VCapital

VCapital is a venture capital investment firm based in Chicago, Illinois, founded in 2015. The firm specializes in identifying early-stage, high-quality venture capital opportunities with significant growth potential, particularly in the technology, medical, and science sectors. With a strong emphasis on research and thorough due diligence, VCapital provides operational support and active guidance to entrepreneurs to enhance their chances of success. The firm focuses on sectors such as information technology, software-as-a-service, mobile, big data, cleantech, digital health, life sciences, and education technology, primarily targeting investments in the Midwest. Additionally, VCapital offers a flexible service structure to assist professional investment advisors and individuals looking to diversify their portfolios and meet their wealth management objectives through venture capital investments.

James Vaughan

Co-Founder and Managing Principal

22 past transactions

SentiAR

Series B in 2023
SentiAR, Inc. is a digital health company based in St. Louis, Missouri, specializing in 3D augmented reality solutions for interventional medical procedures. Founded in 2017 as a spin-off from Washington University, SentiAR has developed a platform that offers real-time holographic visualization of patients' anatomical structures and catheter locations. This technology integrates data from CT, MRI, and real-time mapping systems to create a controllable 3D holographic interface. The platform aims to enhance the delivery of care by allowing clinicians to visualize complex cardiac anatomy directly over the patient, thereby improving the treatment of cardiac arrhythmias during catheterization procedures. SentiAR is in the process of preparing its platform for submission to the FDA.

Avenda Health

Series B in 2022
Avenda Health Inc. develops an artificial intelligence-based focal laser ablation system specifically for treating prostate cancer. The system integrates a fiber-optic laser, a disposable sensor, and a feedback control mechanism, along with software that combines prostate imaging and biopsy data. This technology allows for the treatment of cancer under local anesthesia, utilizing magnetic resonance imaging-ultrasound fusion for enhanced image guidance. Incorporated in 2017 and based in Santa Monica, California, Avenda Health has also created an AI decision support platform, known as Unfold AI, which generates synthetic spatial maps of cancer. This platform synthesizes a patient's diagnostic information, including imaging and pathology, to assist surgeons and oncologists in making better-informed decisions, ultimately aiming to improve clinical outcomes for patients.

ATLAS Space Operations

Series B in 2022
ATLAS Space Operations, Inc. specializes in revolutionizing satellite communications through its innovative software platform. Founded in 2015 and headquartered in Traverse City, Michigan, the company offers the ATLAS Freedom Software Platform, a cloud-based space management and control system. This platform enables users to gather and process data from space efficiently, featuring capabilities such as flexible scheduling, cloud processing, and integration with AWS services. ATLAS also operates a global network of antennas to provide affordable and scalable ground communication solutions. With a focus on improving the accessibility and affordability of space-based communications, ATLAS aims to transform the industry and enhance how data from satellites is utilized on Earth.

EeroQ

Seed Round in 2022
EeroQ is a company focused on the design and development of quantum computer chips, specifically utilizing a novel approach that involves trapping and controlling individual electrons on superfluid helium. This technology, which forms the basis for qubits, aims to harness the unique properties of electrons to deliver powerful quantum computing capabilities. EeroQ's core technology is patent-protected and was developed in collaboration with Michigan State University. Founded with the goal of constructing a large-scale quantum computer, EeroQ is positioned to advance this field after overcoming previous technical limitations that hindered similar efforts in the late 1990s. Additionally, the company is committed to establishing ethical and policy guidelines to ensure that quantum computing has a positive societal impact.

InRule Technology

Venture Round in 2021
InRule Technology, Inc. is a software company that specializes in developing a business rules management system (BRMS) designed to help organizations automate complex decision-making processes. Founded in 2002 and based in Chicago, Illinois, InRule provides a comprehensive solution that includes tools for authoring, managing, and executing business rules. Its offerings encompass irAuthor for defining rule applications, irVerify for testing and debugging, irStudio for developers, and irSDK for integration into existing systems. Additionally, InRule features irServer for performance monitoring and message handling, irCatalog for rule management, and irWord for authoring executable rules within Microsoft Word. The platform supports various environments, including JavaScript, Microsoft Dynamics CRM, Microsoft Azure, and Salesforce. By empowering business users with a low-code platform and advanced features such as real-time data processing and extensive API capabilities, InRule enhances decision-making across industries such as insurance, banking, healthcare, government, and manufacturing, ultimately driving operational efficiency and superior business outcomes.

