Psilos Group

Psilos Group, established in 1998 and headquartered in New York, is a private equity firm specializing in venture capital investments in healthcare and technology sectors across the United States. The firm identifies and invests in companies with transformative ideas, strong management teams, and broad market applicability, aiming to create enduring market value and improve the healthcare system. Psilos seeks to be the lead investor, providing significant positive impact and strategic guidance to its portfolio companies, and fosters strong partnerships with management teams.

Albert S. Waxman

Senior Managing Member and CEO

37 past transactions

PatientSafe Solutions

Venture Round in 2017
PatientSafe Solutions, headquartered in San Diego, California, specializes in smart point-of-care mobile solutions aimed at transforming healthcare delivery. Its flagship product, the PatientTouch System, enhances care team productivity and patient safety by consolidating clinical workflows into a single, portable device. The innovative platform integrates communication, workflow management, and real-time access to electronic medical records, facilitating effective collaboration among clinicians. Features such as Positive Patient Identification, customizable care interventions, and real-time alerting capabilities support critical processes like medication administration and specimen collection. By leveraging advanced technology, PatientSafe Solutions enables healthcare providers to improve safety, increase efficiency, and reduce operational costs, positioning itself as a leader in accountable care innovation.

Gamma Medica

Series B in 2014
Gamma Medica, Inc. specializes in digital molecular imaging devices focused on early breast cancer detection. The company is recognized for its LumaGEM® MBI System, the first commercially available, FDA-cleared imaging system that employs cadmium zinc telluride (CZT) technology. This innovative planar, dual-head, fully solid-state system is designed to identify millimeter-sized breast cancers that are often overlooked by traditional mammography, particularly in women with dense breast tissue. In addition to the LumaGEM system, Gamma Medica offers a range of imaging technologies, including digital X-ray mammography, tomography, 3D mammography, and ultrasound systems, all aimed at enhancing screening capabilities for dense breast tissue and promoting early-stage cancer prevention.

PatientSafe Solutions

Series C in 2013
PatientSafe Solutions, headquartered in San Diego, California, specializes in smart point-of-care mobile solutions aimed at transforming healthcare delivery. Its flagship product, the PatientTouch System, enhances care team productivity and patient safety by consolidating clinical workflows into a single, portable device. The innovative platform integrates communication, workflow management, and real-time access to electronic medical records, facilitating effective collaboration among clinicians. Features such as Positive Patient Identification, customizable care interventions, and real-time alerting capabilities support critical processes like medication administration and specimen collection. By leveraging advanced technology, PatientSafe Solutions enables healthcare providers to improve safety, increase efficiency, and reduce operational costs, positioning itself as a leader in accountable care innovation.

Gamma Medica

Series A in 2013
Gamma Medica, Inc. specializes in digital molecular imaging devices focused on early breast cancer detection. The company is recognized for its LumaGEM® MBI System, the first commercially available, FDA-cleared imaging system that employs cadmium zinc telluride (CZT) technology. This innovative planar, dual-head, fully solid-state system is designed to identify millimeter-sized breast cancers that are often overlooked by traditional mammography, particularly in women with dense breast tissue. In addition to the LumaGEM system, Gamma Medica offers a range of imaging technologies, including digital X-ray mammography, tomography, 3D mammography, and ultrasound systems, all aimed at enhancing screening capabilities for dense breast tissue and promoting early-stage cancer prevention.

PatientSafe Solutions

Series C in 2013
PatientSafe Solutions, headquartered in San Diego, California, specializes in smart point-of-care mobile solutions aimed at transforming healthcare delivery. Its flagship product, the PatientTouch System, enhances care team productivity and patient safety by consolidating clinical workflows into a single, portable device. The innovative platform integrates communication, workflow management, and real-time access to electronic medical records, facilitating effective collaboration among clinicians. Features such as Positive Patient Identification, customizable care interventions, and real-time alerting capabilities support critical processes like medication administration and specimen collection. By leveraging advanced technology, PatientSafe Solutions enables healthcare providers to improve safety, increase efficiency, and reduce operational costs, positioning itself as a leader in accountable care innovation.

SeeChange Health

Series C in 2013
We provide the information, tools, and technology to help employees take control of their health, while companies take control of their health expenses. Whether you’re looking for flexible, self-administered health plans or customizable engagement software, our SeeChange Health Solutions make it easy to administer value-based benefits within your company.

