Sprout Group is one of the oldest and largest institutional venture capital firms focused on emerging companies. Since its founding in 1969, Sprout Group has financed more than 350 companies and has raised nearly $3.0 billion in committed capital from leading institutional investors and individuals. In November 2000, Sprout Group closed Sprout IX, a fund totaling $1.1 billion.
CallFixie is an online platform that connects customers with a network of qualified tradespeople across Australia. This free service allows users to post jobs without incurring sign-up or subscription fees, making it accessible for anyone in need of home repair and maintenance services. Customers can easily find and receive quotes from a wide range of trades, referred to as "Fixies," through a user-friendly website and mobile applications. By streamlining the process of finding reliable service providers, CallFixie simplifies the experience of managing home repair tasks, ensuring that jobs of any size can be efficiently sorted.
Relypsa, Inc. is a biopharmaceutical company based in Redwood City, California, specializing in the development and commercialization of late-stage medicines for conditions primarily in the iron deficiency, nephrology, and cardio-renal therapeutic areas. The company is known for its product VELTASSA, a potassium binder designed to treat hyperkalemia. Relypsa focuses on discovering and developing non-absorbed polymeric drugs that address cardiovascular and renal diseases, particularly conditions that are often overlooked or undertreated. Established in 2007, Relypsa operates as a subsidiary of Vifor Pharma Ltd.
Relypsa, Inc. is a biopharmaceutical company based in Redwood City, California, specializing in the development and commercialization of late-stage medicines for conditions primarily in the iron deficiency, nephrology, and cardio-renal therapeutic areas. The company is known for its product VELTASSA, a potassium binder designed to treat hyperkalemia. Relypsa focuses on discovering and developing non-absorbed polymeric drugs that address cardiovascular and renal diseases, particularly conditions that are often overlooked or undertreated. Established in 2007, Relypsa operates as a subsidiary of Vifor Pharma Ltd.
Relypsa, Inc. is a biopharmaceutical company based in Redwood City, California, specializing in the development and commercialization of late-stage medicines for conditions primarily in the iron deficiency, nephrology, and cardio-renal therapeutic areas. The company is known for its product VELTASSA, a potassium binder designed to treat hyperkalemia. Relypsa focuses on discovering and developing non-absorbed polymeric drugs that address cardiovascular and renal diseases, particularly conditions that are often overlooked or undertreated. Established in 2007, Relypsa operates as a subsidiary of Vifor Pharma Ltd.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
Relypsa, Inc. is a biopharmaceutical company based in Redwood City, California, specializing in the development and commercialization of late-stage medicines for conditions primarily in the iron deficiency, nephrology, and cardio-renal therapeutic areas. The company is known for its product VELTASSA, a potassium binder designed to treat hyperkalemia. Relypsa focuses on discovering and developing non-absorbed polymeric drugs that address cardiovascular and renal diseases, particularly conditions that are often overlooked or undertreated. Established in 2007, Relypsa operates as a subsidiary of Vifor Pharma Ltd.
Aureon Laboratories
Series D in 2010
Aureon Laboratories is a life sciences company dedicated to enabling the advancement of predictive and personalized cancer treatment. Aureon provides objective, actionable information allowing patients and physicians to make more-informed treatment decisions through its prostate diagnostic tools.
TradeBeam is a provider of global trade management software and services that focuses on optimizing trading processes for enterprises and their partners. The company's integrated solutions enhance import and export compliance and visibility, offering features such as inventory management, shipment tracking, and supply chain event management. Additionally, TradeBeam provides global trade finance solutions, including open account management and letter of credit management, aimed at facilitating smoother and more efficient international trade operations.
Calix, Inc. provides cloud and software platforms, systems, and services that support communication service providers (CSPs) in delivering unified access networks globally, including the United States, Canada, Europe, and the Middle East. The company's offerings enable CSPs to deliver a range of services, from basic voice and data to advanced broadband solutions. Key products include Calix Cloud, which provides analytics and intelligence through network and subscriber data, and Experience eXtensible Operating System, a software platform designed for various subscriber types. Calix also offers marketing and support solutions tailored for CSP teams. Founded in 1999 and headquartered in San Jose, California, Calix aims to help service providers innovate, simplify operations, and enhance subscriber experiences, ultimately driving growth in acquisition and loyalty.
CareDx, Inc. is a precision medicine company that develops and commercializes innovative healthcare solutions for transplant patients and their caregivers. The company offers a range of products designed to enhance transplant success, including AlloSure Kidney, AlloMap Heart, and AlloSure Heart, which utilize donor-derived cell-free DNA to monitor transplant health and identify potential rejections. Additionally, CareDx provides various typing solutions for human leukocyte antigen (HLA) alleles, including Olerup SSP and TruSight HLA, as well as AlloSeq Tx for high-resolution HLA typing. The company also focuses on post-transplant monitoring with products like AlloSeq cfDNA and AlloSeq HCT for chimerism testing. CareDx enhances patient care through digital solutions such as Ottr, a transplant patient tracking software, and offers its products both directly and through third-party distributors. Founded in 1998 and headquartered in South San Francisco, California, CareDx continues to expand its portfolio through collaborations, including agreements with Illumina and Cibiltech SAS for advanced diagnostics and predictive analysis in transplantation.
Affymax is a biopharmaceutical company committed to developing novel drugs to improve the treatment of serious and often life-threatening conditions. The company's first product candidate, peginesatide (formerly known as Hematideâ„¢), has been investigated in Phase 3 trials for the potential treatment of anemia associated with chronic kidney disease (CKD). A New Drug Application (NDA) for peginesatide for the treatment of anemia associated with CKD in adult patients on dialysis is currently being reviewed by the U.S. Food and Drug Administration (FDA).