SentiAR

Series A in 2021
SentiAR, Inc. is a digital health company based in St. Louis, Missouri, specializing in 3D augmented reality solutions for interventional medical procedures. Founded in 2017 as a spin-off from Washington University, SentiAR has developed a platform that offers real-time holographic visualization of patients' anatomical structures and catheter locations. This technology integrates data from CT, MRI, and real-time mapping systems to create a controllable 3D holographic interface. The platform aims to enhance the delivery of care by allowing clinicians to visualize complex cardiac anatomy directly over the patient, thereby improving the treatment of cardiac arrhythmias during catheterization procedures. SentiAR is in the process of preparing its platform for submission to the FDA.

Rejuvenate Bio

Series A in 2021
Rejuvenate Bio Inc is a biotechnology company based in Brookline, Massachusetts, founded in 2017. The company focuses on developing gene therapies aimed at increasing the health and lifespan of domesticated animals, particularly dogs. Its innovative therapies utilize new DNA instructions to provide anti-aging treatments and address specific diseases in pets. The foundation of Rejuvenate Bio's research is rooted in work from the Wyss Institute at Harvard Medical School, and the company has established a gene therapy pipeline that targets chronic age-related diseases. By leveraging clinically validated gene targets and effective delivery methods, Rejuvenate Bio aims for long-lasting and well-tolerated gene expression, ultimately enhancing the quality of life for both animals and potentially humans facing chronic health challenges.

Ocient

Series B in 2021
Ocient Inc. is a Chicago-based company that specializes in analytical software solutions for database management. Founded in 2018, Ocient has developed a data analytics platform capable of rapidly analyzing massive datasets, ranging from tens of terabytes to exabytes, which can contain trillions or quadrillions of rows. The platform is designed to efficiently ingest billions of rows per second while filtering and computing aggregate results at speeds of up to trillions of rows per second. This capability allows organizations to effectively leverage large datasets, enabling them to gain insights at scale and with high velocity.

EDJX

Convertible Note in 2020
EDJX is focused on creating a decentralized edge computing platform aimed at addressing the growing demand for efficient data processing. This platform offers ultra-low latency capabilities and serverless computing, enabling developers to build secure Internet of Things (IoT) and machine-to-machine (M2M) applications. By directing serverless requests to the nearest devices, EDJX minimizes latency and bandwidth constraints, allowing for seamless execution of applications in isolated environments. The company also provides essential services such as content delivery networks, object storage, and DNS, enhancing the overall functionality of its edge cloud solutions.

EDJX

Convertible Note in 2020
EDJX is focused on creating a decentralized edge computing platform aimed at addressing the growing demand for efficient data processing. This platform offers ultra-low latency capabilities and serverless computing, enabling developers to build secure Internet of Things (IoT) and machine-to-machine (M2M) applications. By directing serverless requests to the nearest devices, EDJX minimizes latency and bandwidth constraints, allowing for seamless execution of applications in isolated environments. The company also provides essential services such as content delivery networks, object storage, and DNS, enhancing the overall functionality of its edge cloud solutions.

Raydiant Oximetry

Series A in 2019
Raydiant Oximetry, Inc. is a medical device company founded in 2015 and headquartered in Mountain View, California. The company focuses on improving childbirth outcomes for mothers and infants by developing a low-cost, non-invasive device that monitors fetal oxygen levels during labor. This innovative technology aims to provide real-time insights into fetal oxygenation, which can help clinicians make informed decisions and reduce the risks associated with childbirth, such as birth injuries and unnecessary cesarean sections. By enhancing patient care and potentially lowering healthcare costs, Raydiant Oximetry's device addresses critical needs in maternal and fetal health.

