innovative energy storage solutions aimed at enhancing the reliability of renewable energy. Officially launched in 2023 and headquartered in Amsterdam, North Holland, Ore Energy specializes in creating a cost-effective, multi-day energy storage system. This technology is designed to facilitate the integration of renewable energy sources, allowing consumers to access clean energy whenever necessary. By promoting decarbonized electricity, Ore Energy aims to contribute to the establishment of a fully decarbonized electricity grid.

Pelagen is a biotechnology company focused on creating bio-fabricated natural materials. The company engineers the molecules that give animal materials their unique properties, producing high-quality alternatives without relying on animals. This approach allows Pelagen to cater to environmentally conscious consumers by providing products that are both sustainable and ethical, ensuring that their offerings have no negative impact on the environment or animal welfare.

Vortice focuses on using water to empower people to lead healthier and happier lives.

MEMSYS, a Dutch startup spun off from Delft University of Technology, specializes in developing vibration-based energy harvesting and power management technology. The company's innovative solutions convert mechanical energy from machine and asset vibrations into usable electrical power, enabling wireless sensing applications and self-powered devices, particularly in the industrial Internet of Things and railway sectors.

Arceon is focused on advancing industrial capabilities through the development of innovative materials and structures. The company specializes in advanced ceramic matrix composite (CMC) materials that can endure extreme temperature ranges, from cryogenic conditions to elevated heat. These materials exhibit near-zero thermal expansion, high specific strength, and exceptional corrosion resistance, making them significantly lighter than aluminum alloys. By providing tailored solutions that enhance performance and sustainability, Arceon contributes to long-term stability in demanding environments, particularly in space applications, while supporting broader sustainable development efforts on Earth.

Reefy is a reef engineering company focused on creating climate-resistant infrastructure that integrates engineering and biology. The company develops modular artificial reefs aimed at providing coastal protection, enhancing offshore infrastructure, and restoring marine ecosystems. Its innovative platform features stable structures designed to dissipate wave energy, thereby safeguarding coastlines while simultaneously offering complex habitats for marine life. This dual approach enables coastal and marine developers to meet environmental objectives and reduce costs within a single project. Through its solutions, Reefy addresses the pressing challenges of climate change and ecosystem degradation, contributing to more resilient coastal environments.

Villari specializes in wireless structural health monitoring technology, focusing on the detection of fatigue cracks. The company provides a platform that includes wireless crack monitoring sensor units designed for various applications, such as remote inspection, automated warning systems, and predictive maintenance. Their technology is particularly applicable to infrastructures like steel bridges, heavy lift cranes, and offshore structures. By utilizing Villari's solutions, clients can make informed, data-driven maintenance decisions, enhancing the safety and longevity of their assets.

Magneto developed technology, which offers heating without fossil fuels and cooling without refrigerants. It is based on our patented Magnetocaloric heat exchangers, which change temperature in magnetic field. They heat up when magnetized and cool down when magnet is removed. Our customers then develop magnetocaloric heat pump around them. The heat pump uses magnet, our heat exchangers and water to generate heat or cold in temperature span from -80 to +200*C. Our heat exchangers are protected with strong patent portfolio securing our leader position in the market.

DeNoize specializes in innovative smart window technology that converts glass facades into effective noise-canceling systems. The company provides an active noise cancellation kit, which consists of electronic sensors, actuators, and controllers that are seamlessly integrated within window frames. This system operates in real time to actively mitigate transmitted noise, allowing customers to enjoy quieter environments and significantly reduce noise pollution. By transforming standard glass into a sound-dampening solution, DeNoize addresses the growing demand for tranquility in urban settings.

EXIT071 specializes in developing technology that enhances intercellular communication through the analysis of exosomes. Utilizing patented microfluidic technology, the company focuses on creating methods for biological analysis that aim to improve the specificity of diagnostics. By enabling researchers to analyze extracellular vesicles, including exosomes, EXIT071 contributes to advancements in both therapeutics and diagnostics, particularly in the identification of novel biomarkers. This innovative approach supports clinical research efforts, showcasing the potential for more precise diagnostic tools in the medical field.

