Wisconsin Alumni Research Foundation

Qolab mission is to build high quality qubits by leveraging the most advanced semiconductor manufacturing processes.

Leo Cancer Care is an innovative company based in Australia that focuses on enhancing the patient experience in cancer radiation therapy. The company has developed a specialized treatment system that emphasizes the clinical benefits of upright patient positioning, which aims to improve patient comfort and control during treatment. By integrating advanced technology with a radiotherapy machine, Leo Cancer Care's system facilitates 3D image capturing and precise control of radiation beams, ensuring that the appropriate amount of energy is delivered to targeted tissues. This approach not only simplifies the radiation therapy process but also aims to reduce the pain and costs associated with traditional chemotherapy and radiation treatments, ultimately connecting patients to centralized cancer care centers for more effective treatment options.

Ubicept is a computer vision company that specializes in developing advanced image sensors and machine learning services. By integrating next-generation image sensors with sophisticated computer vision algorithms, Ubicept enables clients to effectively capture and interpret motion across various applications. Their product offerings include photon-counting cameras, edge photon processing technologies, and a private developer portal, all designed to enhance capabilities in sectors such as mobility, robotics, aerospace, and smart manufacturing. With a focus on enabling safe perception and understanding of environments, Ubicept leverages its robust technologies to support a diverse range of industries.

Realta Fusion is an energy company focused on developing fusion energy technology to generate industrial heat and power. The company leverages advancements in super-conducting materials, plasma physics, and computing power to create a straightforward linear fusion reactor design. By utilizing abundant fuel sources, Realta Fusion aims to deliver a zero-carbon solution for energy production, offering clients a lower capital expenditure power plant option.

Pyran LLC is a chemical manufacturing company based in Madison, Wisconsin, specializing in the production of 1,5-pentanediol from renewable wood and crop waste resources, such as corn cobs. Founded in 2017, Pyran develops a starting compound that serves as a raw material for various applications, including paints, coatings, adhesives, biodegradable films, and plastics. The company focuses on replacing petroleum-based chemicals with its renewable five-carbon products, thereby enhancing the performance of everyday materials while promoting environmentally friendly and cost-efficient solutions. Pyran aims to provide the chemical industry with sustainable alternatives that address the challenges posed by diminishing resources and climate change.

Immuto Scientific is a biotechnology services company that specializes in providing analytical insights to pharmaceutical firms engaged in drug discovery. The company has developed a protein footprinting technology that automates the complex analysis of proteins, an essential component of the drug development process. This innovative technology offers a faster alternative to the industry-standard techniques for protein structure analysis, allowing drug developers to ascertain protein structures more efficiently. By streamlining these analytical processes, Immuto Scientific enhances the overall effectiveness of drug discovery efforts, particularly for protein therapeutics.

Pyran LLC is a chemical manufacturing company based in Madison, Wisconsin, specializing in the production of 1,5-pentanediol from renewable wood and crop waste resources, such as corn cobs. Founded in 2017, Pyran develops a starting compound that serves as a raw material for various applications, including paints, coatings, adhesives, biodegradable films, and plastics. The company focuses on replacing petroleum-based chemicals with its renewable five-carbon products, thereby enhancing the performance of everyday materials while promoting environmentally friendly and cost-efficient solutions. Pyran aims to provide the chemical industry with sustainable alternatives that address the challenges posed by diminishing resources and climate change.

Asto CT LLC is a company focused on developing advanced X-ray computed tomography (CT) systems specifically for equine care. Founded in 2015 and based in Madison, Wisconsin, Asto CT aims to enhance the quality of life for horses while ensuring peace of mind for their owners. The company's innovative technology allows for rapid 3D imaging of the lower limbs, head, and neck of standing horses without the need for general anesthesia, significantly improving fracture risk detection and enabling effective diagnosis of lameness and dental issues. By integrating cutting-edge robotics with fan-beam CT technology, Asto CT is at the forefront of improving diagnostic capabilities for conditions affecting horses, particularly in the distal limb and head and neck areas.