SeeChange Health

Series B in 2011
We provide the information, tools, and technology to help employees take control of their health, while companies take control of their health expenses. Whether you’re looking for flexible, self-administered health plans or customizable engagement software, our SeeChange Health Solutions make it easy to administer value-based benefits within your company.

PatientSafe Solutions

Series B in 2010
PatientSafe Solutions, headquartered in San Diego, California, specializes in smart point-of-care mobile solutions aimed at transforming healthcare delivery. Its flagship product, the PatientTouch System, enhances care team productivity and patient safety by consolidating clinical workflows into a single, portable device. The innovative platform integrates communication, workflow management, and real-time access to electronic medical records, facilitating effective collaboration among clinicians. Features such as Positive Patient Identification, customizable care interventions, and real-time alerting capabilities support critical processes like medication administration and specimen collection. By leveraging advanced technology, PatientSafe Solutions enables healthcare providers to improve safety, increase efficiency, and reduce operational costs, positioning itself as a leader in accountable care innovation.

Gamma Medica-Ideas

Series A in 2009
Gamma Medica-Ideas (GM-I) develops novel technologies to markets that improve patient health through early diagnosis of disease, improved patient treatment and by enabling new drug discovery. GM-I also develops medical devices and techniques to support molecular imaging of living subjects, targeted at the pharmaceutical pre-clinical research and clinical diagnostic markets. GM-I is dedicated to developing cutting-edge, fully digital imaging systems using the most advanced solid-state technologies.

SeeChange Health

Series A in 2009
We provide the information, tools, and technology to help employees take control of their health, while companies take control of their health expenses. Whether you’re looking for flexible, self-administered health plans or customizable engagement software, our SeeChange Health Solutions make it easy to administer value-based benefits within your company.

VeraLight

Series C in 2008
VeraLight is a medical device company founded in October 2004, specializing in non-invasive screening for type 2 diabetes and pre-diabetes through its proprietary SCOUT DS system. The company aims to combat the global diabetes epidemic by promoting early detection, which can lead to timely interventions that prevent the onset of diabetes and mitigate its complications. VeraLight focuses on developing and acquiring innovative technologies, products, and services that align with its mission to improve diabetes management and patient outcomes.

OmniGuide

Series E in 2008
OmniGuide is a manufacturer specializing in advanced surgical tools that utilize CO2 laser technology to enhance precision in minimally invasive procedures. The company's Beampath CO2 laser energy system integrates cutting, ablation, and coagulation capabilities while minimizing thermal damage to surrounding healthy tissues. OmniGuide's products are designed to improve surgical outcomes and expand the possibilities of minimally invasive surgery through indication-specific instruments. By delivering energy in a precise and electrically silent manner, the company aims to enhance surgical accuracy and control, ultimately preserving healthy tissues during procedures. Committed to improving patient quality of life, OmniGuide also emphasizes exceptional customer service, ensuring that healthcare providers have access to innovative solutions that support safe and effective surgical practices.

HealthEdge

Venture Round in 2008
HealthEdge is a technology company that provides an integrated software platform designed for healthcare payors. Founded in December 2004 by Albert Waxman and Rob Gillette, HealthEdge specializes in delivering innovative solutions that help health insurers enhance operational efficiency, improve patient outcomes, and significantly lower administrative costs. The company's flagship product suite, HealthRules, is built on patented technology and can be deployed via the HealthEdge Cloud or on-premises. This platform encompasses various functionalities, including claims and benefits administration, care management, and business intelligence, enabling clients to adopt new business models and streamline processes within the healthcare delivery system. In 2012, HealthEdge expanded its offerings by acquiring Click4Care, which enhanced its capabilities in clinical care management. Headquartered in Burlington, Massachusetts, HealthEdge also has a research and development center in Powell, Ohio.

Mauna Kea Technologies

Series B in 2008
Mauna Kea Technologies, established in 2000 and based in Paris, France, specializes in developing and marketing medical devices for cancer and other disease diagnosis and treatment. Its core product, Cellvizio, is a real-time, cellular-level imaging platform used by physicians and researchers worldwide. This platform, based on confocal laser endomicroscopy, enables precise, in vivo visualization of tissues during standard procedures, aiding in early-stage pathology detection and informed therapeutic decisions. The company generates revenue through the sale of Cellvizio products and accessories, serving customers in Europe, the Middle East, Africa, the Americas, and Asia.