Imuno focuses on the development of a structure-based discovery engine aimed at identifying cancer-specific epitopes for innovative therapeutic applications. By visualizing the surface of cancer cells, the company identifies optimal targets and designs medicines that specifically recognize and eliminate these cells. This approach facilitates the development of patient-specific immunotherapies and enhances traditional in-vitro safety studies by providing crucial information and guidance for creating safe and effective treatments. Through its advanced discovery engine, Imuno aims to contribute to the advancement of cancer therapies, ultimately improving patient outcomes.

QuantWare is a leading provider of quantum hardware, specializing in scalable quantum processors designed to enhance computational capabilities. The company has developed the VIO QPU scaling technology, which serves as a platform for various qubit designs, facilitating the development of quantum computers with the potential to exceed one million qubits. QuantWare operates under the Quantum Open Architecture paradigm, supplying fully packaged quantum processing units (QPUs) and offering Foundry and Packaging Services to clients in 20 countries across four continents. Its innovative 3D-dimensional chip architecture enables customers to build connected and scalable quantum systems, aimed at addressing complex challenges in fields such as climate and life sciences.

DeNoize specializes in innovative smart window technology that converts glass facades into effective noise-canceling systems. The company provides an active noise cancellation kit, which consists of electronic sensors, actuators, and controllers that are seamlessly integrated within window frames. This system operates in real time to actively mitigate transmitted noise, allowing customers to enjoy quieter environments and significantly reduce noise pollution. By transforming standard glass into a sound-dampening solution, DeNoize addresses the growing demand for tranquility in urban settings.

BIMINI Biotech is a startup based in Leiden, The Netherlands, focused on developing innovative therapeutic strategies for oncology. Founded in 2019, the company specializes in researching and developing oncology medicines that target the growth hormone receptor (GHR) and its interaction with insulin-like growth factor 1 (IGF-1). By rendering the growth hormone receptor dysfunctional, BIMINI Biotech aims to decrease cellular sensitivity to growth hormone, similar to the effects observed in Laron syndrome. This approach has the potential to enhance cancer treatment and contribute to advancements in therapies for metabolic diseases and aging.

Kaminari Medical is focused on developing an innovative diagnostic medical device aimed at enhancing coronary revascularization procedures. The company's flagship product is a catheter that integrates intravascular ultrasound (IVUS) and photoacoustic (PA) imaging, referred to as intravascular photoacoustics (IVPA). This advanced catheter provides medical professionals with detailed information about plaque location and composition, allowing for more accurate stent placement and improved therapy guidance. By enabling the visualization of different types of plaques, Kaminari Medical's technology aims to reduce the risk of heart attacks and the need for reinterventions, ultimately improving patient outcomes in cardiovascular care.

Qblox is a Dutch scaleup focused on quantum technology, specializing in the development of control hardware for quantum computers. The company offers patented, modular control systems that integrate hardware and software solutions designed to enhance the management of qubits. By creating a distributed processor architecture, Qblox simplifies experimental setups while improving gate fidelities through advanced electronics that reduce noise and drift. This innovation enables scientists to minimize crosstalk, implement low-latency control flows, and optimize measurement efficiency, addressing significant scientific and engineering challenges in the evolution of quantum computing. Qblox aims to support the transition from prototype quantum computers to powerful computational systems, thereby contributing to the broader advancement of quantum technology.

BIOND Solutions B.V., founded in 2017 and based in Delft, the Netherlands, specializes in developing innovative hardware solutions for cell-based assays. The company focuses on creating customizable organ-on-chips (OOCs) that surpass the limitations of traditional in vitro assays, facilitating advanced biological studies. BIOND Solutions engineers microfluidic devices that provide optimal cell culture environments for OOCs and Lab-on-Chip applications. This technology enables biologists to simulate natural physiological conditions, thereby promoting personalized medicine by accommodating genetic variations across diverse populations. By nurturing, stimulating, and monitoring cells as they would exist in the human body, BIOND Solutions aims to enhance drug discovery and tailor treatments to individual needs.