OnLume, Inc. is a medical device company based in Madison, Wisconsin, founded in 2015. The company specializes in developing intuitive and ergonomic imaging solutions for fluorescence image-guided surgery, aiming to enhance surgical precision and optimize patient outcomes. OnLume's technology provides high-quality imaging with low concentrations of fluorescent agents, allowing surgeons to visualize critical anatomy in real-time during procedures. Currently, prototypes of their systems are undergoing testing in collaboration with the Laboratory for Optical and Computational Imaging at the University of Wisconsin and the Morgridge Institute for Research. While the technology shows promise for both veterinary and human medicine, it has not yet received FDA clearance for market sale.

Stuart Therapeutics is a biotechnology company focused on developing innovative therapies for ophthalmic conditions. The company's primary offering, PolyCol, is a synthesized peptide therapeutic platform designed to repair disease-damaged helical collagen in the eye. This platform facilitates accelerated healing of epithelial cells, restoration of nerve function, and reduction of inflammation, making it a promising treatment for various ophthalmic diseases, including dry eye disease, dry age-related macular degeneration, and glaucoma. PolyCol is based on patented research from a major U.S. university, supplemented by additional intellectual property acquired by the company. Beyond ophthalmic applications, Stuart Therapeutics is also exploring PolyCol's potential in treating gastrointestinal, inflammatory, and oncology conditions.

LÜM, based in Madison, Wisconsin, operates a social music streaming application that connects emerging artists with fans and music curators. Its platform, also called LÜM, allows artists to build their brand, connect with fans, and earn support through a virtual gifting system. Fans can discover new music, customize their library, share finds, and earn rewards for supporting top artists. Curators can gather followers, create playlists, and share their discoveries with the LÜM community. The company also sells branded merchandise online. LÜM is set to integrate blockchain technology and NFTs, aiming to launch NFT Access Passes with over 10,000 artists, providing an easy entry point for the music industry into blockchain and the metaverse.

LÜM, based in Madison, Wisconsin, operates a social music streaming application that connects emerging artists with fans and music curators. Its platform, also called LÜM, allows artists to build their brand, connect with fans, and earn support through a virtual gifting system. Fans can discover new music, customize their library, share finds, and earn rewards for supporting top artists. Curators can gather followers, create playlists, and share their discoveries with the LÜM community. The company also sells branded merchandise online. LÜM is set to integrate blockchain technology and NFTs, aiming to launch NFT Access Passes with over 10,000 artists, providing an easy entry point for the music industry into blockchain and the metaverse.

PROMISS Diagnostics focuses on developing innovative diagnostic tools aimed at enhancing early detection of ovarian cancer through non-invasive testing. The company utilizes a machine-learning-based clinical diagnostic test that analyzes various objective parameters, including calcium levels, albumin, age, and menopause status, to generate a proprietary score indicating the likelihood of ovarian cancer. This approach allows clinicians to identify cancerous masses at early stages, facilitating timely intervention. PROMISS Diagnostics is dedicated to making these advanced diagnostic solutions efficacious, affordable, and accessible, thereby driving positive change in patient outcomes and increasing hope for those affected by cancer.

SimpleMachines, Inc. is a semiconductor design and development company based in Madison, Wisconsin, established in 2016. The company has developed a Software-Defined Compute platform that addresses the evolving demands of artificial intelligence, virtual reality, machine learning, robotics, and big data. As traditional CPU systems face limitations due to the end of Moore's Law, SimpleMachines offers a novel software-centric approach that allows for a programmable platform. This platform enables hardware optimization in real-time, providing the performance of custom silicon while supporting a wide range of applications. By facilitating rapid reconfiguration of hardware, SimpleMachines' technology empowers software developers to enhance application performance and meet diverse computing requirements across various industries.