AngioScore

Series E in 2007
AngioScore Inc. is engaged in the development, manufacturing, and marketing of medical devices, specifically focusing on the AngioSculpt Scoring Balloon Catheter. This catheter is designed for use in both coronary and peripheral interventional markets, addressing the limitations commonly associated with traditional angioplasty balloon catheters. The AngioSculpt features a semi-compliant balloon combined with a unique nitinol scoring element, enhancing its effectiveness in endovascular therapy. The company's products are aimed at improving the treatment of cardiovascular and vascular diseases.

Extend Health

Series B in 2007
Extend Health specializes in offering defined contribution benefit and insurance programs tailored for employees and retirees in corporate America. The company focuses on assisting clients in selecting appropriate Medicare programs, facilitating the transition from traditional group benefits to individualized defined-contribution plans. This approach allows corporations to provide more personalized benefits to their workforce while empowering employees and retirees to make informed decisions about their healthcare options.

Click4Care

Series A in 2007
Click4Care, Inc. is a provider of medical management software designed to enhance healthcare delivery for payers, providers, and patients. Founded in 1999 and headquartered in Powell, Ohio, the company offers its flagship product, ThinkHealth, which automates workflows related to utilization management, disease management, and population health management. This software aims to enable health insurers to deliver seamless and differentiated services that improve care delivery and promote illness prevention.

PatientSafe Solutions

Series D in 2007
PatientSafe Solutions, headquartered in San Diego, California, specializes in smart point-of-care mobile solutions aimed at transforming healthcare delivery. Its flagship product, the PatientTouch System, enhances care team productivity and patient safety by consolidating clinical workflows into a single, portable device. The innovative platform integrates communication, workflow management, and real-time access to electronic medical records, facilitating effective collaboration among clinicians. Features such as Positive Patient Identification, customizable care interventions, and real-time alerting capabilities support critical processes like medication administration and specimen collection. By leveraging advanced technology, PatientSafe Solutions enables healthcare providers to improve safety, increase efficiency, and reduce operational costs, positioning itself as a leader in accountable care innovation.

Health Hero Networks

Series B in 2006
Health Hero Network, Inc. specializes in developing technology solutions for remote health monitoring and management, primarily aimed at enhancing communication between patients and healthcare providers. The company offers a comprehensive Health Buddy system that facilitates patient education and chronic condition monitoring, integrating various technologies and clinical information databases. Its services cater to a diverse clientele, including hospitals, health plans, government health organizations, disease management firms, and pharmaceutical companies involved in clinical trials. Founded in 1988 and based in Palo Alto, California, Health Hero Network operates as a subsidiary of Robert Bosch GMBH, focusing on delivering personalized health management programs that enable providers to effectively monitor patient health and make informed decisions.

VeraLight

Series B in 2006
VeraLight is a medical device company founded in October 2004, specializing in non-invasive screening for type 2 diabetes and pre-diabetes through its proprietary SCOUT DS system. The company aims to combat the global diabetes epidemic by promoting early detection, which can lead to timely interventions that prevent the onset of diabetes and mitigate its complications. VeraLight focuses on developing and acquiring innovative technologies, products, and services that align with its mission to improve diabetes management and patient outcomes.

AngioScore

Series D in 2006
AngioScore Inc. is engaged in the development, manufacturing, and marketing of medical devices, specifically focusing on the AngioSculpt Scoring Balloon Catheter. This catheter is designed for use in both coronary and peripheral interventional markets, addressing the limitations commonly associated with traditional angioplasty balloon catheters. The AngioSculpt features a semi-compliant balloon combined with a unique nitinol scoring element, enhancing its effectiveness in endovascular therapy. The company's products are aimed at improving the treatment of cardiovascular and vascular diseases.

Acuity Pharmaceuticals

Series B in 2004
Acuity Pharmaceuticals is a pharmaceutical company based in Philadelphia, Pennsylvania, established in 2007. It specializes in the treatment and prevention of ophthalmic diseases, particularly focusing on age-related macular degeneration (AMD) and diabetic retinopathy (DR). The company is developing small interfering RNA compounds aimed at addressing vision loss associated with these conditions. One of its key products, Cand5, is a clinical compound designed to inhibit vascular endothelial growth factor, thereby targeting adult vision loss. In June 2011, Acuity Pharmaceuticals was acquired by OPKO Health, enhancing its capabilities in the ophthalmic market.

