Technology Alliance Ventures

Alliance Technology Ventures is a venture capital firm based in Sarasota, Florida, founded in 1993 by Michael Henos. The firm specializes in investments within the semiconductor, communication components, and life sciences sectors, with a particular emphasis on novel biopharmaceuticals, diagnostics, and medical devices. Alliance Technology Ventures focuses its investments exclusively in the continental United States, primarily targeting opportunities in the Southeast. The firm invests between $0.5 million and $5 million in seed, early-stage, and select later-stage companies, often preferring to engage with new technologies prior to their commercial development. Additionally, Alliance Technology Ventures aims to take a board seat in its portfolio companies and typically seeks to be the lead investor, although it is open to forming syndicates with other investors.

Michael Henos

Founder and Managing General Partner

44 past transactions

Bagan Innovation Technology

Series A in 2017
Founded in 2012, Bagan Innovation Technology is a software company based in Yangon, Myanmar. It develops utility software and platforms, including an e-book delivery service, Burmese language mobile keyboards with speech recognition, social listening tools for businesses, and a social commerce chatbot. The company also operates an astrologer marketplace.

Crescent Biopharma

Series C in 2009
GlycoMimetics, Inc. is a clinical-stage biotechnology company dedicated to the discovery and development of innovative glycomimetic drugs aimed at addressing significant unmet medical needs associated with diseases influenced by carbohydrate biology. The company’s lead drug candidate, rivipansel, is a pan-selectin antagonist that has completed Phase III clinical trials for treating vaso-occlusive crises in sickle cell disease. Additionally, GlycoMimetics is developing uproleselan, an E-selectin inhibitor that is being tested in combination with chemotherapy for acute myeloid leukemia (AML) and in a Phase III trial for relapsed/refractory AML. The company also offers GMI-1359, which targets E-selectin and a chemokine receptor, having completed Phase I clinical trials, and is involved in developing other candidates, including GMI-1687 and Galectin-3. GlycoMimetics has established research collaborations, including an agreement with the National Cancer Institute and a partnership with Apollomics for the commercialization of uproleselan and GMI-1687. Founded in 2003, the company is headquartered in Rockville, Maryland.

SecureWorks

Series C in 2009
SecureWorks specializes in managed security services, offering network and IT security solutions. Recognized by Gartner as a leader in its Magic Quadrant for MSSPs, SecureWorks' platform combines SIEM with applied research and GIAC-certified experts to protect clients from cyber threats.

Apieron

Series D in 2009
Apieron is a medical technology company that specializes in developing non-invasive monitoring devices for asthma management. The company's flagship product measures exhaled nitric oxide (eNO), a biomarker associated with airway inflammation, providing valuable insights for the management of asthmatic conditions. Currently, Apieron's device has received clearance from the FDA but is restricted for use within a physician's office setting. By offering a reliable method for tracking asthma-related metrics, Apieron aims to enhance patient care and support healthcare providers in effectively managing respiratory health.

Garnet Biotherapeutics

Series A in 2009
Garnet BioTherapeutics is a clinical stage, venture-backed cell therapy company focused on dermal-based regenerative therapy.

Ziptronix

Venture Round in 2008
Ziptronix specializes in semiconductor integration technologies for the electronics industry. It offers solutions such as chip stacking and three-dimensional integrated circuits, enabling manufacturers of MEMS and RF devices to enhance interconnect density and system performance.

Ziptronix

Series D in 2007
Ziptronix specializes in semiconductor integration technologies for the electronics industry. It offers solutions such as chip stacking and three-dimensional integrated circuits, enabling manufacturers of MEMS and RF devices to enhance interconnect density and system performance.

Xytrans

Series E in 2006
Xytrans designs and manufactures high-frequency transceivers and outdoor units for global leaders in wireless broadband communications.

Crescent Biopharma

Series B in 2006
GlycoMimetics, Inc. is a clinical-stage biotechnology company dedicated to the discovery and development of innovative glycomimetic drugs aimed at addressing significant unmet medical needs associated with diseases influenced by carbohydrate biology. The company’s lead drug candidate, rivipansel, is a pan-selectin antagonist that has completed Phase III clinical trials for treating vaso-occlusive crises in sickle cell disease. Additionally, GlycoMimetics is developing uproleselan, an E-selectin inhibitor that is being tested in combination with chemotherapy for acute myeloid leukemia (AML) and in a Phase III trial for relapsed/refractory AML. The company also offers GMI-1359, which targets E-selectin and a chemokine receptor, having completed Phase I clinical trials, and is involved in developing other candidates, including GMI-1687 and Galectin-3. GlycoMimetics has established research collaborations, including an agreement with the National Cancer Institute and a partnership with Apollomics for the commercialization of uproleselan and GMI-1687. Founded in 2003, the company is headquartered in Rockville, Maryland.

