Cultivate

Houston-based medical device startup Prana Thoracic, Inc. is dedicated to developing solutions for early intervention in lung cancer. We are an experienced team of surgeons, engineers and entrepreneurs on a mission to tackle lung cancer; the #1 cancer killer in the US. The paradigm of screening, detection, and early intervention that has been deployed in other major cancers has so far eluded lung cancer. As a result, only 16% of lung cancers are found at an early stage and the current 5-year survival rate is < 20%. Recent changes to lung cancer screening guidelines have illuminated a path to improving outcomes in lung cancer. However, these advances rely on excising suspicious nodules and providing sufficient tissue for definitive diagnosis. We believe this is the missing piece of the puzzle, and physicians need a new generation of surgical oncology tools for lung cancer. Prana Thoracic plans to revolutionize the early diagnosis and treatment of lung cancer by making it easier and less invasive to deal with the rapidly growing number of early suspicious lung nodules; ensuring that we do not miss the window of opportunity to intervene early.

Nanochon is focused on creating innovative implantable medical devices designed to address cartilage damage in joints. Utilizing advanced 3D printing techniques and a unique nanomaterial, the company aims to develop solutions that not only replace lost and damaged cartilage but also promote the growth of new tissue. This approach allows medical practitioners to access cost-effective and on-demand devices that enhance treatment outcomes, particularly for young and active patients suffering from knee injuries and diseases. Through its technology, Nanochon seeks to improve the overall quality of care in orthopedics.

Nanochon is focused on creating innovative implantable medical devices designed to address cartilage damage in joints. Utilizing advanced 3D printing techniques and a unique nanomaterial, the company aims to develop solutions that not only replace lost and damaged cartilage but also promote the growth of new tissue. This approach allows medical practitioners to access cost-effective and on-demand devices that enhance treatment outcomes, particularly for young and active patients suffering from knee injuries and diseases. Through its technology, Nanochon seeks to improve the overall quality of care in orthopedics.

Virtual Incision is focused on developing innovative surgical solutions, specifically through its miniaturized robotic support device designed for colon resection. The company's flagship product, the MIRA (Miniaturized In vivo Robotic Assistant) Platform, is a pioneering device that aims to streamline surgical procedures by allowing for quick setup in the operating room without the need for heavy equipment. This technology is intended to assist surgeons in improving clinical outcomes while also addressing healthcare costs. Virtual Incision's approach represents a significant advancement in robotic-assisted surgery, with plans for future applications beyond colon resection.

SentiAR, Inc. is a digital health company based in St. Louis, Missouri, specializing in 3D augmented reality solutions for interventional medical procedures. Founded in 2017 as a spin-off from Washington University, SentiAR has developed a platform that offers real-time holographic visualization of patients' anatomical structures and catheter locations. This technology integrates data from CT, MRI, and real-time mapping systems to create a controllable 3D holographic interface. The platform aims to enhance the delivery of care by allowing clinicians to visualize complex cardiac anatomy directly over the patient, thereby improving the treatment of cardiac arrhythmias during catheterization procedures. SentiAR is in the process of preparing its platform for submission to the FDA.

Shoulder Innovations is a medical device company that has developed inset glenoid fixation technology, creating the most robust and stable glenoid platform in the industry. The company's Total Shoulder Replacement System addresses the most significant issue in shoulder arthroplasty: unreliable fixation of the glenoid implant. It also leverages this technology to create simple surgical instrumentation, which reduces operative time and cost. Shoulder Innovations designs and commercializes innovative products that demonstrate the potential for improved patient care and reduced overall cost to the healthcare system. Published results show Shoulder Innovations’ solution provides greater post-surgical implant stability, addressing the leading cause of revision surgery.

SpinTech MRI has developed an innovative MRI imaging software platform designed to significantly reduce the time required for brain imaging while improving the visualization, quantification, and automatic detection of crucial biomarkers for diagnosing neurological conditions such as traumatic brain injury, dementia, Parkinson's disease, multiple sclerosis, and stroke. The platform is compatible with virtually any MRI machine, providing standardized high-quality images and facilitating the detection of microbleeds and quantification of neuromelanin content. By translating advanced research techniques into practical clinical applications, SpinTech MRI aims to enhance patient outcomes and offer cost-effective solutions that maximize the return on investment for imaging equipment, making advanced imaging technology accessible to a broader range of patients suffering from neurological diseases.

Strados Labs is a medical technology company that innovates respiratory monitoring using smart biosensors and artificial intelligence. The company specializes in advancing respiratory health management using clinical-grade biosensors and intelligent software. It connects people with real-time respiratory monitoring using a wearable device and connected mobile platform so they can quantify their health and make more informed decisions. The company was founded in 2016 and is headquartered in Philadelphia, Pennsylvania.