HealthMyne, Inc. is a healthcare informatics company based in Madison, Wisconsin, specializing in innovative search, analytics, and imaging solutions tailored for cancer care providers. Founded in 2013, the company aims to enhance clinical decision-making by offering real-time, evidence-based imaging insights that support optimized patient care and reduce delivery costs. HealthMyne's technology enables physicians to manipulate tumor images and access electronic health records and image repositories, facilitating the diagnosis and treatment of similar cases. The company’s platform also focuses on improving patient management through features such as automatic tumor staging, dose overlays, and specialized reporting, which streamline clinical workflows and support precision medicine initiatives.

SimpleMachines, Inc. is a semiconductor design and development company based in Madison, Wisconsin, established in 2016. The company has developed a Software-Defined Compute platform that addresses the evolving demands of artificial intelligence, virtual reality, machine learning, robotics, and big data. As traditional CPU systems face limitations due to the end of Moore's Law, SimpleMachines offers a novel software-centric approach that allows for a programmable platform. This platform enables hardware optimization in real-time, providing the performance of custom silicon while supporting a wide range of applications. By facilitating rapid reconfiguration of hardware, SimpleMachines' technology empowers software developers to enhance application performance and meet diverse computing requirements across various industries.

FluGen, Inc. is a biopharmaceutical company based in Madison, Wisconsin, focused on developing vaccines to prevent diseases caused by influenza viruses. Founded in 2007, FluGen specializes in both seasonal and pandemic influenza prevention. The company offers RedeeFlu, a nasal spray vaccine, and utilizes a vaccine-loaded intradermal microneedle delivery device. FluGen's innovative approach includes the use of a live, single replication, intranasally delivered virus with a deleted M2 segment (M2SR), enhancing its ability to prevent the spread of influenza and other respiratory pathogens, including COVID-19.

Isomark, LLC is a healthcare technology company based in Madison, Wisconsin, founded in 2005. The company specializes in developing non-invasive breath monitoring technology designed to detect life-threatening infections by analyzing isotopic biomarkers in exhaled CO2 samples. Its primary product, the Canary breath analyzer, allows for rapid health assessments, providing results in as little as 30 seconds compared to traditional methods that can take hours or days. Isomark's technology aims to monitor both human and animal health, particularly addressing issues such as bovine respiratory diseases in cattle, which lead to significant economic losses annually. By allowing for quick diagnosis and monitoring, Isomark's solutions can reduce the necessity for antibiotics, ultimately enhancing meat quality for consumers and minimizing healthcare costs.

HealthMyne, Inc. is a healthcare informatics company based in Madison, Wisconsin, specializing in innovative search, analytics, and imaging solutions tailored for cancer care providers. Founded in 2013, the company aims to enhance clinical decision-making by offering real-time, evidence-based imaging insights that support optimized patient care and reduce delivery costs. HealthMyne's technology enables physicians to manipulate tumor images and access electronic health records and image repositories, facilitating the diagnosis and treatment of similar cases. The company’s platform also focuses on improving patient management through features such as automatic tumor staging, dose overlays, and specialized reporting, which streamline clinical workflows and support precision medicine initiatives.

Isomark, LLC is a healthcare technology company based in Madison, Wisconsin, founded in 2005. The company specializes in developing non-invasive breath monitoring technology designed to detect life-threatening infections by analyzing isotopic biomarkers in exhaled CO2 samples. Its primary product, the Canary breath analyzer, allows for rapid health assessments, providing results in as little as 30 seconds compared to traditional methods that can take hours or days. Isomark's technology aims to monitor both human and animal health, particularly addressing issues such as bovine respiratory diseases in cattle, which lead to significant economic losses annually. By allowing for quick diagnosis and monitoring, Isomark's solutions can reduce the necessity for antibiotics, ultimately enhancing meat quality for consumers and minimizing healthcare costs.