Ziptronix

Series C in 2005
Ziptronix specializes in semiconductor integration technologies for the electronics industry. It offers solutions such as chip stacking and three-dimensional integrated circuits, enabling manufacturers of MEMS and RF devices to enhance interconnect density and system performance.

Bay Microsystems

Series D in 2005
Bay Microsystems, Inc. is a technology company that specializes in designing and developing advanced network solutions, including network architectures, systems, software, and integrated circuits. Founded in 1998 and headquartered in San Jose, California, with an office in Germantown, Maryland, the company offers a range of products such as the ABEx network appliance, which supports various networking protocols like synchronous optical networking and multiprotocol label switching. Additionally, Bay Microsystems develops a suite of network processors, including Chesapeake, Montego, and Biscayne, which enhance packet processing and traffic management capabilities. The company also provides the Lighthouse Tool Suite, a development platform for network processor-based equipment, and BayPort, a demonstration platform for evaluating their processors. By bridging the gap between enterprises and cloud storage systems, Bay Microsystems enables businesses with geo-diverse locations to effectively manage and utilize their distributed data assets.

Genoptix

Series C in 2004
Genoptix, Inc. is a specialized provider of oncology diagnostics services, focusing on delivering comprehensive testing solutions for hematologic malignancies and solid tumors. The company offers a variety of services, including customizable clinical trial support, custom assay development, and companion diagnostics. Its diagnostic capabilities encompass chromogenic and fluorescent immunohistochemistry, cytogenetics, flow cytometry, and a range of molecular testing platforms. Genoptix performs specialty assays to aid in patient diagnosis, treatment stratification, and disease monitoring, while also providing professional services for study data interpretation and endpoint adjudication. The company collaborates with community oncologists and pathologists to enhance molecular profiling in oncology and has established a strategic alliance with Bionano Genomics. Founded in 1999 and headquartered in Carlsbad, California, Genoptix is committed to advancing cancer diagnostics and improving patient outcomes through innovative testing solutions.

Crescent Biopharma

Series A in 2004
GlycoMimetics, Inc. is a clinical-stage biotechnology company dedicated to the discovery and development of innovative glycomimetic drugs aimed at addressing significant unmet medical needs associated with diseases influenced by carbohydrate biology. The company’s lead drug candidate, rivipansel, is a pan-selectin antagonist that has completed Phase III clinical trials for treating vaso-occlusive crises in sickle cell disease. Additionally, GlycoMimetics is developing uproleselan, an E-selectin inhibitor that is being tested in combination with chemotherapy for acute myeloid leukemia (AML) and in a Phase III trial for relapsed/refractory AML. The company also offers GMI-1359, which targets E-selectin and a chemokine receptor, having completed Phase I clinical trials, and is involved in developing other candidates, including GMI-1687 and Galectin-3. GlycoMimetics has established research collaborations, including an agreement with the National Cancer Institute and a partnership with Apollomics for the commercialization of uproleselan and GMI-1687. Founded in 2003, the company is headquartered in Rockville, Maryland.

OmniGuide

Series C in 2004
OmniGuide designs and manufactures compact CO₂ laser systems that deliver precise cutting, ablation, and coagulation with minimal thermal damage to surrounding tissue. The company’s Beampath platform integrates optical scalpels and advanced energy tools that are cleared for use in the United States and CE‑marked for Europe. By combining electrically silent operation with high‑resolution targeting, OmniGuide’s instruments enhance surgical accuracy and control across minimally invasive procedures, including laparoscopy and robotic‑assisted surgery. The firm focuses on preserving healthy tissue, improving clinical outcomes, and expanding the reach of minimally invasive techniques.

