Spring Mill Venture Partners

Spring Mill Venture Partners is a venture capital firm based in Carmel, Indiana, established in 2004. The firm specializes in seed and early-stage investments, primarily targeting high-growth companies within the information technology, healthcare technology, and life sciences sectors. Its investment focus is on businesses located in Indiana and the surrounding Midwest region, which includes Illinois, Kentucky, Michigan, and Ohio. Spring Mill Venture Partners aims to provide both capital and strategic support to help early-stage companies achieve sustainable growth and success.

Ken Green

Co-Founder and Managing Partner

Past deals in Indiana

Scale Computing

Series D in 2012
Scale Computing, Inc. specializes in edge computing, virtualization, and hyperconverged infrastructure solutions tailored for midsized companies. The company’s flagship product, the HC3 platform, consolidates servers, storage, and virtualization into a single, integrated system that simplifies management and enhances application performance. By leveraging self-healing and automation technologies, HC3 minimizes downtime and reduces the complexities associated with traditional IT infrastructure, such as separate virtualization and disaster recovery software. This approach allows organizations to improve application uptime while lowering overall costs. Founded in 2007 and headquartered in Indianapolis, Indiana, Scale Computing aims to enable clients to focus on application management rather than infrastructure concerns.

Scale Computing

Series B in 2010
Scale Computing, Inc. specializes in edge computing, virtualization, and hyperconverged infrastructure solutions tailored for midsized companies. The company’s flagship product, the HC3 platform, consolidates servers, storage, and virtualization into a single, integrated system that simplifies management and enhances application performance. By leveraging self-healing and automation technologies, HC3 minimizes downtime and reduces the complexities associated with traditional IT infrastructure, such as separate virtualization and disaster recovery software. This approach allows organizations to improve application uptime while lowering overall costs. Founded in 2007 and headquartered in Indianapolis, Indiana, Scale Computing aims to enable clients to focus on application management rather than infrastructure concerns.

Scale Computing

Series A in 2009
Scale Computing, Inc. specializes in edge computing, virtualization, and hyperconverged infrastructure solutions tailored for midsized companies. The company’s flagship product, the HC3 platform, consolidates servers, storage, and virtualization into a single, integrated system that simplifies management and enhances application performance. By leveraging self-healing and automation technologies, HC3 minimizes downtime and reduces the complexities associated with traditional IT infrastructure, such as separate virtualization and disaster recovery software. This approach allows organizations to improve application uptime while lowering overall costs. Founded in 2007 and headquartered in Indianapolis, Indiana, Scale Computing aims to enable clients to focus on application management rather than infrastructure concerns.

Perfinity Biosciences

Venture Round in 2008
Perfinity Biosciences, Inc. focuses on developing tools for protein sample preparation, offering a range of products designed to enhance reproducibility and efficiency. Its product portfolio includes immobilized enzymes, affinity reagents, optimized buffers, and software solutions. Notable offerings include Soluble Smart Digest, a stable soluble trypsin for quick and consistent digestions, and Mag Beads, tailored for proteomics applications. The QuicPrep platform combines immunoaffinity and trypsin digestion in a single process, while Flash Digest provides a rapid and stable immobilized trypsin reactor. Additionally, the Workstation automates protein separations and mass spectrometry sample preparation. Founded in 2004 and based in West Lafayette, Indiana, the company was previously known as QuadraSpec, Inc. until its name change in March 2010.

CS-Keys

Series A in 2008
CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Biostorage Technologies

Series A in 2007
BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany. Their mission is to provide their clients with world class, biorepository services, exceeding clients’ expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples.

Biostorage Technologies

Venture Round in 2007
BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany. Their mission is to provide their clients with world class, biorepository services, exceeding clients’ expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples.

Perfinity Biosciences

Series A in 2005
Perfinity Biosciences, Inc. focuses on developing tools for protein sample preparation, offering a range of products designed to enhance reproducibility and efficiency. Its product portfolio includes immobilized enzymes, affinity reagents, optimized buffers, and software solutions. Notable offerings include Soluble Smart Digest, a stable soluble trypsin for quick and consistent digestions, and Mag Beads, tailored for proteomics applications. The QuicPrep platform combines immunoaffinity and trypsin digestion in a single process, while Flash Digest provides a rapid and stable immobilized trypsin reactor. Additionally, the Workstation automates protein separations and mass spectrometry sample preparation. Founded in 2004 and based in West Lafayette, Indiana, the company was previously known as QuadraSpec, Inc. until its name change in March 2010.
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