AngioScore

Series B in 2004
AngioScore Inc. is engaged in the development, manufacturing, and marketing of medical devices, specifically focusing on the AngioSculpt Scoring Balloon Catheter. This catheter is designed for use in both coronary and peripheral interventional markets, addressing the limitations commonly associated with traditional angioplasty balloon catheters. The AngioSculpt features a semi-compliant balloon combined with a unique nitinol scoring element, enhancing its effectiveness in endovascular therapy. The company's products are aimed at improving the treatment of cardiovascular and vascular diseases.

InSound Medical

Series D in 2004
InSound Medical, Inc. is a privately held company located in Newark, California, specializing in the development and manufacture of advanced hearing solutions. The company is backed by prominent investors such as Johnson & Johnson, DeNovo Ventures, CMEA Ventures, and Psilos Group Managers, LLC. InSound Medical's flagship product is Lyric, an innovative invisible extended wear hearing device designed to provide users with a discreet and effective hearing solution.

deNovis

Series C in 2004
deNovis Inc. is a leading provider of advanced transaction processing and information management solutions for the health insurance and health care benefits administration industry. deNovis's highly innovative claims processing and data management software enables commercial and government health plans to reduce administrative costs, expand their range of products and services, increase speed-to-market of new products and enhance the quality of customer service. The company's flagship software product—eHD™—serves as the core administrative platform for health plans and is designed to deliver the sophistication necessary to meet both existing and emerging needs of commercial, Medicare and Medicaid healthcare benefits administrators. deNovis is also known for its technical innovations, including HICL™ technology, which allows complex healthcare transaction systems to be programmed by business analysts rather than computer programmers, using English language commands and the actual policies and business rules of the health plan. deNovis's customer roster includes large commercial insurers and the U. S. Department of Health and Human Services—the nation's largest purchaser of healthcare and a provider of healthcare benefits to almost 80 million Americans. The company's strategic alliance partners include IBM Corporation and Deloitte Consulting. deNovis enterprise solutions for health plans are available for installation at customer locations or can be delivered on an outsourced or remote-hosted basis. The company is privately held and is headquartered in Lexington, Massachusetts.

Cohesive Technologies

Series B in 2003
Cohesive Technologies Inc. designs, manufactures, and markets breakthrough liquid chromatography (LC) solutions for the drug discovery, pharmaceutical, contract research, and clinical diagnostic industries. The company has developed patented technologies and a wide range of chromatographic products designed to significantly improve productivity by accelerating the separation, purification, and analysis of molecules in bioanalysis. With a strong depth of knowledge in column chemistry, applications, engineering, software development, and quality management, Cohesive Technologies leads the industry in the research, development, and production of LC technologies that accelerate the pace of customers' drug discovery and development efforts.

Estech

Series B in 2003
Estech is a privately held medical device manufacturing and distribution company based in San Ramon, California. Founded in 1996 by Arthur and Raymond Bertolero, the company focuses on developing and marketing medical devices and disposables that facilitate both traditional and minimally invasive cardiac surgical procedures. Estech has established a global distribution network and is recognized for attracting skilled professionals in the medical device sector. The company's commitment to innovation and quality has enabled it to achieve sustained success in a competitive industry, reflecting the dedication of its team across all departments.

OneShield

Series C in 2002
OneShield, Inc. specializes in providing business software solutions to the global insurance industry, focusing on property, casualty, and general insurance. Its offerings include enterprise-class solutions for policy, billing, claims, and rating management, as well as tools for managing general agencies and third-party administrators. OneShield's Transaction Engine Service Layer is a cloud-hosted, As-A-Service platform that implements a collection of vendor-independent service-oriented architecture web services. The company also provides implementation, client support, training, and cloud services. With headquarters in Marlborough, Massachusetts, and offices in Australia, Canada, and India, OneShield serves clients across various insurance markets, aiming to automate and simplify core systems' complexities.

deNovis

Series B in 2001
deNovis Inc. is a leading provider of advanced transaction processing and information management solutions for the health insurance and health care benefits administration industry. deNovis's highly innovative claims processing and data management software enables commercial and government health plans to reduce administrative costs, expand their range of products and services, increase speed-to-market of new products and enhance the quality of customer service. The company's flagship software product—eHD™—serves as the core administrative platform for health plans and is designed to deliver the sophistication necessary to meet both existing and emerging needs of commercial, Medicare and Medicaid healthcare benefits administrators. deNovis is also known for its technical innovations, including HICL™ technology, which allows complex healthcare transaction systems to be programmed by business analysts rather than computer programmers, using English language commands and the actual policies and business rules of the health plan. deNovis's customer roster includes large commercial insurers and the U. S. Department of Health and Human Services—the nation's largest purchaser of healthcare and a provider of healthcare benefits to almost 80 million Americans. The company's strategic alliance partners include IBM Corporation and Deloitte Consulting. deNovis enterprise solutions for health plans are available for installation at customer locations or can be delivered on an outsourced or remote-hosted basis. The company is privately held and is headquartered in Lexington, Massachusetts.