SyChip

Series D in 2004
SyChip Inc. specializes in the design, development, and marketing of Radio Frequency Integrated Circuits (RFIC) and Chip Scale Modules (CSM) tailored for the wireless Internet appliance market. The company is committed to creating highly integrated RF modules characterized by proprietary integration techniques, modular architectures, and low-loss silicon technologies. These innovations enhance the predictability and simulation of SyChip's RF designs, leading to reduced time-to-market while simultaneously improving performance and reliability. Through its advancements in RF technology, SyChip aims to meet the evolving needs of the wireless communication sector.

Nitronex

Series C in 2004
Nitronex is a company specializing in the development and manufacturing of gallium nitride-on-silicon (GaN-on-Si) RF power devices. Founded in 1999 by graduates from North Carolina State University's wide bandgap program, the company is headquartered in Durham, North Carolina. Nitronex is recognized as a global leader in high-performance GaN-on-Si RF power devices, holding 21 patents with an additional 17 pending. The company's products are primarily aimed at wireless communications, solid-state lighting, and data storage applications, with a focus on wireless infrastructure, broadband, and military markets. Through its innovative technology, Nitronex provides RF power transistors that enhance the performance and efficiency of various electronic systems.

Genoptix

Series B in 2003
Genoptix, Inc. is a specialized provider of oncology diagnostics services, focusing on delivering comprehensive testing solutions for hematologic malignancies and solid tumors. The company offers a variety of services, including customizable clinical trial support, custom assay development, and companion diagnostics. Its diagnostic capabilities encompass chromogenic and fluorescent immunohistochemistry, cytogenetics, flow cytometry, and a range of molecular testing platforms. Genoptix performs specialty assays to aid in patient diagnosis, treatment stratification, and disease monitoring, while also providing professional services for study data interpretation and endpoint adjudication. The company collaborates with community oncologists and pathologists to enhance molecular profiling in oncology and has established a strategic alliance with Bionano Genomics. Founded in 1999 and headquartered in Carlsbad, California, Genoptix is committed to advancing cancer diagnostics and improving patient outcomes through innovative testing solutions.

SyChip

Series C in 2003
SyChip Inc. specializes in the design, development, and marketing of Radio Frequency Integrated Circuits (RFIC) and Chip Scale Modules (CSM) tailored for the wireless Internet appliance market. The company is committed to creating highly integrated RF modules characterized by proprietary integration techniques, modular architectures, and low-loss silicon technologies. These innovations enhance the predictability and simulation of SyChip's RF designs, leading to reduced time-to-market while simultaneously improving performance and reliability. Through its advancements in RF technology, SyChip aims to meet the evolving needs of the wireless communication sector.

Nitronex

Series C in 2003
Nitronex is a company specializing in the development and manufacturing of gallium nitride-on-silicon (GaN-on-Si) RF power devices. Founded in 1999 by graduates from North Carolina State University's wide bandgap program, the company is headquartered in Durham, North Carolina. Nitronex is recognized as a global leader in high-performance GaN-on-Si RF power devices, holding 21 patents with an additional 17 pending. The company's products are primarily aimed at wireless communications, solid-state lighting, and data storage applications, with a focus on wireless infrastructure, broadband, and military markets. Through its innovative technology, Nitronex provides RF power transistors that enhance the performance and efficiency of various electronic systems.

Crescent Biopharma

Series A in 2003
GlycoMimetics, Inc. is a clinical-stage biotechnology company dedicated to the discovery and development of innovative glycomimetic drugs aimed at addressing significant unmet medical needs associated with diseases influenced by carbohydrate biology. The company’s lead drug candidate, rivipansel, is a pan-selectin antagonist that has completed Phase III clinical trials for treating vaso-occlusive crises in sickle cell disease. Additionally, GlycoMimetics is developing uproleselan, an E-selectin inhibitor that is being tested in combination with chemotherapy for acute myeloid leukemia (AML) and in a Phase III trial for relapsed/refractory AML. The company also offers GMI-1359, which targets E-selectin and a chemokine receptor, having completed Phase I clinical trials, and is involved in developing other candidates, including GMI-1687 and Galectin-3. GlycoMimetics has established research collaborations, including an agreement with the National Cancer Institute and a partnership with Apollomics for the commercialization of uproleselan and GMI-1687. Founded in 2003, the company is headquartered in Rockville, Maryland.

