Three Leaf Ventures

Three Leaf Ventures is a venture capital firm based in Denver, Colorado, founded in 2014. It specializes in investing across various stages, from seed to late-stage startups, with a particular focus on healthcare sectors such as telemedicine, healthcare technology, genomics, and digital health. The firm typically invests between $0.5 million and $2 million per deal, although it is open to investing as little as $0.1 million in startups and up to $5 million in select opportunities. As a subsidiary of The Broe Companies, Inc., Three Leaf Ventures emphasizes long-term partnerships, providing entrepreneurs with not only financial support but also access to a robust network of resources and industry connections.

Kiki Broe

Managing Partner

15 past transactions

Beddr Sleep

Series A in 2018
Beddr is a health technology company based in Mountain View, California, that focuses on improving sleep quality through an integrated digital approach. Founded in 2016 by experienced digital health entrepreneurs, Beddr combines clinical-grade sleep sensors with predictive analytics to deliver personalized insights and recommendations for users. By capturing and correlating various data points, the company aims to help individuals identify and address the underlying causes of their sleep issues. Supported by investors such as Three Leaf Ventures and the Stanford-StartX Fund, Beddr is dedicated to enhancing the quality of life for millions by providing innovative solutions to sleep-related challenges.

Gamelynx

Venture Round in 2018
Gamelynx Inc. is a Canadian company based in Waterloo that specializes in developing a digital gaming platform. This platform enables users to engage in board games and card games without the need for physical components. Additionally, Gamelynx focuses on creating team-based competitive mobile games and video games that aim to make eSports accessible across various platforms. Their offerings include cross-platform games that can be played on Windows, Mac, iOS, and Android, allowing gamers to connect and compete with others regardless of the device they are using.

Biolinq

Series A in 2017
Biolinq Inc. is a San Diego-based company that specializes in developing skin-applied electronic sensors for health monitoring. Founded in 2012, Biolinq focuses on creating a digital health platform that offers minimally invasive electrochemical biosensors. These sensors analyze biomarkers in interstitial fluid to deliver actionable health information, particularly for diabetic patients who need to monitor their blood glucose levels. By enabling continuous monitoring of multiple biomarkers, the company's technology aims to improve metabolic health and provide a more convenient alternative to traditional blood glucose monitoring methods.

CirrusMD

Series A in 2017
CirrusMD Inc. operates a healthcare communication platform that connects patients and doctors in the United States. Founded in 2012 and headquartered in Denver, Colorado, the CirrusMD platform allows patients to send secure messages, share images, and schedule video chats with local physicians, providing 24/7 access to medical care. The platform's text-first approach eliminates barriers to communication, enabling timely and convenient interaction with healthcare professionals. By prioritizing direct messaging and video consultations, CirrusMD aims to enhance the patient experience and improve access to frontline medical services. The company's technology is designed to facilitate a more personal and efficient way for patients to receive guidance and care beyond traditional primary care settings.

Cohero Health

Series A in 2016
Cohero Health, Inc. is a digital respiratory health company that focuses on improving the management of asthma and chronic obstructive pulmonary disease (COPD). Founded in 2012 and based in New York, the company offers a proprietary connected health platform that combines sensor-based technology with a mobile application. This platform includes the BreatheSmart app, which provides customized medication reminders, records inhaler usage, and tracks lung function, symptoms, and environmental conditions over time. Cohero Health's product suite features mSpirometer lung function sensors and HeroTracker, a Bluetooth-enabled inhaler tracker that monitors both control and rescue medications. Additionally, BreatheSmart Connect serves as a Software-as-a-Service solution for remote patient monitoring and communication, enhancing coordination between patients and healthcare providers. By utilizing these tools, Cohero Health aims to improve medication adherence and overall health outcomes for individuals with respiratory conditions.

Hint Health

Seed Round in 2016
Hint Health Inc. is a San Francisco-based company that specializes in developing a membership management platform tailored for direct care providers. Founded in 2013 by Zak Holdsworth and Graham Melcher, Hint Health offers tools that facilitate membership administration and billing, enabling healthcare providers to operate and manage their own plans effectively. This platform supports a range of offerings, including essential, plus, pro, and enterprise plans, allowing organizations to design and implement direct primary care programs. By empowering providers to compete directly with traditional insurance models, Hint Health aims to transform the healthcare system, enhancing cost efficiency, quality of care, and patient outcomes. The company also hosts the Hint Summit, a conference that gathers healthcare professionals and industry leaders to discuss and promote healthcare reform in the United States.