FluGen, Inc. is a biopharmaceutical company based in Madison, Wisconsin, focused on developing vaccines to prevent diseases caused by influenza viruses. Founded in 2007, FluGen specializes in both seasonal and pandemic influenza prevention. The company offers RedeeFlu, a nasal spray vaccine, and utilizes a vaccine-loaded intradermal microneedle delivery device. FluGen's innovative approach includes the use of a live, single replication, intranasally delivered virus with a deleted M2 segment (M2SR), enhancing its ability to prevent the spread of influenza and other respiratory pathogens, including COVID-19.

Isomark, LLC is a healthcare technology company based in Madison, Wisconsin, founded in 2005. The company specializes in developing non-invasive breath monitoring technology designed to detect life-threatening infections by analyzing isotopic biomarkers in exhaled CO2 samples. Its primary product, the Canary breath analyzer, allows for rapid health assessments, providing results in as little as 30 seconds compared to traditional methods that can take hours or days. Isomark's technology aims to monitor both human and animal health, particularly addressing issues such as bovine respiratory diseases in cattle, which lead to significant economic losses annually. By allowing for quick diagnosis and monitoring, Isomark's solutions can reduce the necessity for antibiotics, ultimately enhancing meat quality for consumers and minimizing healthcare costs.

Holos, Inc. is a company that specializes in spatial computing, providing a platform designed for educators and students to create and learn in immersive 3D environments. Founded in 2015 and based in Madison, Wisconsin, Holos offers a suite of user-friendly, no-code tools that enable users to develop training content in Augmented Reality. Its platform functions as a 3D equivalent of traditional presentation software, allowing users to integrate photos, videos, text, and 3D models into virtual spaces. Holos also features a collaborative "magic table" for presenting content and a library of pre-vetted 3D learning experiences. The solutions are designed to operate on desktop VR headsets, catering to both educational settings and technical training for critical sectors.

StudyBlue, Inc. is an educational technology company that provides a collaborative learning platform designed to enhance student engagement and academic success. Founded in 2006 and based in San Francisco, California, the company offers a mobile learning platform that enables students to create, share, and compare study materials. Through its Digital Backpack, StudyBlue allows users to store and access notes, images, audio files, and personalized practice quizzes, facilitating both individual and group study. The platform features a shared library of user-generated content, which includes flashcards, study guides, and other resources tailored for various educational levels, from high school to college and beyond. In December 2008, the company changed its name from The Class Connection, LLC to StudyBlue, Inc., and it has operated as a subsidiary of Chegg, Inc. since July 2018.

FluGen, Inc. is a biopharmaceutical company based in Madison, Wisconsin, focused on developing vaccines to prevent diseases caused by influenza viruses. Founded in 2007, FluGen specializes in both seasonal and pandemic influenza prevention. The company offers RedeeFlu, a nasal spray vaccine, and utilizes a vaccine-loaded intradermal microneedle delivery device. FluGen's innovative approach includes the use of a live, single replication, intranasally delivered virus with a deleted M2 segment (M2SR), enhancing its ability to prevent the spread of influenza and other respiratory pathogens, including COVID-19.

Madison Vaccines, Inc. is a biopharmaceutical company based in the United States that specializes in the development of therapeutic plasmid DNA vaccines, specifically targeting prostate cancer and bone metastases. The company is engaged in creating two distinct vaccines aimed at treating prostate cancer and is also developing a diagnostic test to identify patients who would benefit from these therapies. Madison Vaccines' immune-activating therapies are designed to stimulate the immune system to eradicate residual tumor cells before they progress to overt bone metastases, thus delaying the need for castration therapies and improving the chances of a cure at an early stage of the disease.

StudyBlue, Inc. is an educational technology company that provides a collaborative learning platform designed to enhance student engagement and academic success. Founded in 2006 and based in San Francisco, California, the company offers a mobile learning platform that enables students to create, share, and compare study materials. Through its Digital Backpack, StudyBlue allows users to store and access notes, images, audio files, and personalized practice quizzes, facilitating both individual and group study. The platform features a shared library of user-generated content, which includes flashcards, study guides, and other resources tailored for various educational levels, from high school to college and beyond. In December 2008, the company changed its name from The Class Connection, LLC to StudyBlue, Inc., and it has operated as a subsidiary of Chegg, Inc. since July 2018.