Smart-Ship, founded by brothers Roy and Brent Kok, is a maritime technology company dedicated to enhancing safety, sustainability, and efficiency in maritime operations. The company has developed innovative force-feedback control levers that improve the interaction between ship operators and vessels, providing a more intuitive and responsive steering experience. This technology aims to reduce operator fatigue, particularly during extended journeys, and facilitates a smoother handling of complex maritime tasks. By integrating haptic feedback into ship controls, Smart-Ship is paving the way towards more autonomous shipping solutions, ultimately contributing to a more sustainable future for the maritime industry. The management team includes Jelle Tiemensma as CTO, who brings additional expertise to the company's mission.

Delta Diagnostics, founded in 2018 as a spin-off from TNO – The Netherlands Organisation for Applied Scientific Research, specializes in photonic biosensor technology. The company leverages patented innovations developed in TNO's Optics department to commercialize rapid, sensitive, and low-cost biosensors and instruments. These advanced biosensors utilize integrated photonics and optical chips containing waveguides that facilitate the transportation of light across multiple sensors. This technology enables real-time, label-free monitoring of biomarkers, allowing for accurate concentration measurements within minutes. Delta Diagnostics aims to enhance research in life sciences and facilitate the development of novel diagnostics through its innovative biosensing solutions.

TILER is a Dutch company founded in 2019, based in Delft, South Holland, that specializes in wireless charging solutions for light electric vehicles, particularly e-bikes. The company's innovative charging tile is installed on the ground and allows vehicles to charge effortlessly through their kickstands, eliminating the need for cumbersome cables and connectors. This user-friendly technology aims to support the sustainable growth of light electric vehicles by providing a reliable and intuitive charging infrastructure. By enabling seamless charging, TILER seeks to promote the adoption of e-bikes and improve the overall convenience for users.

Buddy Payment B.V. is a company based in Rotterdam, the Netherlands, that has developed an internet banking application known as Buddy. Founded in 2018, this application assists users in managing their finances by providing insights into their income and expenditures. It enables users to send inquiries regarding bills, surcharges, or benefits, thereby facilitating better understanding and control over their financial obligations. Additionally, Buddy offers advice on managing cash flow, helping users to set aside fixed costs and providing tips to save on purchases. Through these features, Buddy Payment aims to prevent debt and improve users' overall financial well-being.

ROCSYS is a company that specializes in developing solutions for fully automating electric vehicle (EV) charging sites. By utilizing proprietary soft robotics technology and computer vision, ROCSYS enables EV infrastructure operators to enhance asset utilization and streamline operations for fleet operators. The company's offerings not only support the efficient management of charging services but also prepare businesses for advancements in self-parking and autonomous driving technologies. ROCSYS provides a comprehensive suite of remote management tools and an API integration platform, addressing the increasing demands of the EV industry and promoting sustainable transportation solutions.

PATS Indoor Drone Solutions, founded in 2018 and based in Delft, the Netherlands, specializes in the design and development of small autonomous drones aimed at insect control. The company employs bioinspired technology to maintain the delicate balance of greenhouse ecosystems by selectively targeting and eliminating harmful insects. With a growing demand for sustainable agricultural practices and increasing regulations on traditional insecticides, PATS addresses these market needs by offering a more environmentally friendly alternative. Their innovative approach not only facilitates sustainable insect management but also helps horticulture farmers reduce costs associated with traditional insect control methods.

