Bioventus
Bioventus LLC is a medical technology company specializing in orthobiologic solutions aimed at enhancing bone healing and managing osteoarthritis. The company offers a range of products, including active healing therapies that support the recovery of bone fractures and alleviate chronic pain associated with osteoarthritis. Its portfolio features injection therapies for osteoarthritic joints, surgical orthobiologics, and bone healing solutions that promote the body’s natural healing processes. Key offerings include the EXOGEN Ultrasound Bone Healing System and various joint fluid therapies. Bioventus is recognized for its innovative and effective products, which adhere to high quality standards and evidence-based practices. Headquartered in Durham, North Carolina, Bioventus employs around 500 people and generates approximately $240 million in annual revenue. The company operates a distribution network to make its products available to healthcare providers. Bioventus was established in 2011, evolving from the Biologics Division of Smith & Nephew.
Trice Medical, Inc. is a company that specializes in developing orthopedic diagnostic devices incorporating camera-enabled and needle-based technologies. Founded in 2011 and based in Malvern, Pennsylvania, Trice Medical aims to enhance orthopedic diagnostics for patients, physicians, and payors by providing immediate, clear answers through its innovative solutions. By enabling micro-invasive procedures that are painless and cosmetically undetectable, the company's products facilitate office-based diagnostic and therapeutic applications. Trice Medical's technology integrates miniaturized optoelectronics, optimizing clinical services and addressing the shortcomings of traditional diagnostic modalities, thereby reducing false readings and overall healthcare costs.
Misonix is a medical devices company specializing in ultrasonic surgical technology. It designs, manufactures, markets, and sells a range of invasive surgical devices that enhance clinical outcomes across various medical fields. The company’s product lineup includes innovative solutions such as BoneScalpel for precise bone sculpting, SonaStar for tissue removal, and SonicOne for wound debridement. Misonix also offers instruments for laparoscopic cutting and coagulation, liposuction tools for aesthetic procedures, and High Intensity Focused Ultrasound (HIFU) systems for tumor ablation. Its technologies are primarily utilized in neurosurgery, orthopedic surgery, plastic surgery, wound care, and maxillo-facial surgery, catering to a global market that includes the United States and the United Kingdom.
Vaporox, Inc. is a medical technology company that specializes in developing a therapeutic delivery system aimed at treating various skin wounds. The firm's flagship product, Vaporous Hyperoxia Therapy, utilizes low-frequency ultrasonic waves to create antimicrobial particles, which are continuously delivered to the wound site. This innovative approach is designed to treat a range of conditions, including diabetic foot ulcers, amputations, burns, frostbite, gangrene, pressure ulcers, and skin grafts. Founded in 2016 and headquartered in Denver, Colorado, Vaporox aims to provide effective and comfortable treatment options for patients while also helping to prevent amputations at a lower cost. The technology has received FDA clearance, underscoring its potential in the health care sector.
Bioness Inc. designs, develops, and distributes innovative medical devices aimed at helping individuals with neurological impairments regain mobility and independence. Founded in 2004 and based in Valencia, California, the company specializes in non-invasive technologies for conditions such as stroke, multiple sclerosis, traumatic brain injury, and spinal cord injury. Its product lineup includes the L300 foot drop system and the L300 Plus, which utilizes programmed electrical stimulation to activate leg muscles. Additionally, Bioness offers the H200, a wireless hand rehabilitation system that assists with hand movements, and StimRouter, an implantable device designed to alleviate chronic pain originating from peripheral nerves. Through these solutions, Bioness aims to improve the quality of life for individuals affected by various neurological disorders.
CartiHeal is a medical device company based in Kfar Sava, Israel, specializing in cartilage and bone regeneration. Founded in 2009, the company has developed the Agili-C implant, a cell-free and off-the-shelf solution designed to address focal articular cartilage and osteochondral defects. This innovative implant promotes the regeneration of hyaline cartilage and the underlying subchondral bone without the need for cells or growth factors, making it a significant advancement in the treatment of cartilage injuries. Given the limited natural healing capacity of hyaline cartilage, CartiHeal's technology offers a promising option for patients suffering from cartilage damage, which can lead to severe pain and disability if untreated. The Agili-C implant can be inserted using arthroscopic or minimally invasive techniques, facilitating faster rehabilitation and enhanced recovery outcomes for patients.
CartiHeal is a medical device company based in Kfar Sava, Israel, specializing in cartilage and bone regeneration. Founded in 2009, the company has developed the Agili-C implant, a cell-free and off-the-shelf solution designed to address focal articular cartilage and osteochondral defects. This innovative implant promotes the regeneration of hyaline cartilage and the underlying subchondral bone without the need for cells or growth factors, making it a significant advancement in the treatment of cartilage injuries. Given the limited natural healing capacity of hyaline cartilage, CartiHeal's technology offers a promising option for patients suffering from cartilage damage, which can lead to severe pain and disability if untreated. The Agili-C implant can be inserted using arthroscopic or minimally invasive techniques, facilitating faster rehabilitation and enhanced recovery outcomes for patients.
BioStructures, LLC is a medical device company founded in 2009 and based in Newport Beach, California. The company specializes in developing bioresorbable bone graft products aimed at enhancing bone regeneration and remodeling for various spinal surgical applications. Its product portfolio includes a range of offerings such as bioactive bone graft putties, mineralized collagen scaffolds, bone graft composites, and demineralized bone matrices. Additionally, BioStructures manufactures devices like bone marrow aspiration needles and hydrolyzed surgical powders. As of late 2015, BioStructures operates as a subsidiary of Bioventus LLC, focusing on advancing innovations in the field of spinal surgery.
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