Apieron

Series A in 2003
Apieron is a medical technology company that specializes in developing non-invasive monitoring devices for asthma management. The company's flagship product measures exhaled nitric oxide (eNO), a biomarker associated with airway inflammation, providing valuable insights for the management of asthmatic conditions. Currently, Apieron's device has received clearance from the FDA but is restricted for use within a physician's office setting. By offering a reliable method for tracking asthma-related metrics, Apieron aims to enhance patient care and support healthcare providers in effectively managing respiratory health.

Sensys Medical

Series D in 2002
Sensys Medical develops a non-invasive blood glucose monitor that used near-infrared diffuse reflectance spectroscopy.

Xtreme Spectrum

Series C in 2002
XtremeSpectrum is a developer of ultrawideband (UWB) impulse radio -- a wireless technology for products such as set-top boxes, digital displays, camcorders, DVD players, digital video recorders and digital cameras.

Xytrans

Series B in 2002
Xytrans designs and manufactures high-frequency transceivers and outdoor units for global leaders in wireless broadband communications.

OmniGuide

Series B in 2002
OmniGuide designs and manufactures compact CO₂ laser systems that deliver precise cutting, ablation, and coagulation with minimal thermal damage to surrounding tissue. The company’s Beampath platform integrates optical scalpels and advanced energy tools that are cleared for use in the United States and CE‑marked for Europe. By combining electrically silent operation with high‑resolution targeting, OmniGuide’s instruments enhance surgical accuracy and control across minimally invasive procedures, including laparoscopy and robotic‑assisted surgery. The firm focuses on preserving healthy tissue, improving clinical outcomes, and expanding the reach of minimally invasive techniques.

SyChip

Series B in 2002
SyChip Inc. specializes in the design, development, and marketing of Radio Frequency Integrated Circuits (RFIC) and Chip Scale Modules (CSM) tailored for the wireless Internet appliance market. The company is committed to creating highly integrated RF modules characterized by proprietary integration techniques, modular architectures, and low-loss silicon technologies. These innovations enhance the predictability and simulation of SyChip's RF designs, leading to reduced time-to-market while simultaneously improving performance and reliability. Through its advancements in RF technology, SyChip aims to meet the evolving needs of the wireless communication sector.

Inhibitex

Venture Round in 2002
Inhibitex is a biotechnology company that specializes in the development of antibody-based products aimed at preventing and treating bacterial and fungal infections. The company is particularly focused on creating small molecule antiviral compounds, with specific attention to therapies for shingles, also known as herpes zoster, and chronic hepatitis C infections. Through its innovative approach, Inhibitex seeks to address significant medical needs in the realm of infectious diseases.

Cygnal Integrated Products

Series C in 2002
The Cygnal Group specializes in designing, manufacturing, and marketing field-programmable, mixed-signal System-on-Chip products and associated support tools. The company focuses on integrating advanced analog, high-speed digital, and FLASH memory functions into a single device, offering users enhanced component integration, design flexibility, and improved system performance. Cygnal's product offerings include analog-intensive 8-bit microcontrollers, which are utilized across diverse applications such as industrial automation, automotive sensors, medical instrumentation, and electronic test equipment. The company's global sales strategy relies on a network of field application engineers and manufacturer representatives, ensuring comprehensive support across various markets, including communications systems, industrial equipment, and consumer products.

SyChip

Series A in 2001
SyChip Inc. specializes in the design, development, and marketing of Radio Frequency Integrated Circuits (RFIC) and Chip Scale Modules (CSM) tailored for the wireless Internet appliance market. The company is committed to creating highly integrated RF modules characterized by proprietary integration techniques, modular architectures, and low-loss silicon technologies. These innovations enhance the predictability and simulation of SyChip's RF designs, leading to reduced time-to-market while simultaneously improving performance and reliability. Through its advancements in RF technology, SyChip aims to meet the evolving needs of the wireless communication sector.

Nitronex

Series B in 2001
Nitronex is a company specializing in the development and manufacturing of gallium nitride-on-silicon (GaN-on-Si) RF power devices. Founded in 1999 by graduates from North Carolina State University's wide bandgap program, the company is headquartered in Durham, North Carolina. Nitronex is recognized as a global leader in high-performance GaN-on-Si RF power devices, holding 21 patents with an additional 17 pending. The company's products are primarily aimed at wireless communications, solid-state lighting, and data storage applications, with a focus on wireless infrastructure, broadband, and military markets. Through its innovative technology, Nitronex provides RF power transistors that enhance the performance and efficiency of various electronic systems.