Addoptics specializes in the production of custom optical products, focusing on augmented reality (AR) glasses that blend seamlessly with individual style and prescription needs. The company addresses the significant challenge of making AR glasses appealing for mass adoption, moving away from the bulky designs often associated with technology. Utilizing patented lens link technology and advanced three-dimensional printing techniques, Addoptics offers flexible manufacturing services for prototyping and small-series production of personalized lenses. This innovative approach allows clients to obtain unique optics with integrated waveguide technology at competitive prices, making augmented reality more enjoyable and accessible for a broader audience.

Captain AI B.V. specializes in developing autonomous shipping solutions by leveraging high-fidelity simulation, advanced sensors, and deep learning techniques. Founded in 2018 and located in Rotterdam, the company focuses on creating software that enhances the efficiency of shipping systems. By utilizing a high-fidelity simulator, Captain AI enables rapid testing and validation of code, facilitating quick iterations that conserve emissions, fuel costs, and other resources. This innovative approach allows businesses requiring autonomous ships to implement autopilot systems more swiftly and cost-effectively.

Focus is a legal tech startup based in Rotterdam, Netherlands, founded in 2019. The company has developed an AI-powered platform that ranks patents according to their technological significance, utilizing a unique algorithm that integrates insights from the patent industry with econometric models. This innovative ranking system has shown effectiveness in several technical domains during testing with potential clients. Additionally, Focus's platform provides tools for rapid tech scouting, AI comparisons, and future forecasting, assisting businesses in identifying promising emerging technologies and making informed investment decisions.

SeraNovo is a pharmaceutical company that specializes in improving the bioavailability of water-insoluble medications. It offers a proprietary drug formulation platform that utilizes a novel class of liquids, which are neither aqueous nor lipid-based, to enhance the absorption of poorly soluble small molecules. This innovative approach leverages deep eutectic solvents to create solubility-enhancing formulations that are effective, well tolerated, and easily produced. By focusing on these advanced technologies, SeraNovo aims to reduce the development time for new medications, ultimately benefiting medical companies and improving patient outcomes.

Gearbox Innovations B.V., founded in 2016 and based in Maasdijk, the Netherlands, specializes in developing advanced technology solutions for various industries, including horticulture, manufacturing, and research. The company is known for its grading robot that utilizes vision technology and artificial intelligence to evaluate the quality of fruits and vegetables, allowing for comprehensive quality assessment. In addition to robotics, Gearbox Innovations focuses on creating smart products through innovative image analysis, efficient workstations, and tailored software solutions. The company collaborates closely with clients to transform ideas into prototypes, which are tested for usability and feasibility before being developed into final products. This approach enables customization and leverages the company's extensive knowledge in high-tech industries to enhance operational efficiency in supply and value chains.

Seranova is a developer and manufacturer of ceramic products.

Tetrahedron is a research and development company focused on creating innovative active ingredients aimed at maintaining or restoring health. The company specializes in developing natural, soluble compounds and original molecules derived from these compounds, catering to various sectors including cosmeceutical, nutritional, biomedical, and therapeutic applications. Through its work, Tetrahedron provides businesses with effective solutions that support health and wellness.

Tracefy specializes in providing Internet of Things (IoT) solutions focused on mobility and fleet management. The company has developed a software platform that offers global positioning system (GPS) tracking specifically designed for managing fleets of small electric vehicles, including bicycles and scooters. This software incorporates a GPS tracker that connects to various vehicles via the internet, allowing fleet managers and individual owners to access valuable data regarding vehicle locations, performance, and maintenance needs. By delivering these insights, Tracefy enhances the efficiency and oversight of fleet operations, catering to the growing demand for smart mobility solutions.

QLayers specializes in developing robotic coating technology that enhances the efficiency of coating applications across various industries. Their flagship product, the Slash100, is designed for the automated application of coatings, allowing for the coating of large surfaces in diverse environments and conditions. This technology focuses on creating functional sharkskin coatings that reduce drag on vehicles such as wind turbines and ships. By utilizing an autonomous painting robot that can scan surfaces and apply micro-structured coatings, QLayers significantly improves operational efficiency for coating companies, ultimately leading to reduced fuel consumption and enhanced performance.