Raydiant Oximetry

Series A in 2019
Raydiant Oximetry, Inc. is a medical device company founded in 2015 and headquartered in Mountain View, California. The company focuses on improving childbirth outcomes for mothers and infants by developing a low-cost, non-invasive device that monitors fetal oxygen levels during labor. This innovative technology aims to provide real-time insights into fetal oxygenation, which can help clinicians make informed decisions and reduce the risks associated with childbirth, such as birth injuries and unnecessary cesarean sections. By enhancing patient care and potentially lowering healthcare costs, Raydiant Oximetry's device addresses critical needs in maternal and fetal health.

Galaxis Automotion

Series C in 2018
Galaxis technology group, founded in 2014, is a high-tech enterprise focusing on providing integrated logistics automation and robotics solutions and one-stop service. It brings together first-class technical experts and teams from home and abroad. With years of experience in logistics and technical accumulation, has more than hundreds of software copyright, and the national patent, formed the consulting including logistics system planning, software development, system integration, operation guidance, and multi-layer shuttle, high speed lift, AGV, sorting system such as the core research and development of high-end equipment manufacturing as a whole solution, the construction of logistics system can provide customers with one-stop service. High standards, refined product and service quality have kept the company in a leading position in the industry.The application cases are widely applied in more than 10 industries, such as medicine, e-commerce, clothing, books, rail,transit, automobile, etc., and more than 150 large and medium-sized modern logistics centers and production three-dimensional warehouses have been constructed, with the total investment of the project exceeding 20 billion rmb. Headquartered in Jiaxing, the group has technology r&d centers in Germany and Austria, subsidiaries or factories in eight cities of Shanghai, Beijing, Guangzhou, Wuhan, Jiaxing, Wuxi, Chengdu and Kunming. Their vision is to become the world's leading supplier of logistics robots and high-end equipment, technical service providers and system integrators. Focus on customers, continuous innovation, let the world do not hard logistics!

ATLAS Space Operations

Series A in 2018
ATLAS Space Operations, Inc. specializes in revolutionizing satellite communications through its innovative software platform. Founded in 2015 and headquartered in Traverse City, Michigan, the company offers the ATLAS Freedom Software Platform, a cloud-based space management and control system. This platform enables users to gather and process data from space efficiently, featuring capabilities such as flexible scheduling, cloud processing, and integration with AWS services. ATLAS also operates a global network of antennas to provide affordable and scalable ground communication solutions. With a focus on improving the accessibility and affordability of space-based communications, ATLAS aims to transform the industry and enhance how data from satellites is utilized on Earth.

Xaptum

Seed Round in 2018
Xaptum, Inc. is a Chicago-based company founded in 2013 that focuses on enhancing the security and management of Internet of Things (IoT) deployments. The company offers a messaging platform that facilitates the authentication, authorization, and auto-configuration of IoT devices over a single TCP connection. By providing a multi-tenant, network-as-a-service solution, Xaptum enables enterprises to connect their IoT devices to a secure, logical middle-mile network, effectively keeping them and their data shielded from the public Internet. This approach addresses key challenges in provisioning and managing IoT devices by implementing zero-touch identity and key management, thus allowing enterprises to scale their deployments securely. Xaptum's architecture is designed to simplify the complexities of IoT security, providing visibility, control, and flexibility for organizations looking to adopt and expand IoT technologies.

Padcaster

Series A in 2018
Padcaster, LLC is a manufacturer of audio-visual products and accessories designed to enhance mobile devices for video production and content creation. Established in 2012 and headquartered in Warminster, Pennsylvania, the company specializes in transforming the iPad into a multifunctional mobile production studio, allowing users to shoot, edit, and upload videos or stream live content seamlessly. Its patented hardware and software solutions cater to a diverse array of industries, including filmmaking, journalism, sports, and education. The company's offerings include video production systems, microphones, headphones, tripods, and various accessories, aimed at democratizing professional-quality video documentation for users ranging from amateur filmmakers to professional journalists and educators. With a focus on enabling individuals to realize their creative visions, Padcaster has become a widely adopted solution across different sectors.