Xytrans

Series A in 2001
Xytrans designs and manufactures high-frequency transceivers and outdoor units for global leaders in wireless broadband communications.

SecureWorks

Series B in 2000
SecureWorks specializes in managed security services, offering network and IT security solutions. Recognized by Gartner as a leader in its Magic Quadrant for MSSPs, SecureWorks' platform combines SIEM with applied research and GIAC-certified experts to protect clients from cyber threats.

Helios Health

Venture Round in 2000
Helios Health is a provider of a healthcare service platform that focuses on delivering accurate and timely health information and services. The company's platform offers high-impact access to essential healthcare resources through e-stations, facilitating comprehensive patient care that encompasses diagnosis, treatment, and follow-up services. By leveraging web-based technology, Helios Health aims to enhance the healthcare experience for users, ensuring they receive the necessary information and support throughout their medical journeys.

Nitronex

Series A in 2000
Nitronex is a company specializing in the development and manufacturing of gallium nitride-on-silicon (GaN-on-Si) RF power devices. Founded in 1999 by graduates from North Carolina State University's wide bandgap program, the company is headquartered in Durham, North Carolina. Nitronex is recognized as a global leader in high-performance GaN-on-Si RF power devices, holding 21 patents with an additional 17 pending. The company's products are primarily aimed at wireless communications, solid-state lighting, and data storage applications, with a focus on wireless infrastructure, broadband, and military markets. Through its innovative technology, Nitronex provides RF power transistors that enhance the performance and efficiency of various electronic systems.

Ziptronix

Series A in 2000
Ziptronix specializes in semiconductor integration technologies for the electronics industry. It offers solutions such as chip stacking and three-dimensional integrated circuits, enabling manufacturers of MEMS and RF devices to enhance interconnect density and system performance.

ZapMedia

Venture Round in 2000
ZAPmedia is a boutique publisher specializing in the creation and distribution of books, art, and web content. The company focuses on delivering high-quality, curated materials that cater to a niche audience. By emphasizing artistic expression and literary craftsmanship, ZAPmedia aims to provide unique and engaging content that stands out in the marketplace.

Synchrologic

Private Equity Round in 2000
Synchrologic is a developer of mobile infrastructure solutions focused on data synchronization. The company specializes in extending existing corporate infrastructure to support mobile and remote staff, enabling access to enterprise applications, files, email, personal information management (PIM) data, intranet sites, and web content. Synchrologic's comprehensive software solutions are designed to facilitate connectivity for various users, including employees, customers, partners, and suppliers, thereby enhancing productivity and collaboration in mobile environments.

ValuBond

Series B in 2000
ValuBond offers a comprehensive fixed-income solution tailored for brokerages and financial advisors. The company operates an online platform that provides extensive fixed-income information and trading products, including access to bonds and municipal bonds. ValuBond's offerings include a broker workstation and various trading technologies designed to meet the diverse needs of financial services organizations. Additionally, the Bond Express Private Label solution allows firms to integrate ValuBond's services into their internal or public websites. Through partnerships with numerous securities firms, ValuBond provides a robust secondary marketplace and access to a wide inventory, catering to millions of retail customers both online and offline.

SecureWorks

Series A in 2000
SecureWorks specializes in managed security services, offering network and IT security solutions. Recognized by Gartner as a leader in its Magic Quadrant for MSSPs, SecureWorks' platform combines SIEM with applied research and GIAC-certified experts to protect clients from cyber threats.

MindLever Corporation

Series A in 1999
MindLever.com provides an integrated e-learning environment over the internet.

Eprise

Venture Round in 1999
Eprise offers software solutions and services enabling businesses to efficiently manage and control web content.

Home Wireless Networks

Series B in 1998
Home Wireless Networks specializes in providing wireless telephony and data networking solutions tailored for residential and small office/home office environments. The company focuses on enabling seamless connectivity between various devices, including personal computers, telephones, and fax machines, without the need for physical wiring. By leveraging advanced technology, Home Wireless Networks aims to enhance the convenience and efficiency of home and small office communication setups.

VeriFiber

Series A in 1998
Founded by Lee Thompson and Tim Richardson in November 1996. Acquired by Bandwidth9, Inc. in August of 2000. Spin-out by Lee Thompson in March of 2002.
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