MyLife Technologies B.V., founded in 2012 and based in Leiden, the Netherlands, specializes in the development and commercialization of nanoporous MicroNeedle Arrays (npMNAs) integrated into skin patches for drug delivery. The company is focused on creating innovative solutions for vaccine administration, particularly through its ceramic microneedle technology, which enables intradermal delivery of vaccines and drugs. This technology offers a more efficient alternative to traditional muscle injections, eliminating the need for cold chain logistics and providing a completely pain-free experience for patients. MyLife Technologies aims to respond swiftly to infectious disease outbreaks by collaborating with partners to develop intelligent skin patches that enhance patient treatment options.

Clockworks Data Innovation B.V., founded in 2017 and based in Rotterdam, the Netherlands, specializes in big data consultancy and custom data science solutions. The company focuses on developing predictive models and integrated software products to harness the power of big data. Its key applications include deepskye, which analyzes natural and built environments using satellite imagery, and a digitization solution that enables users to read water, gas, and electricity meters via their mobile phone's camera. Additionally, Clockworks provides predictive maintenance services that help users determine the remaining life of their assets, thereby optimizing maintenance efforts. By combining pattern recognition with human expertise, the company also offers process optimization solutions, enabling clients to derive actionable insights from their data.

Manometric specializes in the development of advanced orthoses and prosthetics, focusing on creating comfortable and aesthetically pleasing products. The company utilizes proprietary 3D scanning technology and automation software to enhance the design and manufacturing process of hand braces and other orthotic instruments. This innovative system allows medical professionals to efficiently design customized braces tailored to individual patient needs, ensuring high consistency and quality. By addressing the shortcomings of traditional orthotic solutions, Manometric aims to improve the overall experience for users while making these essential medical devices more accessible.

Lotsofwater is a developer based in Leiden, the Netherlands, specializing in offshore floating solar systems designed to generate clean and affordable energy. The company focuses on creating floating platforms that utilize renewable energy technology, capable of enduring challenging sea conditions for extended periods. These platforms are secured by a mooring system that maintains their position, ensuring stable connections to the energy grid. By providing innovative solutions for the government and energy sector, Lotsofwater enables exploration of new methods for energy generation, contributing to the transition toward sustainable energy sources.

Samotics is a Dutch technology company that specializes in an AI-powered condition monitoring platform aimed at enhancing the availability of industrial electric motors and rotating equipment. By utilizing data from sensors and operational systems, Samotics' solution offers predictive insights that help companies identify and address potential equipment failures before they occur. This proactive approach enables organizations to reduce unplanned downtime, lower operational costs, and minimize energy waste. The company serves a diverse range of global industrial clients, including notable names such as Anglian Water, ArcelorMittal, and Nobian, helping them optimize their operations and improve the efficiency of their critical equipment.

Numeric Biotech is a biotechnology company based in Rotterdam, the Netherlands, focused on developing innovative compounds that target cell senescence. The company aims to create a portfolio of first-in-class treatments for age-related diseases, including cancer, by addressing various mechanisms associated with these conditions. Its research is centered on therapies that selectively eliminate senescent cells, offering potential solutions for the prevention and treatment of age-related ailments.

LeydenJar Technologies B.V. is a Netherlands-based company founded in 2016 that focuses on enhancing lithium-ion battery performance through the development of pure silicon anodes. By replacing traditional graphite anodes with innovative nanoporous silicon, LeydenJar Technologies significantly increases energy density, achieving a 70% improvement over current standards. This advancement not only leads to batteries with higher energy density of 1350Wh/L but also reduces costs by 20% and lowers the carbon footprint by 85%. The company's commitment to greener, more efficient battery technology positions it as a key player in the energy storage market.