Senko Mirco-electronics

Series A in 2018
Senko Micro-Electronics Co., Ltd specializes in the development and manufacturing of sensor chips, current detection chips, and integrated circuits. The company produces chips and linear integrated circuits specifically designed for current sensors used in hybrid electric vehicle inverters, power monitors, and electric power steering systems. Additionally, Senko offers magnetic sensor chips applicable in open-loop current sensor modules, accelerator pedals, taillight control modules, and various automation control systems for both industrial and consumer markets. The company also provides motion detection switch integrated circuits. Founded in 2013 and headquartered in Shanghai, China, Senko Micro-Electronics serves manufacturers of single-chip current detection devices across diverse applications, including transformers and battery power monitoring systems.

Weimob

Series D in 2018
Weimob Inc. is a prominent provider of cloud-based commerce and marketing solutions in China, catering primarily to small and medium-sized enterprises. Founded in 2013 and headquartered in Shanghai, the company operates through three main segments: Subscription Solutions, Merchant Solutions, and Digital Media. Its Subscription Solutions encompass various Software as a Service (SaaS) products tailored for diverse industries, including e-commerce, retail, catering, and hospitality. These solutions enable merchants to manage private traffic and enhance their online presence. The Merchant Solutions segment supports businesses in acquiring public domain traffic and achieving digital transformation through comprehensive services. Additionally, Weimob offers targeted marketing services and advertising placement to help clients optimize their promotional efforts and improve overall marketing performance. With a focus on WeChat-based applications, Weimob assists enterprises in creating cost-effective m-commerce platforms without requiring extensive software development expertise.

Alievio

Series A in 2018
Alievio, Inc. is an innovative medical device company based in Research Triangle Park, North Carolina, focused on developing solutions for glaucoma patients. The company has introduced Sollevio, a novel noninvasive device designed for the titration of postoperative intraocular pressure in individuals with refractory glaucoma. This device aims to address the complications commonly associated with traditional glaucoma surgeries and offers ophthalmologists a new tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio rebranded in June 2019 to reflect its commitment to advancing glaucoma treatment.

Alievio

Series A in 2017
Alievio, Inc. is an innovative medical device company based in Research Triangle Park, North Carolina, focused on developing solutions for glaucoma patients. The company has introduced Sollevio, a novel noninvasive device designed for the titration of postoperative intraocular pressure in individuals with refractory glaucoma. This device aims to address the complications commonly associated with traditional glaucoma surgeries and offers ophthalmologists a new tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio rebranded in June 2019 to reflect its commitment to advancing glaucoma treatment.

Intensity Therapeutics

Series A in 2016
Intensity Therapeutics, Inc. is a biotechnology company focused on developing innovative immune-based therapies for cancer treatment, specifically through a method known as in situ vaccination. Founded in 2012 and headquartered in Norwalk, Connecticut, the company specializes in the direct intratumoral injection of its proprietary drug formulation, INT230-6, which is designed to diffuse into cancer cells. This approach aims to create a robust immune response that targets not only the injected tumor but also distant, non-injected tumors. By leveraging its DfuseRx technology platform, Intensity Therapeutics is at the forefront of a clinical-stage initiative to address significant unmet needs in the treatment of solid tumor cancers, particularly in metastatic and localized disease settings.

simMachines

Non Equity Assistance in 2016
simMachines, Inc. is a Chicago-based company founded in 2012 that specializes in machine learning software, focusing on delivering explanations for predictions in various applications such as marketing, fraud detection, and compliance. The company's technology enables users to analyze both structured and unstructured data, uncovering patterns and anomalies while providing real-time recommendations. A key feature of simMachines' approach is its emphasis on transparency, allowing users to understand the underlying reasons behind predictions, which helps meet stringent AI auditing standards. Their product offerings include verifyAI, a platform for dynamic predictive segmentation, and personifyAI, a subscription service that utilizes location-based mobile data for behaviorally-driven segmentation. With a focus on similarity-oriented solutions, simMachines empowers data scientists, marketers, and business leaders to enhance decision-making and customer engagement through more relevant and targeted insights.
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