MRxonline

Venture Round in 2001
They are an Internet Application Service Provider (ASP) offering a suite of web-based medical billing and compliance management services. MRxonline.com has developed key business-to-business alliances that allow us to deliver the first scalable, dedicated Internet medical billing application to third-party billing companies, large practices, PHO's, IPA's, payers and practice management organizations. This new approach to practice management provides cost-effective solutions such as coding compliance monitoring and reporting at a level that is generally unavailable to physician practices. By existing entirely as an Internet application, hardware and software capital investments as well as system maintenance costs are dramatically reduced thereby allowing the physician to focus on practicing medicine, not practice management.

eMotion

Venture Round in 2000
eMotion, Inc. specializes in providing hosted business applications designed to manage and distribute digital media assets and marketing content. The company offers digital asset management software that enables corporations, advertising agencies, and nonprofit organizations to develop, manage, and distribute various media types, including digital photos, videos, and audio files. Its solutions facilitate the distribution of marketing materials across multiple locations, catering to the needs of blue-chip companies, entertainment firms, and government agencies. eMotion's offerings include brand portals, marketing extranets, and digital asset libraries, allowing users to streamline their media management processes. Established in 2000 through the merger of Cinebase Software and Picture Networks International, eMotion is headquartered in San Francisco, California, with an additional office in Vienna, Virginia. The company has operated as a subsidiary of Artesia Technologies, Inc. since 2008.

Active Health Managment

Series A in 2000
ActiveHealth Management is a national leader in population health management and passionate about helping every person achieve his or her best health. They deliver personalized guidance through their analytics and insights, care management, health, lifestyle and wellness programs to help their customers improve quality of care, lower healthcare costs, and drive sustained member engagement and behavior change. ActiveHealth® collaborates with employers, health plans, governments and providers currently helping more than 20 million people live their healthiest lives. ActiveHealth Management is an independent subsidiary of Aetna (NYSE: AET)

Definity Health

Venture Round in 2000
Definity Health focuses on the development of programs and products to enhance the consumer health care experience. Definity Health develops solutions that educate patients to assist them to make decision in treatments. Definity Health is acquired by UnitedHealth Group. Definity Health was founded in 1998 and is based in Saint Louis Park, Minnesota.

Health Hero Network

Venture Round in 2000
Health Hero Network combines digital convenience with clinical expertise. They provide people with remote access to expert clinicians. They builts a platform that marries user-centric innovation with healthcare expertise and have embarked on the journey together. They provide health management programs delivering personalized daily monitoring, patient education, and information to care providers.

HealthAnswers Education

Series A in 2000
HealthAnswers Education is a specialized provider of sales training and medical education programs tailored for the pharmaceutical and biotechnology sectors. With a history spanning over 25 years, the company has successfully trained tens of thousands of sales professionals across various disease categories using a mix of live and virtual platforms. HealthAnswers collaborates with industry leaders to develop customized educational programs that address specific training needs, ensuring that the delivered content meets high standards of effectiveness and engagement. The company excels in providing clinical and product training, skill development, and Sales Force Effectiveness activities, including needs assessments and curriculum audits. By focusing on creative design and instructional methodologies, HealthAnswers Education aims to enhance the knowledge and skills of healthcare sales professionals and managers.

ClickThings

Venture Round in 2000
ClickThings

Health Hero Networks

Venture Round in 1998
Health Hero Network, Inc. specializes in developing technology solutions for remote health monitoring and management, primarily aimed at enhancing communication between patients and healthcare providers. The company offers a comprehensive Health Buddy system that facilitates patient education and chronic condition monitoring, integrating various technologies and clinical information databases. Its services cater to a diverse clientele, including hospitals, health plans, government health organizations, disease management firms, and pharmaceutical companies involved in clinical trials. Founded in 1988 and based in Palo Alto, California, Health Hero Network operates as a subsidiary of Robert Bosch GMBH, focusing on delivering personalized health management programs that enable providers to effectively monitor patient health and make informed decisions.
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