Concord Neonatal B.V., founded in 2017 and based in Leiden, the Netherlands, specializes in the development of innovative delivery tables designed for the care of preterm infants. The company’s flagship product, a resuscitation table, allows neonatologists to stabilize newborns while keeping the umbilical cord attached, which maximizes the transfer of blood from the placenta. This design enables caregivers to provide lifesaving interventions immediately after birth, ensuring that infants receive essential support until they can breathe independently. Concord Neonatal's focus is on enhancing neonatal care and improving outcomes for vulnerable newborns and their families.

IMSystems focuses on advancing gearbox technology with its innovative Archimedes Drive, which eliminates traditional gear teeth to overcome the traction drive paradox. This patented technology utilizes Flexroller mechanics, allowing for high torque delivery in a compact design, achieving ratios up to 10,000:1. The Archimedes Drive combines the reliability of planetary drives with the precision of friction transmission, enabling industrial robots to achieve consistent and reliable torque transfer without compromising asset durability. By offering a lighter, stronger, and more efficient alternative to conventional speed reducer technologies, IMSystems aims to revolutionize the robotics industry, enhancing production speeds and operational precision.

Amylon Therapeutics B.V. is a biotechnology company based in Leiden, the Netherlands, that specializes in developing therapies for central nervous system disorders and beta amyloid-related conditions. Founded in 2017, the company employs RNA Modulation Technology to create innovative treatments for rare genetic diseases, aiming to address significant unmet medical needs within the field. As a subsidiary of ProQR Therapeutics N.V., Amylon Therapeutics is committed to transforming the understanding and treatment of neurological disorders, striving to provide effective solutions for patients and their families affected by these challenging conditions. The company's vision encompasses the establishment of a sustainable drug development platform that prioritizes comprehensive care and ensures that no patient is left without potential treatment options.

Vibes Technology B.V., founded in 2015 and based in Delft, the Netherlands, specializes in developing analytics software tailored for the engineering industry. The company focuses on experimental modeling, substructuring, and transfer path analysis, aiming to empower engineers to conduct complex analyses accurately and efficiently. Vibes Technology's software applications are designed to be intuitive and user-friendly, significantly lowering the time and expertise needed for effective sound and vibration analysis. One of their notable tools integrates with Matlab, allowing engineers to build high-quality dynamic models from measurements. This software combines experimental structures with numerical models, utilizes CAD data for 3D measurement preparation, and automates the transformation of measurements into FEM-compatible models, thereby facilitating early-stage resolution of noise and vibration challenges in product development.

Hercules Pharmaceuticals B.V., founded in 2013 and based in Leiden, the Netherlands, is a biopharmaceutical company focused on developing innovative oral non-toxic drug therapies for the chronic treatment of Triple Negative Breast Cancer and other solid tumors. The company's research centers on a novel treatment that inhibits the Aryl Hydrocarbon Receptor, which has shown potential in enhancing immune response to cancer, reducing cancer stem cell populations, and decreasing metastatic behavior. By targeting this receptor, Hercules aims to make cancer cells more sensitive to standard chemotherapy while also minimizing aggression in existing tumors. The company is in the process of preparing its anti-cancer products for clinical trials, demonstrating a commitment to advancing cancer treatment options. Hercules operates as a subsidiary of 22nd Century Group, Inc.

Sensius B.V., founded in 2015 and based in Rotterdam, Netherlands, specializes in developing advanced thermotherapy systems for treating head and neck cancers. The company's proprietary technology incorporates localized heating through an integrated microwave system, complemented by interactive software, which allows healthcare professionals to enhance traditional cancer treatments such as radiotherapy and chemotherapy. This innovative approach aims to improve patient outcomes and quality of life by mitigating the toxic effects commonly associated with standard therapies. Sensius has successfully treated seventy patients with its device, achieving a complete response rate of 81.8% at 12 weeks post-treatment. Currently, the company is working towards obtaining CE marking for its device, with significant interest from potential buyers, as it also plans to expand its application to other cancer types in the future.