Isomark, LLC is a healthcare technology company based in Madison, Wisconsin, founded in 2005. The company specializes in developing non-invasive breath monitoring technology designed to detect life-threatening infections by analyzing isotopic biomarkers in exhaled CO2 samples. Its primary product, the Canary breath analyzer, allows for rapid health assessments, providing results in as little as 30 seconds compared to traditional methods that can take hours or days. Isomark's technology aims to monitor both human and animal health, particularly addressing issues such as bovine respiratory diseases in cattle, which lead to significant economic losses annually. By allowing for quick diagnosis and monitoring, Isomark's solutions can reduce the necessity for antibiotics, ultimately enhancing meat quality for consumers and minimizing healthcare costs.

Madison Vaccines, Inc. is a biopharmaceutical company based in the United States that specializes in the development of therapeutic plasmid DNA vaccines, specifically targeting prostate cancer and bone metastases. The company is engaged in creating two distinct vaccines aimed at treating prostate cancer and is also developing a diagnostic test to identify patients who would benefit from these therapies. Madison Vaccines' immune-activating therapies are designed to stimulate the immune system to eradicate residual tumor cells before they progress to overt bone metastases, thus delaying the need for castration therapies and improving the chances of a cure at an early stage of the disease.

Silatronix, Inc. is a company that specializes in the development of organosilicon compounds and formulations for energy storage applications. Founded in 2007 and based in Madison, Wisconsin, Silatronix focuses on creating organosilicon electrolytes designed for use in rechargeable and non-rechargeable lithium-ion batteries, as well as in ultracapacitors. The company's patented materials enhance battery performance by extending cell life, increasing capacity, and enabling operation across a broader temperature range. These advancements allow for the safe use of higher charge voltages, making Silatronix's products suitable for various applications, including portable electronics, electric vehicles, and large-scale energy storage systems.

NeuWave Medical is a company based in Madison, Wisconsin, that specializes in the development of energy-based minimally invasive medical devices. Founded in 2004 by a team of engineers and physician-scientists, NeuWave Medical is dedicated to addressing clinical needs through innovative solutions that are both effective and minimally invasive. The company aims to create high-quality devices that are preferred by leading physicians and medical centers worldwide, focusing on treating a variety of serious medical conditions.

Cellular Dynamics International Inc., (CDI) is a developer and manufacturer of fully functioning cells in industrial quantities to precise specifications. CDI's proprietary products include true human cells in multiple cell types (iCell products), human induced pluripotent stem cells (iPSCs) and custom iPSCs and iCell products (MyCell Products). CDI's products provide standardized, easy-to-use, cost-effective access to the human cell, the smallest fully functioning operating unit of human biology. Customers use our products, among other purposes, for drug discovery and screening, to test the safety and efficacy of their small molecule and biological drug candidates, for stem cell banking, and in the research and development of cellular therapeutics.

NeuWave Medical is a company based in Madison, Wisconsin, that specializes in the development of energy-based minimally invasive medical devices. Founded in 2004 by a team of engineers and physician-scientists, NeuWave Medical is dedicated to addressing clinical needs through innovative solutions that are both effective and minimally invasive. The company aims to create high-quality devices that are preferred by leading physicians and medical centers worldwide, focusing on treating a variety of serious medical conditions.

Deltanoid Pharmaceuticals, Inc. is a biopharmaceutical company based in Madison, Wisconsin, dedicated to the research, development, and commercialization of innovative therapies for various human diseases. Founded in 1999, the company specializes in vitamin D analogs and other compounds, primarily focusing on treatments for renal diseases, osteoporosis, and skin conditions. Notably, Deltanoid's lead product, DP001, targets secondary hyperparathyroidism in patients with chronic kidney disease undergoing hemodialysis, while another product, DP006, is aimed at treating acne. The company leverages raw university inventions and has established partnerships to advance its drug development initiatives, including a collaboration with Novadiol, Inc. for the development of a vitamin D therapy. Deltanoid's mission is to enhance health outcomes by unlocking the potential of vitamin D receptor-based therapies.