Deepstash operates a knowledge-based platform that focuses on delivering curated, bite-sized ideas extracted from a variety of online sources, including articles, videos, and podcasts. The platform is designed to help users navigate the overwhelming amount of information available on the internet by allowing them to save, organize, and share insights that resonate with them. Users can explore content aimed at enhancing their skills, productivity, and overall well-being. With a passionate community dedicated to uncovering meaningful insights, Deepstash emphasizes the importance of ideas as building blocks for personal and societal improvement. The Deepstash app is accessible on both mobile platforms and the web, making it convenient for users to engage with content that matters to them anytime and anywhere.

Embody, Inc. is a regenerative medicine company based in Norfolk, Virginia, dedicated to developing and commercializing implantable medical devices aimed at soft tissue restoration and regeneration. Founded in 2014, the company specializes in biomaterial design and bio-fabrication, focusing on collagen-based microfibers for tendon and ligament repair. Its innovative products are designed to meet the needs of warfighters, athletes, and individuals with sports injuries, utilizing a precision medicine approach to replicate the biological and biomechanical properties of native tissue. The goal of Embody is to enhance the quality of life for patients by restoring their pre-injury performance through effective healing solutions.

Genesis Software Innovations develops innovative and integrated software tools focused around surgical centers in the orthopedic space. The company's vision is to create great software tools that give medical professionals the information they need to produce repeatedly excellent, surgical results.

Magnesim Development Company, LLC (MDC) is a medical device development company delivering devices of a breakthrough resorbable metal alloy technology combining the strength and handling properties of metal with complete absorption for application in sports medicine orthopedics. Why is this important? Existing materials available for surgical repair marginally meet current surgical demands. Unsolved problems remain (delayed or lack of resorption, loose bodies, cyst formation, mechanical failure, post-operative imaging, etc) in surgical repair of soft tissue injuries (including knee, shoulder, and lower extremities). Occurrence of soft tissue, sports injury related medical events continue to grow as patients remain active longer, and expectations for return to activity increase. With more natural absorption, there remains potential for a bone growth stimulative effect, further enabling the return to activity and lifestyle.

SpinTech MRI has developed an innovative MRI imaging software platform designed to significantly reduce the time required for brain imaging while improving the visualization, quantification, and automatic detection of crucial biomarkers for diagnosing neurological conditions such as traumatic brain injury, dementia, Parkinson's disease, multiple sclerosis, and stroke. The platform is compatible with virtually any MRI machine, providing standardized high-quality images and facilitating the detection of microbleeds and quantification of neuromelanin content. By translating advanced research techniques into practical clinical applications, SpinTech MRI aims to enhance patient outcomes and offer cost-effective solutions that maximize the return on investment for imaging equipment, making advanced imaging technology accessible to a broader range of patients suffering from neurological diseases.

Medical Ingenuities, LLC is a medical device company based in Wheaton, Illinois, specializing in solutions that enhance patient care and healthcare systems. The company has developed the PH Band, a radial artery occlusion device that facilitates achieving and confirming hemostasis while providing real-time feedback on radial artery patency. This device is designed to assist medical personnel in monitoring blood flow after trans-radial procedures, thereby reducing the risk of complications associated with artery occlusion. The PH Band streamlines the workflow for healthcare providers and optimizes patient outcomes through its innovative design and functionality.

Shoulder Innovations is a medical device company that has developed inset glenoid fixation technology, creating the most robust and stable glenoid platform in the industry. The company's Total Shoulder Replacement System addresses the most significant issue in shoulder arthroplasty: unreliable fixation of the glenoid implant. It also leverages this technology to create simple surgical instrumentation, which reduces operative time and cost. Shoulder Innovations designs and commercializes innovative products that demonstrate the potential for improved patient care and reduced overall cost to the healthcare system. Published results show Shoulder Innovations’ solution provides greater post-surgical implant stability, addressing the leading cause of revision surgery.

Shoulder Innovations is a medical device company that has developed inset glenoid fixation technology, creating the most robust and stable glenoid platform in the industry. The company's Total Shoulder Replacement System addresses the most significant issue in shoulder arthroplasty: unreliable fixation of the glenoid implant. It also leverages this technology to create simple surgical instrumentation, which reduces operative time and cost. Shoulder Innovations designs and commercializes innovative products that demonstrate the potential for improved patient care and reduced overall cost to the healthcare system. Published results show Shoulder Innovations’ solution provides greater post-surgical implant stability, addressing the leading cause of revision surgery.