SDL Ventures

SelectION is a clinical-stage biopharmaceutical company focused on developing innovative peptide therapies for autoimmune diseases and certain cancer indications. The company utilizes a specialized technology platform that targets autoreactive, chronically activated T cells through the creation of selective peptide blockers for ion channels associated with these conditions. This approach aims to functionally inhibit and eliminate disease-related T cells while preserving the protective immune response. By optimizing target selectivity, SelectION seeks to develop therapeutics that offer significantly improved efficacy and safety profiles, ultimately providing healthcare institutions with effective treatment options for pain management and oncology.

Retrotope Inc. is a pharmaceutical company focused on developing therapeutics for degenerative diseases, particularly those affecting mitochondrial health. Founded in 2006 and based in Los Altos, California, Retrotope specializes in addressing conditions such as Parkinson's disease, Alzheimer's disease, mitochondrial myopathies, and retinopathies. The company is known for its drug RT001, which targets infantile neuroaxonal dystrophy, and it employs a unique drug platform that utilizes isotope effects to mitigate oxidative stress and cellular damage. Through several discovery and development programs, Retrotope aims to create innovative solutions for a range of neurological disorders, including Friedreich's ataxia, while also contributing to the broader understanding of metabolic processes related to these conditions.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

BridgeWave Communications, Inc. specializes in the design, manufacture, and marketing of microwave and millimeter wave backhaul and fronthaul systems for operators, carriers, service providers, governments, and private enterprises. The company's product offerings include the NAVIGATOR, a multi-gigabit all-outdoor licensed microwave radio system, and various Flex4G systems that deliver high-capacity, full-duplex data throughput. These solutions serve as fiber alternatives in applications such as mobile backhaul, mobile fronthaul, broadband/IP connectivity, disaster recovery, and video surveillance. BridgeWave's products are marketed through a network of authorized resellers, distributors, and system integrators globally. Founded in 1999 and headquartered in San Diego, California, BridgeWave operates as a subsidiary of REMEC Broadband Wireless Networks, LLC.

BridgeWave Communications, Inc. specializes in the design, manufacture, and marketing of microwave and millimeter wave backhaul and fronthaul systems for operators, carriers, service providers, governments, and private enterprises. The company's product offerings include the NAVIGATOR, a multi-gigabit all-outdoor licensed microwave radio system, and various Flex4G systems that deliver high-capacity, full-duplex data throughput. These solutions serve as fiber alternatives in applications such as mobile backhaul, mobile fronthaul, broadband/IP connectivity, disaster recovery, and video surveillance. BridgeWave's products are marketed through a network of authorized resellers, distributors, and system integrators globally. Founded in 1999 and headquartered in San Diego, California, BridgeWave operates as a subsidiary of REMEC Broadband Wireless Networks, LLC.

TRIA Beauty, Inc. specializes in developing and selling light-based medical devices designed for consumer use in skincare and beauty treatments. The company's primary offerings include a hand-held diode laser device for permanent hair removal, a Skin Perfecting Blue Light device targeting acne-causing bacteria, a Skin Rejuvenating Laser for anti-aging, and an Age-Defying Eye Wrinkle Correcting Laser aimed at reducing fine lines around the eyes. These products leverage advanced light technology, typically used in professional dermatological treatments, allowing users to achieve salon-quality results at home. TRIA Beauty markets its products through its e-commerce platform and various indirect sales channels, including television, retail locations, and physician offices. Founded in 2003 and headquartered in Dublin, California, TRIA Beauty serves customers across multiple countries, including the United States, Japan, and several European nations. The company previously operated under the name SpectraGenics, Inc. before rebranding in 2008.

TRIA Beauty, Inc. specializes in developing and selling light-based medical devices designed for consumer use in skincare and beauty treatments. The company's primary offerings include a hand-held diode laser device for permanent hair removal, a Skin Perfecting Blue Light device targeting acne-causing bacteria, a Skin Rejuvenating Laser for anti-aging, and an Age-Defying Eye Wrinkle Correcting Laser aimed at reducing fine lines around the eyes. These products leverage advanced light technology, typically used in professional dermatological treatments, allowing users to achieve salon-quality results at home. TRIA Beauty markets its products through its e-commerce platform and various indirect sales channels, including television, retail locations, and physician offices. Founded in 2003 and headquartered in Dublin, California, TRIA Beauty serves customers across multiple countries, including the United States, Japan, and several European nations. The company previously operated under the name SpectraGenics, Inc. before rebranding in 2008.

TRIA Beauty, Inc. specializes in developing and selling light-based medical devices designed for consumer use in skincare and beauty treatments. The company's primary offerings include a hand-held diode laser device for permanent hair removal, a Skin Perfecting Blue Light device targeting acne-causing bacteria, a Skin Rejuvenating Laser for anti-aging, and an Age-Defying Eye Wrinkle Correcting Laser aimed at reducing fine lines around the eyes. These products leverage advanced light technology, typically used in professional dermatological treatments, allowing users to achieve salon-quality results at home. TRIA Beauty markets its products through its e-commerce platform and various indirect sales channels, including television, retail locations, and physician offices. Founded in 2003 and headquartered in Dublin, California, TRIA Beauty serves customers across multiple countries, including the United States, Japan, and several European nations. The company previously operated under the name SpectraGenics, Inc. before rebranding in 2008.

Konarka Technologies, Inc. develops and advances nano-enabled polymer photovoltaic materials for commercial, industrial, government, and consumer applications. It provides standard products to serve portable power needs; and custom solutions, such as roll up chargers, personal accessories, and fold up chargers. The company's products are used in outdoor, portable power, indoor and remote sensing, and mission critical applications. It has strategic partnerships with Air Products, 24 Innovations, Kurz, SkyShades, Chevron, Merck, Toppan Forms, Dupont, Siemens, and the U.S. Air Force. Konarka Technologies, Inc. was founded in 2001 and is headquartered in Lowell, Massachusetts with business development offices in Asia. It has a research and development facility in Austria. The company has operations in the United States, Europe, and Asia.

CALIENT Technologies, Inc. specializes in the design and manufacture of high-density 3D MEMS (Micro-Electro-Mechanical Systems) optical circuit switching systems. These systems facilitate optical layer optimization in data centers and software-defined networks, serving a variety of sectors including service providers, cloud computing, content delivery, and government applications. The company offers a range of products, such as S-series optical circuit switches and an OEM subsystem solution that operates as a white label optical switching system. Additionally, CALIENT provides the LightConnect fabric manager, which allows data center operators to manage various optical circuit switch nodes. Their technology enables dynamic optical-layer sharing, optimization, and automation, thus improving the operational efficiency of high-performance test and network resources. Founded in 1999 and based in Goleta, California, CALIENT Technologies also offers professional services that include network design, installation, and training.

TRIA Beauty, Inc. specializes in developing and selling light-based medical devices designed for consumer use in skincare and beauty treatments. The company's primary offerings include a hand-held diode laser device for permanent hair removal, a Skin Perfecting Blue Light device targeting acne-causing bacteria, a Skin Rejuvenating Laser for anti-aging, and an Age-Defying Eye Wrinkle Correcting Laser aimed at reducing fine lines around the eyes. These products leverage advanced light technology, typically used in professional dermatological treatments, allowing users to achieve salon-quality results at home. TRIA Beauty markets its products through its e-commerce platform and various indirect sales channels, including television, retail locations, and physician offices. Founded in 2003 and headquartered in Dublin, California, TRIA Beauty serves customers across multiple countries, including the United States, Japan, and several European nations. The company previously operated under the name SpectraGenics, Inc. before rebranding in 2008.