Labcyte Inc. is a laboratory instrumentation company based in San Jose, California, specializing in acoustic droplet ejection (ADE) technology for life sciences applications. Established in 2000, Labcyte develops innovative solutions for drug discovery, genomic research, cancer research, and personalized medicine through its precise liquid dispensing technology. This technology utilizes focused acoustic energy to eject nanoliter-scale droplets of fluid, allowing for high accuracy and reduced consumption of materials. Labcyte's product offerings include automation systems, laboratory workstations, and control software aimed at enhancing research efficiency and data reliability. The company operates as a subsidiary of Beckman Coulter, Inc. and maintains additional offices across multiple countries, including Canada, the United Kingdom, and Japan.
Relypsa, Inc. is a biopharmaceutical company based in Redwood City, California, specializing in the development and commercialization of late-stage medicines for conditions primarily in the iron deficiency, nephrology, and cardio-renal therapeutic areas. The company is known for its product VELTASSA, a potassium binder designed to treat hyperkalemia. Relypsa focuses on discovering and developing non-absorbed polymeric drugs that address cardiovascular and renal diseases, particularly conditions that are often overlooked or undertreated. Established in 2007, Relypsa operates as a subsidiary of Vifor Pharma Ltd.
Barricaid is a medical device company that focuses on developing innovative solutions to prevent repeat disc herniation in patients who have undergone back surgery. The company's flagship product is a bone-anchored implant designed to reduce the likelihood of reherniation and the need for reoperation in cases involving large annular defects. This implant physically blocks the annulus at the surgical defect, enhancing the surgical outcome for patients at high risk of complications after lumbar discectomy. Composed of a titanium alloy, the device securely anchors into the vertebral body, either caudally or cranially, ensuring stability and effectiveness. By addressing the challenges associated with post-surgical recovery, Barricaid aims to improve patient outcomes and reduce the incidence of further surgeries related to sciatica.
TradeBeam is a provider of global trade management software and services that focuses on optimizing trading processes for enterprises and their partners. The company's integrated solutions enhance import and export compliance and visibility, offering features such as inventory management, shipment tracking, and supply chain event management. Additionally, TradeBeam provides global trade finance solutions, including open account management and letter of credit management, aimed at facilitating smoother and more efficient international trade operations.
NeuroVista Corporation is a medical device company pioneering new technologies for the management and treatment of epilepsy, a condition that affects roughly 3 million people in the United States. The defining characteristic of epilepsy is recurrent seizures that strike without warning. Symptoms may range from brief suspension of awareness, to loss of consciousness, to violent convulsions. Unlike other neurological conditions, such as stroke or Alzheimer's disease which tend to develop later in life, epilepsy often affects people in the prime of their lives, with the majority between 15 and 64 years of age.
Spine Wave, Inc. is a manufacturer of medical devices focused on the treatment of spinal disorders. Founded in 2001 and based in Shelton, Connecticut, the company develops and markets a range of innovative products aimed at providing surgical solutions for spine surgeons and their patients. Its offerings include expandable PEEK spacers, interbody devices for posterior surgery, pivoting and lateral spacer systems, and the GraftMag Graft Delivery System for bone graft delivery. Additionally, Spine Wave produces fixation products designed for addressing degeneration, deformity, tumors, and trauma in the thoracolumbar spine, as well as anterior cervical plate systems for spinal fusion from C2-C7 and cervical spacer systems for degenerative disc disease from C2-T1. The company distributes its products through a network of distributors, emphasizing a surgeon-driven approach to product development to address real surgical challenges.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
Kalypsys provides pathway-based drug discovery and development services. The company implements discovery programs across a broad number of therapeutic areas using its automated and integrated suite of discovery technologies in biology, chemistry and informatics.
Tolerx, Inc. develops novel therapies focusing on modulating T-cell activities for treating autoimmune diseases, diabetes, and cancer. The company's products include otelixizumab, a targeted T-cell immunomodulator for treating type 1 diabetes; MTRX1011A, an anti-CD4 antibody for treating autoimmune indications; and TRX518 and TRX385, pre-clinical candidates that focuses on optimizing immune responses for treating cancer and chronic viral diseases. Tolerx, Inc., formerly known as TolerRx, Inc., was founded in 2000 and is based in Cambridge, Massachusetts.
Spine Wave, Inc. is a manufacturer of medical devices focused on the treatment of spinal disorders. Founded in 2001 and based in Shelton, Connecticut, the company develops and markets a range of innovative products aimed at providing surgical solutions for spine surgeons and their patients. Its offerings include expandable PEEK spacers, interbody devices for posterior surgery, pivoting and lateral spacer systems, and the GraftMag Graft Delivery System for bone graft delivery. Additionally, Spine Wave produces fixation products designed for addressing degeneration, deformity, tumors, and trauma in the thoracolumbar spine, as well as anterior cervical plate systems for spinal fusion from C2-C7 and cervical spacer systems for degenerative disc disease from C2-T1. The company distributes its products through a network of distributors, emphasizing a surgeon-driven approach to product development to address real surgical challenges.