CirrusMD

Seed Round in 2016
CirrusMD Inc. operates a healthcare communication platform that connects patients and doctors in the United States. Founded in 2012 and headquartered in Denver, Colorado, the CirrusMD platform allows patients to send secure messages, share images, and schedule video chats with local physicians, providing 24/7 access to medical care. The platform's text-first approach eliminates barriers to communication, enabling timely and convenient interaction with healthcare professionals. By prioritizing direct messaging and video consultations, CirrusMD aims to enhance the patient experience and improve access to frontline medical services. The company's technology is designed to facilitate a more personal and efficient way for patients to receive guidance and care beyond traditional primary care settings.

Genomenon

Seed Round in 2016
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.

Cohero Health

Seed Round in 2015
Cohero Health, Inc. is a digital respiratory health company that focuses on improving the management of asthma and chronic obstructive pulmonary disease (COPD). Founded in 2012 and based in New York, the company offers a proprietary connected health platform that combines sensor-based technology with a mobile application. This platform includes the BreatheSmart app, which provides customized medication reminders, records inhaler usage, and tracks lung function, symptoms, and environmental conditions over time. Cohero Health's product suite features mSpirometer lung function sensors and HeroTracker, a Bluetooth-enabled inhaler tracker that monitors both control and rescue medications. Additionally, BreatheSmart Connect serves as a Software-as-a-Service solution for remote patient monitoring and communication, enhancing coordination between patients and healthcare providers. By utilizing these tools, Cohero Health aims to improve medication adherence and overall health outcomes for individuals with respiratory conditions.

Naked Labs

Seed Round in 2015
Naked Labs is a Silicon Valley-based startup focused on3D scanning, computer vision, and human-centered design. It uses infrared light to capture a 3D body model, which is visualized on the Naked app. The company was founded in 2015 and is headquartered in Redwood City, California.

inui

Series B in 2015
inui Health is a consumer medical diagnostics company located in Silicon Valley, focused on making medical-grade information accessible to individuals at any time and place. The company has developed a cloud-based diagnostic platform that operates in a mobile environment, allowing consumers to access their health information easily. Their products aim to assist users in detecting health complications early, monitoring their overall health, and sharing pertinent information with healthcare providers for timely interventions. The first product to be launched is the inui In-Home Urine Analysis test system, which offers immediate lab test results for patients and physicians. These innovations empower consumers to manage their health and monitor various conditions, including kidney function and urinary tract infections.

CirrusMD

Seed Round in 2015
CirrusMD Inc. operates a healthcare communication platform that connects patients and doctors in the United States. Founded in 2012 and headquartered in Denver, Colorado, the CirrusMD platform allows patients to send secure messages, share images, and schedule video chats with local physicians, providing 24/7 access to medical care. The platform's text-first approach eliminates barriers to communication, enabling timely and convenient interaction with healthcare professionals. By prioritizing direct messaging and video consultations, CirrusMD aims to enhance the patient experience and improve access to frontline medical services. The company's technology is designed to facilitate a more personal and efficient way for patients to receive guidance and care beyond traditional primary care settings.

Invitae

Series F in 2014
Invitae is a genetic information company focused on integrating genetic insights into everyday medical practice to enhance healthcare quality for a large population. The company specializes in genetic diagnostics for hereditary disorders, offering a comprehensive service that consolidates multiple genetic tests into a single platform. Invitae's offerings include assessments for genes linked to hereditary cancer, neurological disorders, cardiovascular conditions, pediatric issues, metabolic disorders, and other hereditary ailments. By providing high-quality testing with quicker turnaround times and competitive pricing, Invitae aims to make genetic testing more accessible and effective for patients and healthcare providers alike.

Hint Health

Angel Round in 2014
Hint Health Inc. is a San Francisco-based company that specializes in developing a membership management platform tailored for direct care providers. Founded in 2013 by Zak Holdsworth and Graham Melcher, Hint Health offers tools that facilitate membership administration and billing, enabling healthcare providers to operate and manage their own plans effectively. This platform supports a range of offerings, including essential, plus, pro, and enterprise plans, allowing organizations to design and implement direct primary care programs. By empowering providers to compete directly with traditional insurance models, Hint Health aims to transform the healthcare system, enhancing cost efficiency, quality of care, and patient outcomes. The company also hosts the Hint Summit, a conference that gathers healthcare professionals and industry leaders to discuss and promote healthcare reform in the United States.

inui

Series A in 2013
inui Health is a consumer medical diagnostics company located in Silicon Valley, focused on making medical-grade information accessible to individuals at any time and place. The company has developed a cloud-based diagnostic platform that operates in a mobile environment, allowing consumers to access their health information easily. Their products aim to assist users in detecting health complications early, monitoring their overall health, and sharing pertinent information with healthcare providers for timely interventions. The first product to be launched is the inui In-Home Urine Analysis test system, which offers immediate lab test results for patients and physicians. These innovations empower consumers to manage their health and monitor various conditions, including kidney function and urinary tract infections.
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