Mithridion, Inc. is a biopharmaceutical company based in Madison, Wisconsin, that specializes in discovering and developing small molecule drugs aimed at addressing unmet medical needs associated with central nervous system disorders. Founded in 2004, the company focuses primarily on serious chronic neurodegenerative diseases, including Alzheimer's disease and schizophrenia. Its drug portfolio features candidates designed for treating cognitive impairments and blocking disease processes in conditions such as Progressive Supranuclear Palsy. Notable projects include MCD-386CR, which targets neurodegenerative diseases, and MCD-386/glycopyrrolate, aimed at preventing Alzheimer's in genetically defined presymptomatic mutation carriers. Additionally, the company is developing MI-08-016/035 for common neurodegenerative diseases and MI-10-022 to address significant unmet needs in schizophrenia.

OpGen, Inc. is a precision medicine company focused on developing molecular diagnostics and informatics to address infectious diseases. Headquartered in Gaithersburg, Maryland, OpGen offers a range of products designed to provide clinicians with rapid and actionable information regarding life-threatening infections, ultimately aiming to enhance patient outcomes and reduce the spread of multidrug-resistant organisms (MDROs). Its key offerings include the Acuitas AMR Gene Panel, which detects bacterial nucleic acids and genetic markers of antimicrobial resistance, and the QuickFISH and PNA FISH products for pathogen identification in blood cultures. Additionally, OpGen provides the Acuitas Lighthouse informatics system, a cloud-based platform that integrates clinical lab results with patient and hospital data to support the management of antimicrobial-resistant infections. The company collaborates with the New York State Department of Health to develop solutions for detecting and tracking such infections in healthcare settings. Established in 2001, OpGen continues to innovate in addressing the critical challenge of antibiotic resistance through its advanced molecular microbiology solutions.

Roche NimbleGen is a biotechnology company headquartered in Madison, Wisconsin, that specializes in providing products and services for the life science research market. The company offers a range of solutions including the SeqCap EZ system, which enhances exome enrichment in a single test tube, as well as various library construction kits and reagents. Roche NimbleGen's SeqCap Epi system focuses on DNA methylation assessment, providing tools for single-base resolution analysis. The company utilizes its proprietary Maskless Array Synthesis technology to manufacture high-density DNA microarrays, improving the quality and yield of DNA sequencing data. Additionally, Roche NimbleGen offers software tools such as SignalMap for genomic data visualization and NimbleDesign for library design, alongside comprehensive online technical support. Established in 1999, Roche NimbleGen operates as a subsidiary of Roche Holding AG, emphasizing research and innovation in genomic technologies.

Roche NimbleGen is a biotechnology company headquartered in Madison, Wisconsin, that specializes in providing products and services for the life science research market. The company offers a range of solutions including the SeqCap EZ system, which enhances exome enrichment in a single test tube, as well as various library construction kits and reagents. Roche NimbleGen's SeqCap Epi system focuses on DNA methylation assessment, providing tools for single-base resolution analysis. The company utilizes its proprietary Maskless Array Synthesis technology to manufacture high-density DNA microarrays, improving the quality and yield of DNA sequencing data. Additionally, Roche NimbleGen offers software tools such as SignalMap for genomic data visualization and NimbleDesign for library design, alongside comprehensive online technical support. Established in 1999, Roche NimbleGen operates as a subsidiary of Roche Holding AG, emphasizing research and innovation in genomic technologies.

Realta Fusion is an energy company focused on developing fusion energy technology to generate industrial heat and power. The company leverages advancements in super-conducting materials, plasma physics, and computing power to create a straightforward linear fusion reactor design. By utilizing abundant fuel sources, Realta Fusion aims to deliver a zero-carbon solution for energy production, offering clients a lower capital expenditure power plant option.