CareDx, Inc. is a precision medicine company that develops and commercializes innovative healthcare solutions for transplant patients and their caregivers. The company offers a range of products designed to enhance transplant success, including AlloSure Kidney, AlloMap Heart, and AlloSure Heart, which utilize donor-derived cell-free DNA to monitor transplant health and identify potential rejections. Additionally, CareDx provides various typing solutions for human leukocyte antigen (HLA) alleles, including Olerup SSP and TruSight HLA, as well as AlloSeq Tx for high-resolution HLA typing. The company also focuses on post-transplant monitoring with products like AlloSeq cfDNA and AlloSeq HCT for chimerism testing. CareDx enhances patient care through digital solutions such as Ottr, a transplant patient tracking software, and offers its products both directly and through third-party distributors. Founded in 1998 and headquartered in South San Francisco, California, CareDx continues to expand its portfolio through collaborations, including agreements with Illumina and Cibiltech SAS for advanced diagnostics and predictive analysis in transplantation.
Radiant Medical is a private medical device company based in Redwood City, California, established in 1999. The company specializes in endovascular temperature therapy, focusing on the treatment of heart, brain, and kidney disorders. Its primary product is a single-use central venous heat exchange balloon catheter, which works in conjunction with a heat exchange cassette, a microprocessor-driven controller, and an integrated temperature sensor. This innovative system allows for the safe and rapid reduction, maintenance, and warming of a patient’s core body temperature, enhancing treatment efficacy in critical care settings.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
LeftHand Networks Inc. offers data storage systems and IP-based storage area networks (SAN). It offers iSCSI SANs that are composed of multiple storage nodes, pooled together into a single storage system; integrated storage systems; and virtual storage systems. The company also offers evaluation software, such as SAN/iQ software and virtual SAN appliance, which aggregate disparate resources into a single, larger storage system. In addition, it provides IT project solutions, including disaster recovery, business continuance, and data center virtualization; application solutions, including data protection manager, exchange server, sharepoint server, SQL server, and VMware; and industry solutions for education, government, financial services, and healthcare industry. The company offers its products through distributors and resellers in the United States, Canada, and Europe. LeftHand Networks was founded in 1999 and is headquartered in Boulder, Colorado with additional offices in Reading, United Kingdom and Zaltbommel, the Netherlands. As of November 13, 2008, LeftHand Networks Inc. operates as a subsidiary of Hewlett-Packard Company.
Direct Flow Medical is a medical device company focused on developing innovative transcatheter aortic valve replacement systems aimed at treating cardiac valve insufficiency. The company’s flagship product is a percutaneous aortic tissue valve prosthesis designed to offer a safe and effective alternative for patients, particularly those over the age of 65 who suffer from calcified aortic valves. Despite the prevalence of this condition, with approximately 1.2 million affected individuals, only around 150,000 receive surgical treatment annually. Direct Flow Medical's technology enhances patient outcomes and minimizes complications by allowing heart surgeons to perform valve replacements without invasive surgery, using repeated assessments of hemodynamic performance prior to final implantation.
Aureon Laboratories
Series B in 2005
Aureon Laboratories is a life sciences company dedicated to enabling the advancement of predictive and personalized cancer treatment. Aureon provides objective, actionable information allowing patients and physicians to make more-informed treatment decisions through its prostate diagnostic tools.
Affymax is a biopharmaceutical company committed to developing novel drugs to improve the treatment of serious and often life-threatening conditions. The company's first product candidate, peginesatide (formerly known as Hematideâ„¢), has been investigated in Phase 3 trials for the potential treatment of anemia associated with chronic kidney disease (CKD). A New Drug Application (NDA) for peginesatide for the treatment of anemia associated with CKD in adult patients on dialysis is currently being reviewed by the U.S. Food and Drug Administration (FDA).
Yipes is a data communications services provider. It was acquired in 2007 by Indian telecommunications service provider Reliance Communications. Yipes delivers scalable business-to-business and business-to-Internet IP networking services. Their regional IP network Yipes MAN seamlessly extends your company's LAN to other business locations or to business partner locations. Their Yipes NET Internet service brings the Web to your LAN at breakaway speeds. Yipes NET customers can also take advantage of Yipes' industry-leading security offering Yipes WALL managed firewall service, to safeguard their private information from the dangers of the public Internet. Yipes NAN replaces private line and frame relay services with the simplicity of Ethernet. Yipes WEB offers a full portfolio of Internet management services. Yipes TOUGH enables customers to extend the redundancy on their customer premise to the Yipes Network.
Tolerx, Inc. develops novel therapies focusing on modulating T-cell activities for treating autoimmune diseases, diabetes, and cancer. The company's products include otelixizumab, a targeted T-cell immunomodulator for treating type 1 diabetes; MTRX1011A, an anti-CD4 antibody for treating autoimmune indications; and TRX518 and TRX385, pre-clinical candidates that focuses on optimizing immune responses for treating cancer and chronic viral diseases. Tolerx, Inc., formerly known as TolerRx, Inc., was founded in 2000 and is based in Cambridge, Massachusetts.
NeuroBionics
Series A in 2004
NeuroBionics Corp. researches and develops medical devices for the treatment of neurological disorders such as Parkinson’s disease, epilepsy, obesity, and depression.
CareDx, Inc. is a precision medicine company that develops and commercializes innovative healthcare solutions for transplant patients and their caregivers. The company offers a range of products designed to enhance transplant success, including AlloSure Kidney, AlloMap Heart, and AlloSure Heart, which utilize donor-derived cell-free DNA to monitor transplant health and identify potential rejections. Additionally, CareDx provides various typing solutions for human leukocyte antigen (HLA) alleles, including Olerup SSP and TruSight HLA, as well as AlloSeq Tx for high-resolution HLA typing. The company also focuses on post-transplant monitoring with products like AlloSeq cfDNA and AlloSeq HCT for chimerism testing. CareDx enhances patient care through digital solutions such as Ottr, a transplant patient tracking software, and offers its products both directly and through third-party distributors. Founded in 1998 and headquartered in South San Francisco, California, CareDx continues to expand its portfolio through collaborations, including agreements with Illumina and Cibiltech SAS for advanced diagnostics and predictive analysis in transplantation.