Condi Food B.V. specializes in developing advanced hyperspectral imaging solutions to assess food quality. Founded in 2014 and based in Warmond, The Netherlands, the company employs its proprietary hyperspectral imaging technology to evaluate the quality characteristics of food products in a continuous and non-destructive manner. This innovative approach enables food producers to inspect items without physical contact or invasive methods, improving upon traditional labor-intensive processes that rely on visual inspections and manual sorting. By providing an automated solution for monitoring quality across the food supply chain, Condi Food aims to enhance efficiency and accuracy in food production, ensuring that defects and foreign materials are detected effectively.

Mayht is a company focused on innovating loudspeaker technology to create more compact, powerful, and cost-effective audio devices. By developing advanced loudspeaker transducers, Mayht enables the production of speakers that utilize smaller enclosures without sacrificing sound quality. This technology allows for the integration of powerful drivers into compact designs, making it possible to produce products like pocket-sized Bluetooth speakers that deliver an impressive audio experience. As a result, audio companies can enhance their offerings with high-performance speaker components that provide full-range sound at an affordable price.

Longbloom specializes in the preservation of fresh flowers, enabling them to last for six months or more through a patented processing technique that is significantly cleaner than traditional methods. The company focuses on fragile varieties such as orchids, gerberas, peonies, and roses, utilizing high-quality flowers sourced from the Netherlands, a region renowned for its flower cultivation. In addition to preserving flowers, Longbloom offers a subscription service that allows businesses and florists to rent bouquets composed of these stabilized flowers. This innovative approach not only extends the lifespan of cut flowers but also promotes sustainability by reusing residual materials from the preservation process.

AeroVinci is a company based in Delft, the Netherlands, focused on the development of innovative DroneDock technology. This self-sustaining drone docking station enables drones to autonomously land, recharge, process data, and transmit actionable information without human intervention. As a spin-off from TU Delft, AeroVinci aims to meet the increasing demand for fully autonomous drone operations, which are essential for scalability in various markets. The technology integrates seamlessly with major data collection platforms, allowing clients to gather extensive data efficiently and cost-effectively. By facilitating fully autonomous drone operations, AeroVinci is positioned to transform the landscape of drone usage across industries.

Hardt Hyperloop is focused on creating a transport system that enables emission-free travel over long distances, making it accessible to a broad audience. Evolving from a winning team at the SpaceX Hyperloop Competition, the company aims to develop a hyperloop system that can accommodate large volumes of passengers and freight. This innovative transport solution promises to offer on-demand, zero-emission travel that is both affordable and sustainable. By facilitating rapid connections between network cities, Hardt Hyperloop ensures minimal waiting times for travelers, enhancing the overall efficiency of urban mobility.

Red Tulip Systems BV is a provider of virtual mobile devices (VMD) that specializes in secure communications and identity management for government and corporate clients. Founded in 2015 and based in The Hague, the Netherlands, the company offers a product called WorkFone, which enables users to communicate without the need for multiple physical phones. This service allows mobile communications, applications, and data to operate within the security parameters of an organization, ensuring that no sensitive information remains on physical devices. The virtual devices are hosted in the cloud, delivered through a lightweight app, and feature real mobile numbers with voice and SMS capabilities. As a result, professionals such as security service officers and journalists can communicate securely without risking their identity. Red Tulip Systems is dedicated to providing solutions that meet the fiduciary responsibilities of its clients while facilitating lawful undercover operations.

Fibriant is a biotechnology startup dedicated to the development and production of recombinant fibrinogen, a critical protein in blood that facilitates clotting and supports tissue repair and immune responses. The company operates a platform that produces flexible and biodegradable fibrinogen variants, which are designed to enhance processes such as wound healing and tissue remodeling. Fibriant's products aim to assist healthcare organizations in preventing complications, such as early and late-stage vein graft failure following bypass surgery, thereby improving patient outcomes in various medical applications.

Samotics is a Dutch technology company that specializes in an AI-powered condition monitoring platform aimed at enhancing the availability of industrial electric motors and rotating equipment. By utilizing data from sensors and operational systems, Samotics' solution offers predictive insights that help companies identify and address potential equipment failures before they occur. This proactive approach enables organizations to reduce unplanned downtime, lower operational costs, and minimize energy waste. The company serves a diverse range of global industrial clients, including notable names such as Anglian Water, ArcelorMittal, and Nobian, helping them optimize their operations and improve the efficiency of their critical equipment.

Andrupos is a web-based automated document examination system focused on detecting document fraud in various forms, including banknotes, ID cards, and financial documents. The software leverages validated research and pilot studies to provide reliable authentication of printing techniques and sources, enabling quick and confident fraud detection reports. A notable feature of Andrupos is its ability to trace counterfeits back to specific printers, assisting law enforcement in identifying organized criminal groups involved in forgery. The system conducts non-destructive analysis of printed documents, identifying the printing technology used, as well as details such as printer brand and model, which are critical in combating document-related crimes. Its innovative approach offers banks and passport offices a powerful tool for early fraud detection and prevention.

VarmX is a pharmaceutical spin-off from the Leiden University Medical Center focused on developing and manufacturing therapeutic proteins aimed at restoring blood clotting in patients experiencing severe bleeding. The company's lead product, PseudoXa, is a modified recombinant human coagulation factor X designed to work effectively in the presence of direct factor Xa anticoagulants like rivaroxaban, apixaban, and edoxaban. These anticoagulants are widely used for preventing and treating thrombosis and stroke but can lead to dangerous bleeding as a side effect. PseudoXa addresses this critical issue by providing a means to stop and prevent bleeding, thereby enhancing the safety of anticoagulant therapies for millions of patients worldwide.

SenseGlove specializes in developing digital glove technology that enhances interaction in virtual and augmented reality environments. The company's flagship product integrates haptic feedback, allowing users to feel, touch, and interact with virtual objects as if they were real. This technology serves as a development tool for various applications, including virtual reality training, virtual prototyping, research, telerobotics, and marketing. By enabling natural interactions akin to those in the physical world, SenseGlove aims to unlock the full potential of VR and AR, facilitating an immersive experience that bridges the gap between digital and real-world interactions.

Wolk is a company focused on enhancing safety for seniors and rehabilitation patients through the development of an innovative wearable hip airbag. This technology is designed to prevent hip fractures by cushioning the impact during falls, thereby promoting mobility and confidence among users. By addressing the concerns of elderly individuals who fear falling, Wolk aims to improve their quality of life and enable them to move freely without the constant worry of injury. The company's commitment to safety and rehabilitation highlights its role in supporting vulnerable populations in maintaining their independence.

Spatialise is a technology company that specializes in soil health monitoring. It develops software that uses satellite data and artificial intelligence to estimate soil nutrients and provide insights on regenerative agriculture. This enables farmers to track and improve the health of their soil, promoting biodiversity and water conservation, while also offering cost-effective and scalable measurement, reporting, and verification (MRV) solutions.

XS Innovations specializes in the development of innovative vascular access devices for hemodialysis patients. Their flagship product is a device that manages blood flow during dialysis sessions, opening and closing the anastomosis between an artery and a vein. This technology aims to reduce complications and enhance the quality of life for patients with end-stage kidney disease.

GEHECO is a technology company specializing in the development of drilling tools tailored for renewable energy applications, specifically focusing on the efficient installation of water-heat pumps in existing residential structures. The company aims to facilitate the transition to carbon-neutral heating methods by addressing the challenge of well drilling, a critical step in the installation process. GEHECO's innovative designs prioritize in-home installation, reduced environmental impact, and enhanced accessibility, thereby overcoming traditional barriers to the adoption of sustainable heating solutions.