Wireframe Ventures

Dev-first, fully-extensible managed Postgres.

Tyba provides end-to-end modeling of standalone and hybrid storage projects from early-stage development through operations, giving your business the edge to build and operate the best projects faster and more profitably.

Eating disorders affect people of all backgrounds, identities, and experiences, yet up to 90% won't get care. Arise aims to change that, breaking down barriers and stigma and expanding access to inclusive care through virtual treatment pathways, community, and ongoing support.

Synop develops a smart charging platform for commercial EV fleets. Synop accelerates the transition to electric commercial fleets through software that connects vehicles, chargers, and the grid. Synop also offers tools for EV fleet management, charge management, energy management, and billing and payments.

Endpoint Health is a precision immunology company that is breaking the efficacy barrier of traditional pharma's “one-size-fits-all” drug development strategy by developing precision therapies with outsized efficacy potential in autoimmune and inflammatory conditions. They’re accomplishing this by leveraging OMNAI, their proprietary AI-powered patient discovery platform, to identify and match high-potential therapies to the patients most likely to respond.

Salient creates a weather intelligence platform that combines novel ocean and land-surface data with machine learning and climate expertise to provide accurate subseasonal-to-seasonal (S2S) weather forecasts 2 to 52 weeks ahead. Salient's tools sift through large datasets to identify complex climate system relationships in order to provide accurate forecasts used in agriculture, energy, finance, supply chain, and other industries. Salient utilizes scientific knowledge to assist individuals and organizations in better understanding and preparing for the increasing volatility of climate change.

We provide car dealers and private party buyers with vehicle reports for used electric cars. Understanding the battery health and typical ranges of electric cars as they age is more complicated. And it's more important than knowing the odometer reading.

We are a vehicle technology company optimistic about the future; our work has always reflected that, and now our name does too. Terraline represents the benefits of rapidly revolutionizing and decarbonizing freight transportation, a significant contributor to global greenhouse gas emissions. With Terraline’s clean-sheet, battery-electric heavy truck designed to eliminate CO2 emissions, we are fully committed to benefiting the planet by disrupting a massive segment of the transportation industry.

Phytoform Labs is a biotechnology company which aims to help breeders to cut down plant breeding times from decades to years using new gene editing technologies. Predictably evolving plants will maximise yields for breeders and improve the economics of breeding for customers.

Near Space Labs is an aerial imagery and earth observation company, Near Space Labs' imagery makes it easy to monitor assets and gain remote access over broad or specific areas. Near Space Labs offers cloud-based delivery of fully processed images through its API. The company provides frictionless, affordable imaging for insurance, utilities, infrastructure, conservation, smart cities, retail, energy, government, and disaster response.

LevelTen Energy is a company that provides renewable transaction infrastructure. It connects renewable energy buyers, advisors, and sellers and gives them the tools and services they need to get better deals done faster. Its technology-enabled marketplace connects a broader class of C & I to utility-scale projects.

Enveda is a biotechnology company that utilizes AI-powered tools to explore and characterize molecules from living organisms. By developing a comprehensive database of chemical biodiversity, Enveda aims to accelerate the discovery of new medicines.

Gridware exists to enhance and protect the mother of all networks: the electrical grid. The grid touches everything grinds to a halt, and the consequences can be dire: wildfires burn, land is destroyed, property is damaged, progress stops, and lives are lost. Our team engineers an advanced sensing system to continuously analyze both the electrical and mechanical behavior of grid assets. Utilizing high precision sensor arrays, the system identifies and allows preemptive mitigation of faults. Our technology has been proven with utilities to bolster safety, reliability, and reduce customer outage durations. The demand for power will only increase. We protect the grid of today while we build the grid of tomorrow. Gridware is privately held and backed by the best climate-tech and Silicon Valley investors. We are headquartered in the Bay Area in northern California.

Scenery is a collaborative video editor on the web for teams creating videos together. The company was founded in 2020 by the team behind Jumpcut and SnappyTV.

We provide car dealers and private party buyers with vehicle reports for used electric cars. Understanding the battery health and typical ranges of electric cars as they age is more complicated. And it's more important than knowing the odometer reading.

MycoWorks is a biotech company that provides non-plastic and non-animal materials to the market. Their mycelium products provide natural alternatives to plastic foams, textiles, and leather. Their products are made from bio-materials using fungal mycelium to create energy-efficient and biodegradable alternatives to plastic foams, synthetic textiles, engineered woods, and leather for use in aerospace, automobiles, apparel, and architectural interiors.

Enveda is a biotechnology company that utilizes AI-powered tools to explore and characterize molecules from living organisms. By developing a comprehensive database of chemical biodiversity, Enveda aims to accelerate the discovery of new medicines.

Endpoint Health is a precision immunology company that is breaking the efficacy barrier of traditional pharma's “one-size-fits-all” drug development strategy by developing precision therapies with outsized efficacy potential in autoimmune and inflammatory conditions. They’re accomplishing this by leveraging OMNAI, their proprietary AI-powered patient discovery platform, to identify and match high-potential therapies to the patients most likely to respond.

Span.IO develops products to enable the rapid adoption of renewable energy and deliver an intuitive interface for the home. They are a group of engineers with a passion for building products that can deliver a positive impact on the environment while enhancing the consumer experience. They believe that developing intelligent hardware and software that provides visibility and control at the edge of the grid will be transformational to the energy sector. The company is backed by domain experts in energy, software, hardware, and consumer finance. They leverage their teams' collective experience in power generation, energy conversion, controls, and system integration to develop core products focused on enabling the rapid adoption of renewable energy.

MycoWorks is a biotech company that provides non-plastic and non-animal materials to the market. Their mycelium products provide natural alternatives to plastic foams, textiles, and leather. Their products are made from bio-materials using fungal mycelium to create energy-efficient and biodegradable alternatives to plastic foams, synthetic textiles, engineered woods, and leather for use in aerospace, automobiles, apparel, and architectural interiors.

Electriphi develops end-to-end energy management and fleet operations software for light, medium, and heavy-duty commercial fleets. It helps to ave energy costs, optimize infrastructure, and ensure fleet's operational readiness with Electriphi's managed charging software built on AI and machine learning technology.

For data teams looking to increase the availability of trusted data, Astronomer provides Astro, a modern data orchestration platform, powered by Apache Airflow, that enables the entire data team to build, run, and observe data pipelines-as-code. Astronomer is a commercial developer of Airflow, the de facto standard for expressing data flows as code, used by hundreds of thousands of teams across the world.

MODit provides smart, automated quality control for manufacturing. MODit's mass-deployable 3D scanning systems and cloud platform increase yields and streamline quality communication across the supply chain.

LevelTen Energy is a company that provides renewable transaction infrastructure. It connects renewable energy buyers, advisors, and sellers and gives them the tools and services they need to get better deals done faster. Its technology-enabled marketplace connects a broader class of C & I to utility-scale projects.

Span.IO develops products to enable the rapid adoption of renewable energy and deliver an intuitive interface for the home. They are a group of engineers with a passion for building products that can deliver a positive impact on the environment while enhancing the consumer experience. They believe that developing intelligent hardware and software that provides visibility and control at the edge of the grid will be transformational to the energy sector. The company is backed by domain experts in energy, software, hardware, and consumer finance. They leverage their teams' collective experience in power generation, energy conversion, controls, and system integration to develop core products focused on enabling the rapid adoption of renewable energy.

Full Harvest helps growers get the most out of a harvest and food companies save money by bringing farm excess to market. We are a B2B platform connecting large farms to food businesses to sell significantly discounted, yet perfectly good surplus and imperfectly shaped produce that would have otherwise gone to waste. Approx. 20 billion pounds of produce go to waste in the U.S. annually simply because they are not perfectly shaped for strict retailer standards. We aim to solve this problem by creating a marketplace for this unutilized edible and delicious produce. Our vision is three-fold: bring an additional revenue stream to farmers, lower the cost of healthy food production, while significantly reducing wasted food and resources. A win-win for everyone.

Backed by capital from Andreessen Horowitz, Y Combinator, and QED, OpenInvest was founded in 2015 with a core focus on helping advisors unlock the true impact of their clients’ investments. On June 29, 2021, J.P. Morgan announced that it has entered into a definitive agreement to acquire OpenInvest. OpenInvest will retain its own brand and be integrated into J.P. Morgan’s Private Bank and Wealth Management client offerings

LevelTen Energy is a company that provides renewable transaction infrastructure. It connects renewable energy buyers, advisors, and sellers and gives them the tools and services they need to get better deals done faster. Its technology-enabled marketplace connects a broader class of C & I to utility-scale projects.

For data teams looking to increase the availability of trusted data, Astronomer provides Astro, a modern data orchestration platform, powered by Apache Airflow, that enables the entire data team to build, run, and observe data pipelines-as-code. Astronomer is a commercial developer of Airflow, the de facto standard for expressing data flows as code, used by hundreds of thousands of teams across the world.

Mammoth Biosciences is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth Biosciences aims to democratize disease detection with an easy and affordable point-of-care test that allows real-time and simultaneous detection of multiple conditions. By leveraging its internal research and development and exclusive licensing to Cas12, Cas13, and Cas14, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in South San Francisco, Mammoth Biosciences is co-founded by CRISPR pioneer Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Mayfield, NFX, and 8VC, Decheng Capital and leading individual investors including Brook Byers, Tim Cook, and Jeff Huber. Mammoth has also been working on developing a rapid COVID-19 test.

Backed by capital from Andreessen Horowitz, Y Combinator, and QED, OpenInvest was founded in 2015 with a core focus on helping advisors unlock the true impact of their clients’ investments. On June 29, 2021, J.P. Morgan announced that it has entered into a definitive agreement to acquire OpenInvest. OpenInvest will retain its own brand and be integrated into J.P. Morgan’s Private Bank and Wealth Management client offerings

Full Harvest helps growers get the most out of a harvest and food companies save money by bringing farm excess to market. We are a B2B platform connecting large farms to food businesses to sell significantly discounted, yet perfectly good surplus and imperfectly shaped produce that would have otherwise gone to waste. Approx. 20 billion pounds of produce go to waste in the U.S. annually simply because they are not perfectly shaped for strict retailer standards. We aim to solve this problem by creating a marketplace for this unutilized edible and delicious produce. Our vision is three-fold: bring an additional revenue stream to farmers, lower the cost of healthy food production, while significantly reducing wasted food and resources. A win-win for everyone.

Geneticure is a Mayo Clinic backed company that has created a patented cheek-swab test that can predict individual treatment response for high blood pressure medications and devices therapies.

Geneticure is a Mayo Clinic backed company that has created a patented cheek-swab test that can predict individual treatment response for high blood pressure medications and devices therapies.