TradeBeam is a provider of global trade management software and services that focuses on optimizing trading processes for enterprises and their partners. The company's integrated solutions enhance import and export compliance and visibility, offering features such as inventory management, shipment tracking, and supply chain event management. Additionally, TradeBeam provides global trade finance solutions, including open account management and letter of credit management, aimed at facilitating smoother and more efficient international trade operations.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
Sopherion Therapeutics, LLC is a privately held biopharmaceutical company headquartered in Princeton, New Jersey with offices in Cheshire, Connecticut, Estero, Florida and an operating subsidiary, Sopherion Therapeutics Canada, in Toronto, Canada. Sopherion Therapeutics LLC is a specialty biopharmaceutical company with an exclusive licensing agreement with Zeneus Pharma Ltd., now Cephalon, Inc., for the commercialization of Myocet™ (a liposome-encapsulated doxorubicin-citrate complex) in the United States and Canada. Sopherion’s current business focus is the execution of a Phase III, global, randomized, registration trial for first line therapy of invasive, metastatic breast cancer and the development and commercialization of Sopherion’s lead agent, Myocet™. Myocet is being investigated in an FDA agreed upon registration trial in combination with two other drugs, Herceptin® (Trastuzumab) and Taxol (Paclitaxel) vs. Herceptin® and Taxol alone, the current standard of care for first line HER-2-overexpressing metastatic breast cancer. Myocet™, a liposome-encapsulated doxorubicin with reduced cardiotoxicity, is a nanotechnology product that localizes into tumor vasculature and in contrast to parental doxorubicin avoids homing to the heart. This 363 patient global trial in twelve countries has as of 03/06/09 been fully recruited. Unblinding is anticipated by the summer of 2010 with NDA submission for full approval following within 6 months. Myocet® is already a registered drug in Canada, where Sopherion has commercial rights and in Europe where Cephalon has commercial rights for use in first line metastatic breast cancer in combination with cyclophosphamide.; Their Phase III trial is based on a Phase II trial, supported by Roche, which gave a 96% response rate and two and a half year median progression free survival for patients with metastatic breast cancer.
Kalypsys provides pathway-based drug discovery and development services. The company implements discovery programs across a broad number of therapeutic areas using its automated and integrated suite of discovery technologies in biology, chemistry and informatics.
Evolution Benefits specializes in enhancing financial health and employee satisfaction by creating customized employee benefit plans tailored to the specific objectives and goals of their clients. The company takes a comprehensive approach, considering the unique demographics and culture of each organization to develop a cost-effective benefits package. In addition to employee benefits strategies, Evolution Benefits also offers healthcare software and payment solutions that facilitate the administration and management of consumer-directed accounts. Their services include integration solutions for defined contribution plans, Health Savings Accounts, Health Reimbursement Arrangements, Flexible Spending Accounts, Voluntary Employee Beneficiary Associations, Pre-tax Transportation Accounts, wellness plans, and more. Through these offerings, Evolution Benefits aims to streamline the complexities of healthcare for businesses and their employees.
Affymax is a biopharmaceutical company committed to developing novel drugs to improve the treatment of serious and often life-threatening conditions. The company's first product candidate, peginesatide (formerly known as Hematideâ„¢), has been investigated in Phase 3 trials for the potential treatment of anemia associated with chronic kidney disease (CKD). A New Drug Application (NDA) for peginesatide for the treatment of anemia associated with CKD in adult patients on dialysis is currently being reviewed by the U.S. Food and Drug Administration (FDA).
Aspreva Pharmaceuticals Corp, based in Victoria, British Columbia, is a pharmaceutical company dedicated to identifying and developing new indications for existing drugs aimed at underserved patient populations. The company employs a strategy known as "indication partnering," collaborating with other pharmaceutical and biopharmaceutical firms to explore new therapeutic approvals that align with its expertise. Aspreva focuses on complex diseases and specialized patient groups, utilizing a proprietary screening program to identify late-stage and approved medications that may offer significant therapeutic benefits for uncommon conditions. Through partnerships, Aspreva acquires rights to develop these drugs, encompassing clinical research, regulatory approvals, and specialized commercialization efforts tailored to these intricate therapeutic areas.
Spiration, Inc., operating as Olympus Respiratory America, specializes in the development of medical devices aimed at treating air leaks and lung diseases. Founded in 1999 and headquartered in Redmond, Washington, the company focuses on innovative solutions for both acute and chronic lung conditions. One of its key products is the IBV valve system, a minimally invasive device designed to redirect airflow from diseased sections of the lung to healthier areas. This system is particularly beneficial for patients suffering from emphysema, prolonged air leaks, and other complications associated with damaged lungs. As of 2010, Spiration operates as a subsidiary of Olympus America Inc.
NeuroVista Corporation is a medical device company pioneering new technologies for the management and treatment of epilepsy, a condition that affects roughly 3 million people in the United States. The defining characteristic of epilepsy is recurrent seizures that strike without warning. Symptoms may range from brief suspension of awareness, to loss of consciousness, to violent convulsions. Unlike other neurological conditions, such as stroke or Alzheimer's disease which tend to develop later in life, epilepsy often affects people in the prime of their lives, with the majority between 15 and 64 years of age.
Visiogen, Inc. is an ophthalmic medical device company focused on developing innovative vision solutions for patients with cataracts, including those with presbyopia. The company's flagship product is the Synchrony dual optic accommodating intraocular lens (IOL), designed to deliver a seamless range of near, intermediate, and distance vision without the need for glasses or contact lenses. This advanced device is supplied in a pre-loaded injector to minimize lens handling during surgical procedures. Visiogen's technology has received CE Mark approval in Europe and is currently in clinical trials in the United States, aiming to enhance the quality of life for cataract patients through improved vision correction options.
Auxilium Pharmaceuticals, founded in 1999, specializes in the development and marketing of pharmaceutical products aimed at urology and sexual health disorders. The company is committed to improving patient outcomes by identifying and commercializing innovative specialty biopharmaceuticals. Over the years, Auxilium has broadened its mission to include the creation of novel treatment options for various unmet medical needs, reflecting its dedication to addressing significant health challenges in society.
Storability Software specializes in enterprise storage resource management solutions designed to simplify and centralize the management of complex, multi-site, and multi-vendor storage infrastructures. Its flagship product, the Global Storage Manager, is an open standards-based solution that empowers customers to better understand, manage, and optimize their storage investments. By utilizing Storability Software's offerings, clients can achieve increased asset utilization, improved management efficiency, enhanced quality of service, and greater availability of their storage resources.
Infinera Corporation is a global supplier of optical transport networking equipment, software, and services, specializing in photonic integration technology. The company's product offerings include modular and sled-based platforms, coherent optical transport systems, and packet transport platforms designed for a variety of network applications. Infinera's digital transport node system leverages photonic integrated circuits to enable efficient management and processing of data, supporting high-capacity optical networks. Its solutions cater to telecommunications service providers, internet content providers, cable operators, and large enterprises, among others. In addition to hardware, Infinera provides a range of support services, including technical support, installation, and professional services, to ensure optimal performance of its products. Founded in 2000 and headquartered in Sunnyvale, California, Infinera has established itself as a leader in the optical networking space.
Progen Pharmaceuticals, Inc. develops pharmaceutical products for the treatment of anti-proliferation and cancer therapeutics. The company's products are also used for the treatment of various diseases, including age-related macular degeneration, infectious diseases, inflammatory diseases, and vascular hyperplasia. Progen Pharmaceuticals, Inc. was founded in 1998 and is headquartered in Redwood City, California. Progen Pharmaceuticals, Inc. was formerly known as CellGate, Inc. As a result of the acquisition of Cellgate, Inc. by Progen Pharmaceuticals Limited, Cellgate's name was changed. As of February 7, 2008, Progen Pharmaceuticals, Inc. operates as a subsidiary of Progen Pharmaceuticals Limited (ASX: PGL).
Ilypsa is a company focused on discovering and developing pharmaceutical products for renal care, specifically targeting complications associated with chronic kidney diseases. Established in 2002 and based in Santa Clara, California, Ilypsa specializes in creating non-absorbed polymeric compounds that act as binders for phosphate and potassium. These compounds work by binding to phosphorus in the digestive tract, preventing its absorption into the body and thereby helping patients manage high blood levels of phosphorus, a condition known as hyperphosphatemia. The company's innovations are aimed at improving the quality of life for individuals suffering from kidney-related health issues.
Evolution Benefits specializes in enhancing financial health and employee satisfaction by creating customized employee benefit plans tailored to the specific objectives and goals of their clients. The company takes a comprehensive approach, considering the unique demographics and culture of each organization to develop a cost-effective benefits package. In addition to employee benefits strategies, Evolution Benefits also offers healthcare software and payment solutions that facilitate the administration and management of consumer-directed accounts. Their services include integration solutions for defined contribution plans, Health Savings Accounts, Health Reimbursement Arrangements, Flexible Spending Accounts, Voluntary Employee Beneficiary Associations, Pre-tax Transportation Accounts, wellness plans, and more. Through these offerings, Evolution Benefits aims to streamline the complexities of healthcare for businesses and their employees.
Sirna Therapeutics is a biotechnology company focused on developing therapies based on RNA interference (RNAi), a groundbreaking scientific discovery with the potential to transform disease treatment. By harnessing the capabilities of RNAi, Sirna Therapeutics aims to create innovative solutions that address various illnesses, positioning itself at the forefront of this emerging field. The company's commitment to advancing RNAi-based therapies highlights its role in the evolving landscape of medical treatment, with the goal of improving patient outcomes through targeted interventions.
LeftHand Networks Inc. offers data storage systems and IP-based storage area networks (SAN). It offers iSCSI SANs that are composed of multiple storage nodes, pooled together into a single storage system; integrated storage systems; and virtual storage systems. The company also offers evaluation software, such as SAN/iQ software and virtual SAN appliance, which aggregate disparate resources into a single, larger storage system. In addition, it provides IT project solutions, including disaster recovery, business continuance, and data center virtualization; application solutions, including data protection manager, exchange server, sharepoint server, SQL server, and VMware; and industry solutions for education, government, financial services, and healthcare industry. The company offers its products through distributors and resellers in the United States, Canada, and Europe. LeftHand Networks was founded in 1999 and is headquartered in Boulder, Colorado with additional offices in Reading, United Kingdom and Zaltbommel, the Netherlands. As of November 13, 2008, LeftHand Networks Inc. operates as a subsidiary of Hewlett-Packard Company.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
Watercove Networks is a provider of data networking infrastructure designed specifically for wireless service providers aiming to deploy next-generation mobile data services efficiently and profitably. Established in 2000, the company offers the Mobile Data Service System, which enables operators to accelerate the rollout of high-speed data services in 2.5G and 3G environments. This system addresses the challenges associated with legacy routing-centric networks, facilitating a smooth transition to modern technologies without the need for expensive upgrades. The company is led by a seasoned management team with extensive experience in the telecommunications and data networking sectors, supported by a board of directors comprising industry veterans. Watercove Networks has secured significant financing from reputable investors, allowing it to enhance its innovative solutions and drive growth in the emerging mobile data market.
Tolerx, Inc. develops novel therapies focusing on modulating T-cell activities for treating autoimmune diseases, diabetes, and cancer. The company's products include otelixizumab, a targeted T-cell immunomodulator for treating type 1 diabetes; MTRX1011A, an anti-CD4 antibody for treating autoimmune indications; and TRX518 and TRX385, pre-clinical candidates that focuses on optimizing immune responses for treating cancer and chronic viral diseases. Tolerx, Inc., formerly known as TolerRx, Inc., was founded in 2000 and is based in Cambridge, Massachusetts.
Barricaid is a medical device company that focuses on developing innovative solutions to prevent repeat disc herniation in patients who have undergone back surgery. The company's flagship product is a bone-anchored implant designed to reduce the likelihood of reherniation and the need for reoperation in cases involving large annular defects. This implant physically blocks the annulus at the surgical defect, enhancing the surgical outcome for patients at high risk of complications after lumbar discectomy. Composed of a titanium alloy, the device securely anchors into the vertebral body, either caudally or cranially, ensuring stability and effectiveness. By addressing the challenges associated with post-surgical recovery, Barricaid aims to improve patient outcomes and reduce the incidence of further surgeries related to sciatica.
Aureon Laboratories
Series A in 2002
Aureon Laboratories is a life sciences company dedicated to enabling the advancement of predictive and personalized cancer treatment. Aureon provides objective, actionable information allowing patients and physicians to make more-informed treatment decisions through its prostate diagnostic tools.
Epocrates specializes in developing mobile and online clinical information and decision support tools designed for healthcare professionals. Its software enables users, including a significant portion of U.S. physicians and medical students, to access critical information quickly and confidently at the point of care. The offerings include an integrated diagnostic suite, a comprehensive drug reference guide, and resources for ICD-9 and CPT codes, along with various medical terminology guides. Additionally, Epocrates provides market research, formulary hosting, and medical education services, further supporting healthcare providers in delivering informed patient care.
Sensys Medical
Series D in 2002
Sensys Medical develops a non-invasive blood glucose monitor that used near-infrared diffuse reflectance spectroscopy.
Internet Photonics, Inc. is a growth-oriented company specializing in optical Ethernet transport and switching products designed for telecom service providers. The company has developed the first carrier-grade Intelligent Wavelength Platforms, enabling network operators, including service providers and cable multiple system operators (MSOs), to offer high-bandwidth data services in conjunction with their existing legacy services. By focusing on innovative solutions in optical networking, Internet Photonics aims to enhance the capabilities of telecom infrastructure and support the increasing demand for efficient data transmission.
Blue Falcon provides the most cost-effective, high quality, and easily deployed digital content delivery solutions. With centralized network control, decentralized distribution, and integration with industry leading DRM solutions, Blue Falcon provides groundbreaking digital delivery efficiencies within a securely managed network. Blue Falcon's suite of solutions meets a broad range of digital delivery needs including: live audio and video streaming, on-demand music and movies, and large file and application downloads. The company's target customer base includes digital content providers, traditional/web broadcasters, and Global 1000 corporations. Blue Falcon's rapidly growing customer base includes Radio Free Virgin and Salem Communications. Corporate headquarters are in downtown Los Angeles in the historic Bradbury Building.
Visiogen, Inc. is an ophthalmic medical device company focused on developing innovative vision solutions for patients with cataracts, including those with presbyopia. The company's flagship product is the Synchrony dual optic accommodating intraocular lens (IOL), designed to deliver a seamless range of near, intermediate, and distance vision without the need for glasses or contact lenses. This advanced device is supplied in a pre-loaded injector to minimize lens handling during surgical procedures. Visiogen's technology has received CE Mark approval in Europe and is currently in clinical trials in the United States, aiming to enhance the quality of life for cataract patients through improved vision correction options.
Storability Software specializes in enterprise storage resource management solutions designed to simplify and centralize the management of complex, multi-site, and multi-vendor storage infrastructures. Its flagship product, the Global Storage Manager, is an open standards-based solution that empowers customers to better understand, manage, and optimize their storage investments. By utilizing Storability Software's offerings, clients can achieve increased asset utilization, improved management efficiency, enhanced quality of service, and greater availability of their storage resources.
Labcyte Inc. is a laboratory instrumentation company based in San Jose, California, specializing in acoustic droplet ejection (ADE) technology for life sciences applications. Established in 2000, Labcyte develops innovative solutions for drug discovery, genomic research, cancer research, and personalized medicine through its precise liquid dispensing technology. This technology utilizes focused acoustic energy to eject nanoliter-scale droplets of fluid, allowing for high accuracy and reduced consumption of materials. Labcyte's product offerings include automation systems, laboratory workstations, and control software aimed at enhancing research efficiency and data reliability. The company operates as a subsidiary of Beckman Coulter, Inc. and maintains additional offices across multiple countries, including Canada, the United Kingdom, and Japan.
Captura was founded in September, 1994 to provide large companies with comprehensive solutions and services for managing their costs and decreasing processing costs. The company continues this tradition today with its Total Expense Management solutions. Captura's Total Expense Management Solutions allow companies to automate expense management by using Web-based technology and capture essential financial data that can help them make sound, timely business decisions. Captura's Total Expense Management Solutions can be deployed globally to a company's users via a standard web browser and Internet connection. The applications themselves are centrally hosted and maintained according to one of Captura's available Deployment Options. Captura enhances its sophisticated solutions with strategic alliances in the financial, software, travel, application service provider (ASP) and communications industries that help Captura customers design and deploy integrated solutions for capturing and analyzing expense data from throughout the enterprise.
Spiration, Inc., operating as Olympus Respiratory America, specializes in the development of medical devices aimed at treating air leaks and lung diseases. Founded in 1999 and headquartered in Redmond, Washington, the company focuses on innovative solutions for both acute and chronic lung conditions. One of its key products is the IBV valve system, a minimally invasive device designed to redirect airflow from diseased sections of the lung to healthier areas. This system is particularly beneficial for patients suffering from emphysema, prolonged air leaks, and other complications associated with damaged lungs. As of 2010, Spiration operates as a subsidiary of Olympus America Inc.
Kalypsys provides pathway-based drug discovery and development services. The company implements discovery programs across a broad number of therapeutic areas using its automated and integrated suite of discovery technologies in biology, chemistry and informatics.
DynamicSoft provides carrier-class infrastructure software for packet-based wireline and wireless communications networks. The company's infrastructure solutions enable carriers and communications application service providers to deploy telephony applications and converged services over Internet protocol-based networks. Its dynamicsoft Service Engine allows mobile carriers to deliver voice and data services over packet network, as well as provides a migration path to various IP 3G network environments; supports various services, such as voice, multimedia messaging, instant messaging, and presence; and consolidates common functions, which include customer data storage, authentication, authorization, provisioning, and service interaction. The company was founded in 1998 and is based in East Hanover, New Jersey.
Silicon Access Networks is a provider of an ultra-high performance chipsets for terabit routers and communication silicon to the networking and telecommunications market.
Gryphon Therapeutics is a biopharmaceutical company focused on the development of performance-enhanced protein therapeutics. Its products combine chemically synthesized protein backbones with polyethylene glycols such as molecules to create potent medications.
Funded in May 2000, Opthos capitalizes on newly-developed, highly innovative technologies. Their goal is to deliver optical networking products that satisfy the overwhelming need by communications carriers for high agility, very low cost solutions.
In May 2007, Protedyne became a wholly owned subsidiary of Laboratory Corporation of America www.labcorp.com. Protedyne brings serious laboratory automation to LabCorp’s diagnostic testing facilities nationwide. Using the design principles of industrial automation, Protedyne’s automation systems combine powerful laboratory robotic hardware with a software infrastructure that ensures complete data management and process tracking. Protedyne is ISO 13485:2003 Registered with BSI Management Systems.
Storability Software specializes in enterprise storage resource management solutions designed to simplify and centralize the management of complex, multi-site, and multi-vendor storage infrastructures. Its flagship product, the Global Storage Manager, is an open standards-based solution that empowers customers to better understand, manage, and optimize their storage investments. By utilizing Storability Software's offerings, clients can achieve increased asset utilization, improved management efficiency, enhanced quality of service, and greater availability of their storage resources.
Atesto Technologies
Series B in 2001
Atesto is an automated Web testing service that enables organizations to develop, deploy and monitor Web applications without needing to license, install and manage software and hardware systems and infrastructure. The company’s software suite, Atesto Functional Test, tests and validates complex, static and dynamic Web applications. The company also offers load testing and monitoring services, to address performance and application maintenance needs. The Automated Load Test services simulate complex real-life application scenarios using live Internet traffic from a globally distributed network and the Response Watch service features periodic transaction and Web application monitoring capability from global locations. Both services include detailed, real-time, online reports on application performance and analysis.
Infinera Corporation is a global supplier of optical transport networking equipment, software, and services, specializing in photonic integration technology. The company's product offerings include modular and sled-based platforms, coherent optical transport systems, and packet transport platforms designed for a variety of network applications. Infinera's digital transport node system leverages photonic integrated circuits to enable efficient management and processing of data, supporting high-capacity optical networks. Its solutions cater to telecommunications service providers, internet content providers, cable operators, and large enterprises, among others. In addition to hardware, Infinera provides a range of support services, including technical support, installation, and professional services, to ensure optimal performance of its products. Founded in 2000 and headquartered in Sunnyvale, California, Infinera has established itself as a leader in the optical networking space.
MarketFirst Software, Inc. develops software and hosted e-marketing solutions that allows organizations to execute marketing campaigns over the Internet. The company's solutions include an e-marketing software platform; software templates for e-marketing campaigns called eMarketing Blueprints; a hosted service; and strategic e-marketing consulting and implementation service. The company was founded in 1996 and is based in Mountain View, California.
Watercove Networks is a provider of data networking infrastructure designed specifically for wireless service providers aiming to deploy next-generation mobile data services efficiently and profitably. Established in 2000, the company offers the Mobile Data Service System, which enables operators to accelerate the rollout of high-speed data services in 2.5G and 3G environments. This system addresses the challenges associated with legacy routing-centric networks, facilitating a smooth transition to modern technologies without the need for expensive upgrades. The company is led by a seasoned management team with extensive experience in the telecommunications and data networking sectors, supported by a board of directors comprising industry veterans. Watercove Networks has secured significant financing from reputable investors, allowing it to enhance its innovative solutions and drive growth in the emerging mobile data market.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
Silicon Access Networks is a provider of an ultra-high performance chipsets for terabit routers and communication silicon to the networking and telecommunications market.
Epocrates specializes in developing mobile and online clinical information and decision support tools designed for healthcare professionals. Its software enables users, including a significant portion of U.S. physicians and medical students, to access critical information quickly and confidently at the point of care. The offerings include an integrated diagnostic suite, a comprehensive drug reference guide, and resources for ICD-9 and CPT codes, along with various medical terminology guides. Additionally, Epocrates provides market research, formulary hosting, and medical education services, further supporting healthcare providers in delivering informed patient care.
Vasca is a medical device company that provides technologies to improve body access for therapeutic interventions in the United States and European Union. The company develops, manufactures, and markets LifeSite, a subcutaneous device that combines a valve with cannulas, which are used for the treatment of chronic renal failure. Vasca was founded in 1996 and is based in Tewksbury, Massachusetts, United States.
DynamicSoft provides carrier-class infrastructure software for packet-based wireline and wireless communications networks. The company's infrastructure solutions enable carriers and communications application service providers to deploy telephony applications and converged services over Internet protocol-based networks. Its dynamicsoft Service Engine allows mobile carriers to deliver voice and data services over packet network, as well as provides a migration path to various IP 3G network environments; supports various services, such as voice, multimedia messaging, instant messaging, and presence; and consolidates common functions, which include customer data storage, authentication, authorization, provisioning, and service interaction. The company was founded in 1998 and is based in East Hanover, New Jersey.
eFinance's innovative solutions enable companies to quickly and accurately gauge the financial soundness of their customers at each step of the financial supply chain. Their solutions strengthen the credit evaluation process and enable customers to better manage transaction workflow. Customers leverage eFinance technology to increase revenue and profitability while expanding their end customer base and improving customer retention and satisfaction.
MuseumShop.com has established partnerships and affiliations with more than 44 museums worldwide and showcases more than 3,500 products ranging from home decor to fine prints.
Funded in May 2000, Opthos capitalizes on newly-developed, highly innovative technologies. Their goal is to deliver optical networking products that satisfy the overwhelming need by communications carriers for high agility, very low cost solutions.
CarrierPoint designs and develops web-based logistics software that enables shippers and carriers to communicate with each other. The company’s range of solutions consists of compliance, monitoring, collaboration, and integration. Compliance offers eRFQ, contract management, shipment rating, dispatch, scheduling, and freight payment services. Monitoring offers status tracking, delivery confirmation, dock delivery, and analysis reports. Collaboration consists of planned and unplanned collaboration. Integration consists of OMSI and professional services. CarrierPoint was founded in 1999 by Cliff Isaacson and John Thomson and is based in Georgia.
Edupoint specializes in providing a comprehensive data management solution for K-12 education through its Synergy® Education Platform. This platform includes Synergy SIS, a robust student information system, Synergy LMS for learning management and assessment, and Synergy SE for managing special education. By addressing the diverse needs of K-12 school districts, Edupoint enables educators to connect various stakeholders with essential data, thereby enhancing decision-making processes and promoting improved student performance and achievement.
Excess Bandwidth Corp. specializes in developing algorithms that facilitate the connection of Internet voice and data services across multiple devices using copper twisted-pair wires. The company is recognized for creating technology that complies with the G.shdsl/HDSL2 high-speed symmetric DSL specification, which allows for the efficient transmission of high-speed voice and data over a single pair of wires. Established in 1998, Excess Bandwidth is a privately held company that focuses on designing symmetrical digital subscriber line physical-layer chips and mixed signal semiconductors for communications processors. Through its innovative solutions, the company aims to enhance high-bandwidth communications.
BrightLink Networks
Series C in 2000
BrightLink Networks, Inc. is a manufacturer of optical network switching systems. The company begins the marketing and manufacturing of its intelligent optical network system.
Tavolo
Venture Round in 2000
Tavolo offers an online store that enables its users to find and buy products related to cooking. Tavolo was acquired by OurHouse in December 2000. It is based in San Rafael, California.
CyOptics, Inc. is engaged in the design, development, and marketing of Indium Phosphide (InP) optical chips and components, which are essential for access, metro, and long-haul communications systems. The company's product offerings include planar lightwave circuits (PLCs) tailored for optical networks utilized in telecommunications and defense sectors. Additionally, CyOptics produces various optical components such as transmitters, receivers, and modulators, which serve as critical technology enablers for manufacturers of optical sub-assemblies and modules. The company also provides contract design, foundry, and packaging services, alongside radio frequency and optical design, wafer fabrication, and automated assembly and testing services for both telecom and non-telecom applications. Founded in 1999 and headquartered in Breinigsville, Pennsylvania, CyOptics operates InP design and fabrication facilities in Lehigh Valley, a silicon PLC fabrication site in South Plainfield, New Jersey, and automated packaging and testing operations in Matamoros, Mexico.
BravoGifts.com is the first e-commerce site tailored exclusively to the needs of the business gift market. BravoGifts.com provides the highest levels of service to its customers through: selection - the widest selection of business gifts available anywhere; gift advice and services - advice and information on business gifts, gift searching, unique gift selection tools, and business gift etiquette; and convenience - everything is centralized in one easily accessible Internet location. The company boasts the broadest collection of brilliant business gifts from executive toys and gadgets, to golf and weekend getaways, theater and sports tickets, and gourmet foods.
Spot something off? Help us improve by flagging any incorrect or outdated information. Just email us at support@teaserclub.com. Your